5D3WA

Crystal structure of the p-rex1 ph domain with sulfate bound
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
151
Chain Sequence
b'GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 45
structure length 151
sequence length 166
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3wA00
2J0KA 3VIAA 4KHAA 5D3VA 2AEHA 2VRWB 1P3RA 1WJMA 1LB1A 2UZSA 1WG7A 3PEGA 3SYXA 3D8EA 1N3HA 5J3TA 4HAZB 4HB4B 1ZVRA 1ZSQA 1RRPB 5C79A 2RNRB 5HE2A 4HHVA 5LONB 5KCVA 4GN1A 2UZRA 1H10A 3CXBB 2H7EA 1UNRA 4F7GA 4DX8A 4A6KA 2HTHB 2AL6A 3N7CA 1U5GA 2DHIA 2KGXB 1P6SA 4GPTB 1W1GA 1W1HA 2N0YA 3T06A 5HE0A 1GG3A 5DIFB 4KVGB 3AJ4A 1V5MA 5DH9B 2BCJA 2LOXA 2M14A 4GXBA 4C0AA 1Y19B 2DKQA 3FM8C 4CYEA 1BWNA 2LKOA 1PLSA 5DHAB 1ISNA 2K2JA 1V5UA 1EGXA 4EJNA 2DFKA 1XCGA 4EMOA 1FHWA 1UNQA 5HE3A 2EMTA 2CY5A 3QWMA 1M7EA 2ELBA 5KQ1A 1W1DA 1QC6A 2W2WA 1I7AA 1DDWA 4CHMA 1K5DB 3KY9A 4MY6A 1FOEA 1AWEA 2DA0A 3TW1A 3ODOA 4DX90 2ADZA 1PMSA 1U27A 1Y5OA 2XQNM 1GC7A 2MKRA 2LYDA 1SHCA 2Y8FA 2DYQA 5GOWB 1Q67A 3O96A 2K2UA 3G9WA 2D9VA 5D3XA 3ULCA 3PSCA 2HE7A 1TXDA 3M1IB 2DLWA 4A5KA 1KZ7A 3SUZA 3KRXA 2KUPA 2GCJA 2ROZB 4DBBA 3FSSA 3F0WA 5LOPB 3PP2A 2CY4A 1UPQA 3WYFB 5C5BA 3PZDA 2FJLA 3MDBC 4HB2B 3MPXA 1UEFA 2RGNB 1MAIA 1U5EA 4HAVB 4IOYX 2I1JA 1TJ6A 1V5PA 4HB0B 1NU2A 2YS5A 2L2IA 2VSZA 2EC1A 1NI2A 1XD4A 2LULA 4WVFB 1KZGA 2MWNB 2R09A 4NSWA 1U5FA 1TQZA 2RVBB 1QQGA 4WJ7A 1X11A 3TFMA 1FAOA 1X05A 1MIZB 4HDOA 2COFA 1MK7B 5D3YA 4PQ0A 1MPHA 3ML4A 2E2XA 4IAPA 2Q13A 3FEHA 3PVUA 4A6FB 4HATB 2DN6A 1I2HA 5C16A 4P7IA 3BINA 2N23A 3IVFA 4MT7A 2GJYA 1MKEA 2R0DA 1ZC3B 2DX1A 2X18A 1KI1B 3A98B 5CLLB 4ZRKA 2P0DA 3ODXA 4F7HA 5CLQB 1OQNA 4KHBB 1J19A 2DKPA 2P8VA 4K2OA 5FI0A 2KCJA 2NMBA 2D10A 2EJ8A 1SGHA 4K2PA 3TCAA 1OMWA 1U2BA 4A6FA 1RJ2A 2RUKB 4HAUB 1BAKA 2Y8GA 3HW2B 1EVHA 4HDQA 1FHXA 2J0JA 4Z2MB 4CHJA 3PVWA 4EKUA 4GMXB 1BTNA 2P0HA 2DTCA 1WGQA 3F5RA 2MFQA 1V61A 3X23A 4HAYB 2M38A 3ZDTA 2Z0QA 2IYBA 2J0MA 3PVLA 3HK0A 2D9YA 2H7DA 2D11A 3KZ1A 5D27A 4TYZA 2QKMA 2CRFA 2I1KA 2D9WA 2YT0A 2COAA 3AU4A 1DYNA 2Z0PA 2OQBA 2MDXA 4HB3B 1V88A 1XX0A 1PFJA 3RCPA 2YSZA 1M7RA 1E5WA 4Z2NA 1U5DA 1WVHA 1NTVA 1Z87A 1X1GA 1MIXA 2OTXA 2NZ8B 5L81A 4K81A 3QBVB 3WA0A 2LG1A 2Y7BA 4D0NB 2QKLA 3ZVRA 1NTYA 2EMSA 3D8FA 2PZ1A 3PG7A 4BBKA 1DDMA 4ZRJA 1UPRA 2K00A 2V76A 1J0WA 2COCA 4YL8A 3D8DA 3GYPA 1XKEA 4TKNA 1K5GB 3TO1A 2YVCA 3GYOA 1EAZA 4HAXB 3U7DA 4MK0A 5J3YA 2DX5A 3DXCA 2L1CA 1P5TA 4XWXA 4YONA 3KRWA 5DI9B 2IFSA 2W2XC 1FB8A 1ZM0A 2YF0A 4HAWB 2ELAA 2UVMA 4A6HA 2I5CA 2YS3A 1OY2A 4GMVA 1DDVA 4KHOA 1FGZA 4B6HA 3DXDA 4Y94A 3BJIA 1B55A 1MK9B 1V89A 3TVVA 3V5WA 3A8PA 5JHGA 1FGYA 3OANA 2YS1A 3SO6A 5HE1A 2VKIA 4DXAB 2CAYA 2LOZA 2G35A 1WGUA 2DHKA 1XR0B 2D9ZA 2RLOA 3P6AA 2GCLA 3LJUX 5JHHA 2ZPYA 2DHJA 3AU5A 2D4QA 2P0FA 2JP2A 1ZC4B 3A8QA 3SNHA 3HQCA 5FI1A 3KSYA 1FHOA 1GC6A 2GS0A 5J3QA 1BTKA 5C5BB 1UNPA 3VOQA 1WI1A 1LW3A 5JLJB 5D3WA 1DROA 4GZUA 1X1FA 2ROVA 3U8ZA 3ULBA 4K17A 1U29A 3ODWA 4NY0A 4WSFA 3QIJA 5JP4A 2W2XD 2J59M 4H8SA 5C6RA 1X86A 3SV1A 1WJ1A 2YT1A 4PNKA 3NSUA 2Z0OA 2D2QA 3DXEA 4F7UP 3CIKA 5DHFB 5KQ4A 2I5FA 2YRYA 2DYNA 1DBHA 4KAXB 1XODA 3P7ZA 5EFXA 2CODA 1IRSA 1H4RA 2RSGA 4L6EA 4IFSA 3UZTA 2D9XA 4ZRIA 1EF1A 1AQCA
chains in the Genus database with same CATH superfamily
2J0KA 4D6WA 3VIAA 4KHAA 5D3VA 3HIEA 2AEHA 2VRWB 1P3RA 1WJMA 1LB1A 2UZSA 1WG7A 3PEGA 2Z14A 3SYXA 3D8EA 1N3HA 5J3TA 4HAZB 4HB4B 1ZVRA 2Z59A 1ZSQA 1RRPB 3U12A 5C79A 2RNRB 5HE2A 5M4YB 4HHVA 5LONB 5KCVA 4GN1A 2UZRA 1H10A 3CXBB 2H7EA 1UNRA 4F7GA 4DX8A 4A6KA 2HTHB 2AL6A 3N7CA 1U5GA 2K49A 2DHIA 2KGXB 3NW8A 1P6SA 4GPTB 1W1GA 1W1HA 2N0YA 3T06A 5HE0A 1GG3A 5DIFB 4KVGB 3AJ4A 1V5MA 5DH9B 2BCJA 2LOXA 5LG4B 2M14A 4GXBA 4C0AA 1Y19B 2DKQA 3FM8C 4CYEA 1BWNA 2LKOA 1PLSA 5DHAB 1ISNA 2K2JA 1V5UA 5I2MA 4EJNA 2DFKA 1EGXA 1XCGA 4EMOA 1FHWA 5I2SA 1UNQA 5HE3A 2EMTA 2CY5A 3QWMA 1M7EA 2ELBA 5KQ1A 1W1DA 1QC6A 2W2WA 1I7AA 1DDWA 4CHMA 1K5DB 3A58A 3KY9A 4MY6A 1FOEA 1AWEA 2DA0A 3TW1A 3OHMB 3NWDA 3ODOA 4DX90 2ADZA 1PMSA 1U27A 1Y5OA 2XQNM 2Z4DA 1GC7A 2MKRA 2LYDA 1SHCA 2Y8FA 2DYQA 5GOWB 1Q67A 3O96A 4OSNA 3G9WA 2K2UA 2D9VA 5D3XA 3ULCA 3PSCA 2HE7A 1TXDA 3M1IB 2DLWA 4A5KA 1KZ7A 3SUZA 3KRXA 2KUPA 2GCJA 2ROZB 4DBBA 3FSSA 5IRSA 1ZYIA 3F0WA 5LOPB 3PP2A 2CY4A 1UPQA 3WYFB 5C5BA 3PZDA 2FJLA 3MDBC 4HB2B 3MPXA 1UEFA 2RGNB 1MAIA 1U5EA 4HAVB 4IOYX 2I1JA 1TJ6A 1V5PA 4HB0B 1NU2A 2YS5A 2L2IA 2VSZA 2EC1A 2YT2A 1NI2A 1XD4A 4QJ5B 2LULA 4WVFB 1KZGA 2MWNB 2R09A 4NSWA 1U5FA 1TQZA 2RVBB 1QQGA 4WJ7A 1X11A 3TFMA 1FAOA 1X05A 1MIZB 4HDOA 2COFA 1MK7B 5D3YA 4PQ0A 1MPHA 3ML4A 2E2XA 4IAPA 2Q13A 3FEHA 3PVUA 4A6FB 3NWAA 4HATB 2DN6A 1I2HA 5C16A 4P7IA 4QXAB 3BINA 2N23A 3IVFA 4MT7A 2GJYA 1MKEA 2R0DA 1ZC3B 3B77A 2DX1A 2X18A 1KI1B 3A98B 5CLLB 4ZRKA 2P0DA 3ODXA 4F7HA 5CLQB 1OQNA 4DIXA 2FJUB 2KIEA 4KHBB 1J19A 2DKPA 2P8VA 4K2OA 5FI0A 2KCJA 2NMBA 4QJ4B 2D10A 2EJ8A 1SGHA 4K2PA 3TCAA 1OMWA 1U2BA 2Z13A 4A6FA 1RJ2A 2RUKB 4HAUB 1BAKA 2Y8GA 4L1RA 3HW2B 1EVHA 4HDQA 1FHXA 2J0JA 4Z2MB 4CHJA 3PVWA 4EKUA 4GMXB 1BTNA 2P0HA 2DTCA 3HSAA 1WGQA 3F5RA 3NWFA 2MFQA 1V61A 3X23A 4HAYB 2M38A 4KHBA 4OT1A 3ZDTA 2Z0QA 2IYBA 4CSQA 2J0MA 3PVLA 3HK0A 2D9YA 2H7DA 2D11A 3KZ1A 5D27A 4TYZA 2QKMA 2CRFA 2KIGA 2I1KA 2D9WA 2GUMA 2YT0A 2COAA 3AU4A 1DYNA 2Z0PA 2OQBA 2MDXA 4HB3B 1V88A 1XX0A 1PFJA 3RCPA 4GNKB 2YSZA 1M7RA 1E5WA 4Z2NA 1U5DA 1WVHA 1NTVA 1Z87A 2K8EA 1X1GA 1MIXA 2OTXA 2NZ8B 5L81A 4K81A 3QBVB 3WA0A 2LG1A 2Y7BA 4D0NB 2QKLA 3ZVRA 1NTYA 2EMSA 3D8FA 2PZ1A 3PG7A 4BBKA 1DDMA 4ZRJA 1UPRA 2K00A 2V76A 1J0WA 2COCA 4YL8A 3D8DA 3GYPA 1XKEA 4TKNA 1K5GB 3TO1A 2ZKMX 2YVCA 3GYOA 1EAZA 4HAXB 3U7DA 4MK0A 5J3YA 2DX5A 2KUQA 3DXCA 2L1CA 1P5TA 3FVCA 4XWXA 4YONA 3KRWA 2NBVA 5DI9B 2IFSA 2W2XC 1FB8A 1ZM0A 2YF0A 4HAWB 2ELAA 2UVMA 4A6HA 2I5CA 2YS3A 1OY2A 4GMVA 1DDVA 4KHOA 1MI1A 1FGZA 4B6HA 3DXDA 4Y94A 3BJIA 1B55A 1MK9B 1V89A 3TVVA 3V5WA 3A8PA 5JHGA 1FGYA 3OANA 2YS1A 4HSIA 3SO6A 5HE1A 2VKIA 4DXAB 2CAYA 2LOZA 2G35A 1WGUA 2DHKA 1XR0B 2D9ZA 2RLOA 3P6AA 2GCLA 3LJUX 5JHHA 2ZPYA 2DHJA 3AU5A 2KR0A 2D4QA 2P0FA 2JP2A 1ZC4B 3A8QA 3SNHA 3HQCA 5FI1A 3KSYA 1FHOA 1GC6A 2GS0A 5J3QA 1BTKA 4GOUA 5C5BB 1UNPA 3VOQA 1WI1A 1LW3A 5JLJB 5D3WA 1DROA 4GZUA 1X1FA 2ROVA 3U8ZA 3ULBA 3DCXA 4K17A 1U29A 3ODWA 4NY0A 4WSFA 3QIJA 5JP4A 2W2XD 2J59M 4H8SA 5C6RA 1T77A 1X86A 3SV1A 1WJ1A 2YT1A 2RRFA 4PNKA 3NSUA 2Z0OA 2D2QA 3DXEA 4F7UP 3CIKA 5DHFB 5KQ4A 2I5FA 2YRYA 2DYNA 1DBHA 4QJ3B 4KAXB 1XODA 3P7ZA 5EFXA 2CODA 1IRSA 2R2YA 1H4RA 2RSGA 4L6EA 4IFSA 3UZTA 2D9XA 4ZRIA 1EF1A 1AQCA
chains in the Genus database with same CATH topology
2J0KA 3VIAA 4KHAA 5D3VA 2AEHA 2VRWB 1P3RA 1WJMA 1LB1A 2UZSA 1WG7A 3PEGA 3SYXA 3D8EA 1N3HA 5J3TA 4HAZB 4HB4B 1ZVRA 1ZSQA 1RRPB 5C79A 2RNRB 5HE2A 4HHVA 5LONB 5KCVA 4GN1A 2UZRA 1H10A 3CXBB 2H7EA 1UNRA 4F7GA 4DX8A 4A6KA 2HTHB 2AL6A 3N7CA 1U5GA 2DHIA 2KGXB 1P6SA 4GPTB 1W1GA 1W1HA 2N0YA 3T06A 5HE0A 1GG3A 5DIFB 4KVGB 3AJ4A 1V5MA 5DH9B 2BCJA 2LOXA 2M14A 4GXBA 4C0AA 1Y19B 2DKQA 3FM8C 4CYEA 1BWNA 2LKOA 1PLSA 5DHAB 1ISNA 2K2JA 1V5UA 1EGXA 4EJNA 2DFKA 1XCGA 4EMOA 1FHWA 1UNQA 5HE3A 2EMTA 2CY5A 3QWMA 1M7EA 2ELBA 5KQ1A 1W1DA 1QC6A 2W2WA 1I7AA 1DDWA 4CHMA 1K5DB 3KY9A 4MY6A 1FOEA 1AWEA 2DA0A 3TW1A 3ODOA 4DX90 2ADZA 1PMSA 1U27A 1Y5OA 2XQNM 1GC7A 2MKRA 2LYDA 1SHCA 2Y8FA 2DYQA 5GOWB 1Q67A 3O96A 2K2UA 3G9WA 2D9VA 5D3XA 3ULCA 3PSCA 2HE7A 1TXDA 3M1IB 2DLWA 4A5KA 1KZ7A 3SUZA 3KRXA 2KUPA 2GCJA 2ROZB 4DBBA 3FSSA 3F0WA 5LOPB 3PP2A 2CY4A 1UPQA 3WYFB 5C5BA 3PZDA 2FJLA 3MDBC 4HB2B 3MPXA 1UEFA 2RGNB 1MAIA 1U5EA 4HAVB 4IOYX 2I1JA 1TJ6A 1V5PA 4HB0B 1NU2A 2YS5A 2L2IA 2VSZA 2EC1A 1NI2A 1XD4A 2LULA 4WVFB 1KZGA 2MWNB 2R09A 4NSWA 1U5FA 1TQZA 2RVBB 1QQGA 4WJ7A 1X11A 3TFMA 1FAOA 1X05A 1MIZB 4HDOA 2COFA 1MK7B 5D3YA 4PQ0A 1MPHA 3ML4A 2E2XA 4IAPA 2Q13A 3FEHA 3PVUA 4A6FB 4HATB 2DN6A 1I2HA 5C16A 4P7IA 3BINA 2N23A 3IVFA 4MT7A 2GJYA 1MKEA 2R0DA 1ZC3B 2DX1A 2X18A 1KI1B 3A98B 5CLLB 4ZRKA 2P0DA 3ODXA 4F7HA 5CLQB 1OQNA 4KHBB 1J19A 2DKPA 2P8VA 4K2OA 5FI0A 2KCJA 2NMBA 2D10A 2EJ8A 1SGHA 4K2PA 3TCAA 1OMWA 1U2BA 4A6FA 1RJ2A 2RUKB 4HAUB 1BAKA 2Y8GA 3HW2B 1EVHA 4HDQA 1FHXA 2J0JA 4Z2MB 4CHJA 3PVWA 4EKUA 4GMXB 1BTNA 2P0HA 2DTCA 1WGQA 3F5RA 2MFQA 1V61A 3X23A 4HAYB 2M38A 3ZDTA 2Z0QA 2IYBA 2J0MA 3PVLA 3HK0A 2D9YA 2H7DA 2D11A 3KZ1A 5D27A 4TYZA 2QKMA 2CRFA 2I1KA 2D9WA 2YT0A 2COAA 3AU4A 1DYNA 2Z0PA 2OQBA 2MDXA 4HB3B 1V88A 1XX0A 1PFJA 3RCPA 2YSZA 1M7RA 1E5WA 4Z2NA 1U5DA 1WVHA 1NTVA 1Z87A 1X1GA 1MIXA 2OTXA 2NZ8B 5L81A 4K81A 3QBVB 3WA0A 2LG1A 2Y7BA 4D0NB 2QKLA 3ZVRA 1NTYA 2EMSA 3D8FA 2PZ1A 3PG7A 4BBKA 1DDMA 4ZRJA 1UPRA 2K00A 2V76A 1J0WA 2COCA 4YL8A 3D8DA 3GYPA 1XKEA 4TKNA 1K5GB 3TO1A 2YVCA 3GYOA 1EAZA 4HAXB 3U7DA 4MK0A 5J3YA 2DX5A 3DXCA 2L1CA 1P5TA 4XWXA 4YONA 3KRWA 5DI9B 2IFSA 2W2XC 1FB8A 1ZM0A 2YF0A 4HAWB 2ELAA 2UVMA 4A6HA 2I5CA 2YS3A 1OY2A 4GMVA 1DDVA 4KHOA 1FGZA 4B6HA 3DXDA 4Y94A 3BJIA 1B55A 1MK9B 1V89A 3TVVA 3V5WA 3A8PA 5JHGA 1FGYA 3OANA 2YS1A 3SO6A 5HE1A 2VKIA 4DXAB 2CAYA 2LOZA 2G35A 1WGUA 2DHKA 1XR0B 2D9ZA 2RLOA 3P6AA 2GCLA 3LJUX 5JHHA 2ZPYA 2DHJA 3AU5A 2D4QA 2P0FA 2JP2A 1ZC4B 3A8QA 3SNHA 3HQCA 5FI1A 3KSYA 1FHOA 1GC6A 2GS0A 5J3QA 1BTKA 5C5BB 1UNPA 3VOQA 1WI1A 1LW3A 5JLJB 5D3WA 1DROA 4GZUA 1X1FA 2ROVA 3U8ZA 3ULBA 4K17A 1U29A 3ODWA 4NY0A 4WSFA 3QIJA 5JP4A 2W2XD 2J59M 4H8SA 5C6RA 1X86A 3SV1A 1WJ1A 2YT1A 4PNKA 3NSUA 2Z0OA 2D2QA 3DXEA 4F7UP 3CIKA 5DHFB 5KQ4A 2I5FA 2YRYA 2DYNA 1DBHA 4KAXB 1XODA 3P7ZA 5EFXA 2CODA 1IRSA 1H4RA 2RSGA 4L6EA 4IFSA 3UZTA 2D9XA 4ZRIA 1EF1A 1AQCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J0K A;  3VIA A;  4KHA A;  5D3V A;  2AEH A;  2VRW B;  1P3R A;  1WJM A;  1LB1 A;  2UZS A;  1WG7 A;  3PEG A;  3SYX A;  3D8E A;  1N3H A;  5J3T A;  4HAZ B;  4HB4 B;  1ZVR A;  1ZSQ A;  1RRP B;  5C79 A;  2RNR B;  5HE2 A;  4HHV A;  5LON B;  5KCV A;  4GN1 A;  2UZR A;  1H10 A;  3CXB B;  2H7E A;  1UNR A;  4F7G A;  4DX8 A;  4A6K A;  2HTH B;  2AL6 A;  3N7C A;  1U5G A;  2DHI A;  2KGX B;  1P6S A;  4GPT B;  1W1G A;  1W1H A;  2N0Y A;  3T06 A;  5HE0 A;  1GG3 A;  5DIF B;  4KVG B;  3AJ4 A;  1V5M A;  5DH9 B;  2BCJ A;  2LOX A;  2M14 A;  4GXB A;  4C0A A;  1Y19 B;  2DKQ A;  3FM8 C;  4CYE A;  1BWN A;  2LKO A;  1PLS A;  5DHA B;  1ISN A;  2K2J A;  1V5U A;  1EGX A;  4EJN A;  2DFK A;  1XCG A;  4EMO A;  1FHW A;  1UNQ A;  5HE3 A;  2EMT A;  2CY5 A;  3QWM A;  1M7E A;  2ELB A;  5KQ1 A;  1W1D A;  1QC6 A;  2W2W A;  1I7A A;  1DDW A;  4CHM A;  1K5D B;  3KY9 A;  4MY6 A;  1FOE A;  1AWE A;  2DA0 A;  3TW1 A;  3ODO A;  4DX9 0;  2ADZ A;  1PMS A;  1U27 A;  1Y5O A;  2XQN M;  1GC7 A;  2MKR A;  2LYD A;  1SHC A;  2Y8F A;  2DYQ A;  5GOW B;  1Q67 A;  3O96 A;  2K2U A;  3G9W A;  2D9V A;  5D3X A;  3ULC A;  3PSC A;  2HE7 A;  1TXD A;  3M1I B;  2DLW A;  4A5K A;  1KZ7 A;  3SUZ A;  3KRX A;  2KUP A;  2GCJ A;  2ROZ B;  4DBB A;  3FSS A;  3F0W A;  5LOP B;  3PP2 A;  2CY4 A;  1UPQ A;  3WYF B;  5C5B A;  3PZD A;  2FJL A;  3MDB C;  4HB2 B;  3MPX A;  1UEF A;  2RGN B;  1MAI A;  1U5E A;  4HAV B;  4IOY X;  2I1J A;  1TJ6 A;  1V5P A;  4HB0 B;  1NU2 A;  2YS5 A;  2L2I A;  2VSZ A;  2EC1 A;  1NI2 A;  1XD4 A;  2LUL A;  4WVF B;  1KZG A;  2MWN B;  2R09 A;  4NSW A;  1U5F A;  1TQZ A;  2RVB B;  1QQG A;  4WJ7 A;  1X11 A;  3TFM A;  1FAO A;  1X05 A;  1MIZ B;  4HDO A;  2COF A;  1MK7 B;  5D3Y A;  4PQ0 A;  1MPH A;  3ML4 A;  2E2X A;  4IAP A;  2Q13 A;  3FEH A;  3PVU A;  4A6F B;  4HAT B;  2DN6 A;  1I2H A;  5C16 A;  4P7I A;  3BIN A;  2N23 A;  3IVF A;  4MT7 A;  2GJY A;  1MKE A;  2R0D A;  1ZC3 B;  2DX1 A;  2X18 A;  1KI1 B;  3A98 B;  5CLL B;  4ZRK A;  2P0D A;  3ODX A;  4F7H A;  5CLQ B;  1OQN A;  4KHB B;  1J19 A;  2DKP A;  2P8V A;  4K2O A;  5FI0 A;  2KCJ A;  2NMB A;  2D10 A;  2EJ8 A;  1SGH A;  4K2P A;  3TCA A;  1OMW A;  1U2B A;  4A6F A;  1RJ2 A;  2RUK B;  4HAU B;  1BAK A;  2Y8G A;  3HW2 B;  1EVH A;  4HDQ A;  1FHX A;  2J0J A;  4Z2M B;  4CHJ A;  3PVW A;  4EKU A;  4GMX B;  1BTN A;  2P0H A;  2DTC A;  1WGQ A;  3F5R A;  2MFQ A;  1V61 A;  3X23 A;  4HAY B;  2M38 A;  3ZDT A;  2Z0Q A;  2IYB A;  2J0M A;  3PVL A;  3HK0 A;  2D9Y A;  2H7D A;  2D11 A;  3KZ1 A;  5D27 A;  4TYZ A;  2QKM A;  2CRF A;  2I1K A;  2D9W A;  2YT0 A;  2COA A;  3AU4 A;  1DYN A;  2Z0P A;  2OQB A;  2MDX A;  4HB3 B;  1V88 A;  1XX0 A;  1PFJ A;  3RCP A;  2YSZ A;  1M7R A;  1E5W A;  4Z2N A;  1U5D A;  1WVH A;  1NTV A;  1Z87 A;  1X1G A;  1MIX A;  2OTX A;  2NZ8 B;  5L81 A;  4K81 A;  3QBV B;  3WA0 A;  2LG1 A;  2Y7B A;  4D0N B;  2QKL A;  3ZVR A;  1NTY A;  2EMS A;  3D8F A;  2PZ1 A;  3PG7 A;  4BBK A;  1DDM A;  4ZRJ A;  1UPR A;  2K00 A;  2V76 A;  1J0W A;  2COC A;  4YL8 A;  3D8D A;  3GYP A;  1XKE A;  4TKN A;  1K5G B;  3TO1 A;  2YVC A;  3GYO A;  1EAZ A;  4HAX B;  3U7D A;  4MK0 A;  5J3Y A;  2DX5 A;  3DXC A;  2L1C A;  1P5T A;  4XWX A;  4YON A;  3KRW A;  5DI9 B;  2IFS A;  2W2X C;  1FB8 A;  1ZM0 A;  2YF0 A;  4HAW B;  2ELA A;  2UVM A;  4A6H A;  2I5C A;  2YS3 A;  1OY2 A;  4GMV A;  1DDV A;  4KHO A;  1FGZ A;  4B6H A;  3DXD A;  4Y94 A;  3BJI A;  1B55 A;  1MK9 B;  1V89 A;  3TVV A;  3V5W A;  3A8P A;  5JHG A;  1FGY A;  3OAN A;  2YS1 A;  3SO6 A;  5HE1 A;  2VKI A;  4DXA B;  2CAY A;  2LOZ A;  2G35 A;  1WGU A;  2DHK A;  1XR0 B;  2D9Z A;  2RLO A;  3P6A A;  2GCL A;  3LJU X;  5JHH A;  2ZPY A;  2DHJ A;  3AU5 A;  2D4Q A;  2P0F A;  2JP2 A;  1ZC4 B;  3A8Q A;  3SNH A;  3HQC A;  5FI1 A;  3KSY A;  1FHO A;  1GC6 A;  2GS0 A;  5J3Q A;  1BTK A;  5C5B B;  1UNP A;  3VOQ A;  1WI1 A;  1LW3 A;  5JLJ B;  5D3W A;  1DRO A;  4GZU A;  1X1F A;  2ROV A;  3U8Z A;  3ULB A;  4K17 A;  1U29 A;  3ODW A;  4NY0 A;  4WSF A;  3QIJ A;  5JP4 A;  2W2X D;  2J59 M;  4H8S A;  5C6R A;  1X86 A;  3SV1 A;  1WJ1 A;  2YT1 A;  4PNK A;  3NSU A;  2Z0O A;  2D2Q A;  3DXE A;  4F7U P;  3CIK A;  5DHF B;  5KQ4 A;  2I5F A;  2YRY A;  2DYN A;  1DBH A;  4KAX B;  1XOD A;  3P7Z A;  5EFX A;  2COD A;  1IRS A;  1H4R A;  2RSG A;  4L6E A;  4IFS A;  3UZT A;  2D9X A;  4ZRI A;  1EF1 A;  1AQC A; 
#chains in the Genus database with same CATH topology
 2J0K A;  4D6W A;  3VIA A;  4KHA A;  5D3V A;  3HIE A;  2AEH A;  2VRW B;  1P3R A;  1WJM A;  1LB1 A;  2UZS A;  1WG7 A;  3PEG A;  2Z14 A;  3SYX A;  3D8E A;  1N3H A;  5J3T A;  4HAZ B;  4HB4 B;  1ZVR A;  2Z59 A;  1ZSQ A;  1RRP B;  3U12 A;  5C79 A;  2RNR B;  5HE2 A;  5M4Y B;  4HHV A;  5LON B;  5KCV A;  4GN1 A;  2UZR A;  1H10 A;  3CXB B;  2H7E A;  1UNR A;  4F7G A;  4DX8 A;  4A6K A;  2HTH B;  2AL6 A;  3N7C A;  1U5G A;  2K49 A;  2DHI A;  2KGX B;  3NW8 A;  1P6S A;  4GPT B;  1W1G A;  1W1H A;  2N0Y A;  3T06 A;  5HE0 A;  1GG3 A;  5DIF B;  4KVG B;  3AJ4 A;  1V5M A;  5DH9 B;  2BCJ A;  2LOX A;  5LG4 B;  2M14 A;  4GXB A;  4C0A A;  1Y19 B;  2DKQ A;  3FM8 C;  4CYE A;  1BWN A;  2LKO A;  1PLS A;  5DHA B;  1ISN A;  2K2J A;  1V5U A;  5I2M A;  4EJN A;  2DFK A;  1EGX A;  1XCG A;  4EMO A;  1FHW A;  5I2S A;  1UNQ A;  5HE3 A;  2EMT A;  2CY5 A;  3QWM A;  1M7E A;  2ELB A;  5KQ1 A;  1W1D A;  1QC6 A;  2W2W A;  1I7A A;  1DDW A;  4CHM A;  1K5D B;  3A58 A;  3KY9 A;  4MY6 A;  1FOE A;  1AWE A;  2DA0 A;  3TW1 A;  3OHM B;  3NWD A;  3ODO A;  4DX9 0;  2ADZ A;  1PMS A;  1U27 A;  1Y5O A;  2XQN M;  2Z4D A;  1GC7 A;  2MKR A;  2LYD A;  1SHC A;  2Y8F A;  2DYQ A;  5GOW B;  1Q67 A;  3O96 A;  4OSN A;  3G9W A;  2K2U A;  2D9V A;  5D3X A;  3ULC A;  3PSC A;  2HE7 A;  1TXD A;  3M1I B;  2DLW A;  4A5K A;  1KZ7 A;  3SUZ A;  3KRX A;  2KUP A;  2GCJ A;  2ROZ B;  4DBB A;  3FSS A;  5IRS A;  1ZYI A;  3F0W A;  5LOP B;  3PP2 A;  2CY4 A;  1UPQ A;  3WYF B;  5C5B A;  3PZD A;  2FJL A;  3MDB C;  4HB2 B;  3MPX A;  1UEF A;  2RGN B;  1MAI A;  1U5E A;  4HAV B;  4IOY X;  2I1J A;  1TJ6 A;  1V5P A;  4HB0 B;  1NU2 A;  2YS5 A;  2L2I A;  2VSZ A;  2EC1 A;  2YT2 A;  1NI2 A;  1XD4 A;  4QJ5 B;  2LUL A;  4WVF B;  1KZG A;  2MWN B;  2R09 A;  4NSW A;  1U5F A;  1TQZ A;  2RVB B;  1QQG A;  4WJ7 A;  1X11 A;  3TFM A;  1FAO A;  1X05 A;  1MIZ B;  4HDO A;  2COF A;  1MK7 B;  5D3Y A;  4PQ0 A;  1MPH A;  3ML4 A;  2E2X A;  4IAP A;  2Q13 A;  3FEH A;  3PVU A;  4A6F B;  3NWA A;  4HAT B;  2DN6 A;  1I2H A;  5C16 A;  4P7I A;  4QXA B;  3BIN A;  2N23 A;  3IVF A;  4MT7 A;  2GJY A;  1MKE A;  2R0D A;  1ZC3 B;  3B77 A;  2DX1 A;  2X18 A;  1KI1 B;  3A98 B;  5CLL B;  4ZRK A;  2P0D A;  3ODX A;  4F7H A;  5CLQ B;  1OQN A;  4DIX A;  2FJU B;  2KIE A;  4KHB B;  1J19 A;  2DKP A;  2P8V A;  4K2O A;  5FI0 A;  2KCJ A;  2NMB A;  4QJ4 B;  2D10 A;  2EJ8 A;  1SGH A;  4K2P A;  3TCA A;  1OMW A;  1U2B A;  2Z13 A;  4A6F A;  1RJ2 A;  2RUK B;  4HAU B;  1BAK A;  2Y8G A;  4L1R A;  3HW2 B;  1EVH A;  4HDQ A;  1FHX A;  2J0J A;  4Z2M B;  4CHJ A;  3PVW A;  4EKU A;  4GMX B;  1BTN A;  2P0H A;  2DTC A;  3HSA A;  1WGQ A;  3F5R A;  3NWF A;  2MFQ A;  1V61 A;  3X23 A;  4HAY B;  2M38 A;  4KHB A;  4OT1 A;  3ZDT A;  2Z0Q A;  2IYB A;  4CSQ A;  2J0M A;  3PVL A;  3HK0 A;  2D9Y A;  2H7D A;  2D11 A;  3KZ1 A;  5D27 A;  4TYZ A;  2QKM A;  2CRF A;  2KIG A;  2I1K A;  2D9W A;  2GUM A;  2YT0 A;  2COA A;  3AU4 A;  1DYN A;  2Z0P A;  2OQB A;  2MDX A;  4HB3 B;  1V88 A;  1XX0 A;  1PFJ A;  3RCP A;  4GNK B;  2YSZ A;  1M7R A;  1E5W A;  4Z2N A;  1U5D A;  1WVH A;  1NTV A;  1Z87 A;  2K8E A;  1X1G A;  1MIX A;  2OTX A;  2NZ8 B;  5L81 A;  4K81 A;  3QBV B;  3WA0 A;  2LG1 A;  2Y7B A;  4D0N B;  2QKL A;  3ZVR A;  1NTY A;  2EMS A;  3D8F A;  2PZ1 A;  3PG7 A;  4BBK A;  1DDM A;  4ZRJ A;  1UPR A;  2K00 A;  2V76 A;  1J0W A;  2COC A;  4YL8 A;  3D8D A;  3GYP A;  1XKE A;  4TKN A;  1K5G B;  3TO1 A;  2ZKM X;  2YVC A;  3GYO A;  1EAZ A;  4HAX B;  3U7D A;  4MK0 A;  5J3Y A;  2DX5 A;  2KUQ A;  3DXC A;  2L1C A;  1P5T A;  3FVC A;  4XWX A;  4YON A;  3KRW A;  2NBV A;  5DI9 B;  2IFS A;  2W2X C;  1FB8 A;  1ZM0 A;  2YF0 A;  4HAW B;  2ELA A;  2UVM A;  4A6H A;  2I5C A;  2YS3 A;  1OY2 A;  4GMV A;  1DDV A;  4KHO A;  1MI1 A;  1FGZ A;  4B6H A;  3DXD A;  4Y94 A;  3BJI A;  1B55 A;  1MK9 B;  1V89 A;  3TVV A;  3V5W A;  3A8P A;  5JHG A;  1FGY A;  3OAN A;  2YS1 A;  4HSI A;  3SO6 A;  5HE1 A;  2VKI A;  4DXA B;  2CAY A;  2LOZ A;  2G35 A;  1WGU A;  2DHK A;  1XR0 B;  2D9Z A;  2RLO A;  3P6A A;  2GCL A;  3LJU X;  5JHH A;  2ZPY A;  2DHJ A;  3AU5 A;  2KR0 A;  2D4Q A;  2P0F A;  2JP2 A;  1ZC4 B;  3A8Q A;  3SNH A;  3HQC A;  5FI1 A;  3KSY A;  1FHO A;  1GC6 A;  2GS0 A;  5J3Q A;  1BTK A;  4GOU A;  5C5B B;  1UNP A;  3VOQ A;  1WI1 A;  1LW3 A;  5JLJ B;  5D3W A;  1DRO A;  4GZU A;  1X1F A;  2ROV A;  3U8Z A;  3ULB A;  3DCX A;  4K17 A;  1U29 A;  3ODW A;  4NY0 A;  4WSF A;  3QIJ A;  5JP4 A;  2W2X D;  2J59 M;  4H8S A;  5C6R A;  1T77 A;  1X86 A;  3SV1 A;  1WJ1 A;  2YT1 A;  2RRF A;  4PNK A;  3NSU A;  2Z0O A;  2D2Q A;  3DXE A;  4F7U P;  3CIK A;  5DHF B;  5KQ4 A;  2I5F A;  2YRY A;  2DYN A;  1DBH A;  4QJ3 B;  4KAX B;  1XOD A;  3P7Z A;  5EFX A;  2COD A;  1IRS A;  2R2Y A;  1H4R A;  2RSG A;  4L6E A;  4IFS A;  3UZT A;  2D9X A;  4ZRI A;  1EF1 A;  1AQC A; 
#chains in the Genus database with same CATH homology
 2J0K A;  3VIA A;  4KHA A;  5D3V A;  2AEH A;  2VRW B;  1P3R A;  1WJM A;  1LB1 A;  2UZS A;  1WG7 A;  3PEG A;  3SYX A;  3D8E A;  1N3H A;  5J3T A;  4HAZ B;  4HB4 B;  1ZVR A;  1ZSQ A;  1RRP B;  5C79 A;  2RNR B;  5HE2 A;  4HHV A;  5LON B;  5KCV A;  4GN1 A;  2UZR A;  1H10 A;  3CXB B;  2H7E A;  1UNR A;  4F7G A;  4DX8 A;  4A6K A;  2HTH B;  2AL6 A;  3N7C A;  1U5G A;  2DHI A;  2KGX B;  1P6S A;  4GPT B;  1W1G A;  1W1H A;  2N0Y A;  3T06 A;  5HE0 A;  1GG3 A;  5DIF B;  4KVG B;  3AJ4 A;  1V5M A;  5DH9 B;  2BCJ A;  2LOX A;  2M14 A;  4GXB A;  4C0A A;  1Y19 B;  2DKQ A;  3FM8 C;  4CYE A;  1BWN A;  2LKO A;  1PLS A;  5DHA B;  1ISN A;  2K2J A;  1V5U A;  1EGX A;  4EJN A;  2DFK A;  1XCG A;  4EMO A;  1FHW A;  1UNQ A;  5HE3 A;  2EMT A;  2CY5 A;  3QWM A;  1M7E A;  2ELB A;  5KQ1 A;  1W1D A;  1QC6 A;  2W2W A;  1I7A A;  1DDW A;  4CHM A;  1K5D B;  3KY9 A;  4MY6 A;  1FOE A;  1AWE A;  2DA0 A;  3TW1 A;  3ODO A;  4DX9 0;  2ADZ A;  1PMS A;  1U27 A;  1Y5O A;  2XQN M;  1GC7 A;  2MKR A;  2LYD A;  1SHC A;  2Y8F A;  2DYQ A;  5GOW B;  1Q67 A;  3O96 A;  2K2U A;  3G9W A;  2D9V A;  5D3X A;  3ULC A;  3PSC A;  2HE7 A;  1TXD A;  3M1I B;  2DLW A;  4A5K A;  1KZ7 A;  3SUZ A;  3KRX A;  2KUP A;  2GCJ A;  2ROZ B;  4DBB A;  3FSS A;  3F0W A;  5LOP B;  3PP2 A;  2CY4 A;  1UPQ A;  3WYF B;  5C5B A;  3PZD A;  2FJL A;  3MDB C;  4HB2 B;  3MPX A;  1UEF A;  2RGN B;  1MAI A;  1U5E A;  4HAV B;  4IOY X;  2I1J A;  1TJ6 A;  1V5P A;  4HB0 B;  1NU2 A;  2YS5 A;  2L2I A;  2VSZ A;  2EC1 A;  1NI2 A;  1XD4 A;  2LUL A;  4WVF B;  1KZG A;  2MWN B;  2R09 A;  4NSW A;  1U5F A;  1TQZ A;  2RVB B;  1QQG A;  4WJ7 A;  1X11 A;  3TFM A;  1FAO A;  1X05 A;  1MIZ B;  4HDO A;  2COF A;  1MK7 B;  5D3Y A;  4PQ0 A;  1MPH A;  3ML4 A;  2E2X A;  4IAP A;  2Q13 A;  3FEH A;  3PVU A;  4A6F B;  4HAT B;  2DN6 A;  1I2H A;  5C16 A;  4P7I A;  3BIN A;  2N23 A;  3IVF A;  4MT7 A;  2GJY A;  1MKE A;  2R0D A;  1ZC3 B;  2DX1 A;  2X18 A;  1KI1 B;  3A98 B;  5CLL B;  4ZRK A;  2P0D A;  3ODX A;  4F7H A;  5CLQ B;  1OQN A;  4KHB B;  1J19 A;  2DKP A;  2P8V A;  4K2O A;  5FI0 A;  2KCJ A;  2NMB A;  2D10 A;  2EJ8 A;  1SGH A;  4K2P A;  3TCA A;  1OMW A;  1U2B A;  4A6F A;  1RJ2 A;  2RUK B;  4HAU B;  1BAK A;  2Y8G A;  3HW2 B;  1EVH A;  4HDQ A;  1FHX A;  2J0J A;  4Z2M B;  4CHJ A;  3PVW A;  4EKU A;  4GMX B;  1BTN A;  2P0H A;  2DTC A;  1WGQ A;  3F5R A;  2MFQ A;  1V61 A;  3X23 A;  4HAY B;  2M38 A;  3ZDT A;  2Z0Q A;  2IYB A;  2J0M A;  3PVL A;  3HK0 A;  2D9Y A;  2H7D A;  2D11 A;  3KZ1 A;  5D27 A;  4TYZ A;  2QKM A;  2CRF A;  2I1K A;  2D9W A;  2YT0 A;  2COA A;  3AU4 A;  1DYN A;  2Z0P A;  2OQB A;  2MDX A;  4HB3 B;  1V88 A;  1XX0 A;  1PFJ A;  3RCP A;  2YSZ A;  1M7R A;  1E5W A;  4Z2N A;  1U5D A;  1WVH A;  1NTV A;  1Z87 A;  1X1G A;  1MIX A;  2OTX A;  2NZ8 B;  5L81 A;  4K81 A;  3QBV B;  3WA0 A;  2LG1 A;  2Y7B A;  4D0N B;  2QKL A;  3ZVR A;  1NTY A;  2EMS A;  3D8F A;  2PZ1 A;  3PG7 A;  4BBK A;  1DDM A;  4ZRJ A;  1UPR A;  2K00 A;  2V76 A;  1J0W A;  2COC A;  4YL8 A;  3D8D A;  3GYP A;  1XKE A;  4TKN A;  1K5G B;  3TO1 A;  2YVC A;  3GYO A;  1EAZ A;  4HAX B;  3U7D A;  4MK0 A;  5J3Y A;  2DX5 A;  3DXC A;  2L1C A;  1P5T A;  4XWX A;  4YON A;  3KRW A;  5DI9 B;  2IFS A;  2W2X C;  1FB8 A;  1ZM0 A;  2YF0 A;  4HAW B;  2ELA A;  2UVM A;  4A6H A;  2I5C A;  2YS3 A;  1OY2 A;  4GMV A;  1DDV A;  4KHO A;  1FGZ A;  4B6H A;  3DXD A;  4Y94 A;  3BJI A;  1B55 A;  1MK9 B;  1V89 A;  3TVV A;  3V5W A;  3A8P A;  5JHG A;  1FGY A;  3OAN A;  2YS1 A;  3SO6 A;  5HE1 A;  2VKI A;  4DXA B;  2CAY A;  2LOZ A;  2G35 A;  1WGU A;  2DHK A;  1XR0 B;  2D9Z A;  2RLO A;  3P6A A;  2GCL A;  3LJU X;  5JHH A;  2ZPY A;  2DHJ A;  3AU5 A;  2D4Q A;  2P0F A;  2JP2 A;  1ZC4 B;  3A8Q A;  3SNH A;  3HQC A;  5FI1 A;  3KSY A;  1FHO A;  1GC6 A;  2GS0 A;  5J3Q A;  1BTK A;  5C5B B;  1UNP A;  3VOQ A;  1WI1 A;  1LW3 A;  5JLJ B;  5D3W A;  1DRO A;  4GZU A;  1X1F A;  2ROV A;  3U8Z A;  3ULB A;  4K17 A;  1U29 A;  3ODW A;  4NY0 A;  4WSF A;  3QIJ A;  5JP4 A;  2W2X D;  2J59 M;  4H8S A;  5C6R A;  1X86 A;  3SV1 A;  1WJ1 A;  2YT1 A;  4PNK A;  3NSU A;  2Z0O A;  2D2Q A;  3DXE A;  4F7U P;  3CIK A;  5DHF B;  5KQ4 A;  2I5F A;  2YRY A;  2DYN A;  1DBH A;  4KAX B;  1XOD A;  3P7Z A;  5EFX A;  2COD A;  1IRS A;  1H4R A;  2RSG A;  4L6E A;  4IFS A;  3UZT A;  2D9X A;  4ZRI A;  1EF1 A;  1AQC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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