4TZIA

Structure of unliganded lyn sh2 domain
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
110
structure length
110
Chain Sequence
AKVNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVIKHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords Tyrosine-protein kinase Lyn
total genus 26
structure length 110
sequence length 110
chains with identical sequence B
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2014-07-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4tziA00
3VRYA 1FU6A 5DC9A 1YVLA 3BKBA 2H46E 2EYZA 3CD3A 3CWGA 2DX0A 1O4JA 4ROJA 3PQZA 1B47A 1O4IA 4E93A 3WA4A 5IBSA 1A1EA 2H8HA 1O45A 4LUDA 2LCTA 1BLKA 2DVJA 3VRQA 1LKLA 3IN8A 4FL2A 3CBLA 1FU5A 4M4ZA 4XZ1A 1X0NA 3EACA 2IUHA 5IBMA 1Y1UA 3IN7A 3VRZA 1O48A 5HKZA 2L6KA 2GE9A 1AYAA 2CS0A 2ETZA 3HCKA 2MK2A 4XZ0A 4A4CA 1LUKA 3PFVA 4K44A 3HIZB 2EOBA 3VS1A 5HKWA 1JYUA 3MAZA 2K79B 1TCEA 1BG1A 3VGOA 1F1WA 2OZOA 2PTKA 3N8MA 2HDVA 2SHPA 1SHDA 4OHHA 2MC1A 1FHSA 3EAZA 4U1PA 1BKLA 4QSYA 3VS4A 3BUMB 1M27A 3PJPA 1P13A 1O43A 3IMJA 1D1ZA 2FCIA 4F59A 3CXLA 2EO6A 1AYBA 1PICA 3MXCA 1TZEE 1SHAA 2PLDA 1CWEA 3VS2A 4A4BA 2RSYA 1O4HA 4L1BB 2H5KA 1O44A 1AOTF 2KK6A 1KC2A 1A07A 2EYYA 2AOAA 1O47A 2L3TA 1A08A 5AULA 3OV1A 5KAZA 1YVHA 1FBVA 2XP1A 5BO4A 1M61A 3UYOA 3QWXX 1HCTB 1NZVA 3VRRA 1RQQC 1O4QA 1JYQA 4GWFA 3MXYA 2HUWA 4K2RA 2DCRA 1CSYA 1LCKA 3HHMB 1O4PA 1R1QA 2EO3A 4NWFA 4OHIA 4EY0A 2HMHA 3S9KA 2DLYA 1G83A 4X6SA 3BUNB 5GJIA 2KNOA 1O4DA 2Y1NA 3PSKA 1GHUA 1O46A 5J3XA 3BUOB 1CWDL 3QWYA 1QADA 1R1PA 4OHEA 2K7AB 1BFJA 3TL0A 3US4A 1F2FA 1AOUF 2CIAA 2HDXA 1CJ1A 2QMSA 1JWOA 1Y57A 4LUEA 1SPRA 2RORA 2EYVA 2EKXA 1O4EA 1SHBA 3IMDA 1O4LA 1BLJA 4K11A 1FYRA 4TZIA 2ECDA 1KA7A 1QG1E 4NWGA 5AXIA 4JGHA 2IUGA 1BHFA 3VROA 3PS5A 3UF4A 5CDWA 1BMBA 5DC0B 3GQIB 1AYCA 1BM2A 2ABLA 2LQWA 3BUWB 1O4CA 4H1OA 2BBUA 1BKMA 4U17A 3S8OA 2MRKA 1BF5A 5EEQA 1O4NA 2Y1MA 1JYRA 1LCJA 5HKYA 1O4GA 1SPSA 2YU7A 4JEGA 2DLZA 2C0IA 2FO0A 3GXWA 1XA6A 1UURA 2CR4A 1I3ZA 5I6VA 2PNBA 4JE4A 3VS6A 1A09A 1SKJA 5D0JA 3OB2B 1HCSB 3S8LA 2C0TA 2EU0A 2YSXA 1O4FA 1A81A 1K9AA 2LNXA 3NHNA 1O4RA 1RPYA 1A1BA 4DGPA 1O42A 1OPLA 4OHDA 2CI9A 4GPLB 2CI8A 2L4KA 4F5AA 1IS0A 2JYQA 3S8NA 1O4AA 2PNAA 2C0OA 2CRHA 5EELA 2C9WA 3M7FA 1LKKA 4D8KA 1Z3KA 4P9ZA 2Y3AB 2OQ1A 3GXXA 1A1AA 3OP0A 1BHHA 2GSBA 5EG3B 2IZVA 1FMKA 1X27A 1UUSA 2IUIA 1O4OA 1O4KA 1MILA 1FBZA 1MW4A 2DM0A 1LUIA 5EHRA 1AYDA 2EL8A 1QCFA 4E68A 5DF6A 4H34A 1BFIA 1A1CA 2RVFA 1GRIA 1NZLA 1LUMA 1RJAA 2LQNA 4P9VA 3T04A 4K45A 3N84A 3OVEA 3N7YA 3VS7A 3KFJA 3VRPA 3PLFB 2PLEA 1OO4A 1IJRA 3TKZA 4DGXA 1O4MA 1D4WA 3VS0A 3ZNIA 5DC4A 2CBLA 3C7IA 3K2MA 1JU5A 1OPKA 3VS3A 2SRCA 1KA6A 3PSJA 2AUGA 1AD5A 1ZFPE 3BUXB 3OB1B 3VS5A 2AOBA 4OHLA 1CSZA 5GJHA 4F5BA 1KSWA 1R1SA 1NRVA 2LNWA 4FBNA 1WQUA 1AB2A 4FL3A 2MRJA 4WWQA 1O49A 1H9OA 2B3OA 1O4BA 4EIHA 3VRNA 1BHHB 5EHPA 1D4TA 1X6CA 2MQIA 1O41A 4GL9E 1LUNA 2HCKA 2VIFA 2RMXA 1OO3A
chains in the Genus database with same CATH superfamily
3VRYA 1FU6A 5DC9A 2LRAA 1YVLA 3BKBA 2H46E 2EYZA 3CD3A 3CWGA 2DX0A 1O4JA 4ROJA 3PQZA 1B47A 1O4IA 4E93A 3WA4A 5IBSA 1A1EA 2H8HA 1O45A 4LUDA 2LCTA 1BLKA 2DVJA 3VRQA 1LKLA 3IN8A 4FL2A 3CBLA 1FU5A 4M4ZA 4XZ1A 1X0NA 3EACA 2IUHA 5IBMA 1Y1UA 3IN7A 3VRZA 1O48A 5HKZA 2L6KA 2GE9A 1AYAA 2CS0A 2ETZA 3HCKA 2MK2A 4XZ0A 4A4CA 1LUKA 3PFVA 4K44A 3HIZB 2EOBA 3VS1A 5HKWA 1JYUA 3MAZA 2K79B 1TCEA 1BG1A 3VGOA 1F1WA 2KGYA 2OZOA 2PTKA 3N8MA 2HDVA 2SHPA 1SHDA 4OHHA 2MC1A 1FHSA 3EAZA 4U1PA 1BKLA 4QSYA 3VS4A 3BUMB 1M27A 3PJPA 1P13A 1O43A 3IMJA 1D1ZA 2FCIA 4F59A 3CXLA 2EO6A 1AYBA 1PICA 3MXCA 1TZEE 1SHAA 2PLDA 1CWEA 3VS2A 4A4BA 2RSYA 1O4HA 4L1BB 2H5KA 1O44A 1AOTF 2KK6A 1KC2A 1A07A 2EYYA 2AOAA 1O47A 2L3TA 1A08A 5AULA 3OV1A 5KAZA 1YVHA 1FBVA 2XP1A 5BO4A 1M61A 3UYOA 3QWXX 1HCTB 1NZVA 3VRRA 1RQQC 1O4QA 1JYQA 4GWFA 3MXYA 2HUWA 4K2RA 2DCRA 1CSYA 1LCKA 3HHMB 1O4PA 1R1QA 2EO3A 4NWFA 4OHIA 4EY0A 2HMHA 3S9KA 2DLYA 1G83A 4X6SA 3BUNB 5GJIA 2KNOA 1O4DA 2Y1NA 3PSKA 1GHUA 1O46A 5J3XA 3BUOB 1CWDL 3QWYA 1QADA 1R1PA 4OHEA 2K7AB 1BFJA 3TL0A 3US4A 1F2FA 1AOUF 2CIAA 2HDXA 1CJ1A 2QMSA 1JWOA 1Y57A 4LUEA 1SPRA 2RORA 2EYVA 2EKXA 1O4EA 1SHBA 3IMDA 1O4LA 1BLJA 4K11A 1FYRA 4TZIA 2ECDA 1KA7A 1QG1E 4NWGA 5AXIA 4JGHA 2IUGA 1BHFA 3VROA 3PS5A 3UF4A 5CDWA 1BMBA 5DC0B 3GQIB 1AYCA 1BM2A 2ABLA 2LQWA 3BUWB 1O4CA 4H1OA 2BBUA 1BKMA 4U17A 3S8OA 2MRKA 1BF5A 5EEQA 1O4NA 2Y1MA 1JYRA 1LCJA 5HKYA 1O4GA 1SPSA 2YU7A 4JEGA 2DLZA 2C0IA 2FO0A 3GXWA 1XA6A 1UURA 2CR4A 1I3ZA 5I6VA 2PNBA 4JE4A 3VS6A 1A09A 1SKJA 5D0JA 3OB2B 1HCSB 3K2TA 3S8LA 2C0TA 2EU0A 2YSXA 1O4FA 1A81A 1K9AA 2LNXA 3NHNA 1O4RA 1RPYA 1A1BA 4DGPA 1O42A 1OPLA 4OHDA 2CI9A 4GPLB 2CI8A 2L4KA 4F5AA 1IS0A 2JYQA 3S8NA 1O4AA 2PNAA 2C0OA 2CRHA 5EELA 2C9WA 3M7FA 1LKKA 4D8KA 1Z3KA 4P9ZA 2Y3AB 2OQ1A 3GXXA 1A1AA 3OP0A 1BHHA 2GSBA 5EG3B 2IZVA 1FMKA 1X27A 1UUSA 2IUIA 1O4OA 1O4KA 1MILA 1FBZA 1MW4A 2DM0A 1LUIA 5EHRA 1AYDA 2EL8A 1QCFA 4E68A 5DF6A 4H34A 1BFIA 1A1CA 2RVFA 1GRIA 1NZLA 1LUMA 1RJAA 2LQNA 4P9VA 3T04A 4K45A 3N84A 3LYVA 3OVEA 3N7YA 3VS7A 3KFJA 3VRPA 3PLFB 2PLEA 1OO4A 1IJRA 3TKZA 4DGXA 1O4MA 1D4WA 3VS0A 3ZNIA 5DC4A 2CBLA 3C7IA 3K2MA 1JU5A 1OPKA 3VS3A 2SRCA 1KA6A 3PSJA 2AUGA 1AD5A 1ZFPE 3BUXB 3OB1B 3VS5A 2AOBA 4OHLA 1CSZA 5GJHA 4F5BA 1KSWA 1R1SA 1NRVA 2LNWA 4FBNA 1WQUA 1AB2A 4FL3A 2MRJA 4WWQA 1O49A 1H9OA 2B3OA 1O4BA 4EIHA 3VRNA 1BHHB 5EHPA 1D4TA 1X6CA 2MQIA 1O41A 4GL9E 1LUNA 2HCKA 2VIFA 2RMXA 1OO3A
chains in the Genus database with same CATH topology
3VRYA 1FU6A 5DC9A 1YVLA 3BKBA 2H46E 2EYZA 3CD3A 3CWGA 2DX0A 1O4JA 4ROJA 3PQZA 1B47A 1O4IA 4E93A 3WA4A 5IBSA 1A1EA 2H8HA 1O45A 4LUDA 2LCTA 1BLKA 2DVJA 3VRQA 1LKLA 3IN8A 4FL2A 3CBLA 1FU5A 4M4ZA 4XZ1A 1X0NA 3EACA 2IUHA 5IBMA 1Y1UA 3IN7A 3VRZA 1O48A 5HKZA 2L6KA 2GE9A 1AYAA 2CS0A 2ETZA 3HCKA 2MK2A 4XZ0A 4A4CA 1LUKA 3PFVA 4K44A 3HIZB 2EOBA 3VS1A 5HKWA 1JYUA 3MAZA 2K79B 1TCEA 1BG1A 3VGOA 1F1WA 2OZOA 2PTKA 3N8MA 2HDVA 2SHPA 1SHDA 4OHHA 2MC1A 1FHSA 3EAZA 4U1PA 1BKLA 4QSYA 3VS4A 3BUMB 1M27A 3PJPA 1P13A 1O43A 3IMJA 1D1ZA 2FCIA 4F59A 3CXLA 2EO6A 1AYBA 1PICA 3MXCA 1TZEE 1SHAA 2PLDA 1CWEA 3VS2A 4A4BA 2RSYA 1O4HA 4L1BB 2H5KA 1O44A 1AOTF 2KK6A 1KC2A 1A07A 2EYYA 2AOAA 1O47A 2L3TA 1A08A 5AULA 3OV1A 5KAZA 1YVHA 1FBVA 2XP1A 5BO4A 1M61A 3UYOA 3QWXX 1HCTB 1NZVA 3VRRA 1RQQC 1O4QA 1JYQA 4GWFA 3MXYA 2HUWA 4K2RA 2DCRA 1CSYA 1LCKA 3HHMB 1O4PA 1R1QA 2EO3A 4NWFA 4OHIA 4EY0A 2HMHA 3S9KA 2DLYA 1G83A 4X6SA 3BUNB 5GJIA 2KNOA 1O4DA 2Y1NA 3PSKA 1GHUA 1O46A 5J3XA 3BUOB 1CWDL 3QWYA 1QADA 1R1PA 4OHEA 2K7AB 1BFJA 3TL0A 3US4A 1F2FA 1AOUF 2CIAA 2HDXA 1CJ1A 2QMSA 1JWOA 1Y57A 4LUEA 1SPRA 2RORA 2EYVA 2EKXA 1O4EA 1SHBA 3IMDA 1O4LA 1BLJA 4K11A 1FYRA 4TZIA 2ECDA 1KA7A 1QG1E 4NWGA 5AXIA 4JGHA 2IUGA 1BHFA 3VROA 3PS5A 3UF4A 5CDWA 1BMBA 5DC0B 3GQIB 1AYCA 1BM2A 2ABLA 2LQWA 3BUWB 1O4CA 4H1OA 2BBUA 1BKMA 4U17A 3S8OA 2MRKA 1BF5A 5EEQA 1O4NA 2Y1MA 1JYRA 1LCJA 5HKYA 1O4GA 1SPSA 2YU7A 4JEGA 2DLZA 2C0IA 2FO0A 3GXWA 1XA6A 1UURA 2CR4A 1I3ZA 5I6VA 2PNBA 4JE4A 3VS6A 1A09A 1SKJA 5D0JA 3OB2B 1HCSB 3S8LA 2C0TA 2EU0A 2YSXA 1O4FA 1A81A 1K9AA 2LNXA 3NHNA 1O4RA 1RPYA 1A1BA 4DGPA 1O42A 1OPLA 4OHDA 2CI9A 4GPLB 2CI8A 2L4KA 4F5AA 1IS0A 2JYQA 3S8NA 1O4AA 2PNAA 2C0OA 2CRHA 5EELA 2C9WA 3M7FA 1LKKA 4D8KA 1Z3KA 4P9ZA 2Y3AB 2OQ1A 3GXXA 1A1AA 3OP0A 1BHHA 2GSBA 5EG3B 2IZVA 1FMKA 1X27A 1UUSA 2IUIA 1O4OA 1O4KA 1MILA 1FBZA 1MW4A 2DM0A 1LUIA 5EHRA 1AYDA 2EL8A 1QCFA 4E68A 5DF6A 4H34A 1BFIA 1A1CA 2RVFA 1GRIA 1NZLA 1LUMA 1RJAA 2LQNA 4P9VA 3T04A 4K45A 3N84A 3OVEA 3N7YA 3VS7A 3KFJA 3VRPA 3PLFB 2PLEA 1OO4A 1IJRA 3TKZA 4DGXA 1O4MA 1D4WA 3VS0A 3ZNIA 5DC4A 2CBLA 3C7IA 3K2MA 1JU5A 1OPKA 3VS3A 2SRCA 1KA6A 3PSJA 2AUGA 1AD5A 1ZFPE 3BUXB 3OB1B 3VS5A 2AOBA 4OHLA 1CSZA 5GJHA 4F5BA 1KSWA 1R1SA 1NRVA 2LNWA 4FBNA 1WQUA 1AB2A 4FL3A 2MRJA 4WWQA 1O49A 1H9OA 2B3OA 1O4BA 4EIHA 3VRNA 1BHHB 5EHPA 1D4TA 1X6CA 2MQIA 1O41A 4GL9E 1LUNA 2HCKA 2VIFA 2RMXA 1OO3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VRY A;  1FU6 A;  5DC9 A;  1YVL A;  3BKB A;  2H46 E;  2EYZ A;  3CD3 A;  3CWG A;  2DX0 A;  1O4J A;  4ROJ A;  3PQZ A;  1B47 A;  1O4I A;  4E93 A;  3WA4 A;  5IBS A;  1A1E A;  2H8H A;  1O45 A;  4LUD A;  2LCT A;  1BLK A;  2DVJ A;  3VRQ A;  1LKL A;  3IN8 A;  4FL2 A;  3CBL A;  1FU5 A;  4M4Z A;  4XZ1 A;  1X0N A;  3EAC A;  2IUH A;  5IBM A;  1Y1U A;  3IN7 A;  3VRZ A;  1O48 A;  5HKZ A;  2L6K A;  2GE9 A;  1AYA A;  2CS0 A;  2ETZ A;  3HCK A;  2MK2 A;  4XZ0 A;  4A4C A;  1LUK A;  3PFV A;  4K44 A;  3HIZ B;  2EOB A;  3VS1 A;  5HKW A;  1JYU A;  3MAZ A;  2K79 B;  1TCE A;  1BG1 A;  3VGO A;  1F1W A;  2OZO A;  2PTK A;  3N8M A;  2HDV A;  2SHP A;  1SHD A;  4OHH A;  2MC1 A;  1FHS A;  3EAZ A;  4U1P A;  1BKL A;  4QSY A;  3VS4 A;  3BUM B;  1M27 A;  3PJP A;  1P13 A;  1O43 A;  3IMJ A;  1D1Z A;  2FCI A;  4F59 A;  3CXL A;  2EO6 A;  1AYB A;  1PIC A;  3MXC A;  1TZE E;  1SHA A;  2PLD A;  1CWE A;  3VS2 A;  4A4B A;  2RSY A;  1O4H A;  4L1B B;  2H5K A;  1O44 A;  1AOT F;  2KK6 A;  1KC2 A;  1A07 A;  2EYY A;  2AOA A;  1O47 A;  2L3T A;  1A08 A;  5AUL A;  3OV1 A;  5KAZ A;  1YVH A;  1FBV A;  2XP1 A;  5BO4 A;  1M61 A;  3UYO A;  3QWX X;  1HCT B;  1NZV A;  3VRR A;  1RQQ C;  1O4Q A;  1JYQ A;  4GWF A;  3MXY A;  2HUW A;  4K2R A;  2DCR A;  1CSY A;  1LCK A;  3HHM B;  1O4P A;  1R1Q A;  2EO3 A;  4NWF A;  4OHI A;  4EY0 A;  2HMH A;  3S9K A;  2DLY A;  1G83 A;  4X6S A;  3BUN B;  5GJI A;  2KNO A;  1O4D A;  2Y1N A;  3PSK A;  1GHU A;  1O46 A;  5J3X A;  3BUO B;  1CWD L;  3QWY A;  1QAD A;  1R1P A;  4OHE A;  2K7A B;  1BFJ A;  3TL0 A;  3US4 A;  1F2F A;  1AOU F;  2CIA A;  2HDX A;  1CJ1 A;  2QMS A;  1JWO A;  1Y57 A;  4LUE A;  1SPR A;  2ROR A;  2EYV A;  2EKX A;  1O4E A;  1SHB A;  3IMD A;  1O4L A;  1BLJ A;  4K11 A;  1FYR A;  4TZI A;  2ECD A;  1KA7 A;  1QG1 E;  4NWG A;  5AXI A;  4JGH A;  2IUG A;  1BHF A;  3VRO A;  3PS5 A;  3UF4 A;  5CDW A;  1BMB A;  5DC0 B;  3GQI B;  1AYC A;  1BM2 A;  2ABL A;  2LQW A;  3BUW B;  1O4C A;  4H1O A;  2BBU A;  1BKM A;  4U17 A;  3S8O A;  2MRK A;  1BF5 A;  5EEQ A;  1O4N A;  2Y1M A;  1JYR A;  1LCJ A;  5HKY A;  1O4G A;  1SPS A;  2YU7 A;  4JEG A;  2DLZ A;  2C0I A;  2FO0 A;  3GXW A;  1XA6 A;  1UUR A;  2CR4 A;  1I3Z A;  5I6V A;  2PNB A;  4JE4 A;  3VS6 A;  1A09 A;  1SKJ A;  5D0J A;  3OB2 B;  1HCS B;  3S8L A;  2C0T A;  2EU0 A;  2YSX A;  1O4F A;  1A81 A;  1K9A A;  2LNX A;  3NHN A;  1O4R A;  1RPY A;  1A1B A;  4DGP A;  1O42 A;  1OPL A;  4OHD A;  2CI9 A;  4GPL B;  2CI8 A;  2L4K A;  4F5A A;  1IS0 A;  2JYQ A;  3S8N A;  1O4A A;  2PNA A;  2C0O A;  2CRH A;  5EEL A;  2C9W A;  3M7F A;  1LKK A;  4D8K A;  1Z3K A;  4P9Z A;  2Y3A B;  2OQ1 A;  3GXX A;  1A1A A;  3OP0 A;  1BHH A;  2GSB A;  5EG3 B;  2IZV A;  1FMK A;  1X27 A;  1UUS A;  2IUI A;  1O4O A;  1O4K A;  1MIL A;  1FBZ A;  1MW4 A;  2DM0 A;  1LUI A;  5EHR A;  1AYD A;  2EL8 A;  1QCF A;  4E68 A;  5DF6 A;  4H34 A;  1BFI A;  1A1C A;  2RVF A;  1GRI A;  1NZL A;  1LUM A;  1RJA A;  2LQN A;  4P9V A;  3T04 A;  4K45 A;  3N84 A;  3OVE A;  3N7Y A;  3VS7 A;  3KFJ A;  3VRP A;  3PLF B;  2PLE A;  1OO4 A;  1IJR A;  3TKZ A;  4DGX A;  1O4M A;  1D4W A;  3VS0 A;  3ZNI A;  5DC4 A;  2CBL A;  3C7I A;  3K2M A;  1JU5 A;  1OPK A;  3VS3 A;  2SRC A;  1KA6 A;  3PSJ A;  2AUG A;  1AD5 A;  1ZFP E;  3BUX B;  3OB1 B;  3VS5 A;  2AOB A;  4OHL A;  1CSZ A;  5GJH A;  4F5B A;  1KSW A;  1R1S A;  1NRV A;  2LNW A;  4FBN A;  1WQU A;  1AB2 A;  4FL3 A;  2MRJ A;  4WWQ A;  1O49 A;  1H9O A;  2B3O A;  1O4B A;  4EIH A;  3VRN A;  1BHH B;  5EHP A;  1D4T A;  1X6C A;  2MQI A;  1O41 A;  4GL9 E;  1LUN A;  2HCK A;  2VIF A;  2RMX A;  1OO3 A; 
#chains in the Genus database with same CATH topology
 3VRY A;  1FU6 A;  5DC9 A;  2LRA A;  1YVL A;  3BKB A;  2H46 E;  2EYZ A;  3CD3 A;  3CWG A;  2DX0 A;  1O4J A;  4ROJ A;  3PQZ A;  1B47 A;  1O4I A;  4E93 A;  3WA4 A;  5IBS A;  1A1E A;  2H8H A;  1O45 A;  4LUD A;  2LCT A;  1BLK A;  2DVJ A;  3VRQ A;  1LKL A;  3IN8 A;  4FL2 A;  3CBL A;  1FU5 A;  4M4Z A;  4XZ1 A;  1X0N A;  3EAC A;  2IUH A;  5IBM A;  1Y1U A;  3IN7 A;  3VRZ A;  1O48 A;  5HKZ A;  2L6K A;  2GE9 A;  1AYA A;  2CS0 A;  2ETZ A;  3HCK A;  2MK2 A;  4XZ0 A;  4A4C A;  1LUK A;  3PFV A;  4K44 A;  3HIZ B;  2EOB A;  3VS1 A;  5HKW A;  1JYU A;  3MAZ A;  2K79 B;  1TCE A;  1BG1 A;  3VGO A;  1F1W A;  2KGY A;  2OZO A;  2PTK A;  3N8M A;  2HDV A;  2SHP A;  1SHD A;  4OHH A;  2MC1 A;  1FHS A;  3EAZ A;  4U1P A;  1BKL A;  4QSY A;  3VS4 A;  3BUM B;  1M27 A;  3PJP A;  1P13 A;  1O43 A;  3IMJ A;  1D1Z A;  2FCI A;  4F59 A;  3CXL A;  2EO6 A;  1AYB A;  1PIC A;  3MXC A;  1TZE E;  1SHA A;  2PLD A;  1CWE A;  3VS2 A;  4A4B A;  2RSY A;  1O4H A;  4L1B B;  2H5K A;  1O44 A;  1AOT F;  2KK6 A;  1KC2 A;  1A07 A;  2EYY A;  2AOA A;  1O47 A;  2L3T A;  1A08 A;  5AUL A;  3OV1 A;  5KAZ A;  1YVH A;  1FBV A;  2XP1 A;  5BO4 A;  1M61 A;  3UYO A;  3QWX X;  1HCT B;  1NZV A;  3VRR A;  1RQQ C;  1O4Q A;  1JYQ A;  4GWF A;  3MXY A;  2HUW A;  4K2R A;  2DCR A;  1CSY A;  1LCK A;  3HHM B;  1O4P A;  1R1Q A;  2EO3 A;  4NWF A;  4OHI A;  4EY0 A;  2HMH A;  3S9K A;  2DLY A;  1G83 A;  4X6S A;  3BUN B;  5GJI A;  2KNO A;  1O4D A;  2Y1N A;  3PSK A;  1GHU A;  1O46 A;  5J3X A;  3BUO B;  1CWD L;  3QWY A;  1QAD A;  1R1P A;  4OHE A;  2K7A B;  1BFJ A;  3TL0 A;  3US4 A;  1F2F A;  1AOU F;  2CIA A;  2HDX A;  1CJ1 A;  2QMS A;  1JWO A;  1Y57 A;  4LUE A;  1SPR A;  2ROR A;  2EYV A;  2EKX A;  1O4E A;  1SHB A;  3IMD A;  1O4L A;  1BLJ A;  4K11 A;  1FYR A;  4TZI A;  2ECD A;  1KA7 A;  1QG1 E;  4NWG A;  5AXI A;  4JGH A;  2IUG A;  1BHF A;  3VRO A;  3PS5 A;  3UF4 A;  5CDW A;  1BMB A;  5DC0 B;  3GQI B;  1AYC A;  1BM2 A;  2ABL A;  2LQW A;  3BUW B;  1O4C A;  4H1O A;  2BBU A;  1BKM A;  4U17 A;  3S8O A;  2MRK A;  1BF5 A;  5EEQ A;  1O4N A;  2Y1M A;  1JYR A;  1LCJ A;  5HKY A;  1O4G A;  1SPS A;  2YU7 A;  4JEG A;  2DLZ A;  2C0I A;  2FO0 A;  3GXW A;  1XA6 A;  1UUR A;  2CR4 A;  1I3Z A;  5I6V A;  2PNB A;  4JE4 A;  3VS6 A;  1A09 A;  1SKJ A;  5D0J A;  3OB2 B;  1HCS B;  3K2T A;  3S8L A;  2C0T A;  2EU0 A;  2YSX A;  1O4F A;  1A81 A;  1K9A A;  2LNX A;  3NHN A;  1O4R A;  1RPY A;  1A1B A;  4DGP A;  1O42 A;  1OPL A;  4OHD A;  2CI9 A;  4GPL B;  2CI8 A;  2L4K A;  4F5A A;  1IS0 A;  2JYQ A;  3S8N A;  1O4A A;  2PNA A;  2C0O A;  2CRH A;  5EEL A;  2C9W A;  3M7F A;  1LKK A;  4D8K A;  1Z3K A;  4P9Z A;  2Y3A B;  2OQ1 A;  3GXX A;  1A1A A;  3OP0 A;  1BHH A;  2GSB A;  5EG3 B;  2IZV A;  1FMK A;  1X27 A;  1UUS A;  2IUI A;  1O4O A;  1O4K A;  1MIL A;  1FBZ A;  1MW4 A;  2DM0 A;  1LUI A;  5EHR A;  1AYD A;  2EL8 A;  1QCF A;  4E68 A;  5DF6 A;  4H34 A;  1BFI A;  1A1C A;  2RVF A;  1GRI A;  1NZL A;  1LUM A;  1RJA A;  2LQN A;  4P9V A;  3T04 A;  4K45 A;  3N84 A;  3LYV A;  3OVE A;  3N7Y A;  3VS7 A;  3KFJ A;  3VRP A;  3PLF B;  2PLE A;  1OO4 A;  1IJR A;  3TKZ A;  4DGX A;  1O4M A;  1D4W A;  3VS0 A;  3ZNI A;  5DC4 A;  2CBL A;  3C7I A;  3K2M A;  1JU5 A;  1OPK A;  3VS3 A;  2SRC A;  1KA6 A;  3PSJ A;  2AUG A;  1AD5 A;  1ZFP E;  3BUX B;  3OB1 B;  3VS5 A;  2AOB A;  4OHL A;  1CSZ A;  5GJH A;  4F5B A;  1KSW A;  1R1S A;  1NRV A;  2LNW A;  4FBN A;  1WQU A;  1AB2 A;  4FL3 A;  2MRJ A;  4WWQ A;  1O49 A;  1H9O A;  2B3O A;  1O4B A;  4EIH A;  3VRN A;  1BHH B;  5EHP A;  1D4T A;  1X6C A;  2MQI A;  1O41 A;  4GL9 E;  1LUN A;  2HCK A;  2VIF A;  2RMX A;  1OO3 A; 
#chains in the Genus database with same CATH homology
 3VRY A;  1FU6 A;  5DC9 A;  1YVL A;  3BKB A;  2H46 E;  2EYZ A;  3CD3 A;  3CWG A;  2DX0 A;  1O4J A;  4ROJ A;  3PQZ A;  1B47 A;  1O4I A;  4E93 A;  3WA4 A;  5IBS A;  1A1E A;  2H8H A;  1O45 A;  4LUD A;  2LCT A;  1BLK A;  2DVJ A;  3VRQ A;  1LKL A;  3IN8 A;  4FL2 A;  3CBL A;  1FU5 A;  4M4Z A;  4XZ1 A;  1X0N A;  3EAC A;  2IUH A;  5IBM A;  1Y1U A;  3IN7 A;  3VRZ A;  1O48 A;  5HKZ A;  2L6K A;  2GE9 A;  1AYA A;  2CS0 A;  2ETZ A;  3HCK A;  2MK2 A;  4XZ0 A;  4A4C A;  1LUK A;  3PFV A;  4K44 A;  3HIZ B;  2EOB A;  3VS1 A;  5HKW A;  1JYU A;  3MAZ A;  2K79 B;  1TCE A;  1BG1 A;  3VGO A;  1F1W A;  2OZO A;  2PTK A;  3N8M A;  2HDV A;  2SHP A;  1SHD A;  4OHH A;  2MC1 A;  1FHS A;  3EAZ A;  4U1P A;  1BKL A;  4QSY A;  3VS4 A;  3BUM B;  1M27 A;  3PJP A;  1P13 A;  1O43 A;  3IMJ A;  1D1Z A;  2FCI A;  4F59 A;  3CXL A;  2EO6 A;  1AYB A;  1PIC A;  3MXC A;  1TZE E;  1SHA A;  2PLD A;  1CWE A;  3VS2 A;  4A4B A;  2RSY A;  1O4H A;  4L1B B;  2H5K A;  1O44 A;  1AOT F;  2KK6 A;  1KC2 A;  1A07 A;  2EYY A;  2AOA A;  1O47 A;  2L3T A;  1A08 A;  5AUL A;  3OV1 A;  5KAZ A;  1YVH A;  1FBV A;  2XP1 A;  5BO4 A;  1M61 A;  3UYO A;  3QWX X;  1HCT B;  1NZV A;  3VRR A;  1RQQ C;  1O4Q A;  1JYQ A;  4GWF A;  3MXY A;  2HUW A;  4K2R A;  2DCR A;  1CSY A;  1LCK A;  3HHM B;  1O4P A;  1R1Q A;  2EO3 A;  4NWF A;  4OHI A;  4EY0 A;  2HMH A;  3S9K A;  2DLY A;  1G83 A;  4X6S A;  3BUN B;  5GJI A;  2KNO A;  1O4D A;  2Y1N A;  3PSK A;  1GHU A;  1O46 A;  5J3X A;  3BUO B;  1CWD L;  3QWY A;  1QAD A;  1R1P A;  4OHE A;  2K7A B;  1BFJ A;  3TL0 A;  3US4 A;  1F2F A;  1AOU F;  2CIA A;  2HDX A;  1CJ1 A;  2QMS A;  1JWO A;  1Y57 A;  4LUE A;  1SPR A;  2ROR A;  2EYV A;  2EKX A;  1O4E A;  1SHB A;  3IMD A;  1O4L A;  1BLJ A;  4K11 A;  1FYR A;  4TZI A;  2ECD A;  1KA7 A;  1QG1 E;  4NWG A;  5AXI A;  4JGH A;  2IUG A;  1BHF A;  3VRO A;  3PS5 A;  3UF4 A;  5CDW A;  1BMB A;  5DC0 B;  3GQI B;  1AYC A;  1BM2 A;  2ABL A;  2LQW A;  3BUW B;  1O4C A;  4H1O A;  2BBU A;  1BKM A;  4U17 A;  3S8O A;  2MRK A;  1BF5 A;  5EEQ A;  1O4N A;  2Y1M A;  1JYR A;  1LCJ A;  5HKY A;  1O4G A;  1SPS A;  2YU7 A;  4JEG A;  2DLZ A;  2C0I A;  2FO0 A;  3GXW A;  1XA6 A;  1UUR A;  2CR4 A;  1I3Z A;  5I6V A;  2PNB A;  4JE4 A;  3VS6 A;  1A09 A;  1SKJ A;  5D0J A;  3OB2 B;  1HCS B;  3S8L A;  2C0T A;  2EU0 A;  2YSX A;  1O4F A;  1A81 A;  1K9A A;  2LNX A;  3NHN A;  1O4R A;  1RPY A;  1A1B A;  4DGP A;  1O42 A;  1OPL A;  4OHD A;  2CI9 A;  4GPL B;  2CI8 A;  2L4K A;  4F5A A;  1IS0 A;  2JYQ A;  3S8N A;  1O4A A;  2PNA A;  2C0O A;  2CRH A;  5EEL A;  2C9W A;  3M7F A;  1LKK A;  4D8K A;  1Z3K A;  4P9Z A;  2Y3A B;  2OQ1 A;  3GXX A;  1A1A A;  3OP0 A;  1BHH A;  2GSB A;  5EG3 B;  2IZV A;  1FMK A;  1X27 A;  1UUS A;  2IUI A;  1O4O A;  1O4K A;  1MIL A;  1FBZ A;  1MW4 A;  2DM0 A;  1LUI A;  5EHR A;  1AYD A;  2EL8 A;  1QCF A;  4E68 A;  5DF6 A;  4H34 A;  1BFI A;  1A1C A;  2RVF A;  1GRI A;  1NZL A;  1LUM A;  1RJA A;  2LQN A;  4P9V A;  3T04 A;  4K45 A;  3N84 A;  3OVE A;  3N7Y A;  3VS7 A;  3KFJ A;  3VRP A;  3PLF B;  2PLE A;  1OO4 A;  1IJR A;  3TKZ A;  4DGX A;  1O4M A;  1D4W A;  3VS0 A;  3ZNI A;  5DC4 A;  2CBL A;  3C7I A;  3K2M A;  1JU5 A;  1OPK A;  3VS3 A;  2SRC A;  1KA6 A;  3PSJ A;  2AUG A;  1AD5 A;  1ZFP E;  3BUX B;  3OB1 B;  3VS5 A;  2AOB A;  4OHL A;  1CSZ A;  5GJH A;  4F5B A;  1KSW A;  1R1S A;  1NRV A;  2LNW A;  4FBN A;  1WQU A;  1AB2 A;  4FL3 A;  2MRJ A;  4WWQ A;  1O49 A;  1H9O A;  2B3O A;  1O4B A;  4EIH A;  3VRN A;  1BHH B;  5EHP A;  1D4T A;  1X6C A;  2MQI A;  1O41 A;  4GL9 E;  1LUN A;  2HCK A;  2VIF A;  2RMX A;  1OO3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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