4QLEA

Crystal structure of i14a dhfr mutant complexed with folate and nadp+
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
159
structure length
159
Chain Sequence
MISLIAALAVDRVAGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Free energy simulations of active-site mutants of dihydrofolate reductase.
pubmed doi rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase
source organism Escherichia coli
total genus 42
structure length 159
sequence length 159
chains with identical sequence B
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-06-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4qleA00
1RX1A 3NZAX 4KBNA 1PD8A 4KJKA 1VJ3A 1RB2A 1HFRA 1DHIA 3FYVX 3RO9A 5U26A 4DPDA 1DG5A 4LAEX 1DR7A 3TQBA 4XT6A 4XRBA 4X5JA 2ZZAA 3EEJA 5EAJA 3F0XX 5JA3A 3DFRA 1DR4A 3E0BA 4Q6AA 4H98A 2FZHA 5HQYA 3UM8A 3LG4A 3NZBX 3EIGA 3SGYA 2H2QA 1BOZA 3INVA 1RA1A 3GI2A 4M6JA 1DLSA 3NZ9X 4X5GA 2DHFA 2B3ZA 3ZPGA 3SQYX 4QLFA 3QLRA 3D84X 3NZDA 3IX9A 3QLWA 1E26A 4HOFA 1AOEA 3QLSA 1D1GA 3NXVA 1IA4A 2W9HA 1DHFA 2C2SA 3F0QX 4ELFA 3EX8A 1DRAA 5HVBA 3QG2A 4XT7A 1RX9A 1JUVA 3NXRA 3FQZA 4FGHA 1S3WA 3FL9A 8DFRA 3ZPCA 1S3VA 4M6KA 3L3RA 4HA7A 1DYJA 3DL5A 3JW5A 1DLRA 4PSYA 1KMVA 1J3JA 2KGKA 3ROAA 2G6VA 4P66A 4M6LA 4G95A 1RH3A 2D5NA 3F8YA 4G8ZX 3HBBA 3JTWA 4ELBA 3TQ9A 4I1NA 3DL6A 1DF7A 4P3QA 3JWMA 3NU0A 3QL3A 4EJ1A 4IXED 3SA2A 3IRMA 1RE7A 3JVXA 1RG7A 2BLAA 5JG0X 1OHJA 4LEKX 1RA8A 2XW7A 3QLYA 1DR6A 1MVTA 3R33A 1RC4A 3KJRA 4QLGA 3UM5A 1DREA 3CL9A 1U72A 5HSRA 1RB3A 3FQCA 1S3YA 1DDSA 1J3KA 2W3WA 2W9GA 4RGCA 4DP3A 2QK8A 5HPBA 2GD9A 4IXFX 4HOGA 1DYHA 4EIZA 1DG7A 1AO8A 3F8ZA 3JWCA 3D80A 3QL0A 4Q0DA 3DGAA 3GHVA 4KM2A 2AZNA 4OSGA 4NX6A 4TU5X 4HOEA 1DR1A 1IA2A 3F0UX 1RA3A 4ELGA 4KL9A 4KJJA 1CD2A 1CZ3A 3GHCA 5FDAA 2BLBA 1YHOA 4H97A 1TDRA 1ZDRA 2W3AA 4KD7A 3JWFA 3M09A 1M79A 1PDBA 4ELHA 1RF7A 4EILA 1DR2A 1AI9A 4OR7A 3NXYA 4KAKA 3F91A 1DHJA 4HA9A 3KY8A 1JOLA 4P68A 3QLZA 4LAHX 1RX6A 3K74A 4DPHA 5E8QA 3UM6A 3GHWA 3SH2A 2CD2A 1LY4A 1SEJA 3FRBX 4H96A 3FQFA 1DG8A 2W3MA 2W9SA 5ECCA 2OIPA 4LAGX 1IA3A 2W3VA 4GH8A 3TQ8A 2HM9A 1QZFA 3DATA 3QGTA 3FYWX 3KFYA 1DR3A 4XT8A 5DXVA 3QLXA 2LF1A 4IXGX 4XECX 4PTJA 4DFRA 4KNEA 3K2HA 1U71A 4G3MA 4EIGA 3SAIA 3DAUA 1HFPA 4P3RA 1DRFA 4DDRA 3S7AA 3CSEA 5HF0X 3FY8X 3IA4A 1LUDA 3F0BX 1OHKA 3SR5X 2ITHA 3GYFA 4I13A 3VCOA 5U27A 4QJCA 2D0KA 4CD2A 1IA1A 3TD8A 1JOMA 1S3UA 3NXXA 3NZCX 4M7VA 4X5FA 5CC9A 4KY8A 3FL8A 3FY9X 4QHVA 2P4GA 2FZJA 1DIUA 2FZIA 4KJLA 1RX3A 3FQVA 3F0SX 3EEMA 1RX4A 2ANQA 2DRCA 1VDRA 3JW3A 4XT4A 6DFRA 3OCHA 4ECKA 1U70A 4PSSA 3EELA 1J3IA 3Q1HA 4PTHA 1DYIA 3SA1A 4PSTA 2BL9A 3SRWX 3FRDX 3S9UA 3KJSA 4FHBA 3K47A 1DRBA 3NRRA 1BZFA 3CLBA 4Q67A 3S3VA 1MVSA 3QYLA 4KY4A 1RA2A 2INQA 3NZ6X 3N0HA 3RG9A 5CCCA 3HJ3A 7DFRA 4M2XA 3DG8A 3NXOA 4KEBA 1M78A 2O7PA 5HQZA 4Q0EA 3NTZA 1RA9A 3FS6A 3FQ0A 4X5HA 1PD9A 5HUIA 2BLCA 5ECXA 5HSUA 3SRQX 2L28A 1DYRA 1RX7A 2HQPA 5HI6A 4H95A 3FREX 3JWKA 3DRCA 3KGYA 1RX2A 1RX5A 5DFRA 1DR5A 2W9TA 5HT5A 2HXVA 1KLKA 4M7UA 3FRAX 3K45A 1LY3A 3M08A 2JYBA 3CD2A 4PDJA 4XE6X 3IRNA 4KYAA 5HT4A 2ANOA 1DDRA 4QJZD 3SRUX 4KLXA 1M7AA 1DISA 3IROA 3IA5A 3OAFA 3QYOA 3I3RA 2OBCA 3NXTA 5HF2X 4X5IA 1DAJA 1RX8A 3QFXA 4KFJA 5HVEA 3SRRX 4QLEA 3FRFX 4XT5A 2CIGA 2W3BA 3EEKA 4ELEA 4KM0A 2C2TA 4QI9A 4FGGA 3JSUA 3FQOA 3I8AX 4NX7A 1KMSA 3SRSX 1DRHA 3TQAA 1RD7A 3F0VX 1HFQA
chains in the Genus database with same CATH superfamily
1RX1A 3NZAX 4KBNA 1PD8A 4KJKA 1VJ3A 1RB2A 1HFRA 1DHIA 3FYVX 3RO9A 5U26A 4DPDA 1DG5A 4LAEX 1DR7A 3TQBA 4XT6A 4XRBA 4X5JA 2ZZAA 3EEJA 5EAJA 3F0XX 5JA3A 3DFRA 1DR4A 3E0BA 4Q6AA 4H98A 2FZHA 5HQYA 3UM8A 3LG4A 3NZBX 3EIGA 3SGYA 2H2QA 1BOZA 3INVA 1RA1A 3GI2A 4M6JA 1DLSA 3NZ9X 4X5GA 2DHFA 2B3ZA 3ZPGA 3SQYX 4QLFA 3QLRA 3D84X 3NZDA 3IX9A 3QLWA 1E26A 4HOFA 1AOEA 3QLSA 1D1GA 3NXVA 1IA4A 2W9HA 1DHFA 2C2SA 3F0QX 4ELFA 3EX8A 1DRAA 5HVBA 3QG2A 4XT7A 1RX9A 1JUVA 3NXRA 3FQZA 4FGHA 1S3WA 3FL9A 8DFRA 3ZPCA 1S3VA 4M6KA 3L3RA 4HA7A 1DYJA 3DL5A 3JW5A 1DLRA 4PSYA 1KMVA 1J3JA 2KGKA 3ROAA 2G6VA 4P66A 4M6LA 4G95A 1RH3A 2D5NA 3F8YA 4G8ZX 3HBBA 3JTWA 4ELBA 3TQ9A 4I1NA 3DL6A 1DF7A 4P3QA 3JWMA 3NU0A 3QL3A 4EJ1A 4IXED 3SA2A 3IRMA 1RE7A 3JVXA 1RG7A 2BLAA 5JG0X 1OHJA 4LEKX 1RA8A 2XW7A 3QLYA 1DR6A 1MVTA 3R33A 1RC4A 3KJRA 4QLGA 3UM5A 1DREA 3CL9A 1U72A 5HSRA 1RB3A 3FQCA 1S3YA 1DDSA 1J3KA 2W3WA 2W9GA 4RGCA 4DP3A 2QK8A 5HPBA 2GD9A 4IXFX 4HOGA 1DYHA 4EIZA 1DG7A 1AO8A 3F8ZA 3JWCA 3D80A 3QL0A 4Q0DA 3DGAA 3GHVA 4KM2A 2AZNA 4OSGA 4NX6A 4TU5X 4HOEA 1DR1A 1IA2A 3F0UX 1RA3A 4ELGA 4KL9A 4KJJA 1CD2A 1CZ3A 3GHCA 5FDAA 2BLBA 1YHOA 4H97A 1TDRA 1ZDRA 2W3AA 4KD7A 3JWFA 3M09A 1M79A 1PDBA 4ELHA 1RF7A 4EILA 1DR2A 1AI9A 4OR7A 3NXYA 4KAKA 3F91A 1DHJA 4HA9A 3KY8A 1JOLA 4P68A 3QLZA 4LAHX 1RX6A 3K74A 4DPHA 5E8QA 3UM6A 3GHWA 3SH2A 2CD2A 1LY4A 1SEJA 3FRBX 4H96A 3FQFA 1DG8A 2W3MA 2W9SA 5ECCA 2OIPA 4LAGX 1IA3A 2W3VA 4GH8A 3TQ8A 2HM9A 1QZFA 3DATA 3QGTA 3FYWX 3KFYA 1DR3A 4XT8A 5DXVA 3QLXA 2LF1A 4IXGX 4XECX 4PTJA 4DFRA 4KNEA 3K2HA 1U71A 4G3MA 4EIGA 3SAIA 3DAUA 1HFPA 4P3RA 1DRFA 4DDRA 3S7AA 3CSEA 5HF0X 3FY8X 3IA4A 1LUDA 3F0BX 1OHKA 3SR5X 2ITHA 3GYFA 4I13A 3VCOA 5U27A 4QJCA 2D0KA 4CD2A 1IA1A 3TD8A 1JOMA 1S3UA 3NXXA 3NZCX 4M7VA 4X5FA 5CC9A 4KY8A 3FL8A 3FY9X 4QHVA 2P4GA 2FZJA 1DIUA 2FZIA 4KJLA 1RX3A 3FQVA 3F0SX 3EEMA 1RX4A 2ANQA 2DRCA 1VDRA 3JW3A 4XT4A 6DFRA 3OCHA 4ECKA 1U70A 4PSSA 3EELA 1J3IA 3Q1HA 4PTHA 1DYIA 3SA1A 4PSTA 2BL9A 3SRWX 3FRDX 3S9UA 3KJSA 4FHBA 3K47A 1DRBA 3NRRA 1BZFA 3CLBA 4Q67A 3S3VA 1MVSA 3QYLA 4KY4A 1RA2A 2INQA 3NZ6X 3N0HA 3RG9A 5CCCA 3HJ3A 7DFRA 4M2XA 3DG8A 3NXOA 4KEBA 1M78A 2O7PA 5HQZA 4Q0EA 3NTZA 1RA9A 3FS6A 3FQ0A 4X5HA 1PD9A 5HUIA 2BLCA 5ECXA 5HSUA 3SRQX 2L28A 1DYRA 1RX7A 2HQPA 5HI6A 4H95A 3FREX 3JWKA 3DRCA 3KGYA 1RX2A 1RX5A 5DFRA 1DR5A 2W9TA 5HT5A 2HXVA 1KLKA 4M7UA 3FRAX 3K45A 1LY3A 3M08A 2JYBA 3CD2A 4PDJA 4XE6X 3IRNA 4KYAA 5HT4A 2ANOA 1DDRA 4QJZD 3SRUX 4KLXA 1M7AA 1DISA 3IROA 3IA5A 3OAFA 3QYOA 3I3RA 2OBCA 3NXTA 5HF2X 4X5IA 1DAJA 1RX8A 3QFXA 4KFJA 5HVEA 3SRRX 4QLEA 3FRFX 4XT5A 2CIGA 2W3BA 3EEKA 4ELEA 4KM0A 2C2TA 4QI9A 4FGGA 3JSUA 3FQOA 3I8AX 4NX7A 1KMSA 3SRSX 1DRHA 3TQAA 1RD7A 3F0VX 1HFQA
chains in the Genus database with same CATH topology
1RX1A 3NZAX 4KBNA 1PD8A 4KJKA 1VJ3A 1RB2A 1HFRA 1DHIA 3FYVX 3RO9A 5U26A 4DPDA 1DG5A 4LAEX 1DR7A 3TQBA 4XT6A 4XRBA 4X5JA 2ZZAA 3EEJA 5EAJA 3F0XX 5JA3A 3DFRA 1DR4A 3E0BA 4Q6AA 4H98A 2FZHA 5HQYA 3UM8A 3LG4A 3NZBX 3EIGA 3SGYA 2H2QA 1BOZA 3INVA 1RA1A 3GI2A 4M6JA 1DLSA 3NZ9X 4X5GA 2DHFA 2B3ZA 3ZPGA 3SQYX 4QLFA 3QLRA 3D84X 3NZDA 3IX9A 3QLWA 1E26A 4HOFA 1AOEA 3QLSA 1D1GA 3NXVA 1IA4A 2W9HA 1DHFA 2C2SA 3F0QX 4ELFA 3EX8A 1DRAA 5HVBA 3QG2A 4XT7A 1RX9A 1JUVA 3NXRA 3FQZA 4FGHA 1S3WA 3FL9A 8DFRA 3ZPCA 1S3VA 4M6KA 3L3RA 4HA7A 1DYJA 3DL5A 3JW5A 1DLRA 4PSYA 1KMVA 1J3JA 2KGKA 3ROAA 2G6VA 4P66A 4M6LA 4G95A 1RH3A 2D5NA 3F8YA 4G8ZX 3HBBA 3JTWA 4ELBA 3TQ9A 4I1NA 3DL6A 1DF7A 4P3QA 3JWMA 3NU0A 3QL3A 4EJ1A 4IXED 3SA2A 3IRMA 1RE7A 3JVXA 1RG7A 2BLAA 5JG0X 1OHJA 4LEKX 1RA8A 2XW7A 3QLYA 1DR6A 1MVTA 3R33A 1RC4A 3KJRA 4QLGA 3UM5A 1DREA 3CL9A 1U72A 5HSRA 1RB3A 3FQCA 1S3YA 1DDSA 1J3KA 2W3WA 2W9GA 4RGCA 4DP3A 2QK8A 5HPBA 2GD9A 4IXFX 4HOGA 1DYHA 4EIZA 1DG7A 1AO8A 3F8ZA 3JWCA 3D80A 3QL0A 4Q0DA 3DGAA 3GHVA 4KM2A 2AZNA 4OSGA 4NX6A 4TU5X 4HOEA 1DR1A 1IA2A 3F0UX 1RA3A 4ELGA 4KL9A 4KJJA 1CD2A 1CZ3A 3GHCA 5FDAA 2BLBA 1YHOA 4H97A 1TDRA 1ZDRA 2W3AA 4KD7A 3JWFA 3M09A 1M79A 1PDBA 4ELHA 1RF7A 4EILA 1DR2A 1AI9A 4OR7A 3NXYA 4KAKA 3F91A 1DHJA 4HA9A 3KY8A 1JOLA 4P68A 3QLZA 4LAHX 1RX6A 3K74A 4DPHA 5E8QA 3UM6A 3GHWA 3SH2A 2CD2A 1LY4A 1SEJA 3FRBX 4H96A 3FQFA 1DG8A 2W3MA 2W9SA 5ECCA 2OIPA 4LAGX 1IA3A 2W3VA 4GH8A 3TQ8A 2HM9A 1QZFA 3DATA 3QGTA 3FYWX 3KFYA 1DR3A 4XT8A 5DXVA 3QLXA 2LF1A 4IXGX 4XECX 4PTJA 4DFRA 4KNEA 3K2HA 1U71A 4G3MA 4EIGA 3SAIA 3DAUA 1HFPA 4P3RA 1DRFA 4DDRA 3S7AA 3CSEA 5HF0X 3FY8X 3IA4A 1LUDA 3F0BX 1OHKA 3SR5X 2ITHA 3GYFA 4I13A 3VCOA 5U27A 4QJCA 2D0KA 4CD2A 1IA1A 3TD8A 1JOMA 1S3UA 3NXXA 3NZCX 4M7VA 4X5FA 5CC9A 4KY8A 3FL8A 3FY9X 4QHVA 2P4GA 2FZJA 1DIUA 2FZIA 4KJLA 1RX3A 3FQVA 3F0SX 3EEMA 1RX4A 2ANQA 2DRCA 1VDRA 3JW3A 4XT4A 6DFRA 3OCHA 4ECKA 1U70A 4PSSA 3EELA 1J3IA 3Q1HA 4PTHA 1DYIA 3SA1A 4PSTA 2BL9A 3SRWX 3FRDX 3S9UA 3KJSA 4FHBA 3K47A 1DRBA 3NRRA 1BZFA 3CLBA 4Q67A 3S3VA 1MVSA 3QYLA 4KY4A 1RA2A 2INQA 3NZ6X 3N0HA 3RG9A 5CCCA 3HJ3A 7DFRA 4M2XA 3DG8A 3NXOA 4KEBA 1M78A 2O7PA 5HQZA 4Q0EA 3NTZA 1RA9A 3FS6A 3FQ0A 4X5HA 1PD9A 5HUIA 2BLCA 5ECXA 5HSUA 3SRQX 2L28A 1DYRA 1RX7A 2HQPA 5HI6A 4H95A 3FREX 3JWKA 3DRCA 3KGYA 1RX2A 1RX5A 5DFRA 1DR5A 2W9TA 5HT5A 2HXVA 1KLKA 4M7UA 3FRAX 3K45A 1LY3A 3M08A 2JYBA 3CD2A 4PDJA 4XE6X 3IRNA 4KYAA 5HT4A 2ANOA 1DDRA 4QJZD 3SRUX 4KLXA 1M7AA 1DISA 3IROA 3IA5A 3OAFA 3QYOA 3I3RA 2OBCA 3NXTA 5HF2X 4X5IA 1DAJA 1RX8A 3QFXA 4KFJA 5HVEA 3SRRX 4QLEA 3FRFX 4XT5A 2CIGA 2W3BA 3EEKA 4ELEA 4KM0A 2C2TA 4QI9A 4FGGA 3JSUA 3FQOA 3I8AX 4NX7A 1KMSA 3SRSX 1DRHA 3TQAA 1RD7A 3F0VX 1HFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RX1 A;  3NZA X;  4KBN A;  1PD8 A;  4KJK A;  1VJ3 A;  1RB2 A;  1HFR A;  1DHI A;  3FYV X;  3RO9 A;  5U26 A;  4DPD A;  1DG5 A;  4LAE X;  1DR7 A;  3TQB A;  4XT6 A;  4XRB A;  4X5J A;  2ZZA A;  3EEJ A;  5EAJ A;  3F0X X;  5JA3 A;  3DFR A;  1DR4 A;  3E0B A;  4Q6A A;  4H98 A;  2FZH A;  5HQY A;  3UM8 A;  3LG4 A;  3NZB X;  3EIG A;  3SGY A;  2H2Q A;  1BOZ A;  3INV A;  1RA1 A;  3GI2 A;  4M6J A;  1DLS A;  3NZ9 X;  4X5G A;  2DHF A;  2B3Z A;  3ZPG A;  3SQY X;  4QLF A;  3QLR A;  3D84 X;  3NZD A;  3IX9 A;  3QLW A;  1E26 A;  4HOF A;  1AOE A;  3QLS A;  1D1G A;  3NXV A;  1IA4 A;  2W9H A;  1DHF A;  2C2S A;  3F0Q X;  4ELF A;  3EX8 A;  1DRA A;  5HVB A;  3QG2 A;  4XT7 A;  1RX9 A;  1JUV A;  3NXR A;  3FQZ A;  4FGH A;  1S3W A;  3FL9 A;  8DFR A;  3ZPC A;  1S3V A;  4M6K A;  3L3R A;  4HA7 A;  1DYJ A;  3DL5 A;  3JW5 A;  1DLR A;  4PSY A;  1KMV A;  1J3J A;  2KGK A;  3ROA A;  2G6V A;  4P66 A;  4M6L A;  4G95 A;  1RH3 A;  2D5N A;  3F8Y A;  4G8Z X;  3HBB A;  3JTW A;  4ELB A;  3TQ9 A;  4I1N A;  3DL6 A;  1DF7 A;  4P3Q A;  3JWM A;  3NU0 A;  3QL3 A;  4EJ1 A;  4IXE D;  3SA2 A;  3IRM A;  1RE7 A;  3JVX A;  1RG7 A;  2BLA A;  5JG0 X;  1OHJ A;  4LEK X;  1RA8 A;  2XW7 A;  3QLY A;  1DR6 A;  1MVT A;  3R33 A;  1RC4 A;  3KJR A;  4QLG A;  3UM5 A;  1DRE A;  3CL9 A;  1U72 A;  5HSR A;  1RB3 A;  3FQC A;  1S3Y A;  1DDS A;  1J3K A;  2W3W A;  2W9G A;  4RGC A;  4DP3 A;  2QK8 A;  5HPB A;  2GD9 A;  4IXF X;  4HOG A;  1DYH A;  4EIZ A;  1DG7 A;  1AO8 A;  3F8Z A;  3JWC A;  3D80 A;  3QL0 A;  4Q0D A;  3DGA A;  3GHV A;  4KM2 A;  2AZN A;  4OSG A;  4NX6 A;  4TU5 X;  4HOE A;  1DR1 A;  1IA2 A;  3F0U X;  1RA3 A;  4ELG A;  4KL9 A;  4KJJ A;  1CD2 A;  1CZ3 A;  3GHC A;  5FDA A;  2BLB A;  1YHO A;  4H97 A;  1TDR A;  1ZDR A;  2W3A A;  4KD7 A;  3JWF A;  3M09 A;  1M79 A;  1PDB A;  4ELH A;  1RF7 A;  4EIL A;  1DR2 A;  1AI9 A;  4OR7 A;  3NXY A;  4KAK A;  3F91 A;  1DHJ A;  4HA9 A;  3KY8 A;  1JOL A;  4P68 A;  3QLZ A;  4LAH X;  1RX6 A;  3K74 A;  4DPH A;  5E8Q A;  3UM6 A;  3GHW A;  3SH2 A;  2CD2 A;  1LY4 A;  1SEJ A;  3FRB X;  4H96 A;  3FQF A;  1DG8 A;  2W3M A;  2W9S A;  5ECC A;  2OIP A;  4LAG X;  1IA3 A;  2W3V A;  4GH8 A;  3TQ8 A;  2HM9 A;  1QZF A;  3DAT A;  3QGT A;  3FYW X;  3KFY A;  1DR3 A;  4XT8 A;  5DXV A;  3QLX A;  2LF1 A;  4IXG X;  4XEC X;  4PTJ A;  4DFR A;  4KNE A;  3K2H A;  1U71 A;  4G3M A;  4EIG A;  3SAI A;  3DAU A;  1HFP A;  4P3R A;  1DRF A;  4DDR A;  3S7A A;  3CSE A;  5HF0 X;  3FY8 X;  3IA4 A;  1LUD A;  3F0B X;  1OHK A;  3SR5 X;  2ITH A;  3GYF A;  4I13 A;  3VCO A;  5U27 A;  4QJC A;  2D0K A;  4CD2 A;  1IA1 A;  3TD8 A;  1JOM A;  1S3U A;  3NXX A;  3NZC X;  4M7V A;  4X5F A;  5CC9 A;  4KY8 A;  3FL8 A;  3FY9 X;  4QHV A;  2P4G A;  2FZJ A;  1DIU A;  2FZI A;  4KJL A;  1RX3 A;  3FQV A;  3F0S X;  3EEM A;  1RX4 A;  2ANQ A;  2DRC A;  1VDR A;  3JW3 A;  4XT4 A;  6DFR A;  3OCH A;  4ECK A;  1U70 A;  4PSS A;  3EEL A;  1J3I A;  3Q1H A;  4PTH A;  1DYI A;  3SA1 A;  4PST A;  2BL9 A;  3SRW X;  3FRD X;  3S9U A;  3KJS A;  4FHB A;  3K47 A;  1DRB A;  3NRR A;  1BZF A;  3CLB A;  4Q67 A;  3S3V A;  1MVS A;  3QYL A;  4KY4 A;  1RA2 A;  2INQ A;  3NZ6 X;  3N0H A;  3RG9 A;  5CCC A;  3HJ3 A;  7DFR A;  4M2X A;  3DG8 A;  3NXO A;  4KEB A;  1M78 A;  2O7P A;  5HQZ A;  4Q0E A;  3NTZ A;  1RA9 A;  3FS6 A;  3FQ0 A;  4X5H A;  1PD9 A;  5HUI A;  2BLC A;  5ECX A;  5HSU A;  3SRQ X;  2L28 A;  1DYR A;  1RX7 A;  2HQP A;  5HI6 A;  4H95 A;  3FRE X;  3JWK A;  3DRC A;  3KGY A;  1RX2 A;  1RX5 A;  5DFR A;  1DR5 A;  2W9T A;  5HT5 A;  2HXV A;  1KLK A;  4M7U A;  3FRA X;  3K45 A;  1LY3 A;  3M08 A;  2JYB A;  3CD2 A;  4PDJ A;  4XE6 X;  3IRN A;  4KYA A;  5HT4 A;  2ANO A;  1DDR A;  4QJZ D;  3SRU X;  4KLX A;  1M7A A;  1DIS A;  3IRO A;  3IA5 A;  3OAF A;  3QYO A;  3I3R A;  2OBC A;  3NXT A;  5HF2 X;  4X5I A;  1DAJ A;  1RX8 A;  3QFX A;  4KFJ A;  5HVE A;  3SRR X;  4QLE A;  3FRF X;  4XT5 A;  2CIG A;  2W3B A;  3EEK A;  4ELE A;  4KM0 A;  2C2T A;  4QI9 A;  4FGG A;  3JSU A;  3FQO A;  3I8A X;  4NX7 A;  1KMS A;  3SRS X;  1DRH A;  3TQA A;  1RD7 A;  3F0V X;  1HFQ A; 
#chains in the Genus database with same CATH topology
 1RX1 A;  3NZA X;  4KBN A;  1PD8 A;  4KJK A;  1VJ3 A;  1RB2 A;  1HFR A;  1DHI A;  3FYV X;  3RO9 A;  5U26 A;  4DPD A;  1DG5 A;  4LAE X;  1DR7 A;  3TQB A;  4XT6 A;  4XRB A;  4X5J A;  2ZZA A;  3EEJ A;  5EAJ A;  3F0X X;  5JA3 A;  3DFR A;  1DR4 A;  3E0B A;  4Q6A A;  4H98 A;  2FZH A;  5HQY A;  3UM8 A;  3LG4 A;  3NZB X;  3EIG A;  3SGY A;  2H2Q A;  1BOZ A;  3INV A;  1RA1 A;  3GI2 A;  4M6J A;  1DLS A;  3NZ9 X;  4X5G A;  2DHF A;  2B3Z A;  3ZPG A;  3SQY X;  4QLF A;  3QLR A;  3D84 X;  3NZD A;  3IX9 A;  3QLW A;  1E26 A;  4HOF A;  1AOE A;  3QLS A;  1D1G A;  3NXV A;  1IA4 A;  2W9H A;  1DHF A;  2C2S A;  3F0Q X;  4ELF A;  3EX8 A;  1DRA A;  5HVB A;  3QG2 A;  4XT7 A;  1RX9 A;  1JUV A;  3NXR A;  3FQZ A;  4FGH A;  1S3W A;  3FL9 A;  8DFR A;  3ZPC A;  1S3V A;  4M6K A;  3L3R A;  4HA7 A;  1DYJ A;  3DL5 A;  3JW5 A;  1DLR A;  4PSY A;  1KMV A;  1J3J A;  2KGK A;  3ROA A;  2G6V A;  4P66 A;  4M6L A;  4G95 A;  1RH3 A;  2D5N A;  3F8Y A;  4G8Z X;  3HBB A;  3JTW A;  4ELB A;  3TQ9 A;  4I1N A;  3DL6 A;  1DF7 A;  4P3Q A;  3JWM A;  3NU0 A;  3QL3 A;  4EJ1 A;  4IXE D;  3SA2 A;  3IRM A;  1RE7 A;  3JVX A;  1RG7 A;  2BLA A;  5JG0 X;  1OHJ A;  4LEK X;  1RA8 A;  2XW7 A;  3QLY A;  1DR6 A;  1MVT A;  3R33 A;  1RC4 A;  3KJR A;  4QLG A;  3UM5 A;  1DRE A;  3CL9 A;  1U72 A;  5HSR A;  1RB3 A;  3FQC A;  1S3Y A;  1DDS A;  1J3K A;  2W3W A;  2W9G A;  4RGC A;  4DP3 A;  2QK8 A;  5HPB A;  2GD9 A;  4IXF X;  4HOG A;  1DYH A;  4EIZ A;  1DG7 A;  1AO8 A;  3F8Z A;  3JWC A;  3D80 A;  3QL0 A;  4Q0D A;  3DGA A;  3GHV A;  4KM2 A;  2AZN A;  4OSG A;  4NX6 A;  4TU5 X;  4HOE A;  1DR1 A;  1IA2 A;  3F0U X;  1RA3 A;  4ELG A;  4KL9 A;  4KJJ A;  1CD2 A;  1CZ3 A;  3GHC A;  5FDA A;  2BLB A;  1YHO A;  4H97 A;  1TDR A;  1ZDR A;  2W3A A;  4KD7 A;  3JWF A;  3M09 A;  1M79 A;  1PDB A;  4ELH A;  1RF7 A;  4EIL A;  1DR2 A;  1AI9 A;  4OR7 A;  3NXY A;  4KAK A;  3F91 A;  1DHJ A;  4HA9 A;  3KY8 A;  1JOL A;  4P68 A;  3QLZ A;  4LAH X;  1RX6 A;  3K74 A;  4DPH A;  5E8Q A;  3UM6 A;  3GHW A;  3SH2 A;  2CD2 A;  1LY4 A;  1SEJ A;  3FRB X;  4H96 A;  3FQF A;  1DG8 A;  2W3M A;  2W9S A;  5ECC A;  2OIP A;  4LAG X;  1IA3 A;  2W3V A;  4GH8 A;  3TQ8 A;  2HM9 A;  1QZF A;  3DAT A;  3QGT A;  3FYW X;  3KFY A;  1DR3 A;  4XT8 A;  5DXV A;  3QLX A;  2LF1 A;  4IXG X;  4XEC X;  4PTJ A;  4DFR A;  4KNE A;  3K2H A;  1U71 A;  4G3M A;  4EIG A;  3SAI A;  3DAU A;  1HFP A;  4P3R A;  1DRF A;  4DDR A;  3S7A A;  3CSE A;  5HF0 X;  3FY8 X;  3IA4 A;  1LUD A;  3F0B X;  1OHK A;  3SR5 X;  2ITH A;  3GYF A;  4I13 A;  3VCO A;  5U27 A;  4QJC A;  2D0K A;  4CD2 A;  1IA1 A;  3TD8 A;  1JOM A;  1S3U A;  3NXX A;  3NZC X;  4M7V A;  4X5F A;  5CC9 A;  4KY8 A;  3FL8 A;  3FY9 X;  4QHV A;  2P4G A;  2FZJ A;  1DIU A;  2FZI A;  4KJL A;  1RX3 A;  3FQV A;  3F0S X;  3EEM A;  1RX4 A;  2ANQ A;  2DRC A;  1VDR A;  3JW3 A;  4XT4 A;  6DFR A;  3OCH A;  4ECK A;  1U70 A;  4PSS A;  3EEL A;  1J3I A;  3Q1H A;  4PTH A;  1DYI A;  3SA1 A;  4PST A;  2BL9 A;  3SRW X;  3FRD X;  3S9U A;  3KJS A;  4FHB A;  3K47 A;  1DRB A;  3NRR A;  1BZF A;  3CLB A;  4Q67 A;  3S3V A;  1MVS A;  3QYL A;  4KY4 A;  1RA2 A;  2INQ A;  3NZ6 X;  3N0H A;  3RG9 A;  5CCC A;  3HJ3 A;  7DFR A;  4M2X A;  3DG8 A;  3NXO A;  4KEB A;  1M78 A;  2O7P A;  5HQZ A;  4Q0E A;  3NTZ A;  1RA9 A;  3FS6 A;  3FQ0 A;  4X5H A;  1PD9 A;  5HUI A;  2BLC A;  5ECX A;  5HSU A;  3SRQ X;  2L28 A;  1DYR A;  1RX7 A;  2HQP A;  5HI6 A;  4H95 A;  3FRE X;  3JWK A;  3DRC A;  3KGY A;  1RX2 A;  1RX5 A;  5DFR A;  1DR5 A;  2W9T A;  5HT5 A;  2HXV A;  1KLK A;  4M7U A;  3FRA X;  3K45 A;  1LY3 A;  3M08 A;  2JYB A;  3CD2 A;  4PDJ A;  4XE6 X;  3IRN A;  4KYA A;  5HT4 A;  2ANO A;  1DDR A;  4QJZ D;  3SRU X;  4KLX A;  1M7A A;  1DIS A;  3IRO A;  3IA5 A;  3OAF A;  3QYO A;  3I3R A;  2OBC A;  3NXT A;  5HF2 X;  4X5I A;  1DAJ A;  1RX8 A;  3QFX A;  4KFJ A;  5HVE A;  3SRR X;  4QLE A;  3FRF X;  4XT5 A;  2CIG A;  2W3B A;  3EEK A;  4ELE A;  4KM0 A;  2C2T A;  4QI9 A;  4FGG A;  3JSU A;  3FQO A;  3I8A X;  4NX7 A;  1KMS A;  3SRS X;  1DRH A;  3TQA A;  1RD7 A;  3F0V X;  1HFQ A; 
#chains in the Genus database with same CATH homology
 1RX1 A;  3NZA X;  4KBN A;  1PD8 A;  4KJK A;  1VJ3 A;  1RB2 A;  1HFR A;  1DHI A;  3FYV X;  3RO9 A;  5U26 A;  4DPD A;  1DG5 A;  4LAE X;  1DR7 A;  3TQB A;  4XT6 A;  4XRB A;  4X5J A;  2ZZA A;  3EEJ A;  5EAJ A;  3F0X X;  5JA3 A;  3DFR A;  1DR4 A;  3E0B A;  4Q6A A;  4H98 A;  2FZH A;  5HQY A;  3UM8 A;  3LG4 A;  3NZB X;  3EIG A;  3SGY A;  2H2Q A;  1BOZ A;  3INV A;  1RA1 A;  3GI2 A;  4M6J A;  1DLS A;  3NZ9 X;  4X5G A;  2DHF A;  2B3Z A;  3ZPG A;  3SQY X;  4QLF A;  3QLR A;  3D84 X;  3NZD A;  3IX9 A;  3QLW A;  1E26 A;  4HOF A;  1AOE A;  3QLS A;  1D1G A;  3NXV A;  1IA4 A;  2W9H A;  1DHF A;  2C2S A;  3F0Q X;  4ELF A;  3EX8 A;  1DRA A;  5HVB A;  3QG2 A;  4XT7 A;  1RX9 A;  1JUV A;  3NXR A;  3FQZ A;  4FGH A;  1S3W A;  3FL9 A;  8DFR A;  3ZPC A;  1S3V A;  4M6K A;  3L3R A;  4HA7 A;  1DYJ A;  3DL5 A;  3JW5 A;  1DLR A;  4PSY A;  1KMV A;  1J3J A;  2KGK A;  3ROA A;  2G6V A;  4P66 A;  4M6L A;  4G95 A;  1RH3 A;  2D5N A;  3F8Y A;  4G8Z X;  3HBB A;  3JTW A;  4ELB A;  3TQ9 A;  4I1N A;  3DL6 A;  1DF7 A;  4P3Q A;  3JWM A;  3NU0 A;  3QL3 A;  4EJ1 A;  4IXE D;  3SA2 A;  3IRM A;  1RE7 A;  3JVX A;  1RG7 A;  2BLA A;  5JG0 X;  1OHJ A;  4LEK X;  1RA8 A;  2XW7 A;  3QLY A;  1DR6 A;  1MVT A;  3R33 A;  1RC4 A;  3KJR A;  4QLG A;  3UM5 A;  1DRE A;  3CL9 A;  1U72 A;  5HSR A;  1RB3 A;  3FQC A;  1S3Y A;  1DDS A;  1J3K A;  2W3W A;  2W9G A;  4RGC A;  4DP3 A;  2QK8 A;  5HPB A;  2GD9 A;  4IXF X;  4HOG A;  1DYH A;  4EIZ A;  1DG7 A;  1AO8 A;  3F8Z A;  3JWC A;  3D80 A;  3QL0 A;  4Q0D A;  3DGA A;  3GHV A;  4KM2 A;  2AZN A;  4OSG A;  4NX6 A;  4TU5 X;  4HOE A;  1DR1 A;  1IA2 A;  3F0U X;  1RA3 A;  4ELG A;  4KL9 A;  4KJJ A;  1CD2 A;  1CZ3 A;  3GHC A;  5FDA A;  2BLB A;  1YHO A;  4H97 A;  1TDR A;  1ZDR A;  2W3A A;  4KD7 A;  3JWF A;  3M09 A;  1M79 A;  1PDB A;  4ELH A;  1RF7 A;  4EIL A;  1DR2 A;  1AI9 A;  4OR7 A;  3NXY A;  4KAK A;  3F91 A;  1DHJ A;  4HA9 A;  3KY8 A;  1JOL A;  4P68 A;  3QLZ A;  4LAH X;  1RX6 A;  3K74 A;  4DPH A;  5E8Q A;  3UM6 A;  3GHW A;  3SH2 A;  2CD2 A;  1LY4 A;  1SEJ A;  3FRB X;  4H96 A;  3FQF A;  1DG8 A;  2W3M A;  2W9S A;  5ECC A;  2OIP A;  4LAG X;  1IA3 A;  2W3V A;  4GH8 A;  3TQ8 A;  2HM9 A;  1QZF A;  3DAT A;  3QGT A;  3FYW X;  3KFY A;  1DR3 A;  4XT8 A;  5DXV A;  3QLX A;  2LF1 A;  4IXG X;  4XEC X;  4PTJ A;  4DFR A;  4KNE A;  3K2H A;  1U71 A;  4G3M A;  4EIG A;  3SAI A;  3DAU A;  1HFP A;  4P3R A;  1DRF A;  4DDR A;  3S7A A;  3CSE A;  5HF0 X;  3FY8 X;  3IA4 A;  1LUD A;  3F0B X;  1OHK A;  3SR5 X;  2ITH A;  3GYF A;  4I13 A;  3VCO A;  5U27 A;  4QJC A;  2D0K A;  4CD2 A;  1IA1 A;  3TD8 A;  1JOM A;  1S3U A;  3NXX A;  3NZC X;  4M7V A;  4X5F A;  5CC9 A;  4KY8 A;  3FL8 A;  3FY9 X;  4QHV A;  2P4G A;  2FZJ A;  1DIU A;  2FZI A;  4KJL A;  1RX3 A;  3FQV A;  3F0S X;  3EEM A;  1RX4 A;  2ANQ A;  2DRC A;  1VDR A;  3JW3 A;  4XT4 A;  6DFR A;  3OCH A;  4ECK A;  1U70 A;  4PSS A;  3EEL A;  1J3I A;  3Q1H A;  4PTH A;  1DYI A;  3SA1 A;  4PST A;  2BL9 A;  3SRW X;  3FRD X;  3S9U A;  3KJS A;  4FHB A;  3K47 A;  1DRB A;  3NRR A;  1BZF A;  3CLB A;  4Q67 A;  3S3V A;  1MVS A;  3QYL A;  4KY4 A;  1RA2 A;  2INQ A;  3NZ6 X;  3N0H A;  3RG9 A;  5CCC A;  3HJ3 A;  7DFR A;  4M2X A;  3DG8 A;  3NXO A;  4KEB A;  1M78 A;  2O7P A;  5HQZ A;  4Q0E A;  3NTZ A;  1RA9 A;  3FS6 A;  3FQ0 A;  4X5H A;  1PD9 A;  5HUI A;  2BLC A;  5ECX A;  5HSU A;  3SRQ X;  2L28 A;  1DYR A;  1RX7 A;  2HQP A;  5HI6 A;  4H95 A;  3FRE X;  3JWK A;  3DRC A;  3KGY A;  1RX2 A;  1RX5 A;  5DFR A;  1DR5 A;  2W9T A;  5HT5 A;  2HXV A;  1KLK A;  4M7U A;  3FRA X;  3K45 A;  1LY3 A;  3M08 A;  2JYB A;  3CD2 A;  4PDJ A;  4XE6 X;  3IRN A;  4KYA A;  5HT4 A;  2ANO A;  1DDR A;  4QJZ D;  3SRU X;  4KLX A;  1M7A A;  1DIS A;  3IRO A;  3IA5 A;  3OAF A;  3QYO A;  3I3R A;  2OBC A;  3NXT A;  5HF2 X;  4X5I A;  1DAJ A;  1RX8 A;  3QFX A;  4KFJ A;  5HVE A;  3SRR X;  4QLE A;  3FRF X;  4XT5 A;  2CIG A;  2W3B A;  3EEK A;  4ELE A;  4KM0 A;  2C2T A;  4QI9 A;  4FGG A;  3JSU A;  3FQO A;  3I8A X;  4NX7 A;  1KMS A;  3SRS X;  1DRH A;  3TQA A;  1RD7 A;  3F0V X;  1HFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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