5ACXA

Vim-2-2, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
233
structure length
231
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords BETA-LACTAMASE
publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
total genus 77
structure length 231
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acxA00
4NQ5A 1WUPA 4ZO3A 5EVKA 4D1TA 3IE2A 4AX0B 5A0TA 4ZEJA 2P97A 5AHRA 3SFPA 4TZBA 5ACSA 4DILA 4V0HA 5AXRA 3FAIA 3QH8A 4C1DA 1BVTA 4GCWA 4FR7A 4PVTA 4AWYB 1X8GA 2WYMA 4UWOB 1DXKA 1VJNA 2ZO4A 4GYQA 4GYUA 1YCFA 2DKFA 3PG4A 2NZEA 4XWWA 5FQCA 1E5DA 1XTOA 3RKJA 1QH3A 2FU7A 2I7XA 3X2ZA 5ACTA 3TP9A 2BGAA 2BG8B 2A7MA 3SD9A 5ACXA 4Z7RA 4RAMA 3BV6A 2P4ZA 2I7VA 4U4LA 1VMEA 2QDSA 3JXPA 1X8IA 5ACWA 4LE6A 3T3OA 1DD6A 4J5FA 5LMCA 2Y87A 3ZNBA 3SPUA 3DHCA 2GFKA 1KO2A 5A0VA 2Q9UA 4HL2A 2HB9A 2BG7A 4C09A 3WXCA 3A4YA 3BK1A 2GCUA 1XM8A 1WUOA 5HISA 2M5DA 2YNVB 1Y44A 4AX1B 5K4NA 4C1GA 3H3EA 4UA4A 3SBLA 2QDTA 4DIKA 4RL0A 2BC2A 1MQOA 4UWPB 2BTNA 4BP0A 5ACPA 3ZR9A 2OHJA 2FHXB 4D1WA 4TZFA 5KIKA 5EW0A 4F6ZA 1A8TA 2NZFA 5HIQA 3AF5A 5LLDA 4RM5A 4FEKA 3F9OA 3G1PA 4D02A 3VPEA 1A7TA 2YNVA 2BFLA 4B87A 2AIOA 2Q0JA 2BFKA 4YSBA 3DHAA 4RL2A 4XWTA 4WD6A 5HIPA 5LCFA 2FHXA 4NQ4A 3X2YA 3X2XA 1ZTCA 3BK2A 4BZ3A 2YNTA 2H6AA 4C1HA 3IE1A 2XF4A 2YNWA 2WYLA 3ZQ4A 4Z6XA 5EH9A 5HH4A 2BFZA 4C1CA 3Q6VA 4EFZA 2R2DA 3L6NA 2WHGA 2GFJA 5ACVA 2ZNBA 4J5HA 3AF6A 5K4KA 5B3RA 4NQ6A 4UWSB 5KILA 5LSCA 5LM6A 1BC2A 3KNSA 1VGNA 2AZ4A 1M2XA 4PVOA 1SMLA 2YNUA 4RBSA 1KO3A 3IOFA 4RAWA 3SW3A 3KNRA 4Z5ZA 3T9MA 4HL1A 2QJSA 3RKKA 2FM6A 2NXAA 3DHBA 4Z67A 1KR3A 4HKYA 2BG6A 5ACQA 2CBNA 4ZNBA 4H0DA 5ACUA 4P62A 4NQ2A 4YSLA 2E7YA 5A5ZA 4JO0A 4EXSA 3I15A 3MD7A 5EV6A 3IDZA 2Y8AA 3ESHA 2FU6A 5K4MA 5FQAA 2YCBA 1ZNBA 2UYXA 3S0ZA 1JJEA 5EVDA 4AD9A 5FQBA 2VW8A 1WRAA 2P18A 4XUKA 2OHHA 5HH6A 4TYTA 4CHLA 2YNTB 2WRSA 4O98A 2WYMC 5EWAA 4EXYA 2GKLA 4D1UA 5IQKA 4FSBA 5HIOA 4Z5YA 2BR6A 3LVZA 3KL7A 2BFZB 5HH5A 1ZKPA 1WW1A 3X30A 2DOOA 2ZWRA 5AHOA 5EHTA 1YCHA 2P1EA 4EYLA 1JT1A 3I0VA 4TZ9A 2GMNA 4TZEA 1L9YA 1BMCA 3T3NA 2FK6A 3PY6A 4Z60A 2YZ3A 5A87A 5AXOA 3IELA 4C1FA 3VQZA 2BMIA 3IE0A 4YSKA 4UWRB 2BIBA 3IEMA 2FU9A 1QH5A 3SRXA 2M5CA 5LCHA 2NYPA 1YCGA 2OHIA 5LE1A 2QINA 2ZZIA 2I7TA 4UAMA 2BG2A 3I11A 2QEDA 4EYFA 5AYAA 4KEPA 2XR1A 3RPCA 2Q42A 2FU8A 3FCZA 4D1VA 3ADRA 4EYBA 5B15A 4UBQA 5DPXA 5AEBA 4AWZA 4TYFA 5EV8A 4C1EA 3IEKA 4KEQA 3BC2A 1X8HA 3I14A 1K07A 5LS3A 2Y8BA 3P2UA 2BG8A 4F6HA 1DDKA 5K0WA 5LCAA 4ZO2A 1JJTA 3IOGA 5EVBA 2Q0IA 5B1UA 3R2UA 3PY5A 4EY2A 5ACRA 1HLKA 3DH8A 3I13A 1P9EA 3ZWFA 3AJ3A
chains in the Genus database with same CATH superfamily
4NQ5A 1WUPA 4ZO3A 5EVKA 4D1TA 3IE2A 4AX0B 5A0TA 4ZEJA 2P97A 5AHRA 3SFPA 4TZBA 5ACSA 4DILA 4V0HA 5AXRA 3FAIA 3QH8A 4C1DA 1BVTA 4GCWA 4FR7A 4PVTA 4AWYB 1X8GA 2WYMA 4UWOB 1DXKA 1VJNA 2ZO4A 4GYQA 4GYUA 1YCFA 2DKFA 3PG4A 2NZEA 4XWWA 5FQCA 1E5DA 1XTOA 3RKJA 1QH3A 2FU7A 2I7XA 3X2ZA 5ACTA 3TP9A 2BGAA 2BG8B 5AIJA 2A7MA 3SD9A 5ACXA 4Z7RA 4RAMA 3BV6A 2P4ZA 2I7VA 4U4LA 1VMEA 2QDSA 3JXPA 1X8IA 5ACWA 4LE6A 3T3OA 1DD6A 4J5FA 5LMCA 2Y87A 3ZNBA 3SPUA 3DHCA 2GFKA 1KO2A 5A0VA 2Q9UA 4HL2A 2HB9A 2BG7A 4C09A 3WXCA 3A4YA 3BK1A 2GCUA 1XM8A 1WUOA 5HISA 2M5DA 2YNVB 1Y44A 2YHEA 4AX1B 5K4NA 4C1GA 3H3EA 4UA4A 3SBLA 2QDTA 4DIKA 4RL0A 2BC2A 1MQOA 4UWPB 2BTNA 4BP0A 5ACPA 3ZR9A 2OHJA 2CFUA 2FHXB 4D1WA 4TZFA 5KIKA 5EW0A 4F6ZA 1A8TA 2NZFA 5HIQA 3AF5A 5LLDA 4RM5A 2CG3A 4FEKA 4AV7A 3F9OA 3G1PA 4D02A 3VPEA 1A7TA 2YNVA 2BFLA 5AJLA 4B87A 2AIOA 2Q0JA 2BFKA 4YSBA 3DHAA 4RL2A 4XWTA 4WD6A 5HIPA 5LCFA 2FHXA 4NURA 4NQ4A 3X2XA 3X2YA 1ZTCA 3BK2A 4BZ3A 2YNTA 4AXHA 2H6AA 4C1HA 3IE1A 2XF4A 2YNWA 2WYLA 3ZQ4A 4Z6XA 5EH9A 5HH4A 2BFZA 4C1CA 3Q6VA 4EFZA 2R2DA 3L6NA 2WHGA 2GFJA 5ACVA 2ZNBA 4J5HA 3AF6A 5K4KA 5B3RA 4NQ6A 4UWSB 5KILA 5LSCA 5LM6A 1BC2A 3KNSA 1VGNA 2AZ4A 1M2XA 4PVOA 1SMLA 2YNUA 4RBSA 1KO3A 3IOFA 4RAWA 3SW3A 3KNRA 4Z5ZA 3T9MA 4HL1A 2QJSA 3RKKA 2FM6A 2NXAA 3DHBA 4Z67A 1KR3A 4HKYA 2BG6A 5ACQA 2CBNA 4ZNBA 4H0DA 5ACUA 4P62A 4NQ2A 4YSLA 2E7YA 5A5ZA 4JO0A 4EXSA 3I15A 3MD7A 5EV6A 3IDZA 2Y8AA 3ESHA 2FU6A 5K4MA 5FQAA 2YCBA 1ZNBA 2UYXA 3S0ZA 1JJEA 5EVDA 4AD9A 5FQBA 2VW8A 1WRAA 2P18A 4XUKA 2OHHA 5HH6A 4TYTA 4CHLA 2YNTB 2WRSA 4O98A 2WYMC 5EWAA 4EXYA 2GKLA 4D1UA 5IQKA 4FSBA 5HIOA 4Z5YA 2BR6A 3LVZA 3KL7A 2BFZB 5HH5A 1ZKPA 1WW1A 3X30A 2DOOA 2ZWRA 5AHOA 5EHTA 1YCHA 2P1EA 4EYLA 1JT1A 3I0VA 4TZ9A 2GMNA 4TZEA 1L9YA 1BMCA 3T3NA 2FK6A 3PY6A 4Z60A 2YZ3A 5A87A 5AXOA 2CG2A 3IELA 4C1FA 3VQZA 2BMIA 3IE0A 4YSKA 4UWRB 2BIBA 3IEMA 2FU9A 1QH5A 3SRXA 2M5CA 5LCHA 2NYPA 1YCGA 2OHIA 5LE1A 2QINA 2ZZIA 2I7TA 4UAMA 2BG2A 3I11A 2QEDA 4EYFA 5AYAA 4KEPA 2XR1A 3RPCA 2Q42A 2FU8A 3FCZA 4D1VA 3ADRA 2CFZA 4EYBA 5B15A 4UBQA 5DPXA 5AEBA 4AWZA 4TYFA 5A23A 5EV8A 4C1EA 3IEKA 4KEQA 3BC2A 1X8HA 3I14A 1K07A 5LS3A 4PDXA 2Y8BA 3P2UA 2BG8A 4F6HA 1DDKA 5K0WA 5LCAA 4ZO2A 1JJTA 3IOGA 5EVBA 2Q0IA 5B1UA 3R2UA 3PY5A 4EY2A 5ACRA 1HLKA 3DH8A 3I13A 1P9EA 3ZWFA 3AJ3A
chains in the Genus database with same CATH topology
4NQ5A 1WUPA 4ZO3A 5EVKA 4D1TA 3IE2A 4AX0B 5A0TA 4ZEJA 2P97A 5AHRA 3SFPA 4TZBA 5ACSA 4DILA 4V0HA 5AXRA 3FAIA 3QH8A 4C1DA 1BVTA 4GCWA 4FR7A 4PVTA 4AWYB 1X8GA 2WYMA 4UWOB 1DXKA 1VJNA 2ZO4A 4GYQA 4GYUA 1YCFA 2DKFA 3PG4A 2NZEA 4XWWA 5FQCA 1E5DA 1XTOA 3RKJA 1QH3A 2FU7A 2I7XA 3X2ZA 5ACTA 3TP9A 2BGAA 2BG8B 2A7MA 3SD9A 5ACXA 4Z7RA 4RAMA 3BV6A 2P4ZA 2I7VA 4U4LA 1VMEA 2QDSA 3JXPA 1X8IA 5ACWA 4LE6A 3T3OA 1DD6A 4J5FA 5LMCA 2Y87A 3ZNBA 3SPUA 3DHCA 2GFKA 1KO2A 5A0VA 2Q9UA 4HL2A 2HB9A 2BG7A 4C09A 3WXCA 3A4YA 3BK1A 2GCUA 1XM8A 1WUOA 5HISA 2M5DA 2YNVB 1Y44A 4AX1B 5K4NA 4C1GA 3H3EA 4UA4A 3SBLA 2QDTA 4DIKA 4RL0A 2BC2A 1MQOA 4UWPB 2BTNA 4BP0A 5ACPA 3ZR9A 2OHJA 2FHXB 4D1WA 4TZFA 5KIKA 5EW0A 4F6ZA 1A8TA 2NZFA 5HIQA 3AF5A 5LLDA 4RM5A 4FEKA 3F9OA 3G1PA 4D02A 3VPEA 1A7TA 2YNVA 2BFLA 4B87A 2AIOA 2Q0JA 2BFKA 4YSBA 3DHAA 4RL2A 4XWTA 4WD6A 5HIPA 5LCFA 2FHXA 4NQ4A 3X2YA 3X2XA 1ZTCA 3BK2A 4BZ3A 2YNTA 2H6AA 4C1HA 3IE1A 2XF4A 2YNWA 2WYLA 3ZQ4A 4Z6XA 5EH9A 5HH4A 2BFZA 4C1CA 3Q6VA 4EFZA 2R2DA 3L6NA 2WHGA 2GFJA 5ACVA 2ZNBA 4J5HA 3AF6A 5K4KA 5B3RA 4NQ6A 4UWSB 5KILA 5LSCA 5LM6A 1BC2A 3KNSA 1VGNA 2AZ4A 1M2XA 4PVOA 1SMLA 2YNUA 4RBSA 1KO3A 3IOFA 4RAWA 3SW3A 3KNRA 4Z5ZA 3T9MA 4HL1A 2QJSA 3RKKA 2FM6A 2NXAA 3DHBA 4Z67A 1KR3A 4HKYA 2BG6A 5ACQA 2CBNA 4ZNBA 4H0DA 5ACUA 4P62A 4NQ2A 4YSLA 2E7YA 5A5ZA 4JO0A 4EXSA 3I15A 3MD7A 5EV6A 3IDZA 2Y8AA 3ESHA 2FU6A 5K4MA 5FQAA 2YCBA 1ZNBA 2UYXA 3S0ZA 1JJEA 5EVDA 4AD9A 5FQBA 2VW8A 1WRAA 2P18A 4XUKA 2OHHA 5HH6A 4TYTA 4CHLA 2YNTB 2WRSA 4O98A 2WYMC 5EWAA 4EXYA 2GKLA 4D1UA 5IQKA 4FSBA 5HIOA 4Z5YA 2BR6A 3LVZA 3KL7A 2BFZB 5HH5A 1ZKPA 1WW1A 3X30A 2DOOA 2ZWRA 5AHOA 5EHTA 1YCHA 2P1EA 4EYLA 1JT1A 3I0VA 4TZ9A 2GMNA 4TZEA 1L9YA 1BMCA 3T3NA 2FK6A 3PY6A 4Z60A 2YZ3A 5A87A 5AXOA 3IELA 4C1FA 3VQZA 2BMIA 3IE0A 4YSKA 4UWRB 2BIBA 3IEMA 2FU9A 1QH5A 3SRXA 2M5CA 5LCHA 2NYPA 1YCGA 2OHIA 5LE1A 2QINA 2ZZIA 2I7TA 4UAMA 2BG2A 3I11A 2QEDA 4EYFA 5AYAA 4KEPA 2XR1A 3RPCA 2Q42A 2FU8A 3FCZA 4D1VA 3ADRA 4EYBA 5B15A 4UBQA 5DPXA 5AEBA 4AWZA 4TYFA 5EV8A 4C1EA 3IEKA 4KEQA 3BC2A 1X8HA 3I14A 1K07A 5LS3A 2Y8BA 3P2UA 2BG8A 4F6HA 1DDKA 5K0WA 5LCAA 4ZO2A 1JJTA 3IOGA 5EVBA 2Q0IA 5B1UA 3R2UA 3PY5A 4EY2A 5ACRA 1HLKA 3DH8A 3I13A 1P9EA 3ZWFA 3AJ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NQ5 A;  1WUP A;  4ZO3 A;  5EVK A;  4D1T A;  3IE2 A;  4AX0 B;  5A0T A;  4ZEJ A;  2P97 A;  5AHR A;  3SFP A;  4TZB A;  5ACS A;  4DIL A;  4V0H A;  5AXR A;  3FAI A;  3QH8 A;  4C1D A;  1BVT A;  4GCW A;  4FR7 A;  4PVT A;  4AWY B;  1X8G A;  2WYM A;  4UWO B;  1DXK A;  1VJN A;  2ZO4 A;  4GYQ A;  4GYU A;  1YCF A;  2DKF A;  3PG4 A;  2NZE A;  4XWW A;  5FQC A;  1E5D A;  1XTO A;  3RKJ A;  1QH3 A;  2FU7 A;  2I7X A;  3X2Z A;  5ACT A;  3TP9 A;  2BGA A;  2BG8 B;  2A7M A;  3SD9 A;  5ACX A;  4Z7R A;  4RAM A;  3BV6 A;  2P4Z A;  2I7V A;  4U4L A;  1VME A;  2QDS A;  3JXP A;  1X8I A;  5ACW A;  4LE6 A;  3T3O A;  1DD6 A;  4J5F A;  5LMC A;  2Y87 A;  3ZNB A;  3SPU A;  3DHC A;  2GFK A;  1KO2 A;  5A0V A;  2Q9U A;  4HL2 A;  2HB9 A;  2BG7 A;  4C09 A;  3WXC A;  3A4Y A;  3BK1 A;  2GCU A;  1XM8 A;  1WUO A;  5HIS A;  2M5D A;  2YNV B;  1Y44 A;  4AX1 B;  5K4N A;  4C1G A;  3H3E A;  4UA4 A;  3SBL A;  2QDT A;  4DIK A;  4RL0 A;  2BC2 A;  1MQO A;  4UWP B;  2BTN A;  4BP0 A;  5ACP A;  3ZR9 A;  2OHJ A;  2FHX B;  4D1W A;  4TZF A;  5KIK A;  5EW0 A;  4F6Z A;  1A8T A;  2NZF A;  5HIQ A;  3AF5 A;  5LLD A;  4RM5 A;  4FEK A;  3F9O A;  3G1P A;  4D02 A;  3VPE A;  1A7T A;  2YNV A;  2BFL A;  4B87 A;  2AIO A;  2Q0J A;  2BFK A;  4YSB A;  3DHA A;  4RL2 A;  4XWT A;  4WD6 A;  5HIP A;  5LCF A;  2FHX A;  4NQ4 A;  3X2Y A;  3X2X A;  1ZTC A;  3BK2 A;  4BZ3 A;  2YNT A;  2H6A A;  4C1H A;  3IE1 A;  2XF4 A;  2YNW A;  2WYL A;  3ZQ4 A;  4Z6X A;  5EH9 A;  5HH4 A;  2BFZ A;  4C1C A;  3Q6V A;  4EFZ A;  2R2D A;  3L6N A;  2WHG A;  2GFJ A;  5ACV A;  2ZNB A;  4J5H A;  3AF6 A;  5K4K A;  5B3R A;  4NQ6 A;  4UWS B;  5KIL A;  5LSC A;  5LM6 A;  1BC2 A;  3KNS A;  1VGN A;  2AZ4 A;  1M2X A;  4PVO A;  1SML A;  2YNU A;  4RBS A;  1KO3 A;  3IOF A;  4RAW A;  3SW3 A;  3KNR A;  4Z5Z A;  3T9M A;  4HL1 A;  2QJS A;  3RKK A;  2FM6 A;  2NXA A;  3DHB A;  4Z67 A;  1KR3 A;  4HKY A;  2BG6 A;  5ACQ A;  2CBN A;  4ZNB A;  4H0D A;  5ACU A;  4P62 A;  4NQ2 A;  4YSL A;  2E7Y A;  5A5Z A;  4JO0 A;  4EXS A;  3I15 A;  3MD7 A;  5EV6 A;  3IDZ A;  2Y8A A;  3ESH A;  2FU6 A;  5K4M A;  5FQA A;  2YCB A;  1ZNB A;  2UYX A;  3S0Z A;  1JJE A;  5EVD A;  4AD9 A;  5FQB A;  2VW8 A;  1WRA A;  2P18 A;  4XUK A;  2OHH A;  5HH6 A;  4TYT A;  4CHL A;  2YNT B;  2WRS A;  4O98 A;  2WYM C;  5EWA A;  4EXY A;  2GKL A;  4D1U A;  5IQK A;  4FSB A;  5HIO A;  4Z5Y A;  2BR6 A;  3LVZ A;  3KL7 A;  2BFZ B;  5HH5 A;  1ZKP A;  1WW1 A;  3X30 A;  2DOO A;  2ZWR A;  5AHO A;  5EHT A;  1YCH A;  2P1E A;  4EYL A;  1JT1 A;  3I0V A;  4TZ9 A;  2GMN A;  4TZE A;  1L9Y A;  1BMC A;  3T3N A;  2FK6 A;  3PY6 A;  4Z60 A;  2YZ3 A;  5A87 A;  5AXO A;  3IEL A;  4C1F A;  3VQZ A;  2BMI A;  3IE0 A;  4YSK A;  4UWR B;  2BIB A;  3IEM A;  2FU9 A;  1QH5 A;  3SRX A;  2M5C A;  5LCH A;  2NYP A;  1YCG A;  2OHI A;  5LE1 A;  2QIN A;  2ZZI A;  2I7T A;  4UAM A;  2BG2 A;  3I11 A;  2QED A;  4EYF A;  5AYA A;  4KEP A;  2XR1 A;  3RPC A;  2Q42 A;  2FU8 A;  3FCZ A;  4D1V A;  3ADR A;  4EYB A;  5B15 A;  4UBQ A;  5DPX A;  5AEB A;  4AWZ A;  4TYF A;  5EV8 A;  4C1E A;  3IEK A;  4KEQ A;  3BC2 A;  1X8H A;  3I14 A;  1K07 A;  5LS3 A;  2Y8B A;  3P2U A;  2BG8 A;  4F6H A;  1DDK A;  5K0W A;  5LCA A;  4ZO2 A;  1JJT A;  3IOG A;  5EVB A;  2Q0I A;  5B1U A;  3R2U A;  3PY5 A;  4EY2 A;  5ACR A;  1HLK A;  3DH8 A;  3I13 A;  1P9E A;  3ZWF A;  3AJ3 A; 
#chains in the Genus database with same CATH topology
 4NQ5 A;  1WUP A;  4ZO3 A;  5EVK A;  4D1T A;  3IE2 A;  4AX0 B;  5A0T A;  4ZEJ A;  2P97 A;  5AHR A;  3SFP A;  4TZB A;  5ACS A;  4DIL A;  4V0H A;  5AXR A;  3FAI A;  3QH8 A;  4C1D A;  1BVT A;  4GCW A;  4FR7 A;  4PVT A;  4AWY B;  1X8G A;  2WYM A;  4UWO B;  1DXK A;  1VJN A;  2ZO4 A;  4GYQ A;  4GYU A;  1YCF A;  2DKF A;  3PG4 A;  2NZE A;  4XWW A;  5FQC A;  1E5D A;  1XTO A;  3RKJ A;  1QH3 A;  2FU7 A;  2I7X A;  3X2Z A;  5ACT A;  3TP9 A;  2BGA A;  2BG8 B;  5AIJ A;  2A7M A;  3SD9 A;  5ACX A;  4Z7R A;  4RAM A;  3BV6 A;  2P4Z A;  2I7V A;  4U4L A;  1VME A;  2QDS A;  3JXP A;  1X8I A;  5ACW A;  4LE6 A;  3T3O A;  1DD6 A;  4J5F A;  5LMC A;  2Y87 A;  3ZNB A;  3SPU A;  3DHC A;  2GFK A;  1KO2 A;  5A0V A;  2Q9U A;  4HL2 A;  2HB9 A;  2BG7 A;  4C09 A;  3WXC A;  3A4Y A;  3BK1 A;  2GCU A;  1XM8 A;  1WUO A;  5HIS A;  2M5D A;  2YNV B;  1Y44 A;  2YHE A;  4AX1 B;  5K4N A;  4C1G A;  3H3E A;  4UA4 A;  3SBL A;  2QDT A;  4DIK A;  4RL0 A;  2BC2 A;  1MQO A;  4UWP B;  2BTN A;  4BP0 A;  5ACP A;  3ZR9 A;  2OHJ A;  2CFU A;  2FHX B;  4D1W A;  4TZF A;  5KIK A;  5EW0 A;  4F6Z A;  1A8T A;  2NZF A;  5HIQ A;  3AF5 A;  5LLD A;  4RM5 A;  2CG3 A;  4FEK A;  4AV7 A;  3F9O A;  3G1P A;  4D02 A;  3VPE A;  1A7T A;  2YNV A;  2BFL A;  5AJL A;  4B87 A;  2AIO A;  2Q0J A;  2BFK A;  4YSB A;  3DHA A;  4RL2 A;  4XWT A;  4WD6 A;  5HIP A;  5LCF A;  2FHX A;  4NUR A;  4NQ4 A;  3X2X A;  3X2Y A;  1ZTC A;  3BK2 A;  4BZ3 A;  2YNT A;  4AXH A;  2H6A A;  4C1H A;  3IE1 A;  2XF4 A;  2YNW A;  2WYL A;  3ZQ4 A;  4Z6X A;  5EH9 A;  5HH4 A;  2BFZ A;  4C1C A;  3Q6V A;  4EFZ A;  2R2D A;  3L6N A;  2WHG A;  2GFJ A;  5ACV A;  2ZNB A;  4J5H A;  3AF6 A;  5K4K A;  5B3R A;  4NQ6 A;  4UWS B;  5KIL A;  5LSC A;  5LM6 A;  1BC2 A;  3KNS A;  1VGN A;  2AZ4 A;  1M2X A;  4PVO A;  1SML A;  2YNU A;  4RBS A;  1KO3 A;  3IOF A;  4RAW A;  3SW3 A;  3KNR A;  4Z5Z A;  3T9M A;  4HL1 A;  2QJS A;  3RKK A;  2FM6 A;  2NXA A;  3DHB A;  4Z67 A;  1KR3 A;  4HKY A;  2BG6 A;  5ACQ A;  2CBN A;  4ZNB A;  4H0D A;  5ACU A;  4P62 A;  4NQ2 A;  4YSL A;  2E7Y A;  5A5Z A;  4JO0 A;  4EXS A;  3I15 A;  3MD7 A;  5EV6 A;  3IDZ A;  2Y8A A;  3ESH A;  2FU6 A;  5K4M A;  5FQA A;  2YCB A;  1ZNB A;  2UYX A;  3S0Z A;  1JJE A;  5EVD A;  4AD9 A;  5FQB A;  2VW8 A;  1WRA A;  2P18 A;  4XUK A;  2OHH A;  5HH6 A;  4TYT A;  4CHL A;  2YNT B;  2WRS A;  4O98 A;  2WYM C;  5EWA A;  4EXY A;  2GKL A;  4D1U A;  5IQK A;  4FSB A;  5HIO A;  4Z5Y A;  2BR6 A;  3LVZ A;  3KL7 A;  2BFZ B;  5HH5 A;  1ZKP A;  1WW1 A;  3X30 A;  2DOO A;  2ZWR A;  5AHO A;  5EHT A;  1YCH A;  2P1E A;  4EYL A;  1JT1 A;  3I0V A;  4TZ9 A;  2GMN A;  4TZE A;  1L9Y A;  1BMC A;  3T3N A;  2FK6 A;  3PY6 A;  4Z60 A;  2YZ3 A;  5A87 A;  5AXO A;  2CG2 A;  3IEL A;  4C1F A;  3VQZ A;  2BMI A;  3IE0 A;  4YSK A;  4UWR B;  2BIB A;  3IEM A;  2FU9 A;  1QH5 A;  3SRX A;  2M5C A;  5LCH A;  2NYP A;  1YCG A;  2OHI A;  5LE1 A;  2QIN A;  2ZZI A;  2I7T A;  4UAM A;  2BG2 A;  3I11 A;  2QED A;  4EYF A;  5AYA A;  4KEP A;  2XR1 A;  3RPC A;  2Q42 A;  2FU8 A;  3FCZ A;  4D1V A;  3ADR A;  2CFZ A;  4EYB A;  5B15 A;  4UBQ A;  5DPX A;  5AEB A;  4AWZ A;  4TYF A;  5A23 A;  5EV8 A;  4C1E A;  3IEK A;  4KEQ A;  3BC2 A;  1X8H A;  3I14 A;  1K07 A;  5LS3 A;  4PDX A;  2Y8B A;  3P2U A;  2BG8 A;  4F6H A;  1DDK A;  5K0W A;  5LCA A;  4ZO2 A;  1JJT A;  3IOG A;  5EVB A;  2Q0I A;  5B1U A;  3R2U A;  3PY5 A;  4EY2 A;  5ACR A;  1HLK A;  3DH8 A;  3I13 A;  1P9E A;  3ZWF A;  3AJ3 A; 
#chains in the Genus database with same CATH homology
 4NQ5 A;  1WUP A;  4ZO3 A;  5EVK A;  4D1T A;  3IE2 A;  4AX0 B;  5A0T A;  4ZEJ A;  2P97 A;  5AHR A;  3SFP A;  4TZB A;  5ACS A;  4DIL A;  4V0H A;  5AXR A;  3FAI A;  3QH8 A;  4C1D A;  1BVT A;  4GCW A;  4FR7 A;  4PVT A;  4AWY B;  1X8G A;  2WYM A;  4UWO B;  1DXK A;  1VJN A;  2ZO4 A;  4GYQ A;  4GYU A;  1YCF A;  2DKF A;  3PG4 A;  2NZE A;  4XWW A;  5FQC A;  1E5D A;  1XTO A;  3RKJ A;  1QH3 A;  2FU7 A;  2I7X A;  3X2Z A;  5ACT A;  3TP9 A;  2BGA A;  2BG8 B;  2A7M A;  3SD9 A;  5ACX A;  4Z7R A;  4RAM A;  3BV6 A;  2P4Z A;  2I7V A;  4U4L A;  1VME A;  2QDS A;  3JXP A;  1X8I A;  5ACW A;  4LE6 A;  3T3O A;  1DD6 A;  4J5F A;  5LMC A;  2Y87 A;  3ZNB A;  3SPU A;  3DHC A;  2GFK A;  1KO2 A;  5A0V A;  2Q9U A;  4HL2 A;  2HB9 A;  2BG7 A;  4C09 A;  3WXC A;  3A4Y A;  3BK1 A;  2GCU A;  1XM8 A;  1WUO A;  5HIS A;  2M5D A;  2YNV B;  1Y44 A;  4AX1 B;  5K4N A;  4C1G A;  3H3E A;  4UA4 A;  3SBL A;  2QDT A;  4DIK A;  4RL0 A;  2BC2 A;  1MQO A;  4UWP B;  2BTN A;  4BP0 A;  5ACP A;  3ZR9 A;  2OHJ A;  2FHX B;  4D1W A;  4TZF A;  5KIK A;  5EW0 A;  4F6Z A;  1A8T A;  2NZF A;  5HIQ A;  3AF5 A;  5LLD A;  4RM5 A;  4FEK A;  3F9O A;  3G1P A;  4D02 A;  3VPE A;  1A7T A;  2YNV A;  2BFL A;  4B87 A;  2AIO A;  2Q0J A;  2BFK A;  4YSB A;  3DHA A;  4RL2 A;  4XWT A;  4WD6 A;  5HIP A;  5LCF A;  2FHX A;  4NQ4 A;  3X2Y A;  3X2X A;  1ZTC A;  3BK2 A;  4BZ3 A;  2YNT A;  2H6A A;  4C1H A;  3IE1 A;  2XF4 A;  2YNW A;  2WYL A;  3ZQ4 A;  4Z6X A;  5EH9 A;  5HH4 A;  2BFZ A;  4C1C A;  3Q6V A;  4EFZ A;  2R2D A;  3L6N A;  2WHG A;  2GFJ A;  5ACV A;  2ZNB A;  4J5H A;  3AF6 A;  5K4K A;  5B3R A;  4NQ6 A;  4UWS B;  5KIL A;  5LSC A;  5LM6 A;  1BC2 A;  3KNS A;  1VGN A;  2AZ4 A;  1M2X A;  4PVO A;  1SML A;  2YNU A;  4RBS A;  1KO3 A;  3IOF A;  4RAW A;  3SW3 A;  3KNR A;  4Z5Z A;  3T9M A;  4HL1 A;  2QJS A;  3RKK A;  2FM6 A;  2NXA A;  3DHB A;  4Z67 A;  1KR3 A;  4HKY A;  2BG6 A;  5ACQ A;  2CBN A;  4ZNB A;  4H0D A;  5ACU A;  4P62 A;  4NQ2 A;  4YSL A;  2E7Y A;  5A5Z A;  4JO0 A;  4EXS A;  3I15 A;  3MD7 A;  5EV6 A;  3IDZ A;  2Y8A A;  3ESH A;  2FU6 A;  5K4M A;  5FQA A;  2YCB A;  1ZNB A;  2UYX A;  3S0Z A;  1JJE A;  5EVD A;  4AD9 A;  5FQB A;  2VW8 A;  1WRA A;  2P18 A;  4XUK A;  2OHH A;  5HH6 A;  4TYT A;  4CHL A;  2YNT B;  2WRS A;  4O98 A;  2WYM C;  5EWA A;  4EXY A;  2GKL A;  4D1U A;  5IQK A;  4FSB A;  5HIO A;  4Z5Y A;  2BR6 A;  3LVZ A;  3KL7 A;  2BFZ B;  5HH5 A;  1ZKP A;  1WW1 A;  3X30 A;  2DOO A;  2ZWR A;  5AHO A;  5EHT A;  1YCH A;  2P1E A;  4EYL A;  1JT1 A;  3I0V A;  4TZ9 A;  2GMN A;  4TZE A;  1L9Y A;  1BMC A;  3T3N A;  2FK6 A;  3PY6 A;  4Z60 A;  2YZ3 A;  5A87 A;  5AXO A;  3IEL A;  4C1F A;  3VQZ A;  2BMI A;  3IE0 A;  4YSK A;  4UWR B;  2BIB A;  3IEM A;  2FU9 A;  1QH5 A;  3SRX A;  2M5C A;  5LCH A;  2NYP A;  1YCG A;  2OHI A;  5LE1 A;  2QIN A;  2ZZI A;  2I7T A;  4UAM A;  2BG2 A;  3I11 A;  2QED A;  4EYF A;  5AYA A;  4KEP A;  2XR1 A;  3RPC A;  2Q42 A;  2FU8 A;  3FCZ A;  4D1V A;  3ADR A;  4EYB A;  5B15 A;  4UBQ A;  5DPX A;  5AEB A;  4AWZ A;  4TYF A;  5EV8 A;  4C1E A;  3IEK A;  4KEQ A;  3BC2 A;  1X8H A;  3I14 A;  1K07 A;  5LS3 A;  2Y8B A;  3P2U A;  2BG8 A;  4F6H A;  1DDK A;  5K0W A;  5LCA A;  4ZO2 A;  1JJT A;  3IOG A;  5EVB A;  2Q0I A;  5B1U A;  3R2U A;  3PY5 A;  4EY2 A;  5ACR A;  1HLK A;  3DH8 A;  3I13 A;  1P9E A;  3ZWF A;  3AJ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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