5DUSA

Crystal structure of mers-cov macro domain in complex with adp-ribose
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
165
structure length
165
Chain Sequence
MPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords ORF1a
publication title Macro Domain from Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Is an Efficient ADP-ribose Binding Module: CRYSTAL STRUCTURE AND BIOCHEMICAL STUDIES
pubmed doi rcsb
source organism Middle east respiratory syndrome coronavirus
molecule tags Viral protein
total genus 58
structure length 165
sequence length 165
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2015-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5dusA00
1LANA 3T8WA 3H8EA 2XD7A 1ZR5A 4KSIA 1GYTA 3Q71A 4JLLA 5E3BA 3V45A 4ZYQA 3EWRA 3EWPA 1BLLE 2FXKA 3SIIA 3Q6ZA 2DX6A 2ACFA 2X47A 5HIHA 2J9AA 4JGKA 3ETIA 4GVVA 1YD9A 2LGRA 3KR4A 5HOLA 2BFRA 3IIFA 5FSVA 4ETKA 4JCAA 3SIJA 3EKEA 4X2TA 5DUSA 4JVVA 4R76A 5FSXA 4ZX9A 5CB3A 4K0CA 2FG1A 3PEIA 3GQEA 4D86A 1TY8A 5FSYA 3EWOA 1BPNA 3KZWA 1BPMA 5AILA 2L8RA 1LAPA 4ABLA 5CMSA 3EWQA 4ZY2A 1SPVA 4UMLA 3SIGA 4ESSA 3KQXA 4ZY1A 1TXZA 2VRIA 5FSUA 1VHUA 4ABKA 4TU0A 3VFQA 3GQOA 3IJ3A 3EJGA 1LCPA 1NJRA 5CB5A 3GPQA 4ZX8A 1ZR3A 3KR5A 4J5SA 4GVWA 2FAVA 4J5QA 4R6TA 4J5RA 4R7MA 3GPOA 3H8FA 3JRUA 4IQYA 3JZTA 3IIDA 4J4ZA 2AFCA 2EWBA 3EJFA 5FSZA 3SIHA 5D8NA 4ETJA 5CBMA 2BFQA 1LAMA 3EW5A 3V2BA 2EEEA 1HJZA 4GUAA 4KYBA 3KQZA 4ZY0A 4ZI6A 4K3NA 3GPGA 3H8GA
chains in the Genus database with same CATH superfamily
1LANA 3T8WA 3H8EA 2XD7A 1ZR5A 4KSIA 1GYTA 3Q71A 4JLLA 5E3BA 3V45A 4ZYQA 3EWRA 3EWPA 1BLLE 2FXKA 2WCTA 3SIIA 3Q6ZA 2DX6A 2ACFA 2X47A 5HIHA 2KQVA 2J9AA 4JGKA 3ETIA 4GVVA 1YD9A 2LGRA 3KR4A 5HOLA 2BFRA 3IIFA 5FSVA 4ETKA 4JCAA 3SIJA 3EKEA 4X2TA 5DUSA 4JVVA 4R76A 5FSXA 4ZX9A 5CB3A 4K0CA 2FG1A 2JZDA 3PEIA 3GQEA 4D86A 1TY8A 5FSYA 3EWOA 1BPNA 3KZWA 1BPMA 5AILA 1LAPA 4ABLA 5CMSA 3EWQA 4ZY2A 1SPVA 4UMLA 3SIGA 4ESSA 3KQXA 4ZY1A 1TXZA 2VRIA 5FSUA 1VHUA 4ABKA 4TU0A 4K3NA 3VFQA 3GQOA 3IJ3A 3EJGA 1LCPA 1NJRA 5CB5A 3GPQA 4ZX8A 1ZR3A 3KR5A 4J5SA 4GVWA 2FAVA 4J5QA 4R6TA 4J5RA 4R7MA 2JZEA 2JZFA 3GPOA 3H8FA 3JRUA 4IQYA 3JZTA 3IIDA 4J4ZA 2W2GA 2AFCA 2EWBA 3EJFA 5FSZA 3SIHA 5D8NA 4ETJA 5CBMA 2BFQA 1LAMA 3EW5A 3V2BA 2EEEA 1HJZA 4GUAA 4KYBA 2RNKA 3KQZA 4ZY0A 4ZI6A 2L8RA 3GPGA 3H8GA
chains in the Genus database with same CATH topology
1LANA 3T8WA 3H8EA 2XD7A 1ZR5A 4KSIA 1GYTA 3Q71A 4JLLA 5E3BA 3V45A 4ZYQA 3EWRA 3EWPA 1BLLE 2FXKA 3SIIA 3Q6ZA 2DX6A 2ACFA 2X47A 5HIHA 2J9AA 4JGKA 3ETIA 4GVVA 1YD9A 2LGRA 3KR4A 5HOLA 2BFRA 3IIFA 5FSVA 4ETKA 4JCAA 3SIJA 3EKEA 4X2TA 5DUSA 4JVVA 4R76A 5FSXA 4ZX9A 5CB3A 4K0CA 2FG1A 3PEIA 3GQEA 4D86A 1TY8A 5FSYA 3EWOA 1BPNA 3KZWA 1BPMA 5AILA 2L8RA 1LAPA 4ABLA 5CMSA 3EWQA 4ZY2A 1SPVA 4UMLA 3SIGA 4ESSA 3KQXA 4ZY1A 1TXZA 2VRIA 5FSUA 1VHUA 4ABKA 4TU0A 3VFQA 3GQOA 3IJ3A 3EJGA 1LCPA 1NJRA 5CB5A 3GPQA 4ZX8A 1ZR3A 3KR5A 4J5SA 4GVWA 2FAVA 4J5QA 4R6TA 4J5RA 4R7MA 3GPOA 3H8FA 3JRUA 4IQYA 3JZTA 3IIDA 4J4ZA 2AFCA 2EWBA 3EJFA 5FSZA 3SIHA 5D8NA 4ETJA 5CBMA 2BFQA 1LAMA 3EW5A 3V2BA 2EEEA 1HJZA 4GUAA 4KYBA 3KQZA 4ZY0A 4ZI6A 4K3NA 3GPGA 3H8GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LAN A;  3T8W A;  3H8E A;  2XD7 A;  1ZR5 A;  4KSI A;  1GYT A;  3Q71 A;  4JLL A;  5E3B A;  3V45 A;  4ZYQ A;  3EWR A;  3EWP A;  1BLL E;  2FXK A;  3SII A;  3Q6Z A;  2DX6 A;  2ACF A;  2X47 A;  5HIH A;  2J9A A;  4JGK A;  3ETI A;  4GVV A;  1YD9 A;  2LGR A;  3KR4 A;  5HOL A;  2BFR A;  3IIF A;  5FSV A;  4ETK A;  4JCA A;  3SIJ A;  3EKE A;  4X2T A;  5DUS A;  4JVV A;  4R76 A;  5FSX A;  4ZX9 A;  5CB3 A;  4K0C A;  2FG1 A;  3PEI A;  3GQE A;  4D86 A;  1TY8 A;  5FSY A;  3EWO A;  1BPN A;  3KZW A;  1BPM A;  5AIL A;  2L8R A;  1LAP A;  4ABL A;  5CMS A;  3EWQ A;  4ZY2 A;  1SPV A;  4UML A;  3SIG A;  4ESS A;  3KQX A;  4ZY1 A;  1TXZ A;  2VRI A;  5FSU A;  1VHU A;  4ABK A;  4TU0 A;  3VFQ A;  3GQO A;  3IJ3 A;  3EJG A;  1LCP A;  1NJR A;  5CB5 A;  3GPQ A;  4ZX8 A;  1ZR3 A;  3KR5 A;  4J5S A;  4GVW A;  2FAV A;  4J5Q A;  4R6T A;  4J5R A;  4R7M A;  3GPO A;  3H8F A;  3JRU A;  4IQY A;  3JZT A;  3IID A;  4J4Z A;  2AFC A;  2EWB A;  3EJF A;  5FSZ A;  3SIH A;  5D8N A;  4ETJ A;  5CBM A;  2BFQ A;  1LAM A;  3EW5 A;  3V2B A;  2EEE A;  1HJZ A;  4GUA A;  4KYB A;  3KQZ A;  4ZY0 A;  4ZI6 A;  4K3N A;  3GPG A;  3H8G A; 
#chains in the Genus database with same CATH topology
 1LAN A;  3T8W A;  3H8E A;  2XD7 A;  1ZR5 A;  4KSI A;  1GYT A;  3Q71 A;  4JLL A;  5E3B A;  3V45 A;  4ZYQ A;  3EWR A;  3EWP A;  1BLL E;  2FXK A;  2WCT A;  3SII A;  3Q6Z A;  2DX6 A;  2ACF A;  2X47 A;  5HIH A;  2KQV A;  2J9A A;  4JGK A;  3ETI A;  4GVV A;  1YD9 A;  2LGR A;  3KR4 A;  5HOL A;  2BFR A;  3IIF A;  5FSV A;  4ETK A;  4JCA A;  3SIJ A;  3EKE A;  4X2T A;  5DUS A;  4JVV A;  4R76 A;  5FSX A;  4ZX9 A;  5CB3 A;  4K0C A;  2FG1 A;  2JZD A;  3PEI A;  3GQE A;  4D86 A;  1TY8 A;  5FSY A;  3EWO A;  1BPN A;  3KZW A;  1BPM A;  5AIL A;  1LAP A;  4ABL A;  5CMS A;  3EWQ A;  4ZY2 A;  1SPV A;  4UML A;  3SIG A;  4ESS A;  3KQX A;  4ZY1 A;  1TXZ A;  2VRI A;  5FSU A;  1VHU A;  4ABK A;  4TU0 A;  4K3N A;  3VFQ A;  3GQO A;  3IJ3 A;  3EJG A;  1LCP A;  1NJR A;  5CB5 A;  3GPQ A;  4ZX8 A;  1ZR3 A;  3KR5 A;  4J5S A;  4GVW A;  2FAV A;  4J5Q A;  4R6T A;  4J5R A;  4R7M A;  2JZE A;  2JZF A;  3GPO A;  3H8F A;  3JRU A;  4IQY A;  3JZT A;  3IID A;  4J4Z A;  2W2G A;  2AFC A;  2EWB A;  3EJF A;  5FSZ A;  3SIH A;  5D8N A;  4ETJ A;  5CBM A;  2BFQ A;  1LAM A;  3EW5 A;  3V2B A;  2EEE A;  1HJZ A;  4GUA A;  4KYB A;  2RNK A;  3KQZ A;  4ZY0 A;  4ZI6 A;  2L8R A;  3GPG A;  3H8G A; 
#chains in the Genus database with same CATH homology
 1LAN A;  3T8W A;  3H8E A;  2XD7 A;  1ZR5 A;  4KSI A;  1GYT A;  3Q71 A;  4JLL A;  5E3B A;  3V45 A;  4ZYQ A;  3EWR A;  3EWP A;  1BLL E;  2FXK A;  3SII A;  3Q6Z A;  2DX6 A;  2ACF A;  2X47 A;  5HIH A;  2J9A A;  4JGK A;  3ETI A;  4GVV A;  1YD9 A;  2LGR A;  3KR4 A;  5HOL A;  2BFR A;  3IIF A;  5FSV A;  4ETK A;  4JCA A;  3SIJ A;  3EKE A;  4X2T A;  5DUS A;  4JVV A;  4R76 A;  5FSX A;  4ZX9 A;  5CB3 A;  4K0C A;  2FG1 A;  3PEI A;  3GQE A;  4D86 A;  1TY8 A;  5FSY A;  3EWO A;  1BPN A;  3KZW A;  1BPM A;  5AIL A;  2L8R A;  1LAP A;  4ABL A;  5CMS A;  3EWQ A;  4ZY2 A;  1SPV A;  4UML A;  3SIG A;  4ESS A;  3KQX A;  4ZY1 A;  1TXZ A;  2VRI A;  5FSU A;  1VHU A;  4ABK A;  4TU0 A;  3VFQ A;  3GQO A;  3IJ3 A;  3EJG A;  1LCP A;  1NJR A;  5CB5 A;  3GPQ A;  4ZX8 A;  1ZR3 A;  3KR5 A;  4J5S A;  4GVW A;  2FAV A;  4J5Q A;  4R6T A;  4J5R A;  4R7M A;  3GPO A;  3H8F A;  3JRU A;  4IQY A;  3JZT A;  3IID A;  4J4Z A;  2AFC A;  2EWB A;  3EJF A;  5FSZ A;  3SIH A;  5D8N A;  4ETJ A;  5CBM A;  2BFQ A;  1LAM A;  3EW5 A;  3V2B A;  2EEE A;  1HJZ A;  4GUA A;  4KYB A;  3KQZ A;  4ZY0 A;  4ZI6 A;  4K3N A;  3GPG A;  3H8G A; 
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similar chains in the Genus database (?% sequence similarity)
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