5C2TD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with rhodoquinone-2
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
pubmed doi rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 44
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 5c2tD00
4YSXC 3VRBD 1ZOYD 3AE1C 3CIRC 1KFYD 2H88C 3AE7C 3AE9D 3AEGD 2WP9D 2B76D 1YQ4D 3AE5C 2ACZD 5C3JC 2WDQD 3P4PD 3AEBC 3SFED 1L0VC 2BS3C 2WQYC 2WDRC 4YTND 3VR9D 4YTPD 2WU5C 3P4QC 3AECD 3ABVC 2H89D 2WU2C 4KX6D 5C2TD 3AEFC 4YSYD 1KF6C 3AEAC 2WDVC 2BS4C 4YXDC 1NEKC 3SFDC 1NEND 3VRAC 4YTMC 1ZP0D 3AEEC 3AE3C 4YSZD 3P4SC 2FBWC 3VR8D 2BS2C 4YSXD 2WS3C 3P4RC 3AE1D 3CIRD 2H88D 3AE7D 1YQ3C 3AEDC 3AE8C 3AE4C 3AE5D 3AE6C 5C3JD 4YT0D 3AEBD 1KFYC 3AE2C 1L0VD 2WQYD 2WDRD 3VRBC 1ZOYC 3AE9C 2WU5D 3AEGC 2WP9C 3P4QD 2B76C 1YQ4C 3ABVD 2ACZC 2WU2D 3AEFD 2WDQC 1KF6D 3P4PC 3AEAD 2WDVD 4YXDD 3SFEC 1NEKD 3SFDD 4YTNC 4YTMD 3VRAD 3AE3D 3AEED 3VR9C 3P4SD 4YTPC 2FBWD 3AECC 2H89C 5C2TC 4KX6C 4YT0C 1QLBC 2WS3D 4YSYC 3P4RD 1YQ3D 1E7PC 1NENC 3AEDD 1ZP0C 3AE8D 4YSZC 3AE4D 3VR8C 3AE6D 3AE2D
chains in the Genus database with same CATH superfamily
4YSXC 3VRBD 1ZOYD 3AE1C 3CIRC 1KFYD 2H88C 3AE7C 3AE9D 3AEGD 2WP9D 2B76D 1YQ4D 3AE5C 2ACZD 5C3JC 2WDQD 3P4PD 3AEBC 3SFED 1L0VC 2BS3C 2WQYC 2WDRC 4YTND 3VR9D 4YTPD 2WU5C 4LDTA 3P4QC 3AECD 3ABVC 2H89D 2WU2C 4KX6D 5C2TD 3AEFC 4YSYD 1KF6C 3AEAC 2WDVC 2BS4C 4YXDC 1NEKC 3SFDC 1NEND 3VRAC 4YTMC 1ZP0D 3AEEC 3AE3C 4YSZD 3P4SC 2FBWC 3VR8D 2BS2C 1TFFA 4DDIA 2WS3C 4YSXD 3P4RC 3AE1D 3CIRD 2H88D 3AE7D 1YQ3C 3AEDC 2ZFYA 3AE8C 3AE4C 3AE5D 3AE6C 4I6LA 5C3JD 4YT0D 3AEBD 1KFYC 3AE2C 1L0VD 2WQYD 2WDRD 3VRBC 1ZOYC 3AE9C 2WU5D 3AEGC 2WP9C 3P4QD 2B76C 4DHJA 1YQ4C 4DHZA 3ABVD 2ACZC 2WU2D 3AEFD 2WDQC 1KF6D 3P4PC 3AEAD 2WDVD 4DDGA 4YXDD 3SFEC 4FJVA 1NEKD 3SFDD 4YTNC 4YTMD 3VRAD 3AE3D 3AEED 3VR9C 3P4SD 4YTPC 2FBWD 3AECC 2H89C 5C2TC 4KX6C 4YT0C 1QLBC 2WS3D 4YSYC 3P4RD 1YQ3D 1E7PC 1NENC 3AEDD 1ZP0C 3AE8D 4YSZC 3AE4D 3VR8C 3AE6D 3VONA 3AE2D 4DHIB
chains in the Genus database with same CATH topology
4YSXC 3VRBD 1ZOYD 3AE1C 3CIRC 1KFYD 2H88C 3AE7C 3AE9D 3AEGD 2WP9D 2B76D 1YQ4D 3AE5C 2ACZD 5C3JC 2WDQD 3P4PD 3AEBC 3SFED 1L0VC 2BS3C 2WQYC 2WDRC 4YTND 3VR9D 4YTPD 2WU5C 3P4QC 3AECD 3ABVC 2H89D 2WU2C 4KX6D 5C2TD 3AEFC 4YSYD 1KF6C 3AEAC 2WDVC 2BS4C 4YXDC 1NEKC 3SFDC 1NEND 3VRAC 4YTMC 1ZP0D 3AEEC 3AE3C 4YSZD 3P4SC 2FBWC 3VR8D 2BS2C 4YSXD 2WS3C 3P4RC 3AE1D 3CIRD 2H88D 3AE7D 1YQ3C 3AEDC 3AE8C 3AE4C 3AE5D 3AE6C 5C3JD 4YT0D 3AEBD 1KFYC 3AE2C 1L0VD 2WQYD 2WDRD 3VRBC 1ZOYC 3AE9C 2WU5D 3AEGC 2WP9C 3P4QD 2B76C 1YQ4C 3ABVD 2ACZC 2WU2D 3AEFD 2WDQC 1KF6D 3P4PC 3AEAD 2WDVD 4YXDD 3SFEC 1NEKD 3SFDD 4YTNC 4YTMD 3VRAD 3AE3D 3AEED 3VR9C 3P4SD 4YTPC 2FBWD 3AECC 2H89C 5C2TC 4KX6C 4YT0C 1QLBC 2WS3D 4YSYC 3P4RD 1YQ3D 1E7PC 1NENC 3AEDD 1ZP0C 3AE8D 4YSZC 3AE4D 3VR8C 3AE6D 3AE2D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YSX C;  3VRB D;  1ZOY D;  3AE1 C;  3CIR C;  1KFY D;  2H88 C;  3AE7 C;  3AE9 D;  3AEG D;  2WP9 D;  2B76 D;  1YQ4 D;  3AE5 C;  2ACZ D;  5C3J C;  2WDQ D;  3P4P D;  3AEB C;  3SFE D;  1L0V C;  2BS3 C;  2WQY C;  2WDR C;  4YTN D;  3VR9 D;  4YTP D;  2WU5 C;  3P4Q C;  3AEC D;  3ABV C;  2H89 D;  2WU2 C;  4KX6 D;  5C2T D;  3AEF C;  4YSY D;  1KF6 C;  3AEA C;  2WDV C;  2BS4 C;  4YXD C;  1NEK C;  3SFD C;  1NEN D;  3VRA C;  4YTM C;  1ZP0 D;  3AEE C;  3AE3 C;  4YSZ D;  3P4S C;  2FBW C;  3VR8 D;  2BS2 C;  4YSX D;  2WS3 C;  3P4R C;  3AE1 D;  3CIR D;  2H88 D;  3AE7 D;  1YQ3 C;  3AED C;  3AE8 C;  3AE4 C;  3AE5 D;  3AE6 C;  5C3J D;  4YT0 D;  3AEB D;  1KFY C;  3AE2 C;  1L0V D;  2WQY D;  2WDR D;  3VRB C;  1ZOY C;  3AE9 C;  2WU5 D;  3AEG C;  2WP9 C;  3P4Q D;  2B76 C;  1YQ4 C;  3ABV D;  2ACZ C;  2WU2 D;  3AEF D;  2WDQ C;  1KF6 D;  3P4P C;  3AEA D;  2WDV D;  4YXD D;  3SFE C;  1NEK D;  3SFD D;  4YTN C;  4YTM D;  3VRA D;  3AE3 D;  3AEE D;  3VR9 C;  3P4S D;  4YTP C;  2FBW D;  3AEC C;  2H89 C;  5C2T C;  4KX6 C;  4YT0 C;  1QLB C;  2WS3 D;  4YSY C;  3P4R D;  1YQ3 D;  1E7P C;  1NEN C;  3AED D;  1ZP0 C;  3AE8 D;  4YSZ C;  3AE4 D;  3VR8 C;  3AE6 D;  3AE2 D; 
#chains in the Genus database with same CATH topology
 4YSX C;  3VRB D;  1ZOY D;  3AE1 C;  3CIR C;  1KFY D;  2H88 C;  3AE7 C;  3AE9 D;  3AEG D;  2WP9 D;  2B76 D;  1YQ4 D;  3AE5 C;  2ACZ D;  5C3J C;  2WDQ D;  3P4P D;  3AEB C;  3SFE D;  1L0V C;  2BS3 C;  2WQY C;  2WDR C;  4YTN D;  3VR9 D;  4YTP D;  2WU5 C;  4LDT A;  3P4Q C;  3AEC D;  3ABV C;  2H89 D;  2WU2 C;  4KX6 D;  5C2T D;  3AEF C;  4YSY D;  1KF6 C;  3AEA C;  2WDV C;  2BS4 C;  4YXD C;  1NEK C;  3SFD C;  1NEN D;  3VRA C;  4YTM C;  1ZP0 D;  3AEE C;  3AE3 C;  4YSZ D;  3P4S C;  2FBW C;  3VR8 D;  2BS2 C;  1TFF A;  4DDI A;  2WS3 C;  4YSX D;  3P4R C;  3AE1 D;  3CIR D;  2H88 D;  3AE7 D;  1YQ3 C;  3AED C;  2ZFY A;  3AE8 C;  3AE4 C;  3AE5 D;  3AE6 C;  4I6L A;  5C3J D;  4YT0 D;  3AEB D;  1KFY C;  3AE2 C;  1L0V D;  2WQY D;  2WDR D;  3VRB C;  1ZOY C;  3AE9 C;  2WU5 D;  3AEG C;  2WP9 C;  3P4Q D;  2B76 C;  4DHJ A;  1YQ4 C;  4DHZ A;  3ABV D;  2ACZ C;  2WU2 D;  3AEF D;  2WDQ C;  1KF6 D;  3P4P C;  3AEA D;  2WDV D;  4DDG A;  4YXD D;  3SFE C;  4FJV A;  1NEK D;  3SFD D;  4YTN C;  4YTM D;  3VRA D;  3AE3 D;  3AEE D;  3VR9 C;  3P4S D;  4YTP C;  2FBW D;  3AEC C;  2H89 C;  5C2T C;  4KX6 C;  4YT0 C;  1QLB C;  2WS3 D;  4YSY C;  3P4R D;  1YQ3 D;  1E7P C;  1NEN C;  3AED D;  1ZP0 C;  3AE8 D;  4YSZ C;  3AE4 D;  3VR8 C;  3AE6 D;  3VON A;  3AE2 D;  4DHI B; 
#chains in the Genus database with same CATH homology
 4YSX C;  3VRB D;  1ZOY D;  3AE1 C;  3CIR C;  1KFY D;  2H88 C;  3AE7 C;  3AE9 D;  3AEG D;  2WP9 D;  2B76 D;  1YQ4 D;  3AE5 C;  2ACZ D;  5C3J C;  2WDQ D;  3P4P D;  3AEB C;  3SFE D;  1L0V C;  2BS3 C;  2WQY C;  2WDR C;  4YTN D;  3VR9 D;  4YTP D;  2WU5 C;  3P4Q C;  3AEC D;  3ABV C;  2H89 D;  2WU2 C;  4KX6 D;  5C2T D;  3AEF C;  4YSY D;  1KF6 C;  3AEA C;  2WDV C;  2BS4 C;  4YXD C;  1NEK C;  3SFD C;  1NEN D;  3VRA C;  4YTM C;  1ZP0 D;  3AEE C;  3AE3 C;  4YSZ D;  3P4S C;  2FBW C;  3VR8 D;  2BS2 C;  4YSX D;  2WS3 C;  3P4R C;  3AE1 D;  3CIR D;  2H88 D;  3AE7 D;  1YQ3 C;  3AED C;  3AE8 C;  3AE4 C;  3AE5 D;  3AE6 C;  5C3J D;  4YT0 D;  3AEB D;  1KFY C;  3AE2 C;  1L0V D;  2WQY D;  2WDR D;  3VRB C;  1ZOY C;  3AE9 C;  2WU5 D;  3AEG C;  2WP9 C;  3P4Q D;  2B76 C;  1YQ4 C;  3ABV D;  2ACZ C;  2WU2 D;  3AEF D;  2WDQ C;  1KF6 D;  3P4P C;  3AEA D;  2WDV D;  4YXD D;  3SFE C;  1NEK D;  3SFD D;  4YTN C;  4YTM D;  3VRA D;  3AE3 D;  3AEE D;  3VR9 C;  3P4S D;  4YTP C;  2FBW D;  3AEC C;  2H89 C;  5C2T C;  4KX6 C;  4YT0 C;  1QLB C;  2WS3 D;  4YSY C;  3P4R D;  1YQ3 D;  1E7P C;  1NEN C;  3AED D;  1ZP0 C;  3AE8 D;  4YSZ C;  3AE4 D;  3VR8 C;  3AE6 D;  3AE2 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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