4RGCA

277k crystal structure of escherichia coli dihydrofolate reductase
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
159
structure length
158
Chain Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYFEILERR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-resolution X-ray crystallography.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords Dihydrofolate reductase
total genus 47
structure length 158
sequence length 159
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2014-09-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 4rgcA00
3IA4A 4NX6A 1RX4A 1PD9A 5HI6A 1RC4A 4P66A 3QLYA 1IA1A 2ZZAA 2HM9A 1RD7A 4QHVA 5HQZA 3QGTA 1QZFA 5ECXA 2ITHA 4LAHX 1DRAA 1RA3A 1HFPA 2FZJA 3FRFX 3NRRA 1RX8A 1DR2A 3D84X 3SGYA 3D80A 1JUVA 3SA2A 3CD2A 1J3KA 3K47A 1CD2A 3DATA 1DYHA 4DPHA 4M6LA 3SRUX 1DYJA 1DR6A 4X5IA 2LF1A 1LY4A 2JYBA 4P3QA 3EEMA 3SRWX 4OR7A 3EEJA 3NU0A 3QYOA 3TQ9A 3KFYA 3F8ZA 3QL0A 4EJ1A 3QYLA 4ELHA 3RG9A 4X5HA 5JG0X 4HA7A 1BOZA 3NZ6X 5HT4A 4ELEA 4IXFX 1RG7A 3FQVA 3S9UA 3FRDX 3UM5A 1DAJA 2ANQA 3KJSA 3GHVA 3EEKA 1DDSA 3INVA 3F0QX 1RX2A 3CLBA 1DISA 3S7AA 3QG2A 3OAFA 1DF7A 5ECCA 1DIUA 3K74A 1U71A 1ZDRA 1DHIA 1JOMA 3I3RA 3DL5A 4M2XA 2W3MA 5HVBA 1RX7A 3FL8A 1RF7A 3SR5X 3DG8A 3IX9A 3KJRA 4FGHA 3IRNA 1DDRA 3JWFA 4QJZD 6DFRA 5HT5A 5HVEA 4XT7A 1RA9A 4QI9A 3ROAA 4DDRA 3M09A 4CD2A 4XT8A 4M7UA 3ZPGA 3NTZA 2QK8A 1BZFA 3F0UX 5HPBA 1DHJA 5HF2X 1MVTA 2OBCA 3RO9A 3FQOA 1CZ3A 3F0XX 3NZBX 1J3IA 2INQA 4KBNA 3NZDA 1DG7A 4XT5A 4XT6A 1RB2A 3JTWA 1S3WA 3SRQX 1DYIA 4PDJA 1M78A 3GI2A 2KGKA 2C2TA 4GH8A 1PD8A 2W3BA 4G95A 5DXVA 4XE6X 1DRHA 3TQAA 3IROA 3QLSA 2BL9A 3CSEA 1RX1A 1U70A 3F91A 4ELGA 2GD9A 3VCOA 2W9TA 3JW3A 3FQFA 4I1NA 3IRMA 3NZCX 2G6VA 1RX3A 2BLBA 3FYVX 4XECX 2B3ZA 4RGCA 3EIGA 1RH3A 3SA1A 3M08A 4Q0DA 1RE7A 1VDRA 1DLRA 4KJJA 4KJKA 1RX6A 3LG4A 5CCCA 1S3YA 4Q0EA 3NXOA 4KYAA 4HOEA 4KY8A 3DGAA 4I13A 5HF0X 1OHJA 2FZIA 3DFRA 4OSGA 4QJCA 4EILA 1VJ3A 3F0VX 2P4GA 3FQZA 1RA2A 2ANOA 3DAUA 2C2SA 4H95A 3FL9A 3QLWA 3FYWX 1IA4A 1DR4A 3KY8A 4P3RA 5E8QA 1DR5A 4NX7A 3SAIA 4TU5X 4LAGX 1RX9A 1U72A 3FQ0A 5EAJA 3TQ8A 4M6JA 4ELBA 4M6KA 2W9HA 5U26A 4DPDA 1RA8A 4FGGA 1KMVA 3NXRA 4KM0A 1LY3A 4QLGA 4PSSA 3N0HA 5FDAA 1AO8A 3EX8A 3CL9A 3F0SX 3NXXA 1IA2A 4FHBA 2BLAA 4KNEA 4PTJA 3QLZA 4DP3A 3QFXA 3JVXA 3EELA 5HUIA 4XRBA 3GHCA 1DR7A 4G3MA 4KFJA 3K2HA 1M79A 3JWCA 4KD7A 3FRAX 5DFRA 1M7AA 2XW7A 4P68A 1DR1A 2AZNA 4HOGA 4H97A 4PSTA 1DG8A 4DFRA 2W9GA 3Q1HA 1PDBA 4KEBA 1KLKA 4Q67A 3FQCA 3FRBX 5HSRA 4PSYA 4EIZA 3DRCA 1YHOA 2L28A 3DL6A 2W3WA 3NXTA 2HXVA 1J3JA 2O7PA 2D0KA 1LUDA 1AI9A 1E26A 2OIPA 1DHFA 4IXGX 1RA1A 4QLFA 5HSUA 1MVSA 8DFRA 1S3UA 1JOLA 2CD2A 4XT4A 3UM8A 1RX5A 4IXED 4X5JA 3QL3A 3HBBA 3NZ9X 3F8YA 3NZAX 4ELFA 3JWKA 4ECKA 4EIGA 4HA9A 4H96A 4G8ZX 2FZHA 3SQYX 3E0BA 4KAKA 1RB3A 4LAEX 5U27A 5HQYA 4PTHA 1DLSA 2DRCA 2DHFA 4KY4A 3IA5A 4KLXA 1AOEA 2W3VA 2D5NA 4KJLA 3HJ3A 4KM2A 1DR3A 1DG5A 1DRBA 1DYRA 3OCHA 3TQBA 2CIGA 2BLCA 4Q6AA 3SRSX 1SEJA 3JSUA 4X5GA 1HFRA 3UM6A 4QLEA 3I8AX 3FREX 3NXYA 1DREA 4X5FA 1DRFA 2W9SA 3JWMA 3NXVA 1OHKA 3ZPCA 1S3VA 3F0BX 1TDRA 3FY9X 3QLRA 3FS6A 1IA3A 4H98A 2H2QA 4M7VA 7DFRA 4KL9A 1HFQA 3SRRX 4HOFA 5CC9A 3QLXA 1KMSA 3S3VA 3R33A 3FY8X 2HQPA 2W3AA 3GHWA 3JW5A 3K45A 1D1GA 3L3RA 3KGYA 4LEKX 5JA3A 3GYFA 3SH2A 3TD8A
chains in the Genus database with same CATH superfamily
3IA4A 4NX6A 1RX4A 1PD9A 5HI6A 1RC4A 4P66A 3QLYA 1IA1A 2ZZAA 2HM9A 1RD7A 4QHVA 5HQZA 3QGTA 1QZFA 5ECXA 2ITHA 4LAHX 1DRAA 1RA3A 1HFPA 2FZJA 3FRFX 3NRRA 1RX8A 1DR2A 3D84X 3SGYA 3D80A 1JUVA 3SA2A 3CD2A 1J3KA 3K47A 1CD2A 3DATA 1DYHA 4DPHA 4M6LA 3SRUX 1DYJA 1DR6A 4X5IA 2LF1A 1LY4A 2JYBA 4P3QA 3EEMA 3SRWX 4OR7A 3EEJA 3NU0A 3QYOA 3TQ9A 3KFYA 3F8ZA 3QL0A 4EJ1A 3QYLA 4ELHA 3RG9A 4X5HA 5JG0X 4HA7A 1BOZA 3NZ6X 5HT4A 4ELEA 4IXFX 1RG7A 3FQVA 3S9UA 3FRDX 3UM5A 1DAJA 2ANQA 3KJSA 3GHVA 3EEKA 1DDSA 3INVA 3F0QX 1RX2A 3CLBA 1DISA 3S7AA 3QG2A 3OAFA 1DF7A 5ECCA 1DIUA 3K74A 1U71A 1ZDRA 1DHIA 1JOMA 3I3RA 3DL5A 4M2XA 2W3MA 5HVBA 1RX7A 3FL8A 1RF7A 3SR5X 3DG8A 3IX9A 3KJRA 4FGHA 3IRNA 1DDRA 3JWFA 4QJZD 6DFRA 5HT5A 5HVEA 4XT7A 1RA9A 4QI9A 3ROAA 4DDRA 3M09A 4CD2A 4XT8A 4M7UA 3ZPGA 3NTZA 2QK8A 1BZFA 3F0UX 5HPBA 1DHJA 5HF2X 1MVTA 2OBCA 3RO9A 3FQOA 1CZ3A 3F0XX 3NZBX 1J3IA 2INQA 4KBNA 3NZDA 1DG7A 4XT5A 4XT6A 1RB2A 3JTWA 1S3WA 3SRQX 1DYIA 4PDJA 1M78A 3GI2A 2KGKA 2C2TA 4GH8A 1PD8A 2W3BA 4G95A 5DXVA 4XE6X 1DRHA 3TQAA 3IROA 3QLSA 2BL9A 3CSEA 1RX1A 1U70A 3F91A 4ELGA 2GD9A 3VCOA 2W9TA 3JW3A 3FQFA 4I1NA 3IRMA 3NZCX 2G6VA 1RX3A 2BLBA 3FYVX 4XECX 2B3ZA 4RGCA 3EIGA 1RH3A 3SA1A 3M08A 4Q0DA 1RE7A 1VDRA 1DLRA 4KJJA 4KJKA 1RX6A 3LG4A 5CCCA 1S3YA 4Q0EA 3NXOA 4KYAA 4HOEA 4KY8A 3DGAA 4I13A 5HF0X 1OHJA 2FZIA 3DFRA 4OSGA 4QJCA 4EILA 1VJ3A 3F0VX 2P4GA 3FQZA 1RA2A 2ANOA 3DAUA 2C2SA 4H95A 3FL9A 3QLWA 3FYWX 1IA4A 1DR4A 3KY8A 4P3RA 5E8QA 1DR5A 4NX7A 3SAIA 4TU5X 4LAGX 1RX9A 1U72A 3FQ0A 5EAJA 3TQ8A 4M6JA 4ELBA 4M6KA 2W9HA 5U26A 4DPDA 1RA8A 4FGGA 1KMVA 3NXRA 4KM0A 1LY3A 4QLGA 4PSSA 3N0HA 5FDAA 1AO8A 3EX8A 3CL9A 3F0SX 3NXXA 1IA2A 4FHBA 2BLAA 4KNEA 4PTJA 3QLZA 4DP3A 3QFXA 3JVXA 3EELA 5HUIA 4XRBA 3GHCA 1DR7A 4G3MA 4KFJA 3K2HA 1M79A 3JWCA 4KD7A 3FRAX 5DFRA 1M7AA 2XW7A 4P68A 1DR1A 2AZNA 4HOGA 4H97A 4PSTA 1DG8A 4DFRA 2W9GA 3Q1HA 1PDBA 4KEBA 1KLKA 4Q67A 3FQCA 3FRBX 5HSRA 4PSYA 4EIZA 3DRCA 1YHOA 2L28A 3DL6A 2W3WA 3NXTA 2HXVA 1J3JA 2O7PA 2D0KA 1LUDA 1AI9A 1E26A 2OIPA 1DHFA 4IXGX 1RA1A 4QLFA 5HSUA 1MVSA 8DFRA 1S3UA 1JOLA 2CD2A 4XT4A 3UM8A 1RX5A 4IXED 4X5JA 3QL3A 3HBBA 3NZ9X 3F8YA 3NZAX 4ELFA 3JWKA 4ECKA 4EIGA 4HA9A 4H96A 4G8ZX 2FZHA 3SQYX 3E0BA 4KAKA 1RB3A 4LAEX 5U27A 5HQYA 4PTHA 1DLSA 2DRCA 2DHFA 4KY4A 3IA5A 4KLXA 1AOEA 2W3VA 2D5NA 4KJLA 3HJ3A 4KM2A 1DR3A 1DG5A 1DRBA 1DYRA 3OCHA 3TQBA 2CIGA 2BLCA 4Q6AA 3SRSX 1SEJA 3JSUA 4X5GA 1HFRA 3UM6A 4QLEA 3I8AX 3FREX 3NXYA 1DREA 4X5FA 1DRFA 2W9SA 3JWMA 3NXVA 1OHKA 3ZPCA 1S3VA 3F0BX 1TDRA 3FY9X 3QLRA 3FS6A 1IA3A 4H98A 2H2QA 4M7VA 7DFRA 4KL9A 1HFQA 3SRRX 4HOFA 5CC9A 3QLXA 1KMSA 3S3VA 3R33A 3FY8X 2HQPA 2W3AA 3GHWA 3JW5A 3K45A 1D1GA 3L3RA 3KGYA 4LEKX 5JA3A 3GYFA 3SH2A 3TD8A
chains in the Genus database with same CATH topology
3IA4A 4NX6A 1RX4A 1PD9A 5HI6A 1RC4A 4P66A 3QLYA 1IA1A 2ZZAA 2HM9A 1RD7A 4QHVA 5HQZA 3QGTA 1QZFA 5ECXA 2ITHA 4LAHX 1DRAA 1RA3A 1HFPA 2FZJA 3FRFX 3NRRA 1RX8A 1DR2A 3D84X 3SGYA 3D80A 1JUVA 3SA2A 3CD2A 1J3KA 3K47A 1CD2A 3DATA 1DYHA 4DPHA 4M6LA 3SRUX 1DYJA 1DR6A 4X5IA 2LF1A 1LY4A 2JYBA 4P3QA 3EEMA 3SRWX 4OR7A 3EEJA 3NU0A 3QYOA 3TQ9A 3KFYA 3F8ZA 3QL0A 4EJ1A 3QYLA 4ELHA 3RG9A 4X5HA 5JG0X 4HA7A 1BOZA 3NZ6X 5HT4A 4ELEA 4IXFX 1RG7A 3FQVA 3S9UA 3FRDX 3UM5A 1DAJA 2ANQA 3KJSA 3GHVA 3EEKA 1DDSA 3INVA 3F0QX 1RX2A 3CLBA 1DISA 3S7AA 3QG2A 3OAFA 1DF7A 5ECCA 1DIUA 3K74A 1U71A 1ZDRA 1DHIA 1JOMA 3I3RA 3DL5A 4M2XA 2W3MA 5HVBA 1RX7A 3FL8A 1RF7A 3SR5X 3DG8A 3IX9A 3KJRA 4FGHA 3IRNA 1DDRA 3JWFA 4QJZD 6DFRA 5HT5A 5HVEA 4XT7A 1RA9A 4QI9A 3ROAA 4DDRA 3M09A 4CD2A 4XT8A 4M7UA 3ZPGA 3NTZA 2QK8A 1BZFA 3F0UX 5HPBA 1DHJA 5HF2X 1MVTA 2OBCA 3RO9A 3FQOA 1CZ3A 3F0XX 3NZBX 1J3IA 2INQA 4KBNA 3NZDA 1DG7A 4XT5A 4XT6A 1RB2A 3JTWA 1S3WA 3SRQX 1DYIA 4PDJA 1M78A 3GI2A 2KGKA 2C2TA 4GH8A 1PD8A 2W3BA 4G95A 5DXVA 4XE6X 1DRHA 3TQAA 3IROA 3QLSA 2BL9A 3CSEA 1RX1A 1U70A 3F91A 4ELGA 2GD9A 3VCOA 2W9TA 3JW3A 3FQFA 4I1NA 3IRMA 3NZCX 2G6VA 1RX3A 2BLBA 3FYVX 4XECX 2B3ZA 4RGCA 3EIGA 1RH3A 3SA1A 3M08A 4Q0DA 1RE7A 1VDRA 1DLRA 4KJJA 4KJKA 1RX6A 3LG4A 5CCCA 1S3YA 4Q0EA 3NXOA 4KYAA 4HOEA 4KY8A 3DGAA 4I13A 5HF0X 1OHJA 2FZIA 3DFRA 4OSGA 4QJCA 4EILA 1VJ3A 3F0VX 2P4GA 3FQZA 1RA2A 2ANOA 3DAUA 2C2SA 4H95A 3FL9A 3QLWA 3FYWX 1IA4A 1DR4A 3KY8A 4P3RA 5E8QA 1DR5A 4NX7A 3SAIA 4TU5X 4LAGX 1RX9A 1U72A 3FQ0A 5EAJA 3TQ8A 4M6JA 4ELBA 4M6KA 2W9HA 5U26A 4DPDA 1RA8A 4FGGA 1KMVA 3NXRA 4KM0A 1LY3A 4QLGA 4PSSA 3N0HA 5FDAA 1AO8A 3EX8A 3CL9A 3F0SX 3NXXA 1IA2A 4FHBA 2BLAA 4KNEA 4PTJA 3QLZA 4DP3A 3QFXA 3JVXA 3EELA 5HUIA 4XRBA 3GHCA 1DR7A 4G3MA 4KFJA 3K2HA 1M79A 3JWCA 4KD7A 3FRAX 5DFRA 1M7AA 2XW7A 4P68A 1DR1A 2AZNA 4HOGA 4H97A 4PSTA 1DG8A 4DFRA 2W9GA 3Q1HA 1PDBA 4KEBA 1KLKA 4Q67A 3FQCA 3FRBX 5HSRA 4PSYA 4EIZA 3DRCA 1YHOA 2L28A 3DL6A 2W3WA 3NXTA 2HXVA 1J3JA 2O7PA 2D0KA 1LUDA 1AI9A 1E26A 2OIPA 1DHFA 4IXGX 1RA1A 4QLFA 5HSUA 1MVSA 8DFRA 1S3UA 1JOLA 2CD2A 4XT4A 3UM8A 1RX5A 4IXED 4X5JA 3QL3A 3HBBA 3NZ9X 3F8YA 3NZAX 4ELFA 3JWKA 4ECKA 4EIGA 4HA9A 4H96A 4G8ZX 2FZHA 3SQYX 3E0BA 4KAKA 1RB3A 4LAEX 5U27A 5HQYA 4PTHA 1DLSA 2DRCA 2DHFA 4KY4A 3IA5A 4KLXA 1AOEA 2W3VA 2D5NA 4KJLA 3HJ3A 4KM2A 1DR3A 1DG5A 1DRBA 1DYRA 3OCHA 3TQBA 2CIGA 2BLCA 4Q6AA 3SRSX 1SEJA 3JSUA 4X5GA 1HFRA 3UM6A 4QLEA 3I8AX 3FREX 3NXYA 1DREA 4X5FA 1DRFA 2W9SA 3JWMA 3NXVA 1OHKA 3ZPCA 1S3VA 3F0BX 1TDRA 3FY9X 3QLRA 3FS6A 1IA3A 4H98A 2H2QA 4M7VA 7DFRA 4KL9A 1HFQA 3SRRX 4HOFA 5CC9A 3QLXA 1KMSA 3S3VA 3R33A 3FY8X 2HQPA 2W3AA 3GHWA 3JW5A 3K45A 1D1GA 3L3RA 3KGYA 4LEKX 5JA3A 3GYFA 3SH2A 3TD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IA4 A;  4NX6 A;  1RX4 A;  1PD9 A;  5HI6 A;  1RC4 A;  4P66 A;  3QLY A;  1IA1 A;  2ZZA A;  2HM9 A;  1RD7 A;  4QHV A;  5HQZ A;  3QGT A;  1QZF A;  5ECX A;  2ITH A;  4LAH X;  1DRA A;  1RA3 A;  1HFP A;  2FZJ A;  3FRF X;  3NRR A;  1RX8 A;  1DR2 A;  3D84 X;  3SGY A;  3D80 A;  1JUV A;  3SA2 A;  3CD2 A;  1J3K A;  3K47 A;  1CD2 A;  3DAT A;  1DYH A;  4DPH A;  4M6L A;  3SRU X;  1DYJ A;  1DR6 A;  4X5I A;  2LF1 A;  1LY4 A;  2JYB A;  4P3Q A;  3EEM A;  3SRW X;  4OR7 A;  3EEJ A;  3NU0 A;  3QYO A;  3TQ9 A;  3KFY A;  3F8Z A;  3QL0 A;  4EJ1 A;  3QYL A;  4ELH A;  3RG9 A;  4X5H A;  5JG0 X;  4HA7 A;  1BOZ A;  3NZ6 X;  5HT4 A;  4ELE A;  4IXF X;  1RG7 A;  3FQV A;  3S9U A;  3FRD X;  3UM5 A;  1DAJ A;  2ANQ A;  3KJS A;  3GHV A;  3EEK A;  1DDS A;  3INV A;  3F0Q X;  1RX2 A;  3CLB A;  1DIS A;  3S7A A;  3QG2 A;  3OAF A;  1DF7 A;  5ECC A;  1DIU A;  3K74 A;  1U71 A;  1ZDR A;  1DHI A;  1JOM A;  3I3R A;  3DL5 A;  4M2X A;  2W3M A;  5HVB A;  1RX7 A;  3FL8 A;  1RF7 A;  3SR5 X;  3DG8 A;  3IX9 A;  3KJR A;  4FGH A;  3IRN A;  1DDR A;  3JWF A;  4QJZ D;  6DFR A;  5HT5 A;  5HVE A;  4XT7 A;  1RA9 A;  4QI9 A;  3ROA A;  4DDR A;  3M09 A;  4CD2 A;  4XT8 A;  4M7U A;  3ZPG A;  3NTZ A;  2QK8 A;  1BZF A;  3F0U X;  5HPB A;  1DHJ A;  5HF2 X;  1MVT A;  2OBC A;  3RO9 A;  3FQO A;  1CZ3 A;  3F0X X;  3NZB X;  1J3I A;  2INQ A;  4KBN A;  3NZD A;  1DG7 A;  4XT5 A;  4XT6 A;  1RB2 A;  3JTW A;  1S3W A;  3SRQ X;  1DYI A;  4PDJ A;  1M78 A;  3GI2 A;  2KGK A;  2C2T A;  4GH8 A;  1PD8 A;  2W3B A;  4G95 A;  5DXV A;  4XE6 X;  1DRH A;  3TQA A;  3IRO A;  3QLS A;  2BL9 A;  3CSE A;  1RX1 A;  1U70 A;  3F91 A;  4ELG A;  2GD9 A;  3VCO A;  2W9T A;  3JW3 A;  3FQF A;  4I1N A;  3IRM A;  3NZC X;  2G6V A;  1RX3 A;  2BLB A;  3FYV X;  4XEC X;  2B3Z A;  4RGC A;  3EIG A;  1RH3 A;  3SA1 A;  3M08 A;  4Q0D A;  1RE7 A;  1VDR A;  1DLR A;  4KJJ A;  4KJK A;  1RX6 A;  3LG4 A;  5CCC A;  1S3Y A;  4Q0E A;  3NXO A;  4KYA A;  4HOE A;  4KY8 A;  3DGA A;  4I13 A;  5HF0 X;  1OHJ A;  2FZI A;  3DFR A;  4OSG A;  4QJC A;  4EIL A;  1VJ3 A;  3F0V X;  2P4G A;  3FQZ A;  1RA2 A;  2ANO A;  3DAU A;  2C2S A;  4H95 A;  3FL9 A;  3QLW A;  3FYW X;  1IA4 A;  1DR4 A;  3KY8 A;  4P3R A;  5E8Q A;  1DR5 A;  4NX7 A;  3SAI A;  4TU5 X;  4LAG X;  1RX9 A;  1U72 A;  3FQ0 A;  5EAJ A;  3TQ8 A;  4M6J A;  4ELB A;  4M6K A;  2W9H A;  5U26 A;  4DPD A;  1RA8 A;  4FGG A;  1KMV A;  3NXR A;  4KM0 A;  1LY3 A;  4QLG A;  4PSS A;  3N0H A;  5FDA A;  1AO8 A;  3EX8 A;  3CL9 A;  3F0S X;  3NXX A;  1IA2 A;  4FHB A;  2BLA A;  4KNE A;  4PTJ A;  3QLZ A;  4DP3 A;  3QFX A;  3JVX A;  3EEL A;  5HUI A;  4XRB A;  3GHC A;  1DR7 A;  4G3M A;  4KFJ A;  3K2H A;  1M79 A;  3JWC A;  4KD7 A;  3FRA X;  5DFR A;  1M7A A;  2XW7 A;  4P68 A;  1DR1 A;  2AZN A;  4HOG A;  4H97 A;  4PST A;  1DG8 A;  4DFR A;  2W9G A;  3Q1H A;  1PDB A;  4KEB A;  1KLK A;  4Q67 A;  3FQC A;  3FRB X;  5HSR A;  4PSY A;  4EIZ A;  3DRC A;  1YHO A;  2L28 A;  3DL6 A;  2W3W A;  3NXT A;  2HXV A;  1J3J A;  2O7P A;  2D0K A;  1LUD A;  1AI9 A;  1E26 A;  2OIP A;  1DHF A;  4IXG X;  1RA1 A;  4QLF A;  5HSU A;  1MVS A;  8DFR A;  1S3U A;  1JOL A;  2CD2 A;  4XT4 A;  3UM8 A;  1RX5 A;  4IXE D;  4X5J A;  3QL3 A;  3HBB A;  3NZ9 X;  3F8Y A;  3NZA X;  4ELF A;  3JWK A;  4ECK A;  4EIG A;  4HA9 A;  4H96 A;  4G8Z X;  2FZH A;  3SQY X;  3E0B A;  4KAK A;  1RB3 A;  4LAE X;  5U27 A;  5HQY A;  4PTH A;  1DLS A;  2DRC A;  2DHF A;  4KY4 A;  3IA5 A;  4KLX A;  1AOE A;  2W3V A;  2D5N A;  4KJL A;  3HJ3 A;  4KM2 A;  1DR3 A;  1DG5 A;  1DRB A;  1DYR A;  3OCH A;  3TQB A;  2CIG A;  2BLC A;  4Q6A A;  3SRS X;  1SEJ A;  3JSU A;  4X5G A;  1HFR A;  3UM6 A;  4QLE A;  3I8A X;  3FRE X;  3NXY A;  1DRE A;  4X5F A;  1DRF A;  2W9S A;  3JWM A;  3NXV A;  1OHK A;  3ZPC A;  1S3V A;  3F0B X;  1TDR A;  3FY9 X;  3QLR A;  3FS6 A;  1IA3 A;  4H98 A;  2H2Q A;  4M7V A;  7DFR A;  4KL9 A;  1HFQ A;  3SRR X;  4HOF A;  5CC9 A;  3QLX A;  1KMS A;  3S3V A;  3R33 A;  3FY8 X;  2HQP A;  2W3A A;  3GHW A;  3JW5 A;  3K45 A;  1D1G A;  3L3R A;  3KGY A;  4LEK X;  5JA3 A;  3GYF A;  3SH2 A;  3TD8 A; 
#chains in the Genus database with same CATH topology
 3IA4 A;  4NX6 A;  1RX4 A;  1PD9 A;  5HI6 A;  1RC4 A;  4P66 A;  3QLY A;  1IA1 A;  2ZZA A;  2HM9 A;  1RD7 A;  4QHV A;  5HQZ A;  3QGT A;  1QZF A;  5ECX A;  2ITH A;  4LAH X;  1DRA A;  1RA3 A;  1HFP A;  2FZJ A;  3FRF X;  3NRR A;  1RX8 A;  1DR2 A;  3D84 X;  3SGY A;  3D80 A;  1JUV A;  3SA2 A;  3CD2 A;  1J3K A;  3K47 A;  1CD2 A;  3DAT A;  1DYH A;  4DPH A;  4M6L A;  3SRU X;  1DYJ A;  1DR6 A;  4X5I A;  2LF1 A;  1LY4 A;  2JYB A;  4P3Q A;  3EEM A;  3SRW X;  4OR7 A;  3EEJ A;  3NU0 A;  3QYO A;  3TQ9 A;  3KFY A;  3F8Z A;  3QL0 A;  4EJ1 A;  3QYL A;  4ELH A;  3RG9 A;  4X5H A;  5JG0 X;  4HA7 A;  1BOZ A;  3NZ6 X;  5HT4 A;  4ELE A;  4IXF X;  1RG7 A;  3FQV A;  3S9U A;  3FRD X;  3UM5 A;  1DAJ A;  2ANQ A;  3KJS A;  3GHV A;  3EEK A;  1DDS A;  3INV A;  3F0Q X;  1RX2 A;  3CLB A;  1DIS A;  3S7A A;  3QG2 A;  3OAF A;  1DF7 A;  5ECC A;  1DIU A;  3K74 A;  1U71 A;  1ZDR A;  1DHI A;  1JOM A;  3I3R A;  3DL5 A;  4M2X A;  2W3M A;  5HVB A;  1RX7 A;  3FL8 A;  1RF7 A;  3SR5 X;  3DG8 A;  3IX9 A;  3KJR A;  4FGH A;  3IRN A;  1DDR A;  3JWF A;  4QJZ D;  6DFR A;  5HT5 A;  5HVE A;  4XT7 A;  1RA9 A;  4QI9 A;  3ROA A;  4DDR A;  3M09 A;  4CD2 A;  4XT8 A;  4M7U A;  3ZPG A;  3NTZ A;  2QK8 A;  1BZF A;  3F0U X;  5HPB A;  1DHJ A;  5HF2 X;  1MVT A;  2OBC A;  3RO9 A;  3FQO A;  1CZ3 A;  3F0X X;  3NZB X;  1J3I A;  2INQ A;  4KBN A;  3NZD A;  1DG7 A;  4XT5 A;  4XT6 A;  1RB2 A;  3JTW A;  1S3W A;  3SRQ X;  1DYI A;  4PDJ A;  1M78 A;  3GI2 A;  2KGK A;  2C2T A;  4GH8 A;  1PD8 A;  2W3B A;  4G95 A;  5DXV A;  4XE6 X;  1DRH A;  3TQA A;  3IRO A;  3QLS A;  2BL9 A;  3CSE A;  1RX1 A;  1U70 A;  3F91 A;  4ELG A;  2GD9 A;  3VCO A;  2W9T A;  3JW3 A;  3FQF A;  4I1N A;  3IRM A;  3NZC X;  2G6V A;  1RX3 A;  2BLB A;  3FYV X;  4XEC X;  2B3Z A;  4RGC A;  3EIG A;  1RH3 A;  3SA1 A;  3M08 A;  4Q0D A;  1RE7 A;  1VDR A;  1DLR A;  4KJJ A;  4KJK A;  1RX6 A;  3LG4 A;  5CCC A;  1S3Y A;  4Q0E A;  3NXO A;  4KYA A;  4HOE A;  4KY8 A;  3DGA A;  4I13 A;  5HF0 X;  1OHJ A;  2FZI A;  3DFR A;  4OSG A;  4QJC A;  4EIL A;  1VJ3 A;  3F0V X;  2P4G A;  3FQZ A;  1RA2 A;  2ANO A;  3DAU A;  2C2S A;  4H95 A;  3FL9 A;  3QLW A;  3FYW X;  1IA4 A;  1DR4 A;  3KY8 A;  4P3R A;  5E8Q A;  1DR5 A;  4NX7 A;  3SAI A;  4TU5 X;  4LAG X;  1RX9 A;  1U72 A;  3FQ0 A;  5EAJ A;  3TQ8 A;  4M6J A;  4ELB A;  4M6K A;  2W9H A;  5U26 A;  4DPD A;  1RA8 A;  4FGG A;  1KMV A;  3NXR A;  4KM0 A;  1LY3 A;  4QLG A;  4PSS A;  3N0H A;  5FDA A;  1AO8 A;  3EX8 A;  3CL9 A;  3F0S X;  3NXX A;  1IA2 A;  4FHB A;  2BLA A;  4KNE A;  4PTJ A;  3QLZ A;  4DP3 A;  3QFX A;  3JVX A;  3EEL A;  5HUI A;  4XRB A;  3GHC A;  1DR7 A;  4G3M A;  4KFJ A;  3K2H A;  1M79 A;  3JWC A;  4KD7 A;  3FRA X;  5DFR A;  1M7A A;  2XW7 A;  4P68 A;  1DR1 A;  2AZN A;  4HOG A;  4H97 A;  4PST A;  1DG8 A;  4DFR A;  2W9G A;  3Q1H A;  1PDB A;  4KEB A;  1KLK A;  4Q67 A;  3FQC A;  3FRB X;  5HSR A;  4PSY A;  4EIZ A;  3DRC A;  1YHO A;  2L28 A;  3DL6 A;  2W3W A;  3NXT A;  2HXV A;  1J3J A;  2O7P A;  2D0K A;  1LUD A;  1AI9 A;  1E26 A;  2OIP A;  1DHF A;  4IXG X;  1RA1 A;  4QLF A;  5HSU A;  1MVS A;  8DFR A;  1S3U A;  1JOL A;  2CD2 A;  4XT4 A;  3UM8 A;  1RX5 A;  4IXE D;  4X5J A;  3QL3 A;  3HBB A;  3NZ9 X;  3F8Y A;  3NZA X;  4ELF A;  3JWK A;  4ECK A;  4EIG A;  4HA9 A;  4H96 A;  4G8Z X;  2FZH A;  3SQY X;  3E0B A;  4KAK A;  1RB3 A;  4LAE X;  5U27 A;  5HQY A;  4PTH A;  1DLS A;  2DRC A;  2DHF A;  4KY4 A;  3IA5 A;  4KLX A;  1AOE A;  2W3V A;  2D5N A;  4KJL A;  3HJ3 A;  4KM2 A;  1DR3 A;  1DG5 A;  1DRB A;  1DYR A;  3OCH A;  3TQB A;  2CIG A;  2BLC A;  4Q6A A;  3SRS X;  1SEJ A;  3JSU A;  4X5G A;  1HFR A;  3UM6 A;  4QLE A;  3I8A X;  3FRE X;  3NXY A;  1DRE A;  4X5F A;  1DRF A;  2W9S A;  3JWM A;  3NXV A;  1OHK A;  3ZPC A;  1S3V A;  3F0B X;  1TDR A;  3FY9 X;  3QLR A;  3FS6 A;  1IA3 A;  4H98 A;  2H2Q A;  4M7V A;  7DFR A;  4KL9 A;  1HFQ A;  3SRR X;  4HOF A;  5CC9 A;  3QLX A;  1KMS A;  3S3V A;  3R33 A;  3FY8 X;  2HQP A;  2W3A A;  3GHW A;  3JW5 A;  3K45 A;  1D1G A;  3L3R A;  3KGY A;  4LEK X;  5JA3 A;  3GYF A;  3SH2 A;  3TD8 A; 
#chains in the Genus database with same CATH homology
 3IA4 A;  4NX6 A;  1RX4 A;  1PD9 A;  5HI6 A;  1RC4 A;  4P66 A;  3QLY A;  1IA1 A;  2ZZA A;  2HM9 A;  1RD7 A;  4QHV A;  5HQZ A;  3QGT A;  1QZF A;  5ECX A;  2ITH A;  4LAH X;  1DRA A;  1RA3 A;  1HFP A;  2FZJ A;  3FRF X;  3NRR A;  1RX8 A;  1DR2 A;  3D84 X;  3SGY A;  3D80 A;  1JUV A;  3SA2 A;  3CD2 A;  1J3K A;  3K47 A;  1CD2 A;  3DAT A;  1DYH A;  4DPH A;  4M6L A;  3SRU X;  1DYJ A;  1DR6 A;  4X5I A;  2LF1 A;  1LY4 A;  2JYB A;  4P3Q A;  3EEM A;  3SRW X;  4OR7 A;  3EEJ A;  3NU0 A;  3QYO A;  3TQ9 A;  3KFY A;  3F8Z A;  3QL0 A;  4EJ1 A;  3QYL A;  4ELH A;  3RG9 A;  4X5H A;  5JG0 X;  4HA7 A;  1BOZ A;  3NZ6 X;  5HT4 A;  4ELE A;  4IXF X;  1RG7 A;  3FQV A;  3S9U A;  3FRD X;  3UM5 A;  1DAJ A;  2ANQ A;  3KJS A;  3GHV A;  3EEK A;  1DDS A;  3INV A;  3F0Q X;  1RX2 A;  3CLB A;  1DIS A;  3S7A A;  3QG2 A;  3OAF A;  1DF7 A;  5ECC A;  1DIU A;  3K74 A;  1U71 A;  1ZDR A;  1DHI A;  1JOM A;  3I3R A;  3DL5 A;  4M2X A;  2W3M A;  5HVB A;  1RX7 A;  3FL8 A;  1RF7 A;  3SR5 X;  3DG8 A;  3IX9 A;  3KJR A;  4FGH A;  3IRN A;  1DDR A;  3JWF A;  4QJZ D;  6DFR A;  5HT5 A;  5HVE A;  4XT7 A;  1RA9 A;  4QI9 A;  3ROA A;  4DDR A;  3M09 A;  4CD2 A;  4XT8 A;  4M7U A;  3ZPG A;  3NTZ A;  2QK8 A;  1BZF A;  3F0U X;  5HPB A;  1DHJ A;  5HF2 X;  1MVT A;  2OBC A;  3RO9 A;  3FQO A;  1CZ3 A;  3F0X X;  3NZB X;  1J3I A;  2INQ A;  4KBN A;  3NZD A;  1DG7 A;  4XT5 A;  4XT6 A;  1RB2 A;  3JTW A;  1S3W A;  3SRQ X;  1DYI A;  4PDJ A;  1M78 A;  3GI2 A;  2KGK A;  2C2T A;  4GH8 A;  1PD8 A;  2W3B A;  4G95 A;  5DXV A;  4XE6 X;  1DRH A;  3TQA A;  3IRO A;  3QLS A;  2BL9 A;  3CSE A;  1RX1 A;  1U70 A;  3F91 A;  4ELG A;  2GD9 A;  3VCO A;  2W9T A;  3JW3 A;  3FQF A;  4I1N A;  3IRM A;  3NZC X;  2G6V A;  1RX3 A;  2BLB A;  3FYV X;  4XEC X;  2B3Z A;  4RGC A;  3EIG A;  1RH3 A;  3SA1 A;  3M08 A;  4Q0D A;  1RE7 A;  1VDR A;  1DLR A;  4KJJ A;  4KJK A;  1RX6 A;  3LG4 A;  5CCC A;  1S3Y A;  4Q0E A;  3NXO A;  4KYA A;  4HOE A;  4KY8 A;  3DGA A;  4I13 A;  5HF0 X;  1OHJ A;  2FZI A;  3DFR A;  4OSG A;  4QJC A;  4EIL A;  1VJ3 A;  3F0V X;  2P4G A;  3FQZ A;  1RA2 A;  2ANO A;  3DAU A;  2C2S A;  4H95 A;  3FL9 A;  3QLW A;  3FYW X;  1IA4 A;  1DR4 A;  3KY8 A;  4P3R A;  5E8Q A;  1DR5 A;  4NX7 A;  3SAI A;  4TU5 X;  4LAG X;  1RX9 A;  1U72 A;  3FQ0 A;  5EAJ A;  3TQ8 A;  4M6J A;  4ELB A;  4M6K A;  2W9H A;  5U26 A;  4DPD A;  1RA8 A;  4FGG A;  1KMV A;  3NXR A;  4KM0 A;  1LY3 A;  4QLG A;  4PSS A;  3N0H A;  5FDA A;  1AO8 A;  3EX8 A;  3CL9 A;  3F0S X;  3NXX A;  1IA2 A;  4FHB A;  2BLA A;  4KNE A;  4PTJ A;  3QLZ A;  4DP3 A;  3QFX A;  3JVX A;  3EEL A;  5HUI A;  4XRB A;  3GHC A;  1DR7 A;  4G3M A;  4KFJ A;  3K2H A;  1M79 A;  3JWC A;  4KD7 A;  3FRA X;  5DFR A;  1M7A A;  2XW7 A;  4P68 A;  1DR1 A;  2AZN A;  4HOG A;  4H97 A;  4PST A;  1DG8 A;  4DFR A;  2W9G A;  3Q1H A;  1PDB A;  4KEB A;  1KLK A;  4Q67 A;  3FQC A;  3FRB X;  5HSR A;  4PSY A;  4EIZ A;  3DRC A;  1YHO A;  2L28 A;  3DL6 A;  2W3W A;  3NXT A;  2HXV A;  1J3J A;  2O7P A;  2D0K A;  1LUD A;  1AI9 A;  1E26 A;  2OIP A;  1DHF A;  4IXG X;  1RA1 A;  4QLF A;  5HSU A;  1MVS A;  8DFR A;  1S3U A;  1JOL A;  2CD2 A;  4XT4 A;  3UM8 A;  1RX5 A;  4IXE D;  4X5J A;  3QL3 A;  3HBB A;  3NZ9 X;  3F8Y A;  3NZA X;  4ELF A;  3JWK A;  4ECK A;  4EIG A;  4HA9 A;  4H96 A;  4G8Z X;  2FZH A;  3SQY X;  3E0B A;  4KAK A;  1RB3 A;  4LAE X;  5U27 A;  5HQY A;  4PTH A;  1DLS A;  2DRC A;  2DHF A;  4KY4 A;  3IA5 A;  4KLX A;  1AOE A;  2W3V A;  2D5N A;  4KJL A;  3HJ3 A;  4KM2 A;  1DR3 A;  1DG5 A;  1DRB A;  1DYR A;  3OCH A;  3TQB A;  2CIG A;  2BLC A;  4Q6A A;  3SRS X;  1SEJ A;  3JSU A;  4X5G A;  1HFR A;  3UM6 A;  4QLE A;  3I8A X;  3FRE X;  3NXY A;  1DRE A;  4X5F A;  1DRF A;  2W9S A;  3JWM A;  3NXV A;  1OHK A;  3ZPC A;  1S3V A;  3F0B X;  1TDR A;  3FY9 X;  3QLR A;  3FS6 A;  1IA3 A;  4H98 A;  2H2Q A;  4M7V A;  7DFR A;  4KL9 A;  1HFQ A;  3SRR X;  4HOF A;  5CC9 A;  3QLX A;  1KMS A;  3S3V A;  3R33 A;  3FY8 X;  2HQP A;  2W3A A;  3GHW A;  3JW5 A;  3K45 A;  1D1G A;  3L3R A;  3KGY A;  4LEK X;  5JA3 A;  3GYF A;  3SH2 A;  3TD8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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