5EYTA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in complex with amp
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
478
structure length
472
Chain Sequence
EFEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNITI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Lyase
molecule keywords Adenylosuccinate lyase
total genus 181
structure length 472
sequence length 478
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eytA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eytA02
3KDYA 1VDKA 4ADLA 2O6YA 1C3UA 3BHGA 5HW2A 1C3CA 2QVEA 1KQ7A 2J91A 1YFMA 2PTQA 4V2RA 2RJSA 2O7BA 1TJVA 1FUOA 1U16A 4BABA 1T6PA 4EEIA 2O7DA 1I0AA 4NLEA 1XWOA 3UNVA 2O78A 1K62A 1FUQA 4NSLA 1GK3A 1B8FA 3TV2A 2O7FA 1K7WA 1EB4A 2RJRA 2PTSA 4BAAA 3RD8A 4FFXA 2X75A 1DOFA 1AUWA 1GKMA 1JSWA 1RE5A 2NYNA 4HGVA 4C5RA 1T6JA 1J3UA 3QBPA 1HY0A 4V2QA 2E9FA 2OHYA 3GTDA 1GKJA 1YISA 1U15A 1FURA 4C5UA 3C8TA 3R6YA 4FLCA 2YIIA 3RRPA 4MX2A 4EFCA 3CZOA 1FUPA 5F91A 1W27A 2QGAB 1TJ7A 2HVGA 4APAA 3R6VA 1YFEA 2NYFA 2PFMA 5F92A 5EYTA 4C6GA 1GK2A 1HY1A 3GZHA 3NZ4A 2PTRA 3NO9A 3OCFA 4C5SA 1Q5NA 5EYVA 3OCEA 4CQ5A 4APBA 1TJUA 2FUSA 2VD6A 3KDZA 3E04A 1DCNA 4ADMA 2O7EA 1Y2MA 1TJWA 3R6QA 5D6BA
chains in the Genus database with same CATH superfamily
3KDYA 1VDKA 4ADLA 2O6YA 1C3UA 3BHGA 5HW2A 1C3CA 2QVEA 1KQ7A 2J91A 1YFMA 2PTQA 4V2RA 2RJSA 2O7BA 5M0JA 1TJVA 1XLYA 1FUOA 1U16A 4BABA 1T6PA 4EEIA 2O7DA 1I0AA 4NLEA 1XMDA 2VSFA 1XWOA 3UNVA 2O78A 1K62A 1FUQA 4NSLA 1GK3A 1B8FA 5H8WA 3TV2A 2O7FA 1K7WA 1EB4A 2RJRA 2PTSA 4BAAA 3RD8A 4FFXA 2X75A 1DOFA 5M0IA 1AUWA 1GKMA 1XMCA 1JSWA 1RE5A 1XL8A 2NYNA 4HGVA 4C5RA 1T6JA 1XL7A 2FELA 1J3UA 3QBPA 1HY0A 4V2QA 2E9FA 2OHYA 3GTDA 1GKJA 1YISA 1U15A 1FURA 4C5UA 3C8TA 3R6YA 4FLCA 2YIIA 3RRPA 4MX2A 4EFCA 3CRVA 4A15A 3CZOA 1FUPA 2VL7A 5F91A 1W27A 2QGAB 1TJ7A 2HVGA 4APAA 3R6VA 1YFEA 2NYFA 2PFMA 5F92A 5EYTA 4C6GA 1GK2A 1HY1A 3GZHA 3NZ4A 2PTRA 3NO9A 3OCFA 4C5SA 2FENA 1Q5NA 5EYVA 3OCEA 4CQ5A 4APBA 1TJUA 2FUSA 2VD6A 3KDZA 4WNLA 3E04A 1DCNA 4ADMA 2O7EA 1Y2MA 1TJWA 3R6QA 5D6BA 3CRW1
chains in the Genus database with same CATH topology
3KDYA 1VDKA 4ADLA 2O6YA 1C3UA 3BHGA 5HW2A 1C3CA 2QVEA 1KQ7A 2J91A 1YFMA 2PTQA 4V2RA 2RJSA 2O7BA 1TJVA 1FUOA 1U16A 4BABA 1T6PA 4EEIA 2O7DA 1I0AA 4NLEA 1XWOA 3UNVA 2O78A 1K62A 1FUQA 4NSLA 1GK3A 1B8FA 3TV2A 2O7FA 1K7WA 1EB4A 2RJRA 2PTSA 4BAAA 3RD8A 4FFXA 2X75A 1DOFA 1AUWA 1GKMA 1JSWA 1RE5A 2NYNA 4HGVA 4C5RA 1T6JA 1J3UA 3QBPA 1HY0A 4V2QA 2E9FA 2OHYA 3GTDA 1GKJA 1YISA 1U15A 1FURA 4C5UA 3C8TA 3R6YA 4FLCA 2YIIA 3RRPA 4MX2A 4EFCA 3CZOA 1FUPA 5F91A 1W27A 2QGAB 1TJ7A 2HVGA 4APAA 3R6VA 1YFEA 2NYFA 2PFMA 5F92A 5EYTA 4C6GA 1GK2A 1HY1A 3GZHA 3NZ4A 2PTRA 3NO9A 3OCFA 4C5SA 1Q5NA 5EYVA 3OCEA 4CQ5A 4APBA 1TJUA 2FUSA 2VD6A 3KDZA 3E04A 1DCNA 4ADMA 2O7EA 1Y2MA 1TJWA 3R6QA 5D6BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KDY A;  1VDK A;  4ADL A;  2O6Y A;  1C3U A;  3BHG A;  5HW2 A;  1C3C A;  2QVE A;  1KQ7 A;  2J91 A;  1YFM A;  2PTQ A;  4V2R A;  2RJS A;  2O7B A;  1TJV A;  1FUO A;  1U16 A;  4BAB A;  1T6P A;  4EEI A;  2O7D A;  1I0A A;  4NLE A;  1XWO A;  3UNV A;  2O78 A;  1K62 A;  1FUQ A;  4NSL A;  1GK3 A;  1B8F A;  3TV2 A;  2O7F A;  1K7W A;  1EB4 A;  2RJR A;  2PTS A;  4BAA A;  3RD8 A;  4FFX A;  2X75 A;  1DOF A;  1AUW A;  1GKM A;  1JSW A;  1RE5 A;  2NYN A;  4HGV A;  4C5R A;  1T6J A;  1J3U A;  3QBP A;  1HY0 A;  4V2Q A;  2E9F A;  2OHY A;  3GTD A;  1GKJ A;  1YIS A;  1U15 A;  1FUR A;  4C5U A;  3C8T A;  3R6Y A;  4FLC A;  2YII A;  3RRP A;  4MX2 A;  4EFC A;  3CZO A;  1FUP A;  5F91 A;  1W27 A;  2QGA B;  1TJ7 A;  2HVG A;  4APA A;  3R6V A;  1YFE A;  2NYF A;  2PFM A;  5F92 A;  5EYT A;  4C6G A;  1GK2 A;  1HY1 A;  3GZH A;  3NZ4 A;  2PTR A;  3NO9 A;  3OCF A;  4C5S A;  1Q5N A;  5EYV A;  3OCE A;  4CQ5 A;  4APB A;  1TJU A;  2FUS A;  2VD6 A;  3KDZ A;  3E04 A;  1DCN A;  4ADM A;  2O7E A;  1Y2M A;  1TJW A;  3R6Q A;  5D6B A; 
#chains in the Genus database with same CATH topology
 3KDY A;  1VDK A;  4ADL A;  2O6Y A;  1C3U A;  3BHG A;  5HW2 A;  1C3C A;  2QVE A;  1KQ7 A;  2J91 A;  1YFM A;  2PTQ A;  4V2R A;  2RJS A;  2O7B A;  5M0J A;  1TJV A;  1XLY A;  1FUO A;  1U16 A;  4BAB A;  1T6P A;  4EEI A;  2O7D A;  1I0A A;  4NLE A;  1XMD A;  2VSF A;  1XWO A;  3UNV A;  2O78 A;  1K62 A;  1FUQ A;  4NSL A;  1GK3 A;  1B8F A;  5H8W A;  3TV2 A;  2O7F A;  1K7W A;  1EB4 A;  2RJR A;  2PTS A;  4BAA A;  3RD8 A;  4FFX A;  2X75 A;  1DOF A;  5M0I A;  1AUW A;  1GKM A;  1XMC A;  1JSW A;  1RE5 A;  1XL8 A;  2NYN A;  4HGV A;  4C5R A;  1T6J A;  1XL7 A;  2FEL A;  1J3U A;  3QBP A;  1HY0 A;  4V2Q A;  2E9F A;  2OHY A;  3GTD A;  1GKJ A;  1YIS A;  1U15 A;  1FUR A;  4C5U A;  3C8T A;  3R6Y A;  4FLC A;  2YII A;  3RRP A;  4MX2 A;  4EFC A;  3CRV A;  4A15 A;  3CZO A;  1FUP A;  2VL7 A;  5F91 A;  1W27 A;  2QGA B;  1TJ7 A;  2HVG A;  4APA A;  3R6V A;  1YFE A;  2NYF A;  2PFM A;  5F92 A;  5EYT A;  4C6G A;  1GK2 A;  1HY1 A;  3GZH A;  3NZ4 A;  2PTR A;  3NO9 A;  3OCF A;  4C5S A;  2FEN A;  1Q5N A;  5EYV A;  3OCE A;  4CQ5 A;  4APB A;  1TJU A;  2FUS A;  2VD6 A;  3KDZ A;  4WNL A;  3E04 A;  1DCN A;  4ADM A;  2O7E A;  1Y2M A;  1TJW A;  3R6Q A;  5D6B A;  3CRW 1; 
#chains in the Genus database with same CATH homology
 3KDY A;  1VDK A;  4ADL A;  2O6Y A;  1C3U A;  3BHG A;  5HW2 A;  1C3C A;  2QVE A;  1KQ7 A;  2J91 A;  1YFM A;  2PTQ A;  4V2R A;  2RJS A;  2O7B A;  1TJV A;  1FUO A;  1U16 A;  4BAB A;  1T6P A;  4EEI A;  2O7D A;  1I0A A;  4NLE A;  1XWO A;  3UNV A;  2O78 A;  1K62 A;  1FUQ A;  4NSL A;  1GK3 A;  1B8F A;  3TV2 A;  2O7F A;  1K7W A;  1EB4 A;  2RJR A;  2PTS A;  4BAA A;  3RD8 A;  4FFX A;  2X75 A;  1DOF A;  1AUW A;  1GKM A;  1JSW A;  1RE5 A;  2NYN A;  4HGV A;  4C5R A;  1T6J A;  1J3U A;  3QBP A;  1HY0 A;  4V2Q A;  2E9F A;  2OHY A;  3GTD A;  1GKJ A;  1YIS A;  1U15 A;  1FUR A;  4C5U A;  3C8T A;  3R6Y A;  4FLC A;  2YII A;  3RRP A;  4MX2 A;  4EFC A;  3CZO A;  1FUP A;  5F91 A;  1W27 A;  2QGA B;  1TJ7 A;  2HVG A;  4APA A;  3R6V A;  1YFE A;  2NYF A;  2PFM A;  5F92 A;  5EYT A;  4C6G A;  1GK2 A;  1HY1 A;  3GZH A;  3NZ4 A;  2PTR A;  3NO9 A;  3OCF A;  4C5S A;  1Q5N A;  5EYV A;  3OCE A;  4CQ5 A;  4APB A;  1TJU A;  2FUS A;  2VD6 A;  3KDZ A;  3E04 A;  1DCN A;  4ADM A;  2O7E A;  1Y2M A;  1TJW A;  3R6Q A;  5D6B A; 
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