5D3WA

Crystal structure of the p-rex1 ph domain with sulfate bound
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
166
structure length
151
Chain Sequence
GEFEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVYCKRKINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGWKIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Lipid binding protein
molecule keywords Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac excha
total genus 45
structure length 151
sequence length 166
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-08-06
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.29.30 Mainly Beta Roll PH-domain like Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 5d3wA00
2EMSA 3MPXA 2Y8FA 3A8PA 2P0HA 5D3YA 1BTNA 1Z87A 1XR0B 1TQZA 2KGXB 2K00A 2Y7BA 2DYQA 1FHXA 2QKMA 2DX1A 5C5BB 1UNRA 1XODA 2AL6A 2CODA 2ADZA 3BINA 4CYEA 3HK0A 4IAPA 5HE3A 1V5PA 3TCAA 3VOQA 1XD4A 5DIFB 2K2UA 3QWMA 3PSCA 1FGYA 3WA0A 3F0WA 2DHJA 5L81A 2Z0QA 1X05A 1MK9B 1J0WA 1ZVRA 2Z0OA 3FEHA 3O96A 2CRFA 1DDVA 1U5FA 1TXDA 1X1FA 1PMSA 1V89A 2D9XA 4HB0B 2LULA 1WJ1A 2UZSA 2VKIA 2W2XC 1X1GA 4MT7A 2DA0A 3A8QA 1OMWA 3BJIA 2PZ1A 2RVBB 2YS3A 4C0AA 5KCVA 2OQBA 2RUKB 1GC6A 2YT1A 2HE7A 3KZ1A 4YONA 1ZC3B 3PP2A 1SGHA 2I5CA 5HE0A 2RNRB 4NSWA 5JHHA 4K2PA 4K81A 2GCLA 3AU5A 3X23A 2LKOA 2D9VA 1V88A 4IOYX 1XCGA 4HAZB 1U2BA 1NI2A 3TO1A 4KVGB 4ZRJA 2I5FA 1ZSQA 1ISNA 4MK0A 5GOWB 2DYNA 5FI0A 4TKNA 2X18A 5LONB 4HAWB 2K2JA 5C6RA 1BTKA 3ODWA 1PLSA 3AU4A 1MK7B 2L2IA 3ULCA 3A98B 3OANA 4K17A 3DXCA 4KHAA 3RCPA 5D27A 1X11A 4L6EA 1GG3A 5HE1A 1FOEA 1U27A 1NU2A 4GXBA 4MY6A 4DX8A 5C5BA 5FI1A 2COAA 4HAXB 1B55A 1P3RA 3MDBC 4WJ7A 3D8EA 2EMTA 2M14A 2MDXA 2VSZA 4DX90 1NTYA 1UEFA 2YVCA 2YS1A 2XQNM 1RJ2A 5J3TA 3VIAA 1P6SA 5D3XA 1M7EA 2UVMA 1BAKA 3KY9A 2ELBA 5C16A 4HB4B 3F5RA 4B6HA 1DYNA 4HDOA 5HE2A 1LB1A 4HATB 3FSSA 4XWXA 1UNQA 3FM8C 3SV1A 1ZC4B 2CY4A 2M38A 1N3HA 3AJ4A 4BBKA 3SYXA 4HDQA 4K2OA 1U5GA 1KZGA 1KZ7A 1W1GA 4YL8A 4GMXB 2RLOA 1X86A 2D9YA 3ZDTA 1WJMA 3T06A 2MFQA 1EF1A 1FB8A 2H7DA 1MPHA 1P5TA 5DH9B 2P0DA 1V5UA 4GMVA 1U5DA 4A6HA 2DX5A 5JP4A 1E5WA 1SHCA 4D0NB 3DXDA 2I1JA 2Z0PA 1V5MA 4KHOA 2D9WA 3G9WA 1K5DB 1UPQA 4PQ0A 2R0DA 2IYBA 4A6FA 1J19A 1U5EA 3QBVB 2EC1A 4HAYB 1RRPB 4EKUA 3ODXA 3PVWA 3TVVA 2DKPA 2Y8GA 1WVHA 2YSZA 2G35A 2J0JA 2RGNB 3ML4A 3DXEA 4F7HA 2YF0A 2VRWB 2EJ8A 2GS0A 2ROZB 4Z2MB 3ODOA 1FAOA 2W2WA 3U8ZA 1IRSA 2N23A 5CLLB 2COCA 2Q13A 1AWEA 4CHMA 2W2XD 1UNPA 2NZ8B 3P6AA 3WYFB 2ELAA 4GN1A 2DHKA 4A5KA 2LOXA 4WSFA 5EFXA 2DFKA 1KI1B 5DI9B 4A6FB 5LOPB 4EJNA 2ROVA 1H10A 1U29A 2KUPA 4Z2NA 2RSGA 5C79A 3TFMA 1ZM0A 2I1KA 1MIZB 2R09A 4Y94A 3PZDA 5KQ4A 4HAVB 4EMOA 2J0MA 2UZRA 3ULBA 1Q67A 1AQCA 1Y19B 4GZUA 3CXBB 2HTHB 4KHBB 1H4RA 1WGUA 2DN6A 1DBHA 1NTVA 3PG7A 4F7UP 3SNHA 2D11A 3D8FA 2IFSA 4DBBA 5D3VA 2N0YA 1Y5OA 2P0FA 2DHIA 1UPRA 5J3QA 4NY0A 2DKQA 4A6KA 2CAYA 1MAIA 1QQGA 2J0KA 1EAZA 1FGZA 4F7GA 3UZTA 4P7IA 3D8DA 2GJYA 3KSYA 5D3WA 1OQNA 2MKRA 2E2XA 5JHGA 1EVHA 2D2QA 1W1HA 3PEGA 1OY2A 1BWNA 1WI1A 2D9ZA 2P8VA 2V76A 4HB2B 4HHVA 4ZRIA 1FHOA 3IVFA 2JP2A 4GPTB 2LYDA 2DTCA 4CHJA 3HQCA 1I7AA 1M7RA 1PFJA 3N7CA 1W1DA 2J59M 1TJ6A 3KRXA 3PVUA 5DHAB 2YS5A 1MIXA 1MKEA 4HB3B 2L1CA 2FJLA 3P7ZA 1V61A 5J3YA 2D4QA 2KCJA 3V5WA 3GYPA 1WG7A 3GYOA 2QKLA 2COFA 3LJUX 2AEHA 4KAXB 2CY5A 1XX0A 1GC7A 1DDWA 2ZPYA 2LG1A 5CLQB 3M1IB 4WVFB 4PNKA 4HAUB 1FHWA 1I2HA 3SUZA 1DROA 3NSUA 2NMBA 5JLJB 2OTXA 3HW2B 3U7DA 3PVLA 3ZVRA 2H7EA 2MWNB 1K5GB 3CIKA 4H8SA 2BCJA 4DXAB 5DHFB 4ZRKA 2D10A 1QC6A 3KRWA 3SO6A 1DDMA 1LW3A 1WGQA 3QIJA 2YRYA 2LOZA 1XKEA 3TW1A 2DLWA 4IFSA 4TYZA 5KQ1A 1EGXA 2YT0A 2GCJA
chains in the Genus database with same CATH superfamily
2EMSA 3MPXA 2Y8FA 3A8PA 4QXAB 2Z14A 2P0HA 5D3YA 1BTNA 1Z87A 1XR0B 1TQZA 2KGXB 2K00A 2Y7BA 2DYQA 1FHXA 2QKMA 2DX1A 5C5BB 1UNRA 2KUQA 1XODA 2AL6A 2CODA 2ADZA 3BINA 4CYEA 3HK0A 4IAPA 2YT2A 5HE3A 1V5PA 3TCAA 3VOQA 1XD4A 5DIFB 2K2UA 3QWMA 3PSCA 1FGYA 3WA0A 3A58A 2DHJA 3F0WA 5L81A 2Z0QA 1X05A 5I2MA 1MK9B 1J0WA 1ZVRA 2Z0OA 3FEHA 3O96A 2CRFA 1DDVA 1U5FA 1TXDA 2K49A 3HIEA 1X1FA 1PMSA 1V89A 2D9XA 4HB0B 2LULA 1WJ1A 2UZSA 2VKIA 2W2XC 1X1GA 4MT7A 2DA0A 3A8QA 1OMWA 3BJIA 2PZ1A 2RVBB 2YS3A 4C0AA 5KCVA 2OQBA 2RUKB 1GC6A 2YT1A 2HE7A 3NWDA 3KZ1A 4YONA 1ZC3B 3PP2A 1SGHA 4KHBA 2I5CA 5HE0A 2RNRB 2K8EA 4NSWA 5JHHA 4K2PA 4K81A 2GCLA 3AU5A 3X23A 2LKOA 2D9VA 3HSAA 1V88A 4IOYX 3U12A 1XCGA 4HAZB 1U2BA 1NI2A 3TO1A 5IRSA 4KVGB 4ZRJA 2I5FA 1ZSQA 1ISNA 4MK0A 5GOWB 2DYNA 5FI0A 4TKNA 4D6WA 2X18A 5LONB 4HAWB 2K2JA 3NWFA 5C6RA 1BTKA 3ODWA 1PLSA 3AU4A 1MK7B 2L2IA 1ZYIA 3ULCA 3A98B 3OANA 4K17A 3DXCA 4KHAA 3RCPA 5D27A 1X11A 4L6EA 2R2YA 1GG3A 5HE1A 1FOEA 1U27A 1NU2A 4GXBA 4MY6A 4DX8A 5C5BA 5FI1A 2COAA 3NW8A 4HAXB 1B55A 1P3RA 3MDBC 4WJ7A 3D8EA 2EMTA 2M14A 4GOUA 2MDXA 2VSZA 4DX90 1NTYA 1UEFA 2YVCA 2YS1A 2XQNM 1RJ2A 5J3TA 2ZKMX 3VIAA 1P6SA 5D3XA 1M7EA 2UVMA 1BAKA 3KY9A 2ELBA 5C16A 4HB4B 3F5RA 4B6HA 1DYNA 4HDOA 5HE2A 1LB1A 4HATB 3FSSA 4XWXA 1UNQA 3FM8C 3SV1A 1ZC4B 2CY4A 2M38A 1N3HA 3AJ4A 4BBKA 3SYXA 4HDQA 4K2OA 1U5GA 1KZGA 1KZ7A 1MI1A 1W1GA 4YL8A 4GMXB 2RLOA 1X86A 2D9YA 3ZDTA 1WJMA 3T06A 2KR0A 2MFQA 1EF1A 1FB8A 2H7DA 1MPHA 1P5TA 3NWAA 5DH9B 4OSNA 2P0DA 1V5UA 4GMVA 1U5DA 4A6HA 2DX5A 5JP4A 1E5WA 1SHCA 4L1RA 4D0NB 3DXDA 2I1JA 3FVCA 2Z0PA 1V5MA 4KHOA 2D9WA 3G9WA 1K5DB 1UPQA 4PQ0A 2R0DA 2IYBA 2RRFA 4A6FA 1J19A 1U5EA 3QBVB 2EC1A 4HAYB 1RRPB 4EKUA 3ODXA 2KIEA 3PVWA 3TVVA 2DKPA 2Y8GA 1WVHA 2YSZA 2G35A 2J0JA 2RGNB 3ML4A 3DXEA 4F7HA 2YF0A 2VRWB 2EJ8A 2GS0A 2ROZB 4GNKB 4Z2MB 3ODOA 1FAOA 2W2WA 3U8ZA 1IRSA 2N23A 5CLLB 2COCA 2Q13A 1AWEA 4HSIA 4CHMA 3OHMB 2W2XD 1UNPA 2NZ8B 3P6AA 3WYFB 2FJUB 2ELAA 4GN1A 2DHKA 4A5KA 2LOXA 4WSFA 5EFXA 2DFKA 1KI1B 5DI9B 4A6FB 5LOPB 2GUMA 4EJNA 2ROVA 1H10A 1U29A 2KUPA 4Z2NA 2RSGA 2NBVA 5C79A 3TFMA 1ZM0A 2I1KA 1MIZB 2R09A 4Y94A 3PZDA 5KQ4A 4HAVB 4EMOA 2J0MA 2UZRA 3ULBA 1Q67A 1AQCA 1Y19B 4GZUA 3CXBB 2HTHB 4KHBB 1H4RA 1WGUA 2DN6A 1DBHA 1NTVA 3PG7A 3DCXA 4F7UP 3SNHA 2D11A 3D8FA 2IFSA 4DBBA 5D3VA 2N0YA 1Y5OA 2P0FA 2DHIA 1UPRA 5J3QA 4NY0A 2DKQA 4A6KA 2CAYA 1MAIA 1QQGA 2J0KA 1EAZA 1FGZA 4F7GA 3UZTA 4P7IA 2KIGA 3D8DA 2GJYA 3KSYA 5D3WA 1OQNA 2MKRA 2E2XA 5JHGA 5I2SA 1EVHA 2D2QA 1W1HA 3PEGA 1OY2A 1BWNA 1WI1A 2D9ZA 2P8VA 2V76A 4HB2B 4HHVA 4ZRIA 1FHOA 3IVFA 2JP2A 4GPTB 2LYDA 2DTCA 4CHJA 3HQCA 1I7AA 1M7RA 1PFJA 3N7CA 1W1DA 2J59M 1TJ6A 3KRXA 2Z13A 3PVUA 5DHAB 2YS5A 1MIXA 1MKEA 4HB3B 2L1CA 2FJLA 3P7ZA 5LG4B 1V61A 5J3YA 2D4QA 2KCJA 3V5WA 3GYPA 4QJ3B 1T77A 1WG7A 3GYOA 2QKLA 2COFA 3LJUX 2AEHA 2Z59A 4KAXB 2CY5A 3B77A 1XX0A 1GC7A 4CSQA 4OT1A 1DDWA 2ZPYA 5M4YB 2LG1A 5CLQB 3M1IB 4WVFB 4PNKA 4HAUB 1FHWA 1I2HA 3SUZA 1DROA 3NSUA 2NMBA 5JLJB 2OTXA 3HW2B 3U7DA 3PVLA 3ZVRA 2H7EA 2MWNB 1K5GB 3CIKA 4H8SA 2BCJA 4DXAB 5DHFB 4ZRKA 2D10A 1QC6A 3KRWA 3SO6A 1DDMA 4DIXA 1LW3A 1WGQA 3QIJA 2YRYA 2LOZA 1XKEA 4QJ4B 3TW1A 2DLWA 4IFSA 4TYZA 5KQ1A 4QJ5B 1EGXA 2YT0A 2GCJA 2Z4DA
chains in the Genus database with same CATH topology
2EMSA 3MPXA 2Y8FA 3A8PA 2P0HA 5D3YA 1BTNA 1Z87A 1XR0B 1TQZA 2KGXB 2K00A 2Y7BA 2DYQA 1FHXA 2QKMA 2DX1A 5C5BB 1UNRA 1XODA 2AL6A 2CODA 2ADZA 3BINA 4CYEA 3HK0A 4IAPA 5HE3A 1V5PA 3TCAA 3VOQA 1XD4A 5DIFB 2K2UA 3QWMA 3PSCA 1FGYA 3WA0A 3F0WA 2DHJA 5L81A 2Z0QA 1X05A 1MK9B 1J0WA 1ZVRA 2Z0OA 3FEHA 3O96A 2CRFA 1DDVA 1U5FA 1TXDA 1X1FA 1PMSA 1V89A 2D9XA 4HB0B 2LULA 1WJ1A 2UZSA 2VKIA 2W2XC 1X1GA 4MT7A 2DA0A 3A8QA 1OMWA 3BJIA 2PZ1A 2RVBB 2YS3A 4C0AA 5KCVA 2OQBA 2RUKB 1GC6A 2YT1A 2HE7A 3KZ1A 4YONA 1ZC3B 3PP2A 1SGHA 2I5CA 5HE0A 2RNRB 4NSWA 5JHHA 4K2PA 4K81A 2GCLA 3AU5A 3X23A 2LKOA 2D9VA 1V88A 4IOYX 1XCGA 4HAZB 1U2BA 1NI2A 3TO1A 4KVGB 4ZRJA 2I5FA 1ZSQA 1ISNA 4MK0A 5GOWB 2DYNA 5FI0A 4TKNA 2X18A 5LONB 4HAWB 2K2JA 5C6RA 1BTKA 3ODWA 1PLSA 3AU4A 1MK7B 2L2IA 3ULCA 3A98B 3OANA 4K17A 3DXCA 4KHAA 3RCPA 5D27A 1X11A 4L6EA 1GG3A 5HE1A 1FOEA 1U27A 1NU2A 4GXBA 4MY6A 4DX8A 5C5BA 5FI1A 2COAA 4HAXB 1B55A 1P3RA 3MDBC 4WJ7A 3D8EA 2EMTA 2M14A 2MDXA 2VSZA 4DX90 1NTYA 1UEFA 2YVCA 2YS1A 2XQNM 1RJ2A 5J3TA 3VIAA 1P6SA 5D3XA 1M7EA 2UVMA 1BAKA 3KY9A 2ELBA 5C16A 4HB4B 3F5RA 4B6HA 1DYNA 4HDOA 5HE2A 1LB1A 4HATB 3FSSA 4XWXA 1UNQA 3FM8C 3SV1A 1ZC4B 2CY4A 2M38A 1N3HA 3AJ4A 4BBKA 3SYXA 4HDQA 4K2OA 1U5GA 1KZGA 1KZ7A 1W1GA 4YL8A 4GMXB 2RLOA 1X86A 2D9YA 3ZDTA 1WJMA 3T06A 2MFQA 1EF1A 1FB8A 2H7DA 1MPHA 1P5TA 5DH9B 2P0DA 1V5UA 4GMVA 1U5DA 4A6HA 2DX5A 5JP4A 1E5WA 1SHCA 4D0NB 3DXDA 2I1JA 2Z0PA 1V5MA 4KHOA 2D9WA 3G9WA 1K5DB 1UPQA 4PQ0A 2R0DA 2IYBA 4A6FA 1J19A 1U5EA 3QBVB 2EC1A 4HAYB 1RRPB 4EKUA 3ODXA 3PVWA 3TVVA 2DKPA 2Y8GA 1WVHA 2YSZA 2G35A 2J0JA 2RGNB 3ML4A 3DXEA 4F7HA 2YF0A 2VRWB 2EJ8A 2GS0A 2ROZB 4Z2MB 3ODOA 1FAOA 2W2WA 3U8ZA 1IRSA 2N23A 5CLLB 2COCA 2Q13A 1AWEA 4CHMA 2W2XD 1UNPA 2NZ8B 3P6AA 3WYFB 2ELAA 4GN1A 2DHKA 4A5KA 2LOXA 4WSFA 5EFXA 2DFKA 1KI1B 5DI9B 4A6FB 5LOPB 4EJNA 2ROVA 1H10A 1U29A 2KUPA 4Z2NA 2RSGA 5C79A 3TFMA 1ZM0A 2I1KA 1MIZB 2R09A 4Y94A 3PZDA 5KQ4A 4HAVB 4EMOA 2J0MA 2UZRA 3ULBA 1Q67A 1AQCA 1Y19B 4GZUA 3CXBB 2HTHB 4KHBB 1H4RA 1WGUA 2DN6A 1DBHA 1NTVA 3PG7A 4F7UP 3SNHA 2D11A 3D8FA 2IFSA 4DBBA 5D3VA 2N0YA 1Y5OA 2P0FA 2DHIA 1UPRA 5J3QA 4NY0A 2DKQA 4A6KA 2CAYA 1MAIA 1QQGA 2J0KA 1EAZA 1FGZA 4F7GA 3UZTA 4P7IA 3D8DA 2GJYA 3KSYA 5D3WA 1OQNA 2MKRA 2E2XA 5JHGA 1EVHA 2D2QA 1W1HA 3PEGA 1OY2A 1BWNA 1WI1A 2D9ZA 2P8VA 2V76A 4HB2B 4HHVA 4ZRIA 1FHOA 3IVFA 2JP2A 4GPTB 2LYDA 2DTCA 4CHJA 3HQCA 1I7AA 1M7RA 1PFJA 3N7CA 1W1DA 2J59M 1TJ6A 3KRXA 3PVUA 5DHAB 2YS5A 1MIXA 1MKEA 4HB3B 2L1CA 2FJLA 3P7ZA 1V61A 5J3YA 2D4QA 2KCJA 3V5WA 3GYPA 1WG7A 3GYOA 2QKLA 2COFA 3LJUX 2AEHA 4KAXB 2CY5A 1XX0A 1GC7A 1DDWA 2ZPYA 2LG1A 5CLQB 3M1IB 4WVFB 4PNKA 4HAUB 1FHWA 1I2HA 3SUZA 1DROA 3NSUA 2NMBA 5JLJB 2OTXA 3HW2B 3U7DA 3PVLA 3ZVRA 2H7EA 2MWNB 1K5GB 3CIKA 4H8SA 2BCJA 4DXAB 5DHFB 4ZRKA 2D10A 1QC6A 3KRWA 3SO6A 1DDMA 1LW3A 1WGQA 3QIJA 2YRYA 2LOZA 1XKEA 3TW1A 2DLWA 4IFSA 4TYZA 5KQ1A 1EGXA 2YT0A 2GCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EMS A;  3MPX A;  2Y8F A;  3A8P A;  2P0H A;  5D3Y A;  1BTN A;  1Z87 A;  1XR0 B;  1TQZ A;  2KGX B;  2K00 A;  2Y7B A;  2DYQ A;  1FHX A;  2QKM A;  2DX1 A;  5C5B B;  1UNR A;  1XOD A;  2AL6 A;  2COD A;  2ADZ A;  3BIN A;  4CYE A;  3HK0 A;  4IAP A;  5HE3 A;  1V5P A;  3TCA A;  3VOQ A;  1XD4 A;  5DIF B;  2K2U A;  3QWM A;  3PSC A;  1FGY A;  3WA0 A;  3F0W A;  2DHJ A;  5L81 A;  2Z0Q A;  1X05 A;  1MK9 B;  1J0W A;  1ZVR A;  2Z0O A;  3FEH A;  3O96 A;  2CRF A;  1DDV A;  1U5F A;  1TXD A;  1X1F A;  1PMS A;  1V89 A;  2D9X A;  4HB0 B;  2LUL A;  1WJ1 A;  2UZS A;  2VKI A;  2W2X C;  1X1G A;  4MT7 A;  2DA0 A;  3A8Q A;  1OMW A;  3BJI A;  2PZ1 A;  2RVB B;  2YS3 A;  4C0A A;  5KCV A;  2OQB A;  2RUK B;  1GC6 A;  2YT1 A;  2HE7 A;  3KZ1 A;  4YON A;  1ZC3 B;  3PP2 A;  1SGH A;  2I5C A;  5HE0 A;  2RNR B;  4NSW A;  5JHH A;  4K2P A;  4K81 A;  2GCL A;  3AU5 A;  3X23 A;  2LKO A;  2D9V A;  1V88 A;  4IOY X;  1XCG A;  4HAZ B;  1U2B A;  1NI2 A;  3TO1 A;  4KVG B;  4ZRJ A;  2I5F A;  1ZSQ A;  1ISN A;  4MK0 A;  5GOW B;  2DYN A;  5FI0 A;  4TKN A;  2X18 A;  5LON B;  4HAW B;  2K2J A;  5C6R A;  1BTK A;  3ODW A;  1PLS A;  3AU4 A;  1MK7 B;  2L2I A;  3ULC A;  3A98 B;  3OAN A;  4K17 A;  3DXC A;  4KHA A;  3RCP A;  5D27 A;  1X11 A;  4L6E A;  1GG3 A;  5HE1 A;  1FOE A;  1U27 A;  1NU2 A;  4GXB A;  4MY6 A;  4DX8 A;  5C5B A;  5FI1 A;  2COA A;  4HAX B;  1B55 A;  1P3R A;  3MDB C;  4WJ7 A;  3D8E A;  2EMT A;  2M14 A;  2MDX A;  2VSZ A;  4DX9 0;  1NTY A;  1UEF A;  2YVC A;  2YS1 A;  2XQN M;  1RJ2 A;  5J3T A;  3VIA A;  1P6S A;  5D3X A;  1M7E A;  2UVM A;  1BAK A;  3KY9 A;  2ELB A;  5C16 A;  4HB4 B;  3F5R A;  4B6H A;  1DYN A;  4HDO A;  5HE2 A;  1LB1 A;  4HAT B;  3FSS A;  4XWX A;  1UNQ A;  3FM8 C;  3SV1 A;  1ZC4 B;  2CY4 A;  2M38 A;  1N3H A;  3AJ4 A;  4BBK A;  3SYX A;  4HDQ A;  4K2O A;  1U5G A;  1KZG A;  1KZ7 A;  1W1G A;  4YL8 A;  4GMX B;  2RLO A;  1X86 A;  2D9Y A;  3ZDT A;  1WJM A;  3T06 A;  2MFQ A;  1EF1 A;  1FB8 A;  2H7D A;  1MPH A;  1P5T A;  5DH9 B;  2P0D A;  1V5U A;  4GMV A;  1U5D A;  4A6H A;  2DX5 A;  5JP4 A;  1E5W A;  1SHC A;  4D0N B;  3DXD A;  2I1J A;  2Z0P A;  1V5M A;  4KHO A;  2D9W A;  3G9W A;  1K5D B;  1UPQ A;  4PQ0 A;  2R0D A;  2IYB A;  4A6F A;  1J19 A;  1U5E A;  3QBV B;  2EC1 A;  4HAY B;  1RRP B;  4EKU A;  3ODX A;  3PVW A;  3TVV A;  2DKP A;  2Y8G A;  1WVH A;  2YSZ A;  2G35 A;  2J0J A;  2RGN B;  3ML4 A;  3DXE A;  4F7H A;  2YF0 A;  2VRW B;  2EJ8 A;  2GS0 A;  2ROZ B;  4Z2M B;  3ODO A;  1FAO A;  2W2W A;  3U8Z A;  1IRS A;  2N23 A;  5CLL B;  2COC A;  2Q13 A;  1AWE A;  4CHM A;  2W2X D;  1UNP A;  2NZ8 B;  3P6A A;  3WYF B;  2ELA A;  4GN1 A;  2DHK A;  4A5K A;  2LOX A;  4WSF A;  5EFX A;  2DFK A;  1KI1 B;  5DI9 B;  4A6F B;  5LOP B;  4EJN A;  2ROV A;  1H10 A;  1U29 A;  2KUP A;  4Z2N A;  2RSG A;  5C79 A;  3TFM A;  1ZM0 A;  2I1K A;  1MIZ B;  2R09 A;  4Y94 A;  3PZD A;  5KQ4 A;  4HAV B;  4EMO A;  2J0M A;  2UZR A;  3ULB A;  1Q67 A;  1AQC A;  1Y19 B;  4GZU A;  3CXB B;  2HTH B;  4KHB B;  1H4R A;  1WGU A;  2DN6 A;  1DBH A;  1NTV A;  3PG7 A;  4F7U P;  3SNH A;  2D11 A;  3D8F A;  2IFS A;  4DBB A;  5D3V A;  2N0Y A;  1Y5O A;  2P0F A;  2DHI A;  1UPR A;  5J3Q A;  4NY0 A;  2DKQ A;  4A6K A;  2CAY A;  1MAI A;  1QQG A;  2J0K A;  1EAZ A;  1FGZ A;  4F7G A;  3UZT A;  4P7I A;  3D8D A;  2GJY A;  3KSY A;  5D3W A;  1OQN A;  2MKR A;  2E2X A;  5JHG A;  1EVH A;  2D2Q A;  1W1H A;  3PEG A;  1OY2 A;  1BWN A;  1WI1 A;  2D9Z A;  2P8V A;  2V76 A;  4HB2 B;  4HHV A;  4ZRI A;  1FHO A;  3IVF A;  2JP2 A;  4GPT B;  2LYD A;  2DTC A;  4CHJ A;  3HQC A;  1I7A A;  1M7R A;  1PFJ A;  3N7C A;  1W1D A;  2J59 M;  1TJ6 A;  3KRX A;  3PVU A;  5DHA B;  2YS5 A;  1MIX A;  1MKE A;  4HB3 B;  2L1C A;  2FJL A;  3P7Z A;  1V61 A;  5J3Y A;  2D4Q A;  2KCJ A;  3V5W A;  3GYP A;  1WG7 A;  3GYO A;  2QKL A;  2COF A;  3LJU X;  2AEH A;  4KAX B;  2CY5 A;  1XX0 A;  1GC7 A;  1DDW A;  2ZPY A;  2LG1 A;  5CLQ B;  3M1I B;  4WVF B;  4PNK A;  4HAU B;  1FHW A;  1I2H A;  3SUZ A;  1DRO A;  3NSU A;  2NMB A;  5JLJ B;  2OTX A;  3HW2 B;  3U7D A;  3PVL A;  3ZVR A;  2H7E A;  2MWN B;  1K5G B;  3CIK A;  4H8S A;  2BCJ A;  4DXA B;  5DHF B;  4ZRK A;  2D10 A;  1QC6 A;  3KRW A;  3SO6 A;  1DDM A;  1LW3 A;  1WGQ A;  3QIJ A;  2YRY A;  2LOZ A;  1XKE A;  3TW1 A;  2DLW A;  4IFS A;  4TYZ A;  5KQ1 A;  1EGX A;  2YT0 A;  2GCJ A; 
#chains in the Genus database with same CATH topology
 2EMS A;  3MPX A;  2Y8F A;  3A8P A;  4QXA B;  2Z14 A;  2P0H A;  5D3Y A;  1BTN A;  1Z87 A;  1XR0 B;  1TQZ A;  2KGX B;  2K00 A;  2Y7B A;  2DYQ A;  1FHX A;  2QKM A;  2DX1 A;  5C5B B;  1UNR A;  2KUQ A;  1XOD A;  2AL6 A;  2COD A;  2ADZ A;  3BIN A;  4CYE A;  3HK0 A;  4IAP A;  2YT2 A;  5HE3 A;  1V5P A;  3TCA A;  3VOQ A;  1XD4 A;  5DIF B;  2K2U A;  3QWM A;  3PSC A;  1FGY A;  3WA0 A;  3A58 A;  2DHJ A;  3F0W A;  5L81 A;  2Z0Q A;  1X05 A;  5I2M A;  1MK9 B;  1J0W A;  1ZVR A;  2Z0O A;  3FEH A;  3O96 A;  2CRF A;  1DDV A;  1U5F A;  1TXD A;  2K49 A;  3HIE A;  1X1F A;  1PMS A;  1V89 A;  2D9X A;  4HB0 B;  2LUL A;  1WJ1 A;  2UZS A;  2VKI A;  2W2X C;  1X1G A;  4MT7 A;  2DA0 A;  3A8Q A;  1OMW A;  3BJI A;  2PZ1 A;  2RVB B;  2YS3 A;  4C0A A;  5KCV A;  2OQB A;  2RUK B;  1GC6 A;  2YT1 A;  2HE7 A;  3NWD A;  3KZ1 A;  4YON A;  1ZC3 B;  3PP2 A;  1SGH A;  4KHB A;  2I5C A;  5HE0 A;  2RNR B;  2K8E A;  4NSW A;  5JHH A;  4K2P A;  4K81 A;  2GCL A;  3AU5 A;  3X23 A;  2LKO A;  2D9V A;  3HSA A;  1V88 A;  4IOY X;  3U12 A;  1XCG A;  4HAZ B;  1U2B A;  1NI2 A;  3TO1 A;  5IRS A;  4KVG B;  4ZRJ A;  2I5F A;  1ZSQ A;  1ISN A;  4MK0 A;  5GOW B;  2DYN A;  5FI0 A;  4TKN A;  4D6W A;  2X18 A;  5LON B;  4HAW B;  2K2J A;  3NWF A;  5C6R A;  1BTK A;  3ODW A;  1PLS A;  3AU4 A;  1MK7 B;  2L2I A;  1ZYI A;  3ULC A;  3A98 B;  3OAN A;  4K17 A;  3DXC A;  4KHA A;  3RCP A;  5D27 A;  1X11 A;  4L6E A;  2R2Y A;  1GG3 A;  5HE1 A;  1FOE A;  1U27 A;  1NU2 A;  4GXB A;  4MY6 A;  4DX8 A;  5C5B A;  5FI1 A;  2COA A;  3NW8 A;  4HAX B;  1B55 A;  1P3R A;  3MDB C;  4WJ7 A;  3D8E A;  2EMT A;  2M14 A;  4GOU A;  2MDX A;  2VSZ A;  4DX9 0;  1NTY A;  1UEF A;  2YVC A;  2YS1 A;  2XQN M;  1RJ2 A;  5J3T A;  2ZKM X;  3VIA A;  1P6S A;  5D3X A;  1M7E A;  2UVM A;  1BAK A;  3KY9 A;  2ELB A;  5C16 A;  4HB4 B;  3F5R A;  4B6H A;  1DYN A;  4HDO A;  5HE2 A;  1LB1 A;  4HAT B;  3FSS A;  4XWX A;  1UNQ A;  3FM8 C;  3SV1 A;  1ZC4 B;  2CY4 A;  2M38 A;  1N3H A;  3AJ4 A;  4BBK A;  3SYX A;  4HDQ A;  4K2O A;  1U5G A;  1KZG A;  1KZ7 A;  1MI1 A;  1W1G A;  4YL8 A;  4GMX B;  2RLO A;  1X86 A;  2D9Y A;  3ZDT A;  1WJM A;  3T06 A;  2KR0 A;  2MFQ A;  1EF1 A;  1FB8 A;  2H7D A;  1MPH A;  1P5T A;  3NWA A;  5DH9 B;  4OSN A;  2P0D A;  1V5U A;  4GMV A;  1U5D A;  4A6H A;  2DX5 A;  5JP4 A;  1E5W A;  1SHC A;  4L1R A;  4D0N B;  3DXD A;  2I1J A;  3FVC A;  2Z0P A;  1V5M A;  4KHO A;  2D9W A;  3G9W A;  1K5D B;  1UPQ A;  4PQ0 A;  2R0D A;  2IYB A;  2RRF A;  4A6F A;  1J19 A;  1U5E A;  3QBV B;  2EC1 A;  4HAY B;  1RRP B;  4EKU A;  3ODX A;  2KIE A;  3PVW A;  3TVV A;  2DKP A;  2Y8G A;  1WVH A;  2YSZ A;  2G35 A;  2J0J A;  2RGN B;  3ML4 A;  3DXE A;  4F7H A;  2YF0 A;  2VRW B;  2EJ8 A;  2GS0 A;  2ROZ B;  4GNK B;  4Z2M B;  3ODO A;  1FAO A;  2W2W A;  3U8Z A;  1IRS A;  2N23 A;  5CLL B;  2COC A;  2Q13 A;  1AWE A;  4HSI A;  4CHM A;  3OHM B;  2W2X D;  1UNP A;  2NZ8 B;  3P6A A;  3WYF B;  2FJU B;  2ELA A;  4GN1 A;  2DHK A;  4A5K A;  2LOX A;  4WSF A;  5EFX A;  2DFK A;  1KI1 B;  5DI9 B;  4A6F B;  5LOP B;  2GUM A;  4EJN A;  2ROV A;  1H10 A;  1U29 A;  2KUP A;  4Z2N A;  2RSG A;  2NBV A;  5C79 A;  3TFM A;  1ZM0 A;  2I1K A;  1MIZ B;  2R09 A;  4Y94 A;  3PZD A;  5KQ4 A;  4HAV B;  4EMO A;  2J0M A;  2UZR A;  3ULB A;  1Q67 A;  1AQC A;  1Y19 B;  4GZU A;  3CXB B;  2HTH B;  4KHB B;  1H4R A;  1WGU A;  2DN6 A;  1DBH A;  1NTV A;  3PG7 A;  3DCX A;  4F7U P;  3SNH A;  2D11 A;  3D8F A;  2IFS A;  4DBB A;  5D3V A;  2N0Y A;  1Y5O A;  2P0F A;  2DHI A;  1UPR A;  5J3Q A;  4NY0 A;  2DKQ A;  4A6K A;  2CAY A;  1MAI A;  1QQG A;  2J0K A;  1EAZ A;  1FGZ A;  4F7G A;  3UZT A;  4P7I A;  2KIG A;  3D8D A;  2GJY A;  3KSY A;  5D3W A;  1OQN A;  2MKR A;  2E2X A;  5JHG A;  5I2S A;  1EVH A;  2D2Q A;  1W1H A;  3PEG A;  1OY2 A;  1BWN A;  1WI1 A;  2D9Z A;  2P8V A;  2V76 A;  4HB2 B;  4HHV A;  4ZRI A;  1FHO A;  3IVF A;  2JP2 A;  4GPT B;  2LYD A;  2DTC A;  4CHJ A;  3HQC A;  1I7A A;  1M7R A;  1PFJ A;  3N7C A;  1W1D A;  2J59 M;  1TJ6 A;  3KRX A;  2Z13 A;  3PVU A;  5DHA B;  2YS5 A;  1MIX A;  1MKE A;  4HB3 B;  2L1C A;  2FJL A;  3P7Z A;  5LG4 B;  1V61 A;  5J3Y A;  2D4Q A;  2KCJ A;  3V5W A;  3GYP A;  4QJ3 B;  1T77 A;  1WG7 A;  3GYO A;  2QKL A;  2COF A;  3LJU X;  2AEH A;  2Z59 A;  4KAX B;  2CY5 A;  3B77 A;  1XX0 A;  1GC7 A;  4CSQ A;  4OT1 A;  1DDW A;  2ZPY A;  5M4Y B;  2LG1 A;  5CLQ B;  3M1I B;  4WVF B;  4PNK A;  4HAU B;  1FHW A;  1I2H A;  3SUZ A;  1DRO A;  3NSU A;  2NMB A;  5JLJ B;  2OTX A;  3HW2 B;  3U7D A;  3PVL A;  3ZVR A;  2H7E A;  2MWN B;  1K5G B;  3CIK A;  4H8S A;  2BCJ A;  4DXA B;  5DHF B;  4ZRK A;  2D10 A;  1QC6 A;  3KRW A;  3SO6 A;  1DDM A;  4DIX A;  1LW3 A;  1WGQ A;  3QIJ A;  2YRY A;  2LOZ A;  1XKE A;  4QJ4 B;  3TW1 A;  2DLW A;  4IFS A;  4TYZ A;  5KQ1 A;  4QJ5 B;  1EGX A;  2YT0 A;  2GCJ A;  2Z4D A; 
#chains in the Genus database with same CATH homology
 2EMS A;  3MPX A;  2Y8F A;  3A8P A;  2P0H A;  5D3Y A;  1BTN A;  1Z87 A;  1XR0 B;  1TQZ A;  2KGX B;  2K00 A;  2Y7B A;  2DYQ A;  1FHX A;  2QKM A;  2DX1 A;  5C5B B;  1UNR A;  1XOD A;  2AL6 A;  2COD A;  2ADZ A;  3BIN A;  4CYE A;  3HK0 A;  4IAP A;  5HE3 A;  1V5P A;  3TCA A;  3VOQ A;  1XD4 A;  5DIF B;  2K2U A;  3QWM A;  3PSC A;  1FGY A;  3WA0 A;  3F0W A;  2DHJ A;  5L81 A;  2Z0Q A;  1X05 A;  1MK9 B;  1J0W A;  1ZVR A;  2Z0O A;  3FEH A;  3O96 A;  2CRF A;  1DDV A;  1U5F A;  1TXD A;  1X1F A;  1PMS A;  1V89 A;  2D9X A;  4HB0 B;  2LUL A;  1WJ1 A;  2UZS A;  2VKI A;  2W2X C;  1X1G A;  4MT7 A;  2DA0 A;  3A8Q A;  1OMW A;  3BJI A;  2PZ1 A;  2RVB B;  2YS3 A;  4C0A A;  5KCV A;  2OQB A;  2RUK B;  1GC6 A;  2YT1 A;  2HE7 A;  3KZ1 A;  4YON A;  1ZC3 B;  3PP2 A;  1SGH A;  2I5C A;  5HE0 A;  2RNR B;  4NSW A;  5JHH A;  4K2P A;  4K81 A;  2GCL A;  3AU5 A;  3X23 A;  2LKO A;  2D9V A;  1V88 A;  4IOY X;  1XCG A;  4HAZ B;  1U2B A;  1NI2 A;  3TO1 A;  4KVG B;  4ZRJ A;  2I5F A;  1ZSQ A;  1ISN A;  4MK0 A;  5GOW B;  2DYN A;  5FI0 A;  4TKN A;  2X18 A;  5LON B;  4HAW B;  2K2J A;  5C6R A;  1BTK A;  3ODW A;  1PLS A;  3AU4 A;  1MK7 B;  2L2I A;  3ULC A;  3A98 B;  3OAN A;  4K17 A;  3DXC A;  4KHA A;  3RCP A;  5D27 A;  1X11 A;  4L6E A;  1GG3 A;  5HE1 A;  1FOE A;  1U27 A;  1NU2 A;  4GXB A;  4MY6 A;  4DX8 A;  5C5B A;  5FI1 A;  2COA A;  4HAX B;  1B55 A;  1P3R A;  3MDB C;  4WJ7 A;  3D8E A;  2EMT A;  2M14 A;  2MDX A;  2VSZ A;  4DX9 0;  1NTY A;  1UEF A;  2YVC A;  2YS1 A;  2XQN M;  1RJ2 A;  5J3T A;  3VIA A;  1P6S A;  5D3X A;  1M7E A;  2UVM A;  1BAK A;  3KY9 A;  2ELB A;  5C16 A;  4HB4 B;  3F5R A;  4B6H A;  1DYN A;  4HDO A;  5HE2 A;  1LB1 A;  4HAT B;  3FSS A;  4XWX A;  1UNQ A;  3FM8 C;  3SV1 A;  1ZC4 B;  2CY4 A;  2M38 A;  1N3H A;  3AJ4 A;  4BBK A;  3SYX A;  4HDQ A;  4K2O A;  1U5G A;  1KZG A;  1KZ7 A;  1W1G A;  4YL8 A;  4GMX B;  2RLO A;  1X86 A;  2D9Y A;  3ZDT A;  1WJM A;  3T06 A;  2MFQ A;  1EF1 A;  1FB8 A;  2H7D A;  1MPH A;  1P5T A;  5DH9 B;  2P0D A;  1V5U A;  4GMV A;  1U5D A;  4A6H A;  2DX5 A;  5JP4 A;  1E5W A;  1SHC A;  4D0N B;  3DXD A;  2I1J A;  2Z0P A;  1V5M A;  4KHO A;  2D9W A;  3G9W A;  1K5D B;  1UPQ A;  4PQ0 A;  2R0D A;  2IYB A;  4A6F A;  1J19 A;  1U5E A;  3QBV B;  2EC1 A;  4HAY B;  1RRP B;  4EKU A;  3ODX A;  3PVW A;  3TVV A;  2DKP A;  2Y8G A;  1WVH A;  2YSZ A;  2G35 A;  2J0J A;  2RGN B;  3ML4 A;  3DXE A;  4F7H A;  2YF0 A;  2VRW B;  2EJ8 A;  2GS0 A;  2ROZ B;  4Z2M B;  3ODO A;  1FAO A;  2W2W A;  3U8Z A;  1IRS A;  2N23 A;  5CLL B;  2COC A;  2Q13 A;  1AWE A;  4CHM A;  2W2X D;  1UNP A;  2NZ8 B;  3P6A A;  3WYF B;  2ELA A;  4GN1 A;  2DHK A;  4A5K A;  2LOX A;  4WSF A;  5EFX A;  2DFK A;  1KI1 B;  5DI9 B;  4A6F B;  5LOP B;  4EJN A;  2ROV A;  1H10 A;  1U29 A;  2KUP A;  4Z2N A;  2RSG A;  5C79 A;  3TFM A;  1ZM0 A;  2I1K A;  1MIZ B;  2R09 A;  4Y94 A;  3PZD A;  5KQ4 A;  4HAV B;  4EMO A;  2J0M A;  2UZR A;  3ULB A;  1Q67 A;  1AQC A;  1Y19 B;  4GZU A;  3CXB B;  2HTH B;  4KHB B;  1H4R A;  1WGU A;  2DN6 A;  1DBH A;  1NTV A;  3PG7 A;  4F7U P;  3SNH A;  2D11 A;  3D8F A;  2IFS A;  4DBB A;  5D3V A;  2N0Y A;  1Y5O A;  2P0F A;  2DHI A;  1UPR A;  5J3Q A;  4NY0 A;  2DKQ A;  4A6K A;  2CAY A;  1MAI A;  1QQG A;  2J0K A;  1EAZ A;  1FGZ A;  4F7G A;  3UZT A;  4P7I A;  3D8D A;  2GJY A;  3KSY A;  5D3W A;  1OQN A;  2MKR A;  2E2X A;  5JHG A;  1EVH A;  2D2Q A;  1W1H A;  3PEG A;  1OY2 A;  1BWN A;  1WI1 A;  2D9Z A;  2P8V A;  2V76 A;  4HB2 B;  4HHV A;  4ZRI A;  1FHO A;  3IVF A;  2JP2 A;  4GPT B;  2LYD A;  2DTC A;  4CHJ A;  3HQC A;  1I7A A;  1M7R A;  1PFJ A;  3N7C A;  1W1D A;  2J59 M;  1TJ6 A;  3KRX A;  3PVU A;  5DHA B;  2YS5 A;  1MIX A;  1MKE A;  4HB3 B;  2L1C A;  2FJL A;  3P7Z A;  1V61 A;  5J3Y A;  2D4Q A;  2KCJ A;  3V5W A;  3GYP A;  1WG7 A;  3GYO A;  2QKL A;  2COF A;  3LJU X;  2AEH A;  4KAX B;  2CY5 A;  1XX0 A;  1GC7 A;  1DDW A;  2ZPY A;  2LG1 A;  5CLQ B;  3M1I B;  4WVF B;  4PNK A;  4HAU B;  1FHW A;  1I2H A;  3SUZ A;  1DRO A;  3NSU A;  2NMB A;  5JLJ B;  2OTX A;  3HW2 B;  3U7D A;  3PVL A;  3ZVR A;  2H7E A;  2MWN B;  1K5G B;  3CIK A;  4H8S A;  2BCJ A;  4DXA B;  5DHF B;  4ZRK A;  2D10 A;  1QC6 A;  3KRW A;  3SO6 A;  1DDM A;  1LW3 A;  1WGQ A;  3QIJ A;  2YRY A;  2LOZ A;  1XKE A;  3TW1 A;  2DLW A;  4IFS A;  4TYZ A;  5KQ1 A;  1EGX A;  2YT0 A;  2GCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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