4RDDA

Co-crystal structure of shp2 in complex with a cefsulodin derivative
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
267
structure length
267
Chain Sequence
LYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 83
structure length 267
sequence length 267
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4rddA00
3ZM1A 2I3RA 2OZ5A 4QAPA 3EMUA 4H34A 4ZN5A 2SHPA 3O4UA 2Y96A 1ZCKA 1YWFA 3V0JA 3BRHA 3S4EA 3AWEA 1Q6MA 2I4GA 3F41A 3LJ8A 4RDDA 1QXKA 1OHDA 2R0BA 4QUMA 4RKKA 2B3OA 3GXGA 2CNHA 3QCFA 3ZMPA 1ZZWA 4GRYA 4WOHA 3QCCA 2OUDA 3V0GA 3D1OA 3NMEA 2Q05A 2B4SA 3RGQA 1G7FA 1XBOA 2FH7A 1PXHA 3I80A 2CM7A 4OHDA 2BIJA 2PBNA 3S3KA 1OEUA 1YTWA 2QDCA 5KA7A 4OHIA 2H04A 5KA4A 5K9VA 1G1GA 1VHRA 3AWFA 1L8GA 5GTJA 2F70A 2CNGA 2QBSA 2CFVA 3QCJA 5BZXA 1U24A 1NWLA 3QCEA 2B07A 4MBBA 3O4SA 5KA0A 1YGUA 2CMBA 2CM8A 4RI5A 5IBSA 4RHGA 3QCDA 1OEMX 1WCHA 1GWZA 1OEOX 2B4UA 2HCMA 3QCBA 4JBCA 1A5YA 2I3UA 3EB1A 3QKQA 1EENA 2PSZA 2AZRA 1J4XA 1G1HA 3F9BA 2F6YA 2E0TA 5J8RA 3BM8A 1OESA 2FJNA 2I4EA 4HJPA 1BZHA 4GE5A 4RI4A 5KA3A 2CJZA 3ZM0A 2I6MA 5KA8A 5KA1A 2VEWA 2PT0A 2F6TA 1Q6NA 4D3RA 4D3QA 4DGXA 3H2XA 4GFVA 2F6WA 2CMAA 4NYHA 2BV5A 2F71A 2OC3A 2QBRA 2A8BA 2IMGA 4D3PA 2NT2A 4GE2A 2I42A 4JMJA 1WAXA 2P6XA 3RGOA 1X24A 1SUGA 3V0EA 4ERCA 1ONZA 5KAAA 2ZN7A 2CM3A 4QBWA 5K24A 1JF7A 3D42A 2I6JA 4WTYA 3O3LA 4PYHA 3CM3A 2VEYA 3U96A 3SMEA 1G4US 4ICZA 1Q6TA 4WU3A 3GXHA 1OEVA 4S0GA 2QBPA 1M3GA 5K22A 1ONYA 2G6ZA 4QUNA 2QBQA 3QCNA 4OHHA 3S3EA 1T4JA 5KABA 3B7OA 1C85A 3F9AA 1XXVA 2GJTA 5KADA 4BPCA 2J17A 2HNPA 3SR9A 2I5XA 2C7SA 2H4VA 4KYRA 1Q1MA 2QCJA 4TVVA 2NZ6A 5EHRA 4B04A 4Z6BA 1NL9A 1PA9A 2BZLA 1RXDA 4AZ1A 3MOWA 4R0SA 2I1YA 1JLNA 3QCGA 2H03A 1FQ1A 1FPRA 3V0HA 2J16A 3OMHA 3BLTA 3V0IA 1T48A 1EEOA 1G1FA 4HRFA 2J16B 1WRMA 2B49A 2WGPA 5AWXA 1BZJA 3QCIA 1YPTA 1L8KA 1U25A 3O5XA 3I36A 1XRIA 3D44A 2F6VA 2CNIA 1G4WR 4QBEA 4I8NA 5BUGA 5KACA 3RZ2A 5BX1A 2VEUA 3M4UA 2QDMA 1G7GA 5BZZA 2M3VA 4BJOA 4JNBA 5KA9A 2PA5A 2QEPA 4GFUA 1C86A 1OETA 3F99A 3A5KA 4NWGA 4Y2EA 1C88A 3D1HA 3OLRA 2C46A 1KAKA 2CM2A 2CNEA 4PVGA 1Q6PA 4WU2A 1YZ4A 3AWGA 1FPZA 4DGPA 3QCLA 4RH9A 3PS5A 3QCKA 4Y14A 5K9WA 1OHEA 1QZ0A 3A5JA 4YR8B 2PQ5A 3ZMQA 1XXPA 2G59A 2I6PA 2QCTA 3F81A 3S3HA 2GWOA 3CWEA 1PTUA 2F6ZA 2FJMA 1C83A 4ZRTA 2GP0A 5LXQB 3EAXA 1U26A 3QKPA 3MMJA 2B4PA 5IBMA 1PTVA 4QAHA 1YN9A 2VEXA 1YGRA 3V0DA 1Q6SA 2I4HA 1GFYA 4H1OA 3QCMA 4NX8A 1AAXA 1OHCA 2CNFA 1RPMA 2P4DA 4GRZA 2OOQA 4OHLA 2RF6A 3ZM3A 2HC1A 3RO1A 1C84A 1NZ7A 1D5RA 1C87A 1NNYA 1MKPA 3S4OA 2HC2A 3ZM2A 1LYVA 4JMKA 4ZI4A 2PI7A 1PTTA 3N0AA 2H4KA 3D1QA 2I75A 3V0FA 2DXPA 5K23A 4KI9A 1V3AA 3I7ZA 1I9TA 2F46A 4GS0A 2BGEA 3O4TA 4YAAA 1KAVA 2HVLA 1NO6A 1Q6JA 4R30A 1LARA 2HB1A 2Q47A 5I6VA 2NV5A 3BLUA 3ZV2A 4HJQA 2BGDA 2NLKA 2H02A 3S3FA 2ESBA 2HXPA 3EZZA 2HNQA 1NWEA 4J51A 1YTSA 1PH0A 4IKCA 3MOZA 1BZCA 4KYQA 2A3KA 3EU0A 4NWFA 1ZCLA 2HY3A 1XM2A 2NT7A 2Y2FA 2CMCA 2AHSA 2I6OA 2ZMMA 2H4GA 5HDEA 1I57A 1P15A 5EHPA 4RH5A 1PYNA 2F6FA 2JJDA 5KA2A 2QDPA 1ECVA 2NTAA 3QCHA 1PTYA 2YDUA 4GE6A 1R6HA 1I9SA 4GWFA 4R0TA 1YTNA 2B4OA 5K25A 3D9CA 4OHEA 1ZC0A 2I6IA 2MBCA 5M43A 4NNDA 1T49A 1YFOA 5MMZB 1LQFA 1PA1A 2VEVA
chains in the Genus database with same CATH superfamily
3ZM1A 2I3RA 2OZ5A 4QAPA 3EMUA 4H34A 4ZN5A 2SHPA 3O4UA 2Y96A 1ZCKA 2WJPA 1YWFA 3V0JA 3BRHA 3S4EA 3AWEA 1Q6MA 1O5ZA 2I4GA 1W7KA 3F41A 3LJ8A 4RDDA 1QXKA 1OHDA 2R0BA 4QUMA 4UAGA 4RKKA 2B3OA 3GXGA 2CNHA 3QCFA 3ZMPA 1ZZWA 4GRYA 4CVLA 4WOHA 3QCCA 2OUDA 3V0GA 2UUOA 3D1OA 3NMEA 2Q05A 2B4SA 3RGQA 1G7FA 1XBOA 2FH7A 1PXHA 3I80A 2CM7A 4OHDA 2BIJA 3LK7A 2AM1A 2PBNA 3S3KA 1OEUA 1YTWA 2QDCA 5KA7A 5A5EA 4OHIA 2H04A 5KA4A 5K9VA 1G1GA 1VHRA 3AWFA 1L8GA 5GTJA 2F70A 2CNGA 2QBSA 2AM2A 2CFVA 3QCJA 5BZXA 1U24A 4CVKA 1NWLA 3QCEA 2B07A 4MBBA 3O4SA 5KA0A 1YGUA 2CMBA 2CM8A 4RI5A 5IBSA 1JBWA 4RHGA 3QCDA 1OEMX 1WCHA 1GWZA 1OEOX 2B4UA 2HCMA 2WTZA 3QCBA 4JBCA 1A5YA 2I3UA 1UAGA 3EB1A 3QKQA 1EENA 2PSZA 2AZRA 3PYZA 1J4XA 1G1HA 3F9BA 2F6YA 2E0TA 5J8RA 1E8CA 3BM8A 1OESA 2FJNA 2I4EA 4HJPA 1BZHA 4GE5A 4RI4A 5KA3A 2CJZA 3ZM0A 2I6MA 5KA8A 5KA1A 2VEWA 2PT0A 2F6TA 1Q6NA 1W78A 4D3RA 4D3QA 4DGXA 2Y68A 3H2XA 4GFVA 2F6WA 2CMAA 4HV4A 4NYHA 2BV5A 2F71A 1E0DA 2OC3A 2QBRA 2A8BA 2IMGA 4D3PA 2NT2A 4GE2A 2I42A 4JMJA 1WAXA 2P6XA 3RGOA 1X24A 1SUGA 3V0EA 4ERCA 1ONZA 5KAAA 2ZN7A 2CM3A 4QBWA 1J6UA 2VOSA 5K24A 1JF7A 3D42A 2I6JA 4WTYA 3UAGA 3O3LA 4PYHA 3CM3A 2VEYA 2F00A 5A5FA 3U96A 3SMEA 4C12A 1G4US 1P31A 4ICZA 1Q6TA 4WU3A 3GXHA 1OEVA 4S0GA 2QBPA 1M3GA 5K22A 1ONYA 2G6ZA 4QUNA 2QBQA 3QCNA 4OHHA 3S3EA 1T4JA 5KABA 3B7OA 1C85A 3F9AA 1XXVA 2GJTA 5KADA 4BPCA 2J17A 2HNPA 3SR9A 2I5XA 2C7SA 4BUCA 2H4VA 4KYRA 1Q1MA 2QCJA 4TVVA 2NZ6A 5EHRA 4B04A 4Z6BA 1NL9A 1PA9A 2BZLA 1RXDA 4AZ1A 3MOWA 4R0SA 2I1YA 1JLNA 3QCGA 2H03A 1FQ1A 1FPRA 3V0HA 2J16A 2GCBA 3OMHA 4ZIYA 3BLTA 3V0IA 1T48A 1EEOA 1G1FA 4HRFA 2J16B 1WRMA 2B49A 2WGPA 2VTDA 5AWXA 1BZJA 3QCIA 1YPTA 1L8KA 1U25A 3O5XA 3I36A 1XRIA 3D44A 2F6VA 2CNIA 4CVMA 1G4WR 1EEHA 4QBEA 4I8NA 1GQYA 5BUGA 5KACA 3RZ2A 2GC6A 5BX1A 2VEUA 3M4UA 2QDMA 1G7GA 2JFHA 5BZZA 2M3VA 4BJOA 4C13A 4JNBA 5KA9A 2PA5A 2QEPA 2VTEA 4GFUA 2XJAA 1C86A 2Y66A 1OETA 3F99A 3A5KA 4NWGA 4Y2EA 2JFFA 1C88A 2GCAA 3D1HA 3OLRA 2C46A 1KAKA 2CM2A 2CNEA 4PVGA 1Q6PA 4WU2A 1YZ4A 3AWGA 1FPZA 4DGPA 3QCLA 4RH9A 3PS5A 3QCKA 4Y14A 5K9WA 1OHEA 1QZ0A 3A5JA 4YR8B 2PQ5A 3ZMQA 1XXPA 2G59A 3NRSA 2I6PA 2QCTA 1P3DA 3N2AA 3F81A 3S3HA 2GWOA 3CWEA 1PTUA 2F6ZA 1GG4A 2FJMA 1C83A 4ZRTA 2XPCA 2GP0A 5LXQB 3EAXA 1U26A 3QKPA 3MMJA 2B4PA 5IBMA 1PTVA 4QAHA 1YN9A 2VEXA 1YGRA 3V0DA 1Q6SA 2I4HA 1GFYA 4H1OA 3QCMA 4NX8A 1GQQA 1AAXA 3QCZA 1OHCA 2CNFA 1RPMA 2P4DA 4GRZA 3HN7A 2OOQA 4OHLA 2RF6A 3ZM3A 2HC1A 3RO1A 1C84A 1NZ7A 1D5RA 1C87A 1NNYA 2Y67A 1MKPA 3S4OA 2HC2A 3ZM2A 1LYVA 4JMKA 4QF5A 4ZI4A 2PI7A 1PTTA 3N0AA 2H4KA 3D1QA 2I75A 2VORA 3V0FA 3MVNA 2DXPA 5K23A 4KI9A 1V3AA 3I7ZA 1I9TA 2F46A 4GS0A 2BGEA 3O4TA 4YAAA 4BUBA 1JBVA 1KAVA 2HVLA 1NO6A 1Q6JA 4R30A 1LARA 2HB1A 2Q47A 5I6VA 2NV5A 3BLUA 3ZV2A 4HJQA 4QDIA 2BGDA 2X5OA 2NLKA 2H02A 3S3FA 2ESBA 2HXPA 3EZZA 2HNQA 1NWEA 4J51A 1YTSA 1PH0A 3ZM5A 4IKCA 3MOZA 1BZCA 1FGSA 3ZL8A 4KYQA 2A3KA 3EU0A 4NWFA 1ZCLA 2HY3A 1XM2A 2NT7A 2Y2FA 2CMCA 2AHSA 2I6OA 2ZMMA 2UUPA 2H4GA 5HDEA 2GC5A 1I57A 1P15A 5EHPA 4RH5A 1PYNA 2F6FA 2JJDA 5KA2A 2QDPA 1ECVA 2NTAA 2Y1OA 3QCHA 1PTYA 2YDUA 4GE6A 1R6HA 1I9SA 4GWFA 3ZM6A 4R0TA 1YTNA 2B4OA 5K25A 3D9CA 4OHEA 1ZC0A 2I6IA 2MBCA 5M43A 4NNDA 1T49A 2UAGA 1YFOA 2JFGA 5MMZB 1LQFA 1PA1A 2VEVA
chains in the Genus database with same CATH topology
3ZM1A 2I3RA 2OZ5A 4QAPA 3EMUA 4H34A 4ZN5A 2SHPA 3O4UA 2Y96A 1ZCKA 1YWFA 3V0JA 3BRHA 3S4EA 3AWEA 1Q6MA 2I4GA 3F41A 3LJ8A 4RDDA 1QXKA 1OHDA 2R0BA 4QUMA 4RKKA 2B3OA 3GXGA 2CNHA 3QCFA 3ZMPA 1ZZWA 4GRYA 4WOHA 3QCCA 2OUDA 3V0GA 3D1OA 3NMEA 2Q05A 2B4SA 3RGQA 1G7FA 1XBOA 2FH7A 1PXHA 3I80A 2CM7A 4OHDA 2BIJA 2PBNA 3S3KA 1OEUA 1YTWA 2QDCA 5KA7A 4OHIA 2H04A 5KA4A 5K9VA 1G1GA 1VHRA 3AWFA 1L8GA 5GTJA 2F70A 2CNGA 2QBSA 2CFVA 3QCJA 5BZXA 1U24A 1NWLA 3QCEA 2B07A 4MBBA 3O4SA 5KA0A 1YGUA 2CMBA 2CM8A 4RI5A 5IBSA 4RHGA 3QCDA 1OEMX 1WCHA 1GWZA 1OEOX 2B4UA 2HCMA 3QCBA 4JBCA 1A5YA 2I3UA 3EB1A 3QKQA 1EENA 2PSZA 2AZRA 1J4XA 1G1HA 3F9BA 2F6YA 2E0TA 5J8RA 3BM8A 1OESA 2FJNA 2I4EA 4HJPA 1BZHA 4GE5A 4RI4A 5KA3A 2CJZA 3ZM0A 2I6MA 5KA8A 5KA1A 2VEWA 2PT0A 2F6TA 1Q6NA 4D3RA 4D3QA 4DGXA 3H2XA 4GFVA 2F6WA 2CMAA 4NYHA 2BV5A 2F71A 2OC3A 2QBRA 2A8BA 2IMGA 4D3PA 2NT2A 4GE2A 2I42A 4JMJA 1WAXA 2P6XA 3RGOA 1X24A 1SUGA 3V0EA 4ERCA 1ONZA 5KAAA 2ZN7A 2CM3A 4QBWA 5K24A 1JF7A 3D42A 2I6JA 4WTYA 3O3LA 4PYHA 3CM3A 2VEYA 3U96A 3SMEA 1G4US 4ICZA 1Q6TA 4WU3A 3GXHA 1OEVA 4S0GA 2QBPA 1M3GA 5K22A 1ONYA 2G6ZA 4QUNA 2QBQA 3QCNA 4OHHA 3S3EA 1T4JA 5KABA 3B7OA 1C85A 3F9AA 1XXVA 2GJTA 5KADA 4BPCA 2J17A 2HNPA 3SR9A 2I5XA 2C7SA 2H4VA 4KYRA 1Q1MA 2QCJA 4TVVA 2NZ6A 5EHRA 4B04A 4Z6BA 1NL9A 1PA9A 2BZLA 1RXDA 4AZ1A 3MOWA 4R0SA 2I1YA 1JLNA 3QCGA 2H03A 1FQ1A 1FPRA 3V0HA 2J16A 3OMHA 3BLTA 3V0IA 1T48A 1EEOA 1G1FA 4HRFA 2J16B 1WRMA 2B49A 2WGPA 5AWXA 1BZJA 3QCIA 1YPTA 1L8KA 1U25A 3O5XA 3I36A 1XRIA 3D44A 2F6VA 2CNIA 1G4WR 4QBEA 4I8NA 5BUGA 5KACA 3RZ2A 5BX1A 2VEUA 3M4UA 2QDMA 1G7GA 5BZZA 2M3VA 4BJOA 4JNBA 5KA9A 2PA5A 2QEPA 4GFUA 1C86A 1OETA 3F99A 3A5KA 4NWGA 4Y2EA 1C88A 3D1HA 3OLRA 2C46A 1KAKA 2CM2A 2CNEA 4PVGA 1Q6PA 4WU2A 1YZ4A 3AWGA 1FPZA 4DGPA 3QCLA 4RH9A 3PS5A 3QCKA 4Y14A 5K9WA 1OHEA 1QZ0A 3A5JA 4YR8B 2PQ5A 3ZMQA 1XXPA 2G59A 2I6PA 2QCTA 3F81A 3S3HA 2GWOA 3CWEA 1PTUA 2F6ZA 2FJMA 1C83A 4ZRTA 2GP0A 5LXQB 3EAXA 1U26A 3QKPA 3MMJA 2B4PA 5IBMA 1PTVA 4QAHA 1YN9A 2VEXA 1YGRA 3V0DA 1Q6SA 2I4HA 1GFYA 4H1OA 3QCMA 4NX8A 1AAXA 1OHCA 2CNFA 1RPMA 2P4DA 4GRZA 2OOQA 4OHLA 2RF6A 3ZM3A 2HC1A 3RO1A 1C84A 1NZ7A 1D5RA 1C87A 1NNYA 1MKPA 3S4OA 2HC2A 3ZM2A 1LYVA 4JMKA 4ZI4A 2PI7A 1PTTA 3N0AA 2H4KA 3D1QA 2I75A 3V0FA 2DXPA 5K23A 4KI9A 1V3AA 3I7ZA 1I9TA 2F46A 4GS0A 2BGEA 3O4TA 4YAAA 1KAVA 2HVLA 1NO6A 1Q6JA 4R30A 1LARA 2HB1A 2Q47A 5I6VA 2NV5A 3BLUA 3ZV2A 4HJQA 2BGDA 2NLKA 2H02A 3S3FA 2ESBA 2HXPA 3EZZA 2HNQA 1NWEA 4J51A 1YTSA 1PH0A 4IKCA 3MOZA 1BZCA 4KYQA 2A3KA 3EU0A 4NWFA 1ZCLA 2HY3A 1XM2A 2NT7A 2Y2FA 2CMCA 2AHSA 2I6OA 2ZMMA 2H4GA 5HDEA 1I57A 1P15A 5EHPA 4RH5A 1PYNA 2F6FA 2JJDA 5KA2A 2QDPA 1ECVA 2NTAA 3QCHA 1PTYA 2YDUA 4GE6A 1R6HA 1I9SA 4GWFA 4R0TA 1YTNA 2B4OA 5K25A 3D9CA 4OHEA 1ZC0A 2I6IA 2MBCA 5M43A 4NNDA 1T49A 1YFOA 5MMZB 1LQFA 1PA1A 2VEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZM1 A;  2I3R A;  2OZ5 A;  4QAP A;  3EMU A;  4H34 A;  4ZN5 A;  2SHP A;  3O4U A;  2Y96 A;  1ZCK A;  1YWF A;  3V0J A;  3BRH A;  3S4E A;  3AWE A;  1Q6M A;  2I4G A;  3F41 A;  3LJ8 A;  4RDD A;  1QXK A;  1OHD A;  2R0B A;  4QUM A;  4RKK A;  2B3O A;  3GXG A;  2CNH A;  3QCF A;  3ZMP A;  1ZZW A;  4GRY A;  4WOH A;  3QCC A;  2OUD A;  3V0G A;  3D1O A;  3NME A;  2Q05 A;  2B4S A;  3RGQ A;  1G7F A;  1XBO A;  2FH7 A;  1PXH A;  3I80 A;  2CM7 A;  4OHD A;  2BIJ A;  2PBN A;  3S3K A;  1OEU A;  1YTW A;  2QDC A;  5KA7 A;  4OHI A;  2H04 A;  5KA4 A;  5K9V A;  1G1G A;  1VHR A;  3AWF A;  1L8G A;  5GTJ A;  2F70 A;  2CNG A;  2QBS A;  2CFV A;  3QCJ A;  5BZX A;  1U24 A;  1NWL A;  3QCE A;  2B07 A;  4MBB A;  3O4S A;  5KA0 A;  1YGU A;  2CMB A;  2CM8 A;  4RI5 A;  5IBS A;  4RHG A;  3QCD A;  1OEM X;  1WCH A;  1GWZ A;  1OEO X;  2B4U A;  2HCM A;  3QCB A;  4JBC A;  1A5Y A;  2I3U A;  3EB1 A;  3QKQ A;  1EEN A;  2PSZ A;  2AZR A;  1J4X A;  1G1H A;  3F9B A;  2F6Y A;  2E0T A;  5J8R A;  3BM8 A;  1OES A;  2FJN A;  2I4E A;  4HJP A;  1BZH A;  4GE5 A;  4RI4 A;  5KA3 A;  2CJZ A;  3ZM0 A;  2I6M A;  5KA8 A;  5KA1 A;  2VEW A;  2PT0 A;  2F6T A;  1Q6N A;  4D3R A;  4D3Q A;  4DGX A;  3H2X A;  4GFV A;  2F6W A;  2CMA A;  4NYH A;  2BV5 A;  2F71 A;  2OC3 A;  2QBR A;  2A8B A;  2IMG A;  4D3P A;  2NT2 A;  4GE2 A;  2I42 A;  4JMJ A;  1WAX A;  2P6X A;  3RGO A;  1X24 A;  1SUG A;  3V0E A;  4ERC A;  1ONZ A;  5KAA A;  2ZN7 A;  2CM3 A;  4QBW A;  5K24 A;  1JF7 A;  3D42 A;  2I6J A;  4WTY A;  3O3L A;  4PYH A;  3CM3 A;  2VEY A;  3U96 A;  3SME A;  1G4U S;  4ICZ A;  1Q6T A;  4WU3 A;  3GXH A;  1OEV A;  4S0G A;  2QBP A;  1M3G A;  5K22 A;  1ONY A;  2G6Z A;  4QUN A;  2QBQ A;  3QCN A;  4OHH A;  3S3E A;  1T4J A;  5KAB A;  3B7O A;  1C85 A;  3F9A A;  1XXV A;  2GJT A;  5KAD A;  4BPC A;  2J17 A;  2HNP A;  3SR9 A;  2I5X A;  2C7S A;  2H4V A;  4KYR A;  1Q1M A;  2QCJ A;  4TVV A;  2NZ6 A;  5EHR A;  4B04 A;  4Z6B A;  1NL9 A;  1PA9 A;  2BZL A;  1RXD A;  4AZ1 A;  3MOW A;  4R0S A;  2I1Y A;  1JLN A;  3QCG A;  2H03 A;  1FQ1 A;  1FPR A;  3V0H A;  2J16 A;  3OMH A;  3BLT A;  3V0I A;  1T48 A;  1EEO A;  1G1F A;  4HRF A;  2J16 B;  1WRM A;  2B49 A;  2WGP A;  5AWX A;  1BZJ A;  3QCI A;  1YPT A;  1L8K A;  1U25 A;  3O5X A;  3I36 A;  1XRI A;  3D44 A;  2F6V A;  2CNI A;  1G4W R;  4QBE A;  4I8N A;  5BUG A;  5KAC A;  3RZ2 A;  5BX1 A;  2VEU A;  3M4U A;  2QDM A;  1G7G A;  5BZZ A;  2M3V A;  4BJO A;  4JNB A;  5KA9 A;  2PA5 A;  2QEP A;  4GFU A;  1C86 A;  1OET A;  3F99 A;  3A5K A;  4NWG A;  4Y2E A;  1C88 A;  3D1H A;  3OLR A;  2C46 A;  1KAK A;  2CM2 A;  2CNE A;  4PVG A;  1Q6P A;  4WU2 A;  1YZ4 A;  3AWG A;  1FPZ A;  4DGP A;  3QCL A;  4RH9 A;  3PS5 A;  3QCK A;  4Y14 A;  5K9W A;  1OHE A;  1QZ0 A;  3A5J A;  4YR8 B;  2PQ5 A;  3ZMQ A;  1XXP A;  2G59 A;  2I6P A;  2QCT A;  3F81 A;  3S3H A;  2GWO A;  3CWE A;  1PTU A;  2F6Z A;  2FJM A;  1C83 A;  4ZRT A;  2GP0 A;  5LXQ B;  3EAX A;  1U26 A;  3QKP A;  3MMJ A;  2B4P A;  5IBM A;  1PTV A;  4QAH A;  1YN9 A;  2VEX A;  1YGR A;  3V0D A;  1Q6S A;  2I4H A;  1GFY A;  4H1O A;  3QCM A;  4NX8 A;  1AAX A;  1OHC A;  2CNF A;  1RPM A;  2P4D A;  4GRZ A;  2OOQ A;  4OHL A;  2RF6 A;  3ZM3 A;  2HC1 A;  3RO1 A;  1C84 A;  1NZ7 A;  1D5R A;  1C87 A;  1NNY A;  1MKP A;  3S4O A;  2HC2 A;  3ZM2 A;  1LYV A;  4JMK A;  4ZI4 A;  2PI7 A;  1PTT A;  3N0A A;  2H4K A;  3D1Q A;  2I75 A;  3V0F A;  2DXP A;  5K23 A;  4KI9 A;  1V3A A;  3I7Z A;  1I9T A;  2F46 A;  4GS0 A;  2BGE A;  3O4T A;  4YAA A;  1KAV A;  2HVL A;  1NO6 A;  1Q6J A;  4R30 A;  1LAR A;  2HB1 A;  2Q47 A;  5I6V A;  2NV5 A;  3BLU A;  3ZV2 A;  4HJQ A;  2BGD A;  2NLK A;  2H02 A;  3S3F A;  2ESB A;  2HXP A;  3EZZ A;  2HNQ A;  1NWE A;  4J51 A;  1YTS A;  1PH0 A;  4IKC A;  3MOZ A;  1BZC A;  4KYQ A;  2A3K A;  3EU0 A;  4NWF A;  1ZCL A;  2HY3 A;  1XM2 A;  2NT7 A;  2Y2F A;  2CMC A;  2AHS A;  2I6O A;  2ZMM A;  2H4G A;  5HDE A;  1I57 A;  1P15 A;  5EHP A;  4RH5 A;  1PYN A;  2F6F A;  2JJD A;  5KA2 A;  2QDP A;  1ECV A;  2NTA A;  3QCH A;  1PTY A;  2YDU A;  4GE6 A;  1R6H A;  1I9S A;  4GWF A;  4R0T A;  1YTN A;  2B4O A;  5K25 A;  3D9C A;  4OHE A;  1ZC0 A;  2I6I A;  2MBC A;  5M43 A;  4NND A;  1T49 A;  1YFO A;  5MMZ B;  1LQF A;  1PA1 A;  2VEV A; 
#chains in the Genus database with same CATH topology
 3ZM1 A;  2I3R A;  2OZ5 A;  4QAP A;  3EMU A;  4H34 A;  4ZN5 A;  2SHP A;  3O4U A;  2Y96 A;  1ZCK A;  2WJP A;  1YWF A;  3V0J A;  3BRH A;  3S4E A;  3AWE A;  1Q6M A;  1O5Z A;  2I4G A;  1W7K A;  3F41 A;  3LJ8 A;  4RDD A;  1QXK A;  1OHD A;  2R0B A;  4QUM A;  4UAG A;  4RKK A;  2B3O A;  3GXG A;  2CNH A;  3QCF A;  3ZMP A;  1ZZW A;  4GRY A;  4CVL A;  4WOH A;  3QCC A;  2OUD A;  3V0G A;  2UUO A;  3D1O A;  3NME A;  2Q05 A;  2B4S A;  3RGQ A;  1G7F A;  1XBO A;  2FH7 A;  1PXH A;  3I80 A;  2CM7 A;  4OHD A;  2BIJ A;  3LK7 A;  2AM1 A;  2PBN A;  3S3K A;  1OEU A;  1YTW A;  2QDC A;  5KA7 A;  5A5E A;  4OHI A;  2H04 A;  5KA4 A;  5K9V A;  1G1G A;  1VHR A;  3AWF A;  1L8G A;  5GTJ A;  2F70 A;  2CNG A;  2QBS A;  2AM2 A;  2CFV A;  3QCJ A;  5BZX A;  1U24 A;  4CVK A;  1NWL A;  3QCE A;  2B07 A;  4MBB A;  3O4S A;  5KA0 A;  1YGU A;  2CMB A;  2CM8 A;  4RI5 A;  5IBS A;  1JBW A;  4RHG A;  3QCD A;  1OEM X;  1WCH A;  1GWZ A;  1OEO X;  2B4U A;  2HCM A;  2WTZ A;  3QCB A;  4JBC A;  1A5Y A;  2I3U A;  1UAG A;  3EB1 A;  3QKQ A;  1EEN A;  2PSZ A;  2AZR A;  3PYZ A;  1J4X A;  1G1H A;  3F9B A;  2F6Y A;  2E0T A;  5J8R A;  1E8C A;  3BM8 A;  1OES A;  2FJN A;  2I4E A;  4HJP A;  1BZH A;  4GE5 A;  4RI4 A;  5KA3 A;  2CJZ A;  3ZM0 A;  2I6M A;  5KA8 A;  5KA1 A;  2VEW A;  2PT0 A;  2F6T A;  1Q6N A;  1W78 A;  4D3R A;  4D3Q A;  4DGX A;  2Y68 A;  3H2X A;  4GFV A;  2F6W A;  2CMA A;  4HV4 A;  4NYH A;  2BV5 A;  2F71 A;  1E0D A;  2OC3 A;  2QBR A;  2A8B A;  2IMG A;  4D3P A;  2NT2 A;  4GE2 A;  2I42 A;  4JMJ A;  1WAX A;  2P6X A;  3RGO A;  1X24 A;  1SUG A;  3V0E A;  4ERC A;  1ONZ A;  5KAA A;  2ZN7 A;  2CM3 A;  4QBW A;  1J6U A;  2VOS A;  5K24 A;  1JF7 A;  3D42 A;  2I6J A;  4WTY A;  3UAG A;  3O3L A;  4PYH A;  3CM3 A;  2VEY A;  2F00 A;  5A5F A;  3U96 A;  3SME A;  4C12 A;  1G4U S;  1P31 A;  4ICZ A;  1Q6T A;  4WU3 A;  3GXH A;  1OEV A;  4S0G A;  2QBP A;  1M3G A;  5K22 A;  1ONY A;  2G6Z A;  4QUN A;  2QBQ A;  3QCN A;  4OHH A;  3S3E A;  1T4J A;  5KAB A;  3B7O A;  1C85 A;  3F9A A;  1XXV A;  2GJT A;  5KAD A;  4BPC A;  2J17 A;  2HNP A;  3SR9 A;  2I5X A;  2C7S A;  4BUC A;  2H4V A;  4KYR A;  1Q1M A;  2QCJ A;  4TVV A;  2NZ6 A;  5EHR A;  4B04 A;  4Z6B A;  1NL9 A;  1PA9 A;  2BZL A;  1RXD A;  4AZ1 A;  3MOW A;  4R0S A;  2I1Y A;  1JLN A;  3QCG A;  2H03 A;  1FQ1 A;  1FPR A;  3V0H A;  2J16 A;  2GCB A;  3OMH A;  4ZIY A;  3BLT A;  3V0I A;  1T48 A;  1EEO A;  1G1F A;  4HRF A;  2J16 B;  1WRM A;  2B49 A;  2WGP A;  2VTD A;  5AWX A;  1BZJ A;  3QCI A;  1YPT A;  1L8K A;  1U25 A;  3O5X A;  3I36 A;  1XRI A;  3D44 A;  2F6V A;  2CNI A;  4CVM A;  1G4W R;  1EEH A;  4QBE A;  4I8N A;  1GQY A;  5BUG A;  5KAC A;  3RZ2 A;  2GC6 A;  5BX1 A;  2VEU A;  3M4U A;  2QDM A;  1G7G A;  2JFH A;  5BZZ A;  2M3V A;  4BJO A;  4C13 A;  4JNB A;  5KA9 A;  2PA5 A;  2QEP A;  2VTE A;  4GFU A;  2XJA A;  1C86 A;  2Y66 A;  1OET A;  3F99 A;  3A5K A;  4NWG A;  4Y2E A;  2JFF A;  1C88 A;  2GCA A;  3D1H A;  3OLR A;  2C46 A;  1KAK A;  2CM2 A;  2CNE A;  4PVG A;  1Q6P A;  4WU2 A;  1YZ4 A;  3AWG A;  1FPZ A;  4DGP A;  3QCL A;  4RH9 A;  3PS5 A;  3QCK A;  4Y14 A;  5K9W A;  1OHE A;  1QZ0 A;  3A5J A;  4YR8 B;  2PQ5 A;  3ZMQ A;  1XXP A;  2G59 A;  3NRS A;  2I6P A;  2QCT A;  1P3D A;  3N2A A;  3F81 A;  3S3H A;  2GWO A;  3CWE A;  1PTU A;  2F6Z A;  1GG4 A;  2FJM A;  1C83 A;  4ZRT A;  2XPC A;  2GP0 A;  5LXQ B;  3EAX A;  1U26 A;  3QKP A;  3MMJ A;  2B4P A;  5IBM A;  1PTV A;  4QAH A;  1YN9 A;  2VEX A;  1YGR A;  3V0D A;  1Q6S A;  2I4H A;  1GFY A;  4H1O A;  3QCM A;  4NX8 A;  1GQQ A;  1AAX A;  3QCZ A;  1OHC A;  2CNF A;  1RPM A;  2P4D A;  4GRZ A;  3HN7 A;  2OOQ A;  4OHL A;  2RF6 A;  3ZM3 A;  2HC1 A;  3RO1 A;  1C84 A;  1NZ7 A;  1D5R A;  1C87 A;  1NNY A;  2Y67 A;  1MKP A;  3S4O A;  2HC2 A;  3ZM2 A;  1LYV A;  4JMK A;  4QF5 A;  4ZI4 A;  2PI7 A;  1PTT A;  3N0A A;  2H4K A;  3D1Q A;  2I75 A;  2VOR A;  3V0F A;  3MVN A;  2DXP A;  5K23 A;  4KI9 A;  1V3A A;  3I7Z A;  1I9T A;  2F46 A;  4GS0 A;  2BGE A;  3O4T A;  4YAA A;  4BUB A;  1JBV A;  1KAV A;  2HVL A;  1NO6 A;  1Q6J A;  4R30 A;  1LAR A;  2HB1 A;  2Q47 A;  5I6V A;  2NV5 A;  3BLU A;  3ZV2 A;  4HJQ A;  4QDI A;  2BGD A;  2X5O A;  2NLK A;  2H02 A;  3S3F A;  2ESB A;  2HXP A;  3EZZ A;  2HNQ A;  1NWE A;  4J51 A;  1YTS A;  1PH0 A;  3ZM5 A;  4IKC A;  3MOZ A;  1BZC A;  1FGS A;  3ZL8 A;  4KYQ A;  2A3K A;  3EU0 A;  4NWF A;  1ZCL A;  2HY3 A;  1XM2 A;  2NT7 A;  2Y2F A;  2CMC A;  2AHS A;  2I6O A;  2ZMM A;  2UUP A;  2H4G A;  5HDE A;  2GC5 A;  1I57 A;  1P15 A;  5EHP A;  4RH5 A;  1PYN A;  2F6F A;  2JJD A;  5KA2 A;  2QDP A;  1ECV A;  2NTA A;  2Y1O A;  3QCH A;  1PTY A;  2YDU A;  4GE6 A;  1R6H A;  1I9S A;  4GWF A;  3ZM6 A;  4R0T A;  1YTN A;  2B4O A;  5K25 A;  3D9C A;  4OHE A;  1ZC0 A;  2I6I A;  2MBC A;  5M43 A;  4NND A;  1T49 A;  2UAG A;  1YFO A;  2JFG A;  5MMZ B;  1LQF A;  1PA1 A;  2VEV A; 
#chains in the Genus database with same CATH homology
 3ZM1 A;  2I3R A;  2OZ5 A;  4QAP A;  3EMU A;  4H34 A;  4ZN5 A;  2SHP A;  3O4U A;  2Y96 A;  1ZCK A;  1YWF A;  3V0J A;  3BRH A;  3S4E A;  3AWE A;  1Q6M A;  2I4G A;  3F41 A;  3LJ8 A;  4RDD A;  1QXK A;  1OHD A;  2R0B A;  4QUM A;  4RKK A;  2B3O A;  3GXG A;  2CNH A;  3QCF A;  3ZMP A;  1ZZW A;  4GRY A;  4WOH A;  3QCC A;  2OUD A;  3V0G A;  3D1O A;  3NME A;  2Q05 A;  2B4S A;  3RGQ A;  1G7F A;  1XBO A;  2FH7 A;  1PXH A;  3I80 A;  2CM7 A;  4OHD A;  2BIJ A;  2PBN A;  3S3K A;  1OEU A;  1YTW A;  2QDC A;  5KA7 A;  4OHI A;  2H04 A;  5KA4 A;  5K9V A;  1G1G A;  1VHR A;  3AWF A;  1L8G A;  5GTJ A;  2F70 A;  2CNG A;  2QBS A;  2CFV A;  3QCJ A;  5BZX A;  1U24 A;  1NWL A;  3QCE A;  2B07 A;  4MBB A;  3O4S A;  5KA0 A;  1YGU A;  2CMB A;  2CM8 A;  4RI5 A;  5IBS A;  4RHG A;  3QCD A;  1OEM X;  1WCH A;  1GWZ A;  1OEO X;  2B4U A;  2HCM A;  3QCB A;  4JBC A;  1A5Y A;  2I3U A;  3EB1 A;  3QKQ A;  1EEN A;  2PSZ A;  2AZR A;  1J4X A;  1G1H A;  3F9B A;  2F6Y A;  2E0T A;  5J8R A;  3BM8 A;  1OES A;  2FJN A;  2I4E A;  4HJP A;  1BZH A;  4GE5 A;  4RI4 A;  5KA3 A;  2CJZ A;  3ZM0 A;  2I6M A;  5KA8 A;  5KA1 A;  2VEW A;  2PT0 A;  2F6T A;  1Q6N A;  4D3R A;  4D3Q A;  4DGX A;  3H2X A;  4GFV A;  2F6W A;  2CMA A;  4NYH A;  2BV5 A;  2F71 A;  2OC3 A;  2QBR A;  2A8B A;  2IMG A;  4D3P A;  2NT2 A;  4GE2 A;  2I42 A;  4JMJ A;  1WAX A;  2P6X A;  3RGO A;  1X24 A;  1SUG A;  3V0E A;  4ERC A;  1ONZ A;  5KAA A;  2ZN7 A;  2CM3 A;  4QBW A;  5K24 A;  1JF7 A;  3D42 A;  2I6J A;  4WTY A;  3O3L A;  4PYH A;  3CM3 A;  2VEY A;  3U96 A;  3SME A;  1G4U S;  4ICZ A;  1Q6T A;  4WU3 A;  3GXH A;  1OEV A;  4S0G A;  2QBP A;  1M3G A;  5K22 A;  1ONY A;  2G6Z A;  4QUN A;  2QBQ A;  3QCN A;  4OHH A;  3S3E A;  1T4J A;  5KAB A;  3B7O A;  1C85 A;  3F9A A;  1XXV A;  2GJT A;  5KAD A;  4BPC A;  2J17 A;  2HNP A;  3SR9 A;  2I5X A;  2C7S A;  2H4V A;  4KYR A;  1Q1M A;  2QCJ A;  4TVV A;  2NZ6 A;  5EHR A;  4B04 A;  4Z6B A;  1NL9 A;  1PA9 A;  2BZL A;  1RXD A;  4AZ1 A;  3MOW A;  4R0S A;  2I1Y A;  1JLN A;  3QCG A;  2H03 A;  1FQ1 A;  1FPR A;  3V0H A;  2J16 A;  3OMH A;  3BLT A;  3V0I A;  1T48 A;  1EEO A;  1G1F A;  4HRF A;  2J16 B;  1WRM A;  2B49 A;  2WGP A;  5AWX A;  1BZJ A;  3QCI A;  1YPT A;  1L8K A;  1U25 A;  3O5X A;  3I36 A;  1XRI A;  3D44 A;  2F6V A;  2CNI A;  1G4W R;  4QBE A;  4I8N A;  5BUG A;  5KAC A;  3RZ2 A;  5BX1 A;  2VEU A;  3M4U A;  2QDM A;  1G7G A;  5BZZ A;  2M3V A;  4BJO A;  4JNB A;  5KA9 A;  2PA5 A;  2QEP A;  4GFU A;  1C86 A;  1OET A;  3F99 A;  3A5K A;  4NWG A;  4Y2E A;  1C88 A;  3D1H A;  3OLR A;  2C46 A;  1KAK A;  2CM2 A;  2CNE A;  4PVG A;  1Q6P A;  4WU2 A;  1YZ4 A;  3AWG A;  1FPZ A;  4DGP A;  3QCL A;  4RH9 A;  3PS5 A;  3QCK A;  4Y14 A;  5K9W A;  1OHE A;  1QZ0 A;  3A5J A;  4YR8 B;  2PQ5 A;  3ZMQ A;  1XXP A;  2G59 A;  2I6P A;  2QCT A;  3F81 A;  3S3H A;  2GWO A;  3CWE A;  1PTU A;  2F6Z A;  2FJM A;  1C83 A;  4ZRT A;  2GP0 A;  5LXQ B;  3EAX A;  1U26 A;  3QKP A;  3MMJ A;  2B4P A;  5IBM A;  1PTV A;  4QAH A;  1YN9 A;  2VEX A;  1YGR A;  3V0D A;  1Q6S A;  2I4H A;  1GFY A;  4H1O A;  3QCM A;  4NX8 A;  1AAX A;  1OHC A;  2CNF A;  1RPM A;  2P4D A;  4GRZ A;  2OOQ A;  4OHL A;  2RF6 A;  3ZM3 A;  2HC1 A;  3RO1 A;  1C84 A;  1NZ7 A;  1D5R A;  1C87 A;  1NNY A;  1MKP A;  3S4O A;  2HC2 A;  3ZM2 A;  1LYV A;  4JMK A;  4ZI4 A;  2PI7 A;  1PTT A;  3N0A A;  2H4K A;  3D1Q A;  2I75 A;  3V0F A;  2DXP A;  5K23 A;  4KI9 A;  1V3A A;  3I7Z A;  1I9T A;  2F46 A;  4GS0 A;  2BGE A;  3O4T A;  4YAA A;  1KAV A;  2HVL A;  1NO6 A;  1Q6J A;  4R30 A;  1LAR A;  2HB1 A;  2Q47 A;  5I6V A;  2NV5 A;  3BLU A;  3ZV2 A;  4HJQ A;  2BGD A;  2NLK A;  2H02 A;  3S3F A;  2ESB A;  2HXP A;  3EZZ A;  2HNQ A;  1NWE A;  4J51 A;  1YTS A;  1PH0 A;  4IKC A;  3MOZ A;  1BZC A;  4KYQ A;  2A3K A;  3EU0 A;  4NWF A;  1ZCL A;  2HY3 A;  1XM2 A;  2NT7 A;  2Y2F A;  2CMC A;  2AHS A;  2I6O A;  2ZMM A;  2H4G A;  5HDE A;  1I57 A;  1P15 A;  5EHP A;  4RH5 A;  1PYN A;  2F6F A;  2JJD A;  5KA2 A;  2QDP A;  1ECV A;  2NTA A;  3QCH A;  1PTY A;  2YDU A;  4GE6 A;  1R6H A;  1I9S A;  4GWF A;  4R0T A;  1YTN A;  2B4O A;  5K25 A;  3D9C A;  4OHE A;  1ZC0 A;  2I6I A;  2MBC A;  5M43 A;  4NND A;  1T49 A;  1YFO A;  5MMZ B;  1LQF A;  1PA1 A;  2VEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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