5DROA

Structure of the aquifex aeolicus lpxc/lpc-011 complex
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Drug design from the cryptic inhibitor envelope.
pubmed doi rcsb
source organism Aquifex aeolicus (strain vf5)
molecule tags Hydrolase/hydrolase inhibitor
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2015-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 5droA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 5droA02
3P3CA 5DRQA 4LCFA 2GO3A 3P3EA 3PS3A 2GO4A 3NZKA 1YHCA 5DRRA 3UHMA 4FW4A 4U3DA 4J3DA 5DRPA 3P3GA 2J65A 3P76A 2VESA 4ISAA 2IESA 2IERA 3PS2A 4MQYA 4FW6A 4IS9A 1YH8A 1P42A 4FW5A 4LCGA 4OKGA 4OZEA 1XXEA 2JT2A 4FW3A 5DROA 4LCHA 2O3ZA 4U3BA 4FW7A 3PS1A 4MDTA 3U1YA
chains in the Genus database with same CATH superfamily
4JI4E 3M7ND 2UXBE 1IBKI 3K1JA 2C38B 1ZM9A 2XEXA 2UUCI 3HULA 4UTGA 4DV0E 4GKKI 4IZJA 2BR2A 3LTOA 1BKNA 1VI7A 2IESA 1FI4A 4MU4A 4MU0A 4B3RI 4IFDD 2JT2A 2EFGA 4B3SI 3K17A 1N34E 1UDNA 2CGEA 5IWAI 4HACA 2PO2B 4LFBI 4DUYI 4YHHI 1XNRI 4DR7E 4ZVIA 4IFDC 3H1CA 4LFAI 1S4EA 1OYPA 3HKMA 5IT9Q 4JI6E 4AIDA 1NHHA 3QT7A 5L3JA 2HKEA 2E5LE 3B78A 4JI0I 4DPTA 1MG7A 4DR6E 4OO1B 3PS2A 4QNJA 3LPSA 5IT9C 1XMOE 4FN5A 2BA1G 2HK3A 2UUAI 2HFSA 2WP8A 4IZKA 3CDIA 1DARA 2HHHE 3Q6NA 4OX9I 3J7AM 3ZZTA 2C38A 4JI5I 2IOPA 4LOMA 4WUCA 4B3TI 1RR9A 3PRYA 5LMUE 4LF9I 4IFDF 5LL6R 4DPXA 1J5EI 3ZM7A 1Z5CA 4OZEA 4DV5I 1XXEA 2VF3A 4P52A 1S16A 2WNRB 1QZRA 4LF8I 4DR2I 1N0VC 2BA0G 4MU1A 3GCMA 3PS3A 1WUUA 4JI7E 2NN6C 4IFDE 4LPFA 1OJ4A 2PO2A 1HNXE 1PKPA 1N32I 2BR2B 4OO1F 4KHPE 4XTJA 1KVKA 5FWKA 3H4LA 4DUZE 2V34A 2UU9E 4LF5E 2V8PA 1Z5AA 2F1DA 1IBKE 4PRXA 4MQYA 4LF6I 4FW6A 2JEAB 4QNKA 1B62A 5LMNI 4OO1A 4N3OA 4HACB 4JI8I 4GKKE 2Z5EA 5BR8E 3U1YA 3T1HE 3M85G 2CG9A 1Y5YA 3D4JA 4MYUA 3HJCA 5LMUI 4B3SE 1YHCA 5DRRA 4DR3I 2OI2A 4NXNI 3J80Q 5DRPA 2PNZB 3ZKBA 3P76A 4DUYE 4LFBE 1E3PA 4YHHE 1XNRE 3P06A 4HY1A 4DV7I 2F4VI 4ED4A 3M7NG 1OYRA 3J80C 1Z0VA 2GS8A 3U1KA 2GQ0A 3WU6A 2O3ZA 4WUDA 4U3BA 4FW7A 4JI0E 1NZ0A 5EKWA 3B82A 1N0UA 2A2CA 2WNRA 4DR5I 1Z0TA 4FWHA 2UUAE 2J65A 4JG4A 3PYEA 5BR8I 1Z0WA 3T1HI 2X36A 2Q2EB 2PNMA 4OX9E 1Y4UA 5C0XC 4DR4I 4JI5E 2JE6B 2DEIA 4LF5I 2DEJA 4X62E 1Z59A 4B3TE 2JEAA 4JI2E 4URLA 4IFDB 4LF9E 4FWGA 1J5EE 3QT8A 1NHJA 4DV5E 4JI1I 3CWVA 1Z5BA 3V2UC 1ZM4A 4DV4I 4RPFA 4LF8E 4DR2E 4K0KI 3GLLA 1R6MA 1N33I 2IERA 4R1FA 1PIEA 4LCGA 2PNZA 4FW5A 5ELWA 1N32E 2C37B 3Q1QA 2NPFA 1OYSA 4LCHA 4DR1I 5DNXA 3F0NA 4OKGA 1KTVA 4LF6E 1D6TA 5A2QQ 1UDOA 3J7AG 2O1WA 4X66I 4BA2B 5K36D 2GO4A 5LMNE 4JI8E 3NZKA 4YY3I 5A2QC 4X62I 4P7AA 5K36C 4JI2I 1P42A 2E1RA 5EL9A 3OTOI 1FKAE 1ZXNA 1Z0CA 4FW3A 4DR3E 3M6AA 4NXNE 2NN6D 1E3HA 3QT6A 4EMDA 3LNUA 4LFCI 2JE6A 3KRNA 4DV7E 2AJ4A 2NN6B 2F4VE 2R3VA 4WUBA 1IBLI 4IFDA 2HK2A 4X64I 4X65E 1HR0I 2CVEA 4AQYI 3PYGA 4PU9A 5GMDA 1XMQI 1UEKA 3K85A 4JV5E 1H7UA 4DR5E 2ZBKB 3L7ZB 4AM3A 5JEAD 1PVGA 2A2DA 2C37A 4DV2I 5JEAC 2GO3A 3P3EA 1UDSA 1XNQI 1FNMA 1EA6A 1Z0GA 4M1KA 4DR4E 4BA2A 3QT5A 1HNWI 2LJPA 3ZZ0A 4MU3A 4DV1I 2VESA 5K36E 4DPWA 4JI3I 2NN6F 4JI1E 4DV6I 1H7SA 2HFUA 4X65I 4DV4E 4GKJI 1XHKA 4K0KE 3V5RA 1FWKA 3P3CA 1N33E 2CZ9A 1KKHA 4JV5I 3Q6MA 4LF4E 1ZM3A 2NN6E 2NN6A 2C39B 2JEBB 2ZM6I 4BA1B 4DR1E 4FW4A 1ZXMA 1H72C 4I3HA 2UUBI 5C0XD 4FWDA 2BM1A 5JEAF 2J7KA 3CDJA 4ISAA 2Z5BB 2O1TA 2IOQA 4DPUA 4X66E 5C0XB 4JYAE 1FJGE 1RREA 2VQEI 3PYDA 2R42A 4YY3E 2V2ZA 3WU5A 3L7ZA 1A6FA 3PS1A 4USKA 5JEAE 5JEAA 4DV3I 1MU5A 1Z0BA 3ZZUA 3OTOE 1B63A 4NXMI 3UHMA 4U3DA 4J3DA 1RHYA 3P3GA 1Y60A 4AIMA 3T1YI 4LFCE 2V2VA 2PO1B 2VQFI 1IBLE 4X64E 3GONA 2AE8A 3B4TA 1HR0E 4LF4I 1K47A 4NBQA 2PO0A 5FLXQ 4AQYE 4FW9A 1HNZI 3ZKDA 1XMQE 3PYFA 1H74A 5DRQA 4DU7A 1USUA 4DU8A 5FLXC 2WW4A 1ELOA 4JYAI 5C0XF 1FJGI 1R6LA 1MX0A 4DV2E 4OO1D 5K36B 4LF7E 2C39A 2JEBA 4BA1A 4JI4I 1XNQE 2UXBI 4Z7YA 4IS9A 4OO1C 5C0XE 2Z5BA 5C0XA 3JAMQ 1N36I 4DV0I 1HNWE 4PRVA 4DV1E 2X7IA 1EI1A 4UT4A 2V2QA 2PNLA 2O1UA 4JI3E 1KIJA 2BA1D 3JAMC 3B8HA 1I94E 2ZITA 4DV6E 4GKJE 3WU3A 4Z7CA 2HKJA 1N34I 2UXCE 1Y4SA 2UXDE 1VISA 4DR7I 1IBME 2Z5CB 2PO1A 2ZM6E 5DROA 4JI6I 2UUBE 5JEAB 2E5LI 4IZJD 4HXZA 4LF7I 5K36F 4USMA 4DR6I 4IZJB 2VQEE 4MYTA 1XMOI 4GQUA 4HYMA 4B3ME 1N36E 4DPYA 1UDQA 4KQVA 2BA0D 4DV3E 1U2RA 5K36A 1YH8A 3J81Q 2UUCE 2HHHI 4NXME 2PO0B 4OO1E 1I94I 4DXLA 1USVA 1H73A 5DNLA 3T1YE 2O1VA 3DD6A 3J81C 2VQFE 4LCFA 2UXCI 5GMEA 2UXDI 4B3RE 1IBMI 1Y6ZA 3WU4A 5IWAE 1HNZE 3M85D 1FWLA 1NHIA 3GMEA 4LFAE 2BM0A 1ZM2A 1HK7A 4JI7I 2BV3A 1HNXI 2WP8B 4IZKB 4KHPI 1Z0EA 4B3MI 2Z5CA 4DUZI 4MDTA 2UU9I
chains in the Genus database with same CATH topology
3P3CA 5DRQA 4LCFA 2GO3A 3P3EA 3PS3A 2GO4A 3NZKA 1YHCA 5DRRA 3UHMA 4FW4A 4U3DA 4J3DA 5DRPA 3P3GA 2J65A 3P76A 2VESA 4ISAA 2IESA 2IERA 3PS2A 4MQYA 4FW6A 4IS9A 1YH8A 1P42A 4FW5A 4LCGA 4OKGA 4OZEA 1XXEA 2JT2A 4FW3A 5DROA 4LCHA 2O3ZA 4U3BA 4FW7A 3PS1A 4MDTA 3U1YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P3C A;  5DRQ A;  4LCF A;  2GO3 A;  3P3E A;  3PS3 A;  2GO4 A;  3NZK A;  1YHC A;  5DRR A;  3UHM A;  4FW4 A;  4U3D A;  4J3D A;  5DRP A;  3P3G A;  2J65 A;  3P76 A;  2VES A;  4ISA A;  2IES A;  2IER A;  3PS2 A;  4MQY A;  4FW6 A;  4IS9 A;  1YH8 A;  1P42 A;  4FW5 A;  4LCG A;  4OKG A;  4OZE A;  1XXE A;  2JT2 A;  4FW3 A;  5DRO A;  4LCH A;  2O3Z A;  4U3B A;  4FW7 A;  3PS1 A;  4MDT A;  3U1Y A; 
#chains in the Genus database with same CATH topology
 4JI4 E;  3M7N D;  2UXB E;  1IBK I;  3K1J A;  2C38 B;  1ZM9 A;  2XEX A;  2UUC I;  3HUL A;  4UTG A;  4DV0 E;  4GKK I;  4IZJ A;  2BR2 A;  3LTO A;  1BKN A;  1VI7 A;  2IES A;  1FI4 A;  4MU4 A;  4MU0 A;  4B3R I;  4IFD D;  2JT2 A;  2EFG A;  4B3S I;  3K17 A;  1N34 E;  1UDN A;  2CGE A;  5IWA I;  4HAC A;  2PO2 B;  4LFB I;  4DUY I;  4YHH I;  1XNR I;  4DR7 E;  4ZVI A;  4IFD C;  3H1C A;  4LFA I;  1S4E A;  1OYP A;  3HKM A;  5IT9 Q;  4JI6 E;  4AID A;  1NHH A;  3QT7 A;  5L3J A;  2HKE A;  2E5L E;  3B78 A;  4JI0 I;  4DPT A;  1MG7 A;  4DR6 E;  4OO1 B;  3PS2 A;  4QNJ A;  3LPS A;  5IT9 C;  1XMO E;  4FN5 A;  2BA1 G;  2HK3 A;  2UUA I;  2HFS A;  2WP8 A;  4IZK A;  3CDI A;  1DAR A;  2HHH E;  3Q6N A;  4OX9 I;  3J7A M;  3ZZT A;  2C38 A;  4JI5 I;  2IOP A;  4LOM A;  4WUC A;  4B3T I;  1RR9 A;  3PRY A;  5LMU E;  4LF9 I;  4IFD F;  5LL6 R;  4DPX A;  1J5E I;  3ZM7 A;  1Z5C A;  4OZE A;  4DV5 I;  1XXE A;  2VF3 A;  4P52 A;  1S16 A;  2WNR B;  1QZR A;  4LF8 I;  4DR2 I;  1N0V C;  2BA0 G;  4MU1 A;  3GCM A;  3PS3 A;  1WUU A;  4JI7 E;  2NN6 C;  4IFD E;  4LPF A;  1OJ4 A;  2PO2 A;  1HNX E;  1PKP A;  1N32 I;  2BR2 B;  4OO1 F;  4KHP E;  4XTJ A;  1KVK A;  5FWK A;  3H4L A;  4DUZ E;  2V34 A;  2UU9 E;  4LF5 E;  2V8P A;  1Z5A A;  2F1D A;  1IBK E;  4PRX A;  4MQY A;  4LF6 I;  4FW6 A;  2JEA B;  4QNK A;  1B62 A;  5LMN I;  4OO1 A;  4N3O A;  4HAC B;  4JI8 I;  4GKK E;  2Z5E A;  5BR8 E;  3U1Y A;  3T1H E;  3M85 G;  2CG9 A;  1Y5Y A;  3D4J A;  4MYU A;  3HJC A;  5LMU I;  4B3S E;  1YHC A;  5DRR A;  4DR3 I;  2OI2 A;  4NXN I;  3J80 Q;  5DRP A;  2PNZ B;  3ZKB A;  3P76 A;  4DUY E;  4LFB E;  1E3P A;  4YHH E;  1XNR E;  3P06 A;  4HY1 A;  4DV7 I;  2F4V I;  4ED4 A;  3M7N G;  1OYR A;  3J80 C;  1Z0V A;  2GS8 A;  3U1K A;  2GQ0 A;  3WU6 A;  2O3Z A;  4WUD A;  4U3B A;  4FW7 A;  4JI0 E;  1NZ0 A;  5EKW A;  3B82 A;  1N0U A;  2A2C A;  2WNR A;  4DR5 I;  1Z0T A;  4FWH A;  2UUA E;  2J65 A;  4JG4 A;  3PYE A;  5BR8 I;  1Z0W A;  3T1H I;  2X36 A;  2Q2E B;  2PNM A;  4OX9 E;  1Y4U A;  5C0X C;  4DR4 I;  4JI5 E;  2JE6 B;  2DEI A;  4LF5 I;  2DEJ A;  4X62 E;  1Z59 A;  4B3T E;  2JEA A;  4JI2 E;  4URL A;  4IFD B;  4LF9 E;  4FWG A;  1J5E E;  3QT8 A;  1NHJ A;  4DV5 E;  4JI1 I;  3CWV A;  1Z5B A;  3V2U C;  1ZM4 A;  4DV4 I;  4RPF A;  4LF8 E;  4DR2 E;  4K0K I;  3GLL A;  1R6M A;  1N33 I;  2IER A;  4R1F A;  1PIE A;  4LCG A;  2PNZ A;  4FW5 A;  5ELW A;  1N32 E;  2C37 B;  3Q1Q A;  2NPF A;  1OYS A;  4LCH A;  4DR1 I;  5DNX A;  3F0N A;  4OKG A;  1KTV A;  4LF6 E;  1D6T A;  5A2Q Q;  1UDO A;  3J7A G;  2O1W A;  4X66 I;  4BA2 B;  5K36 D;  2GO4 A;  5LMN E;  4JI8 E;  3NZK A;  4YY3 I;  5A2Q C;  4X62 I;  4P7A A;  5K36 C;  4JI2 I;  1P42 A;  2E1R A;  5EL9 A;  3OTO I;  1FKA E;  1ZXN A;  1Z0C A;  4FW3 A;  4DR3 E;  3M6A A;  4NXN E;  2NN6 D;  1E3H A;  3QT6 A;  4EMD A;  3LNU A;  4LFC I;  2JE6 A;  3KRN A;  4DV7 E;  2AJ4 A;  2NN6 B;  2F4V E;  2R3V A;  4WUB A;  1IBL I;  4IFD A;  2HK2 A;  4X64 I;  4X65 E;  1HR0 I;  2CVE A;  4AQY I;  3PYG A;  4PU9 A;  5GMD A;  1XMQ I;  1UEK A;  3K85 A;  4JV5 E;  1H7U A;  4DR5 E;  2ZBK B;  3L7Z B;  4AM3 A;  5JEA D;  1PVG A;  2A2D A;  2C37 A;  4DV2 I;  5JEA C;  2GO3 A;  3P3E A;  1UDS A;  1XNQ I;  1FNM A;  1EA6 A;  1Z0G A;  4M1K A;  4DR4 E;  4BA2 A;  3QT5 A;  1HNW I;  2LJP A;  3ZZ0 A;  4MU3 A;  4DV1 I;  2VES A;  5K36 E;  4DPW A;  4JI3 I;  2NN6 F;  4JI1 E;  4DV6 I;  1H7S A;  2HFU A;  4X65 I;  4DV4 E;  4GKJ I;  1XHK A;  4K0K E;  3V5R A;  1FWK A;  3P3C A;  1N33 E;  2CZ9 A;  1KKH A;  4JV5 I;  3Q6M A;  4LF4 E;  1ZM3 A;  2NN6 E;  2NN6 A;  2C39 B;  2JEB B;  2ZM6 I;  4BA1 B;  4DR1 E;  4FW4 A;  1ZXM A;  1H72 C;  4I3H A;  2UUB I;  5C0X D;  4FWD A;  2BM1 A;  5JEA F;  2J7K A;  3CDJ A;  4ISA A;  2Z5B B;  2O1T A;  2IOQ A;  4DPU A;  4X66 E;  5C0X B;  4JYA E;  1FJG E;  1RRE A;  2VQE I;  3PYD A;  2R42 A;  4YY3 E;  2V2Z A;  3WU5 A;  3L7Z A;  1A6F A;  3PS1 A;  4USK A;  5JEA E;  5JEA A;  4DV3 I;  1MU5 A;  1Z0B A;  3ZZU A;  3OTO E;  1B63 A;  4NXM I;  3UHM A;  4U3D A;  4J3D A;  1RHY A;  3P3G A;  1Y60 A;  4AIM A;  3T1Y I;  4LFC E;  2V2V A;  2PO1 B;  2VQF I;  1IBL E;  4X64 E;  3GON A;  2AE8 A;  3B4T A;  1HR0 E;  4LF4 I;  1K47 A;  4NBQ A;  2PO0 A;  5FLX Q;  4AQY E;  4FW9 A;  1HNZ I;  3ZKD A;  1XMQ E;  3PYF A;  1H74 A;  5DRQ A;  4DU7 A;  1USU A;  4DU8 A;  5FLX C;  2WW4 A;  1ELO A;  4JYA I;  5C0X F;  1FJG I;  1R6L A;  1MX0 A;  4DV2 E;  4OO1 D;  5K36 B;  4LF7 E;  2C39 A;  2JEB A;  4BA1 A;  4JI4 I;  1XNQ E;  2UXB I;  4Z7Y A;  4IS9 A;  4OO1 C;  5C0X E;  2Z5B A;  5C0X A;  3JAM Q;  1N36 I;  4DV0 I;  1HNW E;  4PRV A;  4DV1 E;  2X7I A;  1EI1 A;  4UT4 A;  2V2Q A;  2PNL A;  2O1U A;  4JI3 E;  1KIJ A;  2BA1 D;  3JAM C;  3B8H A;  1I94 E;  2ZIT A;  4DV6 E;  4GKJ E;  3WU3 A;  4Z7C A;  2HKJ A;  1N34 I;  2UXC E;  1Y4S A;  2UXD E;  1VIS A;  4DR7 I;  1IBM E;  2Z5C B;  2PO1 A;  2ZM6 E;  5DRO A;  4JI6 I;  2UUB E;  5JEA B;  2E5L I;  4IZJ D;  4HXZ A;  4LF7 I;  5K36 F;  4USM A;  4DR6 I;  4IZJ B;  2VQE E;  4MYT A;  1XMO I;  4GQU A;  4HYM A;  4B3M E;  1N36 E;  4DPY A;  1UDQ A;  4KQV A;  2BA0 D;  4DV3 E;  1U2R A;  5K36 A;  1YH8 A;  3J81 Q;  2UUC E;  2HHH I;  4NXM E;  2PO0 B;  4OO1 E;  1I94 I;  4DXL A;  1USV A;  1H73 A;  5DNL A;  3T1Y E;  2O1V A;  3DD6 A;  3J81 C;  2VQF E;  4LCF A;  2UXC I;  5GME A;  2UXD I;  4B3R E;  1IBM I;  1Y6Z A;  3WU4 A;  5IWA E;  1HNZ E;  3M85 D;  1FWL A;  1NHI A;  3GME A;  4LFA E;  2BM0 A;  1ZM2 A;  1HK7 A;  4JI7 I;  2BV3 A;  1HNX I;  2WP8 B;  4IZK B;  4KHP I;  1Z0E A;  4B3M I;  2Z5C A;  4DUZ I;  4MDT A;  2UU9 I; 
#chains in the Genus database with same CATH homology
 3P3C A;  5DRQ A;  4LCF A;  2GO3 A;  3P3E A;  3PS3 A;  2GO4 A;  3NZK A;  1YHC A;  5DRR A;  3UHM A;  4FW4 A;  4U3D A;  4J3D A;  5DRP A;  3P3G A;  2J65 A;  3P76 A;  2VES A;  4ISA A;  2IES A;  2IER A;  3PS2 A;  4MQY A;  4FW6 A;  4IS9 A;  1YH8 A;  1P42 A;  4FW5 A;  4LCG A;  4OKG A;  4OZE A;  1XXE A;  2JT2 A;  4FW3 A;  5DRO A;  4LCH A;  2O3Z A;  4U3B A;  4FW7 A;  3PS1 A;  4MDT A;  3U1Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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