5C4XL

Crystal structure of a transcribing rna polymerase ii complex reveals a complete transcription bubble
Total Genus 3
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.
pubmed doi rcsb
molecule tags Transferase/rna/dna
source organism Saccharomyces cerevisiae (strain atcc 204508 / s288c)
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 3
structure length 44
sequence length 44
ec nomenclature
pdb deposition date 2015-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 5c4xL00
2JA7L 1K83L 4BBRL 2NVTL 3HOUL 3I4NL 4BXXL 3HOZL 1I50L 4C2M1 3S1QL 1I6HL 4A3LL 4QIWP 1SFOL 3PO2L 3H0GL 2E2JL 5C44L 3GTOL 3HOVL 3CQZL 3H3VM 4C3IL 5M5YL 2E2IL 3S1ML 3S15L 5C4JL 4C3JL 3HOXL 3FKIL 2B63L 4A93L 3RZOL 3GTGL 4A3JL 2R7ZL 4BBSL 4A3BL 4Y52L 3GTQL 1TWGL 4Y7NL 5C4XL 4X6AL 2JA8L 3HOYL 4A3DL 1I3QL 5FLML 3S2HL 4BY7L 5M3ML 2YU9L 5M5WL 1Y1VL 2E2HL 4BY1L 4A3GL 3M4OL 1TWFL 3K7AL 5IYBL 4A3KL 2NVYL 3GTML 3S17L 1R9TL 5IYCL 3RZDL 5C3EL 5FJ8L 2R92L 2WB1P 3M3YL 2NVQL 3S2DL 3PO3L 3S16L 3GTKL 2NVXL 2WAQP 2R93L 4A3CL 3GTJL 3S1RL 1TWHL 2JA6L 1WCML 5M3FL 3GTPL 5M5XL 5IP9L 4A3EL 2VUML 4AYBP 2Y0SP 3HOWL 2JA5L 1Y1WL 3S14L 4A3FL 2PMZP 3S1NL 4A3IL 3HKZP 4C3HL 3I4ML 1TWAL 1TWCL 5IYDL 5IP7L 3GTLL 4A3ML
chains in the Genus database with same CATH superfamily
1YUZA 2NVTL 3HOZL 2E2JL 5C44L 2KKDA 2M4YA 1OWBA 1CAAA 3CQZL 2KN9A 3H3VM 2XJVA 2GMGA 4AI2A 3S15L 1VCXA 4C3JL 3KYUA 3HOXL 4A93L 1BQ8A 7RXNA 3GTQL 2B5ID 1B2OA 4A3DL 2XJQA 4BY7L 2V0EA 1S30A 3P2AA 2YU9L 4RXNA 1Y1VL 2E2HL 2V3BB 3M4OL 1TWFL 2RFKB 3RYGA 2NVYL 1OWCA 3S17L 2ERJA 3MPSA 3WWLA 2PPTA 5FJ8L 2NVQL 1NNQA 1ZRPA 2PYAA 2DSXA 1NXGA 1RDVA 1BQ9A 2BE5D 5EIOC 1B13A 5EINC 1S2ZA 4POGA 1VZIA 1SMWA 4UY81 2CKAA 1R0GA 5GAGc 2CR8A 5RXNA 2C6BA 3KYVA 3LPEB 2JI3A 2M6PA 2AUSB 2A68D 3PWFA 1TWCL 4AI3A 2K2DA 3GTLL 2ZIXA 4LHLA 1SMUA 2ERSA 2NYDA 4AR5A 3I4NL 4BXXL 1I50L 1NXEA 3S1QL 4A3LL 1B2JA 5GADc 3SS2A 1WJVA 3HOVL 3KYWA 1R0IA 2A69D 1IU5A 3NFPI 3LWPB 5C4JL 1YK5A 3PZAA 5MFZA 1DX8A 2B63L 3RZOL 2O5JD 2C6AA 2R7ZL 4XXBB 4A3BL 1PFWA 4Y52L 1RYQA 3PKIA 2JA8L 3HOYL 2QL0A 5K2ME 5FLML 3S2HL 4ME3A 2EY4E 5IYBL 5AI3A 1QYBA 3RZDL 1LTLA 5C3EL 4JAFA 2R92L 3H9BA 3M3YL 3IU3I 2APOB 3K35A 3GTKL 5DM71 2CKCA 4YWLA 2NVXL 4A3CL 1R0HA 2HR5A 5DM61 5AN9H 2PVEA 3QQCE 3KYXA 3RZ6A 3GTPL 3LWRB 1VZGA 5M5XL 1RDGA 2PVXA 2H12A 2XJTA 5IP9L 4A3EL 2V0FA 4V196 3A44A 1CADA 5GAEc 2JA5L 2Z3QB 3S14L 4A3FL 3HKZP 4C3HL 3I4ML 3QVDA 5IYDL 1C09A 5IP7L 5JVH1 2JA7L 2AYJA 1K83L 3LWQB 2JI2A 1T9PA 3RZTA 4BBRL 1BFYA 4K9FA 4C2M1 1I6HL 4QIWP 1SFOL 1YV1A 3H0GL 1JYBA 3MSUA 1ODHA 4AR3A 3HJWB 4AR6A 4C3IL 2XJPA 3FKIL 3GTGL 4A3JL 3H97A 4BBSL 5MGNA 4AHYA 1TWGL 5C4XL 4X6AL 4TVMA 3LWOB 1YK4A 1I3QL 1RYTA 1LKMA 5M5WL 3B0AB 2PSMC 3FDJA 4AI0A 2RDVA 1PFUA 3GTML 5MFPA 1R9TL 5IYCL 1IU6A 1S24A 2AQCA 2WB1P 3PL5A 5MF6A 3S2DL 3PKJA 1LKOA 1LKPA 2WAQP 4ZN3B 1IW7D 3S1RL 3WWNB 4AI1A 1RB9A 5MLC3 1WCML 5M3FL 3MQKB 4TPUA 1BRFA 2XJUA 2JI1A 5AI2A 4AYBP 4U671 2Y0SP 3H99A 8RXNA 1T9QA 3ZG6A 3HOWL 4XGHA 1E8JA 4E6YA 3HAXC 1IRNA 2PMZP 3S1NL 3LWVB 2XJRA 3VPBE 4A3IL 1FHMA 3J7Y1 1RWDA 1FHHA 3LNLA 1QQTA 3HOUL 2VL6A 3JR7A 3PO2L 1B71A 3GTOL 4WFN1 2M6OA 5JVG1 1PFVA 2XJSA 4AR4A 2MS3A 1DVBA 3HJYB 1IROA 5M5YL 3B08B 2E2IL 3S1ML 4GS7D 2A6HD 4POFA 4AHXA 6RXNA 1QCVA 4Y7NL 4G6BA 2J9UB 1SMMA 1YUXA 5M3ML 4BY1L 5IY0A 4A3GL 1H7VA 2Z3RB 5H1Sc 1T9OA 3P8BA 3K7AL 4A3KL 1R0FA 1Z92B 1PZXA 2L0ZA 4LHNA 1BE7A 3PO3L 2HVYC 3S16L 1P7PA 2R93L 3GTJL 4JAEA 2M4VA 4JAGA 2A6ED 1TWHL 2JA6L 4AHZA 3KYYA 4ZN1B 3H9CA 1VZHA 2LCQA 5GAHc 1R0JA 4B8CD 2VUML 3PIP1 4JADA 4AHWA 3PIO1 1Y1WL 4YWMA 1PFYA 1F4LA 1TWAL 3J7Z1 4A3ML
chains in the Genus database with same CATH topology
2JA7L 1K83L 4BBRL 2NVTL 3HOUL 3I4NL 4BXXL 3HOZL 1I50L 4C2M1 3S1QL 1I6HL 4A3LL 4QIWP 1SFOL 3PO2L 3H0GL 2E2JL 5C44L 3GTOL 3HOVL 3CQZL 3H3VM 4C3IL 5M5YL 2E2IL 3S1ML 3S15L 5C4JL 4C3JL 3HOXL 3FKIL 2B63L 4A93L 3RZOL 3GTGL 4A3JL 2R7ZL 4BBSL 4A3BL 4Y52L 3GTQL 1TWGL 4Y7NL 5C4XL 4X6AL 2JA8L 3HOYL 4A3DL 1I3QL 5FLML 3S2HL 4BY7L 5M3ML 2YU9L 5M5WL 1Y1VL 2E2HL 4BY1L 4A3GL 3M4OL 1TWFL 3K7AL 5IYBL 4A3KL 2NVYL 3GTML 3S17L 1R9TL 5IYCL 3RZDL 5C3EL 5FJ8L 2R92L 2WB1P 3M3YL 2NVQL 3S2DL 3PO3L 3S16L 3GTKL 2NVXL 2WAQP 2R93L 4A3CL 3GTJL 3S1RL 1TWHL 2JA6L 1WCML 5M3FL 3GTPL 5M5XL 5IP9L 4A3EL 2VUML 4AYBP 2Y0SP 3HOWL 2JA5L 1Y1WL 3S14L 4A3FL 2PMZP 3S1NL 4A3IL 3HKZP 4C3HL 3I4ML 1TWAL 1TWCL 5IYDL 5IP7L 3GTLL 4A3ML
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JA7 L;  1K83 L;  4BBR L;  2NVT L;  3HOU L;  3I4N L;  4BXX L;  3HOZ L;  1I50 L;  4C2M 1;  3S1Q L;  1I6H L;  4A3L L;  4QIW P;  1SFO L;  3PO2 L;  3H0G L;  2E2J L;  5C44 L;  3GTO L;  3HOV L;  3CQZ L;  3H3V M;  4C3I L;  5M5Y L;  2E2I L;  3S1M L;  3S15 L;  5C4J L;  4C3J L;  3HOX L;  3FKI L;  2B63 L;  4A93 L;  3RZO L;  3GTG L;  4A3J L;  2R7Z L;  4BBS L;  4A3B L;  4Y52 L;  3GTQ L;  1TWG L;  4Y7N L;  5C4X L;  4X6A L;  2JA8 L;  3HOY L;  4A3D L;  1I3Q L;  5FLM L;  3S2H L;  4BY7 L;  5M3M L;  2YU9 L;  5M5W L;  1Y1V L;  2E2H L;  4BY1 L;  4A3G L;  3M4O L;  1TWF L;  3K7A L;  5IYB L;  4A3K L;  2NVY L;  3GTM L;  3S17 L;  1R9T L;  5IYC L;  3RZD L;  5C3E L;  5FJ8 L;  2R92 L;  2WB1 P;  3M3Y L;  2NVQ L;  3S2D L;  3PO3 L;  3S16 L;  3GTK L;  2NVX L;  2WAQ P;  2R93 L;  4A3C L;  3GTJ L;  3S1R L;  1TWH L;  2JA6 L;  1WCM L;  5M3F L;  3GTP L;  5M5X L;  5IP9 L;  4A3E L;  2VUM L;  4AYB P;  2Y0S P;  3HOW L;  2JA5 L;  1Y1W L;  3S14 L;  4A3F L;  2PMZ P;  3S1N L;  4A3I L;  3HKZ P;  4C3H L;  3I4M L;  1TWA L;  1TWC L;  5IYD L;  5IP7 L;  3GTL L;  4A3M L; 
#chains in the Genus database with same CATH topology
 1YUZ A;  2NVT L;  3HOZ L;  2E2J L;  5C44 L;  2KKD A;  2M4Y A;  1OWB A;  1CAA A;  3CQZ L;  2KN9 A;  3H3V M;  2XJV A;  2GMG A;  4AI2 A;  3S15 L;  1VCX A;  4C3J L;  3KYU A;  3HOX L;  4A93 L;  1BQ8 A;  7RXN A;  3GTQ L;  2B5I D;  1B2O A;  4A3D L;  2XJQ A;  4BY7 L;  2V0E A;  1S30 A;  3P2A A;  2YU9 L;  4RXN A;  1Y1V L;  2E2H L;  2V3B B;  3M4O L;  1TWF L;  2RFK B;  3RYG A;  2NVY L;  1OWC A;  3S17 L;  2ERJ A;  3MPS A;  3WWL A;  2PPT A;  5FJ8 L;  2NVQ L;  1NNQ A;  1ZRP A;  2PYA A;  2DSX A;  1NXG A;  1RDV A;  1BQ9 A;  2BE5 D;  5EIO C;  1B13 A;  5EIN C;  1S2Z A;  4POG A;  1VZI A;  1SMW A;  4UY8 1;  2CKA A;  1R0G A;  5GAG c;  2CR8 A;  5RXN A;  2C6B A;  3KYV A;  3LPE B;  2JI3 A;  2M6P A;  2AUS B;  2A68 D;  3PWF A;  1TWC L;  4AI3 A;  2K2D A;  3GTL L;  2ZIX A;  4LHL A;  1SMU A;  2ERS A;  2NYD A;  4AR5 A;  3I4N L;  4BXX L;  1I50 L;  1NXE A;  3S1Q L;  4A3L L;  1B2J A;  5GAD c;  3SS2 A;  1WJV A;  3HOV L;  3KYW A;  1R0I A;  2A69 D;  1IU5 A;  3NFP I;  3LWP B;  5C4J L;  1YK5 A;  3PZA A;  5MFZ A;  1DX8 A;  2B63 L;  3RZO L;  2O5J D;  2C6A A;  2R7Z L;  4XXB B;  4A3B L;  1PFW A;  4Y52 L;  1RYQ A;  3PKI A;  2JA8 L;  3HOY L;  2QL0 A;  5K2M E;  5FLM L;  3S2H L;  4ME3 A;  2EY4 E;  5IYB L;  5AI3 A;  1QYB A;  3RZD L;  1LTL A;  5C3E L;  4JAF A;  2R92 L;  3H9B A;  3M3Y L;  3IU3 I;  2APO B;  3K35 A;  3GTK L;  5DM7 1;  2CKC A;  4YWL A;  2NVX L;  4A3C L;  1R0H A;  2HR5 A;  5DM6 1;  5AN9 H;  2PVE A;  3QQC E;  3KYX A;  3RZ6 A;  3GTP L;  3LWR B;  1VZG A;  5M5X L;  1RDG A;  2PVX A;  2H12 A;  2XJT A;  5IP9 L;  4A3E L;  2V0F A;  4V19 6;  3A44 A;  1CAD A;  5GAE c;  2JA5 L;  2Z3Q B;  3S14 L;  4A3F L;  3HKZ P;  4C3H L;  3I4M L;  3QVD A;  5IYD L;  1C09 A;  5IP7 L;  5JVH 1;  2JA7 L;  2AYJ A;  1K83 L;  3LWQ B;  2JI2 A;  1T9P A;  3RZT A;  4BBR L;  1BFY A;  4K9F A;  4C2M 1;  1I6H L;  4QIW P;  1SFO L;  1YV1 A;  3H0G L;  1JYB A;  3MSU A;  1ODH A;  4AR3 A;  3HJW B;  4AR6 A;  4C3I L;  2XJP A;  3FKI L;  3GTG L;  4A3J L;  3H97 A;  4BBS L;  5MGN A;  4AHY A;  1TWG L;  5C4X L;  4X6A L;  4TVM A;  3LWO B;  1YK4 A;  1I3Q L;  1RYT A;  1LKM A;  5M5W L;  3B0A B;  2PSM C;  3FDJ A;  4AI0 A;  2RDV A;  1PFU A;  3GTM L;  5MFP A;  1R9T L;  5IYC L;  1IU6 A;  1S24 A;  2AQC A;  2WB1 P;  3PL5 A;  5MF6 A;  3S2D L;  3PKJ A;  1LKO A;  1LKP A;  2WAQ P;  4ZN3 B;  1IW7 D;  3S1R L;  3WWN B;  4AI1 A;  1RB9 A;  5MLC 3;  1WCM L;  5M3F L;  3MQK B;  4TPU A;  1BRF A;  2XJU A;  2JI1 A;  5AI2 A;  4AYB P;  4U67 1;  2Y0S P;  3H99 A;  8RXN A;  1T9Q A;  3ZG6 A;  3HOW L;  4XGH A;  1E8J A;  4E6Y A;  3HAX C;  1IRN A;  2PMZ P;  3S1N L;  3LWV B;  2XJR A;  3VPB E;  4A3I L;  1FHM A;  3J7Y 1;  1RWD A;  1FHH A;  3LNL A;  1QQT A;  3HOU L;  2VL6 A;  3JR7 A;  3PO2 L;  1B71 A;  3GTO L;  4WFN 1;  2M6O A;  5JVG 1;  1PFV A;  2XJS A;  4AR4 A;  2MS3 A;  1DVB A;  3HJY B;  1IRO A;  5M5Y L;  3B08 B;  2E2I L;  3S1M L;  4GS7 D;  2A6H D;  4POF A;  4AHX A;  6RXN A;  1QCV A;  4Y7N L;  4G6B A;  2J9U B;  1SMM A;  1YUX A;  5M3M L;  4BY1 L;  5IY0 A;  4A3G L;  1H7V A;  2Z3R B;  5H1S c;  1T9O A;  3P8B A;  3K7A L;  4A3K L;  1R0F A;  1Z92 B;  1PZX A;  2L0Z A;  4LHN A;  1BE7 A;  3PO3 L;  2HVY C;  3S16 L;  1P7P A;  2R93 L;  3GTJ L;  4JAE A;  2M4V A;  4JAG A;  2A6E D;  1TWH L;  2JA6 L;  4AHZ A;  3KYY A;  4ZN1 B;  3H9C A;  1VZH A;  2LCQ A;  5GAH c;  1R0J A;  4B8C D;  2VUM L;  3PIP 1;  4JAD A;  4AHW A;  3PIO 1;  1Y1W L;  4YWM A;  1PFY A;  1F4L A;  1TWA L;  3J7Z 1;  4A3M L; 
#chains in the Genus database with same CATH homology
 2JA7 L;  1K83 L;  4BBR L;  2NVT L;  3HOU L;  3I4N L;  4BXX L;  3HOZ L;  1I50 L;  4C2M 1;  3S1Q L;  1I6H L;  4A3L L;  4QIW P;  1SFO L;  3PO2 L;  3H0G L;  2E2J L;  5C44 L;  3GTO L;  3HOV L;  3CQZ L;  3H3V M;  4C3I L;  5M5Y L;  2E2I L;  3S1M L;  3S15 L;  5C4J L;  4C3J L;  3HOX L;  3FKI L;  2B63 L;  4A93 L;  3RZO L;  3GTG L;  4A3J L;  2R7Z L;  4BBS L;  4A3B L;  4Y52 L;  3GTQ L;  1TWG L;  4Y7N L;  5C4X L;  4X6A L;  2JA8 L;  3HOY L;  4A3D L;  1I3Q L;  5FLM L;  3S2H L;  4BY7 L;  5M3M L;  2YU9 L;  5M5W L;  1Y1V L;  2E2H L;  4BY1 L;  4A3G L;  3M4O L;  1TWF L;  3K7A L;  5IYB L;  4A3K L;  2NVY L;  3GTM L;  3S17 L;  1R9T L;  5IYC L;  3RZD L;  5C3E L;  5FJ8 L;  2R92 L;  2WB1 P;  3M3Y L;  2NVQ L;  3S2D L;  3PO3 L;  3S16 L;  3GTK L;  2NVX L;  2WAQ P;  2R93 L;  4A3C L;  3GTJ L;  3S1R L;  1TWH L;  2JA6 L;  1WCM L;  5M3F L;  3GTP L;  5M5X L;  5IP9 L;  4A3E L;  2VUM L;  4AYB P;  2Y0S P;  3HOW L;  2JA5 L;  1Y1W L;  3S14 L;  4A3F L;  2PMZ P;  3S1N L;  4A3I L;  3HKZ P;  4C3H L;  3I4M L;  1TWA L;  1TWC L;  5IYD L;  5IP7 L;  3GTL L;  4A3M L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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