5ERVA

Ternary complex of gephe - adp - tungsten cluster
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
418
structure length
413
Chain Sequence
SPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis.
pubmed doi rcsb
molecule tags Transferase
source organism Rattus norvegicus
molecule keywords Gephyrin
total genus 103
structure length 413
sequence length 418
ec nomenclature ec 2.10.1.1: Molybdopterin molybdotransferase.
pdb deposition date 2015-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00994 MoCF_biosynth Probable molybdopterin binding domain
A PF03453 MoeA_N MoeA N-terminal region (domain I and II)
A PF03454 MoeA_C MoeA C-terminal region (domain IV)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.340.10 Mainly Beta Beta Barrel Beta-clip MoeA, C-terminal, domain IV 5ervA04
2.170.190.11 Mainly Beta Beta Complex Molybdopterin biosynthesis moeA protein; domain 3 Molybdopterin biosynthesis moea protein, domain 3. 5ervA03
3.40.980.10 Alpha Beta 3-Layer(aba) Sandwich Molybdenum Cofactor Biosythetic Enzyme; Chain A MoaB/Mog-like domain 5ervA01
3.90.105.10 Alpha Beta Alpha-Beta Complex Molybdopterin biosynthesis moea protein, domain 2 Molybdopterin biosynthesis moea protein, domain 2 5ervA02
3MCHA 4XCWA 1EAVA 4CT8A 1UZ5A 4PD1A 3OI9A 5G2SA 2NQKA 5ERRA 2NQSA 4LHBA 4TWGA 1UUXA 1FC5A 3RFQA 2NQMA 5ERUA 1O8OA 2PBQA 2NQQA 2F7WA 1O8QA 1IHCA 4PD0A 5ERQA 1Y5EA 4U91A 1XI8A 3KBQA 2NQNA 3IWTA 2G4RA 2IS8A 4CTAA 1G8RA 2NROA 2NQUA 4TK4A 2NRPA 5ERVA 1T3EA 1WU2A 2FU3A 4U90A 1JLJA 2NQRA 4UUXA 2NRSA 2F7YA 3K6AA 5ERSA 4CTAB 5ERTA 4CT9A 1G8LA 2FTSA 2QQ1A 4TK3A 4UUWA 1DI7A 4TK1A 3PZYA 2G2CA 3MCIA 1MKZA 1O8NA 1DI6A 2NQVA 4UOCA 1R2KA 4NWOA 1UUYA 5G2RA 3MCJA 2X3LA 3TCRA
chains in the Genus database with same CATH superfamily
3MCHA 4XCWA 1EAVA 4CT8A 1UZ5A 4PD1A 3OI9A 5G2SA 2NQKA 1HQMD 5ERRA 2NQSA 4LHBA 4TWGA 1UUXA 1FC5A 3RFQA 2NQMA 5ERUA 1O8OA 2PBQA 2NQQA 2F7WA 1O8QA 1IHCA 4PD0A 5ERQA 1Y5EA 4U91A 5D8HB 1XI8A 3KBQA 2NQNA 1YZYA 3IWTA 3DQQA 2G4RA 5D6GA 5DMHA 2IS8A 4CTAA 1I6VD 1G8RA 2NROA 2NQUA 4TK4A 2NRPA 5ERVA 1T3EA 1WU2A 2FU3A 4U90A 1JLJA 2NQRA 4UUXA 2NRSA 2F7YA 3K6AA 5ERSA 4CTAB 5ERTA 4CT9A 3JSYA 1G8LA 2FTSA 2QQ1A 1IW7D 4TK3A 4UUWA 1DI7A 4TK1A 3PZYA 2G2CA 3MCIA 1MKZA 1O8NA 1DI6A 2NQVA 4UOCA 1R2KA 4NWOA 1UUYA 5G2RA 3MCJA 2X3LA 3TCRA 4NWBA
chains in the Genus database with same CATH topology
3MCHA 4XCWA 1EAVA 4CT8A 1UZ5A 4PD1A 3OI9A 5G2SA 2NQKA 1HQMD 5ERRA 2NQSA 4LHBA 4TWGA 1UUXA 1FC5A 3RFQA 2NQMA 5ERUA 1O8OA 2PBQA 2NQQA 2F7WA 1O8QA 1IHCA 4PD0A 5ERQA 1Y5EA 4U91A 5D8HB 1XI8A 3KBQA 2NQNA 3IWTA 2G4RA 5D6GA 2IS8A 4CTAA 1I6VD 1G8RA 2NROA 2NQUA 4TK4A 2NRPA 5ERVA 1T3EA 1WU2A 2FU3A 4U90A 1JLJA 2NQRA 4UUXA 2NRSA 2F7YA 3K6AA 5ERSA 4CTAB 5ERTA 4CT9A 3JSYA 1G8LA 2FTSA 2QQ1A 1IW7D 4TK3A 4UUWA 1DI7A 4TK1A 3PZYA 2G2CA 3MCIA 1MKZA 1O8NA 1DI6A 2NQVA 4UOCA 1R2KA 4NWOA 1UUYA 5G2RA 3MCJA 2X3LA 3TCRA 4NWBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MCH A;  4XCW A;  1EAV A;  4CT8 A;  1UZ5 A;  4PD1 A;  3OI9 A;  5G2S A;  2NQK A;  5ERR A;  2NQS A;  4LHB A;  4TWG A;  1UUX A;  1FC5 A;  3RFQ A;  2NQM A;  5ERU A;  1O8O A;  2PBQ A;  2NQQ A;  2F7W A;  1O8Q A;  1IHC A;  4PD0 A;  5ERQ A;  1Y5E A;  4U91 A;  1XI8 A;  3KBQ A;  2NQN A;  3IWT A;  2G4R A;  2IS8 A;  4CTA A;  1G8R A;  2NRO A;  2NQU A;  4TK4 A;  2NRP A;  5ERV A;  1T3E A;  1WU2 A;  2FU3 A;  4U90 A;  1JLJ A;  2NQR A;  4UUX A;  2NRS A;  2F7Y A;  3K6A A;  5ERS A;  4CTA B;  5ERT A;  4CT9 A;  1G8L A;  2FTS A;  2QQ1 A;  4TK3 A;  4UUW A;  1DI7 A;  4TK1 A;  3PZY A;  2G2C A;  3MCI A;  1MKZ A;  1O8N A;  1DI6 A;  2NQV A;  4UOC A;  1R2K A;  4NWO A;  1UUY A;  5G2R A;  3MCJ A;  2X3L A;  3TCR A; 
#chains in the Genus database with same CATH topology
 3MCH A;  4XCW A;  1EAV A;  4CT8 A;  1UZ5 A;  4PD1 A;  3OI9 A;  5G2S A;  2NQK A;  1HQM D;  5ERR A;  2NQS A;  4LHB A;  4TWG A;  1UUX A;  1FC5 A;  3RFQ A;  2NQM A;  5ERU A;  1O8O A;  2PBQ A;  2NQQ A;  2F7W A;  1O8Q A;  1IHC A;  4PD0 A;  5ERQ A;  1Y5E A;  4U91 A;  5D8H B;  1XI8 A;  3KBQ A;  2NQN A;  1YZY A;  3IWT A;  3DQQ A;  2G4R A;  5D6G A;  5DMH A;  2IS8 A;  4CTA A;  1I6V D;  1G8R A;  2NRO A;  2NQU A;  4TK4 A;  2NRP A;  5ERV A;  1T3E A;  1WU2 A;  2FU3 A;  4U90 A;  1JLJ A;  2NQR A;  4UUX A;  2NRS A;  2F7Y A;  3K6A A;  5ERS A;  4CTA B;  5ERT A;  4CT9 A;  3JSY A;  1G8L A;  2FTS A;  2QQ1 A;  1IW7 D;  4TK3 A;  4UUW A;  1DI7 A;  4TK1 A;  3PZY A;  2G2C A;  3MCI A;  1MKZ A;  1O8N A;  1DI6 A;  2NQV A;  4UOC A;  1R2K A;  4NWO A;  1UUY A;  5G2R A;  3MCJ A;  2X3L A;  3TCR A;  4NWB A; 
#chains in the Genus database with same CATH homology
 3MCH A;  4XCW A;  1EAV A;  4CT8 A;  1UZ5 A;  4PD1 A;  3OI9 A;  5G2S A;  2NQK A;  1HQM D;  5ERR A;  2NQS A;  4LHB A;  4TWG A;  1UUX A;  1FC5 A;  3RFQ A;  2NQM A;  5ERU A;  1O8O A;  2PBQ A;  2NQQ A;  2F7W A;  1O8Q A;  1IHC A;  4PD0 A;  5ERQ A;  1Y5E A;  4U91 A;  5D8H B;  1XI8 A;  3KBQ A;  2NQN A;  3IWT A;  2G4R A;  5D6G A;  2IS8 A;  4CTA A;  1I6V D;  1G8R A;  2NRO A;  2NQU A;  4TK4 A;  2NRP A;  5ERV A;  1T3E A;  1WU2 A;  2FU3 A;  4U90 A;  1JLJ A;  2NQR A;  4UUX A;  2NRS A;  2F7Y A;  3K6A A;  5ERS A;  4CTA B;  5ERT A;  4CT9 A;  3JSY A;  1G8L A;  2FTS A;  2QQ1 A;  1IW7 D;  4TK3 A;  4UUW A;  1DI7 A;  4TK1 A;  3PZY A;  2G2C A;  3MCI A;  1MKZ A;  1O8N A;  1DI6 A;  2NQV A;  4UOC A;  1R2K A;  4NWO A;  1UUY A;  5G2R A;  3MCJ A;  2X3L A;  3TCR A;  4NWB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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