5DV2A

Crystal structure of human cnot6l in complex with cytidine-5'-monophosphate
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
372
structure length
335
Chain Sequence
LPPRPWITLKERDSASFTVMCYNVLCDKYATRQLYGYCPSWALNWEYRKKGIMEEIVNCDADIISLQEVETEQYFTLFLPALKERGYDGFFSPKSRAKIMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQVAMANSDGSEAMLNRVMTKDNIGVAVVLEVHKELFKQLLIVANAHMHWDPEYSDVKLIQTMMFVSEVKNILEKASIPLVLCADLNSLPDSGVVEYLSNGGVADNHKDFKELRYNECLMNFSRITHGFQLKSAYENNLMPYTNYTFDFKGVIDYIFYSKTHMNVLGVLGPLDPQWLVENNITGCPHPHIPSDHFSLLTQLELHP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for inhibition of the deadenylase activity of human CNOT6L
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CCR4-NOT transcription complex subunit 6-like
total genus 117
structure length 335
sequence length 372
ec nomenclature ec 3.1.13.4: Poly(A)-specific ribonuclease.
pdb deposition date 2015-09-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 5dv2A00
5INQA 5DFFA 2XSWA 2O3HA 4FVAA 4GZ0A 1Y21A 4CMNA 5DV4A 1NTFA 5DFIA 4QHEA 2JC5A 4B5GA 2F1NA 3DNIA 2EI9A 2A42B 5INNA 3G8VA 4FPVA 3CJCD 3G00A 3N9VA 2DDTA 3W2YA 2ISIA 4L20A 5J3ZA 4AWNA 1YJHA 5DG0A 2A40B 4B5HA 4C1RA 3G4TA 5A7IA 1ATND 3G91A 3GA6A 2UYRX 1BIXA 3NR8A 2A3ZB 5INPA 2DDRA 2DNJA 1I9YA 1AKOA 3W2XA 4B5FA 3G3CA 1E9NA 4F1IA 3MTCA 3L1WA 2VOAA 2D1KB 5A7JA 4K6LF 2F2FB 1DE9A 2V0SA 4F1HA 4CMLA 3NGOA 3NGNA 5HT2A 4F1RA 3G2CA 1SR4B 4LNDA 1VYBA 4L21A 5CFGA 3K55A 3G1KA 5INMA 4RUWA 3G0RA 5J8NA 4GZ1A 5EWTA 2A41B 3WCXA 4B5MA 1SI6X 1I9ZA 5J3SA 4B5IA 5CFEA 4IEMA 1DE8A 4GYZA 4A9CA 3I41A 5INLA 5INOA 2O3CA 4QHDA 2DDSA 3I46A 2J63A 5J42A 5DFJA 4QH9A 3U8UA 4GEWA 4GZ2A 3FZIA 4PUQA 3NGQA 3MPRA 5DV2A 3I5VA 4L1ZA 3G2DA 4B5JA 3G6SA 3G38A 4F1HB 5DFHA 5INKA 1HD7A 4JG3A 2V0RA 3W3DB 1WDUA 1ZWXA 2JC4A 4L1YA 3TEBA 3G0AA 2IMQX 5J3PA 1DEWA 1DNKA 3G3YA 3I48A
chains in the Genus database with same CATH superfamily
5INQA 5DFFA 2XSWA 2O3HA 4FVAA 4GZ0A 1Y21A 4CMNA 5DV4A 1NTFA 5DFIA 4QHEA 2JC5A 4B5GA 2F1NA 3DNIA 2EI9A 2A42B 5INNA 3G8VA 4FPVA 3CJCD 3G00A 3N9VA 2DDTA 3W2YA 2ISIA 4L20A 5J3ZA 4AWNA 1YJHA 5DG0A 2A40B 4B5HA 4C1RA 3G4TA 5A7IA 1ATND 3G91A 3GA6A 2UYRX 1BIXA 3NR8A 2A3ZB 5INPA 2DDRA 2DNJA 1I9YA 1AKOA 3W2XA 4B5FA 3G3CA 1E9NA 4F1IA 3MTCA 3L1WA 2VOAA 2D1KB 5A7JA 4K6LF 2F2FB 1DE9A 2V0SA 4F1HA 4CMLA 3NGOA 3NGNA 5HT2A 4F1RA 3G2CA 1SR4B 4LNDA 1VYBA 4L21A 5CFGA 3K55A 3G1KA 5INMA 4RUWA 3G0RA 5J8NA 4GZ1A 5EWTA 2A41B 3WCXA 4B5MA 1SI6X 1I9ZA 5J3SA 4B5IA 5CFEA 4IEMA 1DE8A 4GYZA 4A9CA 3I41A 5INLA 5INOA 2O3CA 4QHDA 2DDSA 3I46A 2J63A 5J42A 5DFJA 4QH9A 3U8UA 4GEWA 4GZ2A 3FZIA 4PUQA 3NGQA 3MPRA 5DV2A 3I5VA 4L1ZA 3G2DA 4B5JA 3G6SA 3G38A 4F1HB 5DFHA 5INKA 1HD7A 4JG3A 2V0RA 3W3DB 1WDUA 1ZWXA 2JC4A 4L1YA 3TEBA 3G0AA 2IMQX 5J3PA 1DEWA 1DNKA 3G3YA 3I48A
chains in the Genus database with same CATH topology
5INQA 5DFFA 2XSWA 2O3HA 4FVAA 4GZ0A 1Y21A 4CMNA 5DV4A 1NTFA 5DFIA 4QHEA 2JC5A 4B5GA 2F1NA 3DNIA 2EI9A 2A42B 5INNA 3G8VA 4FPVA 3CJCD 3G00A 3N9VA 2DDTA 3W2YA 2ISIA 4L20A 5J3ZA 4AWNA 1YJHA 5DG0A 2A40B 4B5HA 4C1RA 3G4TA 5A7IA 1ATND 3G91A 3GA6A 2UYRX 1BIXA 3NR8A 2A3ZB 5INPA 2DDRA 2DNJA 1I9YA 1AKOA 3W2XA 4B5FA 3G3CA 1E9NA 4F1IA 3MTCA 3L1WA 2VOAA 2D1KB 5A7JA 4K6LF 2F2FB 1DE9A 2V0SA 4F1HA 4CMLA 3NGOA 3NGNA 5HT2A 4F1RA 3G2CA 1SR4B 4LNDA 1VYBA 4L21A 5CFGA 3K55A 3G1KA 5INMA 4RUWA 3G0RA 5J8NA 4GZ1A 5EWTA 2A41B 3WCXA 4B5MA 1SI6X 1I9ZA 5J3SA 4B5IA 5CFEA 4IEMA 1DE8A 4GYZA 4A9CA 3I41A 5INLA 5INOA 2O3CA 4QHDA 2DDSA 3I46A 2J63A 5J42A 5DFJA 4QH9A 3U8UA 4GEWA 4GZ2A 3FZIA 4PUQA 3NGQA 3MPRA 5DV2A 3I5VA 4L1ZA 3G2DA 4B5JA 3G6SA 3G38A 4F1HB 5DFHA 5INKA 1HD7A 4JG3A 2V0RA 3W3DB 1WDUA 1ZWXA 2JC4A 4L1YA 3TEBA 3G0AA 2IMQX 5J3PA 1DEWA 1DNKA 3G3YA 3I48A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5INQ A;  5DFF A;  2XSW A;  2O3H A;  4FVA A;  4GZ0 A;  1Y21 A;  4CMN A;  5DV4 A;  1NTF A;  5DFI A;  4QHE A;  2JC5 A;  4B5G A;  2F1N A;  3DNI A;  2EI9 A;  2A42 B;  5INN A;  3G8V A;  4FPV A;  3CJC D;  3G00 A;  3N9V A;  2DDT A;  3W2Y A;  2ISI A;  4L20 A;  5J3Z A;  4AWN A;  1YJH A;  5DG0 A;  2A40 B;  4B5H A;  4C1R A;  3G4T A;  5A7I A;  1ATN D;  3G91 A;  3GA6 A;  2UYR X;  1BIX A;  3NR8 A;  2A3Z B;  5INP A;  2DDR A;  2DNJ A;  1I9Y A;  1AKO A;  3W2X A;  4B5F A;  3G3C A;  1E9N A;  4F1I A;  3MTC A;  3L1W A;  2VOA A;  2D1K B;  5A7J A;  4K6L F;  2F2F B;  1DE9 A;  2V0S A;  4F1H A;  4CML A;  3NGO A;  3NGN A;  5HT2 A;  4F1R A;  3G2C A;  1SR4 B;  4LND A;  1VYB A;  4L21 A;  5CFG A;  3K55 A;  3G1K A;  5INM A;  4RUW A;  3G0R A;  5J8N A;  4GZ1 A;  5EWT A;  2A41 B;  3WCX A;  4B5M A;  1SI6 X;  1I9Z A;  5J3S A;  4B5I A;  5CFE A;  4IEM A;  1DE8 A;  4GYZ A;  4A9C A;  3I41 A;  5INL A;  5INO A;  2O3C A;  4QHD A;  2DDS A;  3I46 A;  2J63 A;  5J42 A;  5DFJ A;  4QH9 A;  3U8U A;  4GEW A;  4GZ2 A;  3FZI A;  4PUQ A;  3NGQ A;  3MPR A;  5DV2 A;  3I5V A;  4L1Z A;  3G2D A;  4B5J A;  3G6S A;  3G38 A;  4F1H B;  5DFH A;  5INK A;  1HD7 A;  4JG3 A;  2V0R A;  3W3D B;  1WDU A;  1ZWX A;  2JC4 A;  4L1Y A;  3TEB A;  3G0A A;  2IMQ X;  5J3P A;  1DEW A;  1DNK A;  3G3Y A;  3I48 A; 
#chains in the Genus database with same CATH topology
 5INQ A;  5DFF A;  2XSW A;  2O3H A;  4FVA A;  4GZ0 A;  1Y21 A;  4CMN A;  5DV4 A;  1NTF A;  5DFI A;  4QHE A;  2JC5 A;  4B5G A;  2F1N A;  3DNI A;  2EI9 A;  2A42 B;  5INN A;  3G8V A;  4FPV A;  3CJC D;  3G00 A;  3N9V A;  2DDT A;  3W2Y A;  2ISI A;  4L20 A;  5J3Z A;  4AWN A;  1YJH A;  5DG0 A;  2A40 B;  4B5H A;  4C1R A;  3G4T A;  5A7I A;  1ATN D;  3G91 A;  3GA6 A;  2UYR X;  1BIX A;  3NR8 A;  2A3Z B;  5INP A;  2DDR A;  2DNJ A;  1I9Y A;  1AKO A;  3W2X A;  4B5F A;  3G3C A;  1E9N A;  4F1I A;  3MTC A;  3L1W A;  2VOA A;  2D1K B;  5A7J A;  4K6L F;  2F2F B;  1DE9 A;  2V0S A;  4F1H A;  4CML A;  3NGO A;  3NGN A;  5HT2 A;  4F1R A;  3G2C A;  1SR4 B;  4LND A;  1VYB A;  4L21 A;  5CFG A;  3K55 A;  3G1K A;  5INM A;  4RUW A;  3G0R A;  5J8N A;  4GZ1 A;  5EWT A;  2A41 B;  3WCX A;  4B5M A;  1SI6 X;  1I9Z A;  5J3S A;  4B5I A;  5CFE A;  4IEM A;  1DE8 A;  4GYZ A;  4A9C A;  3I41 A;  5INL A;  5INO A;  2O3C A;  4QHD A;  2DDS A;  3I46 A;  2J63 A;  5J42 A;  5DFJ A;  4QH9 A;  3U8U A;  4GEW A;  4GZ2 A;  3FZI A;  4PUQ A;  3NGQ A;  3MPR A;  5DV2 A;  3I5V A;  4L1Z A;  3G2D A;  4B5J A;  3G6S A;  3G38 A;  4F1H B;  5DFH A;  5INK A;  1HD7 A;  4JG3 A;  2V0R A;  3W3D B;  1WDU A;  1ZWX A;  2JC4 A;  4L1Y A;  3TEB A;  3G0A A;  2IMQ X;  5J3P A;  1DEW A;  1DNK A;  3G3Y A;  3I48 A; 
#chains in the Genus database with same CATH homology
 5INQ A;  5DFF A;  2XSW A;  2O3H A;  4FVA A;  4GZ0 A;  1Y21 A;  4CMN A;  5DV4 A;  1NTF A;  5DFI A;  4QHE A;  2JC5 A;  4B5G A;  2F1N A;  3DNI A;  2EI9 A;  2A42 B;  5INN A;  3G8V A;  4FPV A;  3CJC D;  3G00 A;  3N9V A;  2DDT A;  3W2Y A;  2ISI A;  4L20 A;  5J3Z A;  4AWN A;  1YJH A;  5DG0 A;  2A40 B;  4B5H A;  4C1R A;  3G4T A;  5A7I A;  1ATN D;  3G91 A;  3GA6 A;  2UYR X;  1BIX A;  3NR8 A;  2A3Z B;  5INP A;  2DDR A;  2DNJ A;  1I9Y A;  1AKO A;  3W2X A;  4B5F A;  3G3C A;  1E9N A;  4F1I A;  3MTC A;  3L1W A;  2VOA A;  2D1K B;  5A7J A;  4K6L F;  2F2F B;  1DE9 A;  2V0S A;  4F1H A;  4CML A;  3NGO A;  3NGN A;  5HT2 A;  4F1R A;  3G2C A;  1SR4 B;  4LND A;  1VYB A;  4L21 A;  5CFG A;  3K55 A;  3G1K A;  5INM A;  4RUW A;  3G0R A;  5J8N A;  4GZ1 A;  5EWT A;  2A41 B;  3WCX A;  4B5M A;  1SI6 X;  1I9Z A;  5J3S A;  4B5I A;  5CFE A;  4IEM A;  1DE8 A;  4GYZ A;  4A9C A;  3I41 A;  5INL A;  5INO A;  2O3C A;  4QHD A;  2DDS A;  3I46 A;  2J63 A;  5J42 A;  5DFJ A;  4QH9 A;  3U8U A;  4GEW A;  4GZ2 A;  3FZI A;  4PUQ A;  3NGQ A;  3MPR A;  5DV2 A;  3I5V A;  4L1Z A;  3G2D A;  4B5J A;  3G6S A;  3G38 A;  4F1H B;  5DFH A;  5INK A;  1HD7 A;  4JG3 A;  2V0R A;  3W3D B;  1WDU A;  1ZWX A;  2JC4 A;  4L1Y A;  3TEB A;  3G0A A;  2IMQ X;  5J3P A;  1DEW A;  1DNK A;  3G3Y A;  3I48 A; 
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