5DMJA

Structure of the extracellular domain of the cd40 in complex with 3h56-5 dab
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
165
structure length
165
Chain Sequence
TACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSDVSSAFEKCHPWTSCETKDLVVQQAGTDKTDVVCGP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system/signaling protein
molecule keywords Tumor necrosis factor receptor superfamily member 5
publication title Functional Antagonism of Human CD40 Achieved by Targeting a Unique Species-Specific Epitope.
pubmed doi rcsb
source organism Homo sapiens
total genus 21
structure length 165
sequence length 165
chains with identical sequence D, F
ec nomenclature
pdb deposition date 2015-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5dmjA01
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 5dmjA02
3ALQR 4M4RA 1D4VA 5CIRE 3ME2R 5BNQR 1D0GR 3TJEF 1EXTA 1ZA3R 3MI8D 3K51B 3QBQB 3U3PA 3FL7A 2AW2B 3U3VA 4MXWR 2UWIA 3IJ2X 5DMJA 1NCFA 3ME4A 3WVTA 1JMAB 3MHDD 3U3QA 4J6GC 3QO4A 4BK4A 4FHQA 3BUKC 3U3TA 1DU3A 4M4PA 4YN0A 3URFZ 4E4DR 4GIQR 5IHLA 4MSVB 1SG1X 3MBWA 2X10A 1TNRR 3X3FA 2HEVR 4KGGC 2H9GR 4N90R 4BK5A 5L36B 3THMF 2HEYR 3QD6R 3U3SA 4RSUD 4OD2S 4I9XC 1FT4A 4KGQC
chains in the Genus database with same CATH superfamily
3ALQR 4M4RA 1D4VA 5CIRE 3ME2R 5BNQR 1D0GR 3TJEF 1EXTA 1ZA3R 3MI8D 2E4YA 3K51B 3QBQB 3U3PA 2AW2B 2QR6A 3FL7A 4MXWR 2UWIA 3IJ2X 3U3VA 5DMJA 1NCFA 3ME4A 3WVTA 1JMAB 3MHDD 3U3QA 2E4VA 4J6GC 3QO4A 4BK4A 2E4XA 4FHQA 2E4WA 3BUKC 3U3TA 1DU3A 4M4PA 4YN0A 3URFZ 4E4DR 4GIQR 5IHLA 4MSVB 1SG1X 3MBWA 2X10A 1TNRR 3X3FA 2HEVR 4KGGC 2E4UA 2H9GR 4N90R 4BK5A 5L36B 3THMF 2HEYR 3QD6R 3U3SA 4RSUD 4OD2S 4I9XC 1FT4A 4KGQC
chains in the Genus database with same CATH topology
3ALQR 4M4RA 1D4VA 5CIRE 3ME2R 5BNQR 1D0GR 3TJEF 1EXTA 1ZA3R 3MI8D 3K51B 3QBQB 3U3PA 3FL7A 2AW2B 3U3VA 4MXWR 2UWIA 3IJ2X 5DMJA 1NCFA 3ME4A 3WVTA 1JMAB 3MHDD 3U3QA 4J6GC 3QO4A 4BK4A 4FHQA 3BUKC 3U3TA 1DU3A 4M4PA 4YN0A 3URFZ 4E4DR 4GIQR 5IHLA 4MSVB 1SG1X 3MBWA 2X10A 1TNRR 3X3FA 2HEVR 4KGGC 2H9GR 4N90R 4BK5A 5L36B 3THMF 2HEYR 3QD6R 3U3SA 4RSUD 4OD2S 4I9XC 1FT4A 4KGQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ALQ R;  4M4R A;  1D4V A;  5CIR E;  3ME2 R;  5BNQ R;  1D0G R;  3TJE F;  1EXT A;  1ZA3 R;  3MI8 D;  3K51 B;  3QBQ B;  3U3P A;  3FL7 A;  2AW2 B;  3U3V A;  4MXW R;  2UWI A;  3IJ2 X;  5DMJ A;  1NCF A;  3ME4 A;  3WVT A;  1JMA B;  3MHD D;  3U3Q A;  4J6G C;  3QO4 A;  4BK4 A;  4FHQ A;  3BUK C;  3U3T A;  1DU3 A;  4M4P A;  4YN0 A;  3URF Z;  4E4D R;  4GIQ R;  5IHL A;  4MSV B;  1SG1 X;  3MBW A;  2X10 A;  1TNR R;  3X3F A;  2HEV R;  4KGG C;  2H9G R;  4N90 R;  4BK5 A;  5L36 B;  3THM F;  2HEY R;  3QD6 R;  3U3S A;  4RSU D;  4OD2 S;  4I9X C;  1FT4 A;  4KGQ C; 
#chains in the Genus database with same CATH topology
 3ALQ R;  4M4R A;  1D4V A;  5CIR E;  3ME2 R;  5BNQ R;  1D0G R;  3TJE F;  1EXT A;  1ZA3 R;  3MI8 D;  2E4Y A;  3K51 B;  3QBQ B;  3U3P A;  2AW2 B;  2QR6 A;  3FL7 A;  4MXW R;  2UWI A;  3IJ2 X;  3U3V A;  5DMJ A;  1NCF A;  3ME4 A;  3WVT A;  1JMA B;  3MHD D;  3U3Q A;  2E4V A;  4J6G C;  3QO4 A;  4BK4 A;  2E4X A;  4FHQ A;  2E4W A;  3BUK C;  3U3T A;  1DU3 A;  4M4P A;  4YN0 A;  3URF Z;  4E4D R;  4GIQ R;  5IHL A;  4MSV B;  1SG1 X;  3MBW A;  2X10 A;  1TNR R;  3X3F A;  2HEV R;  4KGG C;  2E4U A;  2H9G R;  4N90 R;  4BK5 A;  5L36 B;  3THM F;  2HEY R;  3QD6 R;  3U3S A;  4RSU D;  4OD2 S;  4I9X C;  1FT4 A;  4KGQ C; 
#chains in the Genus database with same CATH homology
 3ALQ R;  4M4R A;  1D4V A;  5CIR E;  3ME2 R;  5BNQ R;  1D0G R;  3TJE F;  1EXT A;  1ZA3 R;  3MI8 D;  3K51 B;  3QBQ B;  3U3P A;  3FL7 A;  2AW2 B;  3U3V A;  4MXW R;  2UWI A;  3IJ2 X;  5DMJ A;  1NCF A;  3ME4 A;  3WVT A;  1JMA B;  3MHD D;  3U3Q A;  4J6G C;  3QO4 A;  4BK4 A;  4FHQ A;  3BUK C;  3U3T A;  1DU3 A;  4M4P A;  4YN0 A;  3URF Z;  4E4D R;  4GIQ R;  5IHL A;  4MSV B;  1SG1 X;  3MBW A;  2X10 A;  1TNR R;  3X3F A;  2HEV R;  4KGG C;  2H9G R;  4N90 R;  4BK5 A;  5L36 B;  3THM F;  2HEY R;  3QD6 R;  3U3S A;  4RSU D;  4OD2 S;  4I9X C;  1FT4 A;  4KGQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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