5CTCA

Humanized yeast acc carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1h-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Total Genus 224
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
714
structure length
691
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLES
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Transferase/transferase inhibitor
molecule keywords Acetyl-CoA carboxylase
total genus 224
structure length 691
sequence length 714
chains with identical sequence B, C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2015-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 5ctcA02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA03
4ELSA 3PEAA 4I4ZA 1EF8A 1HNUA 4I52A 5JBXA 1MJ3A 2ZL3A 3TVWA 1XX4A 4L6WA 4EMLA 4F47A 5MGBA 3RRVA 3KTKA 3T8BA 1Q51A 2DEOA 1HZDA 4ELXA 2F9IA 4EMMA 2F6IA 5DTWA 2X58A 3OMEA 4K2NA 1XNWA 3SWXA 4OG1A 3MOYA 1DCIA 1PIXA 2CE3A 1N6DA 3KTGA 4NEKA 1DUBA 5DU8A 2QQ3A 3Q0GA 3NJDA 4QIIA 3NJBA 1SG4A 1X0UA 4MXIA 3L3SA 2VSSE 1FCFA 4MOUA 4FZWC 5DZKA 5G1RA 4YLHA 3PE8A 3TT6A 2ZL4A 2Q34A 3DJAA 3KTJA 4I42A 4LK5A 3IBBA 2UZFA 3Q7HA 2J5GD 3HINA 4RYFA 1W2XA 3HRXA 2GTRA 3T8AA 5KDRA 3KTHA 5CTBA 4FN7A 4B3JA 4DI1A 4JYJA 3Q0JA 4WZ8B 3KTIA 3OT6A 3BEZA 1WZ8A 3OC7A 3GMAA 3ST9A 2J5II 1K39A 3TLFA 4JCTA 5FIFA 4B3IA 4ZDEA 5CTCA 4FN8A 4GHNA 3STAA 3P85A 1ON9A 1SZOA 3GLMA 3FDUA 4FJWD 5C9GA 5JBWA 4HNKA 3M6MA 3QK8A 3V5IA 3TDCA 2Q2XA 2D3TA 3U9RB 3MYBA 3RSIA 3TV5A 2J5IB 3FF6A 1VRGA 3GF7A 3K8XA 2W3PA 3TVUA 4MI2A 2FZSA 2CBYA 3N6RB 3R9QA 1EF9A 1YG6A 4Z0MA 2A7KA 4B3HA 1WDLA 2FBMA 3ZW9A 4U0GH 4U1AA 3U9TB 4ZDCA 1FC6A 1Q52A 3GKBA 1JXZA 3TT7A 3P2LA 4ZDFA 4RYFH 1XNYA 4K29A 1O8UA 3ZW8A 4U18A 1TYFA 5DU6A 3T89A 3IAVA 2EJ5A 2C8TA 4IZDA 3ZWCA 2PBPA 4U0GA 1OD4A 1FC9A 4FNBA 3P5MA 3K50A 3RSTA 4KNPA 5DKPA 2F9YB 5INGA 4JSBA 5DZKH 4KD6A 1N6FA 5INIA 3IB9A 1RJMA 2PPYA 4NNQA 1YG8A 5FUSA 5G1QA 3PGQA 4Q1IA 1UIYA 3WG5A 3QXZA 4FB8A 2J5SA 4ASIA 5DUCA 2VSSA 3ZWBA 1TG6A 2A81A 4HC8A 2F9IB 2VSUC 3G64A 2ZL2A 3QYRA 3H81A 4GM2A 3KQFA 1PJHA 3H0SA 4ZU2A 3TRRA 4Q0GA 2VSUE 4U19A 5DTPA 3H0UA 2HW5A 3H0JA 4ZDDA 2ZQRA 3QREA 3HP0A 5DL1A 3R6HA 4EMPA 4RCNA 4JOTA 4IZCA 4ELWA 1K32A 4KWBA 2VSUF 2NP9A 3ZWAA 5IKLB 1UYRA 4JVTA 1XNVA 3M6NA 4JYLA 5DU4A 4K3WA 1OD2A 5C90A 3LKEA 4FZWA 1ON3A 4QFEA 3JU1A 2VSSF 1WDKA 2BZRA 3BPPA 5E0SH 4OMRA 1EY3A 3VIVA 4L8KA 4WYOB 3R0OA 2ZQQA 3H02A 4KPKA 3V5EA 4OLQA 1RJNA 4FNDA 4G2RA 3Q1TA 2FW2A 2VX2A 3U9SB 5DUFA 2J5IA 3T3WA 2IEXA 3MFMA 3PZKA 4JJTA 2VSUA 2F9YA 3MT6A 2DUBA 4U0HA 1N6EA 3GF3A 1UYTA 3H0QA 1WDMA 3R9SA 3ISAA 3T88A 1UYVA 5E0NX 1UYSA 4JCRA 4QIJA 4IZBA 5KDRB 1Y7OA 3SLLA 3BF0A 3QXIA 3HLN1 3QKAA 4WCZA 1NZYB 1J7XA 5E0SA 5INFA 3DORA 4ZDBA 3R9TA 3HE2A 5KJPA 2VREA 3TZ3A 1XO6A 2J5GA 4JCQA 2A7SA 1HNOA 3QWDA 1FC7A 2F6QA 4JWVA 5G1SA 2Q35A 2X24A 2WTBA 2ZL0A 4JFCA 2PG8A 4JCSA 3QMJA 1NZYA 3LAOA 3I47A
chains in the Genus database with same CATH superfamily
4ELSA 3PEAA 4I4ZA 1EF8A 1HNUA 4I52A 5JBXA 1MJ3A 2ZL3A 3TVWA 1XX4A 4L6WA 4EMLA 4F47A 5MGBA 3RRVA 3KTKA 3T8BA 1Q51A 2DEOA 1HZDA 4ELXA 2F9IA 4EMMA 2F6IA 5DTWA 2X58A 3OMEA 4K2NA 1XNWA 3SWXA 4OG1A 3MOYA 1DCIA 1PIXA 2CE3A 1N6DA 3KTGA 4NEKA 1DUBA 5DU8A 2QQ3A 3Q0GA 3NJDA 4QIIA 3NJBA 1SG4A 1X0UA 4MXIA 3L3SA 2VSSE 1FCFA 4MOUA 4FZWC 5DZKA 5G1RA 4YLHA 3PE8A 3TT6A 2ZL4A 2Q34A 3DJAA 3KTJA 4I42A 4LK5A 3IBBA 2UZFA 3Q7HA 2J5GD 3HINA 4RYFA 1W2XA 3HRXA 2GTRA 3T8AA 5KDRA 3KTHA 5CTBA 4FN7A 4B3JA 4DI1A 4JYJA 3Q0JA 4WZ8B 3KTIA 3OT6A 3BEZA 1WZ8A 3OC7A 3GMAA 3ST9A 2J5II 1K39A 3TLFA 4JCTA 5FIFA 4B3IA 4ZDEA 5CTCA 4FN8A 4GHNA 3STAA 3P85A 1ON9A 1SZOA 3GLMA 3FDUA 4FJWD 5C9GA 5JBWA 4HNKA 3M6MA 3QK8A 3V5IA 3TDCA 2Q2XA 2D3TA 3U9RB 3MYBA 3RSIA 3TV5A 2J5IB 3FF6A 1VRGA 3GF7A 3K8XA 2W3PA 3TVUA 4MI2A 2FZSA 2CBYA 3N6RB 3R9QA 1EF9A 1YG6A 4Z0MA 2A7KA 4B3HA 1WDLA 2FBMA 3ZW9A 4U0GH 4U1AA 3U9TB 4ZDCA 1FC6A 1Q52A 2YJGA 3GKBA 1JXZA 4NARA 3TT7A 3BPTA 3P2LA 4ZDFA 4RYFH 1XNYA 4K29A 1O8UA 3ZW8A 5HUQA 4U18A 1TYFA 5DU6A 3T89A 3IAVA 2EJ5A 2C8TA 4IZDA 3ZWCA 2PBPA 4U0GA 1OD4A 1FC9A 4FNBA 3P5MA 3K50A 3RSTA 4KNPA 5DKPA 2F9YB 5INGA 4JSBA 5DZKH 4KD6A 1N6FA 5INIA 3IB9A 1RJMA 2PPYA 4NNQA 1YG8A 5FUSA 5G1QA 3PGQA 4Q1IA 1UIYA 3WG5A 3QXZA 4FB8A 2J5SA 4ASIA 5DUCA 2VSSA 3ZWBA 1TG6A 2A81A 4HC8A 2F9IB 2VSUC 3G64A 2ZL2A 3QYRA 3H81A 4GM2A 3KQFA 1PJHA 3H0SA 4ZU2A 3TRRA 4Q0GA 2VSUE 4U19A 5DTPA 4HDTA 3H0UA 2HW5A 3H0JA 4ZDDA 2ZQRA 3QREA 3HP0A 5DL1A 3R6HA 4EMPA 4RCNA 4JOTA 4IZCA 4ELWA 1K32A 4KWBA 2VSUF 2NP9A 3ZWAA 5IKLB 1UYRA 4JVTA 1XNVA 3M6NA 4JYLA 5DU4A 4K3WA 1OD2A 5C90A 3LKEA 4FZWA 1ON3A 4QFEA 3JU1A 2VSSF 1WDKA 2BZRA 3BPPA 5E0SH 4OMRA 1EY3A 3VIVA 4L8KA 4WYOB 3R0OA 2ZQQA 3H02A 4KPKA 3V5EA 4OLQA 1RJNA 4FNDA 4G2RA 3Q1TA 2FW2A 2VX2A 3U9SB 5DUFA 2J5IA 3T3WA 2IEXA 3MFMA 3PZKA 4JJTA 2VSUA 2F9YA 3MT6A 2DUBA 4U0HA 1N6EA 3GF3A 1UYTA 3H0QA 1WDMA 3R9SA 3ISAA 3T88A 1UYVA 5E0NX 1UYSA 4JCRA 4QIJA 4IZBA 5KDRB 1Y7OA 3SLLA 3BF0A 3QXIA 3HLN1 3QKAA 4WCZA 1NZYB 1J7XA 5E0SA 5INFA 3DORA 4ZDBA 3R9TA 3HE2A 5KJPA 2VREA 3TZ3A 1XO6A 2J5GA 4JCQA 2A7SA 1HNOA 3QWDA 1FC7A 2F6QA 4JWVA 5G1SA 2Q35A 2X24A 2WTBA 2ZL0A 4JFCA 2PG8A 4JCSA 3QMJA 4J2UA 1NZYA 3LAOA 3I47A
chains in the Genus database with same CATH topology
4ELSA 3PEAA 4I4ZA 1EF8A 1HNUA 4I52A 5JBXA 1MJ3A 2ZL3A 3TVWA 1XX4A 4L6WA 4EMLA 4F47A 5MGBA 3RRVA 3KTKA 3T8BA 1Q51A 2DEOA 1HZDA 4ELXA 2F9IA 4EMMA 2F6IA 5DTWA 2X58A 3OMEA 4K2NA 1XNWA 3SWXA 4OG1A 3MOYA 1DCIA 1PIXA 2CE3A 1N6DA 3KTGA 4NEKA 1DUBA 5DU8A 2QQ3A 3Q0GA 3NJDA 4QIIA 3NJBA 1SG4A 1X0UA 4MXIA 3L3SA 2VSSE 1FCFA 4MOUA 4FZWC 5DZKA 5G1RA 4YLHA 3PE8A 3TT6A 2ZL4A 2Q34A 3DJAA 3KTJA 4I42A 4LK5A 3IBBA 2UZFA 3Q7HA 2J5GD 3HINA 4RYFA 1W2XA 3HRXA 2GTRA 3T8AA 5KDRA 3KTHA 5CTBA 4FN7A 4B3JA 4DI1A 4JYJA 3Q0JA 4WZ8B 3KTIA 3OT6A 3BEZA 1WZ8A 3OC7A 3GMAA 3ST9A 2J5II 1K39A 3TLFA 4JCTA 5FIFA 4B3IA 4ZDEA 5CTCA 4FN8A 4GHNA 3STAA 3P85A 1ON9A 1SZOA 3GLMA 3FDUA 4FJWD 5C9GA 5JBWA 4HNKA 3M6MA 3QK8A 3V5IA 3TDCA 2Q2XA 2D3TA 3U9RB 3MYBA 3RSIA 3TV5A 2J5IB 3FF6A 1VRGA 3GF7A 3K8XA 2W3PA 3TVUA 4MI2A 2FZSA 2CBYA 3N6RB 3R9QA 1EF9A 1YG6A 4Z0MA 2A7KA 4B3HA 1WDLA 2FBMA 3ZW9A 4U0GH 4U1AA 3U9TB 4ZDCA 1FC6A 1Q52A 2YJGA 3GKBA 1JXZA 4NARA 3TT7A 3BPTA 3P2LA 4ZDFA 4RYFH 1XNYA 4K29A 1O8UA 3ZW8A 5HUQA 4U18A 1TYFA 5DU6A 3T89A 3IAVA 2EJ5A 2C8TA 4IZDA 3ZWCA 2PBPA 4U0GA 1OD4A 1FC9A 4FNBA 3P5MA 3K50A 3RSTA 4KNPA 5DKPA 2F9YB 5INGA 4JSBA 5DZKH 4KD6A 1N6FA 5INIA 3IB9A 1RJMA 2PPYA 4NNQA 1YG8A 5FUSA 5G1QA 3PGQA 4Q1IA 1UIYA 3WG5A 3QXZA 4FB8A 2J5SA 4ASIA 5DUCA 2VSSA 3ZWBA 1TG6A 2A81A 4HC8A 2F9IB 2VSUC 3G64A 2ZL2A 3QYRA 3H81A 4GM2A 3KQFA 1PJHA 3H0SA 4ZU2A 3TRRA 4Q0GA 2VSUE 4U19A 5DTPA 4HDTA 3H0UA 2HW5A 3H0JA 4ZDDA 2ZQRA 3QREA 3HP0A 5DL1A 3R6HA 4EMPA 4RCNA 4JOTA 4IZCA 4ELWA 1K32A 4KWBA 2VSUF 2NP9A 3ZWAA 5IKLB 1UYRA 4JVTA 1XNVA 3M6NA 4JYLA 5DU4A 4K3WA 1OD2A 5C90A 3LKEA 4FZWA 1ON3A 4QFEA 3JU1A 2VSSF 1WDKA 2BZRA 3BPPA 5E0SH 4OMRA 1EY3A 3VIVA 4L8KA 4WYOB 3R0OA 2ZQQA 3H02A 4KPKA 3V5EA 4OLQA 1RJNA 4FNDA 4G2RA 3Q1TA 2FW2A 2VX2A 3U9SB 5DUFA 2J5IA 3T3WA 2IEXA 3MFMA 3PZKA 4JJTA 2VSUA 2F9YA 3MT6A 2DUBA 4U0HA 1N6EA 3GF3A 1UYTA 3H0QA 1WDMA 3R9SA 3ISAA 3T88A 1UYVA 5E0NX 1UYSA 4JCRA 4QIJA 4IZBA 5KDRB 1Y7OA 3SLLA 3BF0A 3QXIA 3HLN1 3QKAA 4WCZA 1NZYB 1J7XA 5E0SA 5INFA 3DORA 4ZDBA 3R9TA 3HE2A 5KJPA 2VREA 3TZ3A 1XO6A 2J5GA 4JCQA 2A7SA 1HNOA 3QWDA 1FC7A 2F6QA 4JWVA 5G1SA 2Q35A 2X24A 2WTBA 2ZL0A 4JFCA 2PG8A 4JCSA 3QMJA 4J2UA 1NZYA 3LAOA 3I47A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ELS A;  3PEA A;  4I4Z A;  1EF8 A;  1HNU A;  4I52 A;  5JBX A;  1MJ3 A;  2ZL3 A;  3TVW A;  1XX4 A;  4L6W A;  4EML A;  4F47 A;  5MGB A;  3RRV A;  3KTK A;  3T8B A;  1Q51 A;  2DEO A;  1HZD A;  4ELX A;  2F9I A;  4EMM A;  2F6I A;  5DTW A;  2X58 A;  3OME A;  4K2N A;  1XNW A;  3SWX A;  4OG1 A;  3MOY A;  1DCI A;  1PIX A;  2CE3 A;  1N6D A;  3KTG A;  4NEK A;  1DUB A;  5DU8 A;  2QQ3 A;  3Q0G A;  3NJD A;  4QII A;  3NJB A;  1SG4 A;  1X0U A;  4MXI A;  3L3S A;  2VSS E;  1FCF A;  4MOU A;  4FZW C;  5DZK A;  5G1R A;  4YLH A;  3PE8 A;  3TT6 A;  2ZL4 A;  2Q34 A;  3DJA A;  3KTJ A;  4I42 A;  4LK5 A;  3IBB A;  2UZF A;  3Q7H A;  2J5G D;  3HIN A;  4RYF A;  1W2X A;  3HRX A;  2GTR A;  3T8A A;  5KDR A;  3KTH A;  5CTB A;  4FN7 A;  4B3J A;  4DI1 A;  4JYJ A;  3Q0J A;  4WZ8 B;  3KTI A;  3OT6 A;  3BEZ A;  1WZ8 A;  3OC7 A;  3GMA A;  3ST9 A;  2J5I I;  1K39 A;  3TLF A;  4JCT A;  5FIF A;  4B3I A;  4ZDE A;  5CTC A;  4FN8 A;  4GHN A;  3STA A;  3P85 A;  1ON9 A;  1SZO A;  3GLM A;  3FDU A;  4FJW D;  5C9G A;  5JBW A;  4HNK A;  3M6M A;  3QK8 A;  3V5I A;  3TDC A;  2Q2X A;  2D3T A;  3U9R B;  3MYB A;  3RSI A;  3TV5 A;  2J5I B;  3FF6 A;  1VRG A;  3GF7 A;  3K8X A;  2W3P A;  3TVU A;  4MI2 A;  2FZS A;  2CBY A;  3N6R B;  3R9Q A;  1EF9 A;  1YG6 A;  4Z0M A;  2A7K A;  4B3H A;  1WDL A;  2FBM A;  3ZW9 A;  4U0G H;  4U1A A;  3U9T B;  4ZDC A;  1FC6 A;  1Q52 A;  3GKB A;  1JXZ A;  3TT7 A;  3P2L A;  4ZDF A;  4RYF H;  1XNY A;  4K29 A;  1O8U A;  3ZW8 A;  4U18 A;  1TYF A;  5DU6 A;  3T89 A;  3IAV A;  2EJ5 A;  2C8T A;  4IZD A;  3ZWC A;  2PBP A;  4U0G A;  1OD4 A;  1FC9 A;  4FNB A;  3P5M A;  3K50 A;  3RST A;  4KNP A;  5DKP A;  2F9Y B;  5ING A;  4JSB A;  5DZK H;  4KD6 A;  1N6F A;  5INI A;  3IB9 A;  1RJM A;  2PPY A;  4NNQ A;  1YG8 A;  5FUS A;  5G1Q A;  3PGQ A;  4Q1I A;  1UIY A;  3WG5 A;  3QXZ A;  4FB8 A;  2J5S A;  4ASI A;  5DUC A;  2VSS A;  3ZWB A;  1TG6 A;  2A81 A;  4HC8 A;  2F9I B;  2VSU C;  3G64 A;  2ZL2 A;  3QYR A;  3H81 A;  4GM2 A;  3KQF A;  1PJH A;  3H0S A;  4ZU2 A;  3TRR A;  4Q0G A;  2VSU E;  4U19 A;  5DTP A;  3H0U A;  2HW5 A;  3H0J A;  4ZDD A;  2ZQR A;  3QRE A;  3HP0 A;  5DL1 A;  3R6H A;  4EMP A;  4RCN A;  4JOT A;  4IZC A;  4ELW A;  1K32 A;  4KWB A;  2VSU F;  2NP9 A;  3ZWA A;  5IKL B;  1UYR A;  4JVT A;  1XNV A;  3M6N A;  4JYL A;  5DU4 A;  4K3W A;  1OD2 A;  5C90 A;  3LKE A;  4FZW A;  1ON3 A;  4QFE A;  3JU1 A;  2VSS F;  1WDK A;  2BZR A;  3BPP A;  5E0S H;  4OMR A;  1EY3 A;  3VIV A;  4L8K A;  4WYO B;  3R0O A;  2ZQQ A;  3H02 A;  4KPK A;  3V5E A;  4OLQ A;  1RJN A;  4FND A;  4G2R A;  3Q1T A;  2FW2 A;  2VX2 A;  3U9S B;  5DUF A;  2J5I A;  3T3W A;  2IEX A;  3MFM A;  3PZK A;  4JJT A;  2VSU A;  2F9Y A;  3MT6 A;  2DUB A;  4U0H A;  1N6E A;  3GF3 A;  1UYT A;  3H0Q A;  1WDM A;  3R9S A;  3ISA A;  3T88 A;  1UYV A;  5E0N X;  1UYS A;  4JCR A;  4QIJ A;  4IZB A;  5KDR B;  1Y7O A;  3SLL A;  3BF0 A;  3QXI A;  3HLN 1;  3QKA A;  4WCZ A;  1NZY B;  1J7X A;  5E0S A;  5INF A;  3DOR A;  4ZDB A;  3R9T A;  3HE2 A;  5KJP A;  2VRE A;  3TZ3 A;  1XO6 A;  2J5G A;  4JCQ A;  2A7S A;  1HNO A;  3QWD A;  1FC7 A;  2F6Q A;  4JWV A;  5G1S A;  2Q35 A;  2X24 A;  2WTB A;  2ZL0 A;  4JFC A;  2PG8 A;  4JCS A;  3QMJ A;  1NZY A;  3LAO A;  3I47 A; 
#chains in the Genus database with same CATH topology
 4ELS A;  3PEA A;  4I4Z A;  1EF8 A;  1HNU A;  4I52 A;  5JBX A;  1MJ3 A;  2ZL3 A;  3TVW A;  1XX4 A;  4L6W A;  4EML A;  4F47 A;  5MGB A;  3RRV A;  3KTK A;  3T8B A;  1Q51 A;  2DEO A;  1HZD A;  4ELX A;  2F9I A;  4EMM A;  2F6I A;  5DTW A;  2X58 A;  3OME A;  4K2N A;  1XNW A;  3SWX A;  4OG1 A;  3MOY A;  1DCI A;  1PIX A;  2CE3 A;  1N6D A;  3KTG A;  4NEK A;  1DUB A;  5DU8 A;  2QQ3 A;  3Q0G A;  3NJD A;  4QII A;  3NJB A;  1SG4 A;  1X0U A;  4MXI A;  3L3S A;  2VSS E;  1FCF A;  4MOU A;  4FZW C;  5DZK A;  5G1R A;  4YLH A;  3PE8 A;  3TT6 A;  2ZL4 A;  2Q34 A;  3DJA A;  3KTJ A;  4I42 A;  4LK5 A;  3IBB A;  2UZF A;  3Q7H A;  2J5G D;  3HIN A;  4RYF A;  1W2X A;  3HRX A;  2GTR A;  3T8A A;  5KDR A;  3KTH A;  5CTB A;  4FN7 A;  4B3J A;  4DI1 A;  4JYJ A;  3Q0J A;  4WZ8 B;  3KTI A;  3OT6 A;  3BEZ A;  1WZ8 A;  3OC7 A;  3GMA A;  3ST9 A;  2J5I I;  1K39 A;  3TLF A;  4JCT A;  5FIF A;  4B3I A;  4ZDE A;  5CTC A;  4FN8 A;  4GHN A;  3STA A;  3P85 A;  1ON9 A;  1SZO A;  3GLM A;  3FDU A;  4FJW D;  5C9G A;  5JBW A;  4HNK A;  3M6M A;  3QK8 A;  3V5I A;  3TDC A;  2Q2X A;  2D3T A;  3U9R B;  3MYB A;  3RSI A;  3TV5 A;  2J5I B;  3FF6 A;  1VRG A;  3GF7 A;  3K8X A;  2W3P A;  3TVU A;  4MI2 A;  2FZS A;  2CBY A;  3N6R B;  3R9Q A;  1EF9 A;  1YG6 A;  4Z0M A;  2A7K A;  4B3H A;  1WDL A;  2FBM A;  3ZW9 A;  4U0G H;  4U1A A;  3U9T B;  4ZDC A;  1FC6 A;  1Q52 A;  2YJG A;  3GKB A;  1JXZ A;  4NAR A;  3TT7 A;  3BPT A;  3P2L A;  4ZDF A;  4RYF H;  1XNY A;  4K29 A;  1O8U A;  3ZW8 A;  5HUQ A;  4U18 A;  1TYF A;  5DU6 A;  3T89 A;  3IAV A;  2EJ5 A;  2C8T A;  4IZD A;  3ZWC A;  2PBP A;  4U0G A;  1OD4 A;  1FC9 A;  4FNB A;  3P5M A;  3K50 A;  3RST A;  4KNP A;  5DKP A;  2F9Y B;  5ING A;  4JSB A;  5DZK H;  4KD6 A;  1N6F A;  5INI A;  3IB9 A;  1RJM A;  2PPY A;  4NNQ A;  1YG8 A;  5FUS A;  5G1Q A;  3PGQ A;  4Q1I A;  1UIY A;  3WG5 A;  3QXZ A;  4FB8 A;  2J5S A;  4ASI A;  5DUC A;  2VSS A;  3ZWB A;  1TG6 A;  2A81 A;  4HC8 A;  2F9I B;  2VSU C;  3G64 A;  2ZL2 A;  3QYR A;  3H81 A;  4GM2 A;  3KQF A;  1PJH A;  3H0S A;  4ZU2 A;  3TRR A;  4Q0G A;  2VSU E;  4U19 A;  5DTP A;  4HDT A;  3H0U A;  2HW5 A;  3H0J A;  4ZDD A;  2ZQR A;  3QRE A;  3HP0 A;  5DL1 A;  3R6H A;  4EMP A;  4RCN A;  4JOT A;  4IZC A;  4ELW A;  1K32 A;  4KWB A;  2VSU F;  2NP9 A;  3ZWA A;  5IKL B;  1UYR A;  4JVT A;  1XNV A;  3M6N A;  4JYL A;  5DU4 A;  4K3W A;  1OD2 A;  5C90 A;  3LKE A;  4FZW A;  1ON3 A;  4QFE A;  3JU1 A;  2VSS F;  1WDK A;  2BZR A;  3BPP A;  5E0S H;  4OMR A;  1EY3 A;  3VIV A;  4L8K A;  4WYO B;  3R0O A;  2ZQQ A;  3H02 A;  4KPK A;  3V5E A;  4OLQ A;  1RJN A;  4FND A;  4G2R A;  3Q1T A;  2FW2 A;  2VX2 A;  3U9S B;  5DUF A;  2J5I A;  3T3W A;  2IEX A;  3MFM A;  3PZK A;  4JJT A;  2VSU A;  2F9Y A;  3MT6 A;  2DUB A;  4U0H A;  1N6E A;  3GF3 A;  1UYT A;  3H0Q A;  1WDM A;  3R9S A;  3ISA A;  3T88 A;  1UYV A;  5E0N X;  1UYS A;  4JCR A;  4QIJ A;  4IZB A;  5KDR B;  1Y7O A;  3SLL A;  3BF0 A;  3QXI A;  3HLN 1;  3QKA A;  4WCZ A;  1NZY B;  1J7X A;  5E0S A;  5INF A;  3DOR A;  4ZDB A;  3R9T A;  3HE2 A;  5KJP A;  2VRE A;  3TZ3 A;  1XO6 A;  2J5G A;  4JCQ A;  2A7S A;  1HNO A;  3QWD A;  1FC7 A;  2F6Q A;  4JWV A;  5G1S A;  2Q35 A;  2X24 A;  2WTB A;  2ZL0 A;  4JFC A;  2PG8 A;  4JCS A;  3QMJ A;  4J2U A;  1NZY A;  3LAO A;  3I47 A; 
#chains in the Genus database with same CATH homology
 4ELS A;  3PEA A;  4I4Z A;  1EF8 A;  1HNU A;  4I52 A;  5JBX A;  1MJ3 A;  2ZL3 A;  3TVW A;  1XX4 A;  4L6W A;  4EML A;  4F47 A;  5MGB A;  3RRV A;  3KTK A;  3T8B A;  1Q51 A;  2DEO A;  1HZD A;  4ELX A;  2F9I A;  4EMM A;  2F6I A;  5DTW A;  2X58 A;  3OME A;  4K2N A;  1XNW A;  3SWX A;  4OG1 A;  3MOY A;  1DCI A;  1PIX A;  2CE3 A;  1N6D A;  3KTG A;  4NEK A;  1DUB A;  5DU8 A;  2QQ3 A;  3Q0G A;  3NJD A;  4QII A;  3NJB A;  1SG4 A;  1X0U A;  4MXI A;  3L3S A;  2VSS E;  1FCF A;  4MOU A;  4FZW C;  5DZK A;  5G1R A;  4YLH A;  3PE8 A;  3TT6 A;  2ZL4 A;  2Q34 A;  3DJA A;  3KTJ A;  4I42 A;  4LK5 A;  3IBB A;  2UZF A;  3Q7H A;  2J5G D;  3HIN A;  4RYF A;  1W2X A;  3HRX A;  2GTR A;  3T8A A;  5KDR A;  3KTH A;  5CTB A;  4FN7 A;  4B3J A;  4DI1 A;  4JYJ A;  3Q0J A;  4WZ8 B;  3KTI A;  3OT6 A;  3BEZ A;  1WZ8 A;  3OC7 A;  3GMA A;  3ST9 A;  2J5I I;  1K39 A;  3TLF A;  4JCT A;  5FIF A;  4B3I A;  4ZDE A;  5CTC A;  4FN8 A;  4GHN A;  3STA A;  3P85 A;  1ON9 A;  1SZO A;  3GLM A;  3FDU A;  4FJW D;  5C9G A;  5JBW A;  4HNK A;  3M6M A;  3QK8 A;  3V5I A;  3TDC A;  2Q2X A;  2D3T A;  3U9R B;  3MYB A;  3RSI A;  3TV5 A;  2J5I B;  3FF6 A;  1VRG A;  3GF7 A;  3K8X A;  2W3P A;  3TVU A;  4MI2 A;  2FZS A;  2CBY A;  3N6R B;  3R9Q A;  1EF9 A;  1YG6 A;  4Z0M A;  2A7K A;  4B3H A;  1WDL A;  2FBM A;  3ZW9 A;  4U0G H;  4U1A A;  3U9T B;  4ZDC A;  1FC6 A;  1Q52 A;  2YJG A;  3GKB A;  1JXZ A;  4NAR A;  3TT7 A;  3BPT A;  3P2L A;  4ZDF A;  4RYF H;  1XNY A;  4K29 A;  1O8U A;  3ZW8 A;  5HUQ A;  4U18 A;  1TYF A;  5DU6 A;  3T89 A;  3IAV A;  2EJ5 A;  2C8T A;  4IZD A;  3ZWC A;  2PBP A;  4U0G A;  1OD4 A;  1FC9 A;  4FNB A;  3P5M A;  3K50 A;  3RST A;  4KNP A;  5DKP A;  2F9Y B;  5ING A;  4JSB A;  5DZK H;  4KD6 A;  1N6F A;  5INI A;  3IB9 A;  1RJM A;  2PPY A;  4NNQ A;  1YG8 A;  5FUS A;  5G1Q A;  3PGQ A;  4Q1I A;  1UIY A;  3WG5 A;  3QXZ A;  4FB8 A;  2J5S A;  4ASI A;  5DUC A;  2VSS A;  3ZWB A;  1TG6 A;  2A81 A;  4HC8 A;  2F9I B;  2VSU C;  3G64 A;  2ZL2 A;  3QYR A;  3H81 A;  4GM2 A;  3KQF A;  1PJH A;  3H0S A;  4ZU2 A;  3TRR A;  4Q0G A;  2VSU E;  4U19 A;  5DTP A;  4HDT A;  3H0U A;  2HW5 A;  3H0J A;  4ZDD A;  2ZQR A;  3QRE A;  3HP0 A;  5DL1 A;  3R6H A;  4EMP A;  4RCN A;  4JOT A;  4IZC A;  4ELW A;  1K32 A;  4KWB A;  2VSU F;  2NP9 A;  3ZWA A;  5IKL B;  1UYR A;  4JVT A;  1XNV A;  3M6N A;  4JYL A;  5DU4 A;  4K3W A;  1OD2 A;  5C90 A;  3LKE A;  4FZW A;  1ON3 A;  4QFE A;  3JU1 A;  2VSS F;  1WDK A;  2BZR A;  3BPP A;  5E0S H;  4OMR A;  1EY3 A;  3VIV A;  4L8K A;  4WYO B;  3R0O A;  2ZQQ A;  3H02 A;  4KPK A;  3V5E A;  4OLQ A;  1RJN A;  4FND A;  4G2R A;  3Q1T A;  2FW2 A;  2VX2 A;  3U9S B;  5DUF A;  2J5I A;  3T3W A;  2IEX A;  3MFM A;  3PZK A;  4JJT A;  2VSU A;  2F9Y A;  3MT6 A;  2DUB A;  4U0H A;  1N6E A;  3GF3 A;  1UYT A;  3H0Q A;  1WDM A;  3R9S A;  3ISA A;  3T88 A;  1UYV A;  5E0N X;  1UYS A;  4JCR A;  4QIJ A;  4IZB A;  5KDR B;  1Y7O A;  3SLL A;  3BF0 A;  3QXI A;  3HLN 1;  3QKA A;  4WCZ A;  1NZY B;  1J7X A;  5E0S A;  5INF A;  3DOR A;  4ZDB A;  3R9T A;  3HE2 A;  5KJP A;  2VRE A;  3TZ3 A;  1XO6 A;  2J5G A;  4JCQ A;  2A7S A;  1HNO A;  3QWD A;  1FC7 A;  2F6Q A;  4JWV A;  5G1S A;  2Q35 A;  2X24 A;  2WTB A;  2ZL0 A;  4JFC A;  2PG8 A;  4JCS A;  3QMJ A;  4J2U A;  1NZY A;  3LAO A;  3I47 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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