5C3JD

Crystal structure of mitochondrial rhodoquinol-fumarate reductase from ascaris suum with ubiquinone-1
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
129
structure length
129
Chain Sequence
TSAAVTGAAPPQFDPIAAEKGFKPLHSHGTLFKIERYFAAAMVPLIPAAYFIHGREMDLCLALALTLHVHWGVWGVVNDYGRPFVLGDTLAAAVRVGAYIFTACLLAGLLYFNEHDVGLTRAFEMVWEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria
rcsb
molecule tags Oxidoreductase/oxidoreductase inhibitor
molecule keywords Succinate dehydrogenase [ubiquinone] flavoprotein subunit, m
total genus 37
structure length 129
sequence length 129
chains with identical sequence H
ec nomenclature
pdb deposition date 2015-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF05328 CybS CybS, succinate dehydrogenase cytochrome B small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1300.10 Mainly Alpha Up-down Bundle 3 helical TM bundles of succinate and fumarate reductases Fumarate reductase/succinate dehydrogenase, transmembrane subunit 5c3jD00
3ABVD 3AE8C 2BS4C 1NEND 2WQYC 1ZOYC 2H89C 4YT0D 2BS2C 3AE8D 2WQYD 1ZOYD 2H89D 3AE5C 3SFED 2WS3C 1E7PC 3AE5D 1KFYC 2WS3D 1QLBC 2WDRC 4KX6C 5C2TD 1KFYD 1L0VC 2WDRD 4KX6D 2WP9D 3AE6C 1L0VD 3SFDC 3ABVC 1ZP0C 3AE6D 3SFDD 3VRAC 3AEEC 3AE3C 1ZP0D 3SFEC 3VRAD 3P4SC 3AEED 3AE3D 3P4QD 4YTMD 3P4PC 3AECC 2BS3C 3CIRC 2WP9C 4YXDC 2WDVC 3P4PD 3AECD 3AE4D 3CIRD 2WDQD 4YXDD 3AE2C 3AE1C 2WDVD 1YQ4C 3AE2D 3AE1D 3AEGD 1YQ3C 3VR9C 1YQ4D 3AEDC 3P4QC 3VR8C 2WU2C 1YQ3D 4YTMC 3VR9D 3AEDD 3VR8D 2WU2D 3AE7D 1NEKC 2ACZC 2H88D 3AEFC 5C3JD 1NEKD 2WU5C 2ACZD 3AE4C 3AE9D 2WDQC 3AEFD 2WU5D 3AEGC 3P4SD 3AEAC 1KF6C 4YTPC 2B76C 2FBWC 3AEAD 1KF6D 4YTPD 2B76D 3P4RC 2FBWD 4YSXC 3VRBC 3AEBC 3AE7C 4YSYC 3P4RD 2H88C 3VRBD 4YSXD 3AEBD 4YTNC 5C3JC 4YSYD 3AE9C 4YTND 5C2TC 4YSZC 1NENC 4YT0C 4YSZD
chains in the Genus database with same CATH superfamily
3ABVD 3AE8C 2BS4C 1NEND 2WQYC 1ZOYC 2H89C 4YT0D 2BS2C 2ZFYA 3AE8D 2WQYD 4DHZA 1ZOYD 2H89D 3AE5C 3SFED 2WS3C 1E7PC 3AE5D 1TFFA 1KFYC 2WS3D 1QLBC 2WDRC 4KX6C 5C2TD 1KFYD 1L0VC 2WDRD 4I6LA 4KX6D 2WP9D 3AE6C 1L0VD 3SFDC 3ABVC 4DDGA 1ZP0C 3AE6D 3SFDD 3VRAC 4DDIA 3AEEC 3AE3C 1ZP0D 3SFEC 3VRAD 3P4SC 3AEED 3AE3D 3P4QD 4YTMD 3P4PC 3AECC 2BS3C 3CIRC 2WP9C 4YXDC 2WDVC 3P4PD 3AECD 3AE4D 3CIRD 2WDQD 4YXDD 3AE2C 3AE1C 2WDVD 1YQ4C 3AE2D 3AE1D 4LDTA 3AEGD 1YQ3C 3VR9C 1YQ4D 3AEDC 3P4QC 3VR8C 2WU2C 1YQ3D 4YTMC 3VR9D 3AEDD 3VR8D 2WU2D 4DHIB 3AE7D 1NEKC 2ACZC 2H88D 3AEFC 5C3JD 1NEKD 2WU5C 2ACZD 3AE4C 3AE9D 2WDQC 3AEFD 2WU5D 3AEGC 3P4SD 3AEAC 1KF6C 4YTPC 2B76C 2FBWC 3AEAD 4FJVA 1KF6D 4YTPD 2B76D 3P4RC 2FBWD 4YSXC 3VRBC 3AEBC 3AE7C 4YSYC 3P4RD 2H88C 3VRBD 4YSXD 3AEBD 4YTNC 3VONA 5C3JC 4YSYD 3AE9C 4YTND 5C2TC 4YSZC 1NENC 4YT0C 4DHJA 4YSZD
chains in the Genus database with same CATH topology
3ABVD 3AE8C 2BS4C 1NEND 2WQYC 1ZOYC 2H89C 4YT0D 2BS2C 3AE8D 2WQYD 1ZOYD 2H89D 3AE5C 3SFED 2WS3C 1E7PC 3AE5D 1KFYC 2WS3D 1QLBC 2WDRC 4KX6C 5C2TD 1KFYD 1L0VC 2WDRD 4KX6D 2WP9D 3AE6C 1L0VD 3SFDC 3ABVC 1ZP0C 3AE6D 3SFDD 3VRAC 3AEEC 3AE3C 1ZP0D 3SFEC 3VRAD 3P4SC 3AEED 3AE3D 3P4QD 4YTMD 3P4PC 3AECC 2BS3C 3CIRC 2WP9C 4YXDC 2WDVC 3P4PD 3AECD 3AE4D 3CIRD 2WDQD 4YXDD 3AE2C 3AE1C 2WDVD 1YQ4C 3AE2D 3AE1D 3AEGD 1YQ3C 3VR9C 1YQ4D 3AEDC 3P4QC 3VR8C 2WU2C 1YQ3D 4YTMC 3VR9D 3AEDD 3VR8D 2WU2D 3AE7D 1NEKC 2ACZC 2H88D 3AEFC 5C3JD 1NEKD 2WU5C 2ACZD 3AE4C 3AE9D 2WDQC 3AEFD 2WU5D 3AEGC 3P4SD 3AEAC 1KF6C 4YTPC 2B76C 2FBWC 3AEAD 1KF6D 4YTPD 2B76D 3P4RC 2FBWD 4YSXC 3VRBC 3AEBC 3AE7C 4YSYC 3P4RD 2H88C 3VRBD 4YSXD 3AEBD 4YTNC 5C3JC 4YSYD 3AE9C 4YTND 5C2TC 4YSZC 1NENC 4YT0C 4YSZD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ABV D;  3AE8 C;  2BS4 C;  1NEN D;  2WQY C;  1ZOY C;  2H89 C;  4YT0 D;  2BS2 C;  3AE8 D;  2WQY D;  1ZOY D;  2H89 D;  3AE5 C;  3SFE D;  2WS3 C;  1E7P C;  3AE5 D;  1KFY C;  2WS3 D;  1QLB C;  2WDR C;  4KX6 C;  5C2T D;  1KFY D;  1L0V C;  2WDR D;  4KX6 D;  2WP9 D;  3AE6 C;  1L0V D;  3SFD C;  3ABV C;  1ZP0 C;  3AE6 D;  3SFD D;  3VRA C;  3AEE C;  3AE3 C;  1ZP0 D;  3SFE C;  3VRA D;  3P4S C;  3AEE D;  3AE3 D;  3P4Q D;  4YTM D;  3P4P C;  3AEC C;  2BS3 C;  3CIR C;  2WP9 C;  4YXD C;  2WDV C;  3P4P D;  3AEC D;  3AE4 D;  3CIR D;  2WDQ D;  4YXD D;  3AE2 C;  3AE1 C;  2WDV D;  1YQ4 C;  3AE2 D;  3AE1 D;  3AEG D;  1YQ3 C;  3VR9 C;  1YQ4 D;  3AED C;  3P4Q C;  3VR8 C;  2WU2 C;  1YQ3 D;  4YTM C;  3VR9 D;  3AED D;  3VR8 D;  2WU2 D;  3AE7 D;  1NEK C;  2ACZ C;  2H88 D;  3AEF C;  5C3J D;  1NEK D;  2WU5 C;  2ACZ D;  3AE4 C;  3AE9 D;  2WDQ C;  3AEF D;  2WU5 D;  3AEG C;  3P4S D;  3AEA C;  1KF6 C;  4YTP C;  2B76 C;  2FBW C;  3AEA D;  1KF6 D;  4YTP D;  2B76 D;  3P4R C;  2FBW D;  4YSX C;  3VRB C;  3AEB C;  3AE7 C;  4YSY C;  3P4R D;  2H88 C;  3VRB D;  4YSX D;  3AEB D;  4YTN C;  5C3J C;  4YSY D;  3AE9 C;  4YTN D;  5C2T C;  4YSZ C;  1NEN C;  4YT0 C;  4YSZ D; 
#chains in the Genus database with same CATH topology
 3ABV D;  3AE8 C;  2BS4 C;  1NEN D;  2WQY C;  1ZOY C;  2H89 C;  4YT0 D;  2BS2 C;  2ZFY A;  3AE8 D;  2WQY D;  4DHZ A;  1ZOY D;  2H89 D;  3AE5 C;  3SFE D;  2WS3 C;  1E7P C;  3AE5 D;  1TFF A;  1KFY C;  2WS3 D;  1QLB C;  2WDR C;  4KX6 C;  5C2T D;  1KFY D;  1L0V C;  2WDR D;  4I6L A;  4KX6 D;  2WP9 D;  3AE6 C;  1L0V D;  3SFD C;  3ABV C;  4DDG A;  1ZP0 C;  3AE6 D;  3SFD D;  3VRA C;  4DDI A;  3AEE C;  3AE3 C;  1ZP0 D;  3SFE C;  3VRA D;  3P4S C;  3AEE D;  3AE3 D;  3P4Q D;  4YTM D;  3P4P C;  3AEC C;  2BS3 C;  3CIR C;  2WP9 C;  4YXD C;  2WDV C;  3P4P D;  3AEC D;  3AE4 D;  3CIR D;  2WDQ D;  4YXD D;  3AE2 C;  3AE1 C;  2WDV D;  1YQ4 C;  3AE2 D;  3AE1 D;  4LDT A;  3AEG D;  1YQ3 C;  3VR9 C;  1YQ4 D;  3AED C;  3P4Q C;  3VR8 C;  2WU2 C;  1YQ3 D;  4YTM C;  3VR9 D;  3AED D;  3VR8 D;  2WU2 D;  4DHI B;  3AE7 D;  1NEK C;  2ACZ C;  2H88 D;  3AEF C;  5C3J D;  1NEK D;  2WU5 C;  2ACZ D;  3AE4 C;  3AE9 D;  2WDQ C;  3AEF D;  2WU5 D;  3AEG C;  3P4S D;  3AEA C;  1KF6 C;  4YTP C;  2B76 C;  2FBW C;  3AEA D;  4FJV A;  1KF6 D;  4YTP D;  2B76 D;  3P4R C;  2FBW D;  4YSX C;  3VRB C;  3AEB C;  3AE7 C;  4YSY C;  3P4R D;  2H88 C;  3VRB D;  4YSX D;  3AEB D;  4YTN C;  3VON A;  5C3J C;  4YSY D;  3AE9 C;  4YTN D;  5C2T C;  4YSZ C;  1NEN C;  4YT0 C;  4DHJ A;  4YSZ D; 
#chains in the Genus database with same CATH homology
 3ABV D;  3AE8 C;  2BS4 C;  1NEN D;  2WQY C;  1ZOY C;  2H89 C;  4YT0 D;  2BS2 C;  3AE8 D;  2WQY D;  1ZOY D;  2H89 D;  3AE5 C;  3SFE D;  2WS3 C;  1E7P C;  3AE5 D;  1KFY C;  2WS3 D;  1QLB C;  2WDR C;  4KX6 C;  5C2T D;  1KFY D;  1L0V C;  2WDR D;  4KX6 D;  2WP9 D;  3AE6 C;  1L0V D;  3SFD C;  3ABV C;  1ZP0 C;  3AE6 D;  3SFD D;  3VRA C;  3AEE C;  3AE3 C;  1ZP0 D;  3SFE C;  3VRA D;  3P4S C;  3AEE D;  3AE3 D;  3P4Q D;  4YTM D;  3P4P C;  3AEC C;  2BS3 C;  3CIR C;  2WP9 C;  4YXD C;  2WDV C;  3P4P D;  3AEC D;  3AE4 D;  3CIR D;  2WDQ D;  4YXD D;  3AE2 C;  3AE1 C;  2WDV D;  1YQ4 C;  3AE2 D;  3AE1 D;  3AEG D;  1YQ3 C;  3VR9 C;  1YQ4 D;  3AED C;  3P4Q C;  3VR8 C;  2WU2 C;  1YQ3 D;  4YTM C;  3VR9 D;  3AED D;  3VR8 D;  2WU2 D;  3AE7 D;  1NEK C;  2ACZ C;  2H88 D;  3AEF C;  5C3J D;  1NEK D;  2WU5 C;  2ACZ D;  3AE4 C;  3AE9 D;  2WDQ C;  3AEF D;  2WU5 D;  3AEG C;  3P4S D;  3AEA C;  1KF6 C;  4YTP C;  2B76 C;  2FBW C;  3AEA D;  1KF6 D;  4YTP D;  2B76 D;  3P4R C;  2FBW D;  4YSX C;  3VRB C;  3AEB C;  3AE7 C;  4YSY C;  3P4R D;  2H88 C;  3VRB D;  4YSX D;  3AEB D;  4YTN C;  5C3J C;  4YSY D;  3AE9 C;  4YTN D;  5C2T C;  4YSZ C;  1NEN C;  4YT0 C;  4YSZ D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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