5AELA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-597
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
367
structure length
357
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation.
pubmed doi rcsb
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE
molecule tags Transferase
source organism Trypanosoma brucei
total genus 148
structure length 357
sequence length 367
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2014-12-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5aelA00
2Z4WA 3P8RA 3LDWA 1ZW5A 1YHKA 3QKCA 2PS6A 4WK5A 4LLTA 5EAUA 2PS5A 2DH4A 4LLSA 4NFIF 2F8CF 1WMWA 5B0IA 3Q30A 3Q1OA 5DJRF 1UBXA 4KVIA 3KRAB 1N20A 5HN8A 3WCBA 3ASXA 2ZCRA 2F8ZF 3KRFA 3WJNA 1YJ4A 3CC9A 4F6VA 3WCHA 3ICZA 2Z4XA 3B7LA 3DYHA 3P5PA 2E91A 4MC8A 5ILZA 2Z7HA 3TFVA 2AETA 5JV0F 2RAHA 2FORA 3N1WF 4LTVA 5DGMF 2F94F 4Q23A 5E8LA 3WC9A 1HM4A 3ACYA 4JVJF 1VG4A 5B0MA 4N1ZF 5HNAA 1KIZA 1UBWA 3OABA 3M00A 3WCMA 2ZCOA 3WCAA 1RQJA 5IMPA 5DGSF 3ICKA 1FPSA 3KRFB 4ZQ8A 5ILJA 3LSNA 4KFAA 4HD1A 4LIXA 4FP4A 3V66A 3TFNA 1N23A 1WL0A 3SDTA 3PKOA 4OKZA 5DW7A 3LZ9A 3TFPA 3WSAA 3EFQA 4DEMF 3NPKA 4JXYA 4N9UA 3WCCA 2EWGA 3OABB 3MAVA 3OYRA 4DZWA 5IK0A 3RYEA 3IBAA 3LGKA 2F92F 4E9UA 3W7FA 3AQBB 4NFJF 5ERMA 4JZXA 1YYQA 3CKEA 5IL8A 3LVSA 3LMDA 1RTRA 4LA6A 2F7MF 3WEHA 4LXWA 4GA3A 3VJBA 5B0LA 1WL3A 4LPHF 4LA5A 1YYSA 2Z78A 4E1EA 5A0JA 1N1BA 5CG6A 2ONGA 2ZCSA 3KRPA 1V4IA 5DGNF 2E8WA 1WKZA 3SDVA 3VJCA 3SAEA 3RBMA 3WEIA 2OA6A 4P0VA 5C05A 2E94A 3G4FA 5IVGA 5ILKA 3WCLA 3M01A 2J1PA 4F6XA 4KPDA 3M02A 1YQ7A 3ACXA 3WCGA 3NPRA 4F62A 3LOMA 4QXSF 4RNQA 5DHIA 1HXGA 4FJQA 5AYPA 1WL2A 3ADZA 2E90A 2E8TA 3UCAA 4NUAA 5DJVF 1DI1A 3TC1A 5JV2F 2ONHA 3KRPB 5IMNA 3KBKA 2PS7A 3NF2A 3VJ9A 3N5JF 5AHUB 4KQSA 3WCFA 3PDEA 5KSXF 4KWDA 3BNYA 2Z4VA 1VG3A 3PYBA 5IM1A 5A0KA 3LJIA 4H5EF 5I1UA 3P5RA 4DI5A 3V1VA 1V4HA 4NKEA 1N21A 3ICNA 1EZFA 2OPMA 4KVDA 3WEFA 1WY0A 4PVXF 3P8LA 4JYXA 5IN8A 2Z50A 3N0FA 4LPGF 3DYFA 5HN7A 3KB9A 1V4KA 3EZ3A 4KQUA 4KQ5A 4LFVF 4NKFA 5DHKA 2AZJA 3S9VA 2PS8A 4KVYA 2P1CA 3G4DA 5EROA 1RQIA 2Z4YA 2ZEUA 1YYUA 4EA0A 4RXDA 2ZCQA 5IKAA 3ICMA 3OACA 4KPJA 2E93A 4P0WA 5IMIA 3WCJA 1YHLA 3ZL6A 4NG6A 2AELA 2QISA 2ZY1A 4KKMA 3WCEA 3N3DA 2E95A 3AE0A 5B03A 4E9ZA 2E8XA 4H5DF 4EA2A 3Q2ZA 5ILDA 1HX9A 5JV1F 2OGDA 4GAXA 4RXAA 4DWBA 3WCIA 3SDQA 4K10A 5HN9A 3MZVA 4OMGA 5DJPF 1YYTA 1UBVA 4PVYF 4LTZA 3OACB 4XQSF 5JUZF 3M0GA 1V4JA 1N22A 4LOBA 1N24A 5AELA 3N5HF 5B0KA 3PYAA 4NFKF 4LFGA 1VG6A 4GP2A 2Q9ZA 3KRCA 3BNXA 4H5CF 3QQVA 5CG5A 1HXCA 2OPNA 2Q58A 3V1XA 3WEGA 3WCDA 4LUUA 2J1OA 3SDRA 5IL3A 4OKMA 3WJKA 3PH7A 3DYGA 5AFXA 5H9DA 4UMJA 3ZMBA 3ZCDA 4KUXA 3IPIA 2PS4A 4JZBA 3S4JA 3EGTA 4RXCA 1VG7A 3RYWA 5IK6A 2ZEVA 1VG2A 5ILIA 5EASA 3LG5A 4DWGA 3AQ0A 5B00A 3VJDA 1N1ZA 4GP1A 5E8KA 2E8UA 3WE9A 3NRIA 3APZA 3KRCB 2O1OA 3ZMCA 1HM7A 3LLWA 4OMHA 1JFGA 1YV5A 4MC0A 2E4OA 2AEKA 3VJ8A 3WSBA 2F89F 3RMGA 4XQTF 2Z52A 5B02A 4QPFA 3ZOUA 3VJEA 4RXEA 3N46F 2J5CA 4JXNA 3N1VF 3SDUA 4LZ3A 4P0XA 2E92A 2I19A 4OGUA 3P41A 1DGPA 3KROA 3N6KF 2VF6A 5A0IA 3TS7A 1YYRA 2AZLA 3N0GA 5EATA 5B01A 5E8HA 3LK5A 3N49F 3ACWA 4MC3A 2H8OA 1UBYA 1PS1A 5ILHA 1KIYA 3Q2QA 3CP6A 1JFAA 2AZKA 2FTZA 1WL1A 3ID0A 5DZ2A 1HXAA 2Z4ZA 5ER8A 3VJAA 4LZ0A 5IKHA 2E8VA 5B0JA 3LGZB 3KROB 3LEEA 2Z7IA 4RYPA 3AQCB 4DHDA 3KRAA 5JA0F 4KK2A 5ILYA 4EA1A 4KVWA 4DXJA 3N45F 5ERNA 1YHMA 4LFEA 3WEJA 4LZCA 4L2XF 3WJOA 4XQRF 2Q80A 1V4EA 2F9KF 5DIQF 3M9UA 5IK9A 3WEKA 2Q9YA 3N3LF
chains in the Genus database with same CATH superfamily
2Z4WA 3P8RA 3LDWA 1ZW5A 1YHKA 3QKCA 2PS6A 4WK5A 4LLTA 5EAUA 2PS5A 2DH4A 4LLSA 4NFIF 2F8CF 1WMWA 5B0IA 3Q30A 3Q1OA 5DJRF 1UBXA 4KVIA 3KRAB 1N20A 5HN8A 3WCBA 3ASXA 2ZCRA 2F8ZF 3KRFA 3WJNA 1YJ4A 3CC9A 4F6VA 3WCHA 3ICZA 2Z4XA 3B7LA 3DYHA 3P5PA 2E91A 4MC8A 5ILZA 2Z7HA 3TFVA 2AETA 5JV0F 2RAHA 2FORA 3N1WF 4LTVA 5DGMF 2F94F 4Q23A 5E8LA 3WC9A 1HM4A 3ACYA 4JVJF 1VG4A 5B0MA 4N1ZF 5HNAA 1KIZA 1UBWA 3OABA 3M00A 3WCMA 2ZCOA 3WCAA 1RQJA 5IMPA 5DGSF 3ICKA 1FPSA 3KRFB 4ZQ8A 5ILJA 3LSNA 4KFAA 4HD1A 4LIXA 4FP4A 3V66A 3TFNA 1N23A 1WL0A 3SDTA 3PKOA 4OKZA 5DW7A 3LZ9A 3TFPA 3WSAA 3EFQA 4DEMF 3NPKA 4JXYA 4N9UA 3WCCA 2EWGA 3OABB 3MAVA 3OYRA 4DZWA 5IK0A 3RYEA 3IBAA 3LGKA 2F92F 4E9UA 3W7FA 3AQBB 4NFJF 5ERMA 4JZXA 1YYQA 3CKEA 5IL8A 3LVSA 3LMDA 1RTRA 4LA6A 2F7MF 3WEHA 4LXWA 4GA3A 3VJBA 5B0LA 1WL3A 4LPHF 4LA5A 1YYSA 2Z78A 4E1EA 5A0JA 1N1BA 5CG6A 2ONGA 2ZCSA 3KRPA 1V4IA 5DGNF 2E8WA 1WKZA 3SDVA 3VJCA 3SAEA 3RBMA 3WEIA 2OA6A 4P0VA 5C05A 2E94A 3G4FA 5IVGA 5ILKA 3WCLA 3M01A 2J1PA 4F6XA 4KPDA 3M02A 1YQ7A 3ACXA 3WCGA 3NPRA 4F62A 3LOMA 4QXSF 4RNQA 5DHIA 1HXGA 4FJQA 5AYPA 1WL2A 3ADZA 2E90A 2E8TA 3UCAA 4NUAA 5DJVF 1DI1A 3TC1A 5JV2F 2ONHA 3KRPB 5IMNA 3KBKA 2PS7A 3NF2A 3VJ9A 3N5JF 5AHUB 4KQSA 3WCFA 3PDEA 5KSXF 4KWDA 3BNYA 2Z4VA 1VG3A 3PYBA 5IM1A 5A0KA 3LJIA 4H5EF 5I1UA 3P5RA 4DI5A 3V1VA 1V4HA 4NKEA 1N21A 3ICNA 1EZFA 2OPMA 4KVDA 3WEFA 1WY0A 4PVXF 3P8LA 4JYXA 5IN8A 2Z50A 3N0FA 4LPGF 3DYFA 5HN7A 3KB9A 1V4KA 3EZ3A 4KQUA 4KQ5A 4LFVF 4NKFA 5DHKA 2AZJA 3S9VA 2PS8A 4KVYA 2P1CA 3G4DA 5EROA 1RQIA 2Z4YA 2ZEUA 1YYUA 4EA0A 4RXDA 2ZCQA 5IKAA 3ICMA 3OACA 4KPJA 2E93A 4P0WA 5IMIA 3WCJA 1YHLA 3ZL6A 4NG6A 2AELA 2QISA 2ZY1A 4KKMA 3WCEA 3N3DA 2E95A 3AE0A 5B03A 4E9ZA 2E8XA 4H5DF 4EA2A 3Q2ZA 5ILDA 1HX9A 5JV1F 2OGDA 4GAXA 4RXAA 4DWBA 3WCIA 3SDQA 4K10A 5HN9A 3MZVA 4OMGA 5DJPF 1YYTA 1UBVA 4PVYF 4LTZA 3OACB 4XQSF 5JUZF 3M0GA 1V4JA 1N22A 4LOBA 1N24A 5AELA 3N5HF 5B0KA 3PYAA 4NFKF 4LFGA 1VG6A 4GP2A 2Q9ZA 3KRCA 3BNXA 4H5CF 3QQVA 5CG5A 1HXCA 2OPNA 2Q58A 3V1XA 3WEGA 3WCDA 4LUUA 2J1OA 3SDRA 5IL3A 4OKMA 3WJKA 3PH7A 3DYGA 5AFXA 5H9DA 4UMJA 3ZMBA 3ZCDA 4KUXA 3IPIA 2PS4A 4JZBA 3S4JA 3EGTA 4RXCA 1VG7A 3RYWA 5IK6A 2ZEVA 1VG2A 5ILIA 5EASA 3LG5A 4DWGA 3AQ0A 5B00A 3VJDA 1N1ZA 4GP1A 5E8KA 2E8UA 3WE9A 3NRIA 3APZA 3KRCB 2O1OA 3ZMCA 1HM7A 3LLWA 4OMHA 1JFGA 1YV5A 4MC0A 2E4OA 2AEKA 3VJ8A 3WSBA 2F89F 3RMGA 4XQTF 2Z52A 5B02A 4QPFA 3ZOUA 3VJEA 4RXEA 3N46F 2J5CA 4JXNA 3N1VF 3SDUA 4LZ3A 4P0XA 2E92A 2I19A 4OGUA 3P41A 1DGPA 3KROA 3N6KF 2VF6A 5A0IA 3TS7A 1YYRA 2AZLA 3N0GA 5EATA 5B01A 5E8HA 3LK5A 3N49F 3ACWA 4MC3A 2H8OA 1UBYA 1PS1A 5ILHA 1KIYA 3Q2QA 3CP6A 1JFAA 2AZKA 2FTZA 1WL1A 3ID0A 5DZ2A 1HXAA 2Z4ZA 5ER8A 3VJAA 4LZ0A 5IKHA 2E8VA 5B0JA 3LGZB 3KROB 3LEEA 2Z7IA 4RYPA 3AQCB 4DHDA 3KRAA 5JA0F 4KK2A 5ILYA 4EA1A 4KVWA 4DXJA 3N45F 5ERNA 1YHMA 4LFEA 3WEJA 4LZCA 4L2XF 3WJOA 4XQRF 2Q80A 1V4EA 2F9KF 5DIQF 3M9UA 5IK9A 3WEKA 2Q9YA 3N3LF
chains in the Genus database with same CATH topology
2Z4WA 3P8RA 3LDWA 1ZW5A 1YHKA 3QKCA 2PS6A 4WK5A 4LLTA 5EAUA 2PS5A 2DH4A 4LLSA 4NFIF 2F8CF 1WMWA 5B0IA 3Q30A 3Q1OA 5DJRF 1UBXA 4KVIA 3KRAB 1N20A 5HN8A 3WCBA 3ASXA 2ZCRA 2F8ZF 3KRFA 3WJNA 1YJ4A 3CC9A 4F6VA 3WCHA 3ICZA 2Z4XA 3B7LA 3DYHA 3P5PA 2E91A 4MC8A 5ILZA 2Z7HA 3TFVA 2AETA 5JV0F 2RAHA 2FORA 3N1WF 4LTVA 5DGMF 2F94F 4Q23A 5E8LA 3WC9A 1HM4A 3ACYA 4JVJF 1VG4A 5B0MA 4N1ZF 5HNAA 1KIZA 1UBWA 3OABA 3M00A 3WCMA 2ZCOA 3WCAA 1RQJA 5IMPA 5DGSF 3ICKA 1FPSA 3KRFB 4ZQ8A 5ILJA 3LSNA 4KFAA 4HD1A 4LIXA 4FP4A 3V66A 3TFNA 1N23A 1WL0A 3SDTA 3PKOA 4OKZA 5DW7A 3LZ9A 3TFPA 3WSAA 3EFQA 4DEMF 3NPKA 4JXYA 4N9UA 3WCCA 2EWGA 3OABB 3MAVA 3OYRA 4DZWA 5IK0A 3RYEA 3IBAA 3LGKA 2F92F 4E9UA 3W7FA 3AQBB 4NFJF 5ERMA 4JZXA 1YYQA 3CKEA 5IL8A 3LVSA 3LMDA 1RTRA 4LA6A 2F7MF 3WEHA 4LXWA 4GA3A 3VJBA 5B0LA 1WL3A 4LPHF 4LA5A 1YYSA 2Z78A 4E1EA 5A0JA 1N1BA 5CG6A 2ONGA 2ZCSA 3KRPA 1V4IA 5DGNF 2E8WA 1WKZA 3SDVA 3VJCA 3SAEA 3RBMA 3WEIA 2OA6A 4P0VA 5C05A 2E94A 3G4FA 5IVGA 5ILKA 3WCLA 3M01A 2J1PA 4F6XA 4KPDA 3M02A 1YQ7A 3ACXA 3WCGA 3NPRA 4F62A 3LOMA 4QXSF 4RNQA 5DHIA 1HXGA 4FJQA 5AYPA 1WL2A 3ADZA 2E90A 2E8TA 3UCAA 4NUAA 5DJVF 1DI1A 3TC1A 5JV2F 2ONHA 3KRPB 5IMNA 3KBKA 2PS7A 3NF2A 3VJ9A 3N5JF 5AHUB 4KQSA 3WCFA 3PDEA 5KSXF 4KWDA 3BNYA 2Z4VA 1VG3A 3PYBA 5IM1A 5A0KA 3LJIA 4H5EF 5I1UA 3P5RA 4DI5A 3V1VA 1V4HA 4NKEA 1N21A 3ICNA 1EZFA 2OPMA 4KVDA 3WEFA 1WY0A 4PVXF 3P8LA 4JYXA 5IN8A 2Z50A 3N0FA 4LPGF 3DYFA 5HN7A 3KB9A 1V4KA 3EZ3A 4KQUA 4KQ5A 4LFVF 4NKFA 5DHKA 2AZJA 3S9VA 2PS8A 4KVYA 2P1CA 3G4DA 5EROA 1RQIA 2Z4YA 2ZEUA 1YYUA 4EA0A 4RXDA 2ZCQA 5IKAA 3ICMA 3OACA 4KPJA 2E93A 4P0WA 5IMIA 3WCJA 1YHLA 3ZL6A 4NG6A 2AELA 2QISA 2ZY1A 4KKMA 3WCEA 3N3DA 2E95A 3AE0A 5B03A 4E9ZA 2E8XA 4H5DF 4EA2A 3Q2ZA 5ILDA 1HX9A 5JV1F 2OGDA 4GAXA 4RXAA 4DWBA 3WCIA 3SDQA 4K10A 5HN9A 3MZVA 4OMGA 5DJPF 1YYTA 1UBVA 4PVYF 4LTZA 3OACB 4XQSF 5JUZF 3M0GA 1V4JA 1N22A 4LOBA 1N24A 5AELA 3N5HF 5B0KA 3PYAA 4NFKF 4LFGA 1VG6A 4GP2A 2Q9ZA 3KRCA 3BNXA 4H5CF 3QQVA 5CG5A 1HXCA 2OPNA 2Q58A 3V1XA 3WEGA 3WCDA 4LUUA 2J1OA 3SDRA 5IL3A 4OKMA 3WJKA 3PH7A 3DYGA 5AFXA 5H9DA 4UMJA 3ZMBA 3ZCDA 4KUXA 3IPIA 2PS4A 4JZBA 3S4JA 3EGTA 4RXCA 1VG7A 3RYWA 5IK6A 2ZEVA 1VG2A 5ILIA 5EASA 3LG5A 4DWGA 3AQ0A 5B00A 3VJDA 1N1ZA 4GP1A 5E8KA 2E8UA 3WE9A 3NRIA 3APZA 3KRCB 2O1OA 3ZMCA 1HM7A 3LLWA 4OMHA 1JFGA 1YV5A 4MC0A 2E4OA 2AEKA 3VJ8A 3WSBA 2F89F 3RMGA 4XQTF 2Z52A 5B02A 4QPFA 3ZOUA 3VJEA 4RXEA 3N46F 2J5CA 4JXNA 3N1VF 3SDUA 4LZ3A 4P0XA 2E92A 2I19A 4OGUA 3P41A 1DGPA 3KROA 3N6KF 2VF6A 5A0IA 3TS7A 1YYRA 2AZLA 3N0GA 5EATA 5B01A 5E8HA 3LK5A 3N49F 3ACWA 4MC3A 2H8OA 1UBYA 1PS1A 5ILHA 1KIYA 3Q2QA 3CP6A 1JFAA 2AZKA 2FTZA 1WL1A 3ID0A 5DZ2A 1HXAA 2Z4ZA 5ER8A 3VJAA 4LZ0A 5IKHA 2E8VA 5B0JA 3LGZB 3KROB 3LEEA 2Z7IA 4RYPA 3AQCB 4DHDA 3KRAA 5JA0F 4KK2A 5ILYA 4EA1A 4KVWA 4DXJA 3N45F 5ERNA 1YHMA 4LFEA 3WEJA 4LZCA 4L2XF 3WJOA 4XQRF 2Q80A 1V4EA 2F9KF 5DIQF 3M9UA 5IK9A 3WEKA 2Q9YA 3N3LF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z4W A;  3P8R A;  3LDW A;  1ZW5 A;  1YHK A;  3QKC A;  2PS6 A;  4WK5 A;  4LLT A;  5EAU A;  2PS5 A;  2DH4 A;  4LLS A;  4NFI F;  2F8C F;  1WMW A;  5B0I A;  3Q30 A;  3Q1O A;  5DJR F;  1UBX A;  4KVI A;  3KRA B;  1N20 A;  5HN8 A;  3WCB A;  3ASX A;  2ZCR A;  2F8Z F;  3KRF A;  3WJN A;  1YJ4 A;  3CC9 A;  4F6V A;  3WCH A;  3ICZ A;  2Z4X A;  3B7L A;  3DYH A;  3P5P A;  2E91 A;  4MC8 A;  5ILZ A;  2Z7H A;  3TFV A;  2AET A;  5JV0 F;  2RAH A;  2FOR A;  3N1W F;  4LTV A;  5DGM F;  2F94 F;  4Q23 A;  5E8L A;  3WC9 A;  1HM4 A;  3ACY A;  4JVJ F;  1VG4 A;  5B0M A;  4N1Z F;  5HNA A;  1KIZ A;  1UBW A;  3OAB A;  3M00 A;  3WCM A;  2ZCO A;  3WCA A;  1RQJ A;  5IMP A;  5DGS F;  3ICK A;  1FPS A;  3KRF B;  4ZQ8 A;  5ILJ A;  3LSN A;  4KFA A;  4HD1 A;  4LIX A;  4FP4 A;  3V66 A;  3TFN A;  1N23 A;  1WL0 A;  3SDT A;  3PKO A;  4OKZ A;  5DW7 A;  3LZ9 A;  3TFP A;  3WSA A;  3EFQ A;  4DEM F;  3NPK A;  4JXY A;  4N9U A;  3WCC A;  2EWG A;  3OAB B;  3MAV A;  3OYR A;  4DZW A;  5IK0 A;  3RYE A;  3IBA A;  3LGK A;  2F92 F;  4E9U A;  3W7F A;  3AQB B;  4NFJ F;  5ERM A;  4JZX A;  1YYQ A;  3CKE A;  5IL8 A;  3LVS A;  3LMD A;  1RTR A;  4LA6 A;  2F7M F;  3WEH A;  4LXW A;  4GA3 A;  3VJB A;  5B0L A;  1WL3 A;  4LPH F;  4LA5 A;  1YYS A;  2Z78 A;  4E1E A;  5A0J A;  1N1B A;  5CG6 A;  2ONG A;  2ZCS A;  3KRP A;  1V4I A;  5DGN F;  2E8W A;  1WKZ A;  3SDV A;  3VJC A;  3SAE A;  3RBM A;  3WEI A;  2OA6 A;  4P0V A;  5C05 A;  2E94 A;  3G4F A;  5IVG A;  5ILK A;  3WCL A;  3M01 A;  2J1P A;  4F6X A;  4KPD A;  3M02 A;  1YQ7 A;  3ACX A;  3WCG A;  3NPR A;  4F62 A;  3LOM A;  4QXS F;  4RNQ A;  5DHI A;  1HXG A;  4FJQ A;  5AYP A;  1WL2 A;  3ADZ A;  2E90 A;  2E8T A;  3UCA A;  4NUA A;  5DJV F;  1DI1 A;  3TC1 A;  5JV2 F;  2ONH A;  3KRP B;  5IMN A;  3KBK A;  2PS7 A;  3NF2 A;  3VJ9 A;  3N5J F;  5AHU B;  4KQS A;  3WCF A;  3PDE A;  5KSX F;  4KWD A;  3BNY A;  2Z4V A;  1VG3 A;  3PYB A;  5IM1 A;  5A0K A;  3LJI A;  4H5E F;  5I1U A;  3P5R A;  4DI5 A;  3V1V A;  1V4H A;  4NKE A;  1N21 A;  3ICN A;  1EZF A;  2OPM A;  4KVD A;  3WEF A;  1WY0 A;  4PVX F;  3P8L A;  4JYX A;  5IN8 A;  2Z50 A;  3N0F A;  4LPG F;  3DYF A;  5HN7 A;  3KB9 A;  1V4K A;  3EZ3 A;  4KQU A;  4KQ5 A;  4LFV F;  4NKF A;  5DHK A;  2AZJ A;  3S9V A;  2PS8 A;  4KVY A;  2P1C A;  3G4D A;  5ERO A;  1RQI A;  2Z4Y A;  2ZEU A;  1YYU A;  4EA0 A;  4RXD A;  2ZCQ A;  5IKA A;  3ICM A;  3OAC A;  4KPJ A;  2E93 A;  4P0W A;  5IMI A;  3WCJ A;  1YHL A;  3ZL6 A;  4NG6 A;  2AEL A;  2QIS A;  2ZY1 A;  4KKM A;  3WCE A;  3N3D A;  2E95 A;  3AE0 A;  5B03 A;  4E9Z A;  2E8X A;  4H5D F;  4EA2 A;  3Q2Z A;  5ILD A;  1HX9 A;  5JV1 F;  2OGD A;  4GAX A;  4RXA A;  4DWB A;  3WCI A;  3SDQ A;  4K10 A;  5HN9 A;  3MZV A;  4OMG A;  5DJP F;  1YYT A;  1UBV A;  4PVY F;  4LTZ A;  3OAC B;  4XQS F;  5JUZ F;  3M0G A;  1V4J A;  1N22 A;  4LOB A;  1N24 A;  5AEL A;  3N5H F;  5B0K A;  3PYA A;  4NFK F;  4LFG A;  1VG6 A;  4GP2 A;  2Q9Z A;  3KRC A;  3BNX A;  4H5C F;  3QQV A;  5CG5 A;  1HXC A;  2OPN A;  2Q58 A;  3V1X A;  3WEG A;  3WCD A;  4LUU A;  2J1O A;  3SDR A;  5IL3 A;  4OKM A;  3WJK A;  3PH7 A;  3DYG A;  5AFX A;  5H9D A;  4UMJ A;  3ZMB A;  3ZCD A;  4KUX A;  3IPI A;  2PS4 A;  4JZB A;  3S4J A;  3EGT A;  4RXC A;  1VG7 A;  3RYW A;  5IK6 A;  2ZEV A;  1VG2 A;  5ILI A;  5EAS A;  3LG5 A;  4DWG A;  3AQ0 A;  5B00 A;  3VJD A;  1N1Z A;  4GP1 A;  5E8K A;  2E8U A;  3WE9 A;  3NRI A;  3APZ A;  3KRC B;  2O1O A;  3ZMC A;  1HM7 A;  3LLW A;  4OMH A;  1JFG A;  1YV5 A;  4MC0 A;  2E4O A;  2AEK A;  3VJ8 A;  3WSB A;  2F89 F;  3RMG A;  4XQT F;  2Z52 A;  5B02 A;  4QPF A;  3ZOU A;  3VJE A;  4RXE A;  3N46 F;  2J5C A;  4JXN A;  3N1V F;  3SDU A;  4LZ3 A;  4P0X A;  2E92 A;  2I19 A;  4OGU A;  3P41 A;  1DGP A;  3KRO A;  3N6K F;  2VF6 A;  5A0I A;  3TS7 A;  1YYR A;  2AZL A;  3N0G A;  5EAT A;  5B01 A;  5E8H A;  3LK5 A;  3N49 F;  3ACW A;  4MC3 A;  2H8O A;  1UBY A;  1PS1 A;  5ILH A;  1KIY A;  3Q2Q A;  3CP6 A;  1JFA A;  2AZK A;  2FTZ A;  1WL1 A;  3ID0 A;  5DZ2 A;  1HXA A;  2Z4Z A;  5ER8 A;  3VJA A;  4LZ0 A;  5IKH A;  2E8V A;  5B0J A;  3LGZ B;  3KRO B;  3LEE A;  2Z7I A;  4RYP A;  3AQC B;  4DHD A;  3KRA A;  5JA0 F;  4KK2 A;  5ILY A;  4EA1 A;  4KVW A;  4DXJ A;  3N45 F;  5ERN A;  1YHM A;  4LFE A;  3WEJ A;  4LZC A;  4L2X F;  3WJO A;  4XQR F;  2Q80 A;  1V4E A;  2F9K F;  5DIQ F;  3M9U A;  5IK9 A;  3WEK A;  2Q9Y A;  3N3L F; 
#chains in the Genus database with same CATH topology
 2Z4W A;  3P8R A;  3LDW A;  1ZW5 A;  1YHK A;  3QKC A;  2PS6 A;  4WK5 A;  4LLT A;  5EAU A;  2PS5 A;  2DH4 A;  4LLS A;  4NFI F;  2F8C F;  1WMW A;  5B0I A;  3Q30 A;  3Q1O A;  5DJR F;  1UBX A;  4KVI A;  3KRA B;  1N20 A;  5HN8 A;  3WCB A;  3ASX A;  2ZCR A;  2F8Z F;  3KRF A;  3WJN A;  1YJ4 A;  3CC9 A;  4F6V A;  3WCH A;  3ICZ A;  2Z4X A;  3B7L A;  3DYH A;  3P5P A;  2E91 A;  4MC8 A;  5ILZ A;  2Z7H A;  3TFV A;  2AET A;  5JV0 F;  2RAH A;  2FOR A;  3N1W F;  4LTV A;  5DGM F;  2F94 F;  4Q23 A;  5E8L A;  3WC9 A;  1HM4 A;  3ACY A;  4JVJ F;  1VG4 A;  5B0M A;  4N1Z F;  5HNA A;  1KIZ A;  1UBW A;  3OAB A;  3M00 A;  3WCM A;  2ZCO A;  3WCA A;  1RQJ A;  5IMP A;  5DGS F;  3ICK A;  1FPS A;  3KRF B;  4ZQ8 A;  5ILJ A;  3LSN A;  4KFA A;  4HD1 A;  4LIX A;  4FP4 A;  3V66 A;  3TFN A;  1N23 A;  1WL0 A;  3SDT A;  3PKO A;  4OKZ A;  5DW7 A;  3LZ9 A;  3TFP A;  3WSA A;  3EFQ A;  4DEM F;  3NPK A;  4JXY A;  4N9U A;  3WCC A;  2EWG A;  3OAB B;  3MAV A;  3OYR A;  4DZW A;  5IK0 A;  3RYE A;  3IBA A;  3LGK A;  2F92 F;  4E9U A;  3W7F A;  3AQB B;  4NFJ F;  5ERM A;  4JZX A;  1YYQ A;  3CKE A;  5IL8 A;  3LVS A;  3LMD A;  1RTR A;  4LA6 A;  2F7M F;  3WEH A;  4LXW A;  4GA3 A;  3VJB A;  5B0L A;  1WL3 A;  4LPH F;  4LA5 A;  1YYS A;  2Z78 A;  4E1E A;  5A0J A;  1N1B A;  5CG6 A;  2ONG A;  2ZCS A;  3KRP A;  1V4I A;  5DGN F;  2E8W A;  1WKZ A;  3SDV A;  3VJC A;  3SAE A;  3RBM A;  3WEI A;  2OA6 A;  4P0V A;  5C05 A;  2E94 A;  3G4F A;  5IVG A;  5ILK A;  3WCL A;  3M01 A;  2J1P A;  4F6X A;  4KPD A;  3M02 A;  1YQ7 A;  3ACX A;  3WCG A;  3NPR A;  4F62 A;  3LOM A;  4QXS F;  4RNQ A;  5DHI A;  1HXG A;  4FJQ A;  5AYP A;  1WL2 A;  3ADZ A;  2E90 A;  2E8T A;  3UCA A;  4NUA A;  5DJV F;  1DI1 A;  3TC1 A;  5JV2 F;  2ONH A;  3KRP B;  5IMN A;  3KBK A;  2PS7 A;  3NF2 A;  3VJ9 A;  3N5J F;  5AHU B;  4KQS A;  3WCF A;  3PDE A;  5KSX F;  4KWD A;  3BNY A;  2Z4V A;  1VG3 A;  3PYB A;  5IM1 A;  5A0K A;  3LJI A;  4H5E F;  5I1U A;  3P5R A;  4DI5 A;  3V1V A;  1V4H A;  4NKE A;  1N21 A;  3ICN A;  1EZF A;  2OPM A;  4KVD A;  3WEF A;  1WY0 A;  4PVX F;  3P8L A;  4JYX A;  5IN8 A;  2Z50 A;  3N0F A;  4LPG F;  3DYF A;  5HN7 A;  3KB9 A;  1V4K A;  3EZ3 A;  4KQU A;  4KQ5 A;  4LFV F;  4NKF A;  5DHK A;  2AZJ A;  3S9V A;  2PS8 A;  4KVY A;  2P1C A;  3G4D A;  5ERO A;  1RQI A;  2Z4Y A;  2ZEU A;  1YYU A;  4EA0 A;  4RXD A;  2ZCQ A;  5IKA A;  3ICM A;  3OAC A;  4KPJ A;  2E93 A;  4P0W A;  5IMI A;  3WCJ A;  1YHL A;  3ZL6 A;  4NG6 A;  2AEL A;  2QIS A;  2ZY1 A;  4KKM A;  3WCE A;  3N3D A;  2E95 A;  3AE0 A;  5B03 A;  4E9Z A;  2E8X A;  4H5D F;  4EA2 A;  3Q2Z A;  5ILD A;  1HX9 A;  5JV1 F;  2OGD A;  4GAX A;  4RXA A;  4DWB A;  3WCI A;  3SDQ A;  4K10 A;  5HN9 A;  3MZV A;  4OMG A;  5DJP F;  1YYT A;  1UBV A;  4PVY F;  4LTZ A;  3OAC B;  4XQS F;  5JUZ F;  3M0G A;  1V4J A;  1N22 A;  4LOB A;  1N24 A;  5AEL A;  3N5H F;  5B0K A;  3PYA A;  4NFK F;  4LFG A;  1VG6 A;  4GP2 A;  2Q9Z A;  3KRC A;  3BNX A;  4H5C F;  3QQV A;  5CG5 A;  1HXC A;  2OPN A;  2Q58 A;  3V1X A;  3WEG A;  3WCD A;  4LUU A;  2J1O A;  3SDR A;  5IL3 A;  4OKM A;  3WJK A;  3PH7 A;  3DYG A;  5AFX A;  5H9D A;  4UMJ A;  3ZMB A;  3ZCD A;  4KUX A;  3IPI A;  2PS4 A;  4JZB A;  3S4J A;  3EGT A;  4RXC A;  1VG7 A;  3RYW A;  5IK6 A;  2ZEV A;  1VG2 A;  5ILI A;  5EAS A;  3LG5 A;  4DWG A;  3AQ0 A;  5B00 A;  3VJD A;  1N1Z A;  4GP1 A;  5E8K A;  2E8U A;  3WE9 A;  3NRI A;  3APZ A;  3KRC B;  2O1O A;  3ZMC A;  1HM7 A;  3LLW A;  4OMH A;  1JFG A;  1YV5 A;  4MC0 A;  2E4O A;  2AEK A;  3VJ8 A;  3WSB A;  2F89 F;  3RMG A;  4XQT F;  2Z52 A;  5B02 A;  4QPF A;  3ZOU A;  3VJE A;  4RXE A;  3N46 F;  2J5C A;  4JXN A;  3N1V F;  3SDU A;  4LZ3 A;  4P0X A;  2E92 A;  2I19 A;  4OGU A;  3P41 A;  1DGP A;  3KRO A;  3N6K F;  2VF6 A;  5A0I A;  3TS7 A;  1YYR A;  2AZL A;  3N0G A;  5EAT A;  5B01 A;  5E8H A;  3LK5 A;  3N49 F;  3ACW A;  4MC3 A;  2H8O A;  1UBY A;  1PS1 A;  5ILH A;  1KIY A;  3Q2Q A;  3CP6 A;  1JFA A;  2AZK A;  2FTZ A;  1WL1 A;  3ID0 A;  5DZ2 A;  1HXA A;  2Z4Z A;  5ER8 A;  3VJA A;  4LZ0 A;  5IKH A;  2E8V A;  5B0J A;  3LGZ B;  3KRO B;  3LEE A;  2Z7I A;  4RYP A;  3AQC B;  4DHD A;  3KRA A;  5JA0 F;  4KK2 A;  5ILY A;  4EA1 A;  4KVW A;  4DXJ A;  3N45 F;  5ERN A;  1YHM A;  4LFE A;  3WEJ A;  4LZC A;  4L2X F;  3WJO A;  4XQR F;  2Q80 A;  1V4E A;  2F9K F;  5DIQ F;  3M9U A;  5IK9 A;  3WEK A;  2Q9Y A;  3N3L F; 
#chains in the Genus database with same CATH homology
 2Z4W A;  3P8R A;  3LDW A;  1ZW5 A;  1YHK A;  3QKC A;  2PS6 A;  4WK5 A;  4LLT A;  5EAU A;  2PS5 A;  2DH4 A;  4LLS A;  4NFI F;  2F8C F;  1WMW A;  5B0I A;  3Q30 A;  3Q1O A;  5DJR F;  1UBX A;  4KVI A;  3KRA B;  1N20 A;  5HN8 A;  3WCB A;  3ASX A;  2ZCR A;  2F8Z F;  3KRF A;  3WJN A;  1YJ4 A;  3CC9 A;  4F6V A;  3WCH A;  3ICZ A;  2Z4X A;  3B7L A;  3DYH A;  3P5P A;  2E91 A;  4MC8 A;  5ILZ A;  2Z7H A;  3TFV A;  2AET A;  5JV0 F;  2RAH A;  2FOR A;  3N1W F;  4LTV A;  5DGM F;  2F94 F;  4Q23 A;  5E8L A;  3WC9 A;  1HM4 A;  3ACY A;  4JVJ F;  1VG4 A;  5B0M A;  4N1Z F;  5HNA A;  1KIZ A;  1UBW A;  3OAB A;  3M00 A;  3WCM A;  2ZCO A;  3WCA A;  1RQJ A;  5IMP A;  5DGS F;  3ICK A;  1FPS A;  3KRF B;  4ZQ8 A;  5ILJ A;  3LSN A;  4KFA A;  4HD1 A;  4LIX A;  4FP4 A;  3V66 A;  3TFN A;  1N23 A;  1WL0 A;  3SDT A;  3PKO A;  4OKZ A;  5DW7 A;  3LZ9 A;  3TFP A;  3WSA A;  3EFQ A;  4DEM F;  3NPK A;  4JXY A;  4N9U A;  3WCC A;  2EWG A;  3OAB B;  3MAV A;  3OYR A;  4DZW A;  5IK0 A;  3RYE A;  3IBA A;  3LGK A;  2F92 F;  4E9U A;  3W7F A;  3AQB B;  4NFJ F;  5ERM A;  4JZX A;  1YYQ A;  3CKE A;  5IL8 A;  3LVS A;  3LMD A;  1RTR A;  4LA6 A;  2F7M F;  3WEH A;  4LXW A;  4GA3 A;  3VJB A;  5B0L A;  1WL3 A;  4LPH F;  4LA5 A;  1YYS A;  2Z78 A;  4E1E A;  5A0J A;  1N1B A;  5CG6 A;  2ONG A;  2ZCS A;  3KRP A;  1V4I A;  5DGN F;  2E8W A;  1WKZ A;  3SDV A;  3VJC A;  3SAE A;  3RBM A;  3WEI A;  2OA6 A;  4P0V A;  5C05 A;  2E94 A;  3G4F A;  5IVG A;  5ILK A;  3WCL A;  3M01 A;  2J1P A;  4F6X A;  4KPD A;  3M02 A;  1YQ7 A;  3ACX A;  3WCG A;  3NPR A;  4F62 A;  3LOM A;  4QXS F;  4RNQ A;  5DHI A;  1HXG A;  4FJQ A;  5AYP A;  1WL2 A;  3ADZ A;  2E90 A;  2E8T A;  3UCA A;  4NUA A;  5DJV F;  1DI1 A;  3TC1 A;  5JV2 F;  2ONH A;  3KRP B;  5IMN A;  3KBK A;  2PS7 A;  3NF2 A;  3VJ9 A;  3N5J F;  5AHU B;  4KQS A;  3WCF A;  3PDE A;  5KSX F;  4KWD A;  3BNY A;  2Z4V A;  1VG3 A;  3PYB A;  5IM1 A;  5A0K A;  3LJI A;  4H5E F;  5I1U A;  3P5R A;  4DI5 A;  3V1V A;  1V4H A;  4NKE A;  1N21 A;  3ICN A;  1EZF A;  2OPM A;  4KVD A;  3WEF A;  1WY0 A;  4PVX F;  3P8L A;  4JYX A;  5IN8 A;  2Z50 A;  3N0F A;  4LPG F;  3DYF A;  5HN7 A;  3KB9 A;  1V4K A;  3EZ3 A;  4KQU A;  4KQ5 A;  4LFV F;  4NKF A;  5DHK A;  2AZJ A;  3S9V A;  2PS8 A;  4KVY A;  2P1C A;  3G4D A;  5ERO A;  1RQI A;  2Z4Y A;  2ZEU A;  1YYU A;  4EA0 A;  4RXD A;  2ZCQ A;  5IKA A;  3ICM A;  3OAC A;  4KPJ A;  2E93 A;  4P0W A;  5IMI A;  3WCJ A;  1YHL A;  3ZL6 A;  4NG6 A;  2AEL A;  2QIS A;  2ZY1 A;  4KKM A;  3WCE A;  3N3D A;  2E95 A;  3AE0 A;  5B03 A;  4E9Z A;  2E8X A;  4H5D F;  4EA2 A;  3Q2Z A;  5ILD A;  1HX9 A;  5JV1 F;  2OGD A;  4GAX A;  4RXA A;  4DWB A;  3WCI A;  3SDQ A;  4K10 A;  5HN9 A;  3MZV A;  4OMG A;  5DJP F;  1YYT A;  1UBV A;  4PVY F;  4LTZ A;  3OAC B;  4XQS F;  5JUZ F;  3M0G A;  1V4J A;  1N22 A;  4LOB A;  1N24 A;  5AEL A;  3N5H F;  5B0K A;  3PYA A;  4NFK F;  4LFG A;  1VG6 A;  4GP2 A;  2Q9Z A;  3KRC A;  3BNX A;  4H5C F;  3QQV A;  5CG5 A;  1HXC A;  2OPN A;  2Q58 A;  3V1X A;  3WEG A;  3WCD A;  4LUU A;  2J1O A;  3SDR A;  5IL3 A;  4OKM A;  3WJK A;  3PH7 A;  3DYG A;  5AFX A;  5H9D A;  4UMJ A;  3ZMB A;  3ZCD A;  4KUX A;  3IPI A;  2PS4 A;  4JZB A;  3S4J A;  3EGT A;  4RXC A;  1VG7 A;  3RYW A;  5IK6 A;  2ZEV A;  1VG2 A;  5ILI A;  5EAS A;  3LG5 A;  4DWG A;  3AQ0 A;  5B00 A;  3VJD A;  1N1Z A;  4GP1 A;  5E8K A;  2E8U A;  3WE9 A;  3NRI A;  3APZ A;  3KRC B;  2O1O A;  3ZMC A;  1HM7 A;  3LLW A;  4OMH A;  1JFG A;  1YV5 A;  4MC0 A;  2E4O A;  2AEK A;  3VJ8 A;  3WSB A;  2F89 F;  3RMG A;  4XQT F;  2Z52 A;  5B02 A;  4QPF A;  3ZOU A;  3VJE A;  4RXE A;  3N46 F;  2J5C A;  4JXN A;  3N1V F;  3SDU A;  4LZ3 A;  4P0X A;  2E92 A;  2I19 A;  4OGU A;  3P41 A;  1DGP A;  3KRO A;  3N6K F;  2VF6 A;  5A0I A;  3TS7 A;  1YYR A;  2AZL A;  3N0G A;  5EAT A;  5B01 A;  5E8H A;  3LK5 A;  3N49 F;  3ACW A;  4MC3 A;  2H8O A;  1UBY A;  1PS1 A;  5ILH A;  1KIY A;  3Q2Q A;  3CP6 A;  1JFA A;  2AZK A;  2FTZ A;  1WL1 A;  3ID0 A;  5DZ2 A;  1HXA A;  2Z4Z A;  5ER8 A;  3VJA A;  4LZ0 A;  5IKH A;  2E8V A;  5B0J A;  3LGZ B;  3KRO B;  3LEE A;  2Z7I A;  4RYP A;  3AQC B;  4DHD A;  3KRA A;  5JA0 F;  4KK2 A;  5ILY A;  4EA1 A;  4KVW A;  4DXJ A;  3N45 F;  5ERN A;  1YHM A;  4LFE A;  3WEJ A;  4LZC A;  4L2X F;  3WJO A;  4XQR F;  2Q80 A;  1V4E A;  2F9K F;  5DIQ F;  3M9U A;  5IK9 A;  3WEK A;  2Q9Y A;  3N3L F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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