4QLFA

Crystal structure of i14g dhfr mutant complexed with folate and nadp+
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
159
structure length
157
Chain Sequence
MISLIAALAVDRVGGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Free energy simulations of active-site mutants of dihydrofolate reductase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 45
structure length 157
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-06-12
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4qlfA00
3JTWA 3QLYA 3F0QX 2C2TA 4X5FA 1DRHA 4IXGX 1RX3A 3F8ZA 1DLRA 2W3AA 4KM0A 2L28A 4PDJA 1DDRA 3QFXA 3CD2A 4H96A 1JOMA 4XRBA 1DHIA 3NZ6X 3SGYA 2D5NA 3FY9X 3F8YA 3D84X 3IRMA 5U26A 3FQVA 4HOEA 3S3VA 1JUVA 3CSEA 3QYLA 1E26A 4KJJA 2ANQA 4G95A 1HFPA 3QYOA 4H97A 2HXVA 1IA1A 4QJCA 1DIUA 3F0VX 4RGCA 3SRUX 4ELEA 3NZBX 4PTJA 3JWKA 2BLBA 3NXOA 4QLEA 1AOEA 1RF7A 1S3WA 1S3VA 4KBNA 3ZPGA 1IA4A 1DG5A 3FRFX 1HFRA 2DHFA 3NRRA 3FQ0A 4PSSA 3UM6A 3ZPCA 5E8QA 4KY8A 1MVTA 3NTZA 3SA1A 1J3KA 1ZDRA 5HVBA 3SQYX 1SEJA 3OCHA 3F0SX 4KJLA 3QL0A 4H95A 4KFJA 4QI9A 5DXVA 1DISA 3CLBA 4HOFA 4DPDA 1CD2A 4QLFA 4PTHA 3FL8A 5DFRA 1AI9A 1DR5A 4NX7A 4LEKX 2XW7A 2DRCA 2KGKA 6DFRA 1RX8A 4DFRA 4ECKA 5ECXA 2FZJA 5HT5A 3DRCA 4M6KA 1DR2A 1DG8A 2ZZAA 4X5HA 1RA2A 3SRQX 4IXFX 1DRFA 3UM8A 2CIGA 2H2QA 1RA8A 2FZIA 2HQPA 1DRBA 3QLSA 4XT6A 3NU0A 1RA3A 1DYRA 4IXED 4HA7A 3QL3A 4XECX 1CZ3A 4QJZD 3I8AX 3GHWA 1OHJA 3JWCA 1RB2A 1VJ3A 3GI2A 3NXRA 3NZCX 4PSTA 4ELBA 5CC9A 1RX7A 4X5GA 1BZFA 4I13A 4P3RA 3VCOA 3FREX 5JG0X 3SRRX 2LF1A 2W3VA 1LY3A 1DR3A 3M08A 4ELGA 5HF0X 3SRWX 1DF7A 3FY8X 3FYVX 3Q1HA 3JSUA 3TQAA 2ITHA 1AO8A 2INQA 3K47A 1OHKA 2ANOA 3JW5A 1DAJA 4ELHA 3FRBX 3IROA 4DDRA 4OSGA 4G8ZX 4G3MA 4M2XA 1RE7A 3NZ9X 1MVSA 8DFRA 3NXVA 4PSYA 1KMSA 1DYHA 3QLZA 5HSRA 2W3WA 4EIZA 2FZHA 3TQ8A 4LAGX 1RX1A 3K74A 3NXYA 2OIPA 2P4GA 3KGYA 3FQOA 3FL9A 4FHBA 7DFRA 2GD9A 1U70A 4Q0EA 3QLXA 3SRSX 2C2SA 2O7PA 3JW3A 1DYIA 3SH2A 1LUDA 1KMVA 1RX9A 3JVXA 1U72A 5HT4A 4TU5X 1QZFA 3QLWA 3SA2A 2W3BA 4DP3A 3RO9A 3FQFA 1DR6A 4XT8A 1J3JA 3GHCA 3D80A 4HA9A 4I1NA 1RX5A 3EELA 4NX6A 1U71A 3TQBA 2B3ZA 3NXXA 3FYWX 1DLSA 3IX9A 1JOLA 3IA4A 3KY8A 4KLXA 4XT4A 4P3QA 3HJ3A 3N0HA 5CCCA 4FGHA 4GH8A 4Q0DA 3ROAA 3QLRA 4KY4A 1RG7A 3F0XX 1LY4A 3NZAX 4KAKA 1DHFA 3TQ9A 3EEKA 4KNEA 2BL9A 2QK8A 3UM5A 3EX8A 3EIGA 1M78A 2HM9A 1RA9A 3DATA 3DL6A 3FS6A 4LAHX 2JYBA 3EEJA 4QHVA 3SAIA 4FGGA 4LAEX 5EAJA 3FRAX 4M7VA 5HVEA 5HI6A 2W9TA 1VDRA 3KJSA 4EIGA 3FQZA 4P68A 1DG7A 1RX4A 5HPBA 2AZNA 3QGTA 1TDRA 3DGAA 3M09A 4KEBA 2W9SA 3OAFA 1DRAA 5ECCA 2W9HA 1RA1A 3CL9A 1RX2A 2D0KA 3L3RA 4M6LA 3K45A 4KD7A 3HBBA 4P66A 3GHVA 4DPHA 1DHJA 4CD2A 2BLAA 1RD7A 1RX6A 3IA5A 1PD9A 3E0BA 3INVA 3DFRA 1S3UA 3S9UA 2CD2A 5JA3A 1YHOA 1DR4A 5HUIA 3TD8A 5HSUA 1DDSA 4X5JA 2OBCA 4EILA 3NZDA 3KFYA 3KJRA 2G6VA 3SR5X 4X5IA 5HQYA 3K2HA 4KL9A 1PD8A 4Q6AA 1DYJA 3S7AA 1BOZA 4M6JA 4M7UA 3JWFA 3LG4A 3GYFA 3JWMA 3DL5A 4XT7A 2BLCA 3RG9A 3FQCA 3DAUA 4Q67A 1S3YA 4ELFA 1IA2A 1PDBA 1M7AA 1RH3A 5FDAA 3F0UX 4KJKA 1RC4A 4XT5A 5U27A 4OR7A 4H98A 3QG2A 1RB3A 4KYAA 1IA3A 3NXTA 4QLGA 1DREA 1M79A 3I3RA 4XE6X 4EJ1A 5HQZA 5HF2X 1KLKA 2W3MA 1DR7A 3DG8A 3F91A 1D1GA 4HOGA 3R33A 3IRNA 4KM2A 1J3IA 3EEMA 3FRDX 1HFQA 1DR1A 2W9GA 3F0BX
chains in the Genus database with same CATH superfamily
3JTWA 3QLYA 3F0QX 2C2TA 4X5FA 1DRHA 4IXGX 1RX3A 3F8ZA 1DLRA 2W3AA 4KM0A 2L28A 4PDJA 1DDRA 3QFXA 3CD2A 4H96A 1JOMA 4XRBA 1DHIA 3NZ6X 3SGYA 2D5NA 3FY9X 3F8YA 3D84X 3IRMA 5U26A 3FQVA 4HOEA 3S3VA 1JUVA 3CSEA 3QYLA 1E26A 4KJJA 2ANQA 4G95A 1HFPA 3QYOA 4H97A 2HXVA 1IA1A 4QJCA 1DIUA 3F0VX 4RGCA 3SRUX 4ELEA 3NZBX 4PTJA 3JWKA 2BLBA 3NXOA 4QLEA 1AOEA 1RF7A 1S3WA 1S3VA 4KBNA 3ZPGA 1IA4A 1DG5A 3FRFX 1HFRA 2DHFA 3NRRA 3FQ0A 4PSSA 3UM6A 3ZPCA 5E8QA 4KY8A 1MVTA 3NTZA 3SA1A 1J3KA 1ZDRA 5HVBA 3SQYX 1SEJA 3OCHA 3F0SX 4KJLA 3QL0A 4H95A 4KFJA 4QI9A 5DXVA 1DISA 3CLBA 4HOFA 4DPDA 1CD2A 4QLFA 4PTHA 3FL8A 5DFRA 1AI9A 1DR5A 4NX7A 4LEKX 2XW7A 2DRCA 2KGKA 6DFRA 1RX8A 4DFRA 4ECKA 5ECXA 2FZJA 5HT5A 3DRCA 4M6KA 1DR2A 1DG8A 2ZZAA 4X5HA 1RA2A 3SRQX 4IXFX 1DRFA 3UM8A 2CIGA 2H2QA 1RA8A 2FZIA 2HQPA 1DRBA 3QLSA 4XT6A 3NU0A 1RA3A 1DYRA 4IXED 4HA7A 3QL3A 4XECX 1CZ3A 4QJZD 3I8AX 3GHWA 1OHJA 3JWCA 1RB2A 1VJ3A 3GI2A 3NXRA 3NZCX 4PSTA 4ELBA 5CC9A 1RX7A 4X5GA 1BZFA 4I13A 4P3RA 3VCOA 3FREX 5JG0X 3SRRX 2LF1A 2W3VA 1LY3A 1DR3A 3M08A 4ELGA 5HF0X 3SRWX 1DF7A 3FY8X 3FYVX 3Q1HA 3JSUA 3TQAA 2ITHA 1AO8A 2INQA 3K47A 1OHKA 2ANOA 3JW5A 1DAJA 4ELHA 3FRBX 3IROA 4DDRA 4OSGA 4G8ZX 4G3MA 4M2XA 1RE7A 3NZ9X 1MVSA 8DFRA 3NXVA 4PSYA 1KMSA 1DYHA 3QLZA 5HSRA 2W3WA 4EIZA 2FZHA 3TQ8A 4LAGX 1RX1A 3K74A 3NXYA 2OIPA 2P4GA 3KGYA 3FQOA 3FL9A 4FHBA 7DFRA 2GD9A 1U70A 4Q0EA 3QLXA 3SRSX 2C2SA 2O7PA 3JW3A 1DYIA 3SH2A 1LUDA 1KMVA 1RX9A 3JVXA 1U72A 5HT4A 4TU5X 1QZFA 3QLWA 3SA2A 2W3BA 4DP3A 3RO9A 3FQFA 1DR6A 4XT8A 1J3JA 3GHCA 3D80A 4HA9A 4I1NA 1RX5A 3EELA 4NX6A 1U71A 3TQBA 2B3ZA 3NXXA 3FYWX 1DLSA 3IX9A 1JOLA 3IA4A 3KY8A 4KLXA 4XT4A 4P3QA 3HJ3A 3N0HA 5CCCA 4FGHA 4GH8A 4Q0DA 3ROAA 3QLRA 4KY4A 1RG7A 3F0XX 1LY4A 3NZAX 4KAKA 1DHFA 3TQ9A 3EEKA 4KNEA 2BL9A 2QK8A 3UM5A 3EX8A 3EIGA 1M78A 2HM9A 1RA9A 3DATA 3DL6A 3FS6A 4LAHX 2JYBA 3EEJA 4QHVA 3SAIA 4FGGA 4LAEX 5EAJA 3FRAX 4M7VA 5HVEA 5HI6A 2W9TA 1VDRA 3KJSA 4EIGA 3FQZA 4P68A 1DG7A 1RX4A 5HPBA 2AZNA 3QGTA 1TDRA 3DGAA 3M09A 4KEBA 2W9SA 3OAFA 1DRAA 5ECCA 2W9HA 1RA1A 3CL9A 1RX2A 2D0KA 3L3RA 4M6LA 3K45A 4KD7A 3HBBA 4P66A 3GHVA 4DPHA 1DHJA 4CD2A 2BLAA 1RD7A 1RX6A 3IA5A 1PD9A 3E0BA 3INVA 3DFRA 1S3UA 3S9UA 2CD2A 5JA3A 1YHOA 1DR4A 5HUIA 3TD8A 5HSUA 1DDSA 4X5JA 2OBCA 4EILA 3NZDA 3KFYA 3KJRA 2G6VA 3SR5X 4X5IA 5HQYA 3K2HA 4KL9A 1PD8A 4Q6AA 1DYJA 3S7AA 1BOZA 4M6JA 4M7UA 3JWFA 3LG4A 3GYFA 3JWMA 3DL5A 4XT7A 2BLCA 3RG9A 3FQCA 3DAUA 4Q67A 1S3YA 4ELFA 1IA2A 1PDBA 1M7AA 1RH3A 5FDAA 3F0UX 4KJKA 1RC4A 4XT5A 5U27A 4OR7A 4H98A 3QG2A 1RB3A 4KYAA 1IA3A 3NXTA 4QLGA 1DREA 1M79A 3I3RA 4XE6X 4EJ1A 5HQZA 5HF2X 1KLKA 2W3MA 1DR7A 3DG8A 3F91A 1D1GA 4HOGA 3R33A 3IRNA 4KM2A 1J3IA 3EEMA 3FRDX 1HFQA 1DR1A 2W9GA 3F0BX
chains in the Genus database with same CATH topology
3JTWA 3QLYA 3F0QX 2C2TA 4X5FA 1DRHA 4IXGX 1RX3A 3F8ZA 1DLRA 2W3AA 4KM0A 2L28A 4PDJA 1DDRA 3QFXA 3CD2A 4H96A 1JOMA 4XRBA 1DHIA 3NZ6X 3SGYA 2D5NA 3FY9X 3F8YA 3D84X 3IRMA 5U26A 3FQVA 4HOEA 3S3VA 1JUVA 3CSEA 3QYLA 1E26A 4KJJA 2ANQA 4G95A 1HFPA 3QYOA 4H97A 2HXVA 1IA1A 4QJCA 1DIUA 3F0VX 4RGCA 3SRUX 4ELEA 3NZBX 4PTJA 3JWKA 2BLBA 3NXOA 4QLEA 1AOEA 1RF7A 1S3WA 1S3VA 4KBNA 3ZPGA 1IA4A 1DG5A 3FRFX 1HFRA 2DHFA 3NRRA 3FQ0A 4PSSA 3UM6A 3ZPCA 5E8QA 4KY8A 1MVTA 3NTZA 3SA1A 1J3KA 1ZDRA 5HVBA 3SQYX 1SEJA 3OCHA 3F0SX 4KJLA 3QL0A 4H95A 4KFJA 4QI9A 5DXVA 1DISA 3CLBA 4HOFA 4DPDA 1CD2A 4QLFA 4PTHA 3FL8A 5DFRA 1AI9A 1DR5A 4NX7A 4LEKX 2XW7A 2DRCA 2KGKA 6DFRA 1RX8A 4DFRA 4ECKA 5ECXA 2FZJA 5HT5A 3DRCA 4M6KA 1DR2A 1DG8A 2ZZAA 4X5HA 1RA2A 3SRQX 4IXFX 1DRFA 3UM8A 2CIGA 2H2QA 1RA8A 2FZIA 2HQPA 1DRBA 3QLSA 4XT6A 3NU0A 1RA3A 1DYRA 4IXED 4HA7A 3QL3A 4XECX 1CZ3A 4QJZD 3I8AX 3GHWA 1OHJA 3JWCA 1RB2A 1VJ3A 3GI2A 3NXRA 3NZCX 4PSTA 4ELBA 5CC9A 1RX7A 4X5GA 1BZFA 4I13A 4P3RA 3VCOA 3FREX 5JG0X 3SRRX 2LF1A 2W3VA 1LY3A 1DR3A 3M08A 4ELGA 5HF0X 3SRWX 1DF7A 3FY8X 3FYVX 3Q1HA 3JSUA 3TQAA 2ITHA 1AO8A 2INQA 3K47A 1OHKA 2ANOA 3JW5A 1DAJA 4ELHA 3FRBX 3IROA 4DDRA 4OSGA 4G8ZX 4G3MA 4M2XA 1RE7A 3NZ9X 1MVSA 8DFRA 3NXVA 4PSYA 1KMSA 1DYHA 3QLZA 5HSRA 2W3WA 4EIZA 2FZHA 3TQ8A 4LAGX 1RX1A 3K74A 3NXYA 2OIPA 2P4GA 3KGYA 3FQOA 3FL9A 4FHBA 7DFRA 2GD9A 1U70A 4Q0EA 3QLXA 3SRSX 2C2SA 2O7PA 3JW3A 1DYIA 3SH2A 1LUDA 1KMVA 1RX9A 3JVXA 1U72A 5HT4A 4TU5X 1QZFA 3QLWA 3SA2A 2W3BA 4DP3A 3RO9A 3FQFA 1DR6A 4XT8A 1J3JA 3GHCA 3D80A 4HA9A 4I1NA 1RX5A 3EELA 4NX6A 1U71A 3TQBA 2B3ZA 3NXXA 3FYWX 1DLSA 3IX9A 1JOLA 3IA4A 3KY8A 4KLXA 4XT4A 4P3QA 3HJ3A 3N0HA 5CCCA 4FGHA 4GH8A 4Q0DA 3ROAA 3QLRA 4KY4A 1RG7A 3F0XX 1LY4A 3NZAX 4KAKA 1DHFA 3TQ9A 3EEKA 4KNEA 2BL9A 2QK8A 3UM5A 3EX8A 3EIGA 1M78A 2HM9A 1RA9A 3DATA 3DL6A 3FS6A 4LAHX 2JYBA 3EEJA 4QHVA 3SAIA 4FGGA 4LAEX 5EAJA 3FRAX 4M7VA 5HVEA 5HI6A 2W9TA 1VDRA 3KJSA 4EIGA 3FQZA 4P68A 1DG7A 1RX4A 5HPBA 2AZNA 3QGTA 1TDRA 3DGAA 3M09A 4KEBA 2W9SA 3OAFA 1DRAA 5ECCA 2W9HA 1RA1A 3CL9A 1RX2A 2D0KA 3L3RA 4M6LA 3K45A 4KD7A 3HBBA 4P66A 3GHVA 4DPHA 1DHJA 4CD2A 2BLAA 1RD7A 1RX6A 3IA5A 1PD9A 3E0BA 3INVA 3DFRA 1S3UA 3S9UA 2CD2A 5JA3A 1YHOA 1DR4A 5HUIA 3TD8A 5HSUA 1DDSA 4X5JA 2OBCA 4EILA 3NZDA 3KFYA 3KJRA 2G6VA 3SR5X 4X5IA 5HQYA 3K2HA 4KL9A 1PD8A 4Q6AA 1DYJA 3S7AA 1BOZA 4M6JA 4M7UA 3JWFA 3LG4A 3GYFA 3JWMA 3DL5A 4XT7A 2BLCA 3RG9A 3FQCA 3DAUA 4Q67A 1S3YA 4ELFA 1IA2A 1PDBA 1M7AA 1RH3A 5FDAA 3F0UX 4KJKA 1RC4A 4XT5A 5U27A 4OR7A 4H98A 3QG2A 1RB3A 4KYAA 1IA3A 3NXTA 4QLGA 1DREA 1M79A 3I3RA 4XE6X 4EJ1A 5HQZA 5HF2X 1KLKA 2W3MA 1DR7A 3DG8A 3F91A 1D1GA 4HOGA 3R33A 3IRNA 4KM2A 1J3IA 3EEMA 3FRDX 1HFQA 1DR1A 2W9GA 3F0BX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3JTW A;  3QLY A;  3F0Q X;  2C2T A;  4X5F A;  1DRH A;  4IXG X;  1RX3 A;  3F8Z A;  1DLR A;  2W3A A;  4KM0 A;  2L28 A;  4PDJ A;  1DDR A;  3QFX A;  3CD2 A;  4H96 A;  1JOM A;  4XRB A;  1DHI A;  3NZ6 X;  3SGY A;  2D5N A;  3FY9 X;  3F8Y A;  3D84 X;  3IRM A;  5U26 A;  3FQV A;  4HOE A;  3S3V A;  1JUV A;  3CSE A;  3QYL A;  1E26 A;  4KJJ A;  2ANQ A;  4G95 A;  1HFP A;  3QYO A;  4H97 A;  2HXV A;  1IA1 A;  4QJC A;  1DIU A;  3F0V X;  4RGC A;  3SRU X;  4ELE A;  3NZB X;  4PTJ A;  3JWK A;  2BLB A;  3NXO A;  4QLE A;  1AOE A;  1RF7 A;  1S3W A;  1S3V A;  4KBN A;  3ZPG A;  1IA4 A;  1DG5 A;  3FRF X;  1HFR A;  2DHF A;  3NRR A;  3FQ0 A;  4PSS A;  3UM6 A;  3ZPC A;  5E8Q A;  4KY8 A;  1MVT A;  3NTZ A;  3SA1 A;  1J3K A;  1ZDR A;  5HVB A;  3SQY X;  1SEJ A;  3OCH A;  3F0S X;  4KJL A;  3QL0 A;  4H95 A;  4KFJ A;  4QI9 A;  5DXV A;  1DIS A;  3CLB A;  4HOF A;  4DPD A;  1CD2 A;  4QLF A;  4PTH A;  3FL8 A;  5DFR A;  1AI9 A;  1DR5 A;  4NX7 A;  4LEK X;  2XW7 A;  2DRC A;  2KGK A;  6DFR A;  1RX8 A;  4DFR A;  4ECK A;  5ECX A;  2FZJ A;  5HT5 A;  3DRC A;  4M6K A;  1DR2 A;  1DG8 A;  2ZZA A;  4X5H A;  1RA2 A;  3SRQ X;  4IXF X;  1DRF A;  3UM8 A;  2CIG A;  2H2Q A;  1RA8 A;  2FZI A;  2HQP A;  1DRB A;  3QLS A;  4XT6 A;  3NU0 A;  1RA3 A;  1DYR A;  4IXE D;  4HA7 A;  3QL3 A;  4XEC X;  1CZ3 A;  4QJZ D;  3I8A X;  3GHW A;  1OHJ A;  3JWC A;  1RB2 A;  1VJ3 A;  3GI2 A;  3NXR A;  3NZC X;  4PST A;  4ELB A;  5CC9 A;  1RX7 A;  4X5G A;  1BZF A;  4I13 A;  4P3R A;  3VCO A;  3FRE X;  5JG0 X;  3SRR X;  2LF1 A;  2W3V A;  1LY3 A;  1DR3 A;  3M08 A;  4ELG A;  5HF0 X;  3SRW X;  1DF7 A;  3FY8 X;  3FYV X;  3Q1H A;  3JSU A;  3TQA A;  2ITH A;  1AO8 A;  2INQ A;  3K47 A;  1OHK A;  2ANO A;  3JW5 A;  1DAJ A;  4ELH A;  3FRB X;  3IRO A;  4DDR A;  4OSG A;  4G8Z X;  4G3M A;  4M2X A;  1RE7 A;  3NZ9 X;  1MVS A;  8DFR A;  3NXV A;  4PSY A;  1KMS A;  1DYH A;  3QLZ A;  5HSR A;  2W3W A;  4EIZ A;  2FZH A;  3TQ8 A;  4LAG X;  1RX1 A;  3K74 A;  3NXY A;  2OIP A;  2P4G A;  3KGY A;  3FQO A;  3FL9 A;  4FHB A;  7DFR A;  2GD9 A;  1U70 A;  4Q0E A;  3QLX A;  3SRS X;  2C2S A;  2O7P A;  3JW3 A;  1DYI A;  3SH2 A;  1LUD A;  1KMV A;  1RX9 A;  3JVX A;  1U72 A;  5HT4 A;  4TU5 X;  1QZF A;  3QLW A;  3SA2 A;  2W3B A;  4DP3 A;  3RO9 A;  3FQF A;  1DR6 A;  4XT8 A;  1J3J A;  3GHC A;  3D80 A;  4HA9 A;  4I1N A;  1RX5 A;  3EEL A;  4NX6 A;  1U71 A;  3TQB A;  2B3Z A;  3NXX A;  3FYW X;  1DLS A;  3IX9 A;  1JOL A;  3IA4 A;  3KY8 A;  4KLX A;  4XT4 A;  4P3Q A;  3HJ3 A;  3N0H A;  5CCC A;  4FGH A;  4GH8 A;  4Q0D A;  3ROA A;  3QLR A;  4KY4 A;  1RG7 A;  3F0X X;  1LY4 A;  3NZA X;  4KAK A;  1DHF A;  3TQ9 A;  3EEK A;  4KNE A;  2BL9 A;  2QK8 A;  3UM5 A;  3EX8 A;  3EIG A;  1M78 A;  2HM9 A;  1RA9 A;  3DAT A;  3DL6 A;  3FS6 A;  4LAH X;  2JYB A;  3EEJ A;  4QHV A;  3SAI A;  4FGG A;  4LAE X;  5EAJ A;  3FRA X;  4M7V A;  5HVE A;  5HI6 A;  2W9T A;  1VDR A;  3KJS A;  4EIG A;  3FQZ A;  4P68 A;  1DG7 A;  1RX4 A;  5HPB A;  2AZN A;  3QGT A;  1TDR A;  3DGA A;  3M09 A;  4KEB A;  2W9S A;  3OAF A;  1DRA A;  5ECC A;  2W9H A;  1RA1 A;  3CL9 A;  1RX2 A;  2D0K A;  3L3R A;  4M6L A;  3K45 A;  4KD7 A;  3HBB A;  4P66 A;  3GHV A;  4DPH A;  1DHJ A;  4CD2 A;  2BLA A;  1RD7 A;  1RX6 A;  3IA5 A;  1PD9 A;  3E0B A;  3INV A;  3DFR A;  1S3U A;  3S9U A;  2CD2 A;  5JA3 A;  1YHO A;  1DR4 A;  5HUI A;  3TD8 A;  5HSU A;  1DDS A;  4X5J A;  2OBC A;  4EIL A;  3NZD A;  3KFY A;  3KJR A;  2G6V A;  3SR5 X;  4X5I A;  5HQY A;  3K2H A;  4KL9 A;  1PD8 A;  4Q6A A;  1DYJ A;  3S7A A;  1BOZ A;  4M6J A;  4M7U A;  3JWF A;  3LG4 A;  3GYF A;  3JWM A;  3DL5 A;  4XT7 A;  2BLC A;  3RG9 A;  3FQC A;  3DAU A;  4Q67 A;  1S3Y A;  4ELF A;  1IA2 A;  1PDB A;  1M7A A;  1RH3 A;  5FDA A;  3F0U X;  4KJK A;  1RC4 A;  4XT5 A;  5U27 A;  4OR7 A;  4H98 A;  3QG2 A;  1RB3 A;  4KYA A;  1IA3 A;  3NXT A;  4QLG A;  1DRE A;  1M79 A;  3I3R A;  4XE6 X;  4EJ1 A;  5HQZ A;  5HF2 X;  1KLK A;  2W3M A;  1DR7 A;  3DG8 A;  3F91 A;  1D1G A;  4HOG A;  3R33 A;  3IRN A;  4KM2 A;  1J3I A;  3EEM A;  3FRD X;  1HFQ A;  1DR1 A;  2W9G A;  3F0B X; 
#chains in the Genus database with same CATH topology
 3JTW A;  3QLY A;  3F0Q X;  2C2T A;  4X5F A;  1DRH A;  4IXG X;  1RX3 A;  3F8Z A;  1DLR A;  2W3A A;  4KM0 A;  2L28 A;  4PDJ A;  1DDR A;  3QFX A;  3CD2 A;  4H96 A;  1JOM A;  4XRB A;  1DHI A;  3NZ6 X;  3SGY A;  2D5N A;  3FY9 X;  3F8Y A;  3D84 X;  3IRM A;  5U26 A;  3FQV A;  4HOE A;  3S3V A;  1JUV A;  3CSE A;  3QYL A;  1E26 A;  4KJJ A;  2ANQ A;  4G95 A;  1HFP A;  3QYO A;  4H97 A;  2HXV A;  1IA1 A;  4QJC A;  1DIU A;  3F0V X;  4RGC A;  3SRU X;  4ELE A;  3NZB X;  4PTJ A;  3JWK A;  2BLB A;  3NXO A;  4QLE A;  1AOE A;  1RF7 A;  1S3W A;  1S3V A;  4KBN A;  3ZPG A;  1IA4 A;  1DG5 A;  3FRF X;  1HFR A;  2DHF A;  3NRR A;  3FQ0 A;  4PSS A;  3UM6 A;  3ZPC A;  5E8Q A;  4KY8 A;  1MVT A;  3NTZ A;  3SA1 A;  1J3K A;  1ZDR A;  5HVB A;  3SQY X;  1SEJ A;  3OCH A;  3F0S X;  4KJL A;  3QL0 A;  4H95 A;  4KFJ A;  4QI9 A;  5DXV A;  1DIS A;  3CLB A;  4HOF A;  4DPD A;  1CD2 A;  4QLF A;  4PTH A;  3FL8 A;  5DFR A;  1AI9 A;  1DR5 A;  4NX7 A;  4LEK X;  2XW7 A;  2DRC A;  2KGK A;  6DFR A;  1RX8 A;  4DFR A;  4ECK A;  5ECX A;  2FZJ A;  5HT5 A;  3DRC A;  4M6K A;  1DR2 A;  1DG8 A;  2ZZA A;  4X5H A;  1RA2 A;  3SRQ X;  4IXF X;  1DRF A;  3UM8 A;  2CIG A;  2H2Q A;  1RA8 A;  2FZI A;  2HQP A;  1DRB A;  3QLS A;  4XT6 A;  3NU0 A;  1RA3 A;  1DYR A;  4IXE D;  4HA7 A;  3QL3 A;  4XEC X;  1CZ3 A;  4QJZ D;  3I8A X;  3GHW A;  1OHJ A;  3JWC A;  1RB2 A;  1VJ3 A;  3GI2 A;  3NXR A;  3NZC X;  4PST A;  4ELB A;  5CC9 A;  1RX7 A;  4X5G A;  1BZF A;  4I13 A;  4P3R A;  3VCO A;  3FRE X;  5JG0 X;  3SRR X;  2LF1 A;  2W3V A;  1LY3 A;  1DR3 A;  3M08 A;  4ELG A;  5HF0 X;  3SRW X;  1DF7 A;  3FY8 X;  3FYV X;  3Q1H A;  3JSU A;  3TQA A;  2ITH A;  1AO8 A;  2INQ A;  3K47 A;  1OHK A;  2ANO A;  3JW5 A;  1DAJ A;  4ELH A;  3FRB X;  3IRO A;  4DDR A;  4OSG A;  4G8Z X;  4G3M A;  4M2X A;  1RE7 A;  3NZ9 X;  1MVS A;  8DFR A;  3NXV A;  4PSY A;  1KMS A;  1DYH A;  3QLZ A;  5HSR A;  2W3W A;  4EIZ A;  2FZH A;  3TQ8 A;  4LAG X;  1RX1 A;  3K74 A;  3NXY A;  2OIP A;  2P4G A;  3KGY A;  3FQO A;  3FL9 A;  4FHB A;  7DFR A;  2GD9 A;  1U70 A;  4Q0E A;  3QLX A;  3SRS X;  2C2S A;  2O7P A;  3JW3 A;  1DYI A;  3SH2 A;  1LUD A;  1KMV A;  1RX9 A;  3JVX A;  1U72 A;  5HT4 A;  4TU5 X;  1QZF A;  3QLW A;  3SA2 A;  2W3B A;  4DP3 A;  3RO9 A;  3FQF A;  1DR6 A;  4XT8 A;  1J3J A;  3GHC A;  3D80 A;  4HA9 A;  4I1N A;  1RX5 A;  3EEL A;  4NX6 A;  1U71 A;  3TQB A;  2B3Z A;  3NXX A;  3FYW X;  1DLS A;  3IX9 A;  1JOL A;  3IA4 A;  3KY8 A;  4KLX A;  4XT4 A;  4P3Q A;  3HJ3 A;  3N0H A;  5CCC A;  4FGH A;  4GH8 A;  4Q0D A;  3ROA A;  3QLR A;  4KY4 A;  1RG7 A;  3F0X X;  1LY4 A;  3NZA X;  4KAK A;  1DHF A;  3TQ9 A;  3EEK A;  4KNE A;  2BL9 A;  2QK8 A;  3UM5 A;  3EX8 A;  3EIG A;  1M78 A;  2HM9 A;  1RA9 A;  3DAT A;  3DL6 A;  3FS6 A;  4LAH X;  2JYB A;  3EEJ A;  4QHV A;  3SAI A;  4FGG A;  4LAE X;  5EAJ A;  3FRA X;  4M7V A;  5HVE A;  5HI6 A;  2W9T A;  1VDR A;  3KJS A;  4EIG A;  3FQZ A;  4P68 A;  1DG7 A;  1RX4 A;  5HPB A;  2AZN A;  3QGT A;  1TDR A;  3DGA A;  3M09 A;  4KEB A;  2W9S A;  3OAF A;  1DRA A;  5ECC A;  2W9H A;  1RA1 A;  3CL9 A;  1RX2 A;  2D0K A;  3L3R A;  4M6L A;  3K45 A;  4KD7 A;  3HBB A;  4P66 A;  3GHV A;  4DPH A;  1DHJ A;  4CD2 A;  2BLA A;  1RD7 A;  1RX6 A;  3IA5 A;  1PD9 A;  3E0B A;  3INV A;  3DFR A;  1S3U A;  3S9U A;  2CD2 A;  5JA3 A;  1YHO A;  1DR4 A;  5HUI A;  3TD8 A;  5HSU A;  1DDS A;  4X5J A;  2OBC A;  4EIL A;  3NZD A;  3KFY A;  3KJR A;  2G6V A;  3SR5 X;  4X5I A;  5HQY A;  3K2H A;  4KL9 A;  1PD8 A;  4Q6A A;  1DYJ A;  3S7A A;  1BOZ A;  4M6J A;  4M7U A;  3JWF A;  3LG4 A;  3GYF A;  3JWM A;  3DL5 A;  4XT7 A;  2BLC A;  3RG9 A;  3FQC A;  3DAU A;  4Q67 A;  1S3Y A;  4ELF A;  1IA2 A;  1PDB A;  1M7A A;  1RH3 A;  5FDA A;  3F0U X;  4KJK A;  1RC4 A;  4XT5 A;  5U27 A;  4OR7 A;  4H98 A;  3QG2 A;  1RB3 A;  4KYA A;  1IA3 A;  3NXT A;  4QLG A;  1DRE A;  1M79 A;  3I3R A;  4XE6 X;  4EJ1 A;  5HQZ A;  5HF2 X;  1KLK A;  2W3M A;  1DR7 A;  3DG8 A;  3F91 A;  1D1G A;  4HOG A;  3R33 A;  3IRN A;  4KM2 A;  1J3I A;  3EEM A;  3FRD X;  1HFQ A;  1DR1 A;  2W9G A;  3F0B X; 
#chains in the Genus database with same CATH homology
 3JTW A;  3QLY A;  3F0Q X;  2C2T A;  4X5F A;  1DRH A;  4IXG X;  1RX3 A;  3F8Z A;  1DLR A;  2W3A A;  4KM0 A;  2L28 A;  4PDJ A;  1DDR A;  3QFX A;  3CD2 A;  4H96 A;  1JOM A;  4XRB A;  1DHI A;  3NZ6 X;  3SGY A;  2D5N A;  3FY9 X;  3F8Y A;  3D84 X;  3IRM A;  5U26 A;  3FQV A;  4HOE A;  3S3V A;  1JUV A;  3CSE A;  3QYL A;  1E26 A;  4KJJ A;  2ANQ A;  4G95 A;  1HFP A;  3QYO A;  4H97 A;  2HXV A;  1IA1 A;  4QJC A;  1DIU A;  3F0V X;  4RGC A;  3SRU X;  4ELE A;  3NZB X;  4PTJ A;  3JWK A;  2BLB A;  3NXO A;  4QLE A;  1AOE A;  1RF7 A;  1S3W A;  1S3V A;  4KBN A;  3ZPG A;  1IA4 A;  1DG5 A;  3FRF X;  1HFR A;  2DHF A;  3NRR A;  3FQ0 A;  4PSS A;  3UM6 A;  3ZPC A;  5E8Q A;  4KY8 A;  1MVT A;  3NTZ A;  3SA1 A;  1J3K A;  1ZDR A;  5HVB A;  3SQY X;  1SEJ A;  3OCH A;  3F0S X;  4KJL A;  3QL0 A;  4H95 A;  4KFJ A;  4QI9 A;  5DXV A;  1DIS A;  3CLB A;  4HOF A;  4DPD A;  1CD2 A;  4QLF A;  4PTH A;  3FL8 A;  5DFR A;  1AI9 A;  1DR5 A;  4NX7 A;  4LEK X;  2XW7 A;  2DRC A;  2KGK A;  6DFR A;  1RX8 A;  4DFR A;  4ECK A;  5ECX A;  2FZJ A;  5HT5 A;  3DRC A;  4M6K A;  1DR2 A;  1DG8 A;  2ZZA A;  4X5H A;  1RA2 A;  3SRQ X;  4IXF X;  1DRF A;  3UM8 A;  2CIG A;  2H2Q A;  1RA8 A;  2FZI A;  2HQP A;  1DRB A;  3QLS A;  4XT6 A;  3NU0 A;  1RA3 A;  1DYR A;  4IXE D;  4HA7 A;  3QL3 A;  4XEC X;  1CZ3 A;  4QJZ D;  3I8A X;  3GHW A;  1OHJ A;  3JWC A;  1RB2 A;  1VJ3 A;  3GI2 A;  3NXR A;  3NZC X;  4PST A;  4ELB A;  5CC9 A;  1RX7 A;  4X5G A;  1BZF A;  4I13 A;  4P3R A;  3VCO A;  3FRE X;  5JG0 X;  3SRR X;  2LF1 A;  2W3V A;  1LY3 A;  1DR3 A;  3M08 A;  4ELG A;  5HF0 X;  3SRW X;  1DF7 A;  3FY8 X;  3FYV X;  3Q1H A;  3JSU A;  3TQA A;  2ITH A;  1AO8 A;  2INQ A;  3K47 A;  1OHK A;  2ANO A;  3JW5 A;  1DAJ A;  4ELH A;  3FRB X;  3IRO A;  4DDR A;  4OSG A;  4G8Z X;  4G3M A;  4M2X A;  1RE7 A;  3NZ9 X;  1MVS A;  8DFR A;  3NXV A;  4PSY A;  1KMS A;  1DYH A;  3QLZ A;  5HSR A;  2W3W A;  4EIZ A;  2FZH A;  3TQ8 A;  4LAG X;  1RX1 A;  3K74 A;  3NXY A;  2OIP A;  2P4G A;  3KGY A;  3FQO A;  3FL9 A;  4FHB A;  7DFR A;  2GD9 A;  1U70 A;  4Q0E A;  3QLX A;  3SRS X;  2C2S A;  2O7P A;  3JW3 A;  1DYI A;  3SH2 A;  1LUD A;  1KMV A;  1RX9 A;  3JVX A;  1U72 A;  5HT4 A;  4TU5 X;  1QZF A;  3QLW A;  3SA2 A;  2W3B A;  4DP3 A;  3RO9 A;  3FQF A;  1DR6 A;  4XT8 A;  1J3J A;  3GHC A;  3D80 A;  4HA9 A;  4I1N A;  1RX5 A;  3EEL A;  4NX6 A;  1U71 A;  3TQB A;  2B3Z A;  3NXX A;  3FYW X;  1DLS A;  3IX9 A;  1JOL A;  3IA4 A;  3KY8 A;  4KLX A;  4XT4 A;  4P3Q A;  3HJ3 A;  3N0H A;  5CCC A;  4FGH A;  4GH8 A;  4Q0D A;  3ROA A;  3QLR A;  4KY4 A;  1RG7 A;  3F0X X;  1LY4 A;  3NZA X;  4KAK A;  1DHF A;  3TQ9 A;  3EEK A;  4KNE A;  2BL9 A;  2QK8 A;  3UM5 A;  3EX8 A;  3EIG A;  1M78 A;  2HM9 A;  1RA9 A;  3DAT A;  3DL6 A;  3FS6 A;  4LAH X;  2JYB A;  3EEJ A;  4QHV A;  3SAI A;  4FGG A;  4LAE X;  5EAJ A;  3FRA X;  4M7V A;  5HVE A;  5HI6 A;  2W9T A;  1VDR A;  3KJS A;  4EIG A;  3FQZ A;  4P68 A;  1DG7 A;  1RX4 A;  5HPB A;  2AZN A;  3QGT A;  1TDR A;  3DGA A;  3M09 A;  4KEB A;  2W9S A;  3OAF A;  1DRA A;  5ECC A;  2W9H A;  1RA1 A;  3CL9 A;  1RX2 A;  2D0K A;  3L3R A;  4M6L A;  3K45 A;  4KD7 A;  3HBB A;  4P66 A;  3GHV A;  4DPH A;  1DHJ A;  4CD2 A;  2BLA A;  1RD7 A;  1RX6 A;  3IA5 A;  1PD9 A;  3E0B A;  3INV A;  3DFR A;  1S3U A;  3S9U A;  2CD2 A;  5JA3 A;  1YHO A;  1DR4 A;  5HUI A;  3TD8 A;  5HSU A;  1DDS A;  4X5J A;  2OBC A;  4EIL A;  3NZD A;  3KFY A;  3KJR A;  2G6V A;  3SR5 X;  4X5I A;  5HQY A;  3K2H A;  4KL9 A;  1PD8 A;  4Q6A A;  1DYJ A;  3S7A A;  1BOZ A;  4M6J A;  4M7U A;  3JWF A;  3LG4 A;  3GYF A;  3JWM A;  3DL5 A;  4XT7 A;  2BLC A;  3RG9 A;  3FQC A;  3DAU A;  4Q67 A;  1S3Y A;  4ELF A;  1IA2 A;  1PDB A;  1M7A A;  1RH3 A;  5FDA A;  3F0U X;  4KJK A;  1RC4 A;  4XT5 A;  5U27 A;  4OR7 A;  4H98 A;  3QG2 A;  1RB3 A;  4KYA A;  1IA3 A;  3NXT A;  4QLG A;  1DRE A;  1M79 A;  3I3R A;  4XE6 X;  4EJ1 A;  5HQZ A;  5HF2 X;  1KLK A;  2W3M A;  1DR7 A;  3DG8 A;  3F91 A;  1D1G A;  4HOG A;  3R33 A;  3IRN A;  4KM2 A;  1J3I A;  3EEM A;  3FRD X;  1HFQ A;  1DR1 A;  2W9G A;  3F0B X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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