5DNXA

Crystal structure of igpd from pyrococcus furiosus in complex with (r)-c348
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
176
structure length
176
Chain Sequence
MRRTTKETDIIVEIGKKGEIKTNDLILDHMLTAFAFYLGKDMRITATYDLRHHLWEDIGITLGEALRENLPEKFTRFGNAIMPMDDALVLVSVDISNRPYANVDVNIKDAEEGFAVSLLKEFVWGLARGLRATIHIKQLSGENAHHIVEAAFKGLGMALRVATKESERVESTKGVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.
pubmed doi rcsb
molecule keywords Imidazoleglycerol-phosphate dehydratase
molecule tags Lyase
source organism Pyrococcus furiosus
total genus 60
structure length 176
sequence length 176
chains with identical sequence B, C
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2015-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA02
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 5dnxA01
2F1DA 2AE8A 4MU3A 4QNKA 5EKWA 4GQUA 4LPFA 5DNXA 5EL9A 4MU4A 5ELWA 4MU1A 5DNLA 4LOMA 4QNJA 4MU0A 1RHYA
chains in the Genus database with same CATH superfamily
3DD6A 3HKMA 5LL6R 4DV6I 5ELWA 3HJCA 2AJ4A 1FJGI 2ZM6E 4X65E 1IBME 1XMQI 1N32I 2UXCE 2UXBE 3WU6A 1HNXI 4LFAI 5BR8I 4DV4E 3B8HA 4URLA 1S16A 3PS1A 3PS2A 2HKEA 4BA2B 3L7ZA 5IWAI 4NXNE 4JYAE 4GKKI 3U1YA 2UUAE 4IZKA 1ZM3A 3P3CA 2XEXA 2UU9E 1Z0VA 2F4VE 4OO1A 1NHHA 4LF5I 3K17A 4X66I 2UUCI 3ZKBA 2NN6F 2NN6E 4DUYI 4KHPE 2EFGA 1MX0A 3HULA 1N36I 4DR5E 1Z5CA 1XHKA 3ZZ0A 1ZM9A 4P7AA 5K36C 2HFSA 4ED4A 2PNMA 4JI3E 4JI0E 4MU1A 4X64I 4DR6E 2OI2A 4OX9E 4PU9A 4DV2E 3JAMQ 2C39A 4USKA 5LMUI 1HNWE 4HY1A 1K47A 1ZXNA 3PS3A 1S4EA 4JI1E 1J5EI 1FWLA 2O1UA 4DR4I 1KIJA 1XNRI 4LFCE 4LF7E 4LF8I 5IT9C 5A2QC 4OO1C 2BA0D 3H1CA 3F0NA 4DU8A 1Y60A 5GMEA 1IBKI 3UHMA 1PKPA 3QT6A 3J80C 2WNRA 5K36D 1E3HA 4GKJI 3QT7A 4DR3E 1R6LA 4DU7A 4JI2E 2A2DA 4B3ME 1VI7A 2VQFE 2VQEI 4DV5E 3J81Q 1I94I 4LCFA 2NN6A 2JE6B 4LF6I 4Z7CA 4K0KI 4FWGA 4B3RE 1XMOE 2PNLA 3NZKA 1ZXMA 2HHHE 2IERA 2V2QA 5DRRA 5FWKA 2UUBI 4DUZI 1HNZI 5K36F 3P76A 4OO1D 5K36E 3ZKDA 4FW4A 2PO1B 1KTVA 1NHJA 4JI8I 2CZ9A 2PO2B 1PVGA 2NPFA 2O1VA 5LMNI 2PO2A 4DR7I 3B78A 5DNLA 4LFBE 1Y5YA 1Z0TA 1Y4UA 4IS9A 4DV7E 3M6AA 1XNQI 2NN6C 3LNUA 4IFDC 4HACB 4IZJA 4LF4E 4LCGA 4NXMI 2A2CA 3KRNA 4HACA 4DPUA 3D4JA 2E5LE 1H74A 4OZEA 4AIMA 1Z0BA 4JI6I 4QNKA 3OTOE 4DR2E 1UDSA 2JEAB 4U3DA 5K36B 4LF9E 2WP8A 1FKAE 2JEAA 1FJGE 5K36A 3Q1QA 4MYUA 3L7ZB 1N32E 2LJPA 1HNXE 4LFAE 3T1HI 4IZKB 2NN6D 1Z0EA 4JI4I 5BR8E 1FWKA 3P3GA 4IFDD 4X65I 5L3JA 1IBMI 2HKJA 1KKHA 4DV1E 2R42A 4FN5A 3WU5A 5IWAE 3LTOA 1H73A 5FLXQ 4GKKE 3GCMA 4OO1B 1H7UA 1HK7A 2ZBKB 4J3DA 2DEIA 1Y6ZA 2X7IA 3PYDA 5C0XC 4U3BA 5DROA 2O1TA 4AQYI 1N34I 3CDJA 2V34A 1UDQA 4YY3I 2UUAI 4MU4A 1HR0E 1Z0CA 4DV3I 5JEAF 4B3TI 4IFDF 5JEAE 4LF5E 4IFDE 1WUUA 1FNMA 4X66E 1Z0GA 2UUCE 1D6TA 1FI4A 2V2ZA 2IOQA 1N36E 1RHYA 4DR1I 4HYMA 4GQUA 2C39B 2VF3A 2GQ0A 4IZJD 1E3PA 5C0XD 3M85G 1OJ4A 4P52A 5LMUE 4JI0I 4MQYA 3J81C 4DR6I 4OX9I 4FW7A 4DV0E 4DPWA 1J5EE 4MU3A 2JT2A 2WNRB 4HXZA 4FW6A 4FW9A 1XNRE 4LF8E 1BKNA 1N0VC 2C37A 2NN6B 1IBKE 2ZITA 2BA1G 4LFCI 4JV5E 4IFDB 5C0XF 5C0XE 4GKJE 2C38A 3J7AG 4LOMA 4ZVIA 4MDTA 5JEAA 2VQEE 4IFDA 1I94E 3K1JA 3QT5A 4LF6E 2V2VA 2IESA 1N33E 4B3MI 2VQFI 3QT8A 4B3SE 3T1YE 4N3OA 2J65A 3CWVA 4PRVA 2UUBE 4B3RI 3B4TA 2HHHI 1H72C 4MU0A 1B62A 4WUCA 5LMNE 4IZJB 2UXDI 1U2RA 2GO4A 1H7SA 5JEAC 2Z5CA 5C0XB 1XNQE 1YH8A 4M1KA 4JI7I 1NHIA 5DRPA 1USVA 3WU3A 5C0XA 1YHCA 2GS8A 1RR9A 2Z5BA 4NXME 4X62I 1EI1A 1B63A 4FW3A 4NBQA 2WP8B 2X36A 4JI5I 1MG7A 4OKGA 4DV6E 2Q2EB 3M85D 1IBLI 4YHHI 1XMQE 1Z59A 2CGEA 4FW5A 5GMDA 4USMA 4RPFA 4DPXA 5JEAD 2ZM6I 3T1HE 3V5RA 2UXBI 1R6MA 3Q6NA 2UXCI 4LF9I 5EL9A 1PIEA 1UDNA 4JI4E 3ZZTA 1N0UA 2E1RA 1DARA 2CVEA 2IOPA 2BM1A 4DV4I 2BA1D 2R3VA 4NXNI 4I3HA 4JYAI 4MYTA 3JAMC 4DV1I 3V2UC 4AQYE 1N34E 2JEBB 2AE8A 4Z7YA 5DNXA 4YY3E 3B82A 4BA2A 2JEBA 4DUYE 2UU9I 4DV3E 3GONA 4B3TE 2F4VI 3PYGA 2F1DA 4KHPI 1VISA 4DR1E 1HR0I 2HK2A 4X64E 1P42A 4DR5I 2HFUA 1Y4SA 1KVKA 3M7NG 3WU4A 3LPSA 4FWHA 1RREA 4LPFA 4PRXA 4DPTA 4JI3I 1ZM4A 2CG9A 3PYFA 4WUDA 2V8PA 3ZZUA 4DV2I 1UDOA 4DR4E 3GLLA 1OYRA 2C37B 1HNWI 4R1FA 4UT4A 1MU5A 3PYEA 2BM0A 2C38B 4JI1I 4WUBA 5JEAB 4LCHA 4LF7I 4DV0I 2HK3A 3H4LA 2O1WA 1UEKA 2BV3A 4EMDA 4KQVA 3PRYA 1Z0WA 4AIDA 3GMEA 3ZM7A 4BA1B 3J7AM 4K0KE 4DR3I 4FWDA 2PO0B 4JI2I 4DV5I 4BA1A 4JV5I 2PO0A 2J7KA 2PNZB 1A6FA 4DUZE 1HNZE 5IT9Q 3K85A 5A2QQ 1XMOI 2PNZA 4JI8E 1QZRA 1N33I 2JE6A 4DPYA 3J80Q 2WW4A 1Z5AA 4DXLA 4B3SI 3T1YI 2Z5CB 4DR7E 3CDIA 4XTJA 5DRQA 4ISAA 1OYSA 3U1KA 3P06A 3Q6MA 2UXDE 2VESA 2Z5BB 1ELOA 2GO3A 2PO1A 1USUA 4LFBI 4JI7E 2O3ZA 2Z5EA 4DV7I 3P3EA 4JG4A 4X62E 4LF4I 1XXEA 2BA0G 2BR2B 4JI6E 3M7ND 4JI5E 5FLXC 1EA6A 1NZ0A 4OO1E 4AM3A 4OO1F 2DEJA 4UTGA 1OYPA 5EKWA 2BR2A 2E5LI 1Z5BA 1IBLE 4QNJA 4YHHE 1ZM2A 4DR2I 3OTOI
chains in the Genus database with same CATH topology
2F1DA 2AE8A 4MU3A 4QNKA 5EKWA 4GQUA 4LPFA 5DNXA 5EL9A 4MU4A 5ELWA 4MU1A 5DNLA 4LOMA 4QNJA 4MU0A 1RHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1D A;  2AE8 A;  4MU3 A;  4QNK A;  5EKW A;  4GQU A;  4LPF A;  5DNX A;  5EL9 A;  4MU4 A;  5ELW A;  4MU1 A;  5DNL A;  4LOM A;  4QNJ A;  4MU0 A;  1RHY A; 
#chains in the Genus database with same CATH topology
 3DD6 A;  3HKM A;  5LL6 R;  4DV6 I;  5ELW A;  3HJC A;  2AJ4 A;  1FJG I;  2ZM6 E;  4X65 E;  1IBM E;  1XMQ I;  1N32 I;  2UXC E;  2UXB E;  3WU6 A;  1HNX I;  4LFA I;  5BR8 I;  4DV4 E;  3B8H A;  4URL A;  1S16 A;  3PS1 A;  3PS2 A;  2HKE A;  4BA2 B;  3L7Z A;  5IWA I;  4NXN E;  4JYA E;  4GKK I;  3U1Y A;  2UUA E;  4IZK A;  1ZM3 A;  3P3C A;  2XEX A;  2UU9 E;  1Z0V A;  2F4V E;  4OO1 A;  1NHH A;  4LF5 I;  3K17 A;  4X66 I;  2UUC I;  3ZKB A;  2NN6 F;  2NN6 E;  4DUY I;  4KHP E;  2EFG A;  1MX0 A;  3HUL A;  1N36 I;  4DR5 E;  1Z5C A;  1XHK A;  3ZZ0 A;  1ZM9 A;  4P7A A;  5K36 C;  2HFS A;  4ED4 A;  2PNM A;  4JI3 E;  4JI0 E;  4MU1 A;  4X64 I;  4DR6 E;  2OI2 A;  4OX9 E;  4PU9 A;  4DV2 E;  3JAM Q;  2C39 A;  4USK A;  5LMU I;  1HNW E;  4HY1 A;  1K47 A;  1ZXN A;  3PS3 A;  1S4E A;  4JI1 E;  1J5E I;  1FWL A;  2O1U A;  4DR4 I;  1KIJ A;  1XNR I;  4LFC E;  4LF7 E;  4LF8 I;  5IT9 C;  5A2Q C;  4OO1 C;  2BA0 D;  3H1C A;  3F0N A;  4DU8 A;  1Y60 A;  5GME A;  1IBK I;  3UHM A;  1PKP A;  3QT6 A;  3J80 C;  2WNR A;  5K36 D;  1E3H A;  4GKJ I;  3QT7 A;  4DR3 E;  1R6L A;  4DU7 A;  4JI2 E;  2A2D A;  4B3M E;  1VI7 A;  2VQF E;  2VQE I;  4DV5 E;  3J81 Q;  1I94 I;  4LCF A;  2NN6 A;  2JE6 B;  4LF6 I;  4Z7C A;  4K0K I;  4FWG A;  4B3R E;  1XMO E;  2PNL A;  3NZK A;  1ZXM A;  2HHH E;  2IER A;  2V2Q A;  5DRR A;  5FWK A;  2UUB I;  4DUZ I;  1HNZ I;  5K36 F;  3P76 A;  4OO1 D;  5K36 E;  3ZKD A;  4FW4 A;  2PO1 B;  1KTV A;  1NHJ A;  4JI8 I;  2CZ9 A;  2PO2 B;  1PVG A;  2NPF A;  2O1V A;  5LMN I;  2PO2 A;  4DR7 I;  3B78 A;  5DNL A;  4LFB E;  1Y5Y A;  1Z0T A;  1Y4U A;  4IS9 A;  4DV7 E;  3M6A A;  1XNQ I;  2NN6 C;  3LNU A;  4IFD C;  4HAC B;  4IZJ A;  4LF4 E;  4LCG A;  4NXM I;  2A2C A;  3KRN A;  4HAC A;  4DPU A;  3D4J A;  2E5L E;  1H74 A;  4OZE A;  4AIM A;  1Z0B A;  4JI6 I;  4QNK A;  3OTO E;  4DR2 E;  1UDS A;  2JEA B;  4U3D A;  5K36 B;  4LF9 E;  2WP8 A;  1FKA E;  2JEA A;  1FJG E;  5K36 A;  3Q1Q A;  4MYU A;  3L7Z B;  1N32 E;  2LJP A;  1HNX E;  4LFA E;  3T1H I;  4IZK B;  2NN6 D;  1Z0E A;  4JI4 I;  5BR8 E;  1FWK A;  3P3G A;  4IFD D;  4X65 I;  5L3J A;  1IBM I;  2HKJ A;  1KKH A;  4DV1 E;  2R42 A;  4FN5 A;  3WU5 A;  5IWA E;  3LTO A;  1H73 A;  5FLX Q;  4GKK E;  3GCM A;  4OO1 B;  1H7U A;  1HK7 A;  2ZBK B;  4J3D A;  2DEI A;  1Y6Z A;  2X7I A;  3PYD A;  5C0X C;  4U3B A;  5DRO A;  2O1T A;  4AQY I;  1N34 I;  3CDJ A;  2V34 A;  1UDQ A;  4YY3 I;  2UUA I;  4MU4 A;  1HR0 E;  1Z0C A;  4DV3 I;  5JEA F;  4B3T I;  4IFD F;  5JEA E;  4LF5 E;  4IFD E;  1WUU A;  1FNM A;  4X66 E;  1Z0G A;  2UUC E;  1D6T A;  1FI4 A;  2V2Z A;  2IOQ A;  1N36 E;  1RHY A;  4DR1 I;  4HYM A;  4GQU A;  2C39 B;  2VF3 A;  2GQ0 A;  4IZJ D;  1E3P A;  5C0X D;  3M85 G;  1OJ4 A;  4P52 A;  5LMU E;  4JI0 I;  4MQY A;  3J81 C;  4DR6 I;  4OX9 I;  4FW7 A;  4DV0 E;  4DPW A;  1J5E E;  4MU3 A;  2JT2 A;  2WNR B;  4HXZ A;  4FW6 A;  4FW9 A;  1XNR E;  4LF8 E;  1BKN A;  1N0V C;  2C37 A;  2NN6 B;  1IBK E;  2ZIT A;  2BA1 G;  4LFC I;  4JV5 E;  4IFD B;  5C0X F;  5C0X E;  4GKJ E;  2C38 A;  3J7A G;  4LOM A;  4ZVI A;  4MDT A;  5JEA A;  2VQE E;  4IFD A;  1I94 E;  3K1J A;  3QT5 A;  4LF6 E;  2V2V A;  2IES A;  1N33 E;  4B3M I;  2VQF I;  3QT8 A;  4B3S E;  3T1Y E;  4N3O A;  2J65 A;  3CWV A;  4PRV A;  2UUB E;  4B3R I;  3B4T A;  2HHH I;  1H72 C;  4MU0 A;  1B62 A;  4WUC A;  5LMN E;  4IZJ B;  2UXD I;  1U2R A;  2GO4 A;  1H7S A;  5JEA C;  2Z5C A;  5C0X B;  1XNQ E;  1YH8 A;  4M1K A;  4JI7 I;  1NHI A;  5DRP A;  1USV A;  3WU3 A;  5C0X A;  1YHC A;  2GS8 A;  1RR9 A;  2Z5B A;  4NXM E;  4X62 I;  1EI1 A;  1B63 A;  4FW3 A;  4NBQ A;  2WP8 B;  2X36 A;  4JI5 I;  1MG7 A;  4OKG A;  4DV6 E;  2Q2E B;  3M85 D;  1IBL I;  4YHH I;  1XMQ E;  1Z59 A;  2CGE A;  4FW5 A;  5GMD A;  4USM A;  4RPF A;  4DPX A;  5JEA D;  2ZM6 I;  3T1H E;  3V5R A;  2UXB I;  1R6M A;  3Q6N A;  2UXC I;  4LF9 I;  5EL9 A;  1PIE A;  1UDN A;  4JI4 E;  3ZZT A;  1N0U A;  2E1R A;  1DAR A;  2CVE A;  2IOP A;  2BM1 A;  4DV4 I;  2BA1 D;  2R3V A;  4NXN I;  4I3H A;  4JYA I;  4MYT A;  3JAM C;  4DV1 I;  3V2U C;  4AQY E;  1N34 E;  2JEB B;  2AE8 A;  4Z7Y A;  5DNX A;  4YY3 E;  3B82 A;  4BA2 A;  2JEB A;  4DUY E;  2UU9 I;  4DV3 E;  3GON A;  4B3T E;  2F4V I;  3PYG A;  2F1D A;  4KHP I;  1VIS A;  4DR1 E;  1HR0 I;  2HK2 A;  4X64 E;  1P42 A;  4DR5 I;  2HFU A;  1Y4S A;  1KVK A;  3M7N G;  3WU4 A;  3LPS A;  4FWH A;  1RRE A;  4LPF A;  4PRX A;  4DPT A;  4JI3 I;  1ZM4 A;  2CG9 A;  3PYF A;  4WUD A;  2V8P A;  3ZZU A;  4DV2 I;  1UDO A;  4DR4 E;  3GLL A;  1OYR A;  2C37 B;  1HNW I;  4R1F A;  4UT4 A;  1MU5 A;  3PYE A;  2BM0 A;  2C38 B;  4JI1 I;  4WUB A;  5JEA B;  4LCH A;  4LF7 I;  4DV0 I;  2HK3 A;  3H4L A;  2O1W A;  1UEK A;  2BV3 A;  4EMD A;  4KQV A;  3PRY A;  1Z0W A;  4AID A;  3GME A;  3ZM7 A;  4BA1 B;  3J7A M;  4K0K E;  4DR3 I;  4FWD A;  2PO0 B;  4JI2 I;  4DV5 I;  4BA1 A;  4JV5 I;  2PO0 A;  2J7K A;  2PNZ B;  1A6F A;  4DUZ E;  1HNZ E;  5IT9 Q;  3K85 A;  5A2Q Q;  1XMO I;  2PNZ A;  4JI8 E;  1QZR A;  1N33 I;  2JE6 A;  4DPY A;  3J80 Q;  2WW4 A;  1Z5A A;  4DXL A;  4B3S I;  3T1Y I;  2Z5C B;  4DR7 E;  3CDI A;  4XTJ A;  5DRQ A;  4ISA A;  1OYS A;  3U1K A;  3P06 A;  3Q6M A;  2UXD E;  2VES A;  2Z5B B;  1ELO A;  2GO3 A;  2PO1 A;  1USU A;  4LFB I;  4JI7 E;  2O3Z A;  2Z5E A;  4DV7 I;  3P3E A;  4JG4 A;  4X62 E;  4LF4 I;  1XXE A;  2BA0 G;  2BR2 B;  4JI6 E;  3M7N D;  4JI5 E;  5FLX C;  1EA6 A;  1NZ0 A;  4OO1 E;  4AM3 A;  4OO1 F;  2DEJ A;  4UTG A;  1OYP A;  5EKW A;  2BR2 A;  2E5L I;  1Z5B A;  1IBL E;  4QNJ A;  4YHH E;  1ZM2 A;  4DR2 I;  3OTO I; 
#chains in the Genus database with same CATH homology
 2F1D A;  2AE8 A;  4MU3 A;  4QNK A;  5EKW A;  4GQU A;  4LPF A;  5DNX A;  5EL9 A;  4MU4 A;  5ELW A;  4MU1 A;  5DNL A;  4LOM A;  4QNJ A;  4MU0 A;  1RHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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