5CTCA

Humanized yeast acc carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1h-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Total Genus 224
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
714
structure length
691
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGLKLES
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Saccharomyces cerevisiae
molecule keywords Acetyl-CoA carboxylase
total genus 224
structure length 691
sequence length 714
chains with identical sequence B, C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2015-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 5ctcA02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 5ctcA03
1RJMA 3BEZA 3GMAA 1K32A 2F9IA 3ST9A 4IZCA 4F47A 2FBMA 5JBXA 3TDCA 3QK8A 3DORA 4ZDCA 1EY3A 3HLN1 3OMEA 3H0SA 3LAOA 4FN8A 5DUFA 3PGQA 3HE2A 4OMRA 4ELXA 3I47A 3Q0GA 1UYVA 4ZDFA 1DCIA 3MT6A 4K3WA 4QIJA 2ZQRA 2X24A 2Q35A 2X58A 4QIIA 3ZW8A 3T88A 1EF8A 5E0SA 1UYTA 1N6FA 3ZWBA 3TVWA 2DUBA 2GTRA 3PZKA 1UIYA 4I4ZA 4L8KA 4FNDA 2D3TA 3NJDA 5INIA 3R6HA 5DL1A 4ELSA 3M6NA 2VSUF 4ZDEA 4EMLA 3QXZA 4K29A 3Q7HA 4ZU2A 3GLMA 2FZSA 5CTCA 4ZDDA 3PE8A 4FB8A 3R9SA 3P2LA 3HINA 2VSSF 4HC8A 4OLQA 2BZRA 3ZWAA 3LKEA 4Q1IA 3U9RB 3MOYA 2HW5A 1DUBA 4FNBA 3H0JA 3SLLA 2J5GA 3V5IA 5C9GA 5DTWA 5INGA 2Q2XA 3P5MA 3NJBA 3MYBA 1W2XA 4I42A 4Q0GA 4U1AA 3TV5A 3T89A 3QMJA 3H02A 1ON3A 4DI1A 2CE3A 3Q0JA 3T3WA 3KQFA 2VSSE 3OT6A 3PEAA 1JXZA 1Y7OA 4JCQA 2W3PA 3BF0A 1XNYA 1XNWA 2ZL4A 4EMPA 1WDLA 4JOTA 4RYFA 1PJHA 1Q51A 3U9TB 1SG4A 4RCNA 2F6QA 5G1QA 4JYLA 1N6DA 1PIXA 1J7XA 3T8AA 5E0SH 1XO6A 5KJPA 2J5GD 4U0HA 2ZL2A 4JSBA 3KTIA 1XNVA 3P85A 3IAVA 4JFCA 2A7SA 1YG8A 4NNQA 1NZYB 3RSTA 4JYJA 3ZW9A 3HP0A 4IZBA 3TT7A 2DEOA 4B3IA 3KTJA 5G1SA 1WZ8A 3GF3A 3H81A 1O8UA 4WCZA 4L6WA 1HZDA 1RJNA 1NZYA 3QKAA 5DZKA 3DJAA 2VX2A 5DUCA 2CBYA 4Z0MA 3TT6A 4KD6A 5DU6A 4JJTA 2NP9A 4LK5A 3QREA 4ZDBA 5IKLB 3QWDA 5MGBA 2QQ3A 3RSIA 3H0UA 3KTKA 3STAA 3TRRA 1K39A 4U0GA 5CTBA 4GHNA 3L3SA 1SZOA 4JCRA 5FUSA 2A81A 1OD4A 1YG6A 4KWBA 4YLHA 4HNKA 3T8BA 4WZ8B 4WYOB 1FC7A 4ASIA 4JCSA 1FCFA 2VSUA 3U9SB 4RYFH 4QFEA 2A7KA 3KTGA 3IBBA 3M6MA 2FW2A 2F9YB 3Q1TA 3IB9A 2VSUC 1Q52A 4MXIA 3TVUA 2UZFA 3FF6A 3V5EA 2VSSA 4JVTA 1N6EA 5DKPA 4IZDA 1MJ3A 4MOUA 3H0QA 3GKBA 1ON9A 3MFMA 1UYRA 1UYSA 4G2RA 4GM2A 4MI2A 4FN7A 4JWVA 2F9YA 3N6RB 3TLFA 4NEKA 1VRGA 4JCTA 3BPPA 4FZWA 1FC9A 3G64A 3FDUA 4K2NA 3KTHA 2WTBA 2Q34A 5KDRB 1TYFA 4FZWC 1XX4A 3K50A 5DZKH 2ZL0A 5DU4A 5JBWA 2C8TA 4KPKA 2ZL3A 2J5IB 2EJ5A 4I52A 1EF9A 3ZWCA 1OD2A 3ISAA 3TZ3A 4KNPA 5DU8A 4EMMA 5KDRA 4U0GH 5E0NX 1HNUA 2F6IA 2J5II 4B3JA 1TG6A 4U18A 4B3HA 3HRXA 3R0OA 3SWXA 1X0UA 2J5IA 2IEXA 2J5SA 5C90A 3OC7A 1HNOA 3QYRA 3K8XA 1FC6A 2F9IB 5FIFA 2VREA 4U19A 1WDMA 4OG1A 4FJWD 3QXIA 2PPYA 3VIVA 3R9TA 3WG5A 2ZQQA 3JU1A 5DTPA 5G1RA 4ELWA 2PBPA 3RRVA 2VSUE 1WDKA 2PG8A 3R9QA 3GF7A 5INFA
chains in the Genus database with same CATH superfamily
1RJMA 3BEZA 3GMAA 1K32A 2F9IA 3ST9A 4IZCA 4F47A 2FBMA 5JBXA 3TDCA 3QK8A 3DORA 4ZDCA 1EY3A 3HLN1 3OMEA 3H0SA 3LAOA 4FN8A 5DUFA 3PGQA 3HE2A 4OMRA 4ELXA 3I47A 3Q0GA 1UYVA 4ZDFA 1DCIA 3MT6A 4K3WA 4QIJA 2ZQRA 2X24A 2Q35A 2X58A 4QIIA 3ZW8A 3T88A 1EF8A 5E0SA 1UYTA 1N6FA 3ZWBA 3TVWA 2DUBA 2GTRA 3PZKA 1UIYA 4I4ZA 4L8KA 4FNDA 2D3TA 3NJDA 5INIA 3R6HA 5DL1A 4ELSA 3M6NA 2VSUF 4ZDEA 4EMLA 3QXZA 4K29A 3Q7HA 4ZU2A 3GLMA 2FZSA 5CTCA 4ZDDA 3PE8A 4FB8A 3R9SA 3P2LA 3HINA 2VSSF 4HC8A 4OLQA 2BZRA 3ZWAA 3LKEA 4Q1IA 3U9RB 3MOYA 2HW5A 1DUBA 4FNBA 3H0JA 3SLLA 2J5GA 3V5IA 5C9GA 5DTWA 5INGA 2Q2XA 3P5MA 3NJBA 3MYBA 1W2XA 4I42A 4Q0GA 4U1AA 3TV5A 3T89A 3QMJA 3H02A 1ON3A 4DI1A 2CE3A 3Q0JA 3T3WA 3KQFA 2VSSE 3OT6A 3PEAA 1JXZA 1Y7OA 4JCQA 2W3PA 3BF0A 1XNYA 1XNWA 3BPTA 2ZL4A 4EMPA 1WDLA 4JOTA 4RYFA 1PJHA 1Q51A 3U9TB 1SG4A 4RCNA 2F6QA 5G1QA 4JYLA 1N6DA 1PIXA 1J7XA 3T8AA 5E0SH 1XO6A 5KJPA 4HDTA 2J5GD 4U0HA 2ZL2A 4JSBA 3KTIA 1XNVA 3P85A 4J2UA 3IAVA 4JFCA 2A7SA 1YG8A 4NNQA 1NZYB 3RSTA 4JYJA 3ZW9A 3HP0A 4IZBA 3TT7A 2DEOA 4B3IA 3KTJA 5G1SA 1WZ8A 3GF3A 3H81A 1O8UA 4WCZA 4L6WA 1HZDA 1RJNA 1NZYA 3QKAA 5DZKA 3DJAA 2VX2A 5DUCA 2CBYA 4Z0MA 3TT6A 4KD6A 5DU6A 4JJTA 2NP9A 4LK5A 3QREA 4ZDBA 5IKLB 3QWDA 5MGBA 2QQ3A 3RSIA 3H0UA 3KTKA 3STAA 3TRRA 1K39A 4U0GA 5CTBA 4GHNA 3L3SA 1SZOA 4JCRA 5FUSA 2A81A 1OD4A 1YG6A 4KWBA 4YLHA 4HNKA 3T8BA 4WZ8B 4WYOB 1FC7A 4ASIA 4JCSA 1FCFA 2VSUA 3U9SB 4RYFH 4QFEA 2A7KA 3KTGA 3IBBA 4NARA 3M6MA 2FW2A 2F9YB 3Q1TA 3IB9A 2VSUC 1Q52A 4MXIA 3TVUA 2UZFA 3FF6A 3V5EA 2VSSA 4JVTA 1N6EA 5DKPA 4IZDA 1MJ3A 4MOUA 3H0QA 3GKBA 1ON9A 2YJGA 3MFMA 5HUQA 1UYRA 1UYSA 4G2RA 4GM2A 4MI2A 4FN7A 4JWVA 2F9YA 3N6RB 3TLFA 4NEKA 1VRGA 4JCTA 3BPPA 4FZWA 1FC9A 3G64A 3FDUA 4K2NA 3KTHA 2WTBA 2Q34A 5KDRB 1TYFA 4FZWC 1XX4A 3K50A 5DZKH 2ZL0A 5DU4A 5JBWA 2C8TA 4KPKA 2ZL3A 2J5IB 2EJ5A 4I52A 1EF9A 3ZWCA 1OD2A 3ISAA 3TZ3A 4KNPA 5DU8A 4EMMA 5KDRA 4U0GH 5E0NX 1HNUA 2F6IA 2J5II 4B3JA 1TG6A 4U18A 4B3HA 3HRXA 3R0OA 3SWXA 1X0UA 2J5IA 2IEXA 2J5SA 5C90A 3OC7A 1HNOA 3QYRA 3K8XA 1FC6A 2F9IB 5FIFA 2VREA 4U19A 1WDMA 4OG1A 4FJWD 3QXIA 2PPYA 3VIVA 3R9TA 3WG5A 2ZQQA 3JU1A 5DTPA 5G1RA 4ELWA 2PBPA 3RRVA 2VSUE 1WDKA 2PG8A 3R9QA 3GF7A 5INFA
chains in the Genus database with same CATH topology
1RJMA 3BEZA 3GMAA 1K32A 2F9IA 3ST9A 4IZCA 4F47A 2FBMA 5JBXA 3TDCA 3QK8A 3DORA 4ZDCA 1EY3A 3HLN1 3OMEA 3H0SA 3LAOA 4FN8A 5DUFA 3PGQA 3HE2A 4OMRA 4ELXA 3I47A 3Q0GA 1UYVA 4ZDFA 1DCIA 3MT6A 4K3WA 4QIJA 2ZQRA 2X24A 2Q35A 2X58A 4QIIA 3ZW8A 3T88A 1EF8A 5E0SA 1UYTA 1N6FA 3ZWBA 3TVWA 2DUBA 2GTRA 3PZKA 1UIYA 4I4ZA 4L8KA 4FNDA 2D3TA 3NJDA 5INIA 3R6HA 5DL1A 4ELSA 3M6NA 2VSUF 4ZDEA 4EMLA 3QXZA 4K29A 3Q7HA 4ZU2A 3GLMA 2FZSA 5CTCA 4ZDDA 3PE8A 4FB8A 3R9SA 3P2LA 3HINA 2VSSF 4HC8A 4OLQA 2BZRA 3ZWAA 3LKEA 4Q1IA 3U9RB 3MOYA 2HW5A 1DUBA 4FNBA 3H0JA 3SLLA 2J5GA 3V5IA 5C9GA 5DTWA 5INGA 2Q2XA 3P5MA 3NJBA 3MYBA 1W2XA 4I42A 4Q0GA 4U1AA 3TV5A 3T89A 3QMJA 3H02A 1ON3A 4DI1A 2CE3A 3Q0JA 3T3WA 3KQFA 2VSSE 3OT6A 3PEAA 1JXZA 1Y7OA 4JCQA 2W3PA 3BF0A 1XNYA 1XNWA 3BPTA 2ZL4A 4EMPA 1WDLA 4JOTA 4RYFA 1PJHA 1Q51A 3U9TB 1SG4A 4RCNA 2F6QA 5G1QA 4JYLA 1N6DA 1PIXA 1J7XA 3T8AA 5E0SH 1XO6A 5KJPA 4HDTA 2J5GD 4U0HA 2ZL2A 4JSBA 3KTIA 1XNVA 3P85A 4J2UA 3IAVA 4JFCA 2A7SA 1YG8A 4NNQA 1NZYB 3RSTA 4JYJA 3ZW9A 3HP0A 4IZBA 3TT7A 2DEOA 4B3IA 3KTJA 5G1SA 1WZ8A 3GF3A 3H81A 1O8UA 4WCZA 4L6WA 1HZDA 1RJNA 1NZYA 3QKAA 5DZKA 3DJAA 2VX2A 5DUCA 2CBYA 4Z0MA 3TT6A 4KD6A 5DU6A 4JJTA 2NP9A 4LK5A 3QREA 4ZDBA 5IKLB 3QWDA 5MGBA 2QQ3A 3RSIA 3H0UA 3KTKA 3STAA 3TRRA 1K39A 4U0GA 5CTBA 4GHNA 3L3SA 1SZOA 4JCRA 5FUSA 2A81A 1OD4A 1YG6A 4KWBA 4YLHA 4HNKA 3T8BA 4WZ8B 4WYOB 1FC7A 4ASIA 4JCSA 1FCFA 2VSUA 3U9SB 4RYFH 4QFEA 2A7KA 3KTGA 3IBBA 4NARA 3M6MA 2FW2A 2F9YB 3Q1TA 3IB9A 2VSUC 1Q52A 4MXIA 3TVUA 2UZFA 3FF6A 3V5EA 2VSSA 4JVTA 1N6EA 5DKPA 4IZDA 1MJ3A 4MOUA 3H0QA 3GKBA 1ON9A 2YJGA 3MFMA 5HUQA 1UYRA 1UYSA 4G2RA 4GM2A 4MI2A 4FN7A 4JWVA 2F9YA 3N6RB 3TLFA 4NEKA 1VRGA 4JCTA 3BPPA 4FZWA 1FC9A 3G64A 3FDUA 4K2NA 3KTHA 2WTBA 2Q34A 5KDRB 1TYFA 4FZWC 1XX4A 3K50A 5DZKH 2ZL0A 5DU4A 5JBWA 2C8TA 4KPKA 2ZL3A 2J5IB 2EJ5A 4I52A 1EF9A 3ZWCA 1OD2A 3ISAA 3TZ3A 4KNPA 5DU8A 4EMMA 5KDRA 4U0GH 5E0NX 1HNUA 2F6IA 2J5II 4B3JA 1TG6A 4U18A 4B3HA 3HRXA 3R0OA 3SWXA 1X0UA 2J5IA 2IEXA 2J5SA 5C90A 3OC7A 1HNOA 3QYRA 3K8XA 1FC6A 2F9IB 5FIFA 2VREA 4U19A 1WDMA 4OG1A 4FJWD 3QXIA 2PPYA 3VIVA 3R9TA 3WG5A 2ZQQA 3JU1A 5DTPA 5G1RA 4ELWA 2PBPA 3RRVA 2VSUE 1WDKA 2PG8A 3R9QA 3GF7A 5INFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RJM A;  3BEZ A;  3GMA A;  1K32 A;  2F9I A;  3ST9 A;  4IZC A;  4F47 A;  2FBM A;  5JBX A;  3TDC A;  3QK8 A;  3DOR A;  4ZDC A;  1EY3 A;  3HLN 1;  3OME A;  3H0S A;  3LAO A;  4FN8 A;  5DUF A;  3PGQ A;  3HE2 A;  4OMR A;  4ELX A;  3I47 A;  3Q0G A;  1UYV A;  4ZDF A;  1DCI A;  3MT6 A;  4K3W A;  4QIJ A;  2ZQR A;  2X24 A;  2Q35 A;  2X58 A;  4QII A;  3ZW8 A;  3T88 A;  1EF8 A;  5E0S A;  1UYT A;  1N6F A;  3ZWB A;  3TVW A;  2DUB A;  2GTR A;  3PZK A;  1UIY A;  4I4Z A;  4L8K A;  4FND A;  2D3T A;  3NJD A;  5INI A;  3R6H A;  5DL1 A;  4ELS A;  3M6N A;  2VSU F;  4ZDE A;  4EML A;  3QXZ A;  4K29 A;  3Q7H A;  4ZU2 A;  3GLM A;  2FZS A;  5CTC A;  4ZDD A;  3PE8 A;  4FB8 A;  3R9S A;  3P2L A;  3HIN A;  2VSS F;  4HC8 A;  4OLQ A;  2BZR A;  3ZWA A;  3LKE A;  4Q1I A;  3U9R B;  3MOY A;  2HW5 A;  1DUB A;  4FNB A;  3H0J A;  3SLL A;  2J5G A;  3V5I A;  5C9G A;  5DTW A;  5ING A;  2Q2X A;  3P5M A;  3NJB A;  3MYB A;  1W2X A;  4I42 A;  4Q0G A;  4U1A A;  3TV5 A;  3T89 A;  3QMJ A;  3H02 A;  1ON3 A;  4DI1 A;  2CE3 A;  3Q0J A;  3T3W A;  3KQF A;  2VSS E;  3OT6 A;  3PEA A;  1JXZ A;  1Y7O A;  4JCQ A;  2W3P A;  3BF0 A;  1XNY A;  1XNW A;  2ZL4 A;  4EMP A;  1WDL A;  4JOT A;  4RYF A;  1PJH A;  1Q51 A;  3U9T B;  1SG4 A;  4RCN A;  2F6Q A;  5G1Q A;  4JYL A;  1N6D A;  1PIX A;  1J7X A;  3T8A A;  5E0S H;  1XO6 A;  5KJP A;  2J5G D;  4U0H A;  2ZL2 A;  4JSB A;  3KTI A;  1XNV A;  3P85 A;  3IAV A;  4JFC A;  2A7S A;  1YG8 A;  4NNQ A;  1NZY B;  3RST A;  4JYJ A;  3ZW9 A;  3HP0 A;  4IZB A;  3TT7 A;  2DEO A;  4B3I A;  3KTJ A;  5G1S A;  1WZ8 A;  3GF3 A;  3H81 A;  1O8U A;  4WCZ A;  4L6W A;  1HZD A;  1RJN A;  1NZY A;  3QKA A;  5DZK A;  3DJA A;  2VX2 A;  5DUC A;  2CBY A;  4Z0M A;  3TT6 A;  4KD6 A;  5DU6 A;  4JJT A;  2NP9 A;  4LK5 A;  3QRE A;  4ZDB A;  5IKL B;  3QWD A;  5MGB A;  2QQ3 A;  3RSI A;  3H0U A;  3KTK A;  3STA A;  3TRR A;  1K39 A;  4U0G A;  5CTB A;  4GHN A;  3L3S A;  1SZO A;  4JCR A;  5FUS A;  2A81 A;  1OD4 A;  1YG6 A;  4KWB A;  4YLH A;  4HNK A;  3T8B A;  4WZ8 B;  4WYO B;  1FC7 A;  4ASI A;  4JCS A;  1FCF A;  2VSU A;  3U9S B;  4RYF H;  4QFE A;  2A7K A;  3KTG A;  3IBB A;  3M6M A;  2FW2 A;  2F9Y B;  3Q1T A;  3IB9 A;  2VSU C;  1Q52 A;  4MXI A;  3TVU A;  2UZF A;  3FF6 A;  3V5E A;  2VSS A;  4JVT A;  1N6E A;  5DKP A;  4IZD A;  1MJ3 A;  4MOU A;  3H0Q A;  3GKB A;  1ON9 A;  3MFM A;  1UYR A;  1UYS A;  4G2R A;  4GM2 A;  4MI2 A;  4FN7 A;  4JWV A;  2F9Y A;  3N6R B;  3TLF A;  4NEK A;  1VRG A;  4JCT A;  3BPP A;  4FZW A;  1FC9 A;  3G64 A;  3FDU A;  4K2N A;  3KTH A;  2WTB A;  2Q34 A;  5KDR B;  1TYF A;  4FZW C;  1XX4 A;  3K50 A;  5DZK H;  2ZL0 A;  5DU4 A;  5JBW A;  2C8T A;  4KPK A;  2ZL3 A;  2J5I B;  2EJ5 A;  4I52 A;  1EF9 A;  3ZWC A;  1OD2 A;  3ISA A;  3TZ3 A;  4KNP A;  5DU8 A;  4EMM A;  5KDR A;  4U0G H;  5E0N X;  1HNU A;  2F6I A;  2J5I I;  4B3J A;  1TG6 A;  4U18 A;  4B3H A;  3HRX A;  3R0O A;  3SWX A;  1X0U A;  2J5I A;  2IEX A;  2J5S A;  5C90 A;  3OC7 A;  1HNO A;  3QYR A;  3K8X A;  1FC6 A;  2F9I B;  5FIF A;  2VRE A;  4U19 A;  1WDM A;  4OG1 A;  4FJW D;  3QXI A;  2PPY A;  3VIV A;  3R9T A;  3WG5 A;  2ZQQ A;  3JU1 A;  5DTP A;  5G1R A;  4ELW A;  2PBP A;  3RRV A;  2VSU E;  1WDK A;  2PG8 A;  3R9Q A;  3GF7 A;  5INF A; 
#chains in the Genus database with same CATH topology
 1RJM A;  3BEZ A;  3GMA A;  1K32 A;  2F9I A;  3ST9 A;  4IZC A;  4F47 A;  2FBM A;  5JBX A;  3TDC A;  3QK8 A;  3DOR A;  4ZDC A;  1EY3 A;  3HLN 1;  3OME A;  3H0S A;  3LAO A;  4FN8 A;  5DUF A;  3PGQ A;  3HE2 A;  4OMR A;  4ELX A;  3I47 A;  3Q0G A;  1UYV A;  4ZDF A;  1DCI A;  3MT6 A;  4K3W A;  4QIJ A;  2ZQR A;  2X24 A;  2Q35 A;  2X58 A;  4QII A;  3ZW8 A;  3T88 A;  1EF8 A;  5E0S A;  1UYT A;  1N6F A;  3ZWB A;  3TVW A;  2DUB A;  2GTR A;  3PZK A;  1UIY A;  4I4Z A;  4L8K A;  4FND A;  2D3T A;  3NJD A;  5INI A;  3R6H A;  5DL1 A;  4ELS A;  3M6N A;  2VSU F;  4ZDE A;  4EML A;  3QXZ A;  4K29 A;  3Q7H A;  4ZU2 A;  3GLM A;  2FZS A;  5CTC A;  4ZDD A;  3PE8 A;  4FB8 A;  3R9S A;  3P2L A;  3HIN A;  2VSS F;  4HC8 A;  4OLQ A;  2BZR A;  3ZWA A;  3LKE A;  4Q1I A;  3U9R B;  3MOY A;  2HW5 A;  1DUB A;  4FNB A;  3H0J A;  3SLL A;  2J5G A;  3V5I A;  5C9G A;  5DTW A;  5ING A;  2Q2X A;  3P5M A;  3NJB A;  3MYB A;  1W2X A;  4I42 A;  4Q0G A;  4U1A A;  3TV5 A;  3T89 A;  3QMJ A;  3H02 A;  1ON3 A;  4DI1 A;  2CE3 A;  3Q0J A;  3T3W A;  3KQF A;  2VSS E;  3OT6 A;  3PEA A;  1JXZ A;  1Y7O A;  4JCQ A;  2W3P A;  3BF0 A;  1XNY A;  1XNW A;  3BPT A;  2ZL4 A;  4EMP A;  1WDL A;  4JOT A;  4RYF A;  1PJH A;  1Q51 A;  3U9T B;  1SG4 A;  4RCN A;  2F6Q A;  5G1Q A;  4JYL A;  1N6D A;  1PIX A;  1J7X A;  3T8A A;  5E0S H;  1XO6 A;  5KJP A;  4HDT A;  2J5G D;  4U0H A;  2ZL2 A;  4JSB A;  3KTI A;  1XNV A;  3P85 A;  4J2U A;  3IAV A;  4JFC A;  2A7S A;  1YG8 A;  4NNQ A;  1NZY B;  3RST A;  4JYJ A;  3ZW9 A;  3HP0 A;  4IZB A;  3TT7 A;  2DEO A;  4B3I A;  3KTJ A;  5G1S A;  1WZ8 A;  3GF3 A;  3H81 A;  1O8U A;  4WCZ A;  4L6W A;  1HZD A;  1RJN A;  1NZY A;  3QKA A;  5DZK A;  3DJA A;  2VX2 A;  5DUC A;  2CBY A;  4Z0M A;  3TT6 A;  4KD6 A;  5DU6 A;  4JJT A;  2NP9 A;  4LK5 A;  3QRE A;  4ZDB A;  5IKL B;  3QWD A;  5MGB A;  2QQ3 A;  3RSI A;  3H0U A;  3KTK A;  3STA A;  3TRR A;  1K39 A;  4U0G A;  5CTB A;  4GHN A;  3L3S A;  1SZO A;  4JCR A;  5FUS A;  2A81 A;  1OD4 A;  1YG6 A;  4KWB A;  4YLH A;  4HNK A;  3T8B A;  4WZ8 B;  4WYO B;  1FC7 A;  4ASI A;  4JCS A;  1FCF A;  2VSU A;  3U9S B;  4RYF H;  4QFE A;  2A7K A;  3KTG A;  3IBB A;  4NAR A;  3M6M A;  2FW2 A;  2F9Y B;  3Q1T A;  3IB9 A;  2VSU C;  1Q52 A;  4MXI A;  3TVU A;  2UZF A;  3FF6 A;  3V5E A;  2VSS A;  4JVT A;  1N6E A;  5DKP A;  4IZD A;  1MJ3 A;  4MOU A;  3H0Q A;  3GKB A;  1ON9 A;  2YJG A;  3MFM A;  5HUQ A;  1UYR A;  1UYS A;  4G2R A;  4GM2 A;  4MI2 A;  4FN7 A;  4JWV A;  2F9Y A;  3N6R B;  3TLF A;  4NEK A;  1VRG A;  4JCT A;  3BPP A;  4FZW A;  1FC9 A;  3G64 A;  3FDU A;  4K2N A;  3KTH A;  2WTB A;  2Q34 A;  5KDR B;  1TYF A;  4FZW C;  1XX4 A;  3K50 A;  5DZK H;  2ZL0 A;  5DU4 A;  5JBW A;  2C8T A;  4KPK A;  2ZL3 A;  2J5I B;  2EJ5 A;  4I52 A;  1EF9 A;  3ZWC A;  1OD2 A;  3ISA A;  3TZ3 A;  4KNP A;  5DU8 A;  4EMM A;  5KDR A;  4U0G H;  5E0N X;  1HNU A;  2F6I A;  2J5I I;  4B3J A;  1TG6 A;  4U18 A;  4B3H A;  3HRX A;  3R0O A;  3SWX A;  1X0U A;  2J5I A;  2IEX A;  2J5S A;  5C90 A;  3OC7 A;  1HNO A;  3QYR A;  3K8X A;  1FC6 A;  2F9I B;  5FIF A;  2VRE A;  4U19 A;  1WDM A;  4OG1 A;  4FJW D;  3QXI A;  2PPY A;  3VIV A;  3R9T A;  3WG5 A;  2ZQQ A;  3JU1 A;  5DTP A;  5G1R A;  4ELW A;  2PBP A;  3RRV A;  2VSU E;  1WDK A;  2PG8 A;  3R9Q A;  3GF7 A;  5INF A; 
#chains in the Genus database with same CATH homology
 1RJM A;  3BEZ A;  3GMA A;  1K32 A;  2F9I A;  3ST9 A;  4IZC A;  4F47 A;  2FBM A;  5JBX A;  3TDC A;  3QK8 A;  3DOR A;  4ZDC A;  1EY3 A;  3HLN 1;  3OME A;  3H0S A;  3LAO A;  4FN8 A;  5DUF A;  3PGQ A;  3HE2 A;  4OMR A;  4ELX A;  3I47 A;  3Q0G A;  1UYV A;  4ZDF A;  1DCI A;  3MT6 A;  4K3W A;  4QIJ A;  2ZQR A;  2X24 A;  2Q35 A;  2X58 A;  4QII A;  3ZW8 A;  3T88 A;  1EF8 A;  5E0S A;  1UYT A;  1N6F A;  3ZWB A;  3TVW A;  2DUB A;  2GTR A;  3PZK A;  1UIY A;  4I4Z A;  4L8K A;  4FND A;  2D3T A;  3NJD A;  5INI A;  3R6H A;  5DL1 A;  4ELS A;  3M6N A;  2VSU F;  4ZDE A;  4EML A;  3QXZ A;  4K29 A;  3Q7H A;  4ZU2 A;  3GLM A;  2FZS A;  5CTC A;  4ZDD A;  3PE8 A;  4FB8 A;  3R9S A;  3P2L A;  3HIN A;  2VSS F;  4HC8 A;  4OLQ A;  2BZR A;  3ZWA A;  3LKE A;  4Q1I A;  3U9R B;  3MOY A;  2HW5 A;  1DUB A;  4FNB A;  3H0J A;  3SLL A;  2J5G A;  3V5I A;  5C9G A;  5DTW A;  5ING A;  2Q2X A;  3P5M A;  3NJB A;  3MYB A;  1W2X A;  4I42 A;  4Q0G A;  4U1A A;  3TV5 A;  3T89 A;  3QMJ A;  3H02 A;  1ON3 A;  4DI1 A;  2CE3 A;  3Q0J A;  3T3W A;  3KQF A;  2VSS E;  3OT6 A;  3PEA A;  1JXZ A;  1Y7O A;  4JCQ A;  2W3P A;  3BF0 A;  1XNY A;  1XNW A;  3BPT A;  2ZL4 A;  4EMP A;  1WDL A;  4JOT A;  4RYF A;  1PJH A;  1Q51 A;  3U9T B;  1SG4 A;  4RCN A;  2F6Q A;  5G1Q A;  4JYL A;  1N6D A;  1PIX A;  1J7X A;  3T8A A;  5E0S H;  1XO6 A;  5KJP A;  4HDT A;  2J5G D;  4U0H A;  2ZL2 A;  4JSB A;  3KTI A;  1XNV A;  3P85 A;  4J2U A;  3IAV A;  4JFC A;  2A7S A;  1YG8 A;  4NNQ A;  1NZY B;  3RST A;  4JYJ A;  3ZW9 A;  3HP0 A;  4IZB A;  3TT7 A;  2DEO A;  4B3I A;  3KTJ A;  5G1S A;  1WZ8 A;  3GF3 A;  3H81 A;  1O8U A;  4WCZ A;  4L6W A;  1HZD A;  1RJN A;  1NZY A;  3QKA A;  5DZK A;  3DJA A;  2VX2 A;  5DUC A;  2CBY A;  4Z0M A;  3TT6 A;  4KD6 A;  5DU6 A;  4JJT A;  2NP9 A;  4LK5 A;  3QRE A;  4ZDB A;  5IKL B;  3QWD A;  5MGB A;  2QQ3 A;  3RSI A;  3H0U A;  3KTK A;  3STA A;  3TRR A;  1K39 A;  4U0G A;  5CTB A;  4GHN A;  3L3S A;  1SZO A;  4JCR A;  5FUS A;  2A81 A;  1OD4 A;  1YG6 A;  4KWB A;  4YLH A;  4HNK A;  3T8B A;  4WZ8 B;  4WYO B;  1FC7 A;  4ASI A;  4JCS A;  1FCF A;  2VSU A;  3U9S B;  4RYF H;  4QFE A;  2A7K A;  3KTG A;  3IBB A;  4NAR A;  3M6M A;  2FW2 A;  2F9Y B;  3Q1T A;  3IB9 A;  2VSU C;  1Q52 A;  4MXI A;  3TVU A;  2UZF A;  3FF6 A;  3V5E A;  2VSS A;  4JVT A;  1N6E A;  5DKP A;  4IZD A;  1MJ3 A;  4MOU A;  3H0Q A;  3GKB A;  1ON9 A;  2YJG A;  3MFM A;  5HUQ A;  1UYR A;  1UYS A;  4G2R A;  4GM2 A;  4MI2 A;  4FN7 A;  4JWV A;  2F9Y A;  3N6R B;  3TLF A;  4NEK A;  1VRG A;  4JCT A;  3BPP A;  4FZW A;  1FC9 A;  3G64 A;  3FDU A;  4K2N A;  3KTH A;  2WTB A;  2Q34 A;  5KDR B;  1TYF A;  4FZW C;  1XX4 A;  3K50 A;  5DZK H;  2ZL0 A;  5DU4 A;  5JBW A;  2C8T A;  4KPK A;  2ZL3 A;  2J5I B;  2EJ5 A;  4I52 A;  1EF9 A;  3ZWC A;  1OD2 A;  3ISA A;  3TZ3 A;  4KNP A;  5DU8 A;  4EMM A;  5KDR A;  4U0G H;  5E0N X;  1HNU A;  2F6I A;  2J5I I;  4B3J A;  1TG6 A;  4U18 A;  4B3H A;  3HRX A;  3R0O A;  3SWX A;  1X0U A;  2J5I A;  2IEX A;  2J5S A;  5C90 A;  3OC7 A;  1HNO A;  3QYR A;  3K8X A;  1FC6 A;  2F9I B;  5FIF A;  2VRE A;  4U19 A;  1WDM A;  4OG1 A;  4FJW D;  3QXI A;  2PPY A;  3VIV A;  3R9T A;  3WG5 A;  2ZQQ A;  3JU1 A;  5DTP A;  5G1R A;  4ELW A;  2PBP A;  3RRV A;  2VSU E;  1WDK A;  2PG8 A;  3R9Q A;  3GF7 A;  5INF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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