5E5BA

Crystal structure of human spt16 n-terminal domain
Total Genus 150
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
431
structure length
431
Chain Sequence
AVTLDKDAYYRRVKRLYSNWRKGEDEYANVDAIVVSVGVDEEIVYAKSTALQTWLFGYELTDTIMVFCDDKIIFMASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIKESKNGKKIGVFSKDKFPGEFMKSWNDCLNKEGFDKIDISAVVAYTIAVKEDGELNLMKKAASITSEVFNKFFKERVMEIVDADEKVRHSKLAESVEKAIEEKKYLAGADPSTVEMCYPPIIQSGGNYNLKFSVVSDKNHMHFGAITCAMGIRFKSYCSNLVRTLMVDPSQEVQENYNFLLQLQEELLKELRHGVKICDVYNAVMDVVKKQKPELLNKITKNLGFGMGIEFREGSLVINSKNQYKLKKGMVFSINLGFSDLTNKEGKKPEEKTYALFIGDTVLVDEDGPATVLTSVKKKVKNVGIFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the human histone chaperone FACT Spt16 N-terminal domain.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords FACT complex subunit SPT16
total genus 150
structure length 431
sequence length 431
ec nomenclature
pdb deposition date 2015-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF14826 FACT-Spt16_Nlob FACT complex subunit SPT16 N-terminal lobe domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5e5bA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5e5bA02
3OVKA 3L7GA 3PEBA 2BHBA 4FLIA 2GZ5A 2GG0A 2V3YA 5E2CA 4ZWUA 2GG2A 4FLKA 4FUKA 3PKCA 4U70A 2BB7A 2B3KA 4S2TP 2GGBA 2Q93A 4KM3A 4MATA 1WBQA 1XGSA 1C21A 4IKTA 2EA4A 1B6AA 2EVCA 1KQ9A 1C22A 1BN5A 2Q94A 1YW7A 5JHUA 4ZNGA 3TB5A 1YJ3A 2B3LA 4IDYA 4S01A 2Q95A 3IU9A 2GG7A 3Q6DA 2V3ZA 4FLJA 1C24A 1W2MA 5CDVA 4U1BA 3FMQA 4IKUA 2Q92A 1YVMA 3TAVA 2GTXA 3MATA 1YW9A 4IU6A 2BHCA 1WN1A 3QOCA 2GU6A 4FKCA 5CDLA 1XGMA 1W7VA 4RGZ1 1R5HA 2P98A 4PNCA 2DFIA 2EA2A 4OOKA 1O0XA 2HOWA 1YW8A 5FCHA 2Q96A 5CNXA 3PKAA 4U6CA 3CB6A 4ZWOA 1QXZA 2ADUA 2BWXA 4IKSA 1N51A 5CDEA 2P99A 3CTZA 2GA2A 4HXXA 3PN9A 2V6CA 1WLRA 5E5BA 3RORA 3FM3A 4U73A 5CLSA 3PKDA 4ZWPA 2MATA 4JUQA 1Y1NA 3BITA 4QR8A 4RZYA 5JI6A 1QXWA 1A16A 2BWYA 3IG4A 2G6PA 5D6FA 4A6WA 3IU7A 2EVOA 2NQ7A 1QZYA 1B59A 4PV4A 3IL0A 2GU4A 3MR1A 3IU8A 4IF7A 4U6WA 2BWWA 3L24A 1M35A 2BWUA 5FCFA 4FO7A 5D6EA 2BWVA 1JAWA 2B3HA 1WL9A 4RZZA 2GG8A 4IPAA 1XGOA 2GG9A 4S00A 2IW2A 1MATA 3FMRA 1KP0A 2OKNA 1KQ0A 4FLLA 5CIKA 2P9AA 2OAZA 3S6BA 3BIQA 2GU5A 2V3XA 2BHDA 4S2RP 2BN7A 3BIPA 1XNZA 3O5VA 1R58A 4U75A 4IECA 4U71A 3MX6A 4U6JA 4B28A 2GG5A 3I7MA 2BWSA 4U6ZA 3PKEA 4U76A 2GG3A 3PKBA 1R5GA 1PV9A 4FO8A 1C23A 1WY2A 1C27A 2BWTA 1WL6A 4A6VA 1QXYA 1WKMA 2EVMA 5CE6A 4U6EA 4Z7MA 4U69A 4R60A 2GGCA 3CB5A 1XGNA 3OOOA 2NQ6A 5JFRA 2BH3A 2BHAA 1CHMA 4IKRA 2Q8KA 4EGEA 2GU7A 3RVAA 2ZSGA 1BOAA 3D27A
chains in the Genus database with same CATH superfamily
3OVKA 3L7GA 3PEBA 2BHBA 4FLIA 2GZ5A 2GG0A 2V3YA 5E2CA 4ZWUA 2GG2A 4FLKA 4FUKA 3PKCA 4U70A 2BB7A 2B3KA 4S2TP 2GGBA 2Q93A 4KM3A 4MATA 1WBQA 1XGSA 1C21A 4IKTA 2EA4A 1B6AA 2EVCA 1KQ9A 1C22A 1BN5A 2Q94A 1YW7A 5JHUA 4ZNGA 3TB5A 1YJ3A 2B3LA 4IDYA 4S01A 2Q95A 3IU9A 2GG7A 3Q6DA 2V3ZA 4FLJA 1C24A 1W2MA 5CDVA 4U1BA 3FMQA 4IKUA 2Q92A 1YVMA 3TAVA 2GTXA 3MATA 1YW9A 4IU6A 2BHCA 1WN1A 3QOCA 2GU6A 4FKCA 5CDLA 1XGMA 1W7VA 4RGZ1 1R5HA 2P98A 4PNCA 2DFIA 2EA2A 4OOKA 1O0XA 2HOWA 1YW8A 5FCHA 2Q96A 5CNXA 3PKAA 4U6CA 3CB6A 4ZWOA 1QXZA 2ADUA 2BWXA 4IKSA 1N51A 5CDEA 2P99A 3CTZA 2GA2A 4HXXA 3PN9A 2V6CA 1WLRA 5E5BA 3RORA 3FM3A 4U73A 5CLSA 3PKDA 4ZWPA 2MATA 4JUQA 1Y1NA 3BITA 4QR8A 4RZYA 5JI6A 1QXWA 1A16A 2BWYA 3IG4A 2G6PA 5D6FA 4A6WA 3IU7A 2EVOA 2NQ7A 1QZYA 1B59A 4PV4A 3IL0A 2GU4A 3MR1A 3IU8A 4IF7A 4U6WA 2BWWA 3L24A 1M35A 2BWUA 5FCFA 4FO7A 5D6EA 2BWVA 1JAWA 2B3HA 1WL9A 4RZZA 2GG8A 4IPAA 1XGOA 2GG9A 4S00A 2IW2A 1MATA 3FMRA 1KP0A 2OKNA 1KQ0A 4FLLA 5CIKA 2P9AA 2OAZA 3S6BA 3BIQA 2GU5A 2V3XA 2BHDA 4S2RP 2BN7A 3BIPA 1XNZA 3O5VA 1R58A 4U75A 4IECA 4U71A 3MX6A 4U6JA 4B28A 2GG5A 3I7MA 2BWSA 4U6ZA 3PKEA 4U76A 2GG3A 3PKBA 1R5GA 1PV9A 4FO8A 1C23A 1WY2A 1C27A 2BWTA 1WL6A 4A6VA 1QXYA 1WKMA 2EVMA 5CE6A 4U6EA 4Z7MA 4U69A 4R60A 2GGCA 3CB5A 1XGNA 3OOOA 2NQ6A 5JFRA 2BH3A 2BHAA 1CHMA 4IKRA 2Q8KA 4EGEA 2GU7A 3RVAA 2ZSGA 1BOAA 3D27A
chains in the Genus database with same CATH topology
3OVKA 3L7GA 3PEBA 2BHBA 4FLIA 2GZ5A 2GG0A 2V3YA 5E2CA 4ZWUA 2GG2A 4FLKA 4FUKA 3PKCA 4U70A 2BB7A 2B3KA 4S2TP 2GGBA 2Q93A 4KM3A 4MATA 1WBQA 1XGSA 1C21A 4IKTA 2EA4A 1B6AA 2EVCA 1KQ9A 1C22A 1BN5A 2Q94A 1YW7A 5JHUA 4ZNGA 3TB5A 1YJ3A 2B3LA 4IDYA 4S01A 2Q95A 3IU9A 2GG7A 3Q6DA 2V3ZA 4FLJA 1C24A 1W2MA 5CDVA 4U1BA 3FMQA 4IKUA 2Q92A 1YVMA 3TAVA 2GTXA 3MATA 1YW9A 4IU6A 2BHCA 1WN1A 3QOCA 2GU6A 4FKCA 5CDLA 1XGMA 1W7VA 4RGZ1 1R5HA 2P98A 4PNCA 2DFIA 2EA2A 4OOKA 1O0XA 2HOWA 1YW8A 5FCHA 2Q96A 5CNXA 3PKAA 4U6CA 3CB6A 4ZWOA 1QXZA 2ADUA 2BWXA 4IKSA 1N51A 5CDEA 2P99A 3CTZA 2GA2A 4HXXA 3PN9A 2V6CA 1WLRA 5E5BA 3RORA 3FM3A 4U73A 5CLSA 3PKDA 4ZWPA 2MATA 4JUQA 1Y1NA 3BITA 4QR8A 4RZYA 5JI6A 1QXWA 1A16A 2BWYA 3IG4A 2G6PA 5D6FA 4A6WA 3IU7A 2EVOA 2NQ7A 1QZYA 1B59A 4PV4A 3IL0A 2GU4A 3MR1A 3IU8A 4IF7A 4U6WA 2BWWA 3L24A 1M35A 2BWUA 5FCFA 4FO7A 5D6EA 2BWVA 1JAWA 2B3HA 1WL9A 4RZZA 2GG8A 4IPAA 1XGOA 2GG9A 4S00A 2IW2A 1MATA 3FMRA 1KP0A 2OKNA 1KQ0A 4FLLA 5CIKA 2P9AA 2OAZA 3S6BA 3BIQA 2GU5A 2V3XA 2BHDA 4S2RP 2BN7A 3BIPA 1XNZA 3O5VA 1R58A 4U75A 4IECA 4U71A 3MX6A 4U6JA 4B28A 2GG5A 3I7MA 2BWSA 4U6ZA 3PKEA 4U76A 2GG3A 3PKBA 1R5GA 1PV9A 4FO8A 1C23A 1WY2A 1C27A 2BWTA 1WL6A 4A6VA 1QXYA 1WKMA 2EVMA 5CE6A 4U6EA 4Z7MA 4U69A 4R60A 2GGCA 3CB5A 1XGNA 3OOOA 2NQ6A 5JFRA 2BH3A 2BHAA 1CHMA 4IKRA 2Q8KA 4EGEA 2GU7A 3RVAA 2ZSGA 1BOAA 3D27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OVK A;  3L7G A;  3PEB A;  2BHB A;  4FLI A;  2GZ5 A;  2GG0 A;  2V3Y A;  5E2C A;  4ZWU A;  2GG2 A;  4FLK A;  4FUK A;  3PKC A;  4U70 A;  2BB7 A;  2B3K A;  4S2T P;  2GGB A;  2Q93 A;  4KM3 A;  4MAT A;  1WBQ A;  1XGS A;  1C21 A;  4IKT A;  2EA4 A;  1B6A A;  2EVC A;  1KQ9 A;  1C22 A;  1BN5 A;  2Q94 A;  1YW7 A;  5JHU A;  4ZNG A;  3TB5 A;  1YJ3 A;  2B3L A;  4IDY A;  4S01 A;  2Q95 A;  3IU9 A;  2GG7 A;  3Q6D A;  2V3Z A;  4FLJ A;  1C24 A;  1W2M A;  5CDV A;  4U1B A;  3FMQ A;  4IKU A;  2Q92 A;  1YVM A;  3TAV A;  2GTX A;  3MAT A;  1YW9 A;  4IU6 A;  2BHC A;  1WN1 A;  3QOC A;  2GU6 A;  4FKC A;  5CDL A;  1XGM A;  1W7V A;  4RGZ 1;  1R5H A;  2P98 A;  4PNC A;  2DFI A;  2EA2 A;  4OOK A;  1O0X A;  2HOW A;  1YW8 A;  5FCH A;  2Q96 A;  5CNX A;  3PKA A;  4U6C A;  3CB6 A;  4ZWO A;  1QXZ A;  2ADU A;  2BWX A;  4IKS A;  1N51 A;  5CDE A;  2P99 A;  3CTZ A;  2GA2 A;  4HXX A;  3PN9 A;  2V6C A;  1WLR A;  5E5B A;  3ROR A;  3FM3 A;  4U73 A;  5CLS A;  3PKD A;  4ZWP A;  2MAT A;  4JUQ A;  1Y1N A;  3BIT A;  4QR8 A;  4RZY A;  5JI6 A;  1QXW A;  1A16 A;  2BWY A;  3IG4 A;  2G6P A;  5D6F A;  4A6W A;  3IU7 A;  2EVO A;  2NQ7 A;  1QZY A;  1B59 A;  4PV4 A;  3IL0 A;  2GU4 A;  3MR1 A;  3IU8 A;  4IF7 A;  4U6W A;  2BWW A;  3L24 A;  1M35 A;  2BWU A;  5FCF A;  4FO7 A;  5D6E A;  2BWV A;  1JAW A;  2B3H A;  1WL9 A;  4RZZ A;  2GG8 A;  4IPA A;  1XGO A;  2GG9 A;  4S00 A;  2IW2 A;  1MAT A;  3FMR A;  1KP0 A;  2OKN A;  1KQ0 A;  4FLL A;  5CIK A;  2P9A A;  2OAZ A;  3S6B A;  3BIQ A;  2GU5 A;  2V3X A;  2BHD A;  4S2R P;  2BN7 A;  3BIP A;  1XNZ A;  3O5V A;  1R58 A;  4U75 A;  4IEC A;  4U71 A;  3MX6 A;  4U6J A;  4B28 A;  2GG5 A;  3I7M A;  2BWS A;  4U6Z A;  3PKE A;  4U76 A;  2GG3 A;  3PKB A;  1R5G A;  1PV9 A;  4FO8 A;  1C23 A;  1WY2 A;  1C27 A;  2BWT A;  1WL6 A;  4A6V A;  1QXY A;  1WKM A;  2EVM A;  5CE6 A;  4U6E A;  4Z7M A;  4U69 A;  4R60 A;  2GGC A;  3CB5 A;  1XGN A;  3OOO A;  2NQ6 A;  5JFR A;  2BH3 A;  2BHA A;  1CHM A;  4IKR A;  2Q8K A;  4EGE A;  2GU7 A;  3RVA A;  2ZSG A;  1BOA A;  3D27 A; 
#chains in the Genus database with same CATH topology
 3OVK A;  3L7G A;  3PEB A;  2BHB A;  4FLI A;  2GZ5 A;  2GG0 A;  2V3Y A;  5E2C A;  4ZWU A;  2GG2 A;  4FLK A;  4FUK A;  3PKC A;  4U70 A;  2BB7 A;  2B3K A;  4S2T P;  2GGB A;  2Q93 A;  4KM3 A;  4MAT A;  1WBQ A;  1XGS A;  1C21 A;  4IKT A;  2EA4 A;  1B6A A;  2EVC A;  1KQ9 A;  1C22 A;  1BN5 A;  2Q94 A;  1YW7 A;  5JHU A;  4ZNG A;  3TB5 A;  1YJ3 A;  2B3L A;  4IDY A;  4S01 A;  2Q95 A;  3IU9 A;  2GG7 A;  3Q6D A;  2V3Z A;  4FLJ A;  1C24 A;  1W2M A;  5CDV A;  4U1B A;  3FMQ A;  4IKU A;  2Q92 A;  1YVM A;  3TAV A;  2GTX A;  3MAT A;  1YW9 A;  4IU6 A;  2BHC A;  1WN1 A;  3QOC A;  2GU6 A;  4FKC A;  5CDL A;  1XGM A;  1W7V A;  4RGZ 1;  1R5H A;  2P98 A;  4PNC A;  2DFI A;  2EA2 A;  4OOK A;  1O0X A;  2HOW A;  1YW8 A;  5FCH A;  2Q96 A;  5CNX A;  3PKA A;  4U6C A;  3CB6 A;  4ZWO A;  1QXZ A;  2ADU A;  2BWX A;  4IKS A;  1N51 A;  5CDE A;  2P99 A;  3CTZ A;  2GA2 A;  4HXX A;  3PN9 A;  2V6C A;  1WLR A;  5E5B A;  3ROR A;  3FM3 A;  4U73 A;  5CLS A;  3PKD A;  4ZWP A;  2MAT A;  4JUQ A;  1Y1N A;  3BIT A;  4QR8 A;  4RZY A;  5JI6 A;  1QXW A;  1A16 A;  2BWY A;  3IG4 A;  2G6P A;  5D6F A;  4A6W A;  3IU7 A;  2EVO A;  2NQ7 A;  1QZY A;  1B59 A;  4PV4 A;  3IL0 A;  2GU4 A;  3MR1 A;  3IU8 A;  4IF7 A;  4U6W A;  2BWW A;  3L24 A;  1M35 A;  2BWU A;  5FCF A;  4FO7 A;  5D6E A;  2BWV A;  1JAW A;  2B3H A;  1WL9 A;  4RZZ A;  2GG8 A;  4IPA A;  1XGO A;  2GG9 A;  4S00 A;  2IW2 A;  1MAT A;  3FMR A;  1KP0 A;  2OKN A;  1KQ0 A;  4FLL A;  5CIK A;  2P9A A;  2OAZ A;  3S6B A;  3BIQ A;  2GU5 A;  2V3X A;  2BHD A;  4S2R P;  2BN7 A;  3BIP A;  1XNZ A;  3O5V A;  1R58 A;  4U75 A;  4IEC A;  4U71 A;  3MX6 A;  4U6J A;  4B28 A;  2GG5 A;  3I7M A;  2BWS A;  4U6Z A;  3PKE A;  4U76 A;  2GG3 A;  3PKB A;  1R5G A;  1PV9 A;  4FO8 A;  1C23 A;  1WY2 A;  1C27 A;  2BWT A;  1WL6 A;  4A6V A;  1QXY A;  1WKM A;  2EVM A;  5CE6 A;  4U6E A;  4Z7M A;  4U69 A;  4R60 A;  2GGC A;  3CB5 A;  1XGN A;  3OOO A;  2NQ6 A;  5JFR A;  2BH3 A;  2BHA A;  1CHM A;  4IKR A;  2Q8K A;  4EGE A;  2GU7 A;  3RVA A;  2ZSG A;  1BOA A;  3D27 A; 
#chains in the Genus database with same CATH homology
 3OVK A;  3L7G A;  3PEB A;  2BHB A;  4FLI A;  2GZ5 A;  2GG0 A;  2V3Y A;  5E2C A;  4ZWU A;  2GG2 A;  4FLK A;  4FUK A;  3PKC A;  4U70 A;  2BB7 A;  2B3K A;  4S2T P;  2GGB A;  2Q93 A;  4KM3 A;  4MAT A;  1WBQ A;  1XGS A;  1C21 A;  4IKT A;  2EA4 A;  1B6A A;  2EVC A;  1KQ9 A;  1C22 A;  1BN5 A;  2Q94 A;  1YW7 A;  5JHU A;  4ZNG A;  3TB5 A;  1YJ3 A;  2B3L A;  4IDY A;  4S01 A;  2Q95 A;  3IU9 A;  2GG7 A;  3Q6D A;  2V3Z A;  4FLJ A;  1C24 A;  1W2M A;  5CDV A;  4U1B A;  3FMQ A;  4IKU A;  2Q92 A;  1YVM A;  3TAV A;  2GTX A;  3MAT A;  1YW9 A;  4IU6 A;  2BHC A;  1WN1 A;  3QOC A;  2GU6 A;  4FKC A;  5CDL A;  1XGM A;  1W7V A;  4RGZ 1;  1R5H A;  2P98 A;  4PNC A;  2DFI A;  2EA2 A;  4OOK A;  1O0X A;  2HOW A;  1YW8 A;  5FCH A;  2Q96 A;  5CNX A;  3PKA A;  4U6C A;  3CB6 A;  4ZWO A;  1QXZ A;  2ADU A;  2BWX A;  4IKS A;  1N51 A;  5CDE A;  2P99 A;  3CTZ A;  2GA2 A;  4HXX A;  3PN9 A;  2V6C A;  1WLR A;  5E5B A;  3ROR A;  3FM3 A;  4U73 A;  5CLS A;  3PKD A;  4ZWP A;  2MAT A;  4JUQ A;  1Y1N A;  3BIT A;  4QR8 A;  4RZY A;  5JI6 A;  1QXW A;  1A16 A;  2BWY A;  3IG4 A;  2G6P A;  5D6F A;  4A6W A;  3IU7 A;  2EVO A;  2NQ7 A;  1QZY A;  1B59 A;  4PV4 A;  3IL0 A;  2GU4 A;  3MR1 A;  3IU8 A;  4IF7 A;  4U6W A;  2BWW A;  3L24 A;  1M35 A;  2BWU A;  5FCF A;  4FO7 A;  5D6E A;  2BWV A;  1JAW A;  2B3H A;  1WL9 A;  4RZZ A;  2GG8 A;  4IPA A;  1XGO A;  2GG9 A;  4S00 A;  2IW2 A;  1MAT A;  3FMR A;  1KP0 A;  2OKN A;  1KQ0 A;  4FLL A;  5CIK A;  2P9A A;  2OAZ A;  3S6B A;  3BIQ A;  2GU5 A;  2V3X A;  2BHD A;  4S2R P;  2BN7 A;  3BIP A;  1XNZ A;  3O5V A;  1R58 A;  4U75 A;  4IEC A;  4U71 A;  3MX6 A;  4U6J A;  4B28 A;  2GG5 A;  3I7M A;  2BWS A;  4U6Z A;  3PKE A;  4U76 A;  2GG3 A;  3PKB A;  1R5G A;  1PV9 A;  4FO8 A;  1C23 A;  1WY2 A;  1C27 A;  2BWT A;  1WL6 A;  4A6V A;  1QXY A;  1WKM A;  2EVM A;  5CE6 A;  4U6E A;  4Z7M A;  4U69 A;  4R60 A;  2GGC A;  3CB5 A;  1XGN A;  3OOO A;  2NQ6 A;  5JFR A;  2BH3 A;  2BHA A;  1CHM A;  4IKR A;  2Q8K A;  4EGE A;  2GU7 A;  3RVA A;  2ZSG A;  1BOA A;  3D27 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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