5D3WA

Crystal structure of the p-rex1 ph domain with sulfate bound
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
total genus 45
structure length 151
sequence length 166
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3wA00
1SGHA 2H7DA 2D9YA 2H7EA 4DXAB 2AL6A 4YL8A 4HDQA 1UEFA 3VOQA 2DHIA 2CY5A 1ISNA 3KRXA 2LG1A 2D9ZA 2J59M 3FSSA 2EMSA 2RLOA 4HAUB 2M38A 2DA0A 3HQCA 5DH9B 3CXBB 1MPHA 3KZ1A 3M1IB 3ODWA 1XR0B 3PG7A 3SV1A 4A6FB 2J0KA 2R09A 3MPXA 3TCAA 1M7RA 3VIAA 1ZC4B 2PZ1A 2YRYA 4CYEA 1V5MA 2KCJA 4PNKA 2DTCA 2MWNB 3O96A 1Y19B 2X18A 2L2IA 1MKEA 5C5BB 4WVFB 1MK7B 2RSGA 3UZTA 1BWNA 3PVWA 4IOYX 3KY9A 2UVMA 3ULBA 4HHVA 1FHXA 1UPRA 4F7GA 2RUKB 2GCLA 3A98B 2IYBA 1KZ7A 3ULCA 1OY2A 5KCVA 1H4RA 3F0WA 2YS1A 1MIZB 1N3HA 3SYXA 4EJNA 2K2JA 2G35A 1EGXA 4HB4B 5C16A 5HE2A 1ZSQA 1OQNA 2D2QA 3G9WA 2YS5A 4MK0A 3RCPA 1WJ1A 5LONB 3P6AA 4HDOA 2K2UA 2M14A 1UNPA 3U7DA 1FHWA 2NZ8B 1WG7A 2QKLA 1U2BA 4BBKA 3DXEA 3FM8C 4K17A 3IVFA 2DX5A 3N7CA 2Y8GA 2YT1A 3ML4A 4DBBA 3A8QA 1WGQA 2COCA 2DHKA 2ROZB 5KQ1A 2DYNA 2LOXA 1EVHA 1P6SA 1TJ6A 5C5BA 1W1HA 3GYOA 1U5GA 3ZDTA 2W2XD 4KVGB 2CY4A 1FB8A 2P0DA 3PSCA 2Y7BA 5EFXA 1Q67A 1SHCA 3A8PA 2J0MA 3T06A 1DROA 3PEGA 2R0DA 4CHMA 5HE0A 1DBHA 4D0NB 3GYPA 1U5DA 1Z87A 3QBVB 5FI0A 5KQ4A 3LJUX 4H8SA 4XWXA 2YF0A 1QC6A 4NY0A 1AWEA 4HAVB 4DX8A 3V5WA 2BCJA 2L1CA 2JP2A 1P5TA 2AEHA 3FEHA 1V89A 3WYFB 1DDMA 3DXDA 3X23A 4HAYB 2MFQA 4C0AA 2P8VA 4TKNA 5J3QA 1UNQA 1EAZA 2RGNB 3PVLA 1AQCA 2VSZA 2ELBA 1V5UA 2KUPA 3PVUA 2D11A 2D4QA 1UNRA 3NSUA 1DYNA 1RJ2A 4TYZA 2DHJA 2LOZA 1XCGA 1B55A 1GC6A 4Z2MB 3ODOA 1K5GB 3TO1A 4EKUA 3AJ4A 1E5WA 1NTYA 2W2WA 2DFKA 2DYQA 1UPQA 1TQZA 2I1JA 1J0WA 2DLWA 1V61A 2CAYA 1V5PA 4WSFA 4HATB 2Z0PA 4EMOA 5JHGA 2Y8FA 2DKPA 4Z2NA 4Y94A 5FI1A 3DXCA 1TXDA 3QWMA 4A6FA 1FOEA 1NTVA 2RVBB 1U5EA 2VRWB 1X05A 2Z0QA 1WJMA 4ZRIA 2I5CA 2EMTA 5D3WA 2EC1A 4MT7A 3P7ZA 1FHOA 1DDVA 1I7AA 2VKIA 1U5FA 2DX1A 2D10A 1LB1A 4PQ0A 2NMBA 4K2PA 5DHAB 2MKRA 2RNRB 5D3VA 1ZC3B 1BAKA 3ODXA 1XD4A 1DDWA 1MAIA 5JP4A 4KHOA 5L81A 4GN1A 4HB0B 2ZPYA 2ROVA 3SUZA 1XODA 5J3TA 4GPTB 1MK9B 1ZVRA 2MDXA 5LOPB 4YONA 4F7UP 1U29A 3PZDA 1V88A 2P0HA 3TVVA 2YVCA 4KHBB 2YT0A 2GCJA 1U27A 1BTNA 5GOWB 1IRSA 1BTKA 2KGXB 3D8DA 1H10A 2HTHB 1Y5OA 2OQBA 2N23A 2YS3A 2FJLA 1GC7A 2J0JA 2GS0A 5D27A 1GG3A 3KSYA 4DX90 1QQGA 4NSWA 2UZSA 4F7HA 1FAOA 1PFJA 2P0FA 1K5DB 3MDBC 3PP2A 4IAPA 4HAZB 1M7EA 1X86A 2I1KA 1W1GA 4P7IA 2DKQA 1XKEA 2YSZA 1W1DA 2GJYA 2ELAA 4KHAA 3SNHA 2HE7A 4GMVA 2N0YA 1NU2A 3TFMA 3OANA 4WJ7A 2LYDA 5DIFB 1P3RA 2COFA 5D3YA 1WVHA 1WI1A 3U8ZA 2Z0OA 2QKMA 4K2OA 2CODA 2D9VA 3D8EA 1MIXA 3HK0A 5CLQB 3KRWA 4HB2B 2V76A 1FGYA 2OTXA 3D8FA 3F5RA 4L6EA 3TW1A 2ADZA 2UZRA 3AU5A 4KAXB 1KZGA 5JHHA 5DHFB 1XX0A 2I5FA 3AU4A 5D3XA 1X1GA 2DN6A 4ZRJA 2LULA 2IFSA 1PMSA 4A6KA 2Q13A 5C79A 2D9WA 3HW2B 5J3YA 2D9XA 1RRPB 3QIJA 4CHJA 5JLJB 4K81A 3CIKA 1X1FA 2XQNM 1OMWA 2COAA 2EJ8A 5C6RA 5HE1A 1WGUA 2CRFA 1NI2A 1KI1B 2LKOA 3BINA 4GZUA 1ZM0A 1EF1A 3BJIA 1FGZA 1X11A 5DI9B 4IFSA 4HB3B 3SO6A 1I2HA 1J19A 4B6HA 4GXBA 4ZRKA 2E2XA 2W2XC 4A5KA 4A6HA 3WA0A 4HAWB 5HE3A 1LW3A 4MY6A 5CLLB 4HAXB 4GMXB 2K00A 3ZVRA 1PLSA
chains in the Genus database with same CATH superfamily
1SGHA 2H7DA 2D9YA 2H7EA 4DXAB 4GOUA 2AL6A 4YL8A 4HDQA 1UEFA 3VOQA 2DHIA 2CY5A 1ISNA 3KRXA 3U12A 2LG1A 2D9ZA 2J59M 3FSSA 2EMSA 2RLOA 4GNKB 4HAUB 2M38A 2DA0A 5M4YB 3HQCA 5DH9B 3CXBB 1MPHA 3KZ1A 3M1IB 3ODWA 1XR0B 3PG7A 3SV1A 4A6FB 2J0KA 2R09A 3MPXA 3TCAA 1M7RA 3VIAA 1ZC4B 2PZ1A 2Z14A 2YRYA 4CYEA 1V5MA 2KCJA 4PNKA 2DTCA 2MWNB 3O96A 1Y19B 2X18A 2L2IA 1MKEA 5C5BB 4WVFB 1MK7B 2RSGA 3UZTA 2KIGA 1BWNA 3PVWA 4IOYX 5IRSA 3KY9A 2UVMA 3ULBA 4HHVA 1FHXA 1UPRA 4F7GA 2RUKB 2RRFA 2GCLA 3A98B 2IYBA 2KUQA 1KZ7A 3ULCA 1OY2A 5KCVA 1H4RA 3F0WA 2YS1A 1MIZB 1N3HA 3SYXA 4EJNA 2K2JA 2G35A 1EGXA 4HB4B 3NWAA 5C16A 5HE2A 1ZSQA 1OQNA 2D2QA 1MI1A 3G9WA 2YS5A 4MK0A 1ZYIA 3RCPA 1WJ1A 5LONB 3P6AA 4HDOA 2K2UA 1T77A 2M14A 2Z59A 1UNPA 3U7DA 1FHWA 2NZ8B 1WG7A 2QKLA 1U2BA 4BBKA 3DXEA 3FM8C 4K17A 3IVFA 2DX5A 3N7CA 2Y8GA 2YT1A 3ML4A 4DBBA 3A8QA 1WGQA 2COCA 2DHKA 2ROZB 5KQ1A 2DYNA 2LOXA 1EVHA 1P6SA 1TJ6A 5C5BA 1W1HA 3GYOA 1U5GA 3ZDTA 2W2XD 4KVGB 2CY4A 1FB8A 3NWDA 2P0DA 3PSCA 2Y7BA 3FVCA 2NBVA 5EFXA 1Q67A 1SHCA 3A8PA 2J0MA 3T06A 1DROA 4DIXA 5LG4B 3PEGA 2R0DA 4CHMA 5HE0A 1DBHA 4D0NB 3GYPA 1U5DA 1Z87A 3QBVB 5FI0A 5KQ4A 3LJUX 4H8SA 4XWXA 2YF0A 1QC6A 4NY0A 1AWEA 4HAVB 4DX8A 3V5WA 2BCJA 3A58A 4QJ5B 2L1CA 2JP2A 1P5TA 2AEHA 3FEHA 1V89A 3WYFB 2Z13A 1DDMA 3DXDA 3X23A 4HAYB 2MFQA 4C0AA 4OSNA 2P8VA 4TKNA 4HSIA 5J3QA 1UNQA 1EAZA 2RGNB 3PVLA 1AQCA 2VSZA 2ELBA 1V5UA 2KUPA 3NW8A 3PVUA 2KR0A 2D11A 2D4QA 1UNRA 3NSUA 1DYNA 1RJ2A 4TYZA 2DHJA 2YT2A 2LOZA 1XCGA 1B55A 1GC6A 4Z2MB 3ODOA 1K5GB 3TO1A 4EKUA 3AJ4A 1E5WA 1NTYA 2W2WA 2DFKA 2DYQA 1UPQA 2FJUB 1TQZA 2I1JA 1J0WA 2ZKMX 2DLWA 1V61A 2CAYA 1V5PA 4WSFA 4HATB 2Z0PA 4EMOA 5JHGA 2Y8FA 2DKPA 4Z2NA 4Y94A 5FI1A 3DXCA 1TXDA 3QWMA 4A6FA 1FOEA 1NTVA 2RVBB 4OT1A 1U5EA 2VRWB 1X05A 2Z0QA 1WJMA 4ZRIA 2I5CA 2EMTA 5D3WA 2EC1A 4MT7A 3P7ZA 1FHOA 1DDVA 1I7AA 2VKIA 1U5FA 2DX1A 2D10A 1LB1A 4PQ0A 4D6WA 2NMBA 4K2PA 5DHAB 2MKRA 2RNRB 5D3VA 1ZC3B 1BAKA 4CSQA 5I2SA 3ODXA 1XD4A 1DDWA 1MAIA 5JP4A 2K8EA 4KHOA 5L81A 4GN1A 4HB0B 2ZPYA 2ROVA 3SUZA 1XODA 5J3TA 4GPTB 1MK9B 1ZVRA 2MDXA 5LOPB 4QXAB 4YONA 4F7UP 1U29A 3PZDA 1V88A 2P0HA 3TVVA 2YVCA 4KHBB 2YT0A 2GCJA 1U27A 1BTNA 5GOWB 1IRSA 1BTKA 2KGXB 3D8DA 1H10A 2HTHB 1Y5OA 2R2YA 2OQBA 2N23A 2YS3A 2FJLA 1GC7A 2J0JA 2GS0A 5D27A 1GG3A 3KSYA 4DX90 1QQGA 4NSWA 2UZSA 4F7HA 1FAOA 1PFJA 3OHMB 2P0FA 1K5DB 3MDBC 3PP2A 4IAPA 4HAZB 1M7EA 1X86A 3HIEA 1W1GA 2I1KA 2DKQA 4P7IA 1XKEA 2GUMA 2YSZA 1W1DA 2GJYA 2ELAA 4KHAA 3SNHA 2HE7A 4GMVA 2N0YA 2Z4DA 1NU2A 3TFMA 3OANA 4WJ7A 2LYDA 5DIFB 1P3RA 2COFA 5D3YA 1WVHA 1WI1A 3U8ZA 2Z0OA 2QKMA 4K2OA 2CODA 2D9VA 3D8EA 1MIXA 3HK0A 5CLQB 3KRWA 4HB2B 2V76A 1FGYA 3DCXA 2OTXA 3B77A 3D8FA 4L1RA 3NWFA 3F5RA 4L6EA 3TW1A 4QJ3B 2ADZA 2UZRA 3AU5A 4KAXB 1KZGA 5JHHA 4QJ4B 5DHFB 1XX0A 2I5FA 3AU4A 5D3XA 1X1GA 2DN6A 4ZRJA 2LULA 2IFSA 1PMSA 4KHBA 4A6KA 2Q13A 5C79A 2D9WA 3HW2B 5J3YA 2D9XA 1RRPB 3QIJA 4CHJA 5JLJB 4K81A 3CIKA 1X1FA 2XQNM 1OMWA 2COAA 2EJ8A 5C6RA 3HSAA 5HE1A 1WGUA 2CRFA 1NI2A 1KI1B 2LKOA 3BINA 4GZUA 1ZM0A 1EF1A 3BJIA 5I2MA 1FGZA 1X11A 5DI9B 4IFSA 2KIEA 4HB3B 3SO6A 1I2HA 1J19A 4B6HA 4GXBA 4ZRKA 2E2XA 2W2XC 4A5KA 4A6HA 3WA0A 4HAWB 5HE3A 1LW3A 4MY6A 5CLLB 4HAXB 4GMXB 2K00A 3ZVRA 2K49A 1PLSA
chains in the Genus database with same CATH topology
1SGHA 2H7DA 2D9YA 2H7EA 4DXAB 2AL6A 4YL8A 4HDQA 1UEFA 3VOQA 2DHIA 2CY5A 1ISNA 3KRXA 2LG1A 2D9ZA 2J59M 3FSSA 2EMSA 2RLOA 4HAUB 2M38A 2DA0A 3HQCA 5DH9B 3CXBB 1MPHA 3KZ1A 3M1IB 3ODWA 1XR0B 3PG7A 3SV1A 4A6FB 2J0KA 2R09A 3MPXA 3TCAA 1M7RA 3VIAA 1ZC4B 2PZ1A 2YRYA 4CYEA 1V5MA 2KCJA 4PNKA 2DTCA 2MWNB 3O96A 1Y19B 2X18A 2L2IA 1MKEA 5C5BB 4WVFB 1MK7B 2RSGA 3UZTA 1BWNA 3PVWA 4IOYX 3KY9A 2UVMA 3ULBA 4HHVA 1FHXA 1UPRA 4F7GA 2RUKB 2GCLA 3A98B 2IYBA 1KZ7A 3ULCA 1OY2A 5KCVA 1H4RA 3F0WA 2YS1A 1MIZB 1N3HA 3SYXA 4EJNA 2K2JA 2G35A 1EGXA 4HB4B 5C16A 5HE2A 1ZSQA 1OQNA 2D2QA 3G9WA 2YS5A 4MK0A 3RCPA 1WJ1A 5LONB 3P6AA 4HDOA 2K2UA 2M14A 1UNPA 3U7DA 1FHWA 2NZ8B 1WG7A 2QKLA 1U2BA 4BBKA 3DXEA 3FM8C 4K17A 3IVFA 2DX5A 3N7CA 2Y8GA 2YT1A 3ML4A 4DBBA 3A8QA 1WGQA 2COCA 2DHKA 2ROZB 5KQ1A 2DYNA 2LOXA 1EVHA 1P6SA 1TJ6A 5C5BA 1W1HA 3GYOA 1U5GA 3ZDTA 2W2XD 4KVGB 2CY4A 1FB8A 2P0DA 3PSCA 2Y7BA 5EFXA 1Q67A 1SHCA 3A8PA 2J0MA 3T06A 1DROA 3PEGA 2R0DA 4CHMA 5HE0A 1DBHA 4D0NB 3GYPA 1U5DA 1Z87A 3QBVB 5FI0A 5KQ4A 3LJUX 4H8SA 4XWXA 2YF0A 1QC6A 4NY0A 1AWEA 4HAVB 4DX8A 3V5WA 2BCJA 2L1CA 2JP2A 1P5TA 2AEHA 3FEHA 1V89A 3WYFB 1DDMA 3DXDA 3X23A 4HAYB 2MFQA 4C0AA 2P8VA 4TKNA 5J3QA 1UNQA 1EAZA 2RGNB 3PVLA 1AQCA 2VSZA 2ELBA 1V5UA 2KUPA 3PVUA 2D11A 2D4QA 1UNRA 3NSUA 1DYNA 1RJ2A 4TYZA 2DHJA 2LOZA 1XCGA 1B55A 1GC6A 4Z2MB 3ODOA 1K5GB 3TO1A 4EKUA 3AJ4A 1E5WA 1NTYA 2W2WA 2DFKA 2DYQA 1UPQA 1TQZA 2I1JA 1J0WA 2DLWA 1V61A 2CAYA 1V5PA 4WSFA 4HATB 2Z0PA 4EMOA 5JHGA 2Y8FA 2DKPA 4Z2NA 4Y94A 5FI1A 3DXCA 1TXDA 3QWMA 4A6FA 1FOEA 1NTVA 2RVBB 1U5EA 2VRWB 1X05A 2Z0QA 1WJMA 4ZRIA 2I5CA 2EMTA 5D3WA 2EC1A 4MT7A 3P7ZA 1FHOA 1DDVA 1I7AA 2VKIA 1U5FA 2DX1A 2D10A 1LB1A 4PQ0A 2NMBA 4K2PA 5DHAB 2MKRA 2RNRB 5D3VA 1ZC3B 1BAKA 3ODXA 1XD4A 1DDWA 1MAIA 5JP4A 4KHOA 5L81A 4GN1A 4HB0B 2ZPYA 2ROVA 3SUZA 1XODA 5J3TA 4GPTB 1MK9B 1ZVRA 2MDXA 5LOPB 4YONA 4F7UP 1U29A 3PZDA 1V88A 2P0HA 3TVVA 2YVCA 4KHBB 2YT0A 2GCJA 1U27A 1BTNA 5GOWB 1IRSA 1BTKA 2KGXB 3D8DA 1H10A 2HTHB 1Y5OA 2OQBA 2N23A 2YS3A 2FJLA 1GC7A 2J0JA 2GS0A 5D27A 1GG3A 3KSYA 4DX90 1QQGA 4NSWA 2UZSA 4F7HA 1FAOA 1PFJA 2P0FA 1K5DB 3MDBC 3PP2A 4IAPA 4HAZB 1M7EA 1X86A 2I1KA 1W1GA 4P7IA 2DKQA 1XKEA 2YSZA 1W1DA 2GJYA 2ELAA 4KHAA 3SNHA 2HE7A 4GMVA 2N0YA 1NU2A 3TFMA 3OANA 4WJ7A 2LYDA 5DIFB 1P3RA 2COFA 5D3YA 1WVHA 1WI1A 3U8ZA 2Z0OA 2QKMA 4K2OA 2CODA 2D9VA 3D8EA 1MIXA 3HK0A 5CLQB 3KRWA 4HB2B 2V76A 1FGYA 2OTXA 3D8FA 3F5RA 4L6EA 3TW1A 2ADZA 2UZRA 3AU5A 4KAXB 1KZGA 5JHHA 5DHFB 1XX0A 2I5FA 3AU4A 5D3XA 1X1GA 2DN6A 4ZRJA 2LULA 2IFSA 1PMSA 4A6KA 2Q13A 5C79A 2D9WA 3HW2B 5J3YA 2D9XA 1RRPB 3QIJA 4CHJA 5JLJB 4K81A 3CIKA 1X1FA 2XQNM 1OMWA 2COAA 2EJ8A 5C6RA 5HE1A 1WGUA 2CRFA 1NI2A 1KI1B 2LKOA 3BINA 4GZUA 1ZM0A 1EF1A 3BJIA 1FGZA 1X11A 5DI9B 4IFSA 4HB3B 3SO6A 1I2HA 1J19A 4B6HA 4GXBA 4ZRKA 2E2XA 2W2XC 4A5KA 4A6HA 3WA0A 4HAWB 5HE3A 1LW3A 4MY6A 5CLLB 4HAXB 4GMXB 2K00A 3ZVRA 1PLSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SGH A;  2H7D A;  2D9Y A;  2H7E A;  4DXA B;  2AL6 A;  4YL8 A;  4HDQ A;  1UEF A;  3VOQ A;  2DHI A;  2CY5 A;  1ISN A;  3KRX A;  2LG1 A;  2D9Z A;  2J59 M;  3FSS A;  2EMS A;  2RLO A;  4HAU B;  2M38 A;  2DA0 A;  3HQC A;  5DH9 B;  3CXB B;  1MPH A;  3KZ1 A;  3M1I B;  3ODW A;  1XR0 B;  3PG7 A;  3SV1 A;  4A6F B;  2J0K A;  2R09 A;  3MPX A;  3TCA A;  1M7R A;  3VIA A;  1ZC4 B;  2PZ1 A;  2YRY A;  4CYE A;  1V5M A;  2KCJ A;  4PNK A;  2DTC A;  2MWN B;  3O96 A;  1Y19 B;  2X18 A;  2L2I A;  1MKE A;  5C5B B;  4WVF B;  1MK7 B;  2RSG A;  3UZT A;  1BWN A;  3PVW A;  4IOY X;  3KY9 A;  2UVM A;  3ULB A;  4HHV A;  1FHX A;  1UPR A;  4F7G A;  2RUK B;  2GCL A;  3A98 B;  2IYB A;  1KZ7 A;  3ULC A;  1OY2 A;  5KCV A;  1H4R A;  3F0W A;  2YS1 A;  1MIZ B;  1N3H A;  3SYX A;  4EJN A;  2K2J A;  2G35 A;  1EGX A;  4HB4 B;  5C16 A;  5HE2 A;  1ZSQ A;  1OQN A;  2D2Q A;  3G9W A;  2YS5 A;  4MK0 A;  3RCP A;  1WJ1 A;  5LON B;  3P6A A;  4HDO A;  2K2U A;  2M14 A;  1UNP A;  3U7D A;  1FHW A;  2NZ8 B;  1WG7 A;  2QKL A;  1U2B A;  4BBK A;  3DXE A;  3FM8 C;  4K17 A;  3IVF A;  2DX5 A;  3N7C A;  2Y8G A;  2YT1 A;  3ML4 A;  4DBB A;  3A8Q A;  1WGQ A;  2COC A;  2DHK A;  2ROZ B;  5KQ1 A;  2DYN A;  2LOX A;  1EVH A;  1P6S A;  1TJ6 A;  5C5B A;  1W1H A;  3GYO A;  1U5G A;  3ZDT A;  2W2X D;  4KVG B;  2CY4 A;  1FB8 A;  2P0D A;  3PSC A;  2Y7B A;  5EFX A;  1Q67 A;  1SHC A;  3A8P A;  2J0M A;  3T06 A;  1DRO A;  3PEG A;  2R0D A;  4CHM A;  5HE0 A;  1DBH A;  4D0N B;  3GYP A;  1U5D A;  1Z87 A;  3QBV B;  5FI0 A;  5KQ4 A;  3LJU X;  4H8S A;  4XWX A;  2YF0 A;  1QC6 A;  4NY0 A;  1AWE A;  4HAV B;  4DX8 A;  3V5W A;  2BCJ A;  2L1C A;  2JP2 A;  1P5T A;  2AEH A;  3FEH A;  1V89 A;  3WYF B;  1DDM A;  3DXD A;  3X23 A;  4HAY B;  2MFQ A;  4C0A A;  2P8V A;  4TKN A;  5J3Q A;  1UNQ A;  1EAZ A;  2RGN B;  3PVL A;  1AQC A;  2VSZ A;  2ELB A;  1V5U A;  2KUP A;  3PVU A;  2D11 A;  2D4Q A;  1UNR A;  3NSU A;  1DYN A;  1RJ2 A;  4TYZ A;  2DHJ A;  2LOZ A;  1XCG A;  1B55 A;  1GC6 A;  4Z2M B;  3ODO A;  1K5G B;  3TO1 A;  4EKU A;  3AJ4 A;  1E5W A;  1NTY A;  2W2W A;  2DFK A;  2DYQ A;  1UPQ A;  1TQZ A;  2I1J A;  1J0W A;  2DLW A;  1V61 A;  2CAY A;  1V5P A;  4WSF A;  4HAT B;  2Z0P A;  4EMO A;  5JHG A;  2Y8F A;  2DKP A;  4Z2N A;  4Y94 A;  5FI1 A;  3DXC A;  1TXD A;  3QWM A;  4A6F A;  1FOE A;  1NTV A;  2RVB B;  1U5E A;  2VRW B;  1X05 A;  2Z0Q A;  1WJM A;  4ZRI A;  2I5C A;  2EMT A;  5D3W A;  2EC1 A;  4MT7 A;  3P7Z A;  1FHO A;  1DDV A;  1I7A A;  2VKI A;  1U5F A;  2DX1 A;  2D10 A;  1LB1 A;  4PQ0 A;  2NMB A;  4K2P A;  5DHA B;  2MKR A;  2RNR B;  5D3V A;  1ZC3 B;  1BAK A;  3ODX A;  1XD4 A;  1DDW A;  1MAI A;  5JP4 A;  4KHO A;  5L81 A;  4GN1 A;  4HB0 B;  2ZPY A;  2ROV A;  3SUZ A;  1XOD A;  5J3T A;  4GPT B;  1MK9 B;  1ZVR A;  2MDX A;  5LOP B;  4YON A;  4F7U P;  1U29 A;  3PZD A;  1V88 A;  2P0H A;  3TVV A;  2YVC A;  4KHB B;  2YT0 A;  2GCJ A;  1U27 A;  1BTN A;  5GOW B;  1IRS A;  1BTK A;  2KGX B;  3D8D A;  1H10 A;  2HTH B;  1Y5O A;  2OQB A;  2N23 A;  2YS3 A;  2FJL A;  1GC7 A;  2J0J A;  2GS0 A;  5D27 A;  1GG3 A;  3KSY A;  4DX9 0;  1QQG A;  4NSW A;  2UZS A;  4F7H A;  1FAO A;  1PFJ A;  2P0F A;  1K5D B;  3MDB C;  3PP2 A;  4IAP A;  4HAZ B;  1M7E A;  1X86 A;  2I1K A;  1W1G A;  4P7I A;  2DKQ A;  1XKE A;  2YSZ A;  1W1D A;  2GJY A;  2ELA A;  4KHA A;  3SNH A;  2HE7 A;  4GMV A;  2N0Y A;  1NU2 A;  3TFM A;  3OAN A;  4WJ7 A;  2LYD A;  5DIF B;  1P3R A;  2COF A;  5D3Y A;  1WVH A;  1WI1 A;  3U8Z A;  2Z0O A;  2QKM A;  4K2O A;  2COD A;  2D9V A;  3D8E A;  1MIX A;  3HK0 A;  5CLQ B;  3KRW A;  4HB2 B;  2V76 A;  1FGY A;  2OTX A;  3D8F A;  3F5R A;  4L6E A;  3TW1 A;  2ADZ A;  2UZR A;  3AU5 A;  4KAX B;  1KZG A;  5JHH A;  5DHF B;  1XX0 A;  2I5F A;  3AU4 A;  5D3X A;  1X1G A;  2DN6 A;  4ZRJ A;  2LUL A;  2IFS A;  1PMS A;  4A6K A;  2Q13 A;  5C79 A;  2D9W A;  3HW2 B;  5J3Y A;  2D9X A;  1RRP B;  3QIJ A;  4CHJ A;  5JLJ B;  4K81 A;  3CIK A;  1X1F A;  2XQN M;  1OMW A;  2COA A;  2EJ8 A;  5C6R A;  5HE1 A;  1WGU A;  2CRF A;  1NI2 A;  1KI1 B;  2LKO A;  3BIN A;  4GZU A;  1ZM0 A;  1EF1 A;  3BJI A;  1FGZ A;  1X11 A;  5DI9 B;  4IFS A;  4HB3 B;  3SO6 A;  1I2H A;  1J19 A;  4B6H A;  4GXB A;  4ZRK A;  2E2X A;  2W2X C;  4A5K A;  4A6H A;  3WA0 A;  4HAW B;  5HE3 A;  1LW3 A;  4MY6 A;  5CLL B;  4HAX B;  4GMX B;  2K00 A;  3ZVR A;  1PLS A; 
#chains in the Genus database with same CATH topology
 1SGH A;  2H7D A;  2D9Y A;  2H7E A;  4DXA B;  4GOU A;  2AL6 A;  4YL8 A;  4HDQ A;  1UEF A;  3VOQ A;  2DHI A;  2CY5 A;  1ISN A;  3KRX A;  3U12 A;  2LG1 A;  2D9Z A;  2J59 M;  3FSS A;  2EMS A;  2RLO A;  4GNK B;  4HAU B;  2M38 A;  2DA0 A;  5M4Y B;  3HQC A;  5DH9 B;  3CXB B;  1MPH A;  3KZ1 A;  3M1I B;  3ODW A;  1XR0 B;  3PG7 A;  3SV1 A;  4A6F B;  2J0K A;  2R09 A;  3MPX A;  3TCA A;  1M7R A;  3VIA A;  1ZC4 B;  2PZ1 A;  2Z14 A;  2YRY A;  4CYE A;  1V5M A;  2KCJ A;  4PNK A;  2DTC A;  2MWN B;  3O96 A;  1Y19 B;  2X18 A;  2L2I A;  1MKE A;  5C5B B;  4WVF B;  1MK7 B;  2RSG A;  3UZT A;  2KIG A;  1BWN A;  3PVW A;  4IOY X;  5IRS A;  3KY9 A;  2UVM A;  3ULB A;  4HHV A;  1FHX A;  1UPR A;  4F7G A;  2RUK B;  2RRF A;  2GCL A;  3A98 B;  2IYB A;  2KUQ A;  1KZ7 A;  3ULC A;  1OY2 A;  5KCV A;  1H4R A;  3F0W A;  2YS1 A;  1MIZ B;  1N3H A;  3SYX A;  4EJN A;  2K2J A;  2G35 A;  1EGX A;  4HB4 B;  3NWA A;  5C16 A;  5HE2 A;  1ZSQ A;  1OQN A;  2D2Q A;  1MI1 A;  3G9W A;  2YS5 A;  4MK0 A;  1ZYI A;  3RCP A;  1WJ1 A;  5LON B;  3P6A A;  4HDO A;  2K2U A;  1T77 A;  2M14 A;  2Z59 A;  1UNP A;  3U7D A;  1FHW A;  2NZ8 B;  1WG7 A;  2QKL A;  1U2B A;  4BBK A;  3DXE A;  3FM8 C;  4K17 A;  3IVF A;  2DX5 A;  3N7C A;  2Y8G A;  2YT1 A;  3ML4 A;  4DBB A;  3A8Q A;  1WGQ A;  2COC A;  2DHK A;  2ROZ B;  5KQ1 A;  2DYN A;  2LOX A;  1EVH A;  1P6S A;  1TJ6 A;  5C5B A;  1W1H A;  3GYO A;  1U5G A;  3ZDT A;  2W2X D;  4KVG B;  2CY4 A;  1FB8 A;  3NWD A;  2P0D A;  3PSC A;  2Y7B A;  3FVC A;  2NBV A;  5EFX A;  1Q67 A;  1SHC A;  3A8P A;  2J0M A;  3T06 A;  1DRO A;  4DIX A;  5LG4 B;  3PEG A;  2R0D A;  4CHM A;  5HE0 A;  1DBH A;  4D0N B;  3GYP A;  1U5D A;  1Z87 A;  3QBV B;  5FI0 A;  5KQ4 A;  3LJU X;  4H8S A;  4XWX A;  2YF0 A;  1QC6 A;  4NY0 A;  1AWE A;  4HAV B;  4DX8 A;  3V5W A;  2BCJ A;  3A58 A;  4QJ5 B;  2L1C A;  2JP2 A;  1P5T A;  2AEH A;  3FEH A;  1V89 A;  3WYF B;  2Z13 A;  1DDM A;  3DXD A;  3X23 A;  4HAY B;  2MFQ A;  4C0A A;  4OSN A;  2P8V A;  4TKN A;  4HSI A;  5J3Q A;  1UNQ A;  1EAZ A;  2RGN B;  3PVL A;  1AQC A;  2VSZ A;  2ELB A;  1V5U A;  2KUP A;  3NW8 A;  3PVU A;  2KR0 A;  2D11 A;  2D4Q A;  1UNR A;  3NSU A;  1DYN A;  1RJ2 A;  4TYZ A;  2DHJ A;  2YT2 A;  2LOZ A;  1XCG A;  1B55 A;  1GC6 A;  4Z2M B;  3ODO A;  1K5G B;  3TO1 A;  4EKU A;  3AJ4 A;  1E5W A;  1NTY A;  2W2W A;  2DFK A;  2DYQ A;  1UPQ A;  2FJU B;  1TQZ A;  2I1J A;  1J0W A;  2ZKM X;  2DLW A;  1V61 A;  2CAY A;  1V5P A;  4WSF A;  4HAT B;  2Z0P A;  4EMO A;  5JHG A;  2Y8F A;  2DKP A;  4Z2N A;  4Y94 A;  5FI1 A;  3DXC A;  1TXD A;  3QWM A;  4A6F A;  1FOE A;  1NTV A;  2RVB B;  4OT1 A;  1U5E A;  2VRW B;  1X05 A;  2Z0Q A;  1WJM A;  4ZRI A;  2I5C A;  2EMT A;  5D3W A;  2EC1 A;  4MT7 A;  3P7Z A;  1FHO A;  1DDV A;  1I7A A;  2VKI A;  1U5F A;  2DX1 A;  2D10 A;  1LB1 A;  4PQ0 A;  4D6W A;  2NMB A;  4K2P A;  5DHA B;  2MKR A;  2RNR B;  5D3V A;  1ZC3 B;  1BAK A;  4CSQ A;  5I2S A;  3ODX A;  1XD4 A;  1DDW A;  1MAI A;  5JP4 A;  2K8E A;  4KHO A;  5L81 A;  4GN1 A;  4HB0 B;  2ZPY A;  2ROV A;  3SUZ A;  1XOD A;  5J3T A;  4GPT B;  1MK9 B;  1ZVR A;  2MDX A;  5LOP B;  4QXA B;  4YON A;  4F7U P;  1U29 A;  3PZD A;  1V88 A;  2P0H A;  3TVV A;  2YVC A;  4KHB B;  2YT0 A;  2GCJ A;  1U27 A;  1BTN A;  5GOW B;  1IRS A;  1BTK A;  2KGX B;  3D8D A;  1H10 A;  2HTH B;  1Y5O A;  2R2Y A;  2OQB A;  2N23 A;  2YS3 A;  2FJL A;  1GC7 A;  2J0J A;  2GS0 A;  5D27 A;  1GG3 A;  3KSY A;  4DX9 0;  1QQG A;  4NSW A;  2UZS A;  4F7H A;  1FAO A;  1PFJ A;  3OHM B;  2P0F A;  1K5D B;  3MDB C;  3PP2 A;  4IAP A;  4HAZ B;  1M7E A;  1X86 A;  3HIE A;  1W1G A;  2I1K A;  2DKQ A;  4P7I A;  1XKE A;  2GUM A;  2YSZ A;  1W1D A;  2GJY A;  2ELA A;  4KHA A;  3SNH A;  2HE7 A;  4GMV A;  2N0Y A;  2Z4D A;  1NU2 A;  3TFM A;  3OAN A;  4WJ7 A;  2LYD A;  5DIF B;  1P3R A;  2COF A;  5D3Y A;  1WVH A;  1WI1 A;  3U8Z A;  2Z0O A;  2QKM A;  4K2O A;  2COD A;  2D9V A;  3D8E A;  1MIX A;  3HK0 A;  5CLQ B;  3KRW A;  4HB2 B;  2V76 A;  1FGY A;  3DCX A;  2OTX A;  3B77 A;  3D8F A;  4L1R A;  3NWF A;  3F5R A;  4L6E A;  3TW1 A;  4QJ3 B;  2ADZ A;  2UZR A;  3AU5 A;  4KAX B;  1KZG A;  5JHH A;  4QJ4 B;  5DHF B;  1XX0 A;  2I5F A;  3AU4 A;  5D3X A;  1X1G A;  2DN6 A;  4ZRJ A;  2LUL A;  2IFS A;  1PMS A;  4KHB A;  4A6K A;  2Q13 A;  5C79 A;  2D9W A;  3HW2 B;  5J3Y A;  2D9X A;  1RRP B;  3QIJ A;  4CHJ A;  5JLJ B;  4K81 A;  3CIK A;  1X1F A;  2XQN M;  1OMW A;  2COA A;  2EJ8 A;  5C6R A;  3HSA A;  5HE1 A;  1WGU A;  2CRF A;  1NI2 A;  1KI1 B;  2LKO A;  3BIN A;  4GZU A;  1ZM0 A;  1EF1 A;  3BJI A;  5I2M A;  1FGZ A;  1X11 A;  5DI9 B;  4IFS A;  2KIE A;  4HB3 B;  3SO6 A;  1I2H A;  1J19 A;  4B6H A;  4GXB A;  4ZRK A;  2E2X A;  2W2X C;  4A5K A;  4A6H A;  3WA0 A;  4HAW B;  5HE3 A;  1LW3 A;  4MY6 A;  5CLL B;  4HAX B;  4GMX B;  2K00 A;  3ZVR A;  2K49 A;  1PLS A; 
#chains in the Genus database with same CATH homology
 1SGH A;  2H7D A;  2D9Y A;  2H7E A;  4DXA B;  2AL6 A;  4YL8 A;  4HDQ A;  1UEF A;  3VOQ A;  2DHI A;  2CY5 A;  1ISN A;  3KRX A;  2LG1 A;  2D9Z A;  2J59 M;  3FSS A;  2EMS A;  2RLO A;  4HAU B;  2M38 A;  2DA0 A;  3HQC A;  5DH9 B;  3CXB B;  1MPH A;  3KZ1 A;  3M1I B;  3ODW A;  1XR0 B;  3PG7 A;  3SV1 A;  4A6F B;  2J0K A;  2R09 A;  3MPX A;  3TCA A;  1M7R A;  3VIA A;  1ZC4 B;  2PZ1 A;  2YRY A;  4CYE A;  1V5M A;  2KCJ A;  4PNK A;  2DTC A;  2MWN B;  3O96 A;  1Y19 B;  2X18 A;  2L2I A;  1MKE A;  5C5B B;  4WVF B;  1MK7 B;  2RSG A;  3UZT A;  1BWN A;  3PVW A;  4IOY X;  3KY9 A;  2UVM A;  3ULB A;  4HHV A;  1FHX A;  1UPR A;  4F7G A;  2RUK B;  2GCL A;  3A98 B;  2IYB A;  1KZ7 A;  3ULC A;  1OY2 A;  5KCV A;  1H4R A;  3F0W A;  2YS1 A;  1MIZ B;  1N3H A;  3SYX A;  4EJN A;  2K2J A;  2G35 A;  1EGX A;  4HB4 B;  5C16 A;  5HE2 A;  1ZSQ A;  1OQN A;  2D2Q A;  3G9W A;  2YS5 A;  4MK0 A;  3RCP A;  1WJ1 A;  5LON B;  3P6A A;  4HDO A;  2K2U A;  2M14 A;  1UNP A;  3U7D A;  1FHW A;  2NZ8 B;  1WG7 A;  2QKL A;  1U2B A;  4BBK A;  3DXE A;  3FM8 C;  4K17 A;  3IVF A;  2DX5 A;  3N7C A;  2Y8G A;  2YT1 A;  3ML4 A;  4DBB A;  3A8Q A;  1WGQ A;  2COC A;  2DHK A;  2ROZ B;  5KQ1 A;  2DYN A;  2LOX A;  1EVH A;  1P6S A;  1TJ6 A;  5C5B A;  1W1H A;  3GYO A;  1U5G A;  3ZDT A;  2W2X D;  4KVG B;  2CY4 A;  1FB8 A;  2P0D A;  3PSC A;  2Y7B A;  5EFX A;  1Q67 A;  1SHC A;  3A8P A;  2J0M A;  3T06 A;  1DRO A;  3PEG A;  2R0D A;  4CHM A;  5HE0 A;  1DBH A;  4D0N B;  3GYP A;  1U5D A;  1Z87 A;  3QBV B;  5FI0 A;  5KQ4 A;  3LJU X;  4H8S A;  4XWX A;  2YF0 A;  1QC6 A;  4NY0 A;  1AWE A;  4HAV B;  4DX8 A;  3V5W A;  2BCJ A;  2L1C A;  2JP2 A;  1P5T A;  2AEH A;  3FEH A;  1V89 A;  3WYF B;  1DDM A;  3DXD A;  3X23 A;  4HAY B;  2MFQ A;  4C0A A;  2P8V A;  4TKN A;  5J3Q A;  1UNQ A;  1EAZ A;  2RGN B;  3PVL A;  1AQC A;  2VSZ A;  2ELB A;  1V5U A;  2KUP A;  3PVU A;  2D11 A;  2D4Q A;  1UNR A;  3NSU A;  1DYN A;  1RJ2 A;  4TYZ A;  2DHJ A;  2LOZ A;  1XCG A;  1B55 A;  1GC6 A;  4Z2M B;  3ODO A;  1K5G B;  3TO1 A;  4EKU A;  3AJ4 A;  1E5W A;  1NTY A;  2W2W A;  2DFK A;  2DYQ A;  1UPQ A;  1TQZ A;  2I1J A;  1J0W A;  2DLW A;  1V61 A;  2CAY A;  1V5P A;  4WSF A;  4HAT B;  2Z0P A;  4EMO A;  5JHG A;  2Y8F A;  2DKP A;  4Z2N A;  4Y94 A;  5FI1 A;  3DXC A;  1TXD A;  3QWM A;  4A6F A;  1FOE A;  1NTV A;  2RVB B;  1U5E A;  2VRW B;  1X05 A;  2Z0Q A;  1WJM A;  4ZRI A;  2I5C A;  2EMT A;  5D3W A;  2EC1 A;  4MT7 A;  3P7Z A;  1FHO A;  1DDV A;  1I7A A;  2VKI A;  1U5F A;  2DX1 A;  2D10 A;  1LB1 A;  4PQ0 A;  2NMB A;  4K2P A;  5DHA B;  2MKR A;  2RNR B;  5D3V A;  1ZC3 B;  1BAK A;  3ODX A;  1XD4 A;  1DDW A;  1MAI A;  5JP4 A;  4KHO A;  5L81 A;  4GN1 A;  4HB0 B;  2ZPY A;  2ROV A;  3SUZ A;  1XOD A;  5J3T A;  4GPT B;  1MK9 B;  1ZVR A;  2MDX A;  5LOP B;  4YON A;  4F7U P;  1U29 A;  3PZD A;  1V88 A;  2P0H A;  3TVV A;  2YVC A;  4KHB B;  2YT0 A;  2GCJ A;  1U27 A;  1BTN A;  5GOW B;  1IRS A;  1BTK A;  2KGX B;  3D8D A;  1H10 A;  2HTH B;  1Y5O A;  2OQB A;  2N23 A;  2YS3 A;  2FJL A;  1GC7 A;  2J0J A;  2GS0 A;  5D27 A;  1GG3 A;  3KSY A;  4DX9 0;  1QQG A;  4NSW A;  2UZS A;  4F7H A;  1FAO A;  1PFJ A;  2P0F A;  1K5D B;  3MDB C;  3PP2 A;  4IAP A;  4HAZ B;  1M7E A;  1X86 A;  2I1K A;  1W1G A;  4P7I A;  2DKQ A;  1XKE A;  2YSZ A;  1W1D A;  2GJY A;  2ELA A;  4KHA A;  3SNH A;  2HE7 A;  4GMV A;  2N0Y A;  1NU2 A;  3TFM A;  3OAN A;  4WJ7 A;  2LYD A;  5DIF B;  1P3R A;  2COF A;  5D3Y A;  1WVH A;  1WI1 A;  3U8Z A;  2Z0O A;  2QKM A;  4K2O A;  2COD A;  2D9V A;  3D8E A;  1MIX A;  3HK0 A;  5CLQ B;  3KRW A;  4HB2 B;  2V76 A;  1FGY A;  2OTX A;  3D8F A;  3F5R A;  4L6E A;  3TW1 A;  2ADZ A;  2UZR A;  3AU5 A;  4KAX B;  1KZG A;  5JHH A;  5DHF B;  1XX0 A;  2I5F A;  3AU4 A;  5D3X A;  1X1G A;  2DN6 A;  4ZRJ A;  2LUL A;  2IFS A;  1PMS A;  4A6K A;  2Q13 A;  5C79 A;  2D9W A;  3HW2 B;  5J3Y A;  2D9X A;  1RRP B;  3QIJ A;  4CHJ A;  5JLJ B;  4K81 A;  3CIK A;  1X1F A;  2XQN M;  1OMW A;  2COA A;  2EJ8 A;  5C6R A;  5HE1 A;  1WGU A;  2CRF A;  1NI2 A;  1KI1 B;  2LKO A;  3BIN A;  4GZU A;  1ZM0 A;  1EF1 A;  3BJI A;  1FGZ A;  1X11 A;  5DI9 B;  4IFS A;  4HB3 B;  3SO6 A;  1I2H A;  1J19 A;  4B6H A;  4GXB A;  4ZRK A;  2E2X A;  2W2X C;  4A5K A;  4A6H A;  3WA0 A;  4HAW B;  5HE3 A;  1LW3 A;  4MY6 A;  5CLL B;  4HAX B;  4GMX B;  2K00 A;  3ZVR A;  1PLS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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