5DBYA

Crystal structure of equine serum albumin in complex with diclofenac and naproxen obtained in displacement experiment
Total Genus 238
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
238
sequence length
580
structure length
580
Chain Sequence
KSEIAHRFNDLGEKHFKGLVLVAFSQYLQQCPFEDHVKLVNEVTEFAKKCAADESAENCDKSLHTLFGDKLCTVATLRATYGELADCCEKQEPERNECFLTHKDDHPNLPKLKPEPDAQCAAFQEDPDKFLGKYLYEVARRHPYFYGPELLFHAEEYKADFTECCPADDKAGCLIPKLDALKERILLSSAKERLKCSSFQNFGERAVKAWSVARLSQKFPKADFAEVSKIVTDLTKVHKECCHGDLLECADDRADLAKYICEHQDSISGKLKACCDKPLLQKSHCIAEVKEDDLPSDLPALAADFAEDKEICKHYKDAKDVFLGTFLYEYSRRHPDYSVSLLLRIAKTYEATLEKCCAEADPPACYATVFDQFTPLVEEPKSLVKKNCDLFEEVGEYDFQNALIVRYTKKAPQVSTPTLVEIGRTLGKVGSRCCKLPESERLPCSENHLALALNRLCVLHEKTPVSEKITKCCTDSLAERRPCFSALELDEGYVPKEFKAETFTFHADICTLPEDEKQIKKQSALAELVKHKPKATKEQLKTVLGNFSAFVAKCCGAEDKEACFAEEGPKLVASSQLALA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Serum albumin
publication title Structural Insights into the Competitive Binding of Diclofenac and Naproxen by Equine Serum Albumin.
pubmed doi rcsb
molecule tags Transport protein
total genus 238
structure length 580
sequence length 580
ec nomenclature
pdb deposition date 2015-08-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 5dbyA05
4L9KA 3V03A 3V09A 4PO0A 1KXPD 1N5UA 2BXBA 1O9XA 1BJ5A 4L9QA 2BXGA 2VUEA 5IIUA 4F5SA 2BXKA 3TDLA 5GHKA 4HGMB 4OR0A 4LB9A 4IW1A 3SQJA 1J7EA 4L8UA 2BXPA 1E7GA 2BXNA 2VDBA 2VUFA 2BXLA 2BXQA 2BXDA 5ID7A 4HGKA 3CX9A 1TF0A 5DBYA 5IJEA 4OT2A 5HOZA 1HK5A 4J2VA 3JQZA 4LUHA 1E7CA 2I2ZA 1KW2A 2XW1A 2BXMA 5IJ5A 3LU8A 4IW2A 2I30A 1E7HA 5DQFA 1HK1A 4E99A 5IIHA 5IJFA 4F5TA 3B9LA 4ZBRA 4Z69A 1HK2A 1E7AA 1E7FA 4EMXA 1E7BA 2YDFA 1J78A 4LA0A 1AO6A 1E78A 1H9ZA 4K71A 2BXHA 2XVWA 1LOTA 1HK4A 3UIVA 1BM0A 5FUOA 5IIXA 4F5UA 4ZBQA 1HK3A 3B9MA 5ID9A 3V08A 4JK4A 3LU6A 4K2CA 2XVQA 5IFOA 2BXEA 2BX8A 3JRYA 4N0FD 1BKEA 4LUFA 3A73A 2BXCA 1HA2A 2BXAA 4F5VA 1MA9A 4G04A 2BXFA 4BKEA 1E7IA 2XW0A 1GNJA 3LU7A 2BXIA 2XVUA 1UORA 2XVVA 2BXOA 4S1YA 4N0UD 4LB2A 2XSIA 1GNIA 1E7EA 4G03A
chains in the Genus database with same CATH superfamily
3PLAA 5GINA 4L9KA 1IJGA 3V03A 3MHSB 1MIYA 3V09A 4PO0A 4D7XA 1KXPD 2GUTA 1MIWA 1N5UA 3H3AA 4OTTA 2BXBA 1O9XA 1MUSA 1BJ5A 4L9QA 5GIOA 2BXGA 2DBXA 2K0NA 2VUEA 1FOUA 3SIUB 4FIPB 5IIUA 4F5SA 2BXKA 3M99C 3TDLA 4G01A 3NVMA 5GHKA 4HGMB 5GIPA 1LNSA 4LB9A 4IW1A 4OR0A 4ZBKA 3W1SA 3SQJA 2LQIA 3WHRA 4ZCGA 4OTUA 1J7EA 3MHHB 2EFHA 4L8UA 2BXPA 1E7GA 2AJEA 2BXNA 2VDBA 2VUFA 2BXLA 2BXQA 2BXDA 3FWCC 3NMUA 5ID7A 3NVKA 2Z8IA 4HGKA 2EFEA 3CX9A 3SIVB 1TF0A 5DBYA 5IJEA 4OT2A 3WHSA 2CKXA 1HK5A 3GQUA 4J2VA 2LQHA 5HOZA 3JQZA 2QHBA 2ROHA 4LUHA 3VQIA 4GDLB 3FWBC 1E7CA 2I2ZA 1KDXA 1KW2A 2XW1A 3KJLA 2BXMA 1NT2B 3KIKA 3BPJA 5IJ5A 3H37A 3LU8A 4I9OA 4IW2A 2QMCA 4W4UB 3WHQA 2I30A 1E7HA 5DQFA 1HK1A 4E99A 5IIHA 4NAWB 5IJFA 4GG2A 2KBZA 4FK5B 4F5TA 3B9LA 4ZBRA 2DG5A 2QM6A 4TQ0A 2JUHA 3GA9L 4Z69A 2DYOA 2V36A 1HK2A 1E7AA 4ZC6A 2AGHB 1VZSA 2E0XA 1E7FA 4WA6B 2Z8JA 1JNBA 5D7GA 4EMXA 2NNWA 1E7BA 4DHXB 3FNMA 2DYMA 3ECPA 2YDFA 2KWFA 2EFDA 3NVIA 1J78A 4LA0A 2EFCA 1AO6A 1E78A 1H9ZA 5B5TA 1MIVA 4K71A 2BXHA 2XVWA 2Z8KA 4GDKB 4M70B 1LOTA 1HK4A 3UIVA 1BM0A 5FUOA 4GDXA 3GQXA 5IIXA 4F5UA 4FJCB 1HK3A 4ZBQA 3B9MA 5ID9A 3V08A 4JK4A 3LU6A 4K2CA 1VFIA 4BY9C 2XVQA 5IFOA 1SB0A 2BXEA 4N3ZA 2BX8A 2E0YA 3JRYA 4DM0A 4N0FD 1BKEA 4TQ1A 2DBUA 4LUFA 2XMOA 1MUHA 3A73A 2OT3A 2LXTA 2BXCA 3G9KD 1HA2A 2BXAA 4F5VA 1MA9A 4G04A 2BXFA 4BKEA 1E7IA 2XW0A 2LXSA 1GNJA 3LU7A 4ZUXV 1H5WA 2BXIA 2XVUA 1UORA 2XVVA 2DBWA 3A75A 2BXOA 1TXUA 2NQOA 4MBEC 4S1YA 4N0UD 4Z9OA 5BPKA 1MM8A 2OZBB 4LB2A 4C31B 2XSIA 1GNIA 2LOQA 3ICXA 1E7EA 4G03A
chains in the Genus database with same CATH topology
3PLAA 5GINA 4L9KA 1IJGA 3V03A 3MHSB 1MIYA 3V09A 4PO0A 1KXPD 1MIWA 1N5UA 3H3AA 4OTTA 2BXBA 1O9XA 1BJ5A 4L9QA 5GIOA 2BXGA 2DBXA 2VUEA 1FOUA 3SIUB 4FIPB 5IIUA 4F5SA 2BXKA 3M99C 3TDLA 4G01A 3NVMA 5GHKA 4HGMB 5GIPA 1LNSA 4LB9A 4IW1A 4OR0A 4ZBKA 3W1SA 3SQJA 3WHRA 4ZCGA 4OTUA 1J7EA 3MHHB 2EFHA 4L8UA 2BXPA 1E7GA 2AJEA 2BXNA 2VDBA 2VUFA 2BXLA 2BXQA 2BXDA 3FWCC 3NMUA 5ID7A 3NVKA 2Z8IA 4HGKA 2EFEA 3CX9A 3SIVB 1TF0A 5DBYA 5IJEA 4OT2A 3WHSA 2CKXA 1HK5A 3GQUA 4J2VA 5HOZA 3JQZA 2QHBA 2ROHA 4LUHA 3VQIA 4GDLB 3FWBC 1E7CA 2I2ZA 1KW2A 2XW1A 3KJLA 2BXMA 1NT2B 3KIKA 5IJ5A 3H37A 3LU8A 4IW2A 2QMCA 4W4UB 3WHQA 2I30A 1E7HA 5DQFA 1HK1A 4E99A 5IIHA 4NAWB 5IJFA 4GG2A 2KBZA 4FK5B 4F5TA 3B9LA 4ZBRA 2DG5A 2QM6A 4TQ0A 2JUHA 3GA9L 4Z69A 2DYOA 2V36A 1HK2A 1E7AA 4ZC6A 1VZSA 2E0XA 1E7FA 4WA6B 2Z8JA 1JNBA 5D7GA 4EMXA 2NNWA 1E7BA 4DHXB 3FNMA 2DYMA 2YDFA 2EFDA 3NVIA 1J78A 4LA0A 2EFCA 1AO6A 1E78A 1H9ZA 5B5TA 1MIVA 4K71A 2BXHA 2XVWA 2Z8KA 4GDKB 4M70B 1LOTA 1HK4A 3UIVA 1BM0A 5FUOA 4GDXA 3GQXA 5IIXA 4F5UA 4FJCB 1HK3A 4ZBQA 3B9MA 5ID9A 3V08A 4JK4A 3LU6A 4K2CA 1VFIA 4BY9C 2XVQA 5IFOA 2BXEA 4N3ZA 2BX8A 2E0YA 3JRYA 4N0FD 1BKEA 4TQ1A 2DBUA 4LUFA 2XMOA 3A73A 2OT3A 2BXCA 3G9KD 1HA2A 2BXAA 4F5VA 1MA9A 4G04A 2BXFA 4BKEA 1E7IA 2XW0A 1GNJA 3LU7A 4ZUXV 1H5WA 2BXIA 2XVUA 1UORA 2XVVA 2DBWA 3A75A 2BXOA 1TXUA 2NQOA 4MBEC 4S1YA 4N0UD 4Z9OA 5BPKA 2OZBB 4LB2A 4C31B 2XSIA 1GNIA 2LOQA 3ICXA 1E7EA 4G03A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L9K A;  3V03 A;  3V09 A;  4PO0 A;  1KXP D;  1N5U A;  2BXB A;  1O9X A;  1BJ5 A;  4L9Q A;  2BXG A;  2VUE A;  5IIU A;  4F5S A;  2BXK A;  3TDL A;  5GHK A;  4HGM B;  4OR0 A;  4LB9 A;  4IW1 A;  3SQJ A;  1J7E A;  4L8U A;  2BXP A;  1E7G A;  2BXN A;  2VDB A;  2VUF A;  2BXL A;  2BXQ A;  2BXD A;  5ID7 A;  4HGK A;  3CX9 A;  1TF0 A;  5DBY A;  5IJE A;  4OT2 A;  5HOZ A;  1HK5 A;  4J2V A;  3JQZ A;  4LUH A;  1E7C A;  2I2Z A;  1KW2 A;  2XW1 A;  2BXM A;  5IJ5 A;  3LU8 A;  4IW2 A;  2I30 A;  1E7H A;  5DQF A;  1HK1 A;  4E99 A;  5IIH A;  5IJF A;  4F5T A;  3B9L A;  4ZBR A;  4Z69 A;  1HK2 A;  1E7A A;  1E7F A;  4EMX A;  1E7B A;  2YDF A;  1J78 A;  4LA0 A;  1AO6 A;  1E78 A;  1H9Z A;  4K71 A;  2BXH A;  2XVW A;  1LOT A;  1HK4 A;  3UIV A;  1BM0 A;  5FUO A;  5IIX A;  4F5U A;  4ZBQ A;  1HK3 A;  3B9M A;  5ID9 A;  3V08 A;  4JK4 A;  3LU6 A;  4K2C A;  2XVQ A;  5IFO A;  2BXE A;  2BX8 A;  3JRY A;  4N0F D;  1BKE A;  4LUF A;  3A73 A;  2BXC A;  1HA2 A;  2BXA A;  4F5V A;  1MA9 A;  4G04 A;  2BXF A;  4BKE A;  1E7I A;  2XW0 A;  1GNJ A;  3LU7 A;  2BXI A;  2XVU A;  1UOR A;  2XVV A;  2BXO A;  4S1Y A;  4N0U D;  4LB2 A;  2XSI A;  1GNI A;  1E7E A;  4G03 A; 
#chains in the Genus database with same CATH topology
 3PLA A;  5GIN A;  4L9K A;  1IJG A;  3V03 A;  3MHS B;  1MIY A;  3V09 A;  4PO0 A;  4D7X A;  1KXP D;  2GUT A;  1MIW A;  1N5U A;  3H3A A;  4OTT A;  2BXB A;  1O9X A;  1MUS A;  1BJ5 A;  4L9Q A;  5GIO A;  2BXG A;  2DBX A;  2K0N A;  2VUE A;  1FOU A;  3SIU B;  4FIP B;  5IIU A;  4F5S A;  2BXK A;  3M99 C;  3TDL A;  4G01 A;  3NVM A;  5GHK A;  4HGM B;  5GIP A;  1LNS A;  4LB9 A;  4IW1 A;  4OR0 A;  4ZBK A;  3W1S A;  3SQJ A;  2LQI A;  3WHR A;  4ZCG A;  4OTU A;  1J7E A;  3MHH B;  2EFH A;  4L8U A;  2BXP A;  1E7G A;  2AJE A;  2BXN A;  2VDB A;  2VUF A;  2BXL A;  2BXQ A;  2BXD A;  3FWC C;  3NMU A;  5ID7 A;  3NVK A;  2Z8I A;  4HGK A;  2EFE A;  3CX9 A;  3SIV B;  1TF0 A;  5DBY A;  5IJE A;  4OT2 A;  3WHS A;  2CKX A;  1HK5 A;  3GQU A;  4J2V A;  2LQH A;  5HOZ A;  3JQZ A;  2QHB A;  2ROH A;  4LUH A;  3VQI A;  4GDL B;  3FWB C;  1E7C A;  2I2Z A;  1KDX A;  1KW2 A;  2XW1 A;  3KJL A;  2BXM A;  1NT2 B;  3KIK A;  3BPJ A;  5IJ5 A;  3H37 A;  3LU8 A;  4I9O A;  4IW2 A;  2QMC A;  4W4U B;  3WHQ A;  2I30 A;  1E7H A;  5DQF A;  1HK1 A;  4E99 A;  5IIH A;  4NAW B;  5IJF A;  4GG2 A;  2KBZ A;  4FK5 B;  4F5T A;  3B9L A;  4ZBR A;  2DG5 A;  2QM6 A;  4TQ0 A;  2JUH A;  3GA9 L;  4Z69 A;  2DYO A;  2V36 A;  1HK2 A;  1E7A A;  4ZC6 A;  2AGH B;  1VZS A;  2E0X A;  1E7F A;  4WA6 B;  2Z8J A;  1JNB A;  5D7G A;  4EMX A;  2NNW A;  1E7B A;  4DHX B;  3FNM A;  2DYM A;  3ECP A;  2YDF A;  2KWF A;  2EFD A;  3NVI A;  1J78 A;  4LA0 A;  2EFC A;  1AO6 A;  1E78 A;  1H9Z A;  5B5T A;  1MIV A;  4K71 A;  2BXH A;  2XVW A;  2Z8K A;  4GDK B;  4M70 B;  1LOT A;  1HK4 A;  3UIV A;  1BM0 A;  5FUO A;  4GDX A;  3GQX A;  5IIX A;  4F5U A;  4FJC B;  1HK3 A;  4ZBQ A;  3B9M A;  5ID9 A;  3V08 A;  4JK4 A;  3LU6 A;  4K2C A;  1VFI A;  4BY9 C;  2XVQ A;  5IFO A;  1SB0 A;  2BXE A;  4N3Z A;  2BX8 A;  2E0Y A;  3JRY A;  4DM0 A;  4N0F D;  1BKE A;  4TQ1 A;  2DBU A;  4LUF A;  2XMO A;  1MUH A;  3A73 A;  2OT3 A;  2LXT A;  2BXC A;  3G9K D;  1HA2 A;  2BXA A;  4F5V A;  1MA9 A;  4G04 A;  2BXF A;  4BKE A;  1E7I A;  2XW0 A;  2LXS A;  1GNJ A;  3LU7 A;  4ZUX V;  1H5W A;  2BXI A;  2XVU A;  1UOR A;  2XVV A;  2DBW A;  3A75 A;  2BXO A;  1TXU A;  2NQO A;  4MBE C;  4S1Y A;  4N0U D;  4Z9O A;  5BPK A;  1MM8 A;  2OZB B;  4LB2 A;  4C31 B;  2XSI A;  1GNI A;  2LOQ A;  3ICX A;  1E7E A;  4G03 A; 
#chains in the Genus database with same CATH homology
 3PLA A;  5GIN A;  4L9K A;  1IJG A;  3V03 A;  3MHS B;  1MIY A;  3V09 A;  4PO0 A;  1KXP D;  1MIW A;  1N5U A;  3H3A A;  4OTT A;  2BXB A;  1O9X A;  1BJ5 A;  4L9Q A;  5GIO A;  2BXG A;  2DBX A;  2VUE A;  1FOU A;  3SIU B;  4FIP B;  5IIU A;  4F5S A;  2BXK A;  3M99 C;  3TDL A;  4G01 A;  3NVM A;  5GHK A;  4HGM B;  5GIP A;  1LNS A;  4LB9 A;  4IW1 A;  4OR0 A;  4ZBK A;  3W1S A;  3SQJ A;  3WHR A;  4ZCG A;  4OTU A;  1J7E A;  3MHH B;  2EFH A;  4L8U A;  2BXP A;  1E7G A;  2AJE A;  2BXN A;  2VDB A;  2VUF A;  2BXL A;  2BXQ A;  2BXD A;  3FWC C;  3NMU A;  5ID7 A;  3NVK A;  2Z8I A;  4HGK A;  2EFE A;  3CX9 A;  3SIV B;  1TF0 A;  5DBY A;  5IJE A;  4OT2 A;  3WHS A;  2CKX A;  1HK5 A;  3GQU A;  4J2V A;  5HOZ A;  3JQZ A;  2QHB A;  2ROH A;  4LUH A;  3VQI A;  4GDL B;  3FWB C;  1E7C A;  2I2Z A;  1KW2 A;  2XW1 A;  3KJL A;  2BXM A;  1NT2 B;  3KIK A;  5IJ5 A;  3H37 A;  3LU8 A;  4IW2 A;  2QMC A;  4W4U B;  3WHQ A;  2I30 A;  1E7H A;  5DQF A;  1HK1 A;  4E99 A;  5IIH A;  4NAW B;  5IJF A;  4GG2 A;  2KBZ A;  4FK5 B;  4F5T A;  3B9L A;  4ZBR A;  2DG5 A;  2QM6 A;  4TQ0 A;  2JUH A;  3GA9 L;  4Z69 A;  2DYO A;  2V36 A;  1HK2 A;  1E7A A;  4ZC6 A;  1VZS A;  2E0X A;  1E7F A;  4WA6 B;  2Z8J A;  1JNB A;  5D7G A;  4EMX A;  2NNW A;  1E7B A;  4DHX B;  3FNM A;  2DYM A;  2YDF A;  2EFD A;  3NVI A;  1J78 A;  4LA0 A;  2EFC A;  1AO6 A;  1E78 A;  1H9Z A;  5B5T A;  1MIV A;  4K71 A;  2BXH A;  2XVW A;  2Z8K A;  4GDK B;  4M70 B;  1LOT A;  1HK4 A;  3UIV A;  1BM0 A;  5FUO A;  4GDX A;  3GQX A;  5IIX A;  4F5U A;  4FJC B;  1HK3 A;  4ZBQ A;  3B9M A;  5ID9 A;  3V08 A;  4JK4 A;  3LU6 A;  4K2C A;  1VFI A;  4BY9 C;  2XVQ A;  5IFO A;  2BXE A;  4N3Z A;  2BX8 A;  2E0Y A;  3JRY A;  4N0F D;  1BKE A;  4TQ1 A;  2DBU A;  4LUF A;  2XMO A;  3A73 A;  2OT3 A;  2BXC A;  3G9K D;  1HA2 A;  2BXA A;  4F5V A;  1MA9 A;  4G04 A;  2BXF A;  4BKE A;  1E7I A;  2XW0 A;  1GNJ A;  3LU7 A;  4ZUX V;  1H5W A;  2BXI A;  2XVU A;  1UOR A;  2XVV A;  2DBW A;  3A75 A;  2BXO A;  1TXU A;  2NQO A;  4MBE C;  4S1Y A;  4N0U D;  4Z9O A;  5BPK A;  2OZB B;  4LB2 A;  4C31 B;  2XSI A;  1GNI A;  2LOQ A;  3ICX A;  1E7E A;  4G03 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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