5CVWA

Crystal structure of rtx domain block v of adenylate cyclase toxin from bordetella pertussis
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
150
structure length
150
Chain Sequence
GSARDDVLIGDAGANVLNGLAGNDVLSGGAGDDVLLGDEGSDLLSGDAGNDDLFGGQGDDTYLFGVGYGHDTIYESGGGHDTIRINAGADQLWFARQGNDLEIRILGTDDALTVHDWYRDADHRVEIIHAANQAVDQAGIEKLVEAMAQY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Toxin
molecule keywords Bifunctional hemolysin/adenylate cyclase
publication title Calcium-Driven Folding of RTX Domain beta-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
pubmed doi rcsb
source organism Bordetella pertussis (strain atcc 9797 / dsm 5571 / nctc 10739 / 18323)
total genus 49
structure length 150
sequence length 150
ec nomenclature ec 4.6.1.1: Adenylate cyclase.
pdb deposition date 2015-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00353 HemolysinCabind RTX calcium-binding nonapeptide repeat (4 copies)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.150.10.10 Mainly Beta 2 Solenoid Alkaline Protease, subunit P, domain 1 Serralysin-like metalloprotease, C-terminal 5cvwA00
1GO7P 2AGMA 2ZJ7A 2QUBA 2ZJ6A 4I35A 5CVWA 1OM8A 3U1RA 1H71P 3A70A 2QUAA 1GO8P 1O0TA 1G9KA 3HDAP 2YO0A 5D7WA 1P9HA 1JIWP 1SRPA 3S6LA 1K7IA 3LAAA 3WP8A 5CXLA 3HB2P 2XQHA 2Z8ZA 1OM6A 1AF0A 1SMPA 3HBUP 3VI1A 2ZVDA 3ULTA 1K7QA 2ML2A 3LA9A 1O0QA 3A6ZA 1OMJA 3NTNA 2YO1A 1OM7A 1SATA 2Z8XA 3HBVP 1KAPP 1K7GA 1AKLA
chains in the Genus database with same CATH superfamily
1GO7P 2AGMA 2ZJ7A 2QUBA 2ZJ6A 4I35A 5CVWA 1OM8A 3U1RA 1H71P 3A70A 2QUAA 1GO8P 1O0TA 1G9KA 3HDAP 2YO0A 5D7WA 1P9HA 1JIWP 1SRPA 3S6LA 1K7IA 3LAAA 3WP8A 5CXLA 3HB2P 2XQHA 2Z8ZA 1OM6A 1AF0A 1SMPA 3HBUP 3VI1A 2ZVDA 3ULTA 1K7QA 2ML2A 4DT5A 3LA9A 1O0QA 3A6ZA 1OMJA 3NTNA 2YO1A 1OM7A 1SATA 2Z8XA 3HBVP 1KAPP 1K7GA 1AKLA
chains in the Genus database with same CATH topology
1GO7P 2AGMA 2ZJ7A 2QUBA 2ZJ6A 4I35A 5CVWA 1OM8A 3U1RA 1H71P 3A70A 2QUAA 1GO8P 1O0TA 1G9KA 3HDAP 2YO0A 5D7WA 1P9HA 1JIWP 1SRPA 3S6LA 1K7IA 3LAAA 3WP8A 5CXLA 3HB2P 2XQHA 2Z8ZA 1OM6A 1AF0A 1SMPA 3HBUP 3VI1A 2ZVDA 3ULTA 1K7QA 2ML2A 3LA9A 1O0QA 3A6ZA 1OMJA 3NTNA 2YO1A 1OM7A 1SATA 2Z8XA 3HBVP 1KAPP 1K7GA 1AKLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GO7 P;  2AGM A;  2ZJ7 A;  2QUB A;  2ZJ6 A;  4I35 A;  5CVW A;  1OM8 A;  3U1R A;  1H71 P;  3A70 A;  2QUA A;  1GO8 P;  1O0T A;  1G9K A;  3HDA P;  2YO0 A;  5D7W A;  1P9H A;  1JIW P;  1SRP A;  3S6L A;  1K7I A;  3LAA A;  3WP8 A;  5CXL A;  3HB2 P;  2XQH A;  2Z8Z A;  1OM6 A;  1AF0 A;  1SMP A;  3HBU P;  3VI1 A;  2ZVD A;  3ULT A;  1K7Q A;  2ML2 A;  3LA9 A;  1O0Q A;  3A6Z A;  1OMJ A;  3NTN A;  2YO1 A;  1OM7 A;  1SAT A;  2Z8X A;  3HBV P;  1KAP P;  1K7G A;  1AKL A; 
#chains in the Genus database with same CATH topology
 1GO7 P;  2AGM A;  2ZJ7 A;  2QUB A;  2ZJ6 A;  4I35 A;  5CVW A;  1OM8 A;  3U1R A;  1H71 P;  3A70 A;  2QUA A;  1GO8 P;  1O0T A;  1G9K A;  3HDA P;  2YO0 A;  5D7W A;  1P9H A;  1JIW P;  1SRP A;  3S6L A;  1K7I A;  3LAA A;  3WP8 A;  5CXL A;  3HB2 P;  2XQH A;  2Z8Z A;  1OM6 A;  1AF0 A;  1SMP A;  3HBU P;  3VI1 A;  2ZVD A;  3ULT A;  1K7Q A;  2ML2 A;  4DT5 A;  3LA9 A;  1O0Q A;  3A6Z A;  1OMJ A;  3NTN A;  2YO1 A;  1OM7 A;  1SAT A;  2Z8X A;  3HBV P;  1KAP P;  1K7G A;  1AKL A; 
#chains in the Genus database with same CATH homology
 1GO7 P;  2AGM A;  2ZJ7 A;  2QUB A;  2ZJ6 A;  4I35 A;  5CVW A;  1OM8 A;  3U1R A;  1H71 P;  3A70 A;  2QUA A;  1GO8 P;  1O0T A;  1G9K A;  3HDA P;  2YO0 A;  5D7W A;  1P9H A;  1JIW P;  1SRP A;  3S6L A;  1K7I A;  3LAA A;  3WP8 A;  5CXL A;  3HB2 P;  2XQH A;  2Z8Z A;  1OM6 A;  1AF0 A;  1SMP A;  3HBU P;  3VI1 A;  2ZVD A;  3ULT A;  1K7Q A;  2ML2 A;  3LA9 A;  1O0Q A;  3A6Z A;  1OMJ A;  3NTN A;  2YO1 A;  1OM7 A;  1SAT A;  2Z8X A;  3HBV P;  1KAP P;  1K7G A;  1AKL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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