4Y14A

Structure of protein tyrosine phosphatase 1b complexed with inhibitor (ptp1b:cpt157633)
Total Genus 105
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
105
sequence length
297
structure length
293
Chain Sequence
EMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title PTP1B inhibition suggests a therapeutic strategy for Rett syndrome.
pubmed doi rcsb
molecule tags Hydrolase/inhibitor
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 105
structure length 293
sequence length 297
chains with identical sequence B
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2015-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4y14A00
1OEOX 2FJNA 1G4US 2Q47A 1OEVA 3U96A 4RH5A 3QCIA 4GE5A 1G1FA 1YGUA 1QXKA 4QUMA 2VEUA 4GE2A 5K9VA 5K22A 1YGRA 4B04A 2SHPA 2I6OA 1RPMA 5HDEA 2PBNA 1Q6NA 2CJZA 2QEPA 3QCCA 4GWFA 3D1HA 1FQ1A 5KA1A 1Q6TA 3QCNA 3D9CA 4HJPA 3A5JA 2A3KA 1J4XA 2GP0A 4NNDA 2CNEA 1PH0A 2I5XA 2NT2A 4ZI4A 3H2XA 4JNBA 1ZZWA 1QZ0A 2FH7A 1AAXA 5GTJA 2I6IA 5IBSA 3SR9A 3SMEA 2CM2A 3QKQA 4NWFA 1YTNA 2Q05A 4BJOA 1VHRA 5KA8A 3O3LA 2PSZA 4HRFA 2I3UA 4OHLA 2FJMA 3ZM1A 3S3FA 3M4UA 1EEOA 1PTUA 4R0SA 5BUGA 5KA0A 5K23A 1XM2A 1YFOA 1NO6A 2HC1A 1X24A 3I80A 5KA9A 4GRYA 3GXHA 4QBEA 3V0DA 2F6ZA 2ZN7A 2I6MA 1OHCA 4ZRTA 1KAVA 4D3PA 2P6XA 1JF7A 1T49A 4RH9A 2OC3A 3EZZA 2B4PA 1ECVA 1OEUA 2CM8A 1ZCLA 4HJQA 3S3EA 3V0FA 2F70A 3QCBA 5M43A 1Q6MA 2DXPA 1V3AA 1G7FA 4RI4A 3AWFA 3BM8A 4ERCA 2A8BA 3CM3A 2CNGA 4WU2A 1U26A 3RO1A 2H4KA 4WU3A 5KADA 5KABA 1OHEA 1LARA 3RGOA 1ONZA 1NZ7A 2QBQA 4GFUA 3BRHA 2AZRA 4I8NA 2Y96A 2QDPA 2QDMA 1PA1A 2VEXA 4D3QA 1OESA 4DGPA 1XRIA 2Y2FA 1JLNA 1YTSA 2R0BA 5AWXA 3CWEA 1XXPA 4DGXA 2F6TA 2NV5A 1G7GA 2OUDA 3QCMA 2HB1A 4H34A 3V0GA 1PYNA 5K24A 1D5RA 5EHRA 1Q6PA 4GRZA 1C84A 4YAAA 2QBSA 2CNHA 2I4GA 4AZ1A 1P15A 2GWOA 2I3RA 2QBPA 2I75A 3F99A 4ZN5A 1PTYA 4KYRA 1BZHA 2CM3A 2PT0A 2YDUA 1XXVA 3MOZA 1YTWA 4KI9A 3F81A 1OEMX 4S0GA 5KA7A 2HNPA 1I9SA 2JJDA 3QCFA 2BGEA 2PA5A 2OOQA 2IMGA 2CMAA 2HVLA 1OHDA 3D42A 2CNFA 4Y14A 4GS0A 2WGPA 1YPTA 2RF6A 4WTYA 3ZV2A 2H4VA 2B49A 4WOHA 2CNIA 1PTVA 3EMUA 1PA9A 3F41A 3ZMPA 3S4EA 3EU0A 4D3RA 1C85A 2NTAA 1PXHA 3QCHA 1NWLA 5J8RA 3MOWA 1MKPA 1GFYA 1L8GA 1KAKA 2BV5A 1ONYA 4OHEA 4PYHA 5KACA 1ZCKA 3NMEA 4RHGA 3OLRA 3O4UA 3BLUA 4NX8A 2F71A 1YWFA 1WRMA 2M3VA 2NT7A 1YZ4A 4JMKA 4PVGA 4YR8B 1A5YA 5K9WA 2F6WA 1LYVA 1C87A 2B4OA 2HY3A 1R6HA 3ZM3A 5BX1A 2J16B 2MBCA 4MBBA 4GE6A 1NNYA 1M3GA 3EAXA 4Y2EA 2H04A 2G6ZA 3O4TA 1LQFA 3RZ2A 1PTTA 1WCHA 3OMHA 3ZM0A 2F6YA 4QBWA 1XBOA 2BZLA 3I7ZA 2HNQA 4OHHA 2VEVA 3S3KA 2P4DA 3F9AA 2F6FA 3N0AA 5BZZA 5KA4A 2CMCA 4TVVA 3V0IA 5K25A 1FPZA 3PS5A 2NZ6A 3QCDA 4GFVA 2CFVA 1Q1MA 4Z6BA 2QCJA 3QCEA 1NL9A 1G1HA 2B4UA 3F9BA 1Q6SA 1L8KA 3QKPA 4BPCA 3AWEA 2GJTA 4ICZA 2H02A 2C46A 1Q6JA 2HC2A 3V0JA 3O4SA 4QAPA 2B4SA 2H03A 2HCMA 3V0EA 2BGDA 4JBCA 2I6PA 5BZXA 4H1OA 2HXPA 2I4HA 2VEWA 3BLTA 3S4OA 2AHSA 2ZMMA 2CM7A 2J16A 5LXQB 1I9TA 3D1QA 4QUNA 2OZ5A 2ESBA 3EB1A 3O5XA 1BZJA 2QBRA 2NLKA 4RKKA 1C83A 1C86A 1G4WR 2PI7A 4RDDA 1NWEA 3D44A 1ZC0A 3AWGA 3LJ8A 1U25A 4IKCA 3ZMQA 1U24A 3ZM2A 3B7OA 4NWGA 1GWZA 4NYHA 5KA2A 2I4EA 5EHPA 3RGQA 4J51A 3MMJA 2E0TA 2F6VA 3QCLA 4R0TA 1OETA 4QAHA 1EENA 4JMJA 3QCGA 2F46A 3A5KA 5KAAA 3V0HA 4OHDA 1SUGA 1I57A 1T4JA 2QCTA 3I36A 2H4GA 1T48A 4R30A 3QCKA 1C88A 2PQ5A 2CMBA 5I6VA 3GXGA 2G59A 2I42A 2C7SA 2BIJA 2I1YA 2I6JA 3S3HA 5KA3A 2QDCA 1WAXA 3D1OA 3QCJA 1BZCA 2B3OA 4OHIA 5IBMA 1G1GA 1RXDA 4KYQA 2J17A 1FPRA 2VEYA 1YN9A 5MMZB 2B07A 4RI5A
chains in the Genus database with same CATH superfamily
1OEOX 2FJNA 1G4US 2Q47A 4HV4A 1OEVA 3U96A 4RH5A 2VTEA 4C12A 3QCIA 4GE5A 1G1FA 1YGUA 1QXKA 4QUMA 2VEUA 4GE2A 5K9VA 5K22A 1YGRA 4B04A 2SHPA 2I6OA 1RPMA 2XJAA 4QF5A 5HDEA 2PBNA 1Q6NA 2CJZA 2QEPA 3QCCA 4GWFA 3D1HA 1FQ1A 5KA1A 1Q6TA 3QCNA 3D9CA 2Y66A 4HJPA 3A5JA 2A3KA 1J4XA 2GP0A 1EEHA 4NNDA 2CNEA 1PH0A 2I5XA 2NT2A 4ZI4A 3H2XA 4JNBA 1ZZWA 1QZ0A 2JFGA 2FH7A 1AAXA 5GTJA 2I6IA 5IBSA 3SR9A 3SMEA 2CM2A 3QKQA 4NWFA 3PYZA 1YTNA 2Q05A 4BJOA 1VHRA 5KA8A 3O3LA 2PSZA 4HRFA 2I3UA 4OHLA 2FJMA 3ZM1A 3S3FA 2GCAA 3M4UA 3LK7A 1EEOA 1PTUA 4R0SA 5BUGA 5KA0A 5K23A 1XM2A 1YFOA 1NO6A 2HC1A 1X24A 3I80A 5KA9A 4GRYA 3GXHA 4CVMA 4QBEA 3V0DA 2F6ZA 1J6UA 2ZN7A 2I6MA 1OHCA 4ZRTA 1KAVA 2VTDA 4D3PA 2P6XA 1JF7A 1T49A 4RH9A 2OC3A 3EZZA 2B4PA 2JFFA 1ECVA 1OEUA 2CM8A 1ZCLA 4HJQA 3S3EA 3V0FA 2F70A 2WTZA 3QCBA 5M43A 1Q6MA 2DXPA 1V3AA 1G7FA 1GQYA 4RI4A 3AWFA 3BM8A 4ERCA 3MVNA 2A8BA 3CM3A 2CNGA 1UAGA 4WU2A 1U26A 3RO1A 2H4KA 2UUPA 4WU3A 5KADA 2XPCA 5KABA 1OHEA 3ZL8A 4BUBA 1LARA 3RGOA 1ONZA 1NZ7A 2QBQA 4GFUA 3BRHA 2AZRA 4I8NA 2Y96A 2QDPA 2QDMA 1PA1A 1P3DA 2VEXA 4D3QA 1OESA 4DGPA 1XRIA 2Y2FA 1JLNA 1YTSA 2R0BA 2VORA 5AWXA 2X5OA 3CWEA 1XXPA 4DGXA 2F6TA 2GC5A 2NV5A 3ZM6A 1G7GA 2OUDA 3QCMA 2HB1A 4H34A 3V0GA 1PYNA 5A5EA 2AM1A 5K24A 1D5RA 5EHRA 1Q6PA 4GRZA 1C84A 4YAAA 4ZIYA 2QBSA 2CNHA 2I4GA 2Y68A 4AZ1A 1P15A 2GWOA 2I3RA 2QBPA 2I75A 3F99A 4ZN5A 1PTYA 4KYRA 1BZHA 2CM3A 2PT0A 2YDUA 1XXVA 3MOZA 1YTWA 4KI9A 3F81A 1OEMX 4S0GA 2AM2A 5KA7A 2HNPA 1I9SA 2JJDA 1GG4A 3QCFA 2BGEA 2PA5A 2OOQA 2IMGA 2CMAA 2HVLA 1OHDA 3D42A 2CNFA 4Y14A 4GS0A 2WGPA 1YPTA 2RF6A 4WTYA 3ZV2A 2H4VA 2B49A 4WOHA 4UAGA 2CNIA 1PTVA 3EMUA 2WJPA 1PA9A 3F41A 3ZMPA 3S4EA 3EU0A 4D3RA 1C85A 2NTAA 1PXHA 3QCHA 1NWLA 5J8RA 3MOWA 1E0DA 1MKPA 1GFYA 1L8GA 1KAKA 2BV5A 1ONYA 4OHEA 4PYHA 5KACA 1ZCKA 3NMEA 4RHGA 1E8CA 3OLRA 3O4UA 3BLUA 4NX8A 2F71A 1YWFA 1WRMA 2M3VA 2NT7A 1YZ4A 4JMKA 4PVGA 4YR8B 1A5YA 5K9WA 3QCZA 2F6WA 1LYVA 1C87A 2B4OA 2HY3A 1R6HA 3N2AA 1W78A 3ZM3A 5BX1A 2J16B 2MBCA 4MBBA 4GE6A 1NNYA 1M3GA 3EAXA 4Y2EA 2H04A 2G6ZA 3O4TA 1LQFA 3RZ2A 1PTTA 1WCHA 1FGSA 3OMHA 3ZM0A 2F6YA 4QBWA 2JFHA 1XBOA 2BZLA 4CVKA 2GCBA 3I7ZA 2HNQA 4OHHA 2VEVA 3S3KA 2P4DA 3F9AA 2F6FA 3N0AA 2UUOA 5BZZA 5KA4A 2CMCA 4TVVA 3V0IA 3ZM5A 5K25A 1FPZA 3PS5A 2NZ6A 3QCDA 4GFVA 2CFVA 1Q1MA 4Z6BA 2QCJA 3QCEA 1NL9A 2Y67A 3HN7A 1G1HA 2B4UA 3F9BA 1Q6SA 2GC6A 1L8KA 4BUCA 3QKPA 4BPCA 3AWEA 2GJTA 4ICZA 2H02A 2C46A 1Q6JA 2HC2A 3V0JA 3O4SA 4QAPA 4QDIA 2B4SA 2H03A 2Y1OA 2HCMA 3V0EA 2BGDA 4JBCA 2I6PA 5BZXA 4H1OA 2HXPA 2I4HA 2VEWA 3BLTA 3S4OA 2AHSA 2ZMMA 2CM7A 2J16A 5LXQB 1I9TA 3D1QA 4QUNA 2OZ5A 2ESBA 3EB1A 3O5XA 1BZJA 2QBRA 2NLKA 4RKKA 1C83A 1C86A 1G4WR 1O5ZA 2PI7A 4RDDA 1NWEA 3D44A 1ZC0A 1JBWA 3AWGA 3LJ8A 1U25A 4IKCA 3ZMQA 2VOSA 1U24A 3ZM2A 3B7OA 4NWGA 1GWZA 4NYHA 5KA2A 2I4EA 5EHPA 3RGQA 4J51A 3MMJA 2E0TA 2F6VA 3QCLA 4R0TA 1OETA 4QAHA 1EENA 4JMJA 3QCGA 2F46A 3A5KA 5KAAA 3V0HA 4OHDA 1SUGA 1I57A 1T4JA 2QCTA 3UAGA 3I36A 2H4GA 1T48A 4R30A 3QCKA 1C88A 1GQQA 2PQ5A 2CMBA 5I6VA 3GXGA 2G59A 2I42A 2C7SA 2BIJA 2I1YA 2I6JA 3S3HA 5KA3A 2QDCA 1WAXA 2F00A 3D1OA 3QCJA 1BZCA 2B3OA 4OHIA 5IBMA 4C13A 4CVLA 1W7KA 1G1GA 5A5FA 1RXDA 4KYQA 2J17A 1JBVA 2VEYA 1FPRA 1P31A 2UAGA 1YN9A 5MMZB 3NRSA 2B07A 4RI5A
chains in the Genus database with same CATH topology
1OEOX 2FJNA 1G4US 2Q47A 1OEVA 3U96A 4RH5A 3QCIA 4GE5A 1G1FA 1YGUA 1QXKA 4QUMA 2VEUA 4GE2A 5K9VA 5K22A 1YGRA 4B04A 2SHPA 2I6OA 1RPMA 5HDEA 2PBNA 1Q6NA 2CJZA 2QEPA 3QCCA 4GWFA 3D1HA 1FQ1A 5KA1A 1Q6TA 3QCNA 3D9CA 4HJPA 3A5JA 2A3KA 1J4XA 2GP0A 4NNDA 2CNEA 1PH0A 2I5XA 2NT2A 4ZI4A 3H2XA 4JNBA 1ZZWA 1QZ0A 2FH7A 1AAXA 5GTJA 2I6IA 5IBSA 3SR9A 3SMEA 2CM2A 3QKQA 4NWFA 1YTNA 2Q05A 4BJOA 1VHRA 5KA8A 3O3LA 2PSZA 4HRFA 2I3UA 4OHLA 2FJMA 3ZM1A 3S3FA 3M4UA 1EEOA 1PTUA 4R0SA 5BUGA 5KA0A 5K23A 1XM2A 1YFOA 1NO6A 2HC1A 1X24A 3I80A 5KA9A 4GRYA 3GXHA 4QBEA 3V0DA 2F6ZA 2ZN7A 2I6MA 1OHCA 4ZRTA 1KAVA 4D3PA 2P6XA 1JF7A 1T49A 4RH9A 2OC3A 3EZZA 2B4PA 1ECVA 1OEUA 2CM8A 1ZCLA 4HJQA 3S3EA 3V0FA 2F70A 3QCBA 5M43A 1Q6MA 2DXPA 1V3AA 1G7FA 4RI4A 3AWFA 3BM8A 4ERCA 2A8BA 3CM3A 2CNGA 4WU2A 1U26A 3RO1A 2H4KA 4WU3A 5KADA 5KABA 1OHEA 1LARA 3RGOA 1ONZA 1NZ7A 2QBQA 4GFUA 3BRHA 2AZRA 4I8NA 2Y96A 2QDPA 2QDMA 1PA1A 2VEXA 4D3QA 1OESA 4DGPA 1XRIA 2Y2FA 1JLNA 1YTSA 2R0BA 5AWXA 3CWEA 1XXPA 4DGXA 2F6TA 2NV5A 1G7GA 2OUDA 3QCMA 2HB1A 4H34A 3V0GA 1PYNA 5K24A 1D5RA 5EHRA 1Q6PA 4GRZA 1C84A 4YAAA 2QBSA 2CNHA 2I4GA 4AZ1A 1P15A 2GWOA 2I3RA 2QBPA 2I75A 3F99A 4ZN5A 1PTYA 4KYRA 1BZHA 2CM3A 2PT0A 2YDUA 1XXVA 3MOZA 1YTWA 4KI9A 3F81A 1OEMX 4S0GA 5KA7A 2HNPA 1I9SA 2JJDA 3QCFA 2BGEA 2PA5A 2OOQA 2IMGA 2CMAA 2HVLA 1OHDA 3D42A 2CNFA 4Y14A 4GS0A 2WGPA 1YPTA 2RF6A 4WTYA 3ZV2A 2H4VA 2B49A 4WOHA 2CNIA 1PTVA 3EMUA 1PA9A 3F41A 3ZMPA 3S4EA 3EU0A 4D3RA 1C85A 2NTAA 1PXHA 3QCHA 1NWLA 5J8RA 3MOWA 1MKPA 1GFYA 1L8GA 1KAKA 2BV5A 1ONYA 4OHEA 4PYHA 5KACA 1ZCKA 3NMEA 4RHGA 3OLRA 3O4UA 3BLUA 4NX8A 2F71A 1YWFA 1WRMA 2M3VA 2NT7A 1YZ4A 4JMKA 4PVGA 4YR8B 1A5YA 5K9WA 2F6WA 1LYVA 1C87A 2B4OA 2HY3A 1R6HA 3ZM3A 5BX1A 2J16B 2MBCA 4MBBA 4GE6A 1NNYA 1M3GA 3EAXA 4Y2EA 2H04A 2G6ZA 3O4TA 1LQFA 3RZ2A 1PTTA 1WCHA 3OMHA 3ZM0A 2F6YA 4QBWA 1XBOA 2BZLA 3I7ZA 2HNQA 4OHHA 2VEVA 3S3KA 2P4DA 3F9AA 2F6FA 3N0AA 5BZZA 5KA4A 2CMCA 4TVVA 3V0IA 5K25A 1FPZA 3PS5A 2NZ6A 3QCDA 4GFVA 2CFVA 1Q1MA 4Z6BA 2QCJA 3QCEA 1NL9A 1G1HA 2B4UA 3F9BA 1Q6SA 1L8KA 3QKPA 4BPCA 3AWEA 2GJTA 4ICZA 2H02A 2C46A 1Q6JA 2HC2A 3V0JA 3O4SA 4QAPA 2B4SA 2H03A 2HCMA 3V0EA 2BGDA 4JBCA 2I6PA 5BZXA 4H1OA 2HXPA 2I4HA 2VEWA 3BLTA 3S4OA 2AHSA 2ZMMA 2CM7A 2J16A 5LXQB 1I9TA 3D1QA 4QUNA 2OZ5A 2ESBA 3EB1A 3O5XA 1BZJA 2QBRA 2NLKA 4RKKA 1C83A 1C86A 1G4WR 2PI7A 4RDDA 1NWEA 3D44A 1ZC0A 3AWGA 3LJ8A 1U25A 4IKCA 3ZMQA 1U24A 3ZM2A 3B7OA 4NWGA 1GWZA 4NYHA 5KA2A 2I4EA 5EHPA 3RGQA 4J51A 3MMJA 2E0TA 2F6VA 3QCLA 4R0TA 1OETA 4QAHA 1EENA 4JMJA 3QCGA 2F46A 3A5KA 5KAAA 3V0HA 4OHDA 1SUGA 1I57A 1T4JA 2QCTA 3I36A 2H4GA 1T48A 4R30A 3QCKA 1C88A 2PQ5A 2CMBA 5I6VA 3GXGA 2G59A 2I42A 2C7SA 2BIJA 2I1YA 2I6JA 3S3HA 5KA3A 2QDCA 1WAXA 3D1OA 3QCJA 1BZCA 2B3OA 4OHIA 5IBMA 1G1GA 1RXDA 4KYQA 2J17A 1FPRA 2VEYA 1YN9A 5MMZB 2B07A 4RI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OEO X;  2FJN A;  1G4U S;  2Q47 A;  1OEV A;  3U96 A;  4RH5 A;  3QCI A;  4GE5 A;  1G1F A;  1YGU A;  1QXK A;  4QUM A;  2VEU A;  4GE2 A;  5K9V A;  5K22 A;  1YGR A;  4B04 A;  2SHP A;  2I6O A;  1RPM A;  5HDE A;  2PBN A;  1Q6N A;  2CJZ A;  2QEP A;  3QCC A;  4GWF A;  3D1H A;  1FQ1 A;  5KA1 A;  1Q6T A;  3QCN A;  3D9C A;  4HJP A;  3A5J A;  2A3K A;  1J4X A;  2GP0 A;  4NND A;  2CNE A;  1PH0 A;  2I5X A;  2NT2 A;  4ZI4 A;  3H2X A;  4JNB A;  1ZZW A;  1QZ0 A;  2FH7 A;  1AAX A;  5GTJ A;  2I6I A;  5IBS A;  3SR9 A;  3SME A;  2CM2 A;  3QKQ A;  4NWF A;  1YTN A;  2Q05 A;  4BJO A;  1VHR A;  5KA8 A;  3O3L A;  2PSZ A;  4HRF A;  2I3U A;  4OHL A;  2FJM A;  3ZM1 A;  3S3F A;  3M4U A;  1EEO A;  1PTU A;  4R0S A;  5BUG A;  5KA0 A;  5K23 A;  1XM2 A;  1YFO A;  1NO6 A;  2HC1 A;  1X24 A;  3I80 A;  5KA9 A;  4GRY A;  3GXH A;  4QBE A;  3V0D A;  2F6Z A;  2ZN7 A;  2I6M A;  1OHC A;  4ZRT A;  1KAV A;  4D3P A;  2P6X A;  1JF7 A;  1T49 A;  4RH9 A;  2OC3 A;  3EZZ A;  2B4P A;  1ECV A;  1OEU A;  2CM8 A;  1ZCL A;  4HJQ A;  3S3E A;  3V0F A;  2F70 A;  3QCB A;  5M43 A;  1Q6M A;  2DXP A;  1V3A A;  1G7F A;  4RI4 A;  3AWF A;  3BM8 A;  4ERC A;  2A8B A;  3CM3 A;  2CNG A;  4WU2 A;  1U26 A;  3RO1 A;  2H4K A;  4WU3 A;  5KAD A;  5KAB A;  1OHE A;  1LAR A;  3RGO A;  1ONZ A;  1NZ7 A;  2QBQ A;  4GFU A;  3BRH A;  2AZR A;  4I8N A;  2Y96 A;  2QDP A;  2QDM A;  1PA1 A;  2VEX A;  4D3Q A;  1OES A;  4DGP A;  1XRI A;  2Y2F A;  1JLN A;  1YTS A;  2R0B A;  5AWX A;  3CWE A;  1XXP A;  4DGX A;  2F6T A;  2NV5 A;  1G7G A;  2OUD A;  3QCM A;  2HB1 A;  4H34 A;  3V0G A;  1PYN A;  5K24 A;  1D5R A;  5EHR A;  1Q6P A;  4GRZ A;  1C84 A;  4YAA A;  2QBS A;  2CNH A;  2I4G A;  4AZ1 A;  1P15 A;  2GWO A;  2I3R A;  2QBP A;  2I75 A;  3F99 A;  4ZN5 A;  1PTY A;  4KYR A;  1BZH A;  2CM3 A;  2PT0 A;  2YDU A;  1XXV A;  3MOZ A;  1YTW A;  4KI9 A;  3F81 A;  1OEM X;  4S0G A;  5KA7 A;  2HNP A;  1I9S A;  2JJD A;  3QCF A;  2BGE A;  2PA5 A;  2OOQ A;  2IMG A;  2CMA A;  2HVL A;  1OHD A;  3D42 A;  2CNF A;  4Y14 A;  4GS0 A;  2WGP A;  1YPT A;  2RF6 A;  4WTY A;  3ZV2 A;  2H4V A;  2B49 A;  4WOH A;  2CNI A;  1PTV A;  3EMU A;  1PA9 A;  3F41 A;  3ZMP A;  3S4E A;  3EU0 A;  4D3R A;  1C85 A;  2NTA A;  1PXH A;  3QCH A;  1NWL A;  5J8R A;  3MOW A;  1MKP A;  1GFY A;  1L8G A;  1KAK A;  2BV5 A;  1ONY A;  4OHE A;  4PYH A;  5KAC A;  1ZCK A;  3NME A;  4RHG A;  3OLR A;  3O4U A;  3BLU A;  4NX8 A;  2F71 A;  1YWF A;  1WRM A;  2M3V A;  2NT7 A;  1YZ4 A;  4JMK A;  4PVG A;  4YR8 B;  1A5Y A;  5K9W A;  2F6W A;  1LYV A;  1C87 A;  2B4O A;  2HY3 A;  1R6H A;  3ZM3 A;  5BX1 A;  2J16 B;  2MBC A;  4MBB A;  4GE6 A;  1NNY A;  1M3G A;  3EAX A;  4Y2E A;  2H04 A;  2G6Z A;  3O4T A;  1LQF A;  3RZ2 A;  1PTT A;  1WCH A;  3OMH A;  3ZM0 A;  2F6Y A;  4QBW A;  1XBO A;  2BZL A;  3I7Z A;  2HNQ A;  4OHH A;  2VEV A;  3S3K A;  2P4D A;  3F9A A;  2F6F A;  3N0A A;  5BZZ A;  5KA4 A;  2CMC A;  4TVV A;  3V0I A;  5K25 A;  1FPZ A;  3PS5 A;  2NZ6 A;  3QCD A;  4GFV A;  2CFV A;  1Q1M A;  4Z6B A;  2QCJ A;  3QCE A;  1NL9 A;  1G1H A;  2B4U A;  3F9B A;  1Q6S A;  1L8K A;  3QKP A;  4BPC A;  3AWE A;  2GJT A;  4ICZ A;  2H02 A;  2C46 A;  1Q6J A;  2HC2 A;  3V0J A;  3O4S A;  4QAP A;  2B4S A;  2H03 A;  2HCM A;  3V0E A;  2BGD A;  4JBC A;  2I6P A;  5BZX A;  4H1O A;  2HXP A;  2I4H A;  2VEW A;  3BLT A;  3S4O A;  2AHS A;  2ZMM A;  2CM7 A;  2J16 A;  5LXQ B;  1I9T A;  3D1Q A;  4QUN A;  2OZ5 A;  2ESB A;  3EB1 A;  3O5X A;  1BZJ A;  2QBR A;  2NLK A;  4RKK A;  1C83 A;  1C86 A;  1G4W R;  2PI7 A;  4RDD A;  1NWE A;  3D44 A;  1ZC0 A;  3AWG A;  3LJ8 A;  1U25 A;  4IKC A;  3ZMQ A;  1U24 A;  3ZM2 A;  3B7O A;  4NWG A;  1GWZ A;  4NYH A;  5KA2 A;  2I4E A;  5EHP A;  3RGQ A;  4J51 A;  3MMJ A;  2E0T A;  2F6V A;  3QCL A;  4R0T A;  1OET A;  4QAH A;  1EEN A;  4JMJ A;  3QCG A;  2F46 A;  3A5K A;  5KAA A;  3V0H A;  4OHD A;  1SUG A;  1I57 A;  1T4J A;  2QCT A;  3I36 A;  2H4G A;  1T48 A;  4R30 A;  3QCK A;  1C88 A;  2PQ5 A;  2CMB A;  5I6V A;  3GXG A;  2G59 A;  2I42 A;  2C7S A;  2BIJ A;  2I1Y A;  2I6J A;  3S3H A;  5KA3 A;  2QDC A;  1WAX A;  3D1O A;  3QCJ A;  1BZC A;  2B3O A;  4OHI A;  5IBM A;  1G1G A;  1RXD A;  4KYQ A;  2J17 A;  1FPR A;  2VEY A;  1YN9 A;  5MMZ B;  2B07 A;  4RI5 A; 
#chains in the Genus database with same CATH topology
 1OEO X;  2FJN A;  1G4U S;  2Q47 A;  4HV4 A;  1OEV A;  3U96 A;  4RH5 A;  2VTE A;  4C12 A;  3QCI A;  4GE5 A;  1G1F A;  1YGU A;  1QXK A;  4QUM A;  2VEU A;  4GE2 A;  5K9V A;  5K22 A;  1YGR A;  4B04 A;  2SHP A;  2I6O A;  1RPM A;  2XJA A;  4QF5 A;  5HDE A;  2PBN A;  1Q6N A;  2CJZ A;  2QEP A;  3QCC A;  4GWF A;  3D1H A;  1FQ1 A;  5KA1 A;  1Q6T A;  3QCN A;  3D9C A;  2Y66 A;  4HJP A;  3A5J A;  2A3K A;  1J4X A;  2GP0 A;  1EEH A;  4NND A;  2CNE A;  1PH0 A;  2I5X A;  2NT2 A;  4ZI4 A;  3H2X A;  4JNB A;  1ZZW A;  1QZ0 A;  2JFG A;  2FH7 A;  1AAX A;  5GTJ A;  2I6I A;  5IBS A;  3SR9 A;  3SME A;  2CM2 A;  3QKQ A;  4NWF A;  3PYZ A;  1YTN A;  2Q05 A;  4BJO A;  1VHR A;  5KA8 A;  3O3L A;  2PSZ A;  4HRF A;  2I3U A;  4OHL A;  2FJM A;  3ZM1 A;  3S3F A;  2GCA A;  3M4U A;  3LK7 A;  1EEO A;  1PTU A;  4R0S A;  5BUG A;  5KA0 A;  5K23 A;  1XM2 A;  1YFO A;  1NO6 A;  2HC1 A;  1X24 A;  3I80 A;  5KA9 A;  4GRY A;  3GXH A;  4CVM A;  4QBE A;  3V0D A;  2F6Z A;  1J6U A;  2ZN7 A;  2I6M A;  1OHC A;  4ZRT A;  1KAV A;  2VTD A;  4D3P A;  2P6X A;  1JF7 A;  1T49 A;  4RH9 A;  2OC3 A;  3EZZ A;  2B4P A;  2JFF A;  1ECV A;  1OEU A;  2CM8 A;  1ZCL A;  4HJQ A;  3S3E A;  3V0F A;  2F70 A;  2WTZ A;  3QCB A;  5M43 A;  1Q6M A;  2DXP A;  1V3A A;  1G7F A;  1GQY A;  4RI4 A;  3AWF A;  3BM8 A;  4ERC A;  3MVN A;  2A8B A;  3CM3 A;  2CNG A;  1UAG A;  4WU2 A;  1U26 A;  3RO1 A;  2H4K A;  2UUP A;  4WU3 A;  5KAD A;  2XPC A;  5KAB A;  1OHE A;  3ZL8 A;  4BUB A;  1LAR A;  3RGO A;  1ONZ A;  1NZ7 A;  2QBQ A;  4GFU A;  3BRH A;  2AZR A;  4I8N A;  2Y96 A;  2QDP A;  2QDM A;  1PA1 A;  1P3D A;  2VEX A;  4D3Q A;  1OES A;  4DGP A;  1XRI A;  2Y2F A;  1JLN A;  1YTS A;  2R0B A;  2VOR A;  5AWX A;  2X5O A;  3CWE A;  1XXP A;  4DGX A;  2F6T A;  2GC5 A;  2NV5 A;  3ZM6 A;  1G7G A;  2OUD A;  3QCM A;  2HB1 A;  4H34 A;  3V0G A;  1PYN A;  5A5E A;  2AM1 A;  5K24 A;  1D5R A;  5EHR A;  1Q6P A;  4GRZ A;  1C84 A;  4YAA A;  4ZIY A;  2QBS A;  2CNH A;  2I4G A;  2Y68 A;  4AZ1 A;  1P15 A;  2GWO A;  2I3R A;  2QBP A;  2I75 A;  3F99 A;  4ZN5 A;  1PTY A;  4KYR A;  1BZH A;  2CM3 A;  2PT0 A;  2YDU A;  1XXV A;  3MOZ A;  1YTW A;  4KI9 A;  3F81 A;  1OEM X;  4S0G A;  2AM2 A;  5KA7 A;  2HNP A;  1I9S A;  2JJD A;  1GG4 A;  3QCF A;  2BGE A;  2PA5 A;  2OOQ A;  2IMG A;  2CMA A;  2HVL A;  1OHD A;  3D42 A;  2CNF A;  4Y14 A;  4GS0 A;  2WGP A;  1YPT A;  2RF6 A;  4WTY A;  3ZV2 A;  2H4V A;  2B49 A;  4WOH A;  4UAG A;  2CNI A;  1PTV A;  3EMU A;  2WJP A;  1PA9 A;  3F41 A;  3ZMP A;  3S4E A;  3EU0 A;  4D3R A;  1C85 A;  2NTA A;  1PXH A;  3QCH A;  1NWL A;  5J8R A;  3MOW A;  1E0D A;  1MKP A;  1GFY A;  1L8G A;  1KAK A;  2BV5 A;  1ONY A;  4OHE A;  4PYH A;  5KAC A;  1ZCK A;  3NME A;  4RHG A;  1E8C A;  3OLR A;  3O4U A;  3BLU A;  4NX8 A;  2F71 A;  1YWF A;  1WRM A;  2M3V A;  2NT7 A;  1YZ4 A;  4JMK A;  4PVG A;  4YR8 B;  1A5Y A;  5K9W A;  3QCZ A;  2F6W A;  1LYV A;  1C87 A;  2B4O A;  2HY3 A;  1R6H A;  3N2A A;  1W78 A;  3ZM3 A;  5BX1 A;  2J16 B;  2MBC A;  4MBB A;  4GE6 A;  1NNY A;  1M3G A;  3EAX A;  4Y2E A;  2H04 A;  2G6Z A;  3O4T A;  1LQF A;  3RZ2 A;  1PTT A;  1WCH A;  1FGS A;  3OMH A;  3ZM0 A;  2F6Y A;  4QBW A;  2JFH A;  1XBO A;  2BZL A;  4CVK A;  2GCB A;  3I7Z A;  2HNQ A;  4OHH A;  2VEV A;  3S3K A;  2P4D A;  3F9A A;  2F6F A;  3N0A A;  2UUO A;  5BZZ A;  5KA4 A;  2CMC A;  4TVV A;  3V0I A;  3ZM5 A;  5K25 A;  1FPZ A;  3PS5 A;  2NZ6 A;  3QCD A;  4GFV A;  2CFV A;  1Q1M A;  4Z6B A;  2QCJ A;  3QCE A;  1NL9 A;  2Y67 A;  3HN7 A;  1G1H A;  2B4U A;  3F9B A;  1Q6S A;  2GC6 A;  1L8K A;  4BUC A;  3QKP A;  4BPC A;  3AWE A;  2GJT A;  4ICZ A;  2H02 A;  2C46 A;  1Q6J A;  2HC2 A;  3V0J A;  3O4S A;  4QAP A;  4QDI A;  2B4S A;  2H03 A;  2Y1O A;  2HCM A;  3V0E A;  2BGD A;  4JBC A;  2I6P A;  5BZX A;  4H1O A;  2HXP A;  2I4H A;  2VEW A;  3BLT A;  3S4O A;  2AHS A;  2ZMM A;  2CM7 A;  2J16 A;  5LXQ B;  1I9T A;  3D1Q A;  4QUN A;  2OZ5 A;  2ESB A;  3EB1 A;  3O5X A;  1BZJ A;  2QBR A;  2NLK A;  4RKK A;  1C83 A;  1C86 A;  1G4W R;  1O5Z A;  2PI7 A;  4RDD A;  1NWE A;  3D44 A;  1ZC0 A;  1JBW A;  3AWG A;  3LJ8 A;  1U25 A;  4IKC A;  3ZMQ A;  2VOS A;  1U24 A;  3ZM2 A;  3B7O A;  4NWG A;  1GWZ A;  4NYH A;  5KA2 A;  2I4E A;  5EHP A;  3RGQ A;  4J51 A;  3MMJ A;  2E0T A;  2F6V A;  3QCL A;  4R0T A;  1OET A;  4QAH A;  1EEN A;  4JMJ A;  3QCG A;  2F46 A;  3A5K A;  5KAA A;  3V0H A;  4OHD A;  1SUG A;  1I57 A;  1T4J A;  2QCT A;  3UAG A;  3I36 A;  2H4G A;  1T48 A;  4R30 A;  3QCK A;  1C88 A;  1GQQ A;  2PQ5 A;  2CMB A;  5I6V A;  3GXG A;  2G59 A;  2I42 A;  2C7S A;  2BIJ A;  2I1Y A;  2I6J A;  3S3H A;  5KA3 A;  2QDC A;  1WAX A;  2F00 A;  3D1O A;  3QCJ A;  1BZC A;  2B3O A;  4OHI A;  5IBM A;  4C13 A;  4CVL A;  1W7K A;  1G1G A;  5A5F A;  1RXD A;  4KYQ A;  2J17 A;  1JBV A;  2VEY A;  1FPR A;  1P31 A;  2UAG A;  1YN9 A;  5MMZ B;  3NRS A;  2B07 A;  4RI5 A; 
#chains in the Genus database with same CATH homology
 1OEO X;  2FJN A;  1G4U S;  2Q47 A;  1OEV A;  3U96 A;  4RH5 A;  3QCI A;  4GE5 A;  1G1F A;  1YGU A;  1QXK A;  4QUM A;  2VEU A;  4GE2 A;  5K9V A;  5K22 A;  1YGR A;  4B04 A;  2SHP A;  2I6O A;  1RPM A;  5HDE A;  2PBN A;  1Q6N A;  2CJZ A;  2QEP A;  3QCC A;  4GWF A;  3D1H A;  1FQ1 A;  5KA1 A;  1Q6T A;  3QCN A;  3D9C A;  4HJP A;  3A5J A;  2A3K A;  1J4X A;  2GP0 A;  4NND A;  2CNE A;  1PH0 A;  2I5X A;  2NT2 A;  4ZI4 A;  3H2X A;  4JNB A;  1ZZW A;  1QZ0 A;  2FH7 A;  1AAX A;  5GTJ A;  2I6I A;  5IBS A;  3SR9 A;  3SME A;  2CM2 A;  3QKQ A;  4NWF A;  1YTN A;  2Q05 A;  4BJO A;  1VHR A;  5KA8 A;  3O3L A;  2PSZ A;  4HRF A;  2I3U A;  4OHL A;  2FJM A;  3ZM1 A;  3S3F A;  3M4U A;  1EEO A;  1PTU A;  4R0S A;  5BUG A;  5KA0 A;  5K23 A;  1XM2 A;  1YFO A;  1NO6 A;  2HC1 A;  1X24 A;  3I80 A;  5KA9 A;  4GRY A;  3GXH A;  4QBE A;  3V0D A;  2F6Z A;  2ZN7 A;  2I6M A;  1OHC A;  4ZRT A;  1KAV A;  4D3P A;  2P6X A;  1JF7 A;  1T49 A;  4RH9 A;  2OC3 A;  3EZZ A;  2B4P A;  1ECV A;  1OEU A;  2CM8 A;  1ZCL A;  4HJQ A;  3S3E A;  3V0F A;  2F70 A;  3QCB A;  5M43 A;  1Q6M A;  2DXP A;  1V3A A;  1G7F A;  4RI4 A;  3AWF A;  3BM8 A;  4ERC A;  2A8B A;  3CM3 A;  2CNG A;  4WU2 A;  1U26 A;  3RO1 A;  2H4K A;  4WU3 A;  5KAD A;  5KAB A;  1OHE A;  1LAR A;  3RGO A;  1ONZ A;  1NZ7 A;  2QBQ A;  4GFU A;  3BRH A;  2AZR A;  4I8N A;  2Y96 A;  2QDP A;  2QDM A;  1PA1 A;  2VEX A;  4D3Q A;  1OES A;  4DGP A;  1XRI A;  2Y2F A;  1JLN A;  1YTS A;  2R0B A;  5AWX A;  3CWE A;  1XXP A;  4DGX A;  2F6T A;  2NV5 A;  1G7G A;  2OUD A;  3QCM A;  2HB1 A;  4H34 A;  3V0G A;  1PYN A;  5K24 A;  1D5R A;  5EHR A;  1Q6P A;  4GRZ A;  1C84 A;  4YAA A;  2QBS A;  2CNH A;  2I4G A;  4AZ1 A;  1P15 A;  2GWO A;  2I3R A;  2QBP A;  2I75 A;  3F99 A;  4ZN5 A;  1PTY A;  4KYR A;  1BZH A;  2CM3 A;  2PT0 A;  2YDU A;  1XXV A;  3MOZ A;  1YTW A;  4KI9 A;  3F81 A;  1OEM X;  4S0G A;  5KA7 A;  2HNP A;  1I9S A;  2JJD A;  3QCF A;  2BGE A;  2PA5 A;  2OOQ A;  2IMG A;  2CMA A;  2HVL A;  1OHD A;  3D42 A;  2CNF A;  4Y14 A;  4GS0 A;  2WGP A;  1YPT A;  2RF6 A;  4WTY A;  3ZV2 A;  2H4V A;  2B49 A;  4WOH A;  2CNI A;  1PTV A;  3EMU A;  1PA9 A;  3F41 A;  3ZMP A;  3S4E A;  3EU0 A;  4D3R A;  1C85 A;  2NTA A;  1PXH A;  3QCH A;  1NWL A;  5J8R A;  3MOW A;  1MKP A;  1GFY A;  1L8G A;  1KAK A;  2BV5 A;  1ONY A;  4OHE A;  4PYH A;  5KAC A;  1ZCK A;  3NME A;  4RHG A;  3OLR A;  3O4U A;  3BLU A;  4NX8 A;  2F71 A;  1YWF A;  1WRM A;  2M3V A;  2NT7 A;  1YZ4 A;  4JMK A;  4PVG A;  4YR8 B;  1A5Y A;  5K9W A;  2F6W A;  1LYV A;  1C87 A;  2B4O A;  2HY3 A;  1R6H A;  3ZM3 A;  5BX1 A;  2J16 B;  2MBC A;  4MBB A;  4GE6 A;  1NNY A;  1M3G A;  3EAX A;  4Y2E A;  2H04 A;  2G6Z A;  3O4T A;  1LQF A;  3RZ2 A;  1PTT A;  1WCH A;  3OMH A;  3ZM0 A;  2F6Y A;  4QBW A;  1XBO A;  2BZL A;  3I7Z A;  2HNQ A;  4OHH A;  2VEV A;  3S3K A;  2P4D A;  3F9A A;  2F6F A;  3N0A A;  5BZZ A;  5KA4 A;  2CMC A;  4TVV A;  3V0I A;  5K25 A;  1FPZ A;  3PS5 A;  2NZ6 A;  3QCD A;  4GFV A;  2CFV A;  1Q1M A;  4Z6B A;  2QCJ A;  3QCE A;  1NL9 A;  1G1H A;  2B4U A;  3F9B A;  1Q6S A;  1L8K A;  3QKP A;  4BPC A;  3AWE A;  2GJT A;  4ICZ A;  2H02 A;  2C46 A;  1Q6J A;  2HC2 A;  3V0J A;  3O4S A;  4QAP A;  2B4S A;  2H03 A;  2HCM A;  3V0E A;  2BGD A;  4JBC A;  2I6P A;  5BZX A;  4H1O A;  2HXP A;  2I4H A;  2VEW A;  3BLT A;  3S4O A;  2AHS A;  2ZMM A;  2CM7 A;  2J16 A;  5LXQ B;  1I9T A;  3D1Q A;  4QUN A;  2OZ5 A;  2ESB A;  3EB1 A;  3O5X A;  1BZJ A;  2QBR A;  2NLK A;  4RKK A;  1C83 A;  1C86 A;  1G4W R;  2PI7 A;  4RDD A;  1NWE A;  3D44 A;  1ZC0 A;  3AWG A;  3LJ8 A;  1U25 A;  4IKC A;  3ZMQ A;  1U24 A;  3ZM2 A;  3B7O A;  4NWG A;  1GWZ A;  4NYH A;  5KA2 A;  2I4E A;  5EHP A;  3RGQ A;  4J51 A;  3MMJ A;  2E0T A;  2F6V A;  3QCL A;  4R0T A;  1OET A;  4QAH A;  1EEN A;  4JMJ A;  3QCG A;  2F46 A;  3A5K A;  5KAA A;  3V0H A;  4OHD A;  1SUG A;  1I57 A;  1T4J A;  2QCT A;  3I36 A;  2H4G A;  1T48 A;  4R30 A;  3QCK A;  1C88 A;  2PQ5 A;  2CMB A;  5I6V A;  3GXG A;  2G59 A;  2I42 A;  2C7S A;  2BIJ A;  2I1Y A;  2I6J A;  3S3H A;  5KA3 A;  2QDC A;  1WAX A;  3D1O A;  3QCJ A;  1BZC A;  2B3O A;  4OHI A;  5IBM A;  1G1G A;  1RXD A;  4KYQ A;  2J17 A;  1FPR A;  2VEY A;  1YN9 A;  5MMZ B;  2B07 A;  4RI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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