5DUSA

Crystal structure of mers-cov macro domain in complex with adp-ribose
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
165
structure length
165
Chain Sequence
MPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES
pubmed doi rcsb
molecule tags Viral protein
source organism Middle east respiratory syndrome coronavirus
molecule keywords ORF1a
total genus 58
structure length 165
sequence length 165
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2015-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5dusA00
1ZR5A 2FXKA 4UMLA 3T8WA 4K3NA 3ETIA 5FSVA 1BPMA 2EWBA 3EWQA 1LAPA 3JRUA 4J5QA 5DUSA 3EJFA 3SIJA 3V2BA 3VFQA 3GPOA 2VRIA 1BLLE 4R76A 4GVWA 1TY8A 1GYTA 3EWOA 3KQXA 5FSYA 5FSUA 4X2TA 2FG1A 2BFRA 3IIDA 4J5SA 3H8FA 3H8GA 3PEIA 4R7MA 3EJGA 3GPGA 3GQOA 5E3BA 3JZTA 4JCAA 2LGRA 5HIHA 1LANA 3EW5A 3V45A 1YD9A 3Q6ZA 4KSIA 5FSXA 1TXZA 5D8NA 4ZYQA 4K0CA 2J9AA 2X47A 4JLLA 4D86A 5AILA 5CMSA 5CB3A 5FSZA 1BPNA 4GVVA 4ETJA 2BFQA 3KR5A 3EKEA 5CBMA 4GUAA 4J4ZA 4JVVA 4TU0A 2DX6A 2XD7A 5HOLA 4ESSA 2AFCA 4ZI6A 3KZWA 3GQEA 1HJZA 3KR4A 1LAMA 4ZX8A 3EWPA 1ZR3A 3Q71A 3IJ3A 5CB5A 4KYBA 4R6TA 4ABLA 4ZY2A 4ZY1A 3SIIA 3SIGA 4ETKA 4ZX9A 1LCPA 3H8EA 3IIFA 3EWRA 4IQYA 2EEEA 1SPVA 2FAVA 3SIHA 4ABKA 1VHUA 3GPQA 2L8RA 4JGKA 4ZY0A 3KQZA 1NJRA 4J5RA 2ACFA
chains in the Genus database with same CATH superfamily
1ZR5A 2FXKA 4UMLA 3T8WA 4K3NA 3ETIA 5FSVA 1BPMA 2EWBA 3EWQA 1LAPA 3JRUA 4J5QA 5DUSA 3EJFA 3SIJA 3V2BA 3VFQA 3GPOA 2VRIA 1BLLE 4R76A 4GVWA 1TY8A 1GYTA 3EWOA 3KQXA 5FSYA 5FSUA 4X2TA 2FG1A 2JZFA 2WCTA 2BFRA 3IIDA 4J5SA 3H8FA 3H8GA 3PEIA 4R7MA 3EJGA 3GPGA 3GQOA 5E3BA 3JZTA 4JCAA 2LGRA 5HIHA 1LANA 3EW5A 3V45A 1YD9A 3Q6ZA 4KSIA 5FSXA 1TXZA 5D8NA 4ZYQA 4K0CA 2J9AA 2X47A 4JLLA 4D86A 5AILA 5CMSA 5CB3A 5FSZA 1BPNA 4GVVA 4ETJA 2BFQA 3KR5A 2KQVA 3EKEA 5CBMA 4GUAA 4J4ZA 4JVVA 4TU0A 2DX6A 2XD7A 5HOLA 4ESSA 2AFCA 4ZI6A 3KZWA 3GQEA 1HJZA 3KR4A 1LAMA 4ZX8A 3EWPA 1ZR3A 3Q71A 3IJ3A 5CB5A 4KYBA 4R6TA 4ABLA 4ZY2A 4ZY1A 3SIIA 3SIGA 4ETKA 4ZX9A 1LCPA 3H8EA 3IIFA 2RNKA 3EWRA 4IQYA 2EEEA 1SPVA 2FAVA 3SIHA 4ABKA 1VHUA 3GPQA 2W2GA 2L8RA 4JGKA 4ZY0A 2JZDA 3KQZA 1NJRA 2JZEA 4J5RA 2ACFA
chains in the Genus database with same CATH topology
1ZR5A 2FXKA 4UMLA 3T8WA 4K3NA 3ETIA 5FSVA 1BPMA 2EWBA 3EWQA 1LAPA 3JRUA 4J5QA 5DUSA 3EJFA 3SIJA 3V2BA 3VFQA 3GPOA 2VRIA 1BLLE 4R76A 4GVWA 1TY8A 1GYTA 3EWOA 3KQXA 5FSYA 5FSUA 4X2TA 2FG1A 2BFRA 3IIDA 4J5SA 3H8FA 3H8GA 3PEIA 4R7MA 3EJGA 3GPGA 3GQOA 5E3BA 3JZTA 4JCAA 2LGRA 5HIHA 1LANA 3EW5A 3V45A 1YD9A 3Q6ZA 4KSIA 5FSXA 1TXZA 5D8NA 4ZYQA 4K0CA 2J9AA 2X47A 4JLLA 4D86A 5AILA 5CMSA 5CB3A 5FSZA 1BPNA 4GVVA 4ETJA 2BFQA 3KR5A 3EKEA 5CBMA 4GUAA 4J4ZA 4JVVA 4TU0A 2DX6A 2XD7A 5HOLA 4ESSA 2AFCA 4ZI6A 3KZWA 3GQEA 1HJZA 3KR4A 1LAMA 4ZX8A 3EWPA 1ZR3A 3Q71A 3IJ3A 5CB5A 4KYBA 4R6TA 4ABLA 4ZY2A 4ZY1A 3SIIA 3SIGA 4ETKA 4ZX9A 1LCPA 3H8EA 3IIFA 3EWRA 4IQYA 2EEEA 1SPVA 2FAVA 3SIHA 4ABKA 1VHUA 3GPQA 2L8RA 4JGKA 4ZY0A 3KQZA 1NJRA 4J5RA 2ACFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZR5 A;  2FXK A;  4UML A;  3T8W A;  4K3N A;  3ETI A;  5FSV A;  1BPM A;  2EWB A;  3EWQ A;  1LAP A;  3JRU A;  4J5Q A;  5DUS A;  3EJF A;  3SIJ A;  3V2B A;  3VFQ A;  3GPO A;  2VRI A;  1BLL E;  4R76 A;  4GVW A;  1TY8 A;  1GYT A;  3EWO A;  3KQX A;  5FSY A;  5FSU A;  4X2T A;  2FG1 A;  2BFR A;  3IID A;  4J5S A;  3H8F A;  3H8G A;  3PEI A;  4R7M A;  3EJG A;  3GPG A;  3GQO A;  5E3B A;  3JZT A;  4JCA A;  2LGR A;  5HIH A;  1LAN A;  3EW5 A;  3V45 A;  1YD9 A;  3Q6Z A;  4KSI A;  5FSX A;  1TXZ A;  5D8N A;  4ZYQ A;  4K0C A;  2J9A A;  2X47 A;  4JLL A;  4D86 A;  5AIL A;  5CMS A;  5CB3 A;  5FSZ A;  1BPN A;  4GVV A;  4ETJ A;  2BFQ A;  3KR5 A;  3EKE A;  5CBM A;  4GUA A;  4J4Z A;  4JVV A;  4TU0 A;  2DX6 A;  2XD7 A;  5HOL A;  4ESS A;  2AFC A;  4ZI6 A;  3KZW A;  3GQE A;  1HJZ A;  3KR4 A;  1LAM A;  4ZX8 A;  3EWP A;  1ZR3 A;  3Q71 A;  3IJ3 A;  5CB5 A;  4KYB A;  4R6T A;  4ABL A;  4ZY2 A;  4ZY1 A;  3SII A;  3SIG A;  4ETK A;  4ZX9 A;  1LCP A;  3H8E A;  3IIF A;  3EWR A;  4IQY A;  2EEE A;  1SPV A;  2FAV A;  3SIH A;  4ABK A;  1VHU A;  3GPQ A;  2L8R A;  4JGK A;  4ZY0 A;  3KQZ A;  1NJR A;  4J5R A;  2ACF A; 
#chains in the Genus database with same CATH topology
 1ZR5 A;  2FXK A;  4UML A;  3T8W A;  4K3N A;  3ETI A;  5FSV A;  1BPM A;  2EWB A;  3EWQ A;  1LAP A;  3JRU A;  4J5Q A;  5DUS A;  3EJF A;  3SIJ A;  3V2B A;  3VFQ A;  3GPO A;  2VRI A;  1BLL E;  4R76 A;  4GVW A;  1TY8 A;  1GYT A;  3EWO A;  3KQX A;  5FSY A;  5FSU A;  4X2T A;  2FG1 A;  2JZF A;  2WCT A;  2BFR A;  3IID A;  4J5S A;  3H8F A;  3H8G A;  3PEI A;  4R7M A;  3EJG A;  3GPG A;  3GQO A;  5E3B A;  3JZT A;  4JCA A;  2LGR A;  5HIH A;  1LAN A;  3EW5 A;  3V45 A;  1YD9 A;  3Q6Z A;  4KSI A;  5FSX A;  1TXZ A;  5D8N A;  4ZYQ A;  4K0C A;  2J9A A;  2X47 A;  4JLL A;  4D86 A;  5AIL A;  5CMS A;  5CB3 A;  5FSZ A;  1BPN A;  4GVV A;  4ETJ A;  2BFQ A;  3KR5 A;  2KQV A;  3EKE A;  5CBM A;  4GUA A;  4J4Z A;  4JVV A;  4TU0 A;  2DX6 A;  2XD7 A;  5HOL A;  4ESS A;  2AFC A;  4ZI6 A;  3KZW A;  3GQE A;  1HJZ A;  3KR4 A;  1LAM A;  4ZX8 A;  3EWP A;  1ZR3 A;  3Q71 A;  3IJ3 A;  5CB5 A;  4KYB A;  4R6T A;  4ABL A;  4ZY2 A;  4ZY1 A;  3SII A;  3SIG A;  4ETK A;  4ZX9 A;  1LCP A;  3H8E A;  3IIF A;  2RNK A;  3EWR A;  4IQY A;  2EEE A;  1SPV A;  2FAV A;  3SIH A;  4ABK A;  1VHU A;  3GPQ A;  2W2G A;  2L8R A;  4JGK A;  4ZY0 A;  2JZD A;  3KQZ A;  1NJR A;  2JZE A;  4J5R A;  2ACF A; 
#chains in the Genus database with same CATH homology
 1ZR5 A;  2FXK A;  4UML A;  3T8W A;  4K3N A;  3ETI A;  5FSV A;  1BPM A;  2EWB A;  3EWQ A;  1LAP A;  3JRU A;  4J5Q A;  5DUS A;  3EJF A;  3SIJ A;  3V2B A;  3VFQ A;  3GPO A;  2VRI A;  1BLL E;  4R76 A;  4GVW A;  1TY8 A;  1GYT A;  3EWO A;  3KQX A;  5FSY A;  5FSU A;  4X2T A;  2FG1 A;  2BFR A;  3IID A;  4J5S A;  3H8F A;  3H8G A;  3PEI A;  4R7M A;  3EJG A;  3GPG A;  3GQO A;  5E3B A;  3JZT A;  4JCA A;  2LGR A;  5HIH A;  1LAN A;  3EW5 A;  3V45 A;  1YD9 A;  3Q6Z A;  4KSI A;  5FSX A;  1TXZ A;  5D8N A;  4ZYQ A;  4K0C A;  2J9A A;  2X47 A;  4JLL A;  4D86 A;  5AIL A;  5CMS A;  5CB3 A;  5FSZ A;  1BPN A;  4GVV A;  4ETJ A;  2BFQ A;  3KR5 A;  3EKE A;  5CBM A;  4GUA A;  4J4Z A;  4JVV A;  4TU0 A;  2DX6 A;  2XD7 A;  5HOL A;  4ESS A;  2AFC A;  4ZI6 A;  3KZW A;  3GQE A;  1HJZ A;  3KR4 A;  1LAM A;  4ZX8 A;  3EWP A;  1ZR3 A;  3Q71 A;  3IJ3 A;  5CB5 A;  4KYB A;  4R6T A;  4ABL A;  4ZY2 A;  4ZY1 A;  3SII A;  3SIG A;  4ETK A;  4ZX9 A;  1LCP A;  3H8E A;  3IIF A;  3EWR A;  4IQY A;  2EEE A;  1SPV A;  2FAV A;  3SIH A;  4ABK A;  1VHU A;  3GPQ A;  2L8R A;  4JGK A;  4ZY0 A;  3KQZ A;  1NJR A;  4J5R A;  2ACF A; 
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similar chains in the Genus database (?% sequence similarity)
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