5DUSA

Crystal structure of mers-cov macro domain in complex with adp-ribose
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
165
structure length
165
Chain Sequence
MPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES
pubmed doi rcsb
source organism Middle east respiratory syndrome coronavirus
molecule tags Viral protein
molecule keywords ORF1a
total genus 58
structure length 165
sequence length 165
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2015-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5dusA00
3GPGA 4X2TA 3EWPA 2BFQA 5CB3A 4ZYQA 5CMSA 1BPMA 1TY8A 3KZWA 2FAVA 4ABKA 2AFCA 3EJGA 4R6TA 2EWBA 4TU0A 4ZY2A 3EWQA 4J5QA 3KQXA 2J9AA 1SPVA 2XD7A 1NJRA 3IIFA 3PEIA 3Q6ZA 3JZTA 3JRUA 3GPQA 1LCPA 3EKEA 1ZR5A 4IQYA 4J5RA 4ZY0A 5CBMA 3V2BA 5AILA 4K0CA 3GQEA 2L8RA 1LANA 5FSYA 1LAPA 1BPNA 3V45A 3KQZA 2X47A 2FXKA 3KR4A 5HIHA 2LGRA 4J4ZA 3KR5A 3H8GA 5HOLA 5D8NA 3VFQA 5FSUA 4ABLA 3SIIA 5E3BA 4ETJA 4GUAA 3EW5A 5DUSA 4ESSA 4K3NA 4R76A 3EJFA 4JGKA 4R7MA 3EWOA 3GPOA 4ZX8A 2ACFA 3H8FA 4UMLA 1BLLE 3EWRA 3H8EA 4JLLA 1ZR3A 1HJZA 2VRIA 4ZY1A 4ZX9A 2DX6A 2BFRA 2EEEA 3SIJA 3ETIA 4GVWA 4ZI6A 5FSZA 3SIHA 1GYTA 4D86A 5FSXA 4GVVA 3GQOA 3SIGA 4KYBA 1VHUA 3T8WA 1LAMA 3IIDA 4JVVA 2FG1A 3IJ3A 5CB5A 4ETKA 1TXZA 4JCAA 4KSIA 4J5SA 3Q71A 5FSVA 1YD9A
chains in the Genus database with same CATH superfamily
3GPGA 4X2TA 3EWPA 2BFQA 5CB3A 4ZYQA 5CMSA 1BPMA 1TY8A 3KZWA 2FAVA 4ABKA 2WCTA 2W2GA 2AFCA 3EJGA 4R6TA 2EWBA 4TU0A 4ZY2A 3EWQA 4J5QA 3KQXA 2J9AA 1SPVA 2XD7A 1NJRA 3IIFA 3PEIA 3Q6ZA 3JZTA 3JRUA 3GPQA 1LCPA 3EKEA 1ZR5A 4IQYA 4J5RA 4ZY0A 5CBMA 3V2BA 2RNKA 2JZDA 5AILA 4K0CA 3GQEA 2L8RA 1LANA 5FSYA 1LAPA 1BPNA 3V45A 3KQZA 2X47A 2FXKA 3KR4A 5HIHA 2LGRA 4J4ZA 3KR5A 3H8GA 5HOLA 5D8NA 3VFQA 5FSUA 4ABLA 3SIIA 5E3BA 4ETJA 4GUAA 3EW5A 5DUSA 4ESSA 4K3NA 4R76A 3EJFA 4JGKA 4R7MA 3EWOA 3GPOA 2JZFA 4ZX8A 2ACFA 3H8FA 4UMLA 2JZEA 1BLLE 3EWRA 3H8EA 4JLLA 1ZR3A 1HJZA 2VRIA 4ZY1A 4ZX9A 2DX6A 2BFRA 2EEEA 3SIJA 3ETIA 4GVWA 4ZI6A 5FSZA 2KQVA 3SIHA 1GYTA 4D86A 5FSXA 4GVVA 3GQOA 3SIGA 4KYBA 1VHUA 3T8WA 1LAMA 3IIDA 4JVVA 2FG1A 3IJ3A 5CB5A 4ETKA 1TXZA 4JCAA 4KSIA 4J5SA 3Q71A 5FSVA 1YD9A
chains in the Genus database with same CATH topology
3GPGA 4X2TA 3EWPA 2BFQA 5CB3A 4ZYQA 5CMSA 1BPMA 1TY8A 3KZWA 2FAVA 4ABKA 2AFCA 3EJGA 4R6TA 2EWBA 4TU0A 4ZY2A 3EWQA 4J5QA 3KQXA 2J9AA 1SPVA 2XD7A 1NJRA 3IIFA 3PEIA 3Q6ZA 3JZTA 3JRUA 3GPQA 1LCPA 3EKEA 1ZR5A 4IQYA 4J5RA 4ZY0A 5CBMA 3V2BA 5AILA 4K0CA 3GQEA 2L8RA 1LANA 5FSYA 1LAPA 1BPNA 3V45A 3KQZA 2X47A 2FXKA 3KR4A 5HIHA 2LGRA 4J4ZA 3KR5A 3H8GA 5HOLA 5D8NA 3VFQA 5FSUA 4ABLA 3SIIA 5E3BA 4ETJA 4GUAA 3EW5A 5DUSA 4ESSA 4K3NA 4R76A 3EJFA 4JGKA 4R7MA 3EWOA 3GPOA 4ZX8A 2ACFA 3H8FA 4UMLA 1BLLE 3EWRA 3H8EA 4JLLA 1ZR3A 1HJZA 2VRIA 4ZY1A 4ZX9A 2DX6A 2BFRA 2EEEA 3SIJA 3ETIA 4GVWA 4ZI6A 5FSZA 3SIHA 1GYTA 4D86A 5FSXA 4GVVA 3GQOA 3SIGA 4KYBA 1VHUA 3T8WA 1LAMA 3IIDA 4JVVA 2FG1A 3IJ3A 5CB5A 4ETKA 1TXZA 4JCAA 4KSIA 4J5SA 3Q71A 5FSVA 1YD9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GPG A;  4X2T A;  3EWP A;  2BFQ A;  5CB3 A;  4ZYQ A;  5CMS A;  1BPM A;  1TY8 A;  3KZW A;  2FAV A;  4ABK A;  2AFC A;  3EJG A;  4R6T A;  2EWB A;  4TU0 A;  4ZY2 A;  3EWQ A;  4J5Q A;  3KQX A;  2J9A A;  1SPV A;  2XD7 A;  1NJR A;  3IIF A;  3PEI A;  3Q6Z A;  3JZT A;  3JRU A;  3GPQ A;  1LCP A;  3EKE A;  1ZR5 A;  4IQY A;  4J5R A;  4ZY0 A;  5CBM A;  3V2B A;  5AIL A;  4K0C A;  3GQE A;  2L8R A;  1LAN A;  5FSY A;  1LAP A;  1BPN A;  3V45 A;  3KQZ A;  2X47 A;  2FXK A;  3KR4 A;  5HIH A;  2LGR A;  4J4Z A;  3KR5 A;  3H8G A;  5HOL A;  5D8N A;  3VFQ A;  5FSU A;  4ABL A;  3SII A;  5E3B A;  4ETJ A;  4GUA A;  3EW5 A;  5DUS A;  4ESS A;  4K3N A;  4R76 A;  3EJF A;  4JGK A;  4R7M A;  3EWO A;  3GPO A;  4ZX8 A;  2ACF A;  3H8F A;  4UML A;  1BLL E;  3EWR A;  3H8E A;  4JLL A;  1ZR3 A;  1HJZ A;  2VRI A;  4ZY1 A;  4ZX9 A;  2DX6 A;  2BFR A;  2EEE A;  3SIJ A;  3ETI A;  4GVW A;  4ZI6 A;  5FSZ A;  3SIH A;  1GYT A;  4D86 A;  5FSX A;  4GVV A;  3GQO A;  3SIG A;  4KYB A;  1VHU A;  3T8W A;  1LAM A;  3IID A;  4JVV A;  2FG1 A;  3IJ3 A;  5CB5 A;  4ETK A;  1TXZ A;  4JCA A;  4KSI A;  4J5S A;  3Q71 A;  5FSV A;  1YD9 A; 
#chains in the Genus database with same CATH topology
 3GPG A;  4X2T A;  3EWP A;  2BFQ A;  5CB3 A;  4ZYQ A;  5CMS A;  1BPM A;  1TY8 A;  3KZW A;  2FAV A;  4ABK A;  2WCT A;  2W2G A;  2AFC A;  3EJG A;  4R6T A;  2EWB A;  4TU0 A;  4ZY2 A;  3EWQ A;  4J5Q A;  3KQX A;  2J9A A;  1SPV A;  2XD7 A;  1NJR A;  3IIF A;  3PEI A;  3Q6Z A;  3JZT A;  3JRU A;  3GPQ A;  1LCP A;  3EKE A;  1ZR5 A;  4IQY A;  4J5R A;  4ZY0 A;  5CBM A;  3V2B A;  2RNK A;  2JZD A;  5AIL A;  4K0C A;  3GQE A;  2L8R A;  1LAN A;  5FSY A;  1LAP A;  1BPN A;  3V45 A;  3KQZ A;  2X47 A;  2FXK A;  3KR4 A;  5HIH A;  2LGR A;  4J4Z A;  3KR5 A;  3H8G A;  5HOL A;  5D8N A;  3VFQ A;  5FSU A;  4ABL A;  3SII A;  5E3B A;  4ETJ A;  4GUA A;  3EW5 A;  5DUS A;  4ESS A;  4K3N A;  4R76 A;  3EJF A;  4JGK A;  4R7M A;  3EWO A;  3GPO A;  2JZF A;  4ZX8 A;  2ACF A;  3H8F A;  4UML A;  2JZE A;  1BLL E;  3EWR A;  3H8E A;  4JLL A;  1ZR3 A;  1HJZ A;  2VRI A;  4ZY1 A;  4ZX9 A;  2DX6 A;  2BFR A;  2EEE A;  3SIJ A;  3ETI A;  4GVW A;  4ZI6 A;  5FSZ A;  2KQV A;  3SIH A;  1GYT A;  4D86 A;  5FSX A;  4GVV A;  3GQO A;  3SIG A;  4KYB A;  1VHU A;  3T8W A;  1LAM A;  3IID A;  4JVV A;  2FG1 A;  3IJ3 A;  5CB5 A;  4ETK A;  1TXZ A;  4JCA A;  4KSI A;  4J5S A;  3Q71 A;  5FSV A;  1YD9 A; 
#chains in the Genus database with same CATH homology
 3GPG A;  4X2T A;  3EWP A;  2BFQ A;  5CB3 A;  4ZYQ A;  5CMS A;  1BPM A;  1TY8 A;  3KZW A;  2FAV A;  4ABK A;  2AFC A;  3EJG A;  4R6T A;  2EWB A;  4TU0 A;  4ZY2 A;  3EWQ A;  4J5Q A;  3KQX A;  2J9A A;  1SPV A;  2XD7 A;  1NJR A;  3IIF A;  3PEI A;  3Q6Z A;  3JZT A;  3JRU A;  3GPQ A;  1LCP A;  3EKE A;  1ZR5 A;  4IQY A;  4J5R A;  4ZY0 A;  5CBM A;  3V2B A;  5AIL A;  4K0C A;  3GQE A;  2L8R A;  1LAN A;  5FSY A;  1LAP A;  1BPN A;  3V45 A;  3KQZ A;  2X47 A;  2FXK A;  3KR4 A;  5HIH A;  2LGR A;  4J4Z A;  3KR5 A;  3H8G A;  5HOL A;  5D8N A;  3VFQ A;  5FSU A;  4ABL A;  3SII A;  5E3B A;  4ETJ A;  4GUA A;  3EW5 A;  5DUS A;  4ESS A;  4K3N A;  4R76 A;  3EJF A;  4JGK A;  4R7M A;  3EWO A;  3GPO A;  4ZX8 A;  2ACF A;  3H8F A;  4UML A;  1BLL E;  3EWR A;  3H8E A;  4JLL A;  1ZR3 A;  1HJZ A;  2VRI A;  4ZY1 A;  4ZX9 A;  2DX6 A;  2BFR A;  2EEE A;  3SIJ A;  3ETI A;  4GVW A;  4ZI6 A;  5FSZ A;  3SIH A;  1GYT A;  4D86 A;  5FSX A;  4GVV A;  3GQO A;  3SIG A;  4KYB A;  1VHU A;  3T8W A;  1LAM A;  3IID A;  4JVV A;  2FG1 A;  3IJ3 A;  5CB5 A;  4ETK A;  1TXZ A;  4JCA A;  4KSI A;  4J5S A;  3Q71 A;  5FSV A;  1YD9 A; 
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similar chains in the Genus database (?% sequence similarity)
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