5BTVA

Crystal structure of human 14-3-3 sigma in complex with a tau-protein peptide surrounding ps324
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
235
structure length
227
Chain Sequence
AMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSEERNLLSVAYKNVVGGQRAAWRVLSSIEQCSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords 14-3-3 protein sigma
total genus 101
structure length 227
sequence length 235
ec nomenclature
pdb deposition date 2015-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 5btvA00
5EWZA 4DX0A 5D3FA 4GNTA 1O9DA 1IB1A 4DAUA 2WH0A 3UALA 4ZDRA 1A37A 3P1SA 4O46A 2C74A 4DHSA 4ZQ0A 5BY9A 4DHPA 5EXAA 4FJ3A 4N7GA 4DHMA 3UZDA 3UX0A 5IQPA 1QJAA 2O8PA 5D3EA 3P1PA 4J6SA 4DATA 5J31A 4IEAA 3UBWA 3P1NA 4Y5IA 4JDDA 2BQ0A 4F7RA 4FR3A 4WRQA 5BTVA 4FL5A 5LU1A 4DHQA 2O98A 1QJBA 3SMOA 3M51A 5LHOA 3IQJA 3EFZA 3T0LA 4DHTA 3SMNA 2BR9A 4N84A 5D2DA 4E2EA 3LW1A 3IQUA 3SMLA 3RDHA 1O9CA 3U9XA 1O9FA 4JC3A 5F74A 3NKXA 3SPRA 3CU8A 1YZ5A 3M50A 4BG6A 4DNKA 2C1JA 1A38A 5LU2A 2BTPA 2V7DA 1YWTA 3E6YA 2O02A 4DHRA 4DHOA 2C23A 1O9EA 2B05A 2NPMA 4Y3BA 2C63A 3P1QA 4IHLA 3IQVA 4N7YA 3P1RA 5LX2A 3AXYC 4DHUA 3O8IA 3SMKA 3T0MA 5HF3A 4QLIA 1A4OA 4HKCA 2C1NA 3P1OA 3SMMA 5LVZA 3MHRA 3SP5A 4Y32A 4DHNA
chains in the Genus database with same CATH superfamily
5EWZA 4DX0A 4DHNA 1URJA 5D3FA 4GNTA 1O9DA 1IB1A 1DLCA 4DAUA 4QX0A 2WH0A 3UALA 4ZDRA 1A37A 3P1SA 4O46A 4QX3A 2C74A 4QX1A 4DHSA 4ZQ0A 5BY9A 4DHPA 3CQCA 5EXAA 4FJ3A 4N7GA 4DHMA 3UZDA 3UX0A 5IQPA 1QJAA 2O8PA 5D3EA 3P1PA 4J6SA 4DATA 5J31A 4IEAA 3UBWA 3P1NA 4Y5IA 4JDDA 2BQ0A 4QX2A 4FR3A 4WRQA 4F7RA 5BTVA 4FL5A 5LU1A 1CIYA 4DHQA 2O98A 1QJBA 3SMOA 3M51A 5LHOA 3IQJA 3EFZA 3CQGA 3T0LA 4DHTA 1JI6A 3SMNA 3X0UA 2BR9A 4N84A 5D2DA 4E2EA 3LW1A 3IQUA 3SMLA 3RDHA 1O9CA 3U9XA 1O9FA 4JC3A 1I5PA 5F74A 1W99A 3NKXA 3SPRA 3CU8A 1YZ5A 3M50A 4BG6A 4DNKA 2C1JA 4ARXA 1A38A 5LU2A 2BTPA 2C9KA 2V7DA 1YWTA 3E6YA 2O02A 4DHRA 4DHOA 4D8MA 2C23A 1O9EA 2B05A 2NPMA 4Y3BA 2C63A 3P1QA 4IHLA 3IQVA 4N7YA 4W8JA 3P1RA 5LX2A 3AXYC 4DHUA 4ARYA 3O8IA 3SMKA 3T0MA 5HF3A 1S2XA 3ZHEB 4QLIA 3I4RA 1A4OA 4HKCA 4MOAA 2C1NA 3P1OA 3SMMA 5LVZA 3MHRA 3SP5A 4Y32A 3EB7A
chains in the Genus database with same CATH topology
5EWZA 4DX0A 5D3FA 4GNTA 1O9DA 1IB1A 4DAUA 2WH0A 3UALA 4ZDRA 1A37A 3P1SA 4O46A 2C74A 4DHSA 4ZQ0A 5BY9A 4DHPA 5EXAA 4FJ3A 4N7GA 4DHMA 3UZDA 3UX0A 5IQPA 1QJAA 2O8PA 5D3EA 3P1PA 4J6SA 4DATA 5J31A 4IEAA 3UBWA 3P1NA 4Y5IA 4JDDA 2BQ0A 4F7RA 4FR3A 4WRQA 5BTVA 4FL5A 5LU1A 4DHQA 2O98A 1QJBA 3SMOA 3M51A 5LHOA 3IQJA 3EFZA 3T0LA 4DHTA 3SMNA 2BR9A 4N84A 5D2DA 4E2EA 3LW1A 3IQUA 3SMLA 3RDHA 1O9CA 3U9XA 1O9FA 4JC3A 5F74A 3NKXA 3SPRA 3CU8A 1YZ5A 3M50A 4BG6A 4DNKA 2C1JA 1A38A 5LU2A 2BTPA 2V7DA 1YWTA 3E6YA 2O02A 4DHRA 4DHOA 2C23A 1O9EA 2B05A 2NPMA 4Y3BA 2C63A 3P1QA 4IHLA 3IQVA 4N7YA 3P1RA 5LX2A 3AXYC 4DHUA 3O8IA 3SMKA 3T0MA 5HF3A 4QLIA 1A4OA 4HKCA 2C1NA 3P1OA 3SMMA 5LVZA 3MHRA 3SP5A 4Y32A 4DHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EWZ A;  4DX0 A;  5D3F A;  4GNT A;  1O9D A;  1IB1 A;  4DAU A;  2WH0 A;  3UAL A;  4ZDR A;  1A37 A;  3P1S A;  4O46 A;  2C74 A;  4DHS A;  4ZQ0 A;  5BY9 A;  4DHP A;  5EXA A;  4FJ3 A;  4N7G A;  4DHM A;  3UZD A;  3UX0 A;  5IQP A;  1QJA A;  2O8P A;  5D3E A;  3P1P A;  4J6S A;  4DAT A;  5J31 A;  4IEA A;  3UBW A;  3P1N A;  4Y5I A;  4JDD A;  2BQ0 A;  4F7R A;  4FR3 A;  4WRQ A;  5BTV A;  4FL5 A;  5LU1 A;  4DHQ A;  2O98 A;  1QJB A;  3SMO A;  3M51 A;  5LHO A;  3IQJ A;  3EFZ A;  3T0L A;  4DHT A;  3SMN A;  2BR9 A;  4N84 A;  5D2D A;  4E2E A;  3LW1 A;  3IQU A;  3SML A;  3RDH A;  1O9C A;  3U9X A;  1O9F A;  4JC3 A;  5F74 A;  3NKX A;  3SPR A;  3CU8 A;  1YZ5 A;  3M50 A;  4BG6 A;  4DNK A;  2C1J A;  1A38 A;  5LU2 A;  2BTP A;  2V7D A;  1YWT A;  3E6Y A;  2O02 A;  4DHR A;  4DHO A;  2C23 A;  1O9E A;  2B05 A;  2NPM A;  4Y3B A;  2C63 A;  3P1Q A;  4IHL A;  3IQV A;  4N7Y A;  3P1R A;  5LX2 A;  3AXY C;  4DHU A;  3O8I A;  3SMK A;  3T0M A;  5HF3 A;  4QLI A;  1A4O A;  4HKC A;  2C1N A;  3P1O A;  3SMM A;  5LVZ A;  3MHR A;  3SP5 A;  4Y32 A;  4DHN A; 
#chains in the Genus database with same CATH topology
 5EWZ A;  4DX0 A;  4DHN A;  1URJ A;  5D3F A;  4GNT A;  1O9D A;  1IB1 A;  1DLC A;  4DAU A;  4QX0 A;  2WH0 A;  3UAL A;  4ZDR A;  1A37 A;  3P1S A;  4O46 A;  4QX3 A;  2C74 A;  4QX1 A;  4DHS A;  4ZQ0 A;  5BY9 A;  4DHP A;  3CQC A;  5EXA A;  4FJ3 A;  4N7G A;  4DHM A;  3UZD A;  3UX0 A;  5IQP A;  1QJA A;  2O8P A;  5D3E A;  3P1P A;  4J6S A;  4DAT A;  5J31 A;  4IEA A;  3UBW A;  3P1N A;  4Y5I A;  4JDD A;  2BQ0 A;  4QX2 A;  4FR3 A;  4WRQ A;  4F7R A;  5BTV A;  4FL5 A;  5LU1 A;  1CIY A;  4DHQ A;  2O98 A;  1QJB A;  3SMO A;  3M51 A;  5LHO A;  3IQJ A;  3EFZ A;  3CQG A;  3T0L A;  4DHT A;  1JI6 A;  3SMN A;  3X0U A;  2BR9 A;  4N84 A;  5D2D A;  4E2E A;  3LW1 A;  3IQU A;  3SML A;  3RDH A;  1O9C A;  3U9X A;  1O9F A;  4JC3 A;  1I5P A;  5F74 A;  1W99 A;  3NKX A;  3SPR A;  3CU8 A;  1YZ5 A;  3M50 A;  4BG6 A;  4DNK A;  2C1J A;  4ARX A;  1A38 A;  5LU2 A;  2BTP A;  2C9K A;  2V7D A;  1YWT A;  3E6Y A;  2O02 A;  4DHR A;  4DHO A;  4D8M A;  2C23 A;  1O9E A;  2B05 A;  2NPM A;  4Y3B A;  2C63 A;  3P1Q A;  4IHL A;  3IQV A;  4N7Y A;  4W8J A;  3P1R A;  5LX2 A;  3AXY C;  4DHU A;  4ARY A;  3O8I A;  3SMK A;  3T0M A;  5HF3 A;  1S2X A;  3ZHE B;  4QLI A;  3I4R A;  1A4O A;  4HKC A;  4MOA A;  2C1N A;  3P1O A;  3SMM A;  5LVZ A;  3MHR A;  3SP5 A;  4Y32 A;  3EB7 A; 
#chains in the Genus database with same CATH homology
 5EWZ A;  4DX0 A;  5D3F A;  4GNT A;  1O9D A;  1IB1 A;  4DAU A;  2WH0 A;  3UAL A;  4ZDR A;  1A37 A;  3P1S A;  4O46 A;  2C74 A;  4DHS A;  4ZQ0 A;  5BY9 A;  4DHP A;  5EXA A;  4FJ3 A;  4N7G A;  4DHM A;  3UZD A;  3UX0 A;  5IQP A;  1QJA A;  2O8P A;  5D3E A;  3P1P A;  4J6S A;  4DAT A;  5J31 A;  4IEA A;  3UBW A;  3P1N A;  4Y5I A;  4JDD A;  2BQ0 A;  4F7R A;  4FR3 A;  4WRQ A;  5BTV A;  4FL5 A;  5LU1 A;  4DHQ A;  2O98 A;  1QJB A;  3SMO A;  3M51 A;  5LHO A;  3IQJ A;  3EFZ A;  3T0L A;  4DHT A;  3SMN A;  2BR9 A;  4N84 A;  5D2D A;  4E2E A;  3LW1 A;  3IQU A;  3SML A;  3RDH A;  1O9C A;  3U9X A;  1O9F A;  4JC3 A;  5F74 A;  3NKX A;  3SPR A;  3CU8 A;  1YZ5 A;  3M50 A;  4BG6 A;  4DNK A;  2C1J A;  1A38 A;  5LU2 A;  2BTP A;  2V7D A;  1YWT A;  3E6Y A;  2O02 A;  4DHR A;  4DHO A;  2C23 A;  1O9E A;  2B05 A;  2NPM A;  4Y3B A;  2C63 A;  3P1Q A;  4IHL A;  3IQV A;  4N7Y A;  3P1R A;  5LX2 A;  3AXY C;  4DHU A;  3O8I A;  3SMK A;  3T0M A;  5HF3 A;  4QLI A;  1A4O A;  4HKC A;  2C1N A;  3P1O A;  3SMM A;  5LVZ A;  3MHR A;  3SP5 A;  4Y32 A;  4DHN A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...