5ERRA

Gephe in complex with mg(2+) - adp
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
418
structure length
414
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 104
structure length 414
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5errA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5errA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5errA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5errA02
2F7YA 4XCWA 5ERVA 4TWGA 4UUWA 2G4RA 4UUXA 3RFQA 4TK4A 4CTAA 3MCJA 1DI7A 4PD1A 2NRPA 1XI8A 2NQVA 1O8QA 3MCHA 2G2CA 2NQSA 1O8NA 2FU3A 1Y5EA 4PD0A 2NRSA 5ERRA 5ERTA 2NQUA 4CTAB 4LHBA 5ERUA 2QQ1A 2IS8A 4TK3A 3IWTA 1WU2A 4NWOA 3MCIA 1FC5A 1G8RA 2F7WA 2NQMA 3OI9A 2NQKA 1UUXA 1UUYA 2FTSA 1JLJA 2X3LA 3TCRA 4U91A 2NQRA 2PBQA 5G2SA 1DI6A 1O8OA 1MKZA 1IHCA 2NQNA 2NQQA 1T3EA 2NROA 3KBQA 3K6AA 1G8LA 1EAVA 1R2KA 3PZYA 4CT9A 4UOCA 5ERQA 4TK1A 4U90A 4CT8A 5ERSA 1UZ5A 5G2RA
chains in the Genus database with same CATH superfamily
2F7YA 4XCWA 5ERVA 4TWGA 4UUWA 2G4RA 4UUXA 3RFQA 4TK4A 1IW7D 5DMHA 4CTAA 3MCJA 3DQQA 1DI7A 4PD1A 2NRPA 1XI8A 2NQVA 1O8QA 3MCHA 2G2CA 2NQSA 1O8NA 2FU3A 1Y5EA 4PD0A 1I6VD 2NRSA 5ERRA 5ERTA 2NQUA 4CTAB 4LHBA 5ERUA 2QQ1A 2IS8A 4TK3A 3JSYA 3IWTA 1WU2A 4NWOA 3MCIA 1FC5A 1G8RA 2F7WA 2NQMA 3OI9A 2NQKA 1UUXA 1UUYA 1HQMD 2FTSA 1JLJA 2X3LA 3TCRA 4U91A 2NQRA 2PBQA 5G2SA 1DI6A 1O8OA 1MKZA 1IHCA 2NQNA 2NQQA 1T3EA 2NROA 5D8HB 3KBQA 3K6AA 1G8LA 1EAVA 1R2KA 3PZYA 1YZYA 4CT9A 4UOCA 5ERQA 4TK1A 5D6GA 4NWBA 4U90A 4CT8A 5ERSA 1UZ5A 5G2RA
chains in the Genus database with same CATH topology
2F7YA 4XCWA 5ERVA 4TWGA 4UUWA 2G4RA 4UUXA 3RFQA 4TK4A 1IW7D 4CTAA 3MCJA 1DI7A 4PD1A 2NRPA 1XI8A 2NQVA 1O8QA 3MCHA 2G2CA 2NQSA 1O8NA 2FU3A 1Y5EA 4PD0A 1I6VD 2NRSA 5ERRA 5ERTA 2NQUA 4CTAB 4LHBA 5ERUA 2QQ1A 2IS8A 4TK3A 3JSYA 3IWTA 1WU2A 4NWOA 3MCIA 1FC5A 1G8RA 2F7WA 2NQMA 3OI9A 2NQKA 1UUXA 1UUYA 1HQMD 2FTSA 1JLJA 2X3LA 3TCRA 4U91A 2NQRA 2PBQA 5G2SA 1DI6A 1O8OA 1MKZA 1IHCA 2NQNA 2NQQA 1T3EA 2NROA 5D8HB 3KBQA 3K6AA 1G8LA 1EAVA 1R2KA 3PZYA 4CT9A 4UOCA 5ERQA 4TK1A 5D6GA 4NWBA 4U90A 4CT8A 5ERSA 1UZ5A 5G2RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F7Y A;  4XCW A;  5ERV A;  4TWG A;  4UUW A;  2G4R A;  4UUX A;  3RFQ A;  4TK4 A;  4CTA A;  3MCJ A;  1DI7 A;  4PD1 A;  2NRP A;  1XI8 A;  2NQV A;  1O8Q A;  3MCH A;  2G2C A;  2NQS A;  1O8N A;  2FU3 A;  1Y5E A;  4PD0 A;  2NRS A;  5ERR A;  5ERT A;  2NQU A;  4CTA B;  4LHB A;  5ERU A;  2QQ1 A;  2IS8 A;  4TK3 A;  3IWT A;  1WU2 A;  4NWO A;  3MCI A;  1FC5 A;  1G8R A;  2F7W A;  2NQM A;  3OI9 A;  2NQK A;  1UUX A;  1UUY A;  2FTS A;  1JLJ A;  2X3L A;  3TCR A;  4U91 A;  2NQR A;  2PBQ A;  5G2S A;  1DI6 A;  1O8O A;  1MKZ A;  1IHC A;  2NQN A;  2NQQ A;  1T3E A;  2NRO A;  3KBQ A;  3K6A A;  1G8L A;  1EAV A;  1R2K A;  3PZY A;  4CT9 A;  4UOC A;  5ERQ A;  4TK1 A;  4U90 A;  4CT8 A;  5ERS A;  1UZ5 A;  5G2R A; 
#chains in the Genus database with same CATH topology
 2F7Y A;  4XCW A;  5ERV A;  4TWG A;  4UUW A;  2G4R A;  4UUX A;  3RFQ A;  4TK4 A;  1IW7 D;  5DMH A;  4CTA A;  3MCJ A;  3DQQ A;  1DI7 A;  4PD1 A;  2NRP A;  1XI8 A;  2NQV A;  1O8Q A;  3MCH A;  2G2C A;  2NQS A;  1O8N A;  2FU3 A;  1Y5E A;  4PD0 A;  1I6V D;  2NRS A;  5ERR A;  5ERT A;  2NQU A;  4CTA B;  4LHB A;  5ERU A;  2QQ1 A;  2IS8 A;  4TK3 A;  3JSY A;  3IWT A;  1WU2 A;  4NWO A;  3MCI A;  1FC5 A;  1G8R A;  2F7W A;  2NQM A;  3OI9 A;  2NQK A;  1UUX A;  1UUY A;  1HQM D;  2FTS A;  1JLJ A;  2X3L A;  3TCR A;  4U91 A;  2NQR A;  2PBQ A;  5G2S A;  1DI6 A;  1O8O A;  1MKZ A;  1IHC A;  2NQN A;  2NQQ A;  1T3E A;  2NRO A;  5D8H B;  3KBQ A;  3K6A A;  1G8L A;  1EAV A;  1R2K A;  3PZY A;  1YZY A;  4CT9 A;  4UOC A;  5ERQ A;  4TK1 A;  5D6G A;  4NWB A;  4U90 A;  4CT8 A;  5ERS A;  1UZ5 A;  5G2R A; 
#chains in the Genus database with same CATH homology
 2F7Y A;  4XCW A;  5ERV A;  4TWG A;  4UUW A;  2G4R A;  4UUX A;  3RFQ A;  4TK4 A;  1IW7 D;  4CTA A;  3MCJ A;  1DI7 A;  4PD1 A;  2NRP A;  1XI8 A;  2NQV A;  1O8Q A;  3MCH A;  2G2C A;  2NQS A;  1O8N A;  2FU3 A;  1Y5E A;  4PD0 A;  1I6V D;  2NRS A;  5ERR A;  5ERT A;  2NQU A;  4CTA B;  4LHB A;  5ERU A;  2QQ1 A;  2IS8 A;  4TK3 A;  3JSY A;  3IWT A;  1WU2 A;  4NWO A;  3MCI A;  1FC5 A;  1G8R A;  2F7W A;  2NQM A;  3OI9 A;  2NQK A;  1UUX A;  1UUY A;  1HQM D;  2FTS A;  1JLJ A;  2X3L A;  3TCR A;  4U91 A;  2NQR A;  2PBQ A;  5G2S A;  1DI6 A;  1O8O A;  1MKZ A;  1IHC A;  2NQN A;  2NQQ A;  1T3E A;  2NRO A;  5D8H B;  3KBQ A;  3K6A A;  1G8L A;  1EAV A;  1R2K A;  3PZY A;  4CT9 A;  4UOC A;  5ERQ A;  4TK1 A;  5D6G A;  4NWB A;  4U90 A;  4CT8 A;  5ERS A;  1UZ5 A;  5G2R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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