5ADXK

Cryoem structure of dynactin complex at 4.0 angstrom resolution
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
275
structure length
275
Chain Sequence
RVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEVDGSLKSWRESCDSALRAYVKDHYSNGFCTVYAKNIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSVTVSNEAQTAKEFIKIIEHAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ACTIN RELATED PROTEIN 1
publication title The Structure of the Dynactin Complex and its Interaction with Dynein.
pubmed doi rcsb
molecule tags Structural protein
total genus 65
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2015-08-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1290.20 Mainly Alpha Up-down Bundle AhpD-like AhpD-like 5adxK01
2.40.160.80 Mainly Beta Beta Barrel Porin Porin 5adxK02
4AKRA 3AA6B 3AAEA 3AA7A 3AAAB 3LK3B 3AA1A 3LK2A 2KXPA 1IZNA 3AA0A 3AA6A 5AFUL 5AFUK 2KZ7B 3AAEB 3AAAA 3LK41 3LK3A 4AKRB 5ADXL 5ADXK 3AA7B 3AA1B 3LK42 3LK2B 2KXPB 1IZNB 3AA0B 2KZ7A
chains in the Genus database with same CATH superfamily
4FUVA 4O3ZA 4BUMX 5JDPA 5DL5A 4E1TA 4FZNA 2Y0HA 4GCSA 3VZWX 5TISO 2R4OA 5FVNA 3PGUA 3PF1A 2N2LA 4FRXA 1MM4A 3AAAB 5GTHO 2KXPA 1ZHZA 2R89A 3PQUA 1BXWA 2K4TA 1BH3A 2ZLDA 1QJ8A 1HXXA 3LK42 4O3XB 1MM5A 4AKMA 1IZNB 4GHBA 4PUXA 3UAQA 4FQEA 2AXTO 4N58A 2IWVA 1S5LO 2J1NA 1T1LA 3A2SX 4QQ1A 2KC0A 4O4XA 3POUA 2R4LA 3AAAA 2XE5A 2MNHA 2JN8A 4Z3TA 4FOZA 4C4VB 4AYNA 1ZHXA 3SY7A 2FGQX 3G7GA 1MPFA 3DA3A 5E79O 3UPGA 4RLCA 3PRNA 3WU2O 3T0SA 3WI5A 4AUIA 4FSOA 1KNCA 3AAEB 4U9CA 3HOEA 3KVDD 2AF7A 3SYSA 3A0BO 3RBHA 4AYEC 1HXTA 2Y0LA 2PFXA 3PORA 5DL8A 4C4VA 2CWQA 4RJWA 4F4BA 5G3AA 1GFPA 2QTKA 1GFMA 5IYUA 4JCHA 3SZVA 3TZGA 3SZDA 1OPFA 3VY8X 3LK41 5ADXL 3VE1A 1P8CA 1HXUA 5PRNA 4AFKA 4FESA 2WJQA 3VE2A 4IL6O 7PRNA 3HOLA 4AYDC 3AA0B 2XTQA 1T16A 2R88A 5G38A 2X9KA 2ERVA 3QRCA 2XG6A 1LW1A 2OMFA 4GCQA 5EE2A 4N75A 3BS0A 1ZHYA 3JCUO 1H6S1 3AA0A 3KZIO 4JFBA 3POXA 3NSGA 2R4PA 2XMXA 4AKRB 4B61A 2OYOA 4LSIA 2XE1A 2F1CX 3DA4A 3VZUX 3T20A 4UB6O 4C69X 5KAIO 3LK3B 2PRRA 2ODJA 2IWWA 1ZHWA 5DIPA 1ORMA 3HW9A 3SY9A 1GU9A 2KZ7B 2J4UP 2ES9A 1Q9GA 3JTYA 4N59A 3K19A 5B5EO 1P4TA 3BEYA 2R4NA 4AKRA 2O4DA 2K0LA 3PGSA 4FZLA 1PHOA 1IZNA 4O4UA 3LK3A 5GV0A 4AZLA 3AA7B 5T5FA 4D64A 3AA1B 4O3YA 2PRNA 3UU2A 1THQA 4RJXA 2KZ7A 2JQYA 4LSFA 4D65A 2GE4A 2PORA 2F1TA 1ME5A 1Q9FA 2JMMA 4N74A 5AFUL 3LVYA 3FYXA 4XNLA 1VKEA 4UB8O 2FGRA 2W80C 2WVPA 1GFQA 4FZMA 3DWOX 4GCPA 4D5UA 3AA6B 3AAEA 2Q0TA 5G26A 2LFUA 3AA7A 1PRNA 3AA1A 4PJ0O 1YS5A 2LHFA 1GFNA 3NJTA 1QJ9A 5ADXK 4G75A 4O3WA 4AYID 4FSPA 1ZHTA 3T24A 4AYMC 3VZTX 2M07A 2Y0KA 8PRNA 2QEUA 4CTDA 5H2FO 4RL9A 1G90A 3AA6A 4GF4A 2R8AA 3VY9X 2OUWA 3DZMA 4RLBA 4O49A 4G76A 3PGRA 3HWBA 2GMYA 4KR8A 3DWNA 2KDYA 3C1LA 4K3CA 2F1VA 4LSHA 3A0HO 6PRNA 4K3BA 2WJRA 3POQA 4FMSA 3D7IA 2XTRA 4PR7A 2N2MA 2Y2XA 2YPVA 4FRTA 3O0EA 5DL6A 4G9QA 5GTIO 4C00A 2Y7SA 2IJCA 2M06A 3PQSA 4KR4A 2YNKA 2MHLA 2ZFGA 2XE3A 3WI4A 2XE2A 1QJPA 3EMNX 3C5OA 3BRZA 1E54A 3LK2B 2W81C 3BRYA 5B66O 3QRAA 5G39A 2O4VA 4E1SA 5KAFO 3SYBA 5DL7A 1BT9A 1OSMA 4KRAA 4XNKA 2X27X 3V8UA 1GFOA 3LK2A 5D5DA 3GP6A 4LSEA 5AFUK 2KXPB 5DIKA 4FT6A
chains in the Genus database with same CATH topology
2PFXA 4AKRA 3PORA 5DL8A 3HWBA 2O4DA 2GMYA 2CWQA 4KR8A 4RJWA 4F4BA 4FUVA 4O3ZA 1GFPA 4BUMX 5JDPA 5DL5A 2K0LA 2KDYA 1GFMA 2QTKA 5IYUA 3C1LA 4E1TA 2F1VA 4FZLA 4LSHA 1PHOA 4JCHA 4FZNA 3SZVA 2Y0HA 1IZNA 3SZDA 4O4UA 4GCSA 1OPFA 3TZGA 6PRNA 3VY8X 3POQA 4FMSA 3D7IA 3LK41 3LK3A 2XTRA 2N2MA 2Y2XA 2YPVA 3VE1A 1P8CA 1HXUA 4FRTA 5PRNA 3VZWX 4AFKA 3AA7B 4AZLA 5GV0A 4FESA 5T5FA 4D64A 3AA1B 5FVNA 4O3YA 3O0EA 3VE2A 2PRNA 3UU2A 1THQA 3HOLA 5DL6A 4G9QA 4AYDC 4RJXA 7PRNA 3AA0B 2KZ7A 2N2LA 4LSFA 2Y7SA 2IJCA 2M06A 3PQSA 4FRXA 1MM4A 2XTQA 4D65A 2GE4A 4KR4A 3AAAB 2PORA 2F1TA 2YNKA 2MHLA 2ZFGA 2KXPA 1ZHZA 2XE3A 3WI4A 1ME5A 1Q9FA 3PQUA 2JMMA 1BXWA 2XE2A 1QJPA 5AFUL 2K4TA 3EMNX 3LVYA 1BH3A 3FYXA 4XNLA 2ZLDA 3C5OA 1QJ8A 1VKEA 2ERVA 3QRCA 1HXXA 2XG6A 2FGRA 1LW1A 2W80C 1E54A 3LK42 3LK2B 2OMFA 2W81C 4O3XB 1GFQA 1MM5A 4FZMA 1IZNB 4GCPA 4GCQA 4AKMA 4GHBA 4D5UA 4PUXA 3UAQA 3AA6B 3AAEA 2Q0TA 5EE2A 5G26A 2LFUA 3AA7A 3QRAA 4N58A 1PRNA 3AA1A 1ZHYA 2J1NA 2O4VA 4E1SA 3A2SX 4QQ1A 2KC0A 1H6S1 3AA0A 1YS5A 4O4XA 2LHFA 3POUA 1GFNA 4JFBA 3POXA 3NSGA 2XMXA 3AAAA 2XE5A 2MNHA 2JN8A 4AKRB 4Z3TA 3SYBA 1QJ9A 4FOZA 4B61A 5ADXK 5DL7A 4G75A 1BT9A 1OSMA 2OYOA 4O3WA 4AYNA 4LSIA 2XE1A 4AYID 4KRAA 3DA4A 4FSPA 1ZHXA 1ZHTA 3SY7A 3T24A 2FGQX 3VZUX 3T20A 4XNKA 3G7GA 4AYMC 5ADXL 3VZTX 2X27X 2M07A 4C69X 1MPFA 3LK3B 2PRRA 2ODJA 3DA3A 3V8UA 1GFOA 3LK2A 2Y0KA 3GP6A 5D5DA 2QEUA 1ZHWA 8PRNA 5DIPA 1ORMA 3HW9A 3UPGA 4RL9A 4LSEA 3SY9A 1G90A 1GU9A 4RLCA 3PRNA 3T0SA 3WI5A 3AA6A 4GF4A 4AUIA 5AFUK 1KNCA 2KZ7B 3AAEB 4FSOA 3HOEA 4U9CA 2J4UP 4RLBA 2ES9A 3KVDD 2AF7A 1Q9GA 3VY9X 3SYSA 3JTYA 4N59A 2OUWA 3K19A 2KXPB 1P4TA 3RBHA 3BEYA 5DIKA 4FT6A 4AYEC 1HXTA 4O49A 2Y0LA 4G76A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AKR A;  3AA6 B;  3AAE A;  3AA7 A;  3AAA B;  3LK3 B;  3AA1 A;  3LK2 A;  2KXP A;  1IZN A;  3AA0 A;  3AA6 A;  5AFU L;  5AFU K;  2KZ7 B;  3AAE B;  3AAA A;  3LK4 1;  3LK3 A;  4AKR B;  5ADX L;  5ADX K;  3AA7 B;  3AA1 B;  3LK4 2;  3LK2 B;  2KXP B;  1IZN B;  3AA0 B;  2KZ7 A; 
#chains in the Genus database with same CATH topology
 4FUV A;  4O3Z A;  4BUM X;  5JDP A;  5DL5 A;  4E1T A;  4FZN A;  2Y0H A;  4GCS A;  3VZW X;  5TIS O;  2R4O A;  5FVN A;  3PGU A;  3PF1 A;  2N2L A;  4FRX A;  1MM4 A;  3AAA B;  5GTH O;  2KXP A;  1ZHZ A;  2R89 A;  3PQU A;  1BXW A;  2K4T A;  1BH3 A;  2ZLD A;  1QJ8 A;  1HXX A;  3LK4 2;  4O3X B;  1MM5 A;  4AKM A;  1IZN B;  4GHB A;  4PUX A;  3UAQ A;  4FQE A;  2AXT O;  4N58 A;  2IWV A;  1S5L O;  2J1N A;  1T1L A;  3A2S X;  4QQ1 A;  2KC0 A;  4O4X A;  3POU A;  2R4L A;  3AAA A;  2XE5 A;  2MNH A;  2JN8 A;  4Z3T A;  4FOZ A;  4C4V B;  4AYN A;  1ZHX A;  3SY7 A;  2FGQ X;  3G7G A;  1MPF A;  3DA3 A;  5E79 O;  3UPG A;  4RLC A;  3PRN A;  3WU2 O;  3T0S A;  3WI5 A;  4AUI A;  4FSO A;  1KNC A;  3AAE B;  4U9C A;  3HOE A;  3KVD D;  2AF7 A;  3SYS A;  3A0B O;  3RBH A;  4AYE C;  1HXT A;  2Y0L A;  2PFX A;  3POR A;  5DL8 A;  4C4V A;  2CWQ A;  4RJW A;  4F4B A;  5G3A A;  1GFP A;  2QTK A;  1GFM A;  5IYU A;  4JCH A;  3SZV A;  3TZG A;  3SZD A;  1OPF A;  3VY8 X;  3LK4 1;  5ADX L;  3VE1 A;  1P8C A;  1HXU A;  5PRN A;  4AFK A;  4FES A;  2WJQ A;  3VE2 A;  4IL6 O;  7PRN A;  3HOL A;  4AYD C;  3AA0 B;  2XTQ A;  1T16 A;  2R88 A;  5G38 A;  2X9K A;  2ERV A;  3QRC A;  2XG6 A;  1LW1 A;  2OMF A;  4GCQ A;  5EE2 A;  4N75 A;  3BS0 A;  1ZHY A;  3JCU O;  1H6S 1;  3AA0 A;  3KZI O;  4JFB A;  3POX A;  3NSG A;  2R4P A;  2XMX A;  4AKR B;  4B61 A;  2OYO A;  4LSI A;  2XE1 A;  2F1C X;  3DA4 A;  3VZU X;  3T20 A;  4UB6 O;  4C69 X;  5KAI O;  3LK3 B;  2PRR A;  2ODJ A;  2IWW A;  1ZHW A;  5DIP A;  1ORM A;  3HW9 A;  3SY9 A;  1GU9 A;  2KZ7 B;  2J4U P;  2ES9 A;  1Q9G A;  3JTY A;  4N59 A;  3K19 A;  5B5E O;  1P4T A;  3BEY A;  2R4N A;  4AKR A;  2O4D A;  2K0L A;  3PGS A;  4FZL A;  1PHO A;  1IZN A;  4O4U A;  3LK3 A;  5GV0 A;  4AZL A;  3AA7 B;  5T5F A;  4D64 A;  3AA1 B;  4O3Y A;  2PRN A;  3UU2 A;  1THQ A;  4RJX A;  2KZ7 A;  2JQY A;  4LSF A;  4D65 A;  2GE4 A;  2POR A;  2F1T A;  1ME5 A;  1Q9F A;  2JMM A;  4N74 A;  5AFU L;  3LVY A;  3FYX A;  4XNL A;  1VKE A;  4UB8 O;  2FGR A;  2W80 C;  2WVP A;  1GFQ A;  4FZM A;  3DWO X;  4GCP A;  4D5U A;  3AA6 B;  3AAE A;  2Q0T A;  5G26 A;  2LFU A;  3AA7 A;  1PRN A;  3AA1 A;  4PJ0 O;  1YS5 A;  2LHF A;  1GFN A;  3NJT A;  1QJ9 A;  5ADX K;  4G75 A;  4O3W A;  4AYI D;  4FSP A;  1ZHT A;  3T24 A;  4AYM C;  3VZT X;  2M07 A;  2Y0K A;  8PRN A;  2QEU A;  4CTD A;  5H2F O;  4RL9 A;  1G90 A;  3AA6 A;  4GF4 A;  2R8A A;  3VY9 X;  2OUW A;  3DZM A;  4RLB A;  4O49 A;  4G76 A;  3PGR A;  3HWB A;  2GMY A;  4KR8 A;  3DWN A;  2KDY A;  3C1L A;  4K3C A;  2F1V A;  4LSH A;  3A0H O;  6PRN A;  4K3B A;  2WJR A;  3POQ A;  4FMS A;  3D7I A;  2XTR A;  4PR7 A;  2N2M A;  2Y2X A;  2YPV A;  4FRT A;  3O0E A;  5DL6 A;  4G9Q A;  5GTI O;  4C00 A;  2Y7S A;  2IJC A;  2M06 A;  3PQS A;  4KR4 A;  2YNK A;  2MHL A;  2ZFG A;  2XE3 A;  3WI4 A;  2XE2 A;  1QJP A;  3EMN X;  3C5O A;  3BRZ A;  1E54 A;  3LK2 B;  2W81 C;  3BRY A;  5B66 O;  3QRA A;  5G39 A;  2O4V A;  4E1S A;  5KAF O;  3SYB A;  5DL7 A;  1BT9 A;  1OSM A;  4KRA A;  4XNK A;  2X27 X;  3V8U A;  1GFO A;  3LK2 A;  5D5D A;  3GP6 A;  4LSE A;  5AFU K;  2KXP B;  5DIK A;  4FT6 A; 
#chains in the Genus database with same CATH homology
 2PFX A;  4AKR A;  3POR A;  5DL8 A;  3HWB A;  2O4D A;  2GMY A;  2CWQ A;  4KR8 A;  4RJW A;  4F4B A;  4FUV A;  4O3Z A;  1GFP A;  4BUM X;  5JDP A;  5DL5 A;  2K0L A;  2KDY A;  1GFM A;  2QTK A;  5IYU A;  3C1L A;  4E1T A;  2F1V A;  4FZL A;  4LSH A;  1PHO A;  4JCH A;  4FZN A;  3SZV A;  2Y0H A;  1IZN A;  3SZD A;  4O4U A;  4GCS A;  1OPF A;  3TZG A;  6PRN A;  3VY8 X;  3POQ A;  4FMS A;  3D7I A;  3LK4 1;  3LK3 A;  2XTR A;  2N2M A;  2Y2X A;  2YPV A;  3VE1 A;  1P8C A;  1HXU A;  4FRT A;  5PRN A;  3VZW X;  4AFK A;  3AA7 B;  4AZL A;  5GV0 A;  4FES A;  5T5F A;  4D64 A;  3AA1 B;  5FVN A;  4O3Y A;  3O0E A;  3VE2 A;  2PRN A;  3UU2 A;  1THQ A;  3HOL A;  5DL6 A;  4G9Q A;  4AYD C;  4RJX A;  7PRN A;  3AA0 B;  2KZ7 A;  2N2L A;  4LSF A;  2Y7S A;  2IJC A;  2M06 A;  3PQS A;  4FRX A;  1MM4 A;  2XTQ A;  4D65 A;  2GE4 A;  4KR4 A;  3AAA B;  2POR A;  2F1T A;  2YNK A;  2MHL A;  2ZFG A;  2KXP A;  1ZHZ A;  2XE3 A;  3WI4 A;  1ME5 A;  1Q9F A;  3PQU A;  2JMM A;  1BXW A;  2XE2 A;  1QJP A;  5AFU L;  2K4T A;  3EMN X;  3LVY A;  1BH3 A;  3FYX A;  4XNL A;  2ZLD A;  3C5O A;  1QJ8 A;  1VKE A;  2ERV A;  3QRC A;  1HXX A;  2XG6 A;  2FGR A;  1LW1 A;  2W80 C;  1E54 A;  3LK4 2;  3LK2 B;  2OMF A;  2W81 C;  4O3X B;  1GFQ A;  1MM5 A;  4FZM A;  1IZN B;  4GCP A;  4GCQ A;  4AKM A;  4GHB A;  4D5U A;  4PUX A;  3UAQ A;  3AA6 B;  3AAE A;  2Q0T A;  5EE2 A;  5G26 A;  2LFU A;  3AA7 A;  3QRA A;  4N58 A;  1PRN A;  3AA1 A;  1ZHY A;  2J1N A;  2O4V A;  4E1S A;  3A2S X;  4QQ1 A;  2KC0 A;  1H6S 1;  3AA0 A;  1YS5 A;  4O4X A;  2LHF A;  3POU A;  1GFN A;  4JFB A;  3POX A;  3NSG A;  2XMX A;  3AAA A;  2XE5 A;  2MNH A;  2JN8 A;  4AKR B;  4Z3T A;  3SYB A;  1QJ9 A;  4FOZ A;  4B61 A;  5ADX K;  5DL7 A;  4G75 A;  1BT9 A;  1OSM A;  2OYO A;  4O3W A;  4AYN A;  4LSI A;  2XE1 A;  4AYI D;  4KRA A;  3DA4 A;  4FSP A;  1ZHX A;  1ZHT A;  3SY7 A;  3T24 A;  2FGQ X;  3VZU X;  3T20 A;  4XNK A;  3G7G A;  4AYM C;  5ADX L;  3VZT X;  2X27 X;  2M07 A;  4C69 X;  1MPF A;  3LK3 B;  2PRR A;  2ODJ A;  3DA3 A;  3V8U A;  1GFO A;  3LK2 A;  2Y0K A;  3GP6 A;  5D5D A;  2QEU A;  1ZHW A;  8PRN A;  5DIP A;  1ORM A;  3HW9 A;  3UPG A;  4RL9 A;  4LSE A;  3SY9 A;  1G90 A;  1GU9 A;  4RLC A;  3PRN A;  3T0S A;  3WI5 A;  3AA6 A;  4GF4 A;  4AUI A;  5AFU K;  1KNC A;  2KZ7 B;  3AAE B;  4FSO A;  3HOE A;  4U9C A;  2J4U P;  4RLB A;  2ES9 A;  3KVD D;  2AF7 A;  1Q9G A;  3VY9 X;  3SYS A;  3JTY A;  4N59 A;  2OUW A;  3K19 A;  2KXP B;  1P4T A;  3RBH A;  3BEY A;  5DIK A;  4FT6 A;  4AYE C;  1HXT A;  4O49 A;  2Y0L A;  4G76 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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