4ZG7A

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 247
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
247
Knots found
sequence length
806
structure length
776
Chain Sequence
b'ISGSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIAALTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDCFFQGDHGFDNKVNSMQTVFVGYGPTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase/hydrolase inhibitor
total genus 247
structure length 776
sequence length 806
other databases KnotProt 2.0: S +31
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zg7A04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zg7A03
5L0BA 3B5QA 2IUCB 2GSNA 4QH0A 1P49A 5GOVA 4UPLA 1K7HA 2GLQA 3BDGA 3ED4A 1ELXA 4NWJA 1E1ZP 1KHLA 1N2KA 2W8DA 3WBHA 3KD8A 4ZG9A 1ELZA 4ZGAA 2W5VA 2W5SA 4TN0A 5LIAA 1AJAA 2XGRA 2IUCA 3E2DA 3DYCA 3LXQA 4LQYA 5AJ9A 4QAXA 5TJ3A 3NKMA 3SZZA 4E3YA 5EGEA 4NWXA 3CMRA 1EW9A 3NKOA 1E33P 4QGOA 1KH5A 1URBA 3UNYA 3BDHA 3MK1A 3NVLA 1KHKA 1SHQA 3UO0A 1KHJA 3OWVA 3DPCA 1QAEA 2QZUA 4A1NA 3M8YA 3S5BA 2W8SA 4LRDA 5KXAA 3NKNA 1Y6VA 5K4PA 5GRRA 1URAA 1QL0A 4UOPA 1ALHA 1ED9A 5L0EA 3IGZB 4LRAA 4QN0A 4YR1A 3NKPA 3T02A 4CXSA 1ALKA 1ZEFA 1E2SP 4KM4A 4KJDA 3OT9A 4FDIA 4MHXA 4LR2A 4FDJA 2D1GA 5LRMA 2O3BA 4LRFA 4UPKA 3A52A 1EQJA 2VQRA 4B56A 5LQQA 3T01A 4KAVA 1E3CP 5C66A 2GA3A 3NKQA 3M8ZA 1EI6A 3MK2A 4ZG6A 4GTWA 2XRGA 2RH6A 2GSOA 1ZM8A 1HDHA 3Q3QA 5HRTA 4CXUA 3UN5A 1ALIA 2ZKTA 3TX0A 5LRNA 1ED8A 1B8JA 3WAVA 1KHNA 3WAYA 2ANHA 3WAXA 1N2LA 3NKRA 3ISMA 4GTYA 1HQAA 3IDDA 3SZYA 2W5TA 2W5XA 4KAYA 5DLTA 5IJQA 1AJDA 1ELYA 4KJGA 4MY4A 3MK0A 1ALJA 3WAWA 1ZEDA 2XH3A 2XR9A 4N7TA 2W5WA 4LR8A 1G8TA 5DLWA 1FSUA 4CYSA 1KH7A 5IJSA 3M7VA 4LR9A 3BDFA 4UPIA 1AUKA 1O98A 4LRCA 1HJKA 1KH9A 4MIVA 3UN3A 2GSUA 2W5RA 1AJBA 2W5QA 4ZG7A 3IGYB 1SHNA 5GKCA 4CYRA 4LRBA 1Y7AA 1ANIA 5INHA 4GTXA 1EJJA 3M8WA 1O99A 5L0KA 3T00A 3TWZA 4UPHA 5EGHA 1ZEBA 1SMNA 1ANJA 4UOOA 1AJCA 2G9YA 4CXKA 4LR7A 1EW8A 5GKPA 1EW2A 2IFYA 2X98A 5DLVA 3BDGB 3UN2A 4UORA 3TG0A 4LREA 4GTZA 1KH4A
chains in the Genus database with same CATH superfamily
5L0BA 3B5QA 2IUCB 2GSNA 4QH0A 1P49A 5GOVA 4UPLA 1K7HA 2GLQA 3BDGA 3ED4A 1ELXA 4NWJA 1E1ZP 1KHLA 1N2KA 2W8DA 3WBHA 3KD8A 4ZG9A 1ELZA 4ZGAA 2W5VA 2W5SA 4TN0A 5LIAA 1AJAA 2XGRA 2IUCA 3E2DA 3DYCA 3LXQA 4LQYA 5AJ9A 4QAXA 5TJ3A 3NKMA 3SZZA 4E3YA 5EGEA 4NWXA 3CMRA 1EW9A 3NKOA 1E33P 4QGOA 1KH5A 1URBA 3UNYA 3BDHA 3MK1A 3NVLA 1KHKA 1SHQA 3UO0A 1KHJA 3OWVA 3DPCA 1QAEA 2QZUA 4A1NA 3M8YA 3S5BA 2W8SA 4LRDA 5KXAA 3NKNA 1Y6VA 5K4PA 5GRRA 1URAA 1QL0A 4UOPA 1ALHA 1ED9A 5L0EA 3IGZB 4LRAA 4QN0A 4YR1A 3NKPA 3T02A 4CXSA 1ALKA 1ZEFA 1E2SP 4KM4A 4KJDA 3OT9A 4FDIA 4MHXA 4LR2A 4FDJA 2D1GA 5LRMA 2O3BA 4LRFA 4UPKA 3A52A 1EQJA 2VQRA 4B56A 5LQQA 3T01A 4KAVA 1E3CP 5C66A 2GA3A 3NKQA 3M8ZA 1EI6A 3MK2A 4ZG6A 4GTWA 2XRGA 2RH6A 2GSOA 1ZM8A 1HDHA 3Q3QA 5HRTA 4CXUA 3UN5A 1ALIA 2ZKTA 3TX0A 5LRNA 1ED8A 1B8JA 3WAVA 1KHNA 3WAYA 2ANHA 3WAXA 1N2LA 3NKRA 3ISMA 4GTYA 1HQAA 3IDDA 3SZYA 2W5TA 2W5XA 4KAYA 5DLTA 5IJQA 1AJDA 1ELYA 4KJGA 4MY4A 3MK0A 1ALJA 3WAWA 1ZEDA 2XH3A 2XR9A 4N7TA 2W5WA 4LR8A 1G8TA 5DLWA 1FSUA 4CYSA 1KH7A 5IJSA 3M7VA 4LR9A 3BDFA 4UPIA 1AUKA 1O98A 4LRCA 1HJKA 1KH9A 4MIVA 3UN3A 2GSUA 2W5RA 1AJBA 2W5QA 4ZG7A 3IGYB 1SHNA 5GKCA 4CYRA 4LRBA 1Y7AA 1ANIA 5INHA 4GTXA 1EJJA 3M8WA 1O99A 5L0KA 3T00A 3TWZA 4UPHA 5EGHA 1ZEBA 1SMNA 1ANJA 4UOOA 1AJCA 2G9YA 4CXKA 4LR7A 1EW8A 5GKPA 1EW2A 2IFYA 2X98A 5DLVA 3BDGB 3UN2A 4UORA 3TG0A 4LREA 4GTZA 1KH4A
chains in the Genus database with same CATH topology
5L0BA 3B5QA 2IUCB 2GSNA 4QH0A 1P49A 5GOVA 4UPLA 1K7HA 2GLQA 3BDGA 3ED4A 1ELXA 4NWJA 1E1ZP 1KHLA 1N2KA 2W8DA 3WBHA 3KD8A 4ZG9A 1ELZA 4ZGAA 2W5VA 2W5SA 4TN0A 5LIAA 1AJAA 2XGRA 2IUCA 3E2DA 3DYCA 3LXQA 4LQYA 5AJ9A 4QAXA 5TJ3A 3NKMA 3SZZA 4E3YA 5EGEA 4NWXA 3CMRA 1EW9A 3NKOA 1E33P 4QGOA 1KH5A 1URBA 3UNYA 3BDHA 3MK1A 3NVLA 1KHKA 1SHQA 3UO0A 1KHJA 3OWVA 3DPCA 1QAEA 2QZUA 4A1NA 3M8YA 3S5BA 2W8SA 4LRDA 5KXAA 3NKNA 1Y6VA 5K4PA 5GRRA 1URAA 1QL0A 4UOPA 1ALHA 1ED9A 5L0EA 3IGZB 4LRAA 4QN0A 4YR1A 3NKPA 3T02A 4CXSA 1ALKA 1ZEFA 1E2SP 4KM4A 4KJDA 3OT9A 4FDIA 4MHXA 4LR2A 4FDJA 2D1GA 5LRMA 2O3BA 4LRFA 4UPKA 3A52A 1EQJA 2VQRA 4B56A 5LQQA 3T01A 4KAVA 1E3CP 5C66A 2GA3A 3NKQA 3M8ZA 1EI6A 3MK2A 4ZG6A 4GTWA 2XRGA 2RH6A 2GSOA 1ZM8A 1HDHA 3Q3QA 5HRTA 4CXUA 3UN5A 1ALIA 2ZKTA 3TX0A 5LRNA 1ED8A 1B8JA 3WAVA 1KHNA 3WAYA 2ANHA 3WAXA 1N2LA 3NKRA 3ISMA 4GTYA 1HQAA 3IDDA 3SZYA 2W5TA 2W5XA 4KAYA 5DLTA 5IJQA 1AJDA 1ELYA 4KJGA 4MY4A 3MK0A 1ALJA 3WAWA 1ZEDA 2XH3A 2XR9A 4N7TA 2W5WA 4LR8A 1G8TA 5DLWA 1FSUA 4CYSA 1KH7A 5IJSA 3M7VA 4LR9A 3BDFA 4UPIA 1AUKA 1O98A 4LRCA 1HJKA 1KH9A 4MIVA 3UN3A 2GSUA 2W5RA 1AJBA 2W5QA 4ZG7A 3IGYB 1SHNA 5GKCA 4CYRA 4LRBA 1Y7AA 1ANIA 5INHA 4GTXA 1EJJA 3M8WA 1O99A 5L0KA 3T00A 3TWZA 4UPHA 5EGHA 1ZEBA 1SMNA 1ANJA 4UOOA 1AJCA 2G9YA 4CXKA 4LR7A 1EW8A 5GKPA 1EW2A 2IFYA 2X98A 5DLVA 3BDGB 3UN2A 4UORA 3TG0A 4LREA 4GTZA 1KH4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L0B A;  3B5Q A;  2IUC B;  2GSN A;  4QH0 A;  1P49 A;  5GOV A;  4UPL A;  1K7H A;  2GLQ A;  3BDG A;  3ED4 A;  1ELX A;  4NWJ A;  1E1Z P;  1KHL A;  1N2K A;  2W8D A;  3WBH A;  3KD8 A;  4ZG9 A;  1ELZ A;  4ZGA A;  2W5V A;  2W5S A;  4TN0 A;  5LIA A;  1AJA A;  2XGR A;  2IUC A;  3E2D A;  3DYC A;  3LXQ A;  4LQY A;  5AJ9 A;  4QAX A;  5TJ3 A;  3NKM A;  3SZZ A;  4E3Y A;  5EGE A;  4NWX A;  3CMR A;  1EW9 A;  3NKO A;  1E33 P;  4QGO A;  1KH5 A;  1URB A;  3UNY A;  3BDH A;  3MK1 A;  3NVL A;  1KHK A;  1SHQ A;  3UO0 A;  1KHJ A;  3OWV A;  3DPC A;  1QAE A;  2QZU A;  4A1N A;  3M8Y A;  3S5B A;  2W8S A;  4LRD A;  5KXA A;  3NKN A;  1Y6V A;  5K4P A;  5GRR A;  1URA A;  1QL0 A;  4UOP A;  1ALH A;  1ED9 A;  5L0E A;  3IGZ B;  4LRA A;  4QN0 A;  4YR1 A;  3NKP A;  3T02 A;  4CXS A;  1ALK A;  1ZEF A;  1E2S P;  4KM4 A;  4KJD A;  3OT9 A;  4FDI A;  4MHX A;  4LR2 A;  4FDJ A;  2D1G A;  5LRM A;  2O3B A;  4LRF A;  4UPK A;  3A52 A;  1EQJ A;  2VQR A;  4B56 A;  5LQQ A;  3T01 A;  4KAV A;  1E3C P;  5C66 A;  2GA3 A;  3NKQ A;  3M8Z A;  1EI6 A;  3MK2 A;  4ZG6 A;  4GTW A;  2XRG A;  2RH6 A;  2GSO A;  1ZM8 A;  1HDH A;  3Q3Q A;  5HRT A;  4CXU A;  3UN5 A;  1ALI A;  2ZKT A;  3TX0 A;  5LRN A;  1ED8 A;  1B8J A;  3WAV A;  1KHN A;  3WAY A;  2ANH A;  3WAX A;  1N2L A;  3NKR A;  3ISM A;  4GTY A;  1HQA A;  3IDD A;  3SZY A;  2W5T A;  2W5X A;  4KAY A;  5DLT A;  5IJQ A;  1AJD A;  1ELY A;  4KJG A;  4MY4 A;  3MK0 A;  1ALJ A;  3WAW A;  1ZED A;  2XH3 A;  2XR9 A;  4N7T A;  2W5W A;  4LR8 A;  1G8T A;  5DLW A;  1FSU A;  4CYS A;  1KH7 A;  5IJS A;  3M7V A;  4LR9 A;  3BDF A;  4UPI A;  1AUK A;  1O98 A;  4LRC A;  1HJK A;  1KH9 A;  4MIV A;  3UN3 A;  2GSU A;  2W5R A;  1AJB A;  2W5Q A;  4ZG7 A;  3IGY B;  1SHN A;  5GKC A;  4CYR A;  4LRB A;  1Y7A A;  1ANI A;  5INH A;  4GTX A;  1EJJ A;  3M8W A;  1O99 A;  5L0K A;  3T00 A;  3TWZ A;  4UPH A;  5EGH A;  1ZEB A;  1SMN A;  1ANJ A;  4UOO A;  1AJC A;  2G9Y A;  4CXK A;  4LR7 A;  1EW8 A;  5GKP A;  1EW2 A;  2IFY A;  2X98 A;  5DLV A;  3BDG B;  3UN2 A;  4UOR A;  3TG0 A;  4LRE A;  4GTZ A;  1KH4 A; 
#chains in the Genus database with same CATH topology
 5L0B A;  3B5Q A;  2IUC B;  2GSN A;  4QH0 A;  1P49 A;  5GOV A;  4UPL A;  1K7H A;  2GLQ A;  3BDG A;  3ED4 A;  1ELX A;  4NWJ A;  1E1Z P;  1KHL A;  1N2K A;  2W8D A;  3WBH A;  3KD8 A;  4ZG9 A;  1ELZ A;  4ZGA A;  2W5V A;  2W5S A;  4TN0 A;  5LIA A;  1AJA A;  2XGR A;  2IUC A;  3E2D A;  3DYC A;  3LXQ A;  4LQY A;  5AJ9 A;  4QAX A;  5TJ3 A;  3NKM A;  3SZZ A;  4E3Y A;  5EGE A;  4NWX A;  3CMR A;  1EW9 A;  3NKO A;  1E33 P;  4QGO A;  1KH5 A;  1URB A;  3UNY A;  3BDH A;  3MK1 A;  3NVL A;  1KHK A;  1SHQ A;  3UO0 A;  1KHJ A;  3OWV A;  3DPC A;  1QAE A;  2QZU A;  4A1N A;  3M8Y A;  3S5B A;  2W8S A;  4LRD A;  5KXA A;  3NKN A;  1Y6V A;  5K4P A;  5GRR A;  1URA A;  1QL0 A;  4UOP A;  1ALH A;  1ED9 A;  5L0E A;  3IGZ B;  4LRA A;  4QN0 A;  4YR1 A;  3NKP A;  3T02 A;  4CXS A;  1ALK A;  1ZEF A;  1E2S P;  4KM4 A;  4KJD A;  3OT9 A;  4FDI A;  4MHX A;  4LR2 A;  4FDJ A;  2D1G A;  5LRM A;  2O3B A;  4LRF A;  4UPK A;  3A52 A;  1EQJ A;  2VQR A;  4B56 A;  5LQQ A;  3T01 A;  4KAV A;  1E3C P;  5C66 A;  2GA3 A;  3NKQ A;  3M8Z A;  1EI6 A;  3MK2 A;  4ZG6 A;  4GTW A;  2XRG A;  2RH6 A;  2GSO A;  1ZM8 A;  1HDH A;  3Q3Q A;  5HRT A;  4CXU A;  3UN5 A;  1ALI A;  2ZKT A;  3TX0 A;  5LRN A;  1ED8 A;  1B8J A;  3WAV A;  1KHN A;  3WAY A;  2ANH A;  3WAX A;  1N2L A;  3NKR A;  3ISM A;  4GTY A;  1HQA A;  3IDD A;  3SZY A;  2W5T A;  2W5X A;  4KAY A;  5DLT A;  5IJQ A;  1AJD A;  1ELY A;  4KJG A;  4MY4 A;  3MK0 A;  1ALJ A;  3WAW A;  1ZED A;  2XH3 A;  2XR9 A;  4N7T A;  2W5W A;  4LR8 A;  1G8T A;  5DLW A;  1FSU A;  4CYS A;  1KH7 A;  5IJS A;  3M7V A;  4LR9 A;  3BDF A;  4UPI A;  1AUK A;  1O98 A;  4LRC A;  1HJK A;  1KH9 A;  4MIV A;  3UN3 A;  2GSU A;  2W5R A;  1AJB A;  2W5Q A;  4ZG7 A;  3IGY B;  1SHN A;  5GKC A;  4CYR A;  4LRB A;  1Y7A A;  1ANI A;  5INH A;  4GTX A;  1EJJ A;  3M8W A;  1O99 A;  5L0K A;  3T00 A;  3TWZ A;  4UPH A;  5EGH A;  1ZEB A;  1SMN A;  1ANJ A;  4UOO A;  1AJC A;  2G9Y A;  4CXK A;  4LR7 A;  1EW8 A;  5GKP A;  1EW2 A;  2IFY A;  2X98 A;  5DLV A;  3BDG B;  3UN2 A;  4UOR A;  3TG0 A;  4LRE A;  4GTZ A;  1KH4 A; 
#chains in the Genus database with same CATH homology
 5L0B A;  3B5Q A;  2IUC B;  2GSN A;  4QH0 A;  1P49 A;  5GOV A;  4UPL A;  1K7H A;  2GLQ A;  3BDG A;  3ED4 A;  1ELX A;  4NWJ A;  1E1Z P;  1KHL A;  1N2K A;  2W8D A;  3WBH A;  3KD8 A;  4ZG9 A;  1ELZ A;  4ZGA A;  2W5V A;  2W5S A;  4TN0 A;  5LIA A;  1AJA A;  2XGR A;  2IUC A;  3E2D A;  3DYC A;  3LXQ A;  4LQY A;  5AJ9 A;  4QAX A;  5TJ3 A;  3NKM A;  3SZZ A;  4E3Y A;  5EGE A;  4NWX A;  3CMR A;  1EW9 A;  3NKO A;  1E33 P;  4QGO A;  1KH5 A;  1URB A;  3UNY A;  3BDH A;  3MK1 A;  3NVL A;  1KHK A;  1SHQ A;  3UO0 A;  1KHJ A;  3OWV A;  3DPC A;  1QAE A;  2QZU A;  4A1N A;  3M8Y A;  3S5B A;  2W8S A;  4LRD A;  5KXA A;  3NKN A;  1Y6V A;  5K4P A;  5GRR A;  1URA A;  1QL0 A;  4UOP A;  1ALH A;  1ED9 A;  5L0E A;  3IGZ B;  4LRA A;  4QN0 A;  4YR1 A;  3NKP A;  3T02 A;  4CXS A;  1ALK A;  1ZEF A;  1E2S P;  4KM4 A;  4KJD A;  3OT9 A;  4FDI A;  4MHX A;  4LR2 A;  4FDJ A;  2D1G A;  5LRM A;  2O3B A;  4LRF A;  4UPK A;  3A52 A;  1EQJ A;  2VQR A;  4B56 A;  5LQQ A;  3T01 A;  4KAV A;  1E3C P;  5C66 A;  2GA3 A;  3NKQ A;  3M8Z A;  1EI6 A;  3MK2 A;  4ZG6 A;  4GTW A;  2XRG A;  2RH6 A;  2GSO A;  1ZM8 A;  1HDH A;  3Q3Q A;  5HRT A;  4CXU A;  3UN5 A;  1ALI A;  2ZKT A;  3TX0 A;  5LRN A;  1ED8 A;  1B8J A;  3WAV A;  1KHN A;  3WAY A;  2ANH A;  3WAX A;  1N2L A;  3NKR A;  3ISM A;  4GTY A;  1HQA A;  3IDD A;  3SZY A;  2W5T A;  2W5X A;  4KAY A;  5DLT A;  5IJQ A;  1AJD A;  1ELY A;  4KJG A;  4MY4 A;  3MK0 A;  1ALJ A;  3WAW A;  1ZED A;  2XH3 A;  2XR9 A;  4N7T A;  2W5W A;  4LR8 A;  1G8T A;  5DLW A;  1FSU A;  4CYS A;  1KH7 A;  5IJS A;  3M7V A;  4LR9 A;  3BDF A;  4UPI A;  1AUK A;  1O98 A;  4LRC A;  1HJK A;  1KH9 A;  4MIV A;  3UN3 A;  2GSU A;  2W5R A;  1AJB A;  2W5Q A;  4ZG7 A;  3IGY B;  1SHN A;  5GKC A;  4CYR A;  4LRB A;  1Y7A A;  1ANI A;  5INH A;  4GTX A;  1EJJ A;  3M8W A;  1O99 A;  5L0K A;  3T00 A;  3TWZ A;  4UPH A;  5EGH A;  1ZEB A;  1SMN A;  1ANJ A;  4UOO A;  1AJC A;  2G9Y A;  4CXK A;  4LR7 A;  1EW8 A;  5GKP A;  1EW2 A;  2IFY A;  2X98 A;  5DLV A;  3BDG B;  3UN2 A;  4UOR A;  3TG0 A;  4LRE A;  4GTZ A;  1KH4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...