5CSCA

Structure of an open form of chicken heart citrate synthase at 2.8 angstroms resolution
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
433
structure length
429
Chain Sequence
ASSTNLKDVLAALIPKEQARIKTFRQQHGGTALGQITVDMSYGGMRGMKGLVYETSVLDPDEGIRFRGFSIPECQKLLPKGGGGEPLPEGLFWLLVTGQIPTGAQVSWLSKEWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAITALNSESNFARAYAEGILRTKYWEMVYESAMDLIAKLPCVAAKIYRNLYRAGSSIGAIDSKLDWSHNFTNMLGYTDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLSFAAAMNGLAGPLHGLANQEVLGWLAQLQKAAGADASLRDYIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPGDPMFKLVAQLYKIVPNVLLEQGAAANPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLAQLIWSRALGFPLERPKSMSTDGLIAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution
pubmed doi rcsb
molecule keywords CITRATE SYNTHASE
molecule tags Oxo-acid-lyase
source organism Gallus gallus
total genus 125
structure length 429
sequence length 433
ec nomenclature ec 2.3.3.1: Citrate (Si)-synthase.
pdb deposition date 1990-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00285 Citrate_synt Citrate synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.230.10 Mainly Alpha Orthogonal Bundle Cytochrome p450-Terp; domain 2 Cytochrome P450-Terp, domain 2 5cscA02
1.10.580.10 Mainly Alpha Orthogonal Bundle Citrate Synthase; domain 1 Citrate Synthase, domain 1 5cscA01
3HWKA 4CTSA 4TVMA 1VGMA 2H12A 4JAGA 1IXEA 4YBOA 4E6YA 4XGHA 2IBPA 1AL6A 1NXGA 1OWCA 1AMZA 2R9EA 1CSIA 2CTSA 1OWBA 5CSCA 4JADA 6CSCA 1A59A 1NXEA 1AJ8A 1CSCA 2C6XA 1IOMA 3ENJA 4JAEA 1CSHA 4JAFA 5CTSA 3TQGA 1O7XA 2P2WA 1CSRA 3CSCA 5CSCB 2R26A 1VGPA 1CTSA 3MSUA 3O8JA 4G6BA 4CSCA 2CSCA 2IFCA 6CTSA 1CSSA
chains in the Genus database with same CATH superfamily
3HWKA 4CTSA 4TVMA 1VGMA 2H12A 4JAGA 1IXEA 4YBOA 4E6YA 4XGHA 2IBPA 1AL6A 1NXGA 1OWCA 1AMZA 2R9EA 1CSIA 2CTSA 1OWBA 5CSCA 4JADA 6CSCA 1A59A 1NXEA 1AJ8A 1CSCA 2C6XA 1IOMA 3ENJA 4JAEA 1CSHA 4JAFA 5CTSA 3TQGA 1O7XA 2P2WA 1CSRA 3CSCA 5CSCB 2R26A 1VGPA 1CTSA 3MSUA 3O8JA 4G6BA 4CSCA 2CSCA 2IFCA 6CTSA 1CSSA
chains in the Genus database with same CATH topology
3HWKA 4CTSA 4TVMA 1VGMA 2H12A 4JAGA 1IXEA 4YBOA 4E6YA 4XGHA 2IBPA 1AL6A 1NXGA 1OWCA 1AMZA 2R9EA 1CSIA 2CTSA 1OWBA 5CSCA 4JADA 6CSCA 1A59A 1NXEA 1AJ8A 1CSCA 2C6XA 1IOMA 3ENJA 4JAEA 1CSHA 4JAFA 5CTSA 3TQGA 1O7XA 2P2WA 1CSRA 3CSCA 5CSCB 2R26A 1VGPA 1CTSA 3MSUA 3O8JA 4G6BA 4CSCA 2CSCA 2IFCA 6CTSA 1CSSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HWK A;  4CTS A;  4TVM A;  1VGM A;  2H12 A;  4JAG A;  1IXE A;  4YBO A;  4E6Y A;  4XGH A;  2IBP A;  1AL6 A;  1NXG A;  1OWC A;  1AMZ A;  2R9E A;  1CSI A;  2CTS A;  1OWB A;  5CSC A;  4JAD A;  6CSC A;  1A59 A;  1NXE A;  1AJ8 A;  1CSC A;  2C6X A;  1IOM A;  3ENJ A;  4JAE A;  1CSH A;  4JAF A;  5CTS A;  3TQG A;  1O7X A;  2P2W A;  1CSR A;  3CSC A;  5CSC B;  2R26 A;  1VGP A;  1CTS A;  3MSU A;  3O8J A;  4G6B A;  4CSC A;  2CSC A;  2IFC A;  6CTS A;  1CSS A; 
#chains in the Genus database with same CATH topology
 3HWK A;  4CTS A;  4TVM A;  1VGM A;  2H12 A;  4JAG A;  1IXE A;  4YBO A;  4E6Y A;  4XGH A;  2IBP A;  1AL6 A;  1NXG A;  1OWC A;  1AMZ A;  2R9E A;  1CSI A;  2CTS A;  1OWB A;  5CSC A;  4JAD A;  6CSC A;  1A59 A;  1NXE A;  1AJ8 A;  1CSC A;  2C6X A;  1IOM A;  3ENJ A;  4JAE A;  1CSH A;  4JAF A;  5CTS A;  3TQG A;  1O7X A;  2P2W A;  1CSR A;  3CSC A;  5CSC B;  2R26 A;  1VGP A;  1CTS A;  3MSU A;  3O8J A;  4G6B A;  4CSC A;  2CSC A;  2IFC A;  6CTS A;  1CSS A; 
#chains in the Genus database with same CATH homology
 3HWK A;  4CTS A;  4TVM A;  1VGM A;  2H12 A;  4JAG A;  1IXE A;  4YBO A;  4E6Y A;  4XGH A;  2IBP A;  1AL6 A;  1NXG A;  1OWC A;  1AMZ A;  2R9E A;  1CSI A;  2CTS A;  1OWB A;  5CSC A;  4JAD A;  6CSC A;  1A59 A;  1NXE A;  1AJ8 A;  1CSC A;  2C6X A;  1IOM A;  3ENJ A;  4JAE A;  1CSH A;  4JAF A;  5CTS A;  3TQG A;  1O7X A;  2P2W A;  1CSR A;  3CSC A;  5CSC B;  2R26 A;  1VGP A;  1CTS A;  3MSU A;  3O8J A;  4G6B A;  4CSC A;  2CSC A;  2IFC A;  6CTS A;  1CSS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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