5DUAA

First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 3a
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
446
structure length
445
Chain Sequence
NSSVRHGLTSAQHCVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDRPEPVSLTGGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords CDA peptide synthetase I
publication title Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
source organism Streptomyces coelicolor (strain atcc baa-471 / a3(2) / m145)
molecule tags Phosphopantetheine binding protein
total genus 139
structure length 445
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 5duaA01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 5duaA02
2II5A 4KE4A 3FP0A 5FALA 2ZBAA 5KJTA 5KJSA 1XL7A 2BGHA 1NOCB 5DU9A 5FANA 4HVMA 1CIAA 2IHWA 2XHGA 2XR7A 5KJWA 1XMCA 1EACA 3U9FA 4CLAA 1Q9JA 2E1TA 5KJVA 1E2OA 3CLAA 2RKVA 4JN3A 1DPCA 2E1VA 2RKTA 2E1UA 1DPDA 1XMDA 4G22A 1XL8A 4KECA 3U9BA 2II4A 4G0BA 1DPBA 5T3EA 1QCAA 1L5AA 3B30A 2CLAA 2I9DA 3B2SA 1EADA 4G2MA 1Q23A 1CLAA 1C4TA 1EAAA 3L60A 1EABA 4JN5A 4N72A 1EAEA 2II3A 1SCZA 5DUAA 3FOTA 3MAEA 1PD5A 1EAFA 5KJUA 2VSQA 2JGPA
chains in the Genus database with same CATH superfamily
2FW3A 4KE4A 5FALA 5KJTA 5KJWA 1CIAA 2H3UA 1Q9JA 2FY3A 2RKVA 5T3EA 1DPBA 4EYWA 1QCAA 1L5AA 3B30A 1Q23A 1CLAA 4JN5A 2H4TA 1EABA 1T7OA 1NDFA 2H3PA 2FY5A 1SCZA 5KJUA 4EPHA 2II5A 5DU9A 2XHGA 1NDIA 2XR7A 1EACA 2H3WA 3U9FA 2DEBA 1DPCA 2E1VA 2RKTA 1XMDA 2II4A 2CLAA 4G2MA 2FY4A 1T7NA 2II3A 3FOTA 1PD5A 5KJSA 1XL7A 4HVMA 2IHWA 1NDBA 1XMCA 2E1TA 5KJVA 4JN3A 4EP9A 1Q6XA 1XL8A 3U9BA 2FY2A 3B2SA 1EADA 4N72A 1C4TA 1EAAA 1EAEA 5DUAA 1NM8A 2VSQA 2JGPA 2RCUA 3FP0A 2FYOA 1S5OA 2ZBAA 2BGHA 1NOCB 5FANA 4CLAA 1E2OA 3CLAA 2E1UA 1DPDA 4G22A 4KECA 4G0BA 1T7QA 2I9DA 3L60A 3MAEA 1EAFA 1T1UA
chains in the Genus database with same CATH topology
2FW3A 4KE4A 5FALA 5KJTA 5KJWA 1CIAA 2H3UA 1Q9JA 2FY3A 2RKVA 5T3EA 1DPBA 4EYWA 1QCAA 1L5AA 3B30A 1Q23A 1CLAA 4JN5A 2H4TA 1EABA 1T7OA 1NDFA 2H3PA 2FY5A 1SCZA 5KJUA 4EPHA 2II5A 5DU9A 2XHGA 1NDIA 2XR7A 1EACA 3U9FA 2H3WA 2DEBA 1DPCA 2E1VA 2RKTA 1XMDA 2II4A 2CLAA 4G2MA 2FY4A 1T7NA 2II3A 3FOTA 1PD5A 5KJSA 1XL7A 4HVMA 2IHWA 1NDBA 1XMCA 2E1TA 5KJVA 4JN3A 4EP9A 1Q6XA 1XL8A 3U9BA 2FY2A 3B2SA 1EADA 4N72A 1C4TA 1EAAA 1EAEA 5DUAA 1NM8A 2VSQA 2JGPA 2RCUA 3FP0A 2FYOA 2ZBAA 1S5OA 2BGHA 1NOCB 5FANA 4CLAA 1E2OA 3CLAA 2E1UA 1DPDA 4G22A 4KECA 4G0BA 1T7QA 2I9DA 3L60A 3MAEA 1EAFA 1T1UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2II5 A;  4KE4 A;  3FP0 A;  5FAL A;  2ZBA A;  5KJT A;  5KJS A;  1XL7 A;  2BGH A;  1NOC B;  5DU9 A;  5FAN A;  4HVM A;  1CIA A;  2IHW A;  2XHG A;  2XR7 A;  5KJW A;  1XMC A;  1EAC A;  3U9F A;  4CLA A;  1Q9J A;  2E1T A;  5KJV A;  1E2O A;  3CLA A;  2RKV A;  4JN3 A;  1DPC A;  2E1V A;  2RKT A;  2E1U A;  1DPD A;  1XMD A;  4G22 A;  1XL8 A;  4KEC A;  3U9B A;  2II4 A;  4G0B A;  1DPB A;  5T3E A;  1QCA A;  1L5A A;  3B30 A;  2CLA A;  2I9D A;  3B2S A;  1EAD A;  4G2M A;  1Q23 A;  1CLA A;  1C4T A;  1EAA A;  3L60 A;  1EAB A;  4JN5 A;  4N72 A;  1EAE A;  2II3 A;  1SCZ A;  5DUA A;  3FOT A;  3MAE A;  1PD5 A;  1EAF A;  5KJU A;  2VSQ A;  2JGP A; 
#chains in the Genus database with same CATH topology
 2FW3 A;  4KE4 A;  5FAL A;  5KJT A;  5KJW A;  1CIA A;  2H3U A;  1Q9J A;  2FY3 A;  2RKV A;  5T3E A;  1DPB A;  4EYW A;  1QCA A;  1L5A A;  3B30 A;  1Q23 A;  1CLA A;  4JN5 A;  2H4T A;  1EAB A;  1T7O A;  1NDF A;  2H3P A;  2FY5 A;  1SCZ A;  5KJU A;  4EPH A;  2II5 A;  5DU9 A;  2XHG A;  1NDI A;  2XR7 A;  1EAC A;  2H3W A;  3U9F A;  2DEB A;  1DPC A;  2E1V A;  2RKT A;  1XMD A;  2II4 A;  2CLA A;  4G2M A;  2FY4 A;  1T7N A;  2II3 A;  3FOT A;  1PD5 A;  5KJS A;  1XL7 A;  4HVM A;  2IHW A;  1NDB A;  1XMC A;  2E1T A;  5KJV A;  4JN3 A;  4EP9 A;  1Q6X A;  1XL8 A;  3U9B A;  2FY2 A;  3B2S A;  1EAD A;  4N72 A;  1C4T A;  1EAA A;  1EAE A;  5DUA A;  1NM8 A;  2VSQ A;  2JGP A;  2RCU A;  3FP0 A;  2FYO A;  1S5O A;  2ZBA A;  2BGH A;  1NOC B;  5FAN A;  4CLA A;  1E2O A;  3CLA A;  2E1U A;  1DPD A;  4G22 A;  4KEC A;  4G0B A;  1T7Q A;  2I9D A;  3L60 A;  3MAE A;  1EAF A;  1T1U A; 
#chains in the Genus database with same CATH homology
 2FW3 A;  4KE4 A;  5FAL A;  5KJT A;  5KJW A;  1CIA A;  2H3U A;  1Q9J A;  2FY3 A;  2RKV A;  5T3E A;  1DPB A;  4EYW A;  1QCA A;  1L5A A;  3B30 A;  1Q23 A;  1CLA A;  4JN5 A;  2H4T A;  1EAB A;  1T7O A;  1NDF A;  2H3P A;  2FY5 A;  1SCZ A;  5KJU A;  4EPH A;  2II5 A;  5DU9 A;  2XHG A;  1NDI A;  2XR7 A;  1EAC A;  3U9F A;  2H3W A;  2DEB A;  1DPC A;  2E1V A;  2RKT A;  1XMD A;  2II4 A;  2CLA A;  4G2M A;  2FY4 A;  1T7N A;  2II3 A;  3FOT A;  1PD5 A;  5KJS A;  1XL7 A;  4HVM A;  2IHW A;  1NDB A;  1XMC A;  2E1T A;  5KJV A;  4JN3 A;  4EP9 A;  1Q6X A;  1XL8 A;  3U9B A;  2FY2 A;  3B2S A;  1EAD A;  4N72 A;  1C4T A;  1EAA A;  1EAE A;  5DUA A;  1NM8 A;  2VSQ A;  2JGP A;  2RCU A;  3FP0 A;  2FYO A;  2ZBA A;  1S5O A;  2BGH A;  1NOC B;  5FAN A;  4CLA A;  1E2O A;  3CLA A;  2E1U A;  1DPD A;  4G22 A;  4KEC A;  4G0B A;  1T7Q A;  2I9D A;  3L60 A;  3MAE A;  1EAF A;  1T1U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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