5BP2A

Dehydratase domain (dh) of a mycocerosic acid synthase-like (mas-like) pks, crystal form 1
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
285
structure length
285
Chain Sequence
PSVSVHPLLGSHVVLPQEPEEHLWQGDVGTEAHPWLSDHRVHQVAVLPGAAYCEMALAAVTPVLGDTGEVHDLKFHDMLLLDDATPVWVSAAVTAPGTAEFGVETHQSGDRTQRATAVLRGDVDAERPAAHSIDALLAAHPNRVDGDELRAGFGTVGIGHGAAFAGLSEAYVATAAEPTVVAAVALPGPLRSGQRGYTVHPALLDACFQSVIAHPEVQNIASGMLLPLGVRRLRAYGSTRNVRYCLSRIVKADSFGVEADLELLDADGTVLLSAMGLQLGTGNSD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
pubmed doi rcsb
molecule tags Lyase
source organism Mycobacterium smegmatis
molecule keywords Mycocerosic acid synthase-like polyketide synthase
total genus 71
structure length 285
sequence length 285
chains with identical sequence B, C, D
ec nomenclature ec 2.3.1.-:
pdb deposition date 2015-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14765 PS-DH Polyketide synthase dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 5bp2A00
3KG7A 5BP3A 3HRRA 4LN9A 4OOCA 3KG9A 4U3VA 3HRQA 5E1VA 2VZ8A 5KKUA 3EL6A 5BP2A 3KG6A 4KC5A 2VZ9A
chains in the Genus database with same CATH superfamily
3KVIA 4HZNA 2EGIA 4A12A 1SC0A 3R32A 3KX8A 4U3VA 3SPSA 3P3IA 5EGJA 3KUVA 1SBKA 1IQ6A 5F6RA 1ZHGA 1WLUA 2XFLA 1LO8A 2GLMA 1LO7A 5EP5A 3LMBA 2QQPA 3F5OA 3ESIA 2O5UA 3R35A 4OOBA 3E8PA 4A0ZA 3NWZA 3LBEA 3CK1A 3DP2A 3TEAA 2V1OA 1WM6A 4I4JA 3KG9A 3R87A 3CF8A 3P2RA 3D6XA 2H4UA 3K67A 3ZH6A 2VZ9A 3ZH7A 4QDAA 4RLWA 3WEWA 2O6TA 3KV8A 4W78A 3ZH5A 4K4AA 5EGKA 3B7KA 4KEHA 5HD6A 3AZ8A 3HM0A 2C2IA 1IXLA 3KW1A 1WN3A 1Y7UA 4ORDA 1J1YA 2VKZG 1PSUA 4ZV3A 1PN2A 1PN4A 2F3XA 2OKIA 2PIMA 5EGLA 3AZAA 3ZH7B 4B0JA 3BBJA 5HWFA 5KKUA 4RLWB 1C8UA 2NUJA 3KX7A 4IENA 1NJKA 4W78B 3P3FA 1LO9A 3AZ9A 3Q62A 3HMJG 3R3CA 2FS2A 4K4CA 2CWZA 4HZPA 1Z54A 1BVQA 3B7JA 2OWNA 4I82A 3LW3A 3R37A 3FRNA 4M20A 4RV2B 4B0BA 1OHFA 1WLVA 4YBVA 1Q4SA 5HZ4A 3F1TA 3S6PA 4CL6A 3R3AA 2F0XA 3LBBA 2Q2BA 5E1VA 3D04A 4K02A 5BP3A 3D6LA 2HLJA 4WNBA 2CY9A 5SZZA 3DP0A 2F41A 5T07A 3R3DA 2PRXA 1Q4UA 2GF6A 2VZ8A 3DP1A 2B3MA 4B8UA 3HDUA 2EGRA 2FUJA 4QD9A 5EO2A 2OKHA 2GLVA 4QD8A 4XY5A 2PFCA 2OV9A 3KVZA 4MTUA 2DSLA 4WNBB 1TBUA 5SZYA 1YLIA 4RV2A 5SZUA 3EL6A 3KV7A 2UV8G 4I83A 4RLTA 4K49A 5BP2A 3E1EA 3LWGA 3BJKA 3OMLA 4K4DA 4KC5A 2Q78A 5HMCA 4B0CA 2O6UA 3HRRA 4RLJA 2GVHA 3DOYA 4ZRBA 4HZOA 4K00A 2QQ2A 2HX5A 5T02A 3KHPA 3U0AA 1T82A 3P2SA 4R4UA 3R3BA 3BNVA 2O6BA 1S5UA 3R34A 1U1ZA 5T06A 5BUYA 2OAFA 4GAKA 1S9CA 5DIOA 4FQ9A 4LN9A 4RLTB 3R3FA 3KUWA 4E3EA 1Q6WA 1VH9A 3E29A 4RLJB 2EISA 4RMMA 2B6EA 3KG6A 5EO4A 3AZBA 3KG8A 1MKBA 3CF9A 3P2QA 4H4GA 3RD7A 4A0YA 1Q4TA 4GAHA 4AE8A 5DM5A 4ZW0A 5SZVA 2QWZA 3B18A 1MKAA 3QOOA 1VI8A 3DOZA 2GLPA 1ZKIA 4FFUA 4OOCA 4RLUB 3EXZA 2OIWA 5BUXA 4QDBA 4XY6A 2XEMA 3KG7A 4NCPA 3DKZA 4QD7A 5CPGA 5HMBA 1YOCA 2CYEA 3QY3A 2GLLA 4I45A 1SH8A 3HRQA 2EGJA 3IR3A 4A0XA 4R9ZA 2HBOA 4AE7A 4B0IA 5BYUA 2AV9A 5KL9A 4K4BA 2BI0A 3ED0A 3KH8A 4MOBA 5BUWA 3S4KA 2PZHA 3KVUA 4MOCA 4RLUA 1Z6BA 1VH5A 4MZQA 3R36A 3RQBA 1VPMA 3CJYA 4QFWA 4ZJBA 4ZRFA 2ESSA 3GEKA 3DP3A 3LZ7A 2W3XA
chains in the Genus database with same CATH topology
2VKZG 4OOCA 2PFCA 3RQBA 4U3VA 3ZH7B 3BBJA 5KKUA 3EL6A 5BP2A 2UV8G 4KC5A 3KG7A 3HRRA 3HMJG 3U0AA 3HRQA 2QQPA 4R4UA 4R9ZA 3FRNA 1OHFA 4LN9A 3S6PA 3KG9A 5E1VA 3KG6A 3ZH6A 3ZH7A 2VZ9A 5BP3A 3KG8A 3RD7A 3CJYA 4QFWA 3ZH5A 2VZ8A 3B18A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KG7 A;  5BP3 A;  3HRR A;  4LN9 A;  4OOC A;  3KG9 A;  4U3V A;  3HRQ A;  5E1V A;  2VZ8 A;  5KKU A;  3EL6 A;  5BP2 A;  3KG6 A;  4KC5 A;  2VZ9 A; 
#chains in the Genus database with same CATH topology
 3KVI A;  4HZN A;  2EGI A;  4A12 A;  1SC0 A;  3R32 A;  3KX8 A;  4U3V A;  3SPS A;  3P3I A;  5EGJ A;  3KUV A;  1SBK A;  1IQ6 A;  5F6R A;  1ZHG A;  1WLU A;  2XFL A;  1LO8 A;  2GLM A;  1LO7 A;  5EP5 A;  3LMB A;  2QQP A;  3F5O A;  3ESI A;  2O5U A;  3R35 A;  4OOB A;  3E8P A;  4A0Z A;  3NWZ A;  3LBE A;  3CK1 A;  3DP2 A;  3TEA A;  2V1O A;  1WM6 A;  4I4J A;  3KG9 A;  3R87 A;  3CF8 A;  3P2R A;  3D6X A;  2H4U A;  3K67 A;  3ZH6 A;  2VZ9 A;  3ZH7 A;  4QDA A;  4RLW A;  3WEW A;  2O6T A;  3KV8 A;  4W78 A;  3ZH5 A;  4K4A A;  5EGK A;  3B7K A;  4KEH A;  5HD6 A;  3AZ8 A;  3HM0 A;  2C2I A;  1IXL A;  3KW1 A;  1WN3 A;  1Y7U A;  4ORD A;  1J1Y A;  2VKZ G;  1PSU A;  4ZV3 A;  1PN2 A;  1PN4 A;  2F3X A;  2OKI A;  2PIM A;  5EGL A;  3AZA A;  3ZH7 B;  4B0J A;  3BBJ A;  5HWF A;  5KKU A;  4RLW B;  1C8U A;  2NUJ A;  3KX7 A;  4IEN A;  1NJK A;  4W78 B;  3P3F A;  1LO9 A;  3AZ9 A;  3Q62 A;  3HMJ G;  3R3C A;  2FS2 A;  4K4C A;  2CWZ A;  4HZP A;  1Z54 A;  1BVQ A;  3B7J A;  2OWN A;  4I82 A;  3LW3 A;  3R37 A;  3FRN A;  4M20 A;  4RV2 B;  4B0B A;  1OHF A;  1WLV A;  4YBV A;  1Q4S A;  5HZ4 A;  3F1T A;  3S6P A;  4CL6 A;  3R3A A;  2F0X A;  3LBB A;  2Q2B A;  5E1V A;  3D04 A;  4K02 A;  5BP3 A;  3D6L A;  2HLJ A;  4WNB A;  2CY9 A;  5SZZ A;  3DP0 A;  2F41 A;  5T07 A;  3R3D A;  2PRX A;  1Q4U A;  2GF6 A;  2VZ8 A;  3DP1 A;  2B3M A;  4B8U A;  3HDU A;  2EGR A;  2FUJ A;  4QD9 A;  5EO2 A;  2OKH A;  2GLV A;  4QD8 A;  4XY5 A;  2PFC A;  2OV9 A;  3KVZ A;  4MTU A;  2DSL A;  4WNB B;  1TBU A;  5SZY A;  1YLI A;  4RV2 A;  5SZU A;  3EL6 A;  3KV7 A;  2UV8 G;  4I83 A;  4RLT A;  4K49 A;  5BP2 A;  3E1E A;  3LWG A;  3BJK A;  3OML A;  4K4D A;  4KC5 A;  2Q78 A;  5HMC A;  4B0C A;  2O6U A;  3HRR A;  4RLJ A;  2GVH A;  3DOY A;  4ZRB A;  4HZO A;  4K00 A;  2QQ2 A;  2HX5 A;  5T02 A;  3KHP A;  3U0A A;  1T82 A;  3P2S A;  4R4U A;  3R3B A;  3BNV A;  2O6B A;  1S5U A;  3R34 A;  1U1Z A;  5T06 A;  5BUY A;  2OAF A;  4GAK A;  1S9C A;  5DIO A;  4FQ9 A;  4LN9 A;  4RLT B;  3R3F A;  3KUW A;  4E3E A;  1Q6W A;  1VH9 A;  3E29 A;  4RLJ B;  2EIS A;  4RMM A;  2B6E A;  3KG6 A;  5EO4 A;  3AZB A;  3KG8 A;  1MKB A;  3CF9 A;  3P2Q A;  4H4G A;  3RD7 A;  4A0Y A;  1Q4T A;  4GAH A;  4AE8 A;  5DM5 A;  4ZW0 A;  5SZV A;  2QWZ A;  3B18 A;  1MKA A;  3QOO A;  1VI8 A;  3DOZ A;  2GLP A;  1ZKI A;  4FFU A;  4OOC A;  4RLU B;  3EXZ A;  2OIW A;  5BUX A;  4QDB A;  4XY6 A;  2XEM A;  3KG7 A;  4NCP A;  3DKZ A;  4QD7 A;  5CPG A;  5HMB A;  1YOC A;  2CYE A;  3QY3 A;  2GLL A;  4I45 A;  1SH8 A;  3HRQ A;  2EGJ A;  3IR3 A;  4A0X A;  4R9Z A;  2HBO A;  4AE7 A;  4B0I A;  5BYU A;  2AV9 A;  5KL9 A;  4K4B A;  2BI0 A;  3ED0 A;  3KH8 A;  4MOB A;  5BUW A;  3S4K A;  2PZH A;  3KVU A;  4MOC A;  4RLU A;  1Z6B A;  1VH5 A;  4MZQ A;  3R36 A;  3RQB A;  1VPM A;  3CJY A;  4QFW A;  4ZJB A;  4ZRF A;  2ESS A;  3GEK A;  3DP3 A;  3LZ7 A;  2W3X A; 
#chains in the Genus database with same CATH homology
 2VKZ G;  4OOC A;  2PFC A;  3RQB A;  4U3V A;  3ZH7 B;  3BBJ A;  5KKU A;  3EL6 A;  5BP2 A;  2UV8 G;  4KC5 A;  3KG7 A;  3HRR A;  3HMJ G;  3U0A A;  3HRQ A;  2QQP A;  4R4U A;  4R9Z A;  3FRN A;  1OHF A;  4LN9 A;  3S6P A;  3KG9 A;  5E1V A;  3KG6 A;  3ZH6 A;  3ZH7 A;  2VZ9 A;  5BP3 A;  3KG8 A;  3RD7 A;  3CJY A;  4QFW A;  3ZH5 A;  2VZ8 A;  3B18 A; 
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