5DUAA

First condensation domain of the calcium-dependent antibiotic synthetase in complex with substrate analogue 3a
Total Genus 139
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
446
structure length
445
Chain Sequence
NSSVRHGLTSAQHCVWLAQQLDPRGAHYRTGSCLEIDGPLDHAVLSRALRLTVAGTETLCSRFLTDEEGRPYRAYCPPAPEGSAAVEDPDGVPYTPVLLRHIDLSGHEDPEGEAQRWMDRDRATPLPLDRPGLSSHALFTLGGGRHLYYLGVHHIVIDGTSMALFYERLAEVYRALRDGRAVPAAAFGDTDRMVAGEEAYRASARYERDRAYWTGLFTDRPEPVSLTGGGGRALAPTVRSLGLPPERTEVLGRAAEATGAHWARVVIAGVAAFLHRTTGARDVVVSVPVTGRYGANARITPGMVSNRLPLRLAVRPGESFARVVETVSEAMSGLLAHSRFRGEDLDRELGGAGVSGPTVNVMPYIRPVDFGGPVGLMRSISSGPTTDLNIVLTGTPESGLRVDFEGNPQVYGGQDLTVLQERFVRFLAELAADPAATVDEVALLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases.
pubmed doi rcsb
molecule tags Phosphopantetheine binding protein
source organism Streptomyces coelicolor (strain atcc baa-471 / a3(2) / m145)
molecule keywords CDA peptide synthetase I
total genus 139
structure length 445
sequence length 446
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-09-18
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.559.10 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol acetyltransferase-like domain 5duaA01
3.30.559.30 Alpha Beta 2-Layer Sandwich Chloramphenicol Acetyltransferase Chloramphenicol Acetyltransferase 5duaA02
2II3A 2RKVA 1DPCA 2II4A 1C4TA 4JN5A 1CIAA 4G22A 5KJUA 1EAAA 1EADA 3FOTA 1L5AA 2VSQA 1XL7A 4N72A 2E1VA 2RKTA 3U9FA 2II5A 1E2OA 2XHGA 2E1TA 1DPDA 2ZBAA 3L60A 5DUAA 3U9BA 1EABA 5FALA 4CLAA 1QCAA 3B30A 2JGPA 4JN3A 5KJTA 2E1UA 2IHWA 3MAEA 1CLAA 1Q23A 2I9DA 4G0BA 4KE4A 5FANA 4G2MA 1NOCB 4KECA 1DPBA 1EACA 1EAFA 3B2SA 5DU9A 1PD5A 2CLAA 1Q9JA 1XL8A 3CLAA 1EAEA 3FP0A 1XMCA 5T3EA 1XMDA 2XR7A 2BGHA 4HVMA 5KJSA 1SCZA 5KJVA 5KJWA
chains in the Genus database with same CATH superfamily
2RKVA 2FY2A 4JN5A 1CIAA 2FY5A 2H3UA 1EAAA 1L5AA 3FOTA 2II5A 5FALA 1EABA 2IHWA 1CLAA 2FYOA 4G2MA 1NOCB 5T3EA 4EPHA 5KJSA 1T7QA 2BGHA 2H4TA 2DEBA 1T7NA 5KJWA 2II3A 1NDBA 5KJUA 1XL7A 2E1VA 2FY4A 1E2OA 1DPDA 4JN3A 5KJTA 2E1UA 1T7OA 4G0BA 1T1UA 4KECA 1PD5A 1Q9JA 1XL8A 2FW3A 1NM8A 3FP0A 1XMDA 4EYWA 4HVMA 1SCZA 5KJVA 1DPCA 2II4A 4EP9A 3U9FA 2E1TA 1NDFA 2ZBAA 3L60A 5DUAA 3B30A 2JGPA 2I9DA 2FY3A 1DPBA 5DU9A 2CLAA 2RCUA 3CLAA 1EAEA 1XMCA 1S5OA 1C4TA 4G22A 1EADA 2H3WA 2VSQA 4N72A 2RKTA 2XHGA 3U9BA 4CLAA 1QCAA 3MAEA 1Q23A 1Q6XA 4KE4A 5FANA 1EACA 1EAFA 3B2SA 1NDIA 2H3PA 2XR7A
chains in the Genus database with same CATH topology
2RKVA 2FY2A 4JN5A 1CIAA 2FY5A 2H3UA 1EAAA 1L5AA 3FOTA 2II5A 5FALA 1EABA 2IHWA 1CLAA 2FYOA 4G2MA 1NOCB 5T3EA 4EPHA 5KJSA 2BGHA 1T7QA 2DEBA 1T7NA 2H4TA 5KJWA 2II3A 1NDBA 5KJUA 1XL7A 2E1VA 2FY4A 1E2OA 1DPDA 4JN3A 5KJTA 2E1UA 1T7OA 4G0BA 1T1UA 4KECA 1PD5A 1Q9JA 1XL8A 2FW3A 3FP0A 1NM8A 1XMDA 4EYWA 4HVMA 1SCZA 5KJVA 1DPCA 2II4A 4EP9A 3U9FA 2E1TA 2ZBAA 3L60A 5DUAA 1NDFA 3B30A 2JGPA 2I9DA 2FY3A 1DPBA 5DU9A 2CLAA 2RCUA 3CLAA 1EAEA 1XMCA 1S5OA 1C4TA 4G22A 1EADA 2H3WA 2VSQA 4N72A 2RKTA 2XHGA 3U9BA 4CLAA 1QCAA 3MAEA 1Q23A 4KE4A 5FANA 1Q6XA 1EACA 1EAFA 3B2SA 1NDIA 2H3PA 2XR7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2II3 A;  2RKV A;  1DPC A;  2II4 A;  1C4T A;  4JN5 A;  1CIA A;  4G22 A;  5KJU A;  1EAA A;  1EAD A;  3FOT A;  1L5A A;  2VSQ A;  1XL7 A;  4N72 A;  2E1V A;  2RKT A;  3U9F A;  2II5 A;  1E2O A;  2XHG A;  2E1T A;  1DPD A;  2ZBA A;  3L60 A;  5DUA A;  3U9B A;  1EAB A;  5FAL A;  4CLA A;  1QCA A;  3B30 A;  2JGP A;  4JN3 A;  5KJT A;  2E1U A;  2IHW A;  3MAE A;  1CLA A;  1Q23 A;  2I9D A;  4G0B A;  4KE4 A;  5FAN A;  4G2M A;  1NOC B;  4KEC A;  1DPB A;  1EAC A;  1EAF A;  3B2S A;  5DU9 A;  1PD5 A;  2CLA A;  1Q9J A;  1XL8 A;  3CLA A;  1EAE A;  3FP0 A;  1XMC A;  5T3E A;  1XMD A;  2XR7 A;  2BGH A;  4HVM A;  5KJS A;  1SCZ A;  5KJV A;  5KJW A; 
#chains in the Genus database with same CATH topology
 2RKV A;  2FY2 A;  4JN5 A;  1CIA A;  2FY5 A;  2H3U A;  1EAA A;  1L5A A;  3FOT A;  2II5 A;  5FAL A;  1EAB A;  2IHW A;  1CLA A;  2FYO A;  4G2M A;  1NOC B;  5T3E A;  4EPH A;  5KJS A;  1T7Q A;  2BGH A;  2H4T A;  2DEB A;  1T7N A;  5KJW A;  2II3 A;  1NDB A;  5KJU A;  1XL7 A;  2E1V A;  2FY4 A;  1E2O A;  1DPD A;  4JN3 A;  5KJT A;  2E1U A;  1T7O A;  4G0B A;  1T1U A;  4KEC A;  1PD5 A;  1Q9J A;  1XL8 A;  2FW3 A;  1NM8 A;  3FP0 A;  1XMD A;  4EYW A;  4HVM A;  1SCZ A;  5KJV A;  1DPC A;  2II4 A;  4EP9 A;  3U9F A;  2E1T A;  1NDF A;  2ZBA A;  3L60 A;  5DUA A;  3B30 A;  2JGP A;  2I9D A;  2FY3 A;  1DPB A;  5DU9 A;  2CLA A;  2RCU A;  3CLA A;  1EAE A;  1XMC A;  1S5O A;  1C4T A;  4G22 A;  1EAD A;  2H3W A;  2VSQ A;  4N72 A;  2RKT A;  2XHG A;  3U9B A;  4CLA A;  1QCA A;  3MAE A;  1Q23 A;  1Q6X A;  4KE4 A;  5FAN A;  1EAC A;  1EAF A;  3B2S A;  1NDI A;  2H3P A;  2XR7 A; 
#chains in the Genus database with same CATH homology
 2RKV A;  2FY2 A;  4JN5 A;  1CIA A;  2FY5 A;  2H3U A;  1EAA A;  1L5A A;  3FOT A;  2II5 A;  5FAL A;  1EAB A;  2IHW A;  1CLA A;  2FYO A;  4G2M A;  1NOC B;  5T3E A;  4EPH A;  5KJS A;  2BGH A;  1T7Q A;  2DEB A;  1T7N A;  2H4T A;  5KJW A;  2II3 A;  1NDB A;  5KJU A;  1XL7 A;  2E1V A;  2FY4 A;  1E2O A;  1DPD A;  4JN3 A;  5KJT A;  2E1U A;  1T7O A;  4G0B A;  1T1U A;  4KEC A;  1PD5 A;  1Q9J A;  1XL8 A;  2FW3 A;  3FP0 A;  1NM8 A;  1XMD A;  4EYW A;  4HVM A;  1SCZ A;  5KJV A;  1DPC A;  2II4 A;  4EP9 A;  3U9F A;  2E1T A;  2ZBA A;  3L60 A;  5DUA A;  1NDF A;  3B30 A;  2JGP A;  2I9D A;  2FY3 A;  1DPB A;  5DU9 A;  2CLA A;  2RCU A;  3CLA A;  1EAE A;  1XMC A;  1S5O A;  1C4T A;  4G22 A;  1EAD A;  2H3W A;  2VSQ A;  4N72 A;  2RKT A;  2XHG A;  3U9B A;  4CLA A;  1QCA A;  3MAE A;  1Q23 A;  4KE4 A;  5FAN A;  1Q6X A;  1EAC A;  1EAF A;  3B2S A;  1NDI A;  2H3P A;  2XR7 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...