5B0VA

Crystal structure of marburg virus vp40 dimer
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
266
structure length
258
Chain Sequence
GITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
pubmed doi rcsb
molecule tags Viral protein
source organism Lake victoria marburgvirus (strain musoke-80)
molecule keywords Matrix protein VP40
total genus 45
structure length 258
sequence length 266
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07447 VP40 Matrix protein VP40
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 5b0vA01
1H2CA 4LDMA 4LDDA 1H2DA 5B0VA 4LDBA 3TCQA 1ES6A 4LD8A
chains in the Genus database with same CATH superfamily
4G1OA 4LDMA 1CY7A 1H2DA 2O19A 1CY0A 1D6MA 3F1JA 2O5CA 4HI6A 4HITA 2VQPA 1ES6A 2O5EA 1H2CA 1ECLA 4HIUA 1CY6A 1MW9X 1CY8A 5D5HA 5B0VA 1I7DA 1CY4A 2O59A 4LDDA 1CYYA 1MW8X 4CHTA 2O54A 2GAJA 2GAIA 4HI5A 4LDBA 3TCQA 3PX7A 2YKDA 4V23A 3PWTA 4HIYA 4D4TA 1CY1A 4HIWA 1CY2A 4G1LA 4LP7A 4RULA 1CY9A 4LD8A 4G1GA 4CGYA
chains in the Genus database with same CATH topology
4G1OA 1H2DA 3F1JA 4HI6A 4HITA 2VQPA 1ES6A 1H2CA 4HIUA 5B0VA 4LDDA 4HI5A 4LDBA 3TCQA 4V23A 2YKDA 4HIYA 4D4TA 4HIWA 4G1LA 4LP7A 4LDMA 4LD8A 4G1GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H2C A;  4LDM A;  4LDD A;  1H2D A;  5B0V A;  4LDB A;  3TCQ A;  1ES6 A;  4LD8 A; 
#chains in the Genus database with same CATH topology
 4G1O A;  4LDM A;  1CY7 A;  1H2D A;  2O19 A;  1CY0 A;  1D6M A;  3F1J A;  2O5C A;  4HI6 A;  4HIT A;  2VQP A;  1ES6 A;  2O5E A;  1H2C A;  1ECL A;  4HIU A;  1CY6 A;  1MW9 X;  1CY8 A;  5D5H A;  5B0V A;  1I7D A;  1CY4 A;  2O59 A;  4LDD A;  1CYY A;  1MW8 X;  4CHT A;  2O54 A;  2GAJ A;  2GAI A;  4HI5 A;  4LDB A;  3TCQ A;  3PX7 A;  2YKD A;  4V23 A;  3PWT A;  4HIY A;  4D4T A;  1CY1 A;  4HIW A;  1CY2 A;  4G1L A;  4LP7 A;  4RUL A;  1CY9 A;  4LD8 A;  4G1G A;  4CGY A; 
#chains in the Genus database with same CATH homology
 4G1O A;  1H2D A;  3F1J A;  4HI6 A;  4HIT A;  2VQP A;  1ES6 A;  1H2C A;  4HIU A;  5B0V A;  4LDD A;  4HI5 A;  4LDB A;  3TCQ A;  4V23 A;  2YKD A;  4HIY A;  4D4T A;  4HIW A;  4G1L A;  4LP7 A;  4LDM A;  4LD8 A;  4G1G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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