5ADXK

Cryoem structure of dynactin complex at 4.0 angstrom resolution
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
b'RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ACTIN RELATED PROTEIN 1
publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Structural protein
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5adxK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5adxK02
1IZNB 3AA0B 3AA1A 1IZNA 3AA0A 5ADXL 4AKRB 2KZ7B 5AFUK 4AKRA 2KZ7A 3LK41 3AA6B 3LK2B 3LK42 3LK2A 3AA6A 3AA7B 3AAAB 5ADXK 3AAAA 3AA7A 2KXPB 3LK3B 5AFUL 3AAEB 2KXPA 3AAEA 3LK3A 3AA1B
chains in the Genus database with same CATH superfamily
4GCSA 3DWOX 8PRNA 3TZGA 4AFKA 4XNKA 5FVNA 4IL6O 2KZ7A 4RJWA 3C1LA 5GTHO 3LVYA 1OSMA 4F4BA 3SZDA 5AFUL 3VZWX 3PGUA 2WJQA 1HXXA 1GFPA 4CTDA 2R89A 2XE2A 2KZ7B 2MHLA 6PRNA 1BXWA 2X9KA 2CWQA 5AFUK 2R4PA 5IYUA 3LK2B 4FUVA 2PRNA 1GFQA 3VE1A 1LW1A 3AAAA 3A0HO 3VZTX 5DL7A 4RLCA 3V8UA 4KR4A 4AKMA 3HOEA 3SZVA 4GCQA 3PQSA 2R4LA 3D7IA 4C4VB 4D65A 2JMMA 4N59A 5KAFO 4BUMX 2W81C 3A0BO 4FESA 7PRNA 4K3BA 2AXTO 4UB6O 3DA3A 3AA0B 4FRTA 4QQ1A 4D5UA 3EMNX 3RBHA 4O3XB 3POQA 3T24A 2N2MA 1E54A 4AUIA 3BS0A 4O49A 3BRZA 4PUXA 3DA4A 2F1CX 3WU2O 4RLBA 2XE5A 1QJPA 2GMYA 5G38A 2PORA 1GFMA 2M07A 2R88A 2ODJA 4FT6A 4PR7A 3VY9X 1YS5A 1KNCA 2PFXA 1BH3A 2Q0TA 1GFOA 1IZNA 2R8AA 3UAQA 2LFUA 3NJTA 3UU2A 3A2SX 5TISO 5PRNA 5G26A 3C5OA 4LSIA 2QTKA 3AA7A 4N75A 4O3WA 1IZNB 1THQA 3VY8X 4FSPA 4O4XA 2N2LA 1ZHZA 4FMSA 4O3YA 2K0LA 1ZHTA 2GE4A 3LK42 3SY7A 2OUWA 5DL8A 2XTQA 3AA6A 3AA7B 4U9CA 3HOLA 3PF1A 3LK3A 3JTYA 5DIKA 1OPFA 1HXTA 3PGRA 3GP6A 3DWNA 3AA6B 2ZLDA 4PJ0O 3UPGA 1QJ9A 3AAAB 5GTIO 2R4NA 3T0SA 3LK3B 2PRRA 3AAEA 2F1TA 4JFBA 3SYBA 5ADXL 3PORA 4LSHA 3PRNA 1P4TA 5B5EO 4AYID 4KR8A 1Q9FA 5D5DA 5ADXK 3BEYA 2XE3A 1ZHYA 3WI4A 4KRAA 4AZLA 2XG6A 2Y7SA 4FOZA 3VZUX 2IWWA 3POXA 5H2FO 2JQYA 1S5LO 3O0EA 1ME5A 1G90A 5KAIO 5DL5A 1GFNA 3BRYA 3QRCA 2KXPA 3SYSA 1VKEA 2LHFA 4FZLA 2ES9A 2XMXA 5T5FA 4G9QA 1ORMA 2R4OA 4LSEA 4AYDC 1ZHXA 2F1VA 5E79O 3KVDD 5DIPA 4GHBA 1H6S1 1ZHWA 3QRAA 4FRXA 3AA1A 3JCUO 2IJCA 4O3ZA 1HXUA 2OYOA 2OMFA 1PHOA 4K3CA 5JDPA 3LK2A 4AYNA 1MM4A 5B66O 1GU9A 4D64A 1Q9GA 3T20A 4C69X 2IWVA 4FQEA 2XTRA 3AA1B 4FSOA 3PGSA 2AF7A 2KC0A 5G3AA 2K4TA 4AKRA 2WVPA 4FZNA 2WJRA 4E1SA 4JCHA 5G39A 4C4VA 2KDYA 4AYEC 1MM5A 4GCPA 2Y2XA 3KZIO 4AYMC 5GV0A 3DZMA 3AA0A 1QJ8A 2Y0HA 4AKRB 3HWBA 2ZFGA 1MPFA 4N58A 2Y0KA 4RJXA 4UB8O 4G75A 4C00A 2ERVA 2FGRA 3AAEB 4G76A 2O4DA 2YPVA 2J1NA 1PRNA 4E1TA 5DL6A 1T1LA 2FGQX 4RL9A 3VE2A 2O4VA 3K19A 2W80C 4GF4A 2XE1A 4O4UA 1T16A 5EE2A 4FZMA 3FYXA 2J4UP 4N74A 2Y0LA 4LSFA 3PQUA 3NSGA 4Z3TA 2QEUA 4XNLA 2YNKA 2M06A 3LK41 2X27X 1BT9A 2MNHA 3G7GA 3SY9A 3POUA 2KXPB 3HW9A 2JN8A 3WI5A 1P8CA 4B61A
chains in the Genus database with same CATH topology
4FSOA 4JFBA 4GCSA 2AF7A 4RLBA 2XE5A 1QJPA 2GMYA 2KC0A 3SYBA 5ADXL 8PRNA 3TZGA 4AFKA 3PORA 4LSHA 2PORA 3PRNA 4XNKA 1GFMA 2K4TA 4AKRA 5FVNA 2M07A 2KZ7A 4RJWA 4B61A 3C1LA 4FZNA 1P4TA 2ODJA 4E1SA 4FT6A 4JCHA 3LVYA 2F1TA 1OSMA 3VY9X 4F4BA 2KDYA 1YS5A 4AYID 4KR8A 1Q9FA 5D5DA 5ADXK 4AYEC 3SZDA 3BEYA 2XE3A 1ZHYA 1MM5A 4GCPA 3VZWX 3WI4A 5AFUL 1KNCA 2PFXA 1BH3A 2Y2XA 4KRAA 4AYMC 5GV0A 2Q0TA 4AZLA 2XG6A 1HXXA 1GFOA 2Y7SA 1GFPA 1IZNA 3AA0A 1QJ8A 4FOZA 2Y0HA 2XE2A 3VZUX 4AKRB 2KZ7B 3HWBA 2MHLA 3UAQA 2LFUA 6PRNA 2ZFGA 1BXWA 3UU2A 2CWQA 5AFUK 3A2SX 1MPFA 4N58A 3POXA 5PRNA 5IYUA 3LK2B 5G26A 2Y0KA 3O0EA 4FUVA 4RJXA 4G75A 1ME5A 1G90A 2PRNA 3C5OA 1GFQA 4LSIA 3VE1A 1LW1A 2QTKA 3AAAA 5DL5A 2ERVA 3AA7A 2FGRA 1GFNA 3AAEB 3QRCA 4G76A 4O3WA 2KXPA 2O4DA 3SYSA 3VZTX 1VKEA 2LHFA 5DL7A 2YPVA 1IZNB 4FZLA 2ES9A 2J1NA 2XMXA 1THQA 5T5FA 4RLCA 3VY8X 4FSPA 4O4XA 4KR4A 3V8UA 2N2LA 1PRNA 4E1TA 5EE2A 5DL6A 4G9QA 1ZHZA 3HOEA 4AKMA 3SZVA 1ORMA 4GCQA 3PQSA 4FMSA 2FGQX 4O3YA 2J4UP 2K0LA 1ZHTA 3D7IA 4LSEA 4AYDC 1ZHXA 4RL9A 2GE4A 3LK42 3SY7A 2OUWA 2JMMA 3VE2A 5DL8A 2F1VA 4D65A 2XTQA 2O4VA 3AA6A 3AA7B 4N59A 3K19A 4BUMX 2W81C 2W80C 3KVDD 5DIPA 4GF4A 4U9CA 2XE1A 3HOLA 4FESA 4GHBA 4O4UA 3LK3A 7PRNA 3JTYA 5DIKA 1H6S1 1ZHWA 3DA3A 1OPFA 3QRAA 3FYXA 3AA0B 4FRXA 1HXTA 2Y0LA 4FRTA 4FZMA 4LSFA 3AA1A 4QQ1A 3EMNX 3PQUA 4D5UA 3RBHA 3NSGA 2IJCA 4Z3TA 2QEUA 4O3ZA 1HXUA 2OYOA 2OMFA 4XNLA 2YNKA 3GP6A 4O3XB 3POQA 3T24A 2M06A 1PHOA 3LK41 2N2MA 3AA6B 2ZLDA 1E54A 5JDPA 3LK2A 1QJ9A 4AYNA 3UPGA 1MM4A 1BT9A 2MNHA 2X27X 3AAAB 3G7GA 1GU9A 3SY9A 3POUA 4D64A 3T0SA 4AUIA 2KXPB 3LK3B 1Q9GA 3HW9A 3T20A 4O49A 4C69X 2JN8A 4PUXA 3WI5A 2PRRA 3DA4A 3AAEA 2XTRA 1P8CA 3AA1B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IZN B;  3AA0 B;  3AA1 A;  1IZN A;  3AA0 A;  5ADX L;  4AKR B;  2KZ7 B;  5AFU K;  4AKR A;  2KZ7 A;  3LK4 1;  3AA6 B;  3LK2 B;  3LK4 2;  3LK2 A;  3AA6 A;  3AA7 B;  3AAA B;  5ADX K;  3AAA A;  3AA7 A;  2KXP B;  3LK3 B;  5AFU L;  3AAE B;  2KXP A;  3AAE A;  3LK3 A;  3AA1 B; 
#chains in the Genus database with same CATH topology
 4GCS A;  3DWO X;  8PRN A;  3TZG A;  4AFK A;  4XNK A;  5FVN A;  4IL6 O;  2KZ7 A;  4RJW A;  3C1L A;  5GTH O;  3LVY A;  1OSM A;  4F4B A;  3SZD A;  5AFU L;  3VZW X;  3PGU A;  2WJQ A;  1HXX A;  1GFP A;  4CTD A;  2R89 A;  2XE2 A;  2KZ7 B;  2MHL A;  6PRN A;  1BXW A;  2X9K A;  2CWQ A;  5AFU K;  2R4P A;  5IYU A;  3LK2 B;  4FUV A;  2PRN A;  1GFQ A;  3VE1 A;  1LW1 A;  3AAA A;  3A0H O;  3VZT X;  5DL7 A;  4RLC A;  3V8U A;  4KR4 A;  4AKM A;  3HOE A;  3SZV A;  4GCQ A;  3PQS A;  2R4L A;  3D7I A;  4C4V B;  4D65 A;  2JMM A;  4N59 A;  5KAF O;  4BUM X;  2W81 C;  3A0B O;  4FES A;  7PRN A;  4K3B A;  2AXT O;  4UB6 O;  3DA3 A;  3AA0 B;  4FRT A;  4QQ1 A;  4D5U A;  3EMN X;  3RBH A;  4O3X B;  3POQ A;  3T24 A;  2N2M A;  1E54 A;  4AUI A;  3BS0 A;  4O49 A;  3BRZ A;  4PUX A;  3DA4 A;  2F1C X;  3WU2 O;  4RLB A;  2XE5 A;  1QJP A;  2GMY A;  5G38 A;  2POR A;  1GFM A;  2M07 A;  2R88 A;  2ODJ A;  4FT6 A;  4PR7 A;  3VY9 X;  1YS5 A;  1KNC A;  2PFX A;  1BH3 A;  2Q0T A;  1GFO A;  1IZN A;  2R8A A;  3UAQ A;  2LFU A;  3NJT A;  3UU2 A;  3A2S X;  5TIS O;  5PRN A;  5G26 A;  3C5O A;  4LSI A;  2QTK A;  3AA7 A;  4N75 A;  4O3W A;  1IZN B;  1THQ A;  3VY8 X;  4FSP A;  4O4X A;  2N2L A;  1ZHZ A;  4FMS A;  4O3Y A;  2K0L A;  1ZHT A;  2GE4 A;  3LK4 2;  3SY7 A;  2OUW A;  5DL8 A;  2XTQ A;  3AA6 A;  3AA7 B;  4U9C A;  3HOL A;  3PF1 A;  3LK3 A;  3JTY A;  5DIK A;  1OPF A;  1HXT A;  3PGR A;  3GP6 A;  3DWN A;  3AA6 B;  2ZLD A;  4PJ0 O;  3UPG A;  1QJ9 A;  3AAA B;  5GTI O;  2R4N A;  3T0S A;  3LK3 B;  2PRR A;  3AAE A;  2F1T A;  4JFB A;  3SYB A;  5ADX L;  3POR A;  4LSH A;  3PRN A;  1P4T A;  5B5E O;  4AYI D;  4KR8 A;  1Q9F A;  5D5D A;  5ADX K;  3BEY A;  2XE3 A;  1ZHY A;  3WI4 A;  4KRA A;  4AZL A;  2XG6 A;  2Y7S A;  4FOZ A;  3VZU X;  2IWW A;  3POX A;  5H2F O;  2JQY A;  1S5L O;  3O0E A;  1ME5 A;  1G90 A;  5KAI O;  5DL5 A;  1GFN A;  3BRY A;  3QRC A;  2KXP A;  3SYS A;  1VKE A;  2LHF A;  4FZL A;  2ES9 A;  2XMX A;  5T5F A;  4G9Q A;  1ORM A;  2R4O A;  4LSE A;  4AYD C;  1ZHX A;  2F1V A;  5E79 O;  3KVD D;  5DIP A;  4GHB A;  1H6S 1;  1ZHW A;  3QRA A;  4FRX A;  3AA1 A;  3JCU O;  2IJC A;  4O3Z A;  1HXU A;  2OYO A;  2OMF A;  1PHO A;  4K3C A;  5JDP A;  3LK2 A;  4AYN A;  1MM4 A;  5B66 O;  1GU9 A;  4D64 A;  1Q9G A;  3T20 A;  4C69 X;  2IWV A;  4FQE A;  2XTR A;  3AA1 B;  4FSO A;  3PGS A;  2AF7 A;  2KC0 A;  5G3A A;  2K4T A;  4AKR A;  2WVP A;  4FZN A;  2WJR A;  4E1S A;  4JCH A;  5G39 A;  4C4V A;  2KDY A;  4AYE C;  1MM5 A;  4GCP A;  2Y2X A;  3KZI O;  4AYM C;  5GV0 A;  3DZM A;  3AA0 A;  1QJ8 A;  2Y0H A;  4AKR B;  3HWB A;  2ZFG A;  1MPF A;  4N58 A;  2Y0K A;  4RJX A;  4UB8 O;  4G75 A;  4C00 A;  2ERV A;  2FGR A;  3AAE B;  4G76 A;  2O4D A;  2YPV A;  2J1N A;  1PRN A;  4E1T A;  5DL6 A;  1T1L A;  2FGQ X;  4RL9 A;  3VE2 A;  2O4V A;  3K19 A;  2W80 C;  4GF4 A;  2XE1 A;  4O4U A;  1T16 A;  5EE2 A;  4FZM A;  3FYX A;  2J4U P;  4N74 A;  2Y0L A;  4LSF A;  3PQU A;  3NSG A;  4Z3T A;  2QEU A;  4XNL A;  2YNK A;  2M06 A;  3LK4 1;  2X27 X;  1BT9 A;  2MNH A;  3G7G A;  3SY9 A;  3POU A;  2KXP B;  3HW9 A;  2JN8 A;  3WI5 A;  1P8C A;  4B61 A; 
#chains in the Genus database with same CATH homology
 4FSO A;  4JFB A;  4GCS A;  2AF7 A;  4RLB A;  2XE5 A;  1QJP A;  2GMY A;  2KC0 A;  3SYB A;  5ADX L;  8PRN A;  3TZG A;  4AFK A;  3POR A;  4LSH A;  2POR A;  3PRN A;  4XNK A;  1GFM A;  2K4T A;  4AKR A;  5FVN A;  2M07 A;  2KZ7 A;  4RJW A;  4B61 A;  3C1L A;  4FZN A;  1P4T A;  2ODJ A;  4E1S A;  4FT6 A;  4JCH A;  3LVY A;  2F1T A;  1OSM A;  3VY9 X;  4F4B A;  2KDY A;  1YS5 A;  4AYI D;  4KR8 A;  1Q9F A;  5D5D A;  5ADX K;  4AYE C;  3SZD A;  3BEY A;  2XE3 A;  1ZHY A;  1MM5 A;  4GCP A;  3VZW X;  3WI4 A;  5AFU L;  1KNC A;  2PFX A;  1BH3 A;  2Y2X A;  4KRA A;  4AYM C;  5GV0 A;  2Q0T A;  4AZL A;  2XG6 A;  1HXX A;  1GFO A;  2Y7S A;  1GFP A;  1IZN A;  3AA0 A;  1QJ8 A;  4FOZ A;  2Y0H A;  2XE2 A;  3VZU X;  4AKR B;  2KZ7 B;  3HWB A;  2MHL A;  3UAQ A;  2LFU A;  6PRN A;  2ZFG A;  1BXW A;  3UU2 A;  2CWQ A;  5AFU K;  3A2S X;  1MPF A;  4N58 A;  3POX A;  5PRN A;  5IYU A;  3LK2 B;  5G26 A;  2Y0K A;  3O0E A;  4FUV A;  4RJX A;  4G75 A;  1ME5 A;  1G90 A;  2PRN A;  3C5O A;  1GFQ A;  4LSI A;  3VE1 A;  1LW1 A;  2QTK A;  3AAA A;  5DL5 A;  2ERV A;  3AA7 A;  2FGR A;  1GFN A;  3AAE B;  3QRC A;  4G76 A;  4O3W A;  2KXP A;  2O4D A;  3SYS A;  3VZT X;  1VKE A;  2LHF A;  5DL7 A;  2YPV A;  1IZN B;  4FZL A;  2ES9 A;  2J1N A;  2XMX A;  1THQ A;  5T5F A;  4RLC A;  3VY8 X;  4FSP A;  4O4X A;  4KR4 A;  3V8U A;  2N2L A;  1PRN A;  4E1T A;  5EE2 A;  5DL6 A;  4G9Q A;  1ZHZ A;  3HOE A;  4AKM A;  3SZV A;  1ORM A;  4GCQ A;  3PQS A;  4FMS A;  2FGQ X;  4O3Y A;  2J4U P;  2K0L A;  1ZHT A;  3D7I A;  4LSE A;  4AYD C;  1ZHX A;  4RL9 A;  2GE4 A;  3LK4 2;  3SY7 A;  2OUW A;  2JMM A;  3VE2 A;  5DL8 A;  2F1V A;  4D65 A;  2XTQ A;  2O4V A;  3AA6 A;  3AA7 B;  4N59 A;  3K19 A;  4BUM X;  2W81 C;  2W80 C;  3KVD D;  5DIP A;  4GF4 A;  4U9C A;  2XE1 A;  3HOL A;  4FES A;  4GHB A;  4O4U A;  3LK3 A;  7PRN A;  3JTY A;  5DIK A;  1H6S 1;  1ZHW A;  3DA3 A;  1OPF A;  3QRA A;  3FYX A;  3AA0 B;  4FRX A;  1HXT A;  2Y0L A;  4FRT A;  4FZM A;  4LSF A;  3AA1 A;  4QQ1 A;  3EMN X;  3PQU A;  4D5U A;  3RBH A;  3NSG A;  2IJC A;  4Z3T A;  2QEU A;  4O3Z A;  1HXU A;  2OYO A;  2OMF A;  4XNL A;  2YNK A;  3GP6 A;  4O3X B;  3POQ A;  3T24 A;  2M06 A;  1PHO A;  3LK4 1;  2N2M A;  3AA6 B;  2ZLD A;  1E54 A;  5JDP A;  3LK2 A;  1QJ9 A;  4AYN A;  3UPG A;  1MM4 A;  1BT9 A;  2MNH A;  2X27 X;  3AAA B;  3G7G A;  1GU9 A;  3SY9 A;  3POU A;  4D64 A;  3T0S A;  4AUI A;  2KXP B;  3LK3 B;  1Q9G A;  3HW9 A;  3T20 A;  4O49 A;  4C69 X;  2JN8 A;  4PUX A;  3WI5 A;  2PRR A;  3DA4 A;  3AAE A;  2XTR A;  1P8C A;  3AA1 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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