4XWXA

Crystal structure of the ptb domain of shc
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
167
structure length
160
Chain Sequence
SMGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGASRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the PTB domain of SHC
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords SHC-transforming protein 1
total genus 43
structure length 160
sequence length 167
ec nomenclature
pdb deposition date 2015-01-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 4xwxA00
2K2JA 4MK0A 4GPTB 3KRWA 4DX8A 1FOEA 2YS3A 2YSZA 4HAVB 4CHJA 4L6EA 2EC1A 2GS0A 1U2BA 2FJLA 4KVGB 2QKLA 1QC6A 3FM8C 2CODA 3PEGA 1NU2A 4DX90 3QWMA 2DLWA 2OTXA 3LJUX 4HAZB 2CRFA 3DXCA 4PNKA 4EKUA 1DROA 5JLJB 3X23A 3D8EA 2M38A 1PLSA 4B6HA 3UZTA 2IYBA 1FHOA 3PVUA 1ZC4B 4HAXB 1ZSQA 3V5WA 3SNHA 5C5BB 2VSZA 3WA0A 3CIKA 1V89A 2RSGA 4A6HA 2LYDA 1TJ6A 3BINA 2UVMA 4KHOA 2GJYA 5D3XA 1UEFA 4HB0B 4C0AA 5DH9B 3PVLA 5CLLB 1E5WA 2ELBA 4PQ0A 3G9WA 3PVWA 2DYNA 3ZVRA 2D11A 4F7HA 1MK9B 2I5CA 2K00A 2YT0A 3SUZA 1Z87A 5DHAB 1FHWA 1AWEA 2G35A 1X86A 5D27A 5KQ4A 2RNRB 4Z2MB 4F7GA 1WJ1A 3TFMA 3QIJA 3TO1A 4GXBA 3AJ4A 2DHJA 4YL8A 3DXEA 2I5FA 1SHCA 5KCVA 4Z2NA 1MK7B 1V5MA 5HE2A 2UZRA 2LG1A 2DKPA 2HE7A 1FGZA 1LW3A 4H8SA 2Y7BA 2D9VA 4TYZA 4HAYB 1J0WA 4HB4B 5FI0A 4D0NB 1MAIA 3ULCA 1EGXA 1FAOA 3AU4A 3VOQA 1DBHA 1WG7A 3A8QA 1IRSA 2J59M 4HATB 3GYPA 4NSWA 1XKEA 1X1GA 5J3TA 5J3QA 3A8PA 2NMBA 1OMWA 5GOWB 3WYFB 4YONA 5L81A 2DN6A 3PG7A 3QBVB 4K81A 2YS1A 1PMSA 3P6AA 1UNPA 4Y94A 1DDMA 5JP4A 1FGYA 2YS5A 1W1DA 1OQNA 3KSYA 4BBKA 1GC6A 2DFKA 2D4QA 3M1IB 5J3YA 3FEHA 4HHVA 3SO6A 1LB1A 4HB2B 1BTKA 4IFSA 5HE0A 1P5TA 5CLQB 2CY5A 3BJIA 2H7DA 3D8FA 1MIZB 5LONB 2VRWB 2OQBA 2RVBB 4HDQA 1ZC3B 1I7AA 2Z0OA 4HAUB 4WJ7A 2DHIA 2R0DA 1NI2A 2W2XC 1DYNA 1P6SA 2XQNM 2E2XA 4IOYX 2COAA 1DDWA 1J19A 1NTVA 1XX0A 1W1HA 2GCLA 2KUPA 4WVFB 2HTHB 2BCJA 3KY9A 3OANA 5HE3A 1DDVA 4DBBA 1OY2A 5D3WA 3HW2B 2Z0PA 3ODOA 3PZDA 2CAYA 1AQCA 2I1JA 2YF0A 2P0DA 5DI9B 1UPRA 3AU5A 2AL6A 1V61A 1K5DB 4HDOA 4GMXB 3O96A 1WGUA 1Q67A 1B55A 1XR0B 3MDBC 2D9XA 2YRYA 2H7EA 4K17A 4ZRJA 5EFXA 1WJMA 2KGXB 4GZUA 2YT1A 3F5RA 2D9WA 1Y5OA 2IFSA 2R09A 3GYOA 2GCJA 4IAPA 1ZM0A 2D9YA 5D3YA 1RRPB 1SGHA 4A6FB 1NTYA 1V5UA 3RCPA 3SV1A 3TW1A 3D8DA 3F0WA 3PP2A 2K2UA 1PFJA 1P3RA 4GMVA 4ZRIA 3N7CA 5JHGA 2DA0A 1V5PA 3ODWA 1H10A 2RUKB 1H4RA 2M14A 4A5KA 1GG3A 1QQGA 2P0HA 4XWXA 3U7DA 1KI1B 3NSUA 2RGNB 1UNQA 2UZSA 2COFA 2V76A 3MPXA 2KCJA 3HK0A 5KQ1A 2MFQA 2LOZA 2EJ8A 2W2XD 2AEHA 1FHXA 1N3HA 4HB3B 1UNRA 2P8VA 3HQCA 2D10A 4GN1A 5JHHA 2DYQA 1W1GA 2ROZB 2X18A 3KRXA 3P7ZA 2Y8GA 1U29A 4DXAB 2DTCA 2QKMA 5C79A 3KZ1A 4NY0A 4A6KA 3FSSA 3ODXA 5HE1A 3VIAA 2MDXA 1U5FA 2DKQA 5C5BA 4ZRKA 5C6RA 5FI1A 2DX1A 2L2IA 3CXBB 2Q13A 3TCAA 3A98B 2J0MA 2JP2A 1V88A 2ZPYA 2Z0QA 2N23A 2DHKA 3TVVA 1XD4A 2ROVA 1WVHA 2N0YA 5C16A 1TXDA 2LOXA 1U5DA 4K2OA 1XODA 1XCGA 1M7EA 2ADZA 4CYEA 1K5GB 2J0JA 2D9ZA 1KZ7A 4P7IA 4EJNA 1ISNA 2L1CA 4KHBB 2MKRA 2J0KA 2DX5A 1TQZA 2COCA 1GC7A 1X11A 2Y8FA 2EMSA 1I2HA 2VKIA 4WSFA 1MPHA 1BWNA 4A6FA 3ZDTA 4TKNA 2MWNB 2I1KA 3IVFA 4KAXB 1X1FA 5DHFB 1EAZA 1BAKA 2YVCA 2LULA 1KZGA 2D2QA 3PSCA 4KHAA 4MY6A 2NZ8B 2PZ1A 2ELAA 2EMTA 4K2PA 1FB8A 1WI1A 1EVHA 1MKEA 1M7RA 1EF1A 5LOPB 1RJ2A 4MT7A 2LKOA 4EMOA 1ZVRA 2RLOA 3DXDA 3T06A 3U8ZA 1U27A 1UPQA 4F7UP 2P0FA 1U5GA 4HAWB 1MIXA 3ML4A 3ULBA 1U5EA 1Y19B 5D3VA 2W2WA 3SYXA 5DIFB 1X05A 4CHMA 1BTNA 1WGQA 2CY4A
chains in the Genus database with same CATH superfamily
2K2JA 4MK0A 4GPTB 4HSIA 3KRWA 4DX8A 1FOEA 2YS3A 2YSZA 4HAVB 4CHJA 4L6EA 2EC1A 2K8EA 2GS0A 1U2BA 2FJLA 4KVGB 2QKLA 1QC6A 3FM8C 2CODA 3PEGA 1NU2A 2ZKMX 4DX90 3QWMA 2DLWA 2OTXA 3LJUX 4HAZB 2CRFA 2K49A 3DXCA 4PNKA 3NWFA 2KIEA 3U12A 4EKUA 1DROA 5JLJB 3X23A 3A58A 3D8EA 2M38A 1PLSA 4B6HA 2R2YA 3UZTA 2IYBA 1FHOA 3PVUA 1ZC4B 4HAXB 1ZSQA 3V5WA 3SNHA 5C5BB 2VSZA 3WA0A 3CIKA 1V89A 2RSGA 4A6HA 2LYDA 1TJ6A 3BINA 2UVMA 4KHOA 2GJYA 5D3XA 1UEFA 4HB0B 4C0AA 3OHMB 5DH9B 3PVLA 5CLLB 1E5WA 2ELBA 4PQ0A 3G9WA 3PVWA 2DYNA 3ZVRA 2D11A 4F7HA 1MK9B 2I5CA 2K00A 2YT0A 3SUZA 1Z87A 5DHAB 1FHWA 1AWEA 2G35A 1X86A 5D27A 5KQ4A 2RNRB 4Z2MB 4F7GA 1WJ1A 3TFMA 3QIJA 3TO1A 2KUQA 2GUMA 4GXBA 3AJ4A 2DHJA 4YL8A 3DXEA 2I5FA 1SHCA 5KCVA 4Z2NA 1MK7B 4QJ5B 1V5MA 5HE2A 2UZRA 2LG1A 3HSAA 2DKPA 2HE7A 1FGZA 1LW3A 3NW8A 4H8SA 3HIEA 2Y7BA 2D9VA 4TYZA 4HAYB 1J0WA 4HB4B 5FI0A 4D0NB 1MAIA 3ULCA 1EGXA 1FAOA 3AU4A 3VOQA 1DBHA 1WG7A 3A8QA 1IRSA 2J59M 4HATB 3GYPA 4NSWA 1XKEA 1X1GA 5J3TA 5J3QA 3A8PA 2NMBA 1OMWA 5GOWB 3WYFB 4YONA 5L81A 2DN6A 4QXAB 3PG7A 3QBVB 4K81A 4QJ4B 2YS1A 1PMSA 3P6AA 1UNPA 4Y94A 1DDMA 5JP4A 1FGYA 2YS5A 1W1DA 1OQNA 3KSYA 4BBKA 1GC6A 2DFKA 2D4QA 3M1IB 5J3YA 3NWDA 3FEHA 3B77A 4D6WA 4HHVA 3SO6A 1LB1A 4HB2B 1BTKA 5M4YB 4IFSA 5HE0A 1P5TA 5CLQB 2CY5A 3BJIA 2H7DA 3D8FA 1MIZB 5LONB 2VRWB 2OQBA 2RVBB 4HDQA 1ZC3B 1I7AA 2Z0OA 4HAUB 4WJ7A 2DHIA 2R0DA 1NI2A 2W2XC 1DYNA 1P6SA 2XQNM 2E2XA 4IOYX 2COAA 1DDWA 1J19A 1NTVA 1XX0A 1W1HA 2GCLA 4KHBA 2KUPA 4WVFB 2HTHB 2BCJA 3KY9A 4GNKB 3OANA 5HE3A 1DDVA 4OSNA 4DBBA 1OY2A 5D3WA 3HW2B 2Z0PA 3ODOA 2Z13A 3PZDA 2CAYA 1AQCA 2I1JA 2YF0A 2P0DA 5DI9B 1UPRA 3AU5A 2AL6A 1V61A 1K5DB 4HDOA 4GMXB 4CSQA 3O96A 1WGUA 4QJ3B 1Q67A 1B55A 1XR0B 3MDBC 2D9XA 2YRYA 2H7EA 4K17A 4ZRJA 5EFXA 1WJMA 2KGXB 4L1RA 2RRFA 2YT1A 3F5RA 4GZUA 2D9WA 1Y5OA 5LG4B 2IFSA 2R09A 3GYOA 2GCJA 4IAPA 1ZM0A 2D9YA 5D3YA 1RRPB 1SGHA 4A6FB 1NTYA 1V5UA 3RCPA 3SV1A 3TW1A 3D8DA 3F0WA 3PP2A 2K2UA 1PFJA 1P3RA 4GMVA 4ZRIA 3N7CA 3FVCA 5JHGA 4OT1A 2DA0A 1V5PA 3ODWA 1H10A 2RUKB 1H4RA 2M14A 1T77A 1GG3A 4A5KA 1QQGA 2P0HA 4XWXA 3U7DA 1KI1B 3NSUA 5I2SA 2RGNB 1UNQA 2UZSA 1ZYIA 2COFA 2V76A 3MPXA 2KCJA 3HK0A 5KQ1A 2MFQA 2LOZA 2EJ8A 2W2XD 2AEHA 1FHXA 1N3HA 4HB3B 2Z59A 1UNRA 2P8VA 3HQCA 2D10A 4GN1A 5JHHA 2DYQA 1W1GA 2ROZB 2X18A 2YT2A 3KRXA 3P7ZA 2Y8GA 1U29A 4DXAB 2DTCA 2QKMA 5C79A 3KZ1A 4NY0A 4A6KA 3FSSA 3ODXA 5HE1A 3VIAA 2MDXA 2KR0A 1U5FA 2DKQA 5C5BA 5IRSA 4ZRKA 5C6RA 5FI1A 5I2MA 2DX1A 2L2IA 3CXBB 2Q13A 2Z4DA 3TCAA 3A98B 2J0MA 2JP2A 1V88A 2ZPYA 2Z0QA 2N23A 2DHKA 2Z14A 1MI1A 3TVVA 1XD4A 2ROVA 1WVHA 2N0YA 5C16A 1TXDA 2LOXA 1U5DA 4K2OA 1XODA 1XCGA 1M7EA 2ADZA 4CYEA 1K5GB 2J0JA 2D9ZA 1KZ7A 4P7IA 4EJNA 1ISNA 2L1CA 4KHBB 2MKRA 2J0KA 2DX5A 1TQZA 2COCA 1GC7A 4DIXA 1X11A 2Y8FA 2EMSA 1I2HA 2VKIA 4WSFA 1MPHA 3DCXA 1BWNA 4A6FA 3ZDTA 4GOUA 4TKNA 2MWNB 2I1KA 2FJUB 3IVFA 4KAXB 1X1FA 5DHFB 1EAZA 1BAKA 2YVCA 2LULA 1KZGA 2D2QA 3PSCA 4KHAA 4MY6A 2NZ8B 2PZ1A 2ELAA 2EMTA 4K2PA 1FB8A 1WI1A 1EVHA 1MKEA 1M7RA 1EF1A 5LOPB 1RJ2A 4MT7A 2LKOA 4EMOA 1ZVRA 2KIGA 2RLOA 3DXDA 3T06A 3U8ZA 1U27A 1UPQA 4F7UP 2P0FA 1U5GA 4HAWB 2NBVA 1MIXA 3ML4A 3ULBA 1U5EA 1Y19B 5D3VA 2W2WA 3SYXA 3NWAA 5DIFB 1X05A 4CHMA 1BTNA 1WGQA 2CY4A
chains in the Genus database with same CATH topology
2K2JA 4MK0A 4GPTB 3KRWA 4DX8A 1FOEA 2YS3A 2YSZA 4HAVB 4CHJA 4L6EA 2EC1A 2GS0A 1U2BA 2FJLA 4KVGB 2QKLA 1QC6A 3FM8C 2CODA 3PEGA 1NU2A 4DX90 3QWMA 2DLWA 2OTXA 3LJUX 4HAZB 2CRFA 3DXCA 4PNKA 4EKUA 1DROA 5JLJB 3X23A 3D8EA 2M38A 1PLSA 4B6HA 3UZTA 2IYBA 1FHOA 3PVUA 1ZC4B 4HAXB 1ZSQA 3V5WA 3SNHA 5C5BB 2VSZA 3WA0A 3CIKA 1V89A 2RSGA 4A6HA 2LYDA 1TJ6A 3BINA 2UVMA 4KHOA 2GJYA 5D3XA 1UEFA 4HB0B 4C0AA 5DH9B 3PVLA 5CLLB 1E5WA 2ELBA 4PQ0A 3G9WA 3PVWA 2DYNA 3ZVRA 2D11A 4F7HA 1MK9B 2I5CA 2K00A 2YT0A 3SUZA 1Z87A 5DHAB 1FHWA 1AWEA 2G35A 1X86A 5D27A 5KQ4A 2RNRB 4Z2MB 4F7GA 1WJ1A 3TFMA 3QIJA 3TO1A 4GXBA 3AJ4A 2DHJA 4YL8A 3DXEA 2I5FA 1SHCA 5KCVA 4Z2NA 1MK7B 1V5MA 5HE2A 2UZRA 2LG1A 2DKPA 2HE7A 1FGZA 1LW3A 4H8SA 2Y7BA 2D9VA 4TYZA 4HAYB 1J0WA 4HB4B 5FI0A 4D0NB 1MAIA 3ULCA 1EGXA 1FAOA 3AU4A 3VOQA 1DBHA 1WG7A 3A8QA 1IRSA 2J59M 4HATB 3GYPA 4NSWA 1XKEA 1X1GA 5J3TA 5J3QA 3A8PA 2NMBA 1OMWA 5GOWB 3WYFB 4YONA 5L81A 2DN6A 3PG7A 3QBVB 4K81A 2YS1A 1PMSA 3P6AA 1UNPA 4Y94A 1DDMA 5JP4A 1FGYA 2YS5A 1W1DA 1OQNA 3KSYA 4BBKA 1GC6A 2DFKA 2D4QA 3M1IB 5J3YA 3FEHA 4HHVA 3SO6A 1LB1A 4HB2B 1BTKA 4IFSA 5HE0A 1P5TA 5CLQB 2CY5A 3BJIA 2H7DA 3D8FA 1MIZB 5LONB 2VRWB 2OQBA 2RVBB 4HDQA 1ZC3B 1I7AA 2Z0OA 4HAUB 4WJ7A 2DHIA 2R0DA 1NI2A 2W2XC 1DYNA 1P6SA 2XQNM 2E2XA 4IOYX 2COAA 1DDWA 1J19A 1NTVA 1XX0A 1W1HA 2GCLA 2KUPA 4WVFB 2HTHB 2BCJA 3KY9A 3OANA 5HE3A 1DDVA 4DBBA 1OY2A 5D3WA 3HW2B 2Z0PA 3ODOA 3PZDA 2CAYA 1AQCA 2I1JA 2YF0A 2P0DA 5DI9B 1UPRA 3AU5A 2AL6A 1V61A 1K5DB 4HDOA 4GMXB 3O96A 1WGUA 1Q67A 1B55A 1XR0B 3MDBC 2D9XA 2YRYA 2H7EA 4K17A 4ZRJA 5EFXA 1WJMA 2KGXB 4GZUA 2YT1A 3F5RA 2D9WA 1Y5OA 2IFSA 2R09A 3GYOA 2GCJA 4IAPA 1ZM0A 2D9YA 5D3YA 1RRPB 1SGHA 4A6FB 1NTYA 1V5UA 3RCPA 3SV1A 3TW1A 3D8DA 3F0WA 3PP2A 2K2UA 1PFJA 1P3RA 4GMVA 4ZRIA 3N7CA 5JHGA 2DA0A 1V5PA 3ODWA 1H10A 2RUKB 1H4RA 2M14A 4A5KA 1GG3A 1QQGA 2P0HA 4XWXA 3U7DA 1KI1B 3NSUA 2RGNB 1UNQA 2UZSA 2COFA 2V76A 3MPXA 2KCJA 3HK0A 5KQ1A 2MFQA 2LOZA 2EJ8A 2W2XD 2AEHA 1FHXA 1N3HA 4HB3B 1UNRA 2P8VA 3HQCA 2D10A 4GN1A 5JHHA 2DYQA 1W1GA 2ROZB 2X18A 3KRXA 3P7ZA 2Y8GA 1U29A 4DXAB 2DTCA 2QKMA 5C79A 3KZ1A 4NY0A 4A6KA 3FSSA 3ODXA 5HE1A 3VIAA 2MDXA 1U5FA 2DKQA 5C5BA 4ZRKA 5C6RA 5FI1A 2DX1A 2L2IA 3CXBB 2Q13A 3TCAA 3A98B 2J0MA 2JP2A 1V88A 2ZPYA 2Z0QA 2N23A 2DHKA 3TVVA 1XD4A 2ROVA 1WVHA 2N0YA 5C16A 1TXDA 2LOXA 1U5DA 4K2OA 1XODA 1XCGA 1M7EA 2ADZA 4CYEA 1K5GB 2J0JA 2D9ZA 1KZ7A 4P7IA 4EJNA 1ISNA 2L1CA 4KHBB 2MKRA 2J0KA 2DX5A 1TQZA 2COCA 1GC7A 1X11A 2Y8FA 2EMSA 1I2HA 2VKIA 4WSFA 1MPHA 1BWNA 4A6FA 3ZDTA 4TKNA 2MWNB 2I1KA 3IVFA 4KAXB 1X1FA 5DHFB 1EAZA 1BAKA 2YVCA 2LULA 1KZGA 2D2QA 3PSCA 4KHAA 4MY6A 2NZ8B 2PZ1A 2ELAA 2EMTA 4K2PA 1FB8A 1WI1A 1EVHA 1MKEA 1M7RA 1EF1A 5LOPB 1RJ2A 4MT7A 2LKOA 4EMOA 1ZVRA 2RLOA 3DXDA 3T06A 3U8ZA 1U27A 1UPQA 4F7UP 2P0FA 1U5GA 4HAWB 1MIXA 3ML4A 3ULBA 1U5EA 1Y19B 5D3VA 2W2WA 3SYXA 5DIFB 1X05A 4CHMA 1BTNA 1WGQA 2CY4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2K2J A;  4MK0 A;  4GPT B;  3KRW A;  4DX8 A;  1FOE A;  2YS3 A;  2YSZ A;  4HAV B;  4CHJ A;  4L6E A;  2EC1 A;  2GS0 A;  1U2B A;  2FJL A;  4KVG B;  2QKL A;  1QC6 A;  3FM8 C;  2COD A;  3PEG A;  1NU2 A;  4DX9 0;  3QWM A;  2DLW A;  2OTX A;  3LJU X;  4HAZ B;  2CRF A;  3DXC A;  4PNK A;  4EKU A;  1DRO A;  5JLJ B;  3X23 A;  3D8E A;  2M38 A;  1PLS A;  4B6H A;  3UZT A;  2IYB A;  1FHO A;  3PVU A;  1ZC4 B;  4HAX B;  1ZSQ A;  3V5W A;  3SNH A;  5C5B B;  2VSZ A;  3WA0 A;  3CIK A;  1V89 A;  2RSG A;  4A6H A;  2LYD A;  1TJ6 A;  3BIN A;  2UVM A;  4KHO A;  2GJY A;  5D3X A;  1UEF A;  4HB0 B;  4C0A A;  5DH9 B;  3PVL A;  5CLL B;  1E5W A;  2ELB A;  4PQ0 A;  3G9W A;  3PVW A;  2DYN A;  3ZVR A;  2D11 A;  4F7H A;  1MK9 B;  2I5C A;  2K00 A;  2YT0 A;  3SUZ A;  1Z87 A;  5DHA B;  1FHW A;  1AWE A;  2G35 A;  1X86 A;  5D27 A;  5KQ4 A;  2RNR B;  4Z2M B;  4F7G A;  1WJ1 A;  3TFM A;  3QIJ A;  3TO1 A;  4GXB A;  3AJ4 A;  2DHJ A;  4YL8 A;  3DXE A;  2I5F A;  1SHC A;  5KCV A;  4Z2N A;  1MK7 B;  1V5M A;  5HE2 A;  2UZR A;  2LG1 A;  2DKP A;  2HE7 A;  1FGZ A;  1LW3 A;  4H8S A;  2Y7B A;  2D9V A;  4TYZ A;  4HAY B;  1J0W A;  4HB4 B;  5FI0 A;  4D0N B;  1MAI A;  3ULC A;  1EGX A;  1FAO A;  3AU4 A;  3VOQ A;  1DBH A;  1WG7 A;  3A8Q A;  1IRS A;  2J59 M;  4HAT B;  3GYP A;  4NSW A;  1XKE A;  1X1G A;  5J3T A;  5J3Q A;  3A8P A;  2NMB A;  1OMW A;  5GOW B;  3WYF B;  4YON A;  5L81 A;  2DN6 A;  3PG7 A;  3QBV B;  4K81 A;  2YS1 A;  1PMS A;  3P6A A;  1UNP A;  4Y94 A;  1DDM A;  5JP4 A;  1FGY A;  2YS5 A;  1W1D A;  1OQN A;  3KSY A;  4BBK A;  1GC6 A;  2DFK A;  2D4Q A;  3M1I B;  5J3Y A;  3FEH A;  4HHV A;  3SO6 A;  1LB1 A;  4HB2 B;  1BTK A;  4IFS A;  5HE0 A;  1P5T A;  5CLQ B;  2CY5 A;  3BJI A;  2H7D A;  3D8F A;  1MIZ B;  5LON B;  2VRW B;  2OQB A;  2RVB B;  4HDQ A;  1ZC3 B;  1I7A A;  2Z0O A;  4HAU B;  4WJ7 A;  2DHI A;  2R0D A;  1NI2 A;  2W2X C;  1DYN A;  1P6S A;  2XQN M;  2E2X A;  4IOY X;  2COA A;  1DDW A;  1J19 A;  1NTV A;  1XX0 A;  1W1H A;  2GCL A;  2KUP A;  4WVF B;  2HTH B;  2BCJ A;  3KY9 A;  3OAN A;  5HE3 A;  1DDV A;  4DBB A;  1OY2 A;  5D3W A;  3HW2 B;  2Z0P A;  3ODO A;  3PZD A;  2CAY A;  1AQC A;  2I1J A;  2YF0 A;  2P0D A;  5DI9 B;  1UPR A;  3AU5 A;  2AL6 A;  1V61 A;  1K5D B;  4HDO A;  4GMX B;  3O96 A;  1WGU A;  1Q67 A;  1B55 A;  1XR0 B;  3MDB C;  2D9X A;  2YRY A;  2H7E A;  4K17 A;  4ZRJ A;  5EFX A;  1WJM A;  2KGX B;  4GZU A;  2YT1 A;  3F5R A;  2D9W A;  1Y5O A;  2IFS A;  2R09 A;  3GYO A;  2GCJ A;  4IAP A;  1ZM0 A;  2D9Y A;  5D3Y A;  1RRP B;  1SGH A;  4A6F B;  1NTY A;  1V5U A;  3RCP A;  3SV1 A;  3TW1 A;  3D8D A;  3F0W A;  3PP2 A;  2K2U A;  1PFJ A;  1P3R A;  4GMV A;  4ZRI A;  3N7C A;  5JHG A;  2DA0 A;  1V5P A;  3ODW A;  1H10 A;  2RUK B;  1H4R A;  2M14 A;  4A5K A;  1GG3 A;  1QQG A;  2P0H A;  4XWX A;  3U7D A;  1KI1 B;  3NSU A;  2RGN B;  1UNQ A;  2UZS A;  2COF A;  2V76 A;  3MPX A;  2KCJ A;  3HK0 A;  5KQ1 A;  2MFQ A;  2LOZ A;  2EJ8 A;  2W2X D;  2AEH A;  1FHX A;  1N3H A;  4HB3 B;  1UNR A;  2P8V A;  3HQC A;  2D10 A;  4GN1 A;  5JHH A;  2DYQ A;  1W1G A;  2ROZ B;  2X18 A;  3KRX A;  3P7Z A;  2Y8G A;  1U29 A;  4DXA B;  2DTC A;  2QKM A;  5C79 A;  3KZ1 A;  4NY0 A;  4A6K A;  3FSS A;  3ODX A;  5HE1 A;  3VIA A;  2MDX A;  1U5F A;  2DKQ A;  5C5B A;  4ZRK A;  5C6R A;  5FI1 A;  2DX1 A;  2L2I A;  3CXB B;  2Q13 A;  3TCA A;  3A98 B;  2J0M A;  2JP2 A;  1V88 A;  2ZPY A;  2Z0Q A;  2N23 A;  2DHK A;  3TVV A;  1XD4 A;  2ROV A;  1WVH A;  2N0Y A;  5C16 A;  1TXD A;  2LOX A;  1U5D A;  4K2O A;  1XOD A;  1XCG A;  1M7E A;  2ADZ A;  4CYE A;  1K5G B;  2J0J A;  2D9Z A;  1KZ7 A;  4P7I A;  4EJN A;  1ISN A;  2L1C A;  4KHB B;  2MKR A;  2J0K A;  2DX5 A;  1TQZ A;  2COC A;  1GC7 A;  1X11 A;  2Y8F A;  2EMS A;  1I2H A;  2VKI A;  4WSF A;  1MPH A;  1BWN A;  4A6F A;  3ZDT A;  4TKN A;  2MWN B;  2I1K A;  3IVF A;  4KAX B;  1X1F A;  5DHF B;  1EAZ A;  1BAK A;  2YVC A;  2LUL A;  1KZG A;  2D2Q A;  3PSC A;  4KHA A;  4MY6 A;  2NZ8 B;  2PZ1 A;  2ELA A;  2EMT A;  4K2P A;  1FB8 A;  1WI1 A;  1EVH A;  1MKE A;  1M7R A;  1EF1 A;  5LOP B;  1RJ2 A;  4MT7 A;  2LKO A;  4EMO A;  1ZVR A;  2RLO A;  3DXD A;  3T06 A;  3U8Z A;  1U27 A;  1UPQ A;  4F7U P;  2P0F A;  1U5G A;  4HAW B;  1MIX A;  3ML4 A;  3ULB A;  1U5E A;  1Y19 B;  5D3V A;  2W2W A;  3SYX A;  5DIF B;  1X05 A;  4CHM A;  1BTN A;  1WGQ A;  2CY4 A; 
#chains in the Genus database with same CATH topology
 2K2J A;  4MK0 A;  4GPT B;  4HSI A;  3KRW A;  4DX8 A;  1FOE A;  2YS3 A;  2YSZ A;  4HAV B;  4CHJ A;  4L6E A;  2EC1 A;  2K8E A;  2GS0 A;  1U2B A;  2FJL A;  4KVG B;  2QKL A;  1QC6 A;  3FM8 C;  2COD A;  3PEG A;  1NU2 A;  2ZKM X;  4DX9 0;  3QWM A;  2DLW A;  2OTX A;  3LJU X;  4HAZ B;  2CRF A;  2K49 A;  3DXC A;  4PNK A;  3NWF A;  2KIE A;  3U12 A;  4EKU A;  1DRO A;  5JLJ B;  3X23 A;  3A58 A;  3D8E A;  2M38 A;  1PLS A;  4B6H A;  2R2Y A;  3UZT A;  2IYB A;  1FHO A;  3PVU A;  1ZC4 B;  4HAX B;  1ZSQ A;  3V5W A;  3SNH A;  5C5B B;  2VSZ A;  3WA0 A;  3CIK A;  1V89 A;  2RSG A;  4A6H A;  2LYD A;  1TJ6 A;  3BIN A;  2UVM A;  4KHO A;  2GJY A;  5D3X A;  1UEF A;  4HB0 B;  4C0A A;  3OHM B;  5DH9 B;  3PVL A;  5CLL B;  1E5W A;  2ELB A;  4PQ0 A;  3G9W A;  3PVW A;  2DYN A;  3ZVR A;  2D11 A;  4F7H A;  1MK9 B;  2I5C A;  2K00 A;  2YT0 A;  3SUZ A;  1Z87 A;  5DHA B;  1FHW A;  1AWE A;  2G35 A;  1X86 A;  5D27 A;  5KQ4 A;  2RNR B;  4Z2M B;  4F7G A;  1WJ1 A;  3TFM A;  3QIJ A;  3TO1 A;  2KUQ A;  2GUM A;  4GXB A;  3AJ4 A;  2DHJ A;  4YL8 A;  3DXE A;  2I5F A;  1SHC A;  5KCV A;  4Z2N A;  1MK7 B;  4QJ5 B;  1V5M A;  5HE2 A;  2UZR A;  2LG1 A;  3HSA A;  2DKP A;  2HE7 A;  1FGZ A;  1LW3 A;  3NW8 A;  4H8S A;  3HIE A;  2Y7B A;  2D9V A;  4TYZ A;  4HAY B;  1J0W A;  4HB4 B;  5FI0 A;  4D0N B;  1MAI A;  3ULC A;  1EGX A;  1FAO A;  3AU4 A;  3VOQ A;  1DBH A;  1WG7 A;  3A8Q A;  1IRS A;  2J59 M;  4HAT B;  3GYP A;  4NSW A;  1XKE A;  1X1G A;  5J3T A;  5J3Q A;  3A8P A;  2NMB A;  1OMW A;  5GOW B;  3WYF B;  4YON A;  5L81 A;  2DN6 A;  4QXA B;  3PG7 A;  3QBV B;  4K81 A;  4QJ4 B;  2YS1 A;  1PMS A;  3P6A A;  1UNP A;  4Y94 A;  1DDM A;  5JP4 A;  1FGY A;  2YS5 A;  1W1D A;  1OQN A;  3KSY A;  4BBK A;  1GC6 A;  2DFK A;  2D4Q A;  3M1I B;  5J3Y A;  3NWD A;  3FEH A;  3B77 A;  4D6W A;  4HHV A;  3SO6 A;  1LB1 A;  4HB2 B;  1BTK A;  5M4Y B;  4IFS A;  5HE0 A;  1P5T A;  5CLQ B;  2CY5 A;  3BJI A;  2H7D A;  3D8F A;  1MIZ B;  5LON B;  2VRW B;  2OQB A;  2RVB B;  4HDQ A;  1ZC3 B;  1I7A A;  2Z0O A;  4HAU B;  4WJ7 A;  2DHI A;  2R0D A;  1NI2 A;  2W2X C;  1DYN A;  1P6S A;  2XQN M;  2E2X A;  4IOY X;  2COA A;  1DDW A;  1J19 A;  1NTV A;  1XX0 A;  1W1H A;  2GCL A;  4KHB A;  2KUP A;  4WVF B;  2HTH B;  2BCJ A;  3KY9 A;  4GNK B;  3OAN A;  5HE3 A;  1DDV A;  4OSN A;  4DBB A;  1OY2 A;  5D3W A;  3HW2 B;  2Z0P A;  3ODO A;  2Z13 A;  3PZD A;  2CAY A;  1AQC A;  2I1J A;  2YF0 A;  2P0D A;  5DI9 B;  1UPR A;  3AU5 A;  2AL6 A;  1V61 A;  1K5D B;  4HDO A;  4GMX B;  4CSQ A;  3O96 A;  1WGU A;  4QJ3 B;  1Q67 A;  1B55 A;  1XR0 B;  3MDB C;  2D9X A;  2YRY A;  2H7E A;  4K17 A;  4ZRJ A;  5EFX A;  1WJM A;  2KGX B;  4L1R A;  2RRF A;  2YT1 A;  3F5R A;  4GZU A;  2D9W A;  1Y5O A;  5LG4 B;  2IFS A;  2R09 A;  3GYO A;  2GCJ A;  4IAP A;  1ZM0 A;  2D9Y A;  5D3Y A;  1RRP B;  1SGH A;  4A6F B;  1NTY A;  1V5U A;  3RCP A;  3SV1 A;  3TW1 A;  3D8D A;  3F0W A;  3PP2 A;  2K2U A;  1PFJ A;  1P3R A;  4GMV A;  4ZRI A;  3N7C A;  3FVC A;  5JHG A;  4OT1 A;  2DA0 A;  1V5P A;  3ODW A;  1H10 A;  2RUK B;  1H4R A;  2M14 A;  1T77 A;  1GG3 A;  4A5K A;  1QQG A;  2P0H A;  4XWX A;  3U7D A;  1KI1 B;  3NSU A;  5I2S A;  2RGN B;  1UNQ A;  2UZS A;  1ZYI A;  2COF A;  2V76 A;  3MPX A;  2KCJ A;  3HK0 A;  5KQ1 A;  2MFQ A;  2LOZ A;  2EJ8 A;  2W2X D;  2AEH A;  1FHX A;  1N3H A;  4HB3 B;  2Z59 A;  1UNR A;  2P8V A;  3HQC A;  2D10 A;  4GN1 A;  5JHH A;  2DYQ A;  1W1G A;  2ROZ B;  2X18 A;  2YT2 A;  3KRX A;  3P7Z A;  2Y8G A;  1U29 A;  4DXA B;  2DTC A;  2QKM A;  5C79 A;  3KZ1 A;  4NY0 A;  4A6K A;  3FSS A;  3ODX A;  5HE1 A;  3VIA A;  2MDX A;  2KR0 A;  1U5F A;  2DKQ A;  5C5B A;  5IRS A;  4ZRK A;  5C6R A;  5FI1 A;  5I2M A;  2DX1 A;  2L2I A;  3CXB B;  2Q13 A;  2Z4D A;  3TCA A;  3A98 B;  2J0M A;  2JP2 A;  1V88 A;  2ZPY A;  2Z0Q A;  2N23 A;  2DHK A;  2Z14 A;  1MI1 A;  3TVV A;  1XD4 A;  2ROV A;  1WVH A;  2N0Y A;  5C16 A;  1TXD A;  2LOX A;  1U5D A;  4K2O A;  1XOD A;  1XCG A;  1M7E A;  2ADZ A;  4CYE A;  1K5G B;  2J0J A;  2D9Z A;  1KZ7 A;  4P7I A;  4EJN A;  1ISN A;  2L1C A;  4KHB B;  2MKR A;  2J0K A;  2DX5 A;  1TQZ A;  2COC A;  1GC7 A;  4DIX A;  1X11 A;  2Y8F A;  2EMS A;  1I2H A;  2VKI A;  4WSF A;  1MPH A;  3DCX A;  1BWN A;  4A6F A;  3ZDT A;  4GOU A;  4TKN A;  2MWN B;  2I1K A;  2FJU B;  3IVF A;  4KAX B;  1X1F A;  5DHF B;  1EAZ A;  1BAK A;  2YVC A;  2LUL A;  1KZG A;  2D2Q A;  3PSC A;  4KHA A;  4MY6 A;  2NZ8 B;  2PZ1 A;  2ELA A;  2EMT A;  4K2P A;  1FB8 A;  1WI1 A;  1EVH A;  1MKE A;  1M7R A;  1EF1 A;  5LOP B;  1RJ2 A;  4MT7 A;  2LKO A;  4EMO A;  1ZVR A;  2KIG A;  2RLO A;  3DXD A;  3T06 A;  3U8Z A;  1U27 A;  1UPQ A;  4F7U P;  2P0F A;  1U5G A;  4HAW B;  2NBV A;  1MIX A;  3ML4 A;  3ULB A;  1U5E A;  1Y19 B;  5D3V A;  2W2W A;  3SYX A;  3NWA A;  5DIF B;  1X05 A;  4CHM A;  1BTN A;  1WGQ A;  2CY4 A; 
#chains in the Genus database with same CATH homology
 2K2J A;  4MK0 A;  4GPT B;  3KRW A;  4DX8 A;  1FOE A;  2YS3 A;  2YSZ A;  4HAV B;  4CHJ A;  4L6E A;  2EC1 A;  2GS0 A;  1U2B A;  2FJL A;  4KVG B;  2QKL A;  1QC6 A;  3FM8 C;  2COD A;  3PEG A;  1NU2 A;  4DX9 0;  3QWM A;  2DLW A;  2OTX A;  3LJU X;  4HAZ B;  2CRF A;  3DXC A;  4PNK A;  4EKU A;  1DRO A;  5JLJ B;  3X23 A;  3D8E A;  2M38 A;  1PLS A;  4B6H A;  3UZT A;  2IYB A;  1FHO A;  3PVU A;  1ZC4 B;  4HAX B;  1ZSQ A;  3V5W A;  3SNH A;  5C5B B;  2VSZ A;  3WA0 A;  3CIK A;  1V89 A;  2RSG A;  4A6H A;  2LYD A;  1TJ6 A;  3BIN A;  2UVM A;  4KHO A;  2GJY A;  5D3X A;  1UEF A;  4HB0 B;  4C0A A;  5DH9 B;  3PVL A;  5CLL B;  1E5W A;  2ELB A;  4PQ0 A;  3G9W A;  3PVW A;  2DYN A;  3ZVR A;  2D11 A;  4F7H A;  1MK9 B;  2I5C A;  2K00 A;  2YT0 A;  3SUZ A;  1Z87 A;  5DHA B;  1FHW A;  1AWE A;  2G35 A;  1X86 A;  5D27 A;  5KQ4 A;  2RNR B;  4Z2M B;  4F7G A;  1WJ1 A;  3TFM A;  3QIJ A;  3TO1 A;  4GXB A;  3AJ4 A;  2DHJ A;  4YL8 A;  3DXE A;  2I5F A;  1SHC A;  5KCV A;  4Z2N A;  1MK7 B;  1V5M A;  5HE2 A;  2UZR A;  2LG1 A;  2DKP A;  2HE7 A;  1FGZ A;  1LW3 A;  4H8S A;  2Y7B A;  2D9V A;  4TYZ A;  4HAY B;  1J0W A;  4HB4 B;  5FI0 A;  4D0N B;  1MAI A;  3ULC A;  1EGX A;  1FAO A;  3AU4 A;  3VOQ A;  1DBH A;  1WG7 A;  3A8Q A;  1IRS A;  2J59 M;  4HAT B;  3GYP A;  4NSW A;  1XKE A;  1X1G A;  5J3T A;  5J3Q A;  3A8P A;  2NMB A;  1OMW A;  5GOW B;  3WYF B;  4YON A;  5L81 A;  2DN6 A;  3PG7 A;  3QBV B;  4K81 A;  2YS1 A;  1PMS A;  3P6A A;  1UNP A;  4Y94 A;  1DDM A;  5JP4 A;  1FGY A;  2YS5 A;  1W1D A;  1OQN A;  3KSY A;  4BBK A;  1GC6 A;  2DFK A;  2D4Q A;  3M1I B;  5J3Y A;  3FEH A;  4HHV A;  3SO6 A;  1LB1 A;  4HB2 B;  1BTK A;  4IFS A;  5HE0 A;  1P5T A;  5CLQ B;  2CY5 A;  3BJI A;  2H7D A;  3D8F A;  1MIZ B;  5LON B;  2VRW B;  2OQB A;  2RVB B;  4HDQ A;  1ZC3 B;  1I7A A;  2Z0O A;  4HAU B;  4WJ7 A;  2DHI A;  2R0D A;  1NI2 A;  2W2X C;  1DYN A;  1P6S A;  2XQN M;  2E2X A;  4IOY X;  2COA A;  1DDW A;  1J19 A;  1NTV A;  1XX0 A;  1W1H A;  2GCL A;  2KUP A;  4WVF B;  2HTH B;  2BCJ A;  3KY9 A;  3OAN A;  5HE3 A;  1DDV A;  4DBB A;  1OY2 A;  5D3W A;  3HW2 B;  2Z0P A;  3ODO A;  3PZD A;  2CAY A;  1AQC A;  2I1J A;  2YF0 A;  2P0D A;  5DI9 B;  1UPR A;  3AU5 A;  2AL6 A;  1V61 A;  1K5D B;  4HDO A;  4GMX B;  3O96 A;  1WGU A;  1Q67 A;  1B55 A;  1XR0 B;  3MDB C;  2D9X A;  2YRY A;  2H7E A;  4K17 A;  4ZRJ A;  5EFX A;  1WJM A;  2KGX B;  4GZU A;  2YT1 A;  3F5R A;  2D9W A;  1Y5O A;  2IFS A;  2R09 A;  3GYO A;  2GCJ A;  4IAP A;  1ZM0 A;  2D9Y A;  5D3Y A;  1RRP B;  1SGH A;  4A6F B;  1NTY A;  1V5U A;  3RCP A;  3SV1 A;  3TW1 A;  3D8D A;  3F0W A;  3PP2 A;  2K2U A;  1PFJ A;  1P3R A;  4GMV A;  4ZRI A;  3N7C A;  5JHG A;  2DA0 A;  1V5P A;  3ODW A;  1H10 A;  2RUK B;  1H4R A;  2M14 A;  4A5K A;  1GG3 A;  1QQG A;  2P0H A;  4XWX A;  3U7D A;  1KI1 B;  3NSU A;  2RGN B;  1UNQ A;  2UZS A;  2COF A;  2V76 A;  3MPX A;  2KCJ A;  3HK0 A;  5KQ1 A;  2MFQ A;  2LOZ A;  2EJ8 A;  2W2X D;  2AEH A;  1FHX A;  1N3H A;  4HB3 B;  1UNR A;  2P8V A;  3HQC A;  2D10 A;  4GN1 A;  5JHH A;  2DYQ A;  1W1G A;  2ROZ B;  2X18 A;  3KRX A;  3P7Z A;  2Y8G A;  1U29 A;  4DXA B;  2DTC A;  2QKM A;  5C79 A;  3KZ1 A;  4NY0 A;  4A6K A;  3FSS A;  3ODX A;  5HE1 A;  3VIA A;  2MDX A;  1U5F A;  2DKQ A;  5C5B A;  4ZRK A;  5C6R A;  5FI1 A;  2DX1 A;  2L2I A;  3CXB B;  2Q13 A;  3TCA A;  3A98 B;  2J0M A;  2JP2 A;  1V88 A;  2ZPY A;  2Z0Q A;  2N23 A;  2DHK A;  3TVV A;  1XD4 A;  2ROV A;  1WVH A;  2N0Y A;  5C16 A;  1TXD A;  2LOX A;  1U5D A;  4K2O A;  1XOD A;  1XCG A;  1M7E A;  2ADZ A;  4CYE A;  1K5G B;  2J0J A;  2D9Z A;  1KZ7 A;  4P7I A;  4EJN A;  1ISN A;  2L1C A;  4KHB B;  2MKR A;  2J0K A;  2DX5 A;  1TQZ A;  2COC A;  1GC7 A;  1X11 A;  2Y8F A;  2EMS A;  1I2H A;  2VKI A;  4WSF A;  1MPH A;  1BWN A;  4A6F A;  3ZDT A;  4TKN A;  2MWN B;  2I1K A;  3IVF A;  4KAX B;  1X1F A;  5DHF B;  1EAZ A;  1BAK A;  2YVC A;  2LUL A;  1KZG A;  2D2Q A;  3PSC A;  4KHA A;  4MY6 A;  2NZ8 B;  2PZ1 A;  2ELA A;  2EMT A;  4K2P A;  1FB8 A;  1WI1 A;  1EVH A;  1MKE A;  1M7R A;  1EF1 A;  5LOP B;  1RJ2 A;  4MT7 A;  2LKO A;  4EMO A;  1ZVR A;  2RLO A;  3DXD A;  3T06 A;  3U8Z A;  1U27 A;  1UPQ A;  4F7U P;  2P0F A;  1U5G A;  4HAW B;  1MIX A;  3ML4 A;  3ULB A;  1U5E A;  1Y19 B;  5D3V A;  2W2W A;  3SYX A;  5DIF B;  1X05 A;  4CHM A;  1BTN A;  1WGQ A;  2CY4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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