4REXA

Crystal structure of the first ww domain of human yap2 isoform
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
48
structure length
48
Chain Sequence
GAMGFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the first WW domain of human YAP2 isoform.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Yorkie homolog
total genus 8
structure length 48
sequence length 48
ec nomenclature
pdb deposition date 2014-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00397 WW WW domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.70.10 Mainly Beta Single Sheet Ubiquitin Ligase Nedd4; Chain: W; Ubiquitin Ligase Nedd4; Chain: W; 4rexA00
2ZQSA 3KCEA 2XP7A 3KAHA 2ZR6A 3M85A 2JV4A 2ITKA 4REXA 3LE4A 3KAGA 3L4HA 2L4JA 2ZR4A 2XPBA 1TK7A 1WMVA 2YSHA 2BA1A 2ZQUA 5AHTA 4U84A 3ODKA 2F21A 3TCZA 2JMFA 1YW5A 1ZCNA 3NTPA 2XP4A 2ZQVA 1O6WA 4U86A 1WR7A 3KAFA 2YSFA 2M8JA 4QIBA 4U85A 2ZR5A 2XP8A 2LAJA 2YSBA 2DK1A 2MDIA 2DMVA 4E5RA 2E45A 2Q5AA 1I5HW 3KABA 2YSIA 5CQ2A 2ZQTA 3KAIA 1K9RA 2DJYA 1F8AB 2EZ5W 3CNGA 2ZAJA 2RE3A 3KADA 2XPAA 2JXWA 1PINA 2M8IA 2DK7A 2XP3A 1K9QA 2YSGA 3M7NA 2XP9A 1JMQA 3TDBA 2KXQA 3OOBA 1EG3A 2XP5A 3TC5A 1NMVA 2DWVA 1EG4A 2XP6A 2M3OW 3WH0A 2JX8A
chains in the Genus database with same CATH superfamily
2Y8NB 4GLXA 2ZQSA 3KCEA 2XP7A 1FLCA 3KAHA 3FSBA 2ZR6A 3MQHA 3M85A 2JV4A 2ITKA 4REXA 3LE4A 3KAGA 3L4HA 2L4JA 2ZR4A 2QRVA 2XPBA 1TK7A 1WMVA 2YSHA 2BA1A 2ZQUA 5AHTA 4U84A 5E66A 3MQGA 3ODKA 4A0TA 5E62A 2F21A 3TCZA 2JMFA 1YW5A 5U47A 1ZCNA 3PQHA 3NTPA 1RP5A 2XP4A 1TR8A 2ZQVA 1O6WA 4U86A 1WR7A 3KAFA 2YSFA 2M8JA 4QIBA 4U85A 2ZR5A 2XP8A 2LAJA 2YSBA 2DK1A 2MDIA 2DMVA 4E5RA 3LKXB 2YAJB 2E45A 2OWOA 2Q5AA 1I5HW 3KABA 5E64A 2YSIA 5CQ2A 3FS8A 5E5WA 2ZQTA 3KAIA 1K9RA 2DJYA 3FSCA 1F8AB 2EZ5W 3CNGA 2ZAJA 2WADA 2RE3A 3KADA 3MCBB 3LKXA 2XPAA 2JXWA 1PINA 2M8IA 2WAEA 2DK7A 2XP3A 1K9QA 2YSGA 3M7NA 2XP9A 1JMQA 3TDBA 2KXQA 5E65A 3OOBA 3MCBA 1EG3A 2XP5A 3TC5A 1NMVA 4A0UA 1EG4A 2DWVA 2XP6A 2M3OW 3WH0A 2JX8A
chains in the Genus database with same CATH topology
2Y8NB 4GLXA 2ZQSA 3KCEA 2XP7A 1FLCA 3KAHA 3FSBA 2ZR6A 3MQHA 3M85A 2JV4A 2ITKA 4REXA 3LE4A 3KAGA 3L4HA 2L4JA 2ZR4A 2QRVA 2XPBA 1TK7A 1WMVA 2YSHA 2BA1A 2ZQUA 5AHTA 4U84A 5E66A 3MQGA 3ODKA 4A0TA 5E62A 2F21A 3TCZA 2JMFA 1YW5A 5U47A 1ZCNA 3PQHA 3NTPA 1RP5A 2XP4A 1TR8A 2ZQVA 1O6WA 4U86A 1WR7A 3KAFA 2YSFA 2M8JA 4QIBA 4U85A 2ZR5A 2XP8A 2LAJA 2YSBA 2DK1A 2MDIA 2DMVA 4E5RA 3LKXB 2YAJB 2E45A 2OWOA 2Q5AA 1I5HW 3KABA 5E64A 2YSIA 5CQ2A 3FS8A 5E5WA 2ZQTA 3KAIA 1K9RA 2DJYA 3FSCA 1F8AB 2EZ5W 3CNGA 2ZAJA 2WADA 2RE3A 3KADA 3MCBB 3LKXA 2XPAA 2JXWA 1PINA 2M8IA 2WAEA 2DK7A 2XP3A 1K9QA 2YSGA 3M7NA 2XP9A 1JMQA 3TDBA 2KXQA 5E65A 3OOBA 3MCBA 1EG3A 2XP5A 3TC5A 1NMVA 4A0UA 1EG4A 2DWVA 2XP6A 2M3OW 3WH0A 2JX8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZQS A;  3KCE A;  2XP7 A;  3KAH A;  2ZR6 A;  3M85 A;  2JV4 A;  2ITK A;  4REX A;  3LE4 A;  3KAG A;  3L4H A;  2L4J A;  2ZR4 A;  2XPB A;  1TK7 A;  1WMV A;  2YSH A;  2BA1 A;  2ZQU A;  5AHT A;  4U84 A;  3ODK A;  2F21 A;  3TCZ A;  2JMF A;  1YW5 A;  1ZCN A;  3NTP A;  2XP4 A;  2ZQV A;  1O6W A;  4U86 A;  1WR7 A;  3KAF A;  2YSF A;  2M8J A;  4QIB A;  4U85 A;  2ZR5 A;  2XP8 A;  2LAJ A;  2YSB A;  2DK1 A;  2MDI A;  2DMV A;  4E5R A;  2E45 A;  2Q5A A;  1I5H W;  3KAB A;  2YSI A;  5CQ2 A;  2ZQT A;  3KAI A;  1K9R A;  2DJY A;  1F8A B;  2EZ5 W;  3CNG A;  2ZAJ A;  2RE3 A;  3KAD A;  2XPA A;  2JXW A;  1PIN A;  2M8I A;  2DK7 A;  2XP3 A;  1K9Q A;  2YSG A;  3M7N A;  2XP9 A;  1JMQ A;  3TDB A;  2KXQ A;  3OOB A;  1EG3 A;  2XP5 A;  3TC5 A;  1NMV A;  2DWV A;  1EG4 A;  2XP6 A;  2M3O W;  3WH0 A;  2JX8 A; 
#chains in the Genus database with same CATH topology
 2Y8N B;  4GLX A;  2ZQS A;  3KCE A;  2XP7 A;  1FLC A;  3KAH A;  3FSB A;  2ZR6 A;  3MQH A;  3M85 A;  2JV4 A;  2ITK A;  4REX A;  3LE4 A;  3KAG A;  3L4H A;  2L4J A;  2ZR4 A;  2QRV A;  2XPB A;  1TK7 A;  1WMV A;  2YSH A;  2BA1 A;  2ZQU A;  5AHT A;  4U84 A;  5E66 A;  3MQG A;  3ODK A;  4A0T A;  5E62 A;  2F21 A;  3TCZ A;  2JMF A;  1YW5 A;  5U47 A;  1ZCN A;  3PQH A;  3NTP A;  1RP5 A;  2XP4 A;  1TR8 A;  2ZQV A;  1O6W A;  4U86 A;  1WR7 A;  3KAF A;  2YSF A;  2M8J A;  4QIB A;  4U85 A;  2ZR5 A;  2XP8 A;  2LAJ A;  2YSB A;  2DK1 A;  2MDI A;  2DMV A;  4E5R A;  3LKX B;  2YAJ B;  2E45 A;  2OWO A;  2Q5A A;  1I5H W;  3KAB A;  5E64 A;  2YSI A;  5CQ2 A;  3FS8 A;  5E5W A;  2ZQT A;  3KAI A;  1K9R A;  2DJY A;  3FSC A;  1F8A B;  2EZ5 W;  3CNG A;  2ZAJ A;  2WAD A;  2RE3 A;  3KAD A;  3MCB B;  3LKX A;  2XPA A;  2JXW A;  1PIN A;  2M8I A;  2WAE A;  2DK7 A;  2XP3 A;  1K9Q A;  2YSG A;  3M7N A;  2XP9 A;  1JMQ A;  3TDB A;  2KXQ A;  5E65 A;  3OOB A;  3MCB A;  1EG3 A;  2XP5 A;  3TC5 A;  1NMV A;  4A0U A;  1EG4 A;  2DWV A;  2XP6 A;  2M3O W;  3WH0 A;  2JX8 A; 
#chains in the Genus database with same CATH homology
 2Y8N B;  4GLX A;  2ZQS A;  3KCE A;  2XP7 A;  1FLC A;  3KAH A;  3FSB A;  2ZR6 A;  3MQH A;  3M85 A;  2JV4 A;  2ITK A;  4REX A;  3LE4 A;  3KAG A;  3L4H A;  2L4J A;  2ZR4 A;  2QRV A;  2XPB A;  1TK7 A;  1WMV A;  2YSH A;  2BA1 A;  2ZQU A;  5AHT A;  4U84 A;  5E66 A;  3MQG A;  3ODK A;  4A0T A;  5E62 A;  2F21 A;  3TCZ A;  2JMF A;  1YW5 A;  5U47 A;  1ZCN A;  3PQH A;  3NTP A;  1RP5 A;  2XP4 A;  1TR8 A;  2ZQV A;  1O6W A;  4U86 A;  1WR7 A;  3KAF A;  2YSF A;  2M8J A;  4QIB A;  4U85 A;  2ZR5 A;  2XP8 A;  2LAJ A;  2YSB A;  2DK1 A;  2MDI A;  2DMV A;  4E5R A;  3LKX B;  2YAJ B;  2E45 A;  2OWO A;  2Q5A A;  1I5H W;  3KAB A;  5E64 A;  2YSI A;  5CQ2 A;  3FS8 A;  5E5W A;  2ZQT A;  3KAI A;  1K9R A;  2DJY A;  3FSC A;  1F8A B;  2EZ5 W;  3CNG A;  2ZAJ A;  2WAD A;  2RE3 A;  3KAD A;  3MCB B;  3LKX A;  2XPA A;  2JXW A;  1PIN A;  2M8I A;  2WAE A;  2DK7 A;  2XP3 A;  1K9Q A;  2YSG A;  3M7N A;  2XP9 A;  1JMQ A;  3TDB A;  2KXQ A;  5E65 A;  3OOB A;  3MCB A;  1EG3 A;  2XP5 A;  3TC5 A;  1NMV A;  4A0U A;  1EG4 A;  2DWV A;  2XP6 A;  2M3O W;  3WH0 A;  2JX8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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