5CTCA

Humanized yeast acc carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1h-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Total Genus 224
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
714
structure length
691
Chain Sequence
b'LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLES'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Acetyl-CoA carboxylase
publication title Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Transferase/transferase inhibitor
total genus 224
structure length 691
sequence length 714
chains with identical sequence B, C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2015-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 5ctcA02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA03
4U19A 1JXZA 2F9IB 2F9YA 4ZDCA 1XNVA 1XNWA 2J5GA 3MYBA 5G1RA 2VSSF 4QIIA 3ZW8A 2J5IA 5E0SH 4L6WA 5C9GA 5KJPA 4FN7A 4JJTA 5DUFA 3WG5A 2Q34A 1OD4A 3DORA 3TVUA 4G2RA 5MGBA 3TLFA 1YG8A 2Q2XA 3RSTA 4QFEA 2VREA 1MJ3A 5INIA 2VX2A 4JSBA 3QWDA 3LKEA 1N6DA 2Q35A 4QIJA 2F9YB 1TYFA 3STAA 1WZ8A 3KTJA 5E0SA 3IBBA 4IZBA 2VSSE 4B3JA 5KDRA 1VRGA 1X0UA 1Y7OA 2F6QA 2J5IB 3RSIA 3R0OA 3GLMA 3QYRA 4JOTA 1K39A 2J5GD 3QK8A 4I4ZA 3H0SA 3QMJA 2F9IA 2A7KA 3VIVA 3T8AA 3TT7A 2VSSA 5DL1A 4ELWA 3JU1A 2UZFA 1FC6A 1WDLA 1YG6A 4GHNA 4YLHA 5DKPA 4DI1A 3P5MA 2PPYA 4JYLA 4RCNA 4WYOB 3GKBA 4WZ8B 1HNUA 3T89A 3TV5A 2X58A 5DU4A 5DZKH 2PBPA 1UYSA 4LK5A 3P2LA 3MFMA 3OT6A 3Q0JA 2W3PA 4KNPA 3U9TB 1Q51A 1EF8A 4FN8A 4MI2A 3MT6A 4EMLA 3QXZA 3TT6A 4B3HA 2DUBA 4FZWC 3T88A 3BF0A 4JYJA 3RRVA 4ZU2A 2FZSA 2ZL3A 3K8XA 3GF3A 3H81A 3H0QA 3Q0GA 3L3SA 1OD2A 5DZKA 4ZDDA 3PEAA 3ZWBA 4WCZA 1HZDA 4I42A 2HW5A 3H0JA 2BZRA 1UYTA 3TVWA 3HE2A 1DUBA 1FC7A 3R9QA 3N6RB 5IKLB 3U9SB 3SWXA 2ZL0A 1FCFA 2CE3A 2J5II 4JVTA 5INGA 3OMEA 4GM2A 4NEKA 2ZQRA 2J5SA 4HC8A 3HLN1 3KTIA 4U0GH 4ZDFA 3OC7A 4F47A 3IAVA 3DJAA 1UYRA 3K50A 1SZOA 5CTCA 1XX4A 1FC9A 3NJDA 2NP9A 4IZDA 2ZQQA 4Q0GA 5INFA 5G1SA 4JCTA 1N6EA 4FB8A 5DUCA 2A7SA 4ZDBA 3V5EA 2IEXA 3BEZA 4OMRA 4U0HA 3ZW9A 4K29A 3ZWAA 4EMMA 5JBXA 4MOUA 3H0UA 3GF7A 2QQ3A 3Q1TA 4U0GA 5G1QA 4HNKA 5DTPA 4RYFA 4FNBA 3KTHA 1DCIA 5FIFA 3M6MA 3I47A 1K32A 1XO6A 3ZWCA 4JCQA 1XNYA 4B3IA 3FF6A 3T3WA 4JCSA 2WTBA 3R6HA 4KD6A 3KQFA 3GMAA 3G64A 3ISAA 1EY3A 4JFCA 4NNQA 3V5IA 2A81A 3TRRA 4JCRA 1PJHA 3FDUA 4JWVA 3PZKA 1TG6A 4K3WA 4I52A 4L8KA 2D3TA 2ZL2A 5CTBA 3ST9A 4ASIA 1NZYA 3NJBA 3HRXA 3U9RB 2PG8A 3M6NA 3P85A 3T8BA 4FZWA 4MXIA 2FW2A 2C8TA 4ZDEA 1ON9A 1ON3A 3SLLA 4Q1IA 3TDCA 1O8UA 1W2XA 3IB9A 1WDKA 3PE8A 4KPKA 1HNOA 4KWBA 2X24A 2VSUF 1UIYA 3HP0A 4ELXA 1UYVA 2CBYA 3HINA 3MOYA 4RYFH 3R9SA 2FBMA 3QXIA 1SG4A 1NZYB 2DEOA 5C90A 5DU8A 5FUSA 4U18A 4FJWD 4U1AA 3PGQA 3LAOA 4IZCA 5DTWA 4FNDA 1RJMA 3KTKA 3R9TA 2F6IA 2VSUC 4OG1A 3TZ3A 3BPPA 1J7XA 1RJNA 1N6FA 5DU6A 1WDMA 2VSUE 1PIXA 3KTGA 2EJ5A 1Q52A 4OLQA 2ZL4A 5JBWA 3H02A 5KDRB 3QKAA 4ELSA 2GTRA 3Q7HA 5E0NX 2VSUA 3QREA 4Z0MA 4EMPA 1EF9A 4K2NA
chains in the Genus database with same CATH superfamily
4U19A 1JXZA 2F9IB 2F9YA 4ZDCA 1XNVA 1XNWA 2J5GA 3MYBA 5G1RA 2VSSF 4QIIA 3ZW8A 2J5IA 5E0SH 4L6WA 5C9GA 5KJPA 4FN7A 4JJTA 5DUFA 3WG5A 2Q34A 1OD4A 3DORA 3TVUA 4G2RA 5MGBA 3TLFA 1YG8A 2Q2XA 3RSTA 4QFEA 2VREA 1MJ3A 5INIA 5HUQA 2VX2A 4JSBA 3QWDA 3LKEA 1N6DA 2Q35A 4QIJA 2F9YB 4J2UA 1TYFA 3STAA 1WZ8A 3KTJA 5E0SA 3IBBA 4IZBA 2VSSE 4B3JA 5KDRA 1VRGA 1X0UA 1Y7OA 2F6QA 2J5IB 3RSIA 3R0OA 3GLMA 3QYRA 4JOTA 1K39A 2J5GD 3QK8A 4I4ZA 3H0SA 3QMJA 2F9IA 2A7KA 3VIVA 4HDTA 3T8AA 3TT7A 2VSSA 5DL1A 4ELWA 3JU1A 2UZFA 1FC6A 1WDLA 1YG6A 4GHNA 4YLHA 5DKPA 4DI1A 3P5MA 2PPYA 4JYLA 4RCNA 4WYOB 3GKBA 4WZ8B 1HNUA 3T89A 2YJGA 3TV5A 2X58A 5DU4A 5DZKH 2PBPA 1UYSA 4LK5A 3P2LA 3MFMA 3OT6A 3Q0JA 2W3PA 4KNPA 3U9TB 1Q51A 1EF8A 4FN8A 4MI2A 3MT6A 4EMLA 3QXZA 3TT6A 4B3HA 2DUBA 4FZWC 3T88A 3BF0A 4JYJA 3RRVA 4ZU2A 2FZSA 2ZL3A 3K8XA 3GF3A 3H81A 3H0QA 3Q0GA 3L3SA 1OD2A 5DZKA 4ZDDA 3PEAA 3ZWBA 4WCZA 1HZDA 4I42A 2HW5A 3H0JA 2BZRA 1UYTA 3TVWA 3HE2A 1DUBA 1FC7A 3R9QA 3N6RB 5IKLB 3U9SB 3SWXA 2ZL0A 1FCFA 2CE3A 2J5II 4JVTA 5INGA 3OMEA 4GM2A 4NEKA 2ZQRA 2J5SA 4HC8A 3HLN1 3KTIA 4U0GH 4ZDFA 3OC7A 4F47A 3IAVA 3DJAA 1UYRA 3K50A 1SZOA 5CTCA 1XX4A 1FC9A 3NJDA 2NP9A 4IZDA 2ZQQA 4Q0GA 5INFA 5G1SA 4JCTA 1N6EA 4FB8A 5DUCA 2A7SA 4ZDBA 3V5EA 2IEXA 3BEZA 4OMRA 4U0HA 3ZW9A 4K29A 3ZWAA 3BPTA 4EMMA 5JBXA 4MOUA 3H0UA 3GF7A 2QQ3A 3Q1TA 4U0GA 5G1QA 4HNKA 5DTPA 4RYFA 4FNBA 3KTHA 1DCIA 5FIFA 3M6MA 3I47A 1K32A 1XO6A 3ZWCA 4JCQA 1XNYA 4B3IA 3FF6A 3T3WA 4JCSA 2WTBA 3R6HA 4KD6A 3KQFA 3GMAA 3G64A 3ISAA 1EY3A 4JFCA 4NNQA 3V5IA 2A81A 3TRRA 4JCRA 1PJHA 3FDUA 4JWVA 3PZKA 1TG6A 4K3WA 4I52A 4L8KA 2D3TA 2ZL2A 5CTBA 3ST9A 4ASIA 1NZYA 3NJBA 3HRXA 3U9RB 2PG8A 3M6NA 3P85A 4FZWA 3T8BA 4MXIA 2FW2A 2C8TA 4ZDEA 1ON9A 4NARA 1ON3A 3SLLA 4Q1IA 3TDCA 1O8UA 1W2XA 3IB9A 1WDKA 3PE8A 4KPKA 1HNOA 4KWBA 2X24A 2VSUF 1UIYA 3HP0A 4ELXA 1UYVA 2CBYA 3HINA 3MOYA 4RYFH 3R9SA 2FBMA 3QXIA 1SG4A 1NZYB 2DEOA 5C90A 5DU8A 5FUSA 4U18A 4FJWD 4U1AA 3PGQA 3LAOA 4IZCA 5DTWA 4FNDA 1RJMA 3KTKA 3R9TA 2F6IA 2VSUC 4OG1A 3TZ3A 3BPPA 1J7XA 1RJNA 1N6FA 5DU6A 1WDMA 2VSUE 1PIXA 3KTGA 2EJ5A 1Q52A 4OLQA 2ZL4A 5JBWA 3H02A 5KDRB 3QKAA 4ELSA 2GTRA 3Q7HA 5E0NX 2VSUA 3QREA 4Z0MA 4EMPA 1EF9A 4K2NA
chains in the Genus database with same CATH topology
4U19A 1JXZA 2F9IB 2F9YA 4ZDCA 1XNVA 1XNWA 2J5GA 3MYBA 5G1RA 2VSSF 4QIIA 3ZW8A 2J5IA 5E0SH 4L6WA 5C9GA 5KJPA 4FN7A 4JJTA 5DUFA 3WG5A 2Q34A 1OD4A 3DORA 3TVUA 4G2RA 5MGBA 3TLFA 1YG8A 2Q2XA 3RSTA 4QFEA 2VREA 1MJ3A 5INIA 5HUQA 2VX2A 4JSBA 3QWDA 3LKEA 1N6DA 2Q35A 4QIJA 2F9YB 4J2UA 1TYFA 3STAA 1WZ8A 3KTJA 5E0SA 3IBBA 4IZBA 2VSSE 4B3JA 5KDRA 1VRGA 1X0UA 1Y7OA 2F6QA 2J5IB 3RSIA 3R0OA 3GLMA 3QYRA 4JOTA 1K39A 2J5GD 3QK8A 4I4ZA 3H0SA 3QMJA 2F9IA 2A7KA 3VIVA 4HDTA 3T8AA 3TT7A 2VSSA 5DL1A 4ELWA 3JU1A 2UZFA 1FC6A 1WDLA 1YG6A 4GHNA 4YLHA 5DKPA 4DI1A 3P5MA 2PPYA 4JYLA 4RCNA 4WYOB 3GKBA 4WZ8B 1HNUA 3T89A 2YJGA 3TV5A 2X58A 5DU4A 5DZKH 2PBPA 1UYSA 4LK5A 3P2LA 3MFMA 3OT6A 3Q0JA 2W3PA 4KNPA 3U9TB 1Q51A 1EF8A 4FN8A 4MI2A 3MT6A 4EMLA 3QXZA 3TT6A 4B3HA 2DUBA 4FZWC 3T88A 3BF0A 4JYJA 3RRVA 4ZU2A 2FZSA 2ZL3A 3K8XA 3GF3A 3H81A 3H0QA 3Q0GA 3L3SA 1OD2A 5DZKA 4ZDDA 3PEAA 3ZWBA 4WCZA 1HZDA 4I42A 2HW5A 3H0JA 2BZRA 1UYTA 3TVWA 3HE2A 1DUBA 1FC7A 3R9QA 3N6RB 5IKLB 3U9SB 3SWXA 2ZL0A 1FCFA 2CE3A 2J5II 4JVTA 5INGA 3OMEA 4GM2A 4NEKA 2ZQRA 2J5SA 4HC8A 3HLN1 3KTIA 4U0GH 4ZDFA 3OC7A 4F47A 3IAVA 3DJAA 1UYRA 3K50A 1SZOA 5CTCA 1XX4A 1FC9A 3NJDA 2NP9A 4IZDA 2ZQQA 4Q0GA 5INFA 5G1SA 4JCTA 1N6EA 4FB8A 5DUCA 2A7SA 4ZDBA 3V5EA 2IEXA 3BEZA 4OMRA 4U0HA 3ZW9A 4K29A 3ZWAA 3BPTA 4EMMA 5JBXA 4MOUA 3H0UA 3GF7A 2QQ3A 3Q1TA 4U0GA 5G1QA 4HNKA 5DTPA 4RYFA 4FNBA 3KTHA 1DCIA 5FIFA 3M6MA 3I47A 1K32A 1XO6A 3ZWCA 4JCQA 1XNYA 4B3IA 3FF6A 3T3WA 4JCSA 2WTBA 3R6HA 4KD6A 3KQFA 3GMAA 3G64A 3ISAA 1EY3A 4JFCA 4NNQA 3V5IA 2A81A 3TRRA 4JCRA 1PJHA 3FDUA 4JWVA 3PZKA 1TG6A 4K3WA 4I52A 4L8KA 2D3TA 2ZL2A 5CTBA 3ST9A 4ASIA 1NZYA 3NJBA 3HRXA 3U9RB 2PG8A 3M6NA 3P85A 4FZWA 3T8BA 4MXIA 2FW2A 2C8TA 4ZDEA 1ON9A 4NARA 1ON3A 3SLLA 4Q1IA 3TDCA 1O8UA 1W2XA 3IB9A 1WDKA 3PE8A 4KPKA 1HNOA 4KWBA 2X24A 2VSUF 1UIYA 3HP0A 4ELXA 1UYVA 2CBYA 3HINA 3MOYA 4RYFH 3R9SA 2FBMA 3QXIA 1SG4A 1NZYB 2DEOA 5C90A 5DU8A 5FUSA 4U18A 4FJWD 4U1AA 3PGQA 3LAOA 4IZCA 5DTWA 4FNDA 1RJMA 3KTKA 3R9TA 2F6IA 2VSUC 4OG1A 3TZ3A 3BPPA 1J7XA 1RJNA 1N6FA 5DU6A 1WDMA 2VSUE 1PIXA 3KTGA 2EJ5A 1Q52A 4OLQA 2ZL4A 5JBWA 3H02A 5KDRB 3QKAA 4ELSA 2GTRA 3Q7HA 5E0NX 2VSUA 3QREA 4Z0MA 4EMPA 1EF9A 4K2NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U19 A;  1JXZ A;  2F9I B;  2F9Y A;  4ZDC A;  1XNV A;  1XNW A;  2J5G A;  3MYB A;  5G1R A;  2VSS F;  4QII A;  3ZW8 A;  2J5I A;  5E0S H;  4L6W A;  5C9G A;  5KJP A;  4FN7 A;  4JJT A;  5DUF A;  3WG5 A;  2Q34 A;  1OD4 A;  3DOR A;  3TVU A;  4G2R A;  5MGB A;  3TLF A;  1YG8 A;  2Q2X A;  3RST A;  4QFE A;  2VRE A;  1MJ3 A;  5INI A;  2VX2 A;  4JSB A;  3QWD A;  3LKE A;  1N6D A;  2Q35 A;  4QIJ A;  2F9Y B;  1TYF A;  3STA A;  1WZ8 A;  3KTJ A;  5E0S A;  3IBB A;  4IZB A;  2VSS E;  4B3J A;  5KDR A;  1VRG A;  1X0U A;  1Y7O A;  2F6Q A;  2J5I B;  3RSI A;  3R0O A;  3GLM A;  3QYR A;  4JOT A;  1K39 A;  2J5G D;  3QK8 A;  4I4Z A;  3H0S A;  3QMJ A;  2F9I A;  2A7K A;  3VIV A;  3T8A A;  3TT7 A;  2VSS A;  5DL1 A;  4ELW A;  3JU1 A;  2UZF A;  1FC6 A;  1WDL A;  1YG6 A;  4GHN A;  4YLH A;  5DKP A;  4DI1 A;  3P5M A;  2PPY A;  4JYL A;  4RCN A;  4WYO B;  3GKB A;  4WZ8 B;  1HNU A;  3T89 A;  3TV5 A;  2X58 A;  5DU4 A;  5DZK H;  2PBP A;  1UYS A;  4LK5 A;  3P2L A;  3MFM A;  3OT6 A;  3Q0J A;  2W3P A;  4KNP A;  3U9T B;  1Q51 A;  1EF8 A;  4FN8 A;  4MI2 A;  3MT6 A;  4EML A;  3QXZ A;  3TT6 A;  4B3H A;  2DUB A;  4FZW C;  3T88 A;  3BF0 A;  4JYJ A;  3RRV A;  4ZU2 A;  2FZS A;  2ZL3 A;  3K8X A;  3GF3 A;  3H81 A;  3H0Q A;  3Q0G A;  3L3S A;  1OD2 A;  5DZK A;  4ZDD A;  3PEA A;  3ZWB A;  4WCZ A;  1HZD A;  4I42 A;  2HW5 A;  3H0J A;  2BZR A;  1UYT A;  3TVW A;  3HE2 A;  1DUB A;  1FC7 A;  3R9Q A;  3N6R B;  5IKL B;  3U9S B;  3SWX A;  2ZL0 A;  1FCF A;  2CE3 A;  2J5I I;  4JVT A;  5ING A;  3OME A;  4GM2 A;  4NEK A;  2ZQR A;  2J5S A;  4HC8 A;  3HLN 1;  3KTI A;  4U0G H;  4ZDF A;  3OC7 A;  4F47 A;  3IAV A;  3DJA A;  1UYR A;  3K50 A;  1SZO A;  5CTC A;  1XX4 A;  1FC9 A;  3NJD A;  2NP9 A;  4IZD A;  2ZQQ A;  4Q0G A;  5INF A;  5G1S A;  4JCT A;  1N6E A;  4FB8 A;  5DUC A;  2A7S A;  4ZDB A;  3V5E A;  2IEX A;  3BEZ A;  4OMR A;  4U0H A;  3ZW9 A;  4K29 A;  3ZWA A;  4EMM A;  5JBX A;  4MOU A;  3H0U A;  3GF7 A;  2QQ3 A;  3Q1T A;  4U0G A;  5G1Q A;  4HNK A;  5DTP A;  4RYF A;  4FNB A;  3KTH A;  1DCI A;  5FIF A;  3M6M A;  3I47 A;  1K32 A;  1XO6 A;  3ZWC A;  4JCQ A;  1XNY A;  4B3I A;  3FF6 A;  3T3W A;  4JCS A;  2WTB A;  3R6H A;  4KD6 A;  3KQF A;  3GMA A;  3G64 A;  3ISA A;  1EY3 A;  4JFC A;  4NNQ A;  3V5I A;  2A81 A;  3TRR A;  4JCR A;  1PJH A;  3FDU A;  4JWV A;  3PZK A;  1TG6 A;  4K3W A;  4I52 A;  4L8K A;  2D3T A;  2ZL2 A;  5CTB A;  3ST9 A;  4ASI A;  1NZY A;  3NJB A;  3HRX A;  3U9R B;  2PG8 A;  3M6N A;  3P85 A;  3T8B A;  4FZW A;  4MXI A;  2FW2 A;  2C8T A;  4ZDE A;  1ON9 A;  1ON3 A;  3SLL A;  4Q1I A;  3TDC A;  1O8U A;  1W2X A;  3IB9 A;  1WDK A;  3PE8 A;  4KPK A;  1HNO A;  4KWB A;  2X24 A;  2VSU F;  1UIY A;  3HP0 A;  4ELX A;  1UYV A;  2CBY A;  3HIN A;  3MOY A;  4RYF H;  3R9S A;  2FBM A;  3QXI A;  1SG4 A;  1NZY B;  2DEO A;  5C90 A;  5DU8 A;  5FUS A;  4U18 A;  4FJW D;  4U1A A;  3PGQ A;  3LAO A;  4IZC A;  5DTW A;  4FND A;  1RJM A;  3KTK A;  3R9T A;  2F6I A;  2VSU C;  4OG1 A;  3TZ3 A;  3BPP A;  1J7X A;  1RJN A;  1N6F A;  5DU6 A;  1WDM A;  2VSU E;  1PIX A;  3KTG A;  2EJ5 A;  1Q52 A;  4OLQ A;  2ZL4 A;  5JBW A;  3H02 A;  5KDR B;  3QKA A;  4ELS A;  2GTR A;  3Q7H A;  5E0N X;  2VSU A;  3QRE A;  4Z0M A;  4EMP A;  1EF9 A;  4K2N A; 
#chains in the Genus database with same CATH topology
 4U19 A;  1JXZ A;  2F9I B;  2F9Y A;  4ZDC A;  1XNV A;  1XNW A;  2J5G A;  3MYB A;  5G1R A;  2VSS F;  4QII A;  3ZW8 A;  2J5I A;  5E0S H;  4L6W A;  5C9G A;  5KJP A;  4FN7 A;  4JJT A;  5DUF A;  3WG5 A;  2Q34 A;  1OD4 A;  3DOR A;  3TVU A;  4G2R A;  5MGB A;  3TLF A;  1YG8 A;  2Q2X A;  3RST A;  4QFE A;  2VRE A;  1MJ3 A;  5INI A;  5HUQ A;  2VX2 A;  4JSB A;  3QWD A;  3LKE A;  1N6D A;  2Q35 A;  4QIJ A;  2F9Y B;  4J2U A;  1TYF A;  3STA A;  1WZ8 A;  3KTJ A;  5E0S A;  3IBB A;  4IZB A;  2VSS E;  4B3J A;  5KDR A;  1VRG A;  1X0U A;  1Y7O A;  2F6Q A;  2J5I B;  3RSI A;  3R0O A;  3GLM A;  3QYR A;  4JOT A;  1K39 A;  2J5G D;  3QK8 A;  4I4Z A;  3H0S A;  3QMJ A;  2F9I A;  2A7K A;  3VIV A;  4HDT A;  3T8A A;  3TT7 A;  2VSS A;  5DL1 A;  4ELW A;  3JU1 A;  2UZF A;  1FC6 A;  1WDL A;  1YG6 A;  4GHN A;  4YLH A;  5DKP A;  4DI1 A;  3P5M A;  2PPY A;  4JYL A;  4RCN A;  4WYO B;  3GKB A;  4WZ8 B;  1HNU A;  3T89 A;  2YJG A;  3TV5 A;  2X58 A;  5DU4 A;  5DZK H;  2PBP A;  1UYS A;  4LK5 A;  3P2L A;  3MFM A;  3OT6 A;  3Q0J A;  2W3P A;  4KNP A;  3U9T B;  1Q51 A;  1EF8 A;  4FN8 A;  4MI2 A;  3MT6 A;  4EML A;  3QXZ A;  3TT6 A;  4B3H A;  2DUB A;  4FZW C;  3T88 A;  3BF0 A;  4JYJ A;  3RRV A;  4ZU2 A;  2FZS A;  2ZL3 A;  3K8X A;  3GF3 A;  3H81 A;  3H0Q A;  3Q0G A;  3L3S A;  1OD2 A;  5DZK A;  4ZDD A;  3PEA A;  3ZWB A;  4WCZ A;  1HZD A;  4I42 A;  2HW5 A;  3H0J A;  2BZR A;  1UYT A;  3TVW A;  3HE2 A;  1DUB A;  1FC7 A;  3R9Q A;  3N6R B;  5IKL B;  3U9S B;  3SWX A;  2ZL0 A;  1FCF A;  2CE3 A;  2J5I I;  4JVT A;  5ING A;  3OME A;  4GM2 A;  4NEK A;  2ZQR A;  2J5S A;  4HC8 A;  3HLN 1;  3KTI A;  4U0G H;  4ZDF A;  3OC7 A;  4F47 A;  3IAV A;  3DJA A;  1UYR A;  3K50 A;  1SZO A;  5CTC A;  1XX4 A;  1FC9 A;  3NJD A;  2NP9 A;  4IZD A;  2ZQQ A;  4Q0G A;  5INF A;  5G1S A;  4JCT A;  1N6E A;  4FB8 A;  5DUC A;  2A7S A;  4ZDB A;  3V5E A;  2IEX A;  3BEZ A;  4OMR A;  4U0H A;  3ZW9 A;  4K29 A;  3ZWA A;  3BPT A;  4EMM A;  5JBX A;  4MOU A;  3H0U A;  3GF7 A;  2QQ3 A;  3Q1T A;  4U0G A;  5G1Q A;  4HNK A;  5DTP A;  4RYF A;  4FNB A;  3KTH A;  1DCI A;  5FIF A;  3M6M A;  3I47 A;  1K32 A;  1XO6 A;  3ZWC A;  4JCQ A;  1XNY A;  4B3I A;  3FF6 A;  3T3W A;  4JCS A;  2WTB A;  3R6H A;  4KD6 A;  3KQF A;  3GMA A;  3G64 A;  3ISA A;  1EY3 A;  4JFC A;  4NNQ A;  3V5I A;  2A81 A;  3TRR A;  4JCR A;  1PJH A;  3FDU A;  4JWV A;  3PZK A;  1TG6 A;  4K3W A;  4I52 A;  4L8K A;  2D3T A;  2ZL2 A;  5CTB A;  3ST9 A;  4ASI A;  1NZY A;  3NJB A;  3HRX A;  3U9R B;  2PG8 A;  3M6N A;  3P85 A;  4FZW A;  3T8B A;  4MXI A;  2FW2 A;  2C8T A;  4ZDE A;  1ON9 A;  4NAR A;  1ON3 A;  3SLL A;  4Q1I A;  3TDC A;  1O8U A;  1W2X A;  3IB9 A;  1WDK A;  3PE8 A;  4KPK A;  1HNO A;  4KWB A;  2X24 A;  2VSU F;  1UIY A;  3HP0 A;  4ELX A;  1UYV A;  2CBY A;  3HIN A;  3MOY A;  4RYF H;  3R9S A;  2FBM A;  3QXI A;  1SG4 A;  1NZY B;  2DEO A;  5C90 A;  5DU8 A;  5FUS A;  4U18 A;  4FJW D;  4U1A A;  3PGQ A;  3LAO A;  4IZC A;  5DTW A;  4FND A;  1RJM A;  3KTK A;  3R9T A;  2F6I A;  2VSU C;  4OG1 A;  3TZ3 A;  3BPP A;  1J7X A;  1RJN A;  1N6F A;  5DU6 A;  1WDM A;  2VSU E;  1PIX A;  3KTG A;  2EJ5 A;  1Q52 A;  4OLQ A;  2ZL4 A;  5JBW A;  3H02 A;  5KDR B;  3QKA A;  4ELS A;  2GTR A;  3Q7H A;  5E0N X;  2VSU A;  3QRE A;  4Z0M A;  4EMP A;  1EF9 A;  4K2N A; 
#chains in the Genus database with same CATH homology
 4U19 A;  1JXZ A;  2F9I B;  2F9Y A;  4ZDC A;  1XNV A;  1XNW A;  2J5G A;  3MYB A;  5G1R A;  2VSS F;  4QII A;  3ZW8 A;  2J5I A;  5E0S H;  4L6W A;  5C9G A;  5KJP A;  4FN7 A;  4JJT A;  5DUF A;  3WG5 A;  2Q34 A;  1OD4 A;  3DOR A;  3TVU A;  4G2R A;  5MGB A;  3TLF A;  1YG8 A;  2Q2X A;  3RST A;  4QFE A;  2VRE A;  1MJ3 A;  5INI A;  5HUQ A;  2VX2 A;  4JSB A;  3QWD A;  3LKE A;  1N6D A;  2Q35 A;  4QIJ A;  2F9Y B;  4J2U A;  1TYF A;  3STA A;  1WZ8 A;  3KTJ A;  5E0S A;  3IBB A;  4IZB A;  2VSS E;  4B3J A;  5KDR A;  1VRG A;  1X0U A;  1Y7O A;  2F6Q A;  2J5I B;  3RSI A;  3R0O A;  3GLM A;  3QYR A;  4JOT A;  1K39 A;  2J5G D;  3QK8 A;  4I4Z A;  3H0S A;  3QMJ A;  2F9I A;  2A7K A;  3VIV A;  4HDT A;  3T8A A;  3TT7 A;  2VSS A;  5DL1 A;  4ELW A;  3JU1 A;  2UZF A;  1FC6 A;  1WDL A;  1YG6 A;  4GHN A;  4YLH A;  5DKP A;  4DI1 A;  3P5M A;  2PPY A;  4JYL A;  4RCN A;  4WYO B;  3GKB A;  4WZ8 B;  1HNU A;  3T89 A;  2YJG A;  3TV5 A;  2X58 A;  5DU4 A;  5DZK H;  2PBP A;  1UYS A;  4LK5 A;  3P2L A;  3MFM A;  3OT6 A;  3Q0J A;  2W3P A;  4KNP A;  3U9T B;  1Q51 A;  1EF8 A;  4FN8 A;  4MI2 A;  3MT6 A;  4EML A;  3QXZ A;  3TT6 A;  4B3H A;  2DUB A;  4FZW C;  3T88 A;  3BF0 A;  4JYJ A;  3RRV A;  4ZU2 A;  2FZS A;  2ZL3 A;  3K8X A;  3GF3 A;  3H81 A;  3H0Q A;  3Q0G A;  3L3S A;  1OD2 A;  5DZK A;  4ZDD A;  3PEA A;  3ZWB A;  4WCZ A;  1HZD A;  4I42 A;  2HW5 A;  3H0J A;  2BZR A;  1UYT A;  3TVW A;  3HE2 A;  1DUB A;  1FC7 A;  3R9Q A;  3N6R B;  5IKL B;  3U9S B;  3SWX A;  2ZL0 A;  1FCF A;  2CE3 A;  2J5I I;  4JVT A;  5ING A;  3OME A;  4GM2 A;  4NEK A;  2ZQR A;  2J5S A;  4HC8 A;  3HLN 1;  3KTI A;  4U0G H;  4ZDF A;  3OC7 A;  4F47 A;  3IAV A;  3DJA A;  1UYR A;  3K50 A;  1SZO A;  5CTC A;  1XX4 A;  1FC9 A;  3NJD A;  2NP9 A;  4IZD A;  2ZQQ A;  4Q0G A;  5INF A;  5G1S A;  4JCT A;  1N6E A;  4FB8 A;  5DUC A;  2A7S A;  4ZDB A;  3V5E A;  2IEX A;  3BEZ A;  4OMR A;  4U0H A;  3ZW9 A;  4K29 A;  3ZWA A;  3BPT A;  4EMM A;  5JBX A;  4MOU A;  3H0U A;  3GF7 A;  2QQ3 A;  3Q1T A;  4U0G A;  5G1Q A;  4HNK A;  5DTP A;  4RYF A;  4FNB A;  3KTH A;  1DCI A;  5FIF A;  3M6M A;  3I47 A;  1K32 A;  1XO6 A;  3ZWC A;  4JCQ A;  1XNY A;  4B3I A;  3FF6 A;  3T3W A;  4JCS A;  2WTB A;  3R6H A;  4KD6 A;  3KQF A;  3GMA A;  3G64 A;  3ISA A;  1EY3 A;  4JFC A;  4NNQ A;  3V5I A;  2A81 A;  3TRR A;  4JCR A;  1PJH A;  3FDU A;  4JWV A;  3PZK A;  1TG6 A;  4K3W A;  4I52 A;  4L8K A;  2D3T A;  2ZL2 A;  5CTB A;  3ST9 A;  4ASI A;  1NZY A;  3NJB A;  3HRX A;  3U9R B;  2PG8 A;  3M6N A;  3P85 A;  4FZW A;  3T8B A;  4MXI A;  2FW2 A;  2C8T A;  4ZDE A;  1ON9 A;  4NAR A;  1ON3 A;  3SLL A;  4Q1I A;  3TDC A;  1O8U A;  1W2X A;  3IB9 A;  1WDK A;  3PE8 A;  4KPK A;  1HNO A;  4KWB A;  2X24 A;  2VSU F;  1UIY A;  3HP0 A;  4ELX A;  1UYV A;  2CBY A;  3HIN A;  3MOY A;  4RYF H;  3R9S A;  2FBM A;  3QXI A;  1SG4 A;  1NZY B;  2DEO A;  5C90 A;  5DU8 A;  5FUS A;  4U18 A;  4FJW D;  4U1A A;  3PGQ A;  3LAO A;  4IZC A;  5DTW A;  4FND A;  1RJM A;  3KTK A;  3R9T A;  2F6I A;  2VSU C;  4OG1 A;  3TZ3 A;  3BPP A;  1J7X A;  1RJN A;  1N6F A;  5DU6 A;  1WDM A;  2VSU E;  1PIX A;  3KTG A;  2EJ5 A;  1Q52 A;  4OLQ A;  2ZL4 A;  5JBW A;  3H02 A;  5KDR B;  3QKA A;  4ELS A;  2GTR A;  3Q7H A;  5E0N X;  2VSU A;  3QRE A;  4Z0M A;  4EMP A;  1EF9 A;  4K2N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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