5AWCA

Crystal structure of human tlr8 in complex with mb-564
Total Genus 251
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
251
sequence length
788
structure length
749
Chain Sequence
b'SRSYPCDEKKQVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSLE'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Toll-like receptor 8
publication title Structure-based Design of Human TLR8-specific Agonists with Augmented Potency and Adjuvanticity
rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 251
structure length 749
sequence length 788
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2015-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 5awcA00
4NKHA 4CC4C 2OMWA 4Z61C 4LSXA 2OMTA 3ULUA 4PKIG 4FDWA 4Q3GA 3RFSA 5GQRK 1D0BA 1OTMA 4L3AA 3RGXA 4TZHA 2OMUA 3GOZA 2WQVA 4M7EA 3W3LA 5AWBA 4KT1A 5GMFA 4Y61B 4ARNA 3JB9j 1A9NA 3E3ZA 4ECNA 4XGOA 4K17A 3W3NA 5AWAA 1O6VA 1OTOA 4Z8GA 3FXIA 4R6AA 4R07A 4Z64C 4LSCA 2P1OB 4C2BB 4QBZA 2R9UA 1SQ0B 3M19A 4WP6A 1K5DC 2P1PB 4LSAA 3O6NA 2IFGA 4FHOA 4PQ8A 3G3BA 3UL7A 3CIYA 5B0TA 4G8AA 4P8SA 3BZ5A 4I6JB 2P1MB 4WYKA 4RCWA 2WQWA 3RFJA 2Q4GW 1M0ZA 1OGQA 2ELLA 4LSXC 3SB4A 2Y5QA 1KOOA 2O6RA 5AWCA 4GT6A 3RJ0A 4R58A 1DFJI 5GMGA 4P91A 3CIGA 1OOKG 5CMPA 2Z82A 2UZXA 1G9UA 1FQVA 4BSUA 4LXSA 4QC0A 3E2JA 5A5CA 1DCEA 2WQXA 5D3IA 3RGZA 1O6TA 3ULVA 1H6UA 4R09A 2JE1A 4FD0A 1XKUA 2P1QB 4U7LA 1PGVA 3E4GA 2RR6A 2Z7XA 4H09A 3OGMB 1GWBA 3RIZA 1K5GC 4R0AA 1IO0A 4PSJA 3UL9A 1LTXA 2BNHA 5FTTB 3PMHG 1FS2A 4FCGA 5IYXC 3REZA 4BSRA 3WPDA 4BSSA 1P8VA 5LFNA 2P1NB 5AWDA 3G06A 3OGKB 1M9SA 5IJCA 1U0ND 3WPGA 5B0NA 3TSRE 3CVRA 4V2DA 1H6TA 4R08A 3G3AA 4V2CA 3WPEA 4CILA 2WQUA 4HQ1A 1A4YA 2Z62A 2Z65A 3G39A 4RWTC 4PEQB 4KXFB 1FO1A 3W3JA 3WPCA 4U06A 2WFHA 3WPHA 5IJDA 1XECA 2V70A 3ZYNA 4GLPA 1ZIWA 4ECOA 3G04C 4RCAB 1Z7XW 5HZLB 3DZEA 4M7EC 4C2AB 1M9LA 4UFRA 2FT3A 3RFEA 3E6JA 2A0ZA 5HDHA 3ZYOA 4Z79A 4Z94G 3VQ2A 3UL8A 2CA6A 4L3FA 2O6QA 1P8TA 4LI2A 1W8AA 2ASTB 5GS2B 1OZNA 3UN9A 2Z63A 3P72A 5AZ5A 3WPIA 4QXEA 4CNMA 3W3MA 4LI1A 4B8CD 5B4PA 4U09A 1FT8A 1XWDC 4R6JA 2ASSB 4YEBB 1P9AG 3ULAA 5IJBA 3OGLB 2JE0A 2OMXA 1OTNA 4KNGA 3RW6A 1JL5A 1WWLA 1DS9A 2Z66A 3C6OB 1O6SA 4AY9X 4CC4A 1YRGA 3ZYIA 4PERA 3KJ4A 3WN4A 4R6GA 3ZYJA 4R5CA 1QYYA 4OQTA 4XOSA 4Q62A 4BV4R 1KOHA 2UZYA 5CMNA 2XOTA 4CP6A 2JQDA 3C6PB 2BEXA 4LXRA 4IM6A 2OMYA 4ARRA 3C6NB 4CNCA 4J4LA 3VQ1A 4V2EA 4R6FA 2OMZA 3OJAB 4MN8B 2O6SA 1M10B 2V9TB 3WPBA 4XSQA 3W3KA 4J0MA 3O53A 3W3GA 5GS0A 2ID5A 2Z81A 4FS7A 3A79B 4AW4A 2Z64A 4EZGA 3RW7A 1XCDA 3OJAA 4FMZA 2RA8A 4MQWX 2OMVA 2XWTC 1XEUA 4Q3IA 4U08A 5GMHA 2Z7XB 3WPFA 2V9SA 4NKGA 3M18A 4R5DA
chains in the Genus database with same CATH superfamily
4NKHA 4CC4C 2OMWA 4Z61C 4LSXA 2OMTA 3ULUA 4PKIG 4FDWA 4Q3GA 3RFSA 5GQRK 1D0BA 1OTMA 4L3AA 3RGXA 4TZHA 2OMUA 3GOZA 2WQVA 4M7EA 3W3LA 5AWBA 4KT1A 5GMFA 4Y61B 4ARNA 3JB9j 1A9NA 3E3ZA 4ECNA 4XGOA 4K17A 3W3NA 5AWAA 1O6VA 1OTOA 4Z8GA 3FXIA 4R6AA 4R07A 4Z64C 4LSCA 2P1OB 4C2BB 4QBZA 2R9UA 1SQ0B 3M19A 4WP6A 1K5DC 2P1PB 4LSAA 3O6NA 2IFGA 4FHOA 4PQ8A 3G3BA 3UL7A 3CIYA 5B0TA 4G8AA 4P8SA 3BZ5A 4I6JB 2P1MB 4WYKA 4RCWA 2WQWA 3RFJA 2Q4GW 1M0ZA 1OGQA 2ELLA 4LSXC 3SB4A 2Y5QA 1KOOA 2O6RA 5AWCA 4GT6A 3RJ0A 4NZTM 1DFJI 4R58A 5GMGA 4P91A 3CIGA 1OOKG 5CMPA 2Z82A 2UZXA 1G9UA 1FQVA 4BSUA 4LXSA 4QC0A 3E2JA 5A5CA 1DCEA 2WQXA 5D3IA 3RGZA 1O6TA 3ULVA 1H6UA 4R09A 2JE1A 4FD0A 1XKUA 2P1QB 4U7LA 1PGVA 3E4GA 2RR6A 2Z7XA 4H09A 3OGMB 1GWBA 3RIZA 1K5GC 4R0AA 1IO0A 4PSJA 3UL9A 1LTXA 2BNHA 5FTTB 3PMHG 1FS2A 4FCGA 5IYXC 3REZA 4BSRA 3WPDA 4BSSA 1P8VA 5LFNA 2P1NB 5AWDA 3G06A 3OGKB 1M9SA 5IJCA 1U0ND 3WPGA 5B0NA 3TSRE 3CVRA 4V2DA 1H6TA 4R08A 3G3AA 4V2CA 3WPEA 4CILA 2WQUA 4HQ1A 1A4YA 2Z62A 2Z65A 3G39A 4RWTC 4PEQB 4KXFB 1FO1A 3W3JA 3WPCA 4U06A 2WFHA 3WPHA 5IJDA 1XECA 2V70A 3ZYNA 4GLPA 1ZIWA 4ECOA 3G04C 4RCAB 1Z7XW 5HZLB 3DZEA 4M7EC 4C2AB 1M9LA 4UFRA 2FT3A 3RFEA 3E6JA 2A0ZA 5HDHA 3ZYOA 4Z79A 4Z94G 3VQ2A 3UL8A 2CA6A 4L3FA 2O6QA 1P8TA 4LI2A 1W8AA 2ASTB 5GS2B 1OZNA 3UN9A 2Z63A 3P72A 5AZ5A 3WPIA 4QXEA 4CNMA 3W3MA 4LI1A 4B8CD 5B4PA 4U09A 1FT8A 1XWDC 4R6JA 2ASSB 4YEBB 1P9AG 3ULAA 5IJBA 3OGLB 2JE0A 2OMXA 1OTNA 4KNGA 3RW6A 1JL5A 1WWLA 1DS9A 2Z66A 3C6OB 1O6SA 4AY9X 4CC4A 1YRGA 3ZYIA 4PERA 3KJ4A 3WN4A 4R6GA 3ZYJA 4R5CA 1QYYA 4OQTA 4XOSA 4Q62A 4BV4R 1KOHA 2UZYA 5CMNA 2XOTA 4CP6A 2JQDA 3C6PB 2BEXA 4LXRA 4IM6A 2OMYA 4ARRA 3C6NB 4CNCA 4J4LA 4NZRM 3VQ1A 4V2EA 4R6FA 2OMZA 3OJAB 4MN8B 2O6SA 1M10B 2V9TB 3WPBA 4XSQA 3W3KA 4J0MA 3O53A 3W3GA 5GS0A 2ID5A 2Z81A 4FS7A 3A79B 4AW4A 2Z64A 4EZGA 3RW7A 1XCDA 3OJAA 4FMZA 2RA8A 4MQWX 2OMVA 2XWTC 1XEUA 4Q3IA 4U08A 5GMHA 2Z7XB 3WPFA 2V9SA 4NKGA 3M18A 4R5DA
chains in the Genus database with same CATH topology
4NKHA 4CC4C 2OMWA 4Z61C 4LSXA 2OMTA 3ULUA 4PKIG 4FDWA 4Q3GA 3RFSA 5GQRK 1D0BA 1OTMA 4L3AA 3RGXA 4TZHA 2OMUA 3GOZA 2WQVA 4M7EA 3W3LA 5AWBA 4KT1A 5GMFA 4Y61B 4ARNA 3JB9j 1A9NA 3E3ZA 4ECNA 4XGOA 4K17A 3W3NA 5AWAA 1O6VA 1OTOA 4Z8GA 3FXIA 4R6AA 4R07A 4Z64C 4LSCA 2P1OB 4C2BB 4QBZA 2R9UA 1SQ0B 3M19A 4WP6A 1K5DC 2P1PB 4LSAA 3O6NA 2IFGA 4FHOA 4PQ8A 3G3BA 3UL7A 3CIYA 5B0TA 4G8AA 4P8SA 3BZ5A 4I6JB 2P1MB 4WYKA 4RCWA 2WQWA 3RFJA 2Q4GW 1M0ZA 1OGQA 2ELLA 4LSXC 3SB4A 2Y5QA 1KOOA 2O6RA 5AWCA 4GT6A 3RJ0A 4R58A 1DFJI 5GMGA 4P91A 3CIGA 1OOKG 5CMPA 2Z82A 2UZXA 1G9UA 1FQVA 4BSUA 4LXSA 4QC0A 3E2JA 5A5CA 1DCEA 2WQXA 5D3IA 3RGZA 1O6TA 3ULVA 1H6UA 4R09A 2JE1A 4FD0A 1XKUA 2P1QB 4U7LA 1PGVA 3E4GA 2RR6A 2Z7XA 4H09A 3OGMB 1GWBA 3RIZA 1K5GC 4R0AA 1IO0A 4PSJA 3UL9A 1LTXA 2BNHA 5FTTB 3PMHG 1FS2A 4FCGA 5IYXC 3REZA 4BSRA 3WPDA 4BSSA 1P8VA 5LFNA 2P1NB 5AWDA 3G06A 3OGKB 1M9SA 5IJCA 1U0ND 3WPGA 5B0NA 3TSRE 3CVRA 4V2DA 1H6TA 4R08A 3G3AA 4V2CA 3WPEA 4CILA 2WQUA 4HQ1A 1A4YA 2Z62A 2Z65A 3G39A 4RWTC 4PEQB 4KXFB 1FO1A 3W3JA 3WPCA 4U06A 2WFHA 3WPHA 5IJDA 1XECA 2V70A 3ZYNA 4GLPA 1ZIWA 4ECOA 3G04C 4RCAB 1Z7XW 5HZLB 3DZEA 4M7EC 4C2AB 1M9LA 4UFRA 2FT3A 3RFEA 3E6JA 2A0ZA 5HDHA 3ZYOA 4Z79A 4Z94G 3VQ2A 3UL8A 2CA6A 4L3FA 2O6QA 1P8TA 4LI2A 1W8AA 2ASTB 5GS2B 1OZNA 3UN9A 2Z63A 3P72A 5AZ5A 3WPIA 4QXEA 4CNMA 3W3MA 4LI1A 4B8CD 5B4PA 4U09A 1FT8A 1XWDC 4R6JA 2ASSB 4YEBB 1P9AG 3ULAA 5IJBA 3OGLB 2JE0A 2OMXA 1OTNA 4KNGA 3RW6A 1JL5A 1WWLA 1DS9A 2Z66A 3C6OB 1O6SA 4AY9X 4CC4A 1YRGA 3ZYIA 4PERA 3KJ4A 3WN4A 4R6GA 3ZYJA 4R5CA 1QYYA 4OQTA 4XOSA 4Q62A 4BV4R 1KOHA 2UZYA 5CMNA 2XOTA 4CP6A 2JQDA 3C6PB 2BEXA 4LXRA 4IM6A 2OMYA 4ARRA 3C6NB 4CNCA 4J4LA 3VQ1A 4V2EA 4R6FA 2OMZA 3OJAB 4MN8B 2O6SA 1M10B 2V9TB 3WPBA 4XSQA 3W3KA 4J0MA 3O53A 3W3GA 5GS0A 2ID5A 2Z81A 4FS7A 3A79B 4AW4A 2Z64A 4EZGA 3RW7A 1XCDA 3OJAA 4FMZA 2RA8A 4MQWX 2OMVA 2XWTC 1XEUA 4Q3IA 4U08A 5GMHA 2Z7XB 3WPFA 2V9SA 4NKGA 3M18A 4R5DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NKH A;  4CC4 C;  2OMW A;  4Z61 C;  4LSX A;  2OMT A;  3ULU A;  4PKI G;  4FDW A;  4Q3G A;  3RFS A;  5GQR K;  1D0B A;  1OTM A;  4L3A A;  3RGX A;  4TZH A;  2OMU A;  3GOZ A;  2WQV A;  4M7E A;  3W3L A;  5AWB A;  4KT1 A;  5GMF A;  4Y61 B;  4ARN A;  3JB9 j;  1A9N A;  3E3Z A;  4ECN A;  4XGO A;  4K17 A;  3W3N A;  5AWA A;  1O6V A;  1OTO A;  4Z8G A;  3FXI A;  4R6A A;  4R07 A;  4Z64 C;  4LSC A;  2P1O B;  4C2B B;  4QBZ A;  2R9U A;  1SQ0 B;  3M19 A;  4WP6 A;  1K5D C;  2P1P B;  4LSA A;  3O6N A;  2IFG A;  4FHO A;  4PQ8 A;  3G3B A;  3UL7 A;  3CIY A;  5B0T A;  4G8A A;  4P8S A;  3BZ5 A;  4I6J B;  2P1M B;  4WYK A;  4RCW A;  2WQW A;  3RFJ A;  2Q4G W;  1M0Z A;  1OGQ A;  2ELL A;  4LSX C;  3SB4 A;  2Y5Q A;  1KOO A;  2O6R A;  5AWC A;  4GT6 A;  3RJ0 A;  4R58 A;  1DFJ I;  5GMG A;  4P91 A;  3CIG A;  1OOK G;  5CMP A;  2Z82 A;  2UZX A;  1G9U A;  1FQV A;  4BSU A;  4LXS A;  4QC0 A;  3E2J A;  5A5C A;  1DCE A;  2WQX A;  5D3I A;  3RGZ A;  1O6T A;  3ULV A;  1H6U A;  4R09 A;  2JE1 A;  4FD0 A;  1XKU A;  2P1Q B;  4U7L A;  1PGV A;  3E4G A;  2RR6 A;  2Z7X A;  4H09 A;  3OGM B;  1GWB A;  3RIZ A;  1K5G C;  4R0A A;  1IO0 A;  4PSJ A;  3UL9 A;  1LTX A;  2BNH A;  5FTT B;  3PMH G;  1FS2 A;  4FCG A;  5IYX C;  3REZ A;  4BSR A;  3WPD A;  4BSS A;  1P8V A;  5LFN A;  2P1N B;  5AWD A;  3G06 A;  3OGK B;  1M9S A;  5IJC A;  1U0N D;  3WPG A;  5B0N A;  3TSR E;  3CVR A;  4V2D A;  1H6T A;  4R08 A;  3G3A A;  4V2C A;  3WPE A;  4CIL A;  2WQU A;  4HQ1 A;  1A4Y A;  2Z62 A;  2Z65 A;  3G39 A;  4RWT C;  4PEQ B;  4KXF B;  1FO1 A;  3W3J A;  3WPC A;  4U06 A;  2WFH A;  3WPH A;  5IJD A;  1XEC A;  2V70 A;  3ZYN A;  4GLP A;  1ZIW A;  4ECO A;  3G04 C;  4RCA B;  1Z7X W;  5HZL B;  3DZE A;  4M7E C;  4C2A B;  1M9L A;  4UFR A;  2FT3 A;  3RFE A;  3E6J A;  2A0Z A;  5HDH A;  3ZYO A;  4Z79 A;  4Z94 G;  3VQ2 A;  3UL8 A;  2CA6 A;  4L3F A;  2O6Q A;  1P8T A;  4LI2 A;  1W8A A;  2AST B;  5GS2 B;  1OZN A;  3UN9 A;  2Z63 A;  3P72 A;  5AZ5 A;  3WPI A;  4QXE A;  4CNM A;  3W3M A;  4LI1 A;  4B8C D;  5B4P A;  4U09 A;  1FT8 A;  1XWD C;  4R6J A;  2ASS B;  4YEB B;  1P9A G;  3ULA A;  5IJB A;  3OGL B;  2JE0 A;  2OMX A;  1OTN A;  4KNG A;  3RW6 A;  1JL5 A;  1WWL A;  1DS9 A;  2Z66 A;  3C6O B;  1O6S A;  4AY9 X;  4CC4 A;  1YRG A;  3ZYI A;  4PER A;  3KJ4 A;  3WN4 A;  4R6G A;  3ZYJ A;  4R5C A;  1QYY A;  4OQT A;  4XOS A;  4Q62 A;  4BV4 R;  1KOH A;  2UZY A;  5CMN A;  2XOT A;  4CP6 A;  2JQD A;  3C6P B;  2BEX A;  4LXR A;  4IM6 A;  2OMY A;  4ARR A;  3C6N B;  4CNC A;  4J4L A;  3VQ1 A;  4V2E A;  4R6F A;  2OMZ A;  3OJA B;  4MN8 B;  2O6S A;  1M10 B;  2V9T B;  3WPB A;  4XSQ A;  3W3K A;  4J0M A;  3O53 A;  3W3G A;  5GS0 A;  2ID5 A;  2Z81 A;  4FS7 A;  3A79 B;  4AW4 A;  2Z64 A;  4EZG A;  3RW7 A;  1XCD A;  3OJA A;  4FMZ A;  2RA8 A;  4MQW X;  2OMV A;  2XWT C;  1XEU A;  4Q3I A;  4U08 A;  5GMH A;  2Z7X B;  3WPF A;  2V9S A;  4NKG A;  3M18 A;  4R5D A; 
#chains in the Genus database with same CATH topology
 4NKH A;  4CC4 C;  2OMW A;  4Z61 C;  4LSX A;  2OMT A;  3ULU A;  4PKI G;  4FDW A;  4Q3G A;  3RFS A;  5GQR K;  1D0B A;  1OTM A;  4L3A A;  3RGX A;  4TZH A;  2OMU A;  3GOZ A;  2WQV A;  4M7E A;  3W3L A;  5AWB A;  4KT1 A;  5GMF A;  4Y61 B;  4ARN A;  3JB9 j;  1A9N A;  3E3Z A;  4ECN A;  4XGO A;  4K17 A;  3W3N A;  5AWA A;  1O6V A;  1OTO A;  4Z8G A;  3FXI A;  4R6A A;  4R07 A;  4Z64 C;  4LSC A;  2P1O B;  4C2B B;  4QBZ A;  2R9U A;  1SQ0 B;  3M19 A;  4WP6 A;  1K5D C;  2P1P B;  4LSA A;  3O6N A;  2IFG A;  4FHO A;  4PQ8 A;  3G3B A;  3UL7 A;  3CIY A;  5B0T A;  4G8A A;  4P8S A;  3BZ5 A;  4I6J B;  2P1M B;  4WYK A;  4RCW A;  2WQW A;  3RFJ A;  2Q4G W;  1M0Z A;  1OGQ A;  2ELL A;  4LSX C;  3SB4 A;  2Y5Q A;  1KOO A;  2O6R A;  5AWC A;  4GT6 A;  3RJ0 A;  4NZT M;  1DFJ I;  4R58 A;  5GMG A;  4P91 A;  3CIG A;  1OOK G;  5CMP A;  2Z82 A;  2UZX A;  1G9U A;  1FQV A;  4BSU A;  4LXS A;  4QC0 A;  3E2J A;  5A5C A;  1DCE A;  2WQX A;  5D3I A;  3RGZ A;  1O6T A;  3ULV A;  1H6U A;  4R09 A;  2JE1 A;  4FD0 A;  1XKU A;  2P1Q B;  4U7L A;  1PGV A;  3E4G A;  2RR6 A;  2Z7X A;  4H09 A;  3OGM B;  1GWB A;  3RIZ A;  1K5G C;  4R0A A;  1IO0 A;  4PSJ A;  3UL9 A;  1LTX A;  2BNH A;  5FTT B;  3PMH G;  1FS2 A;  4FCG A;  5IYX C;  3REZ A;  4BSR A;  3WPD A;  4BSS A;  1P8V A;  5LFN A;  2P1N B;  5AWD A;  3G06 A;  3OGK B;  1M9S A;  5IJC A;  1U0N D;  3WPG A;  5B0N A;  3TSR E;  3CVR A;  4V2D A;  1H6T A;  4R08 A;  3G3A A;  4V2C A;  3WPE A;  4CIL A;  2WQU A;  4HQ1 A;  1A4Y A;  2Z62 A;  2Z65 A;  3G39 A;  4RWT C;  4PEQ B;  4KXF B;  1FO1 A;  3W3J A;  3WPC A;  4U06 A;  2WFH A;  3WPH A;  5IJD A;  1XEC A;  2V70 A;  3ZYN A;  4GLP A;  1ZIW A;  4ECO A;  3G04 C;  4RCA B;  1Z7X W;  5HZL B;  3DZE A;  4M7E C;  4C2A B;  1M9L A;  4UFR A;  2FT3 A;  3RFE A;  3E6J A;  2A0Z A;  5HDH A;  3ZYO A;  4Z79 A;  4Z94 G;  3VQ2 A;  3UL8 A;  2CA6 A;  4L3F A;  2O6Q A;  1P8T A;  4LI2 A;  1W8A A;  2AST B;  5GS2 B;  1OZN A;  3UN9 A;  2Z63 A;  3P72 A;  5AZ5 A;  3WPI A;  4QXE A;  4CNM A;  3W3M A;  4LI1 A;  4B8C D;  5B4P A;  4U09 A;  1FT8 A;  1XWD C;  4R6J A;  2ASS B;  4YEB B;  1P9A G;  3ULA A;  5IJB A;  3OGL B;  2JE0 A;  2OMX A;  1OTN A;  4KNG A;  3RW6 A;  1JL5 A;  1WWL A;  1DS9 A;  2Z66 A;  3C6O B;  1O6S A;  4AY9 X;  4CC4 A;  1YRG A;  3ZYI A;  4PER A;  3KJ4 A;  3WN4 A;  4R6G A;  3ZYJ A;  4R5C A;  1QYY A;  4OQT A;  4XOS A;  4Q62 A;  4BV4 R;  1KOH A;  2UZY A;  5CMN A;  2XOT A;  4CP6 A;  2JQD A;  3C6P B;  2BEX A;  4LXR A;  4IM6 A;  2OMY A;  4ARR A;  3C6N B;  4CNC A;  4J4L A;  4NZR M;  3VQ1 A;  4V2E A;  4R6F A;  2OMZ A;  3OJA B;  4MN8 B;  2O6S A;  1M10 B;  2V9T B;  3WPB A;  4XSQ A;  3W3K A;  4J0M A;  3O53 A;  3W3G A;  5GS0 A;  2ID5 A;  2Z81 A;  4FS7 A;  3A79 B;  4AW4 A;  2Z64 A;  4EZG A;  3RW7 A;  1XCD A;  3OJA A;  4FMZ A;  2RA8 A;  4MQW X;  2OMV A;  2XWT C;  1XEU A;  4Q3I A;  4U08 A;  5GMH A;  2Z7X B;  3WPF A;  2V9S A;  4NKG A;  3M18 A;  4R5D A; 
#chains in the Genus database with same CATH homology
 4NKH A;  4CC4 C;  2OMW A;  4Z61 C;  4LSX A;  2OMT A;  3ULU A;  4PKI G;  4FDW A;  4Q3G A;  3RFS A;  5GQR K;  1D0B A;  1OTM A;  4L3A A;  3RGX A;  4TZH A;  2OMU A;  3GOZ A;  2WQV A;  4M7E A;  3W3L A;  5AWB A;  4KT1 A;  5GMF A;  4Y61 B;  4ARN A;  3JB9 j;  1A9N A;  3E3Z A;  4ECN A;  4XGO A;  4K17 A;  3W3N A;  5AWA A;  1O6V A;  1OTO A;  4Z8G A;  3FXI A;  4R6A A;  4R07 A;  4Z64 C;  4LSC A;  2P1O B;  4C2B B;  4QBZ A;  2R9U A;  1SQ0 B;  3M19 A;  4WP6 A;  1K5D C;  2P1P B;  4LSA A;  3O6N A;  2IFG A;  4FHO A;  4PQ8 A;  3G3B A;  3UL7 A;  3CIY A;  5B0T A;  4G8A A;  4P8S A;  3BZ5 A;  4I6J B;  2P1M B;  4WYK A;  4RCW A;  2WQW A;  3RFJ A;  2Q4G W;  1M0Z A;  1OGQ A;  2ELL A;  4LSX C;  3SB4 A;  2Y5Q A;  1KOO A;  2O6R A;  5AWC A;  4GT6 A;  3RJ0 A;  4R58 A;  1DFJ I;  5GMG A;  4P91 A;  3CIG A;  1OOK G;  5CMP A;  2Z82 A;  2UZX A;  1G9U A;  1FQV A;  4BSU A;  4LXS A;  4QC0 A;  3E2J A;  5A5C A;  1DCE A;  2WQX A;  5D3I A;  3RGZ A;  1O6T A;  3ULV A;  1H6U A;  4R09 A;  2JE1 A;  4FD0 A;  1XKU A;  2P1Q B;  4U7L A;  1PGV A;  3E4G A;  2RR6 A;  2Z7X A;  4H09 A;  3OGM B;  1GWB A;  3RIZ A;  1K5G C;  4R0A A;  1IO0 A;  4PSJ A;  3UL9 A;  1LTX A;  2BNH A;  5FTT B;  3PMH G;  1FS2 A;  4FCG A;  5IYX C;  3REZ A;  4BSR A;  3WPD A;  4BSS A;  1P8V A;  5LFN A;  2P1N B;  5AWD A;  3G06 A;  3OGK B;  1M9S A;  5IJC A;  1U0N D;  3WPG A;  5B0N A;  3TSR E;  3CVR A;  4V2D A;  1H6T A;  4R08 A;  3G3A A;  4V2C A;  3WPE A;  4CIL A;  2WQU A;  4HQ1 A;  1A4Y A;  2Z62 A;  2Z65 A;  3G39 A;  4RWT C;  4PEQ B;  4KXF B;  1FO1 A;  3W3J A;  3WPC A;  4U06 A;  2WFH A;  3WPH A;  5IJD A;  1XEC A;  2V70 A;  3ZYN A;  4GLP A;  1ZIW A;  4ECO A;  3G04 C;  4RCA B;  1Z7X W;  5HZL B;  3DZE A;  4M7E C;  4C2A B;  1M9L A;  4UFR A;  2FT3 A;  3RFE A;  3E6J A;  2A0Z A;  5HDH A;  3ZYO A;  4Z79 A;  4Z94 G;  3VQ2 A;  3UL8 A;  2CA6 A;  4L3F A;  2O6Q A;  1P8T A;  4LI2 A;  1W8A A;  2AST B;  5GS2 B;  1OZN A;  3UN9 A;  2Z63 A;  3P72 A;  5AZ5 A;  3WPI A;  4QXE A;  4CNM A;  3W3M A;  4LI1 A;  4B8C D;  5B4P A;  4U09 A;  1FT8 A;  1XWD C;  4R6J A;  2ASS B;  4YEB B;  1P9A G;  3ULA A;  5IJB A;  3OGL B;  2JE0 A;  2OMX A;  1OTN A;  4KNG A;  3RW6 A;  1JL5 A;  1WWL A;  1DS9 A;  2Z66 A;  3C6O B;  1O6S A;  4AY9 X;  4CC4 A;  1YRG A;  3ZYI A;  4PER A;  3KJ4 A;  3WN4 A;  4R6G A;  3ZYJ A;  4R5C A;  1QYY A;  4OQT A;  4XOS A;  4Q62 A;  4BV4 R;  1KOH A;  2UZY A;  5CMN A;  2XOT A;  4CP6 A;  2JQD A;  3C6P B;  2BEX A;  4LXR A;  4IM6 A;  2OMY A;  4ARR A;  3C6N B;  4CNC A;  4J4L A;  3VQ1 A;  4V2E A;  4R6F A;  2OMZ A;  3OJA B;  4MN8 B;  2O6S A;  1M10 B;  2V9T B;  3WPB A;  4XSQ A;  3W3K A;  4J0M A;  3O53 A;  3W3G A;  5GS0 A;  2ID5 A;  2Z81 A;  4FS7 A;  3A79 B;  4AW4 A;  2Z64 A;  4EZG A;  3RW7 A;  1XCD A;  3OJA A;  4FMZ A;  2RA8 A;  4MQW X;  2OMV A;  2XWT C;  1XEU A;  4Q3I A;  4U08 A;  5GMH A;  2Z7X B;  3WPF A;  2V9S A;  4NKG A;  3M18 A;  4R5D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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