5EYTA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in complex with amp
Total Genus 181
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
478
structure length
472
Chain Sequence
b'EFEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNITI'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Lyase
total genus 181
structure length 472
sequence length 478
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eytA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eytA02
2NYFA 3KDZA 4APAA 4C5UA 4FFXA 3R6VA 4C5SA 3R6QA 1TJUA 1C3CA 4CQ5A 1TJVA 1HY1A 5F92A 2HVGA 1YFMA 1YFEA 1DOFA 1I0AA 1TJ7A 1TJWA 3CZOA 1U16A 2PTQA 3KDYA 1JSWA 4FLCA 2NYNA 4NSLA 2O7BA 4HGVA 2FUSA 2RJSA 3TV2A 2PFMA 4V2QA 2J91A 3NZ4A 2O7EA 2OHYA 1RE5A 2QVEA 1FURA 4ADMA 3RD8A 1EB4A 1VDKA 1T6PA 2O6YA 4EFCA 2RJRA 1GK3A 2X75A 2QGAB 3C8TA 1GKJA 4NLEA 4EEIA 3OCEA 4C5RA 4V2RA 1K62A 1B8FA 1Y2MA 3E04A 1T6JA 1XWOA 3OCFA 1FUQA 2PTRA 3GTDA 1K7WA 4BAAA 1HY0A 5HW2A 4ADLA 2PTSA 3RRPA 1YISA 2VD6A 2O7FA 3GZHA 1GK2A 1AUWA 4MX2A 1W27A 1U15A 1C3UA 2O78A 5EYVA 3BHGA 3R6YA 4APBA 1Q5NA 5F91A 2YIIA 1J3UA 3NO9A 3QBPA 5D6BA 5EYTA 4BABA 1KQ7A 2O7DA 1FUOA 4C6GA 2E9FA 1DCNA 1FUPA 3UNVA 1GKMA
chains in the Genus database with same CATH superfamily
2NYFA 2VL7A 3KDZA 4APAA 4C5UA 4FFXA 3R6VA 4C5SA 3R6QA 1TJUA 1XLYA 1C3CA 4CQ5A 1XMDA 1TJVA 1HY1A 5F92A 2HVGA 1YFMA 1YFEA 1DOFA 1I0AA 1TJ7A 1TJWA 3CZOA 1U16A 2PTQA 3KDYA 1JSWA 4FLCA 2NYNA 4NSLA 2O7BA 4HGVA 2FUSA 2RJSA 3TV2A 2PFMA 4V2QA 5M0IA 2J91A 3NZ4A 2O7EA 2OHYA 1RE5A 5M0JA 2QVEA 1FURA 2FENA 4ADMA 3RD8A 1EB4A 1VDKA 1T6PA 4WNLA 2O6YA 4EFCA 2RJRA 1GK3A 2X75A 2QGAB 1XL7A 3C8TA 1GKJA 4NLEA 4EEIA 5H8WA 3OCEA 4C5RA 2FELA 4V2RA 1K62A 1B8FA 1Y2MA 3E04A 1T6JA 1XMCA 1XWOA 3OCFA 1FUQA 2PTRA 3GTDA 1K7WA 4BAAA 1HY0A 5HW2A 4ADLA 2PTSA 3RRPA 1YISA 2VSFA 2VD6A 2O7FA 3GZHA 1GK2A 1AUWA 3CRVA 4MX2A 1W27A 1XL8A 1U15A 1C3UA 2O78A 5EYVA 3BHGA 3R6YA 4APBA 4A15A 1Q5NA 5F91A 2YIIA 1J3UA 3NO9A 3QBPA 5D6BA 5EYTA 4BABA 1KQ7A 2O7DA 1FUOA 4C6GA 2E9FA 1DCNA 1FUPA 3UNVA 3CRW1 1GKMA
chains in the Genus database with same CATH topology
2NYFA 3KDZA 4APAA 4C5UA 4FFXA 3R6VA 4C5SA 3R6QA 1TJUA 1C3CA 4CQ5A 1TJVA 1HY1A 5F92A 2HVGA 1YFMA 1YFEA 1DOFA 1I0AA 1TJ7A 1TJWA 3CZOA 1U16A 2PTQA 3KDYA 1JSWA 4FLCA 2NYNA 4NSLA 2O7BA 4HGVA 2FUSA 2RJSA 3TV2A 2PFMA 4V2QA 2J91A 3NZ4A 2O7EA 2OHYA 1RE5A 2QVEA 1FURA 4ADMA 3RD8A 1EB4A 1VDKA 1T6PA 2O6YA 4EFCA 2RJRA 1GK3A 2X75A 2QGAB 3C8TA 1GKJA 4NLEA 4EEIA 3OCEA 4C5RA 4V2RA 1K62A 1B8FA 1Y2MA 3E04A 1T6JA 1XWOA 3OCFA 1FUQA 2PTRA 3GTDA 1K7WA 4BAAA 1HY0A 5HW2A 4ADLA 2PTSA 3RRPA 1YISA 2VD6A 2O7FA 3GZHA 1GK2A 1AUWA 4MX2A 1W27A 1U15A 1C3UA 2O78A 5EYVA 3BHGA 3R6YA 4APBA 1Q5NA 5F91A 2YIIA 1J3UA 3NO9A 3QBPA 5D6BA 5EYTA 4BABA 1KQ7A 2O7DA 1FUOA 4C6GA 2E9FA 1DCNA 1FUPA 3UNVA 1GKMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYF A;  3KDZ A;  4APA A;  4C5U A;  4FFX A;  3R6V A;  4C5S A;  3R6Q A;  1TJU A;  1C3C A;  4CQ5 A;  1TJV A;  1HY1 A;  5F92 A;  2HVG A;  1YFM A;  1YFE A;  1DOF A;  1I0A A;  1TJ7 A;  1TJW A;  3CZO A;  1U16 A;  2PTQ A;  3KDY A;  1JSW A;  4FLC A;  2NYN A;  4NSL A;  2O7B A;  4HGV A;  2FUS A;  2RJS A;  3TV2 A;  2PFM A;  4V2Q A;  2J91 A;  3NZ4 A;  2O7E A;  2OHY A;  1RE5 A;  2QVE A;  1FUR A;  4ADM A;  3RD8 A;  1EB4 A;  1VDK A;  1T6P A;  2O6Y A;  4EFC A;  2RJR A;  1GK3 A;  2X75 A;  2QGA B;  3C8T A;  1GKJ A;  4NLE A;  4EEI A;  3OCE A;  4C5R A;  4V2R A;  1K62 A;  1B8F A;  1Y2M A;  3E04 A;  1T6J A;  1XWO A;  3OCF A;  1FUQ A;  2PTR A;  3GTD A;  1K7W A;  4BAA A;  1HY0 A;  5HW2 A;  4ADL A;  2PTS A;  3RRP A;  1YIS A;  2VD6 A;  2O7F A;  3GZH A;  1GK2 A;  1AUW A;  4MX2 A;  1W27 A;  1U15 A;  1C3U A;  2O78 A;  5EYV A;  3BHG A;  3R6Y A;  4APB A;  1Q5N A;  5F91 A;  2YII A;  1J3U A;  3NO9 A;  3QBP A;  5D6B A;  5EYT A;  4BAB A;  1KQ7 A;  2O7D A;  1FUO A;  4C6G A;  2E9F A;  1DCN A;  1FUP A;  3UNV A;  1GKM A; 
#chains in the Genus database with same CATH topology
 2NYF A;  2VL7 A;  3KDZ A;  4APA A;  4C5U A;  4FFX A;  3R6V A;  4C5S A;  3R6Q A;  1TJU A;  1XLY A;  1C3C A;  4CQ5 A;  1XMD A;  1TJV A;  1HY1 A;  5F92 A;  2HVG A;  1YFM A;  1YFE A;  1DOF A;  1I0A A;  1TJ7 A;  1TJW A;  3CZO A;  1U16 A;  2PTQ A;  3KDY A;  1JSW A;  4FLC A;  2NYN A;  4NSL A;  2O7B A;  4HGV A;  2FUS A;  2RJS A;  3TV2 A;  2PFM A;  4V2Q A;  5M0I A;  2J91 A;  3NZ4 A;  2O7E A;  2OHY A;  1RE5 A;  5M0J A;  2QVE A;  1FUR A;  2FEN A;  4ADM A;  3RD8 A;  1EB4 A;  1VDK A;  1T6P A;  4WNL A;  2O6Y A;  4EFC A;  2RJR A;  1GK3 A;  2X75 A;  2QGA B;  1XL7 A;  3C8T A;  1GKJ A;  4NLE A;  4EEI A;  5H8W A;  3OCE A;  4C5R A;  2FEL A;  4V2R A;  1K62 A;  1B8F A;  1Y2M A;  3E04 A;  1T6J A;  1XMC A;  1XWO A;  3OCF A;  1FUQ A;  2PTR A;  3GTD A;  1K7W A;  4BAA A;  1HY0 A;  5HW2 A;  4ADL A;  2PTS A;  3RRP A;  1YIS A;  2VSF A;  2VD6 A;  2O7F A;  3GZH A;  1GK2 A;  1AUW A;  3CRV A;  4MX2 A;  1W27 A;  1XL8 A;  1U15 A;  1C3U A;  2O78 A;  5EYV A;  3BHG A;  3R6Y A;  4APB A;  4A15 A;  1Q5N A;  5F91 A;  2YII A;  1J3U A;  3NO9 A;  3QBP A;  5D6B A;  5EYT A;  4BAB A;  1KQ7 A;  2O7D A;  1FUO A;  4C6G A;  2E9F A;  1DCN A;  1FUP A;  3UNV A;  3CRW 1;  1GKM A; 
#chains in the Genus database with same CATH homology
 2NYF A;  3KDZ A;  4APA A;  4C5U A;  4FFX A;  3R6V A;  4C5S A;  3R6Q A;  1TJU A;  1C3C A;  4CQ5 A;  1TJV A;  1HY1 A;  5F92 A;  2HVG A;  1YFM A;  1YFE A;  1DOF A;  1I0A A;  1TJ7 A;  1TJW A;  3CZO A;  1U16 A;  2PTQ A;  3KDY A;  1JSW A;  4FLC A;  2NYN A;  4NSL A;  2O7B A;  4HGV A;  2FUS A;  2RJS A;  3TV2 A;  2PFM A;  4V2Q A;  2J91 A;  3NZ4 A;  2O7E A;  2OHY A;  1RE5 A;  2QVE A;  1FUR A;  4ADM A;  3RD8 A;  1EB4 A;  1VDK A;  1T6P A;  2O6Y A;  4EFC A;  2RJR A;  1GK3 A;  2X75 A;  2QGA B;  3C8T A;  1GKJ A;  4NLE A;  4EEI A;  3OCE A;  4C5R A;  4V2R A;  1K62 A;  1B8F A;  1Y2M A;  3E04 A;  1T6J A;  1XWO A;  3OCF A;  1FUQ A;  2PTR A;  3GTD A;  1K7W A;  4BAA A;  1HY0 A;  5HW2 A;  4ADL A;  2PTS A;  3RRP A;  1YIS A;  2VD6 A;  2O7F A;  3GZH A;  1GK2 A;  1AUW A;  4MX2 A;  1W27 A;  1U15 A;  1C3U A;  2O78 A;  5EYV A;  3BHG A;  3R6Y A;  4APB A;  1Q5N A;  5F91 A;  2YII A;  1J3U A;  3NO9 A;  3QBP A;  5D6B A;  5EYT A;  4BAB A;  1KQ7 A;  2O7D A;  1FUO A;  4C6G A;  2E9F A;  1DCN A;  1FUP A;  3UNV A;  1GKM A; 
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