5ACXA

Vim-2-2, discovery of novel inhibitor scaffolds against the metallo- beta-lactamase vim-2 by spr based fragment screening
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
233
structure length
231
Chain Sequence
GEYPTVSEIPVGEVRLYQIADGVWSHIATQSFDGAVYPSNGLIVRDGDELLLIDTAWGAKNTAALLAEIEKQIGLPVTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSSSGDAVRFGPVELFYPGAAHSTDNLVVYVPSASVLYGGAIYELSTSAGNVADADLAEWPTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Inhibitor Scaffolds Against the Metallo-Beta-Lactamase Vim-2 by Spr Based Fragment Screening
pubmed doi rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase
molecule keywords BETA-LACTAMASE
total genus 77
structure length 231
sequence length 233
chains with identical sequence B
ec nomenclature ec 3.5.2.6: Beta-lactamase.
pdb deposition date 2015-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00753 Lactamase_B Metallo-beta-lactamase superfamily
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.15.10 Alpha Beta 4-Layer Sandwich Metallo-beta-lactamase; Chain A Ribonuclease Z/Hydroxyacylglutathione hydrolase-like 5acxA00
5LS3A 4EY2A 3AF6A 5A0VA 1WW1A 4RL0A 2A7MA 3X2XA 1X8GA 2QDSA 5HISA 2NZEA 5HIOA 4NQ2A 3I11A 5A87A 1MQOA 5A5ZA 2FU6A 4RAMA 1X8HA 2BTNA 3DHBA 4C1FA 1BMCA 4F6HA 3R2UA 4FEKA 4Z7RA 1JJEA 2QJSA 5ACWA 4RM5A 4C09A 2ZNBA 4PVTA 4UWSB 5HIQA 3IOGA 5ACRA 4HL2A 5LSCA 2YZ3A 4LE6A 5KILA 3RKJA 3ZR9A 2WHGA 4YSBA 4AWZA 3BV6A 5AEBA 5AYAA 4TYTA 3I14A 3I15A 4U4LA 4EYBA 4HKYA 5HH6A 2BG8B 4Z6XA 3RKKA 2GCUA 2XR1A 3LVZA 3BK2A 4UAMA 4ZNBA 5LMCA 1Y44A 2I7TA 4FSBA 4EXYA 5ACSA 2DOOA 4AX1B 5B15A 2Q0IA 5HH4A 5FQCA 5K0WA 2VW8A 3SRXA 2ZO4A 4D02A 1L9YA 2Q9UA 2GKLA 1QH5A 2Q0JA 2QEDA 2M5DA 4GYQA 2BG2A 5EV6A 5FQBA 4YSLA 1DD6A 2YNVB 3PG4A 3AF5A 5LM6A 4JO0A 1SMLA 1A8TA 3PY5A 2I7XA 2NXAA 3IOFA 4C1GA 2R2DA 5LE1A 2BG7A 5AXOA 2NYPA 2YCBA 3TP9A 2HB9A 5LCFA 5EV8A 2BFKA 5IQKA 1QH3A 2E7YA 2OHHA 4EXSA 2FHXB 3VQZA 4CHLA 4C1HA 5EVDA 5ACTA 5LCHA 5ACQA 4FR7A 3I0VA 5KIKA 4Z5ZA 4UWRB 1KR3A 5DPXA 3ADRA 5ACPA 3A4YA 1XTOA 2M5CA 3KNRA 4Z5YA 3IE0A 5AXRA 5A0TA 1X8IA 4BZ3A 3T3NA 2UYXA 3F9OA 2P18A 4B87A 4UWOB 4XUKA 3IELA 2GFJA 1ZTCA 5K4KA 4YSKA 4C1DA 2WYMC 3IEMA 4UBQA 2YNWA 3X2YA 2P4ZA 3ESHA 3ZWFA 4XWWA 4NQ5A 4KEQA 2FK6A 3X30A 2WYLA 3DHAA 3IE1A 4EYFA 5ACUA 1BC2A 3Q6VA 3ZQ4A 4O98A 4AD9A 2NZFA 3SPUA 5B1UA 1WUPA 3KL7A 4RBSA 5EVBA 1JT1A 5B3RA 4GYUA 1VJNA 2AZ4A 2BIBA 3BK1A 4UWPB 3T3OA 5EW0A 1YCGA 4NQ6A 4J5FA 2YNTA 1P9EA 1WRAA 1YCHA 5K4MA 2BGAA 4ZO3A 3IE2A 4P62A 4NQ4A 1WUOA 2Y8BA 2BR6A 3RPCA 2XF4A 3H3EA 5EVKA 3QH8A 2BFZB 4D1VA 2BFZA 1ZKPA 1BVTA 4H0DA 2OHIA 5K4NA 2FHXA 4EFZA 4HL1A 3G1PA 4Z60A 1XM8A 4DIKA 3FAIA 3MD7A 2OHJA 4UA4A 4BP0A 3T9MA 5EH9A 2FU8A 2I7VA 2BFLA 3S0ZA 2DKFA 5FQAA 2WYMA 4GCWA 4TZFA 1DXKA 3I13A 2QDTA 4ZEJA 1VMEA 3JXPA 2Y8AA 2YNUA 3VPEA 5ACXA 1HLKA 2BG6A 5LCAA 2AIOA 1YCFA 3X2ZA 4RL2A 3SFPA 3AJ3A 3FCZA 2BC2A 4DILA 4RAWA 1KO3A 4XWTA 2FU7A 2ZZIA 5EWAA 5HH5A 3KNSA 5AHOA 4F6ZA 2FM6A 4KEPA 1A7TA 4V0HA 4PVOA 4C1EA 3DHCA 5ACVA 4Z67A 3L6NA 4EYLA 4C1CA 4TZBA 2BMIA 4D1WA 1M2XA 3P2UA 1VGNA 4TZ9A 3SW3A 1DDKA 4TYFA 3SD9A 2ZWRA 4AWYB 2QINA 5HIPA 1JJTA 2Q42A 3BC2A 2H6AA 2YNTB 2CBNA 5AHRA 3SBLA 2GFKA 3DH8A 4TZEA 1ZNBA 3IEKA 3PY6A 2FU9A 4WD6A 4D1TA 1E5DA 1K07A 3WXCA 2P97A 4J5HA 2WRSA 2YNVA 4AX0B 3IDZA 2GMNA 3ZNBA 2P1EA 5LLDA 5EHTA 2BG8A 1KO2A 4D1UA 2Y87A 4ZO2A
chains in the Genus database with same CATH superfamily
5LS3A 4EY2A 3AF6A 5A0VA 1WW1A 4RL0A 2A7MA 3X2XA 1X8GA 2QDSA 5HISA 2NZEA 5HIOA 4NQ2A 3I11A 2CG3A 5A87A 1MQOA 5A5ZA 2FU6A 4RAMA 1X8HA 2BTNA 3DHBA 4C1FA 1BMCA 4F6HA 3R2UA 4FEKA 4Z7RA 1JJEA 2QJSA 5ACWA 4RM5A 4C09A 2ZNBA 4PVTA 4UWSB 5HIQA 3IOGA 5ACRA 4HL2A 5LSCA 2YZ3A 4LE6A 5KILA 3RKJA 3ZR9A 2WHGA 4YSBA 4AWZA 3BV6A 5AEBA 5AYAA 4TYTA 3I14A 3I15A 4U4LA 4EYBA 4HKYA 5HH6A 2BG8B 4Z6XA 3RKKA 2GCUA 2XR1A 3LVZA 3BK2A 4UAMA 4ZNBA 5LMCA 1Y44A 2I7TA 4FSBA 4EXYA 5ACSA 2DOOA 4AX1B 5B15A 2Q0IA 5HH4A 5FQCA 5K0WA 5A23A 2VW8A 3SRXA 2ZO4A 4D02A 1L9YA 2Q9UA 2GKLA 1QH5A 2Q0JA 2QEDA 2M5DA 4GYQA 2BG2A 5EV6A 5FQBA 4YSLA 1DD6A 2YNVB 3PG4A 3AF5A 5LM6A 4JO0A 1SMLA 1A8TA 3PY5A 2I7XA 2NXAA 3IOFA 4C1GA 2R2DA 5LE1A 2BG7A 5AXOA 2NYPA 2YCBA 3TP9A 2HB9A 5LCFA 5EV8A 2BFKA 5IQKA 1QH3A 2E7YA 2OHHA 4EXSA 2FHXB 3VQZA 4CHLA 4C1HA 5EVDA 5ACTA 5LCHA 5ACQA 4FR7A 3I0VA 5KIKA 4Z5ZA 5AJLA 4UWRB 1KR3A 5DPXA 3ADRA 5ACPA 3A4YA 1XTOA 2M5CA 3KNRA 4Z5YA 3IE0A 5AXRA 5A0TA 1X8IA 4BZ3A 3T3NA 2UYXA 3F9OA 2P18A 2CFUA 4B87A 4UWOB 4XUKA 3IELA 2GFJA 1ZTCA 5K4KA 4YSKA 4C1DA 2WYMC 3IEMA 4UBQA 2YNWA 3X2YA 2P4ZA 3ESHA 3ZWFA 4XWWA 4NQ5A 4KEQA 2FK6A 3X30A 2WYLA 3DHAA 3IE1A 4EYFA 5ACUA 1BC2A 3Q6VA 3ZQ4A 4O98A 4AD9A 2NZFA 3SPUA 5B1UA 1WUPA 3KL7A 4RBSA 5EVBA 1JT1A 5B3RA 4GYUA 1VJNA 2AZ4A 2BIBA 3BK1A 4UWPB 4AV7A 3T3OA 5EW0A 1YCGA 4NQ6A 4J5FA 2YNTA 1P9EA 1WRAA 1YCHA 5K4MA 2BGAA 4ZO3A 3IE2A 4P62A 4NQ4A 1WUOA 2Y8BA 2BR6A 3RPCA 2XF4A 3H3EA 5EVKA 3QH8A 2BFZB 4D1VA 4PDXA 2BFZA 1ZKPA 1BVTA 4H0DA 2OHIA 5K4NA 2FHXA 4EFZA 4HL1A 3G1PA 4Z60A 1XM8A 4DIKA 3FAIA 3MD7A 2OHJA 4UA4A 4BP0A 3T9MA 5EH9A 2FU8A 2I7VA 2BFLA 3S0ZA 2DKFA 5FQAA 2WYMA 4GCWA 4TZFA 1DXKA 3I13A 2QDTA 4ZEJA 1VMEA 3JXPA 2Y8AA 4AXHA 2YNUA 3VPEA 2CFZA 5ACXA 1HLKA 2BG6A 5LCAA 2AIOA 1YCFA 3X2ZA 4RL2A 3SFPA 3AJ3A 3FCZA 2BC2A 4DILA 4RAWA 1KO3A 4XWTA 2FU7A 2ZZIA 5EWAA 5HH5A 3KNSA 5AHOA 4F6ZA 5AIJA 2FM6A 4KEPA 1A7TA 4V0HA 4PVOA 4C1EA 3DHCA 5ACVA 4Z67A 3L6NA 4EYLA 4C1CA 4TZBA 2CG2A 2BMIA 4D1WA 1M2XA 3P2UA 1VGNA 4TZ9A 2YHEA 3SW3A 1DDKA 4TYFA 3SD9A 2ZWRA 4AWYB 2QINA 5HIPA 1JJTA 2Q42A 3BC2A 2H6AA 2YNTB 2CBNA 5AHRA 3SBLA 2GFKA 3DH8A 4TZEA 1ZNBA 3IEKA 3PY6A 2FU9A 4WD6A 4D1TA 1E5DA 1K07A 3WXCA 2P97A 4J5HA 2WRSA 2YNVA 4AX0B 3IDZA 2GMNA 3ZNBA 2P1EA 5LLDA 5EHTA 2BG8A 1KO2A 4D1UA 4NURA 2Y87A 4ZO2A
chains in the Genus database with same CATH topology
5LS3A 4EY2A 3AF6A 5A0VA 1WW1A 4RL0A 2A7MA 3X2XA 1X8GA 2QDSA 5HISA 2NZEA 5HIOA 4NQ2A 3I11A 5A87A 1MQOA 5A5ZA 2FU6A 4RAMA 1X8HA 2BTNA 3DHBA 4C1FA 1BMCA 4F6HA 3R2UA 4FEKA 4Z7RA 1JJEA 2QJSA 5ACWA 4RM5A 4C09A 2ZNBA 4PVTA 4UWSB 5HIQA 3IOGA 5ACRA 4HL2A 5LSCA 2YZ3A 4LE6A 5KILA 3RKJA 3ZR9A 2WHGA 4YSBA 4AWZA 3BV6A 5AEBA 5AYAA 4TYTA 3I14A 3I15A 4U4LA 4EYBA 4HKYA 5HH6A 2BG8B 4Z6XA 3RKKA 2GCUA 2XR1A 3LVZA 3BK2A 4UAMA 4ZNBA 5LMCA 1Y44A 2I7TA 4FSBA 4EXYA 5ACSA 2DOOA 4AX1B 5B15A 2Q0IA 5HH4A 5FQCA 5K0WA 2VW8A 3SRXA 2ZO4A 4D02A 1L9YA 2Q9UA 2GKLA 1QH5A 2Q0JA 2QEDA 2M5DA 4GYQA 2BG2A 5EV6A 5FQBA 4YSLA 1DD6A 2YNVB 3PG4A 3AF5A 5LM6A 4JO0A 1SMLA 1A8TA 3PY5A 2I7XA 2NXAA 3IOFA 4C1GA 2R2DA 5LE1A 2BG7A 5AXOA 2NYPA 2YCBA 3TP9A 2HB9A 5LCFA 5EV8A 2BFKA 5IQKA 1QH3A 2E7YA 2OHHA 4EXSA 2FHXB 3VQZA 4CHLA 4C1HA 5EVDA 5ACTA 5LCHA 5ACQA 4FR7A 3I0VA 5KIKA 4Z5ZA 4UWRB 1KR3A 5DPXA 3ADRA 5ACPA 3A4YA 1XTOA 2M5CA 3KNRA 4Z5YA 3IE0A 5AXRA 5A0TA 1X8IA 4BZ3A 3T3NA 2UYXA 3F9OA 2P18A 4B87A 4UWOB 4XUKA 3IELA 2GFJA 1ZTCA 5K4KA 4YSKA 4C1DA 2WYMC 3IEMA 4UBQA 2YNWA 3X2YA 2P4ZA 3ESHA 3ZWFA 4XWWA 4NQ5A 4KEQA 2FK6A 3X30A 2WYLA 3DHAA 3IE1A 4EYFA 5ACUA 1BC2A 3Q6VA 3ZQ4A 4O98A 4AD9A 2NZFA 3SPUA 5B1UA 1WUPA 3KL7A 4RBSA 5EVBA 1JT1A 5B3RA 4GYUA 1VJNA 2AZ4A 2BIBA 3BK1A 4UWPB 3T3OA 5EW0A 1YCGA 4NQ6A 4J5FA 2YNTA 1P9EA 1WRAA 1YCHA 5K4MA 2BGAA 4ZO3A 3IE2A 4P62A 4NQ4A 1WUOA 2Y8BA 2BR6A 3RPCA 2XF4A 3H3EA 5EVKA 3QH8A 2BFZB 4D1VA 2BFZA 1ZKPA 1BVTA 4H0DA 2OHIA 5K4NA 2FHXA 4EFZA 4HL1A 3G1PA 4Z60A 1XM8A 4DIKA 3FAIA 3MD7A 2OHJA 4UA4A 4BP0A 3T9MA 5EH9A 2FU8A 2I7VA 2BFLA 3S0ZA 2DKFA 5FQAA 2WYMA 4GCWA 4TZFA 1DXKA 3I13A 2QDTA 4ZEJA 1VMEA 3JXPA 2Y8AA 2YNUA 3VPEA 5ACXA 1HLKA 2BG6A 5LCAA 2AIOA 1YCFA 3X2ZA 4RL2A 3SFPA 3AJ3A 3FCZA 2BC2A 4DILA 4RAWA 1KO3A 4XWTA 2FU7A 2ZZIA 5EWAA 5HH5A 3KNSA 5AHOA 4F6ZA 2FM6A 4KEPA 1A7TA 4V0HA 4PVOA 4C1EA 3DHCA 5ACVA 4Z67A 3L6NA 4EYLA 4C1CA 4TZBA 2BMIA 4D1WA 1M2XA 3P2UA 1VGNA 4TZ9A 3SW3A 1DDKA 4TYFA 3SD9A 2ZWRA 4AWYB 2QINA 5HIPA 1JJTA 2Q42A 3BC2A 2H6AA 2YNTB 2CBNA 5AHRA 3SBLA 2GFKA 3DH8A 4TZEA 1ZNBA 3IEKA 3PY6A 2FU9A 4WD6A 4D1TA 1E5DA 1K07A 3WXCA 2P97A 4J5HA 2WRSA 2YNVA 4AX0B 3IDZA 2GMNA 3ZNBA 2P1EA 5LLDA 5EHTA 2BG8A 1KO2A 4D1UA 2Y87A 4ZO2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5LS3 A;  4EY2 A;  3AF6 A;  5A0V A;  1WW1 A;  4RL0 A;  2A7M A;  3X2X A;  1X8G A;  2QDS A;  5HIS A;  2NZE A;  5HIO A;  4NQ2 A;  3I11 A;  5A87 A;  1MQO A;  5A5Z A;  2FU6 A;  4RAM A;  1X8H A;  2BTN A;  3DHB A;  4C1F A;  1BMC A;  4F6H A;  3R2U A;  4FEK A;  4Z7R A;  1JJE A;  2QJS A;  5ACW A;  4RM5 A;  4C09 A;  2ZNB A;  4PVT A;  4UWS B;  5HIQ A;  3IOG A;  5ACR A;  4HL2 A;  5LSC A;  2YZ3 A;  4LE6 A;  5KIL A;  3RKJ A;  3ZR9 A;  2WHG A;  4YSB A;  4AWZ A;  3BV6 A;  5AEB A;  5AYA A;  4TYT A;  3I14 A;  3I15 A;  4U4L A;  4EYB A;  4HKY A;  5HH6 A;  2BG8 B;  4Z6X A;  3RKK A;  2GCU A;  2XR1 A;  3LVZ A;  3BK2 A;  4UAM A;  4ZNB A;  5LMC A;  1Y44 A;  2I7T A;  4FSB A;  4EXY A;  5ACS A;  2DOO A;  4AX1 B;  5B15 A;  2Q0I A;  5HH4 A;  5FQC A;  5K0W A;  2VW8 A;  3SRX A;  2ZO4 A;  4D02 A;  1L9Y A;  2Q9U A;  2GKL A;  1QH5 A;  2Q0J A;  2QED A;  2M5D A;  4GYQ A;  2BG2 A;  5EV6 A;  5FQB A;  4YSL A;  1DD6 A;  2YNV B;  3PG4 A;  3AF5 A;  5LM6 A;  4JO0 A;  1SML A;  1A8T A;  3PY5 A;  2I7X A;  2NXA A;  3IOF A;  4C1G A;  2R2D A;  5LE1 A;  2BG7 A;  5AXO A;  2NYP A;  2YCB A;  3TP9 A;  2HB9 A;  5LCF A;  5EV8 A;  2BFK A;  5IQK A;  1QH3 A;  2E7Y A;  2OHH A;  4EXS A;  2FHX B;  3VQZ A;  4CHL A;  4C1H A;  5EVD A;  5ACT A;  5LCH A;  5ACQ A;  4FR7 A;  3I0V A;  5KIK A;  4Z5Z A;  4UWR B;  1KR3 A;  5DPX A;  3ADR A;  5ACP A;  3A4Y A;  1XTO A;  2M5C A;  3KNR A;  4Z5Y A;  3IE0 A;  5AXR A;  5A0T A;  1X8I A;  4BZ3 A;  3T3N A;  2UYX A;  3F9O A;  2P18 A;  4B87 A;  4UWO B;  4XUK A;  3IEL A;  2GFJ A;  1ZTC A;  5K4K A;  4YSK A;  4C1D A;  2WYM C;  3IEM A;  4UBQ A;  2YNW A;  3X2Y A;  2P4Z A;  3ESH A;  3ZWF A;  4XWW A;  4NQ5 A;  4KEQ A;  2FK6 A;  3X30 A;  2WYL A;  3DHA A;  3IE1 A;  4EYF A;  5ACU A;  1BC2 A;  3Q6V A;  3ZQ4 A;  4O98 A;  4AD9 A;  2NZF A;  3SPU A;  5B1U A;  1WUP A;  3KL7 A;  4RBS A;  5EVB A;  1JT1 A;  5B3R A;  4GYU A;  1VJN A;  2AZ4 A;  2BIB A;  3BK1 A;  4UWP B;  3T3O A;  5EW0 A;  1YCG A;  4NQ6 A;  4J5F A;  2YNT A;  1P9E A;  1WRA A;  1YCH A;  5K4M A;  2BGA A;  4ZO3 A;  3IE2 A;  4P62 A;  4NQ4 A;  1WUO A;  2Y8B A;  2BR6 A;  3RPC A;  2XF4 A;  3H3E A;  5EVK A;  3QH8 A;  2BFZ B;  4D1V A;  2BFZ A;  1ZKP A;  1BVT A;  4H0D A;  2OHI A;  5K4N A;  2FHX A;  4EFZ A;  4HL1 A;  3G1P A;  4Z60 A;  1XM8 A;  4DIK A;  3FAI A;  3MD7 A;  2OHJ A;  4UA4 A;  4BP0 A;  3T9M A;  5EH9 A;  2FU8 A;  2I7V A;  2BFL A;  3S0Z A;  2DKF A;  5FQA A;  2WYM A;  4GCW A;  4TZF A;  1DXK A;  3I13 A;  2QDT A;  4ZEJ A;  1VME A;  3JXP A;  2Y8A A;  2YNU A;  3VPE A;  5ACX A;  1HLK A;  2BG6 A;  5LCA A;  2AIO A;  1YCF A;  3X2Z A;  4RL2 A;  3SFP A;  3AJ3 A;  3FCZ A;  2BC2 A;  4DIL A;  4RAW A;  1KO3 A;  4XWT A;  2FU7 A;  2ZZI A;  5EWA A;  5HH5 A;  3KNS A;  5AHO A;  4F6Z A;  2FM6 A;  4KEP A;  1A7T A;  4V0H A;  4PVO A;  4C1E A;  3DHC A;  5ACV A;  4Z67 A;  3L6N A;  4EYL A;  4C1C A;  4TZB A;  2BMI A;  4D1W A;  1M2X A;  3P2U A;  1VGN A;  4TZ9 A;  3SW3 A;  1DDK A;  4TYF A;  3SD9 A;  2ZWR A;  4AWY B;  2QIN A;  5HIP A;  1JJT A;  2Q42 A;  3BC2 A;  2H6A A;  2YNT B;  2CBN A;  5AHR A;  3SBL A;  2GFK A;  3DH8 A;  4TZE A;  1ZNB A;  3IEK A;  3PY6 A;  2FU9 A;  4WD6 A;  4D1T A;  1E5D A;  1K07 A;  3WXC A;  2P97 A;  4J5H A;  2WRS A;  2YNV A;  4AX0 B;  3IDZ A;  2GMN A;  3ZNB A;  2P1E A;  5LLD A;  5EHT A;  2BG8 A;  1KO2 A;  4D1U A;  2Y87 A;  4ZO2 A; 
#chains in the Genus database with same CATH topology
 5LS3 A;  4EY2 A;  3AF6 A;  5A0V A;  1WW1 A;  4RL0 A;  2A7M A;  3X2X A;  1X8G A;  2QDS A;  5HIS A;  2NZE A;  5HIO A;  4NQ2 A;  3I11 A;  2CG3 A;  5A87 A;  1MQO A;  5A5Z A;  2FU6 A;  4RAM A;  1X8H A;  2BTN A;  3DHB A;  4C1F A;  1BMC A;  4F6H A;  3R2U A;  4FEK A;  4Z7R A;  1JJE A;  2QJS A;  5ACW A;  4RM5 A;  4C09 A;  2ZNB A;  4PVT A;  4UWS B;  5HIQ A;  3IOG A;  5ACR A;  4HL2 A;  5LSC A;  2YZ3 A;  4LE6 A;  5KIL A;  3RKJ A;  3ZR9 A;  2WHG A;  4YSB A;  4AWZ A;  3BV6 A;  5AEB A;  5AYA A;  4TYT A;  3I14 A;  3I15 A;  4U4L A;  4EYB A;  4HKY A;  5HH6 A;  2BG8 B;  4Z6X A;  3RKK A;  2GCU A;  2XR1 A;  3LVZ A;  3BK2 A;  4UAM A;  4ZNB A;  5LMC A;  1Y44 A;  2I7T A;  4FSB A;  4EXY A;  5ACS A;  2DOO A;  4AX1 B;  5B15 A;  2Q0I A;  5HH4 A;  5FQC A;  5K0W A;  5A23 A;  2VW8 A;  3SRX A;  2ZO4 A;  4D02 A;  1L9Y A;  2Q9U A;  2GKL A;  1QH5 A;  2Q0J A;  2QED A;  2M5D A;  4GYQ A;  2BG2 A;  5EV6 A;  5FQB A;  4YSL A;  1DD6 A;  2YNV B;  3PG4 A;  3AF5 A;  5LM6 A;  4JO0 A;  1SML A;  1A8T A;  3PY5 A;  2I7X A;  2NXA A;  3IOF A;  4C1G A;  2R2D A;  5LE1 A;  2BG7 A;  5AXO A;  2NYP A;  2YCB A;  3TP9 A;  2HB9 A;  5LCF A;  5EV8 A;  2BFK A;  5IQK A;  1QH3 A;  2E7Y A;  2OHH A;  4EXS A;  2FHX B;  3VQZ A;  4CHL A;  4C1H A;  5EVD A;  5ACT A;  5LCH A;  5ACQ A;  4FR7 A;  3I0V A;  5KIK A;  4Z5Z A;  5AJL A;  4UWR B;  1KR3 A;  5DPX A;  3ADR A;  5ACP A;  3A4Y A;  1XTO A;  2M5C A;  3KNR A;  4Z5Y A;  3IE0 A;  5AXR A;  5A0T A;  1X8I A;  4BZ3 A;  3T3N A;  2UYX A;  3F9O A;  2P18 A;  2CFU A;  4B87 A;  4UWO B;  4XUK A;  3IEL A;  2GFJ A;  1ZTC A;  5K4K A;  4YSK A;  4C1D A;  2WYM C;  3IEM A;  4UBQ A;  2YNW A;  3X2Y A;  2P4Z A;  3ESH A;  3ZWF A;  4XWW A;  4NQ5 A;  4KEQ A;  2FK6 A;  3X30 A;  2WYL A;  3DHA A;  3IE1 A;  4EYF A;  5ACU A;  1BC2 A;  3Q6V A;  3ZQ4 A;  4O98 A;  4AD9 A;  2NZF A;  3SPU A;  5B1U A;  1WUP A;  3KL7 A;  4RBS A;  5EVB A;  1JT1 A;  5B3R A;  4GYU A;  1VJN A;  2AZ4 A;  2BIB A;  3BK1 A;  4UWP B;  4AV7 A;  3T3O A;  5EW0 A;  1YCG A;  4NQ6 A;  4J5F A;  2YNT A;  1P9E A;  1WRA A;  1YCH A;  5K4M A;  2BGA A;  4ZO3 A;  3IE2 A;  4P62 A;  4NQ4 A;  1WUO A;  2Y8B A;  2BR6 A;  3RPC A;  2XF4 A;  3H3E A;  5EVK A;  3QH8 A;  2BFZ B;  4D1V A;  4PDX A;  2BFZ A;  1ZKP A;  1BVT A;  4H0D A;  2OHI A;  5K4N A;  2FHX A;  4EFZ A;  4HL1 A;  3G1P A;  4Z60 A;  1XM8 A;  4DIK A;  3FAI A;  3MD7 A;  2OHJ A;  4UA4 A;  4BP0 A;  3T9M A;  5EH9 A;  2FU8 A;  2I7V A;  2BFL A;  3S0Z A;  2DKF A;  5FQA A;  2WYM A;  4GCW A;  4TZF A;  1DXK A;  3I13 A;  2QDT A;  4ZEJ A;  1VME A;  3JXP A;  2Y8A A;  4AXH A;  2YNU A;  3VPE A;  2CFZ A;  5ACX A;  1HLK A;  2BG6 A;  5LCA A;  2AIO A;  1YCF A;  3X2Z A;  4RL2 A;  3SFP A;  3AJ3 A;  3FCZ A;  2BC2 A;  4DIL A;  4RAW A;  1KO3 A;  4XWT A;  2FU7 A;  2ZZI A;  5EWA A;  5HH5 A;  3KNS A;  5AHO A;  4F6Z A;  5AIJ A;  2FM6 A;  4KEP A;  1A7T A;  4V0H A;  4PVO A;  4C1E A;  3DHC A;  5ACV A;  4Z67 A;  3L6N A;  4EYL A;  4C1C A;  4TZB A;  2CG2 A;  2BMI A;  4D1W A;  1M2X A;  3P2U A;  1VGN A;  4TZ9 A;  2YHE A;  3SW3 A;  1DDK A;  4TYF A;  3SD9 A;  2ZWR A;  4AWY B;  2QIN A;  5HIP A;  1JJT A;  2Q42 A;  3BC2 A;  2H6A A;  2YNT B;  2CBN A;  5AHR A;  3SBL A;  2GFK A;  3DH8 A;  4TZE A;  1ZNB A;  3IEK A;  3PY6 A;  2FU9 A;  4WD6 A;  4D1T A;  1E5D A;  1K07 A;  3WXC A;  2P97 A;  4J5H A;  2WRS A;  2YNV A;  4AX0 B;  3IDZ A;  2GMN A;  3ZNB A;  2P1E A;  5LLD A;  5EHT A;  2BG8 A;  1KO2 A;  4D1U A;  4NUR A;  2Y87 A;  4ZO2 A; 
#chains in the Genus database with same CATH homology
 5LS3 A;  4EY2 A;  3AF6 A;  5A0V A;  1WW1 A;  4RL0 A;  2A7M A;  3X2X A;  1X8G A;  2QDS A;  5HIS A;  2NZE A;  5HIO A;  4NQ2 A;  3I11 A;  5A87 A;  1MQO A;  5A5Z A;  2FU6 A;  4RAM A;  1X8H A;  2BTN A;  3DHB A;  4C1F A;  1BMC A;  4F6H A;  3R2U A;  4FEK A;  4Z7R A;  1JJE A;  2QJS A;  5ACW A;  4RM5 A;  4C09 A;  2ZNB A;  4PVT A;  4UWS B;  5HIQ A;  3IOG A;  5ACR A;  4HL2 A;  5LSC A;  2YZ3 A;  4LE6 A;  5KIL A;  3RKJ A;  3ZR9 A;  2WHG A;  4YSB A;  4AWZ A;  3BV6 A;  5AEB A;  5AYA A;  4TYT A;  3I14 A;  3I15 A;  4U4L A;  4EYB A;  4HKY A;  5HH6 A;  2BG8 B;  4Z6X A;  3RKK A;  2GCU A;  2XR1 A;  3LVZ A;  3BK2 A;  4UAM A;  4ZNB A;  5LMC A;  1Y44 A;  2I7T A;  4FSB A;  4EXY A;  5ACS A;  2DOO A;  4AX1 B;  5B15 A;  2Q0I A;  5HH4 A;  5FQC A;  5K0W A;  2VW8 A;  3SRX A;  2ZO4 A;  4D02 A;  1L9Y A;  2Q9U A;  2GKL A;  1QH5 A;  2Q0J A;  2QED A;  2M5D A;  4GYQ A;  2BG2 A;  5EV6 A;  5FQB A;  4YSL A;  1DD6 A;  2YNV B;  3PG4 A;  3AF5 A;  5LM6 A;  4JO0 A;  1SML A;  1A8T A;  3PY5 A;  2I7X A;  2NXA A;  3IOF A;  4C1G A;  2R2D A;  5LE1 A;  2BG7 A;  5AXO A;  2NYP A;  2YCB A;  3TP9 A;  2HB9 A;  5LCF A;  5EV8 A;  2BFK A;  5IQK A;  1QH3 A;  2E7Y A;  2OHH A;  4EXS A;  2FHX B;  3VQZ A;  4CHL A;  4C1H A;  5EVD A;  5ACT A;  5LCH A;  5ACQ A;  4FR7 A;  3I0V A;  5KIK A;  4Z5Z A;  4UWR B;  1KR3 A;  5DPX A;  3ADR A;  5ACP A;  3A4Y A;  1XTO A;  2M5C A;  3KNR A;  4Z5Y A;  3IE0 A;  5AXR A;  5A0T A;  1X8I A;  4BZ3 A;  3T3N A;  2UYX A;  3F9O A;  2P18 A;  4B87 A;  4UWO B;  4XUK A;  3IEL A;  2GFJ A;  1ZTC A;  5K4K A;  4YSK A;  4C1D A;  2WYM C;  3IEM A;  4UBQ A;  2YNW A;  3X2Y A;  2P4Z A;  3ESH A;  3ZWF A;  4XWW A;  4NQ5 A;  4KEQ A;  2FK6 A;  3X30 A;  2WYL A;  3DHA A;  3IE1 A;  4EYF A;  5ACU A;  1BC2 A;  3Q6V A;  3ZQ4 A;  4O98 A;  4AD9 A;  2NZF A;  3SPU A;  5B1U A;  1WUP A;  3KL7 A;  4RBS A;  5EVB A;  1JT1 A;  5B3R A;  4GYU A;  1VJN A;  2AZ4 A;  2BIB A;  3BK1 A;  4UWP B;  3T3O A;  5EW0 A;  1YCG A;  4NQ6 A;  4J5F A;  2YNT A;  1P9E A;  1WRA A;  1YCH A;  5K4M A;  2BGA A;  4ZO3 A;  3IE2 A;  4P62 A;  4NQ4 A;  1WUO A;  2Y8B A;  2BR6 A;  3RPC A;  2XF4 A;  3H3E A;  5EVK A;  3QH8 A;  2BFZ B;  4D1V A;  2BFZ A;  1ZKP A;  1BVT A;  4H0D A;  2OHI A;  5K4N A;  2FHX A;  4EFZ A;  4HL1 A;  3G1P A;  4Z60 A;  1XM8 A;  4DIK A;  3FAI A;  3MD7 A;  2OHJ A;  4UA4 A;  4BP0 A;  3T9M A;  5EH9 A;  2FU8 A;  2I7V A;  2BFL A;  3S0Z A;  2DKF A;  5FQA A;  2WYM A;  4GCW A;  4TZF A;  1DXK A;  3I13 A;  2QDT A;  4ZEJ A;  1VME A;  3JXP A;  2Y8A A;  2YNU A;  3VPE A;  5ACX A;  1HLK A;  2BG6 A;  5LCA A;  2AIO A;  1YCF A;  3X2Z A;  4RL2 A;  3SFP A;  3AJ3 A;  3FCZ A;  2BC2 A;  4DIL A;  4RAW A;  1KO3 A;  4XWT A;  2FU7 A;  2ZZI A;  5EWA A;  5HH5 A;  3KNS A;  5AHO A;  4F6Z A;  2FM6 A;  4KEP A;  1A7T A;  4V0H A;  4PVO A;  4C1E A;  3DHC A;  5ACV A;  4Z67 A;  3L6N A;  4EYL A;  4C1C A;  4TZB A;  2BMI A;  4D1W A;  1M2X A;  3P2U A;  1VGN A;  4TZ9 A;  3SW3 A;  1DDK A;  4TYF A;  3SD9 A;  2ZWR A;  4AWY B;  2QIN A;  5HIP A;  1JJT A;  2Q42 A;  3BC2 A;  2H6A A;  2YNT B;  2CBN A;  5AHR A;  3SBL A;  2GFK A;  3DH8 A;  4TZE A;  1ZNB A;  3IEK A;  3PY6 A;  2FU9 A;  4WD6 A;  4D1T A;  1E5D A;  1K07 A;  3WXC A;  2P97 A;  4J5H A;  2WRS A;  2YNV A;  4AX0 B;  3IDZ A;  2GMN A;  3ZNB A;  2P1E A;  5LLD A;  5EHT A;  2BG8 A;  1KO2 A;  4D1U A;  2Y87 A;  4ZO2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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