5EYTA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in complex with amp
Total Genus 181
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
181
sequence length
478
structure length
472
Chain Sequence
EFEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNITI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Adenylosuccinate lyase
publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Lyase
total genus 181
structure length 472
sequence length 478
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eytA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eytA02
1J3UA 1YFEA 4BAAA 1Y2MA 3KDZA 3GZHA 1C3CA 4NSLA 2QVEA 3NO9A 1TJ7A 1JSWA 4HGVA 4FFXA 4EEIA 1K62A 1DOFA 1GKJA 2PTRA 4C6GA 1RE5A 2QGAB 4V2RA 3E04A 2X75A 2FUSA 3UNVA 3RRPA 4APBA 2PFMA 1DCNA 3OCFA 2RJRA 4BABA 2PTSA 1TJVA 4NLEA 1K7WA 3TV2A 3RD8A 3OCEA 1B8FA 4ADLA 4CQ5A 1U15A 2O78A 1Q5NA 3KDYA 1GKMA 1T6PA 5F91A 1KQ7A 1YISA 1FURA 4C5SA 1VDKA 1GK2A 1YFMA 1XWOA 4ADMA 3BHGA 2OHYA 3C8TA 2NYNA 1FUPA 2O6YA 5D6BA 2VD6A 1T6JA 5HW2A 2E9FA 2O7DA 4V2QA 3QBPA 5F92A 3CZOA 1I0AA 2O7EA 1FUQA 1W27A 2RJSA 4C5UA 1FUOA 3R6QA 1U16A 2J91A 3R6YA 1HY0A 3GTDA 2PTQA 1GK3A 3NZ4A 4C5RA 5EYTA 4MX2A 2YIIA 1TJUA 1EB4A 2O7BA 1TJWA 2HVGA 1C3UA 1AUWA 4FLCA 3R6VA 2NYFA 4APAA 4EFCA 5EYVA 2O7FA 1HY1A
chains in the Genus database with same CATH superfamily
1J3UA 5M0IA 1YFEA 5H8WA 4BAAA 1Y2MA 3KDZA 3GZHA 1C3CA 4NSLA 4WNLA 2QVEA 3NO9A 2FELA 1TJ7A 1JSWA 4HGVA 4A15A 1XL7A 4FFXA 4EEIA 1K62A 1DOFA 1GKJA 1XLYA 5M0JA 2PTRA 4C6GA 1RE5A 2QGAB 4V2RA 3E04A 2X75A 2FUSA 3UNVA 3RRPA 4APBA 2PFMA 1DCNA 3OCFA 2RJRA 4BABA 2PTSA 1TJVA 4NLEA 1K7WA 3TV2A 3CRVA 3RD8A 3OCEA 1B8FA 4ADLA 4CQ5A 1U15A 2O78A 1Q5NA 3KDYA 1GKMA 1T6PA 5F91A 3CRW1 1KQ7A 1YISA 1FURA 4C5SA 1VDKA 1GK2A 1YFMA 1XWOA 4ADMA 3BHGA 2OHYA 3C8TA 2NYNA 1FUPA 2O6YA 5D6BA 2VD6A 1XMCA 2FENA 1T6JA 5HW2A 2E9FA 2O7DA 4V2QA 3QBPA 2VSFA 5F92A 3CZOA 1I0AA 2O7EA 1FUQA 1W27A 2RJSA 4C5UA 1FUOA 3R6QA 1U16A 2VL7A 1XL8A 2J91A 3R6YA 1HY0A 3GTDA 2PTQA 1GK3A 3NZ4A 4C5RA 5EYTA 4MX2A 2YIIA 1TJUA 1EB4A 2O7BA 1TJWA 2HVGA 1C3UA 1AUWA 4FLCA 3R6VA 2NYFA 4APAA 4EFCA 5EYVA 2O7FA 1HY1A 1XMDA
chains in the Genus database with same CATH topology
1J3UA 1YFEA 4BAAA 1Y2MA 3KDZA 3GZHA 1C3CA 4NSLA 2QVEA 3NO9A 1TJ7A 1JSWA 4HGVA 4FFXA 4EEIA 1K62A 1DOFA 1GKJA 2PTRA 4C6GA 1RE5A 2QGAB 4V2RA 3E04A 2X75A 2FUSA 3UNVA 3RRPA 4APBA 2PFMA 1DCNA 3OCFA 2RJRA 4BABA 2PTSA 1TJVA 4NLEA 1K7WA 3TV2A 3RD8A 3OCEA 1B8FA 4ADLA 4CQ5A 1U15A 2O78A 1Q5NA 3KDYA 1GKMA 1T6PA 5F91A 1KQ7A 1YISA 1FURA 4C5SA 1VDKA 1GK2A 1YFMA 1XWOA 4ADMA 3BHGA 2OHYA 3C8TA 2NYNA 1FUPA 2O6YA 5D6BA 2VD6A 1T6JA 5HW2A 2E9FA 2O7DA 4V2QA 3QBPA 5F92A 3CZOA 1I0AA 2O7EA 1FUQA 1W27A 2RJSA 4C5UA 1FUOA 3R6QA 1U16A 2J91A 3R6YA 1HY0A 3GTDA 2PTQA 1GK3A 3NZ4A 4C5RA 5EYTA 4MX2A 2YIIA 1TJUA 1EB4A 2O7BA 1TJWA 2HVGA 1C3UA 1AUWA 4FLCA 3R6VA 2NYFA 4APAA 4EFCA 5EYVA 2O7FA 1HY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J3U A;  1YFE A;  4BAA A;  1Y2M A;  3KDZ A;  3GZH A;  1C3C A;  4NSL A;  2QVE A;  3NO9 A;  1TJ7 A;  1JSW A;  4HGV A;  4FFX A;  4EEI A;  1K62 A;  1DOF A;  1GKJ A;  2PTR A;  4C6G A;  1RE5 A;  2QGA B;  4V2R A;  3E04 A;  2X75 A;  2FUS A;  3UNV A;  3RRP A;  4APB A;  2PFM A;  1DCN A;  3OCF A;  2RJR A;  4BAB A;  2PTS A;  1TJV A;  4NLE A;  1K7W A;  3TV2 A;  3RD8 A;  3OCE A;  1B8F A;  4ADL A;  4CQ5 A;  1U15 A;  2O78 A;  1Q5N A;  3KDY A;  1GKM A;  1T6P A;  5F91 A;  1KQ7 A;  1YIS A;  1FUR A;  4C5S A;  1VDK A;  1GK2 A;  1YFM A;  1XWO A;  4ADM A;  3BHG A;  2OHY A;  3C8T A;  2NYN A;  1FUP A;  2O6Y A;  5D6B A;  2VD6 A;  1T6J A;  5HW2 A;  2E9F A;  2O7D A;  4V2Q A;  3QBP A;  5F92 A;  3CZO A;  1I0A A;  2O7E A;  1FUQ A;  1W27 A;  2RJS A;  4C5U A;  1FUO A;  3R6Q A;  1U16 A;  2J91 A;  3R6Y A;  1HY0 A;  3GTD A;  2PTQ A;  1GK3 A;  3NZ4 A;  4C5R A;  5EYT A;  4MX2 A;  2YII A;  1TJU A;  1EB4 A;  2O7B A;  1TJW A;  2HVG A;  1C3U A;  1AUW A;  4FLC A;  3R6V A;  2NYF A;  4APA A;  4EFC A;  5EYV A;  2O7F A;  1HY1 A; 
#chains in the Genus database with same CATH topology
 1J3U A;  5M0I A;  1YFE A;  5H8W A;  4BAA A;  1Y2M A;  3KDZ A;  3GZH A;  1C3C A;  4NSL A;  4WNL A;  2QVE A;  3NO9 A;  2FEL A;  1TJ7 A;  1JSW A;  4HGV A;  4A15 A;  1XL7 A;  4FFX A;  4EEI A;  1K62 A;  1DOF A;  1GKJ A;  1XLY A;  5M0J A;  2PTR A;  4C6G A;  1RE5 A;  2QGA B;  4V2R A;  3E04 A;  2X75 A;  2FUS A;  3UNV A;  3RRP A;  4APB A;  2PFM A;  1DCN A;  3OCF A;  2RJR A;  4BAB A;  2PTS A;  1TJV A;  4NLE A;  1K7W A;  3TV2 A;  3CRV A;  3RD8 A;  3OCE A;  1B8F A;  4ADL A;  4CQ5 A;  1U15 A;  2O78 A;  1Q5N A;  3KDY A;  1GKM A;  1T6P A;  5F91 A;  3CRW 1;  1KQ7 A;  1YIS A;  1FUR A;  4C5S A;  1VDK A;  1GK2 A;  1YFM A;  1XWO A;  4ADM A;  3BHG A;  2OHY A;  3C8T A;  2NYN A;  1FUP A;  2O6Y A;  5D6B A;  2VD6 A;  1XMC A;  2FEN A;  1T6J A;  5HW2 A;  2E9F A;  2O7D A;  4V2Q A;  3QBP A;  2VSF A;  5F92 A;  3CZO A;  1I0A A;  2O7E A;  1FUQ A;  1W27 A;  2RJS A;  4C5U A;  1FUO A;  3R6Q A;  1U16 A;  2VL7 A;  1XL8 A;  2J91 A;  3R6Y A;  1HY0 A;  3GTD A;  2PTQ A;  1GK3 A;  3NZ4 A;  4C5R A;  5EYT A;  4MX2 A;  2YII A;  1TJU A;  1EB4 A;  2O7B A;  1TJW A;  2HVG A;  1C3U A;  1AUW A;  4FLC A;  3R6V A;  2NYF A;  4APA A;  4EFC A;  5EYV A;  2O7F A;  1HY1 A;  1XMD A; 
#chains in the Genus database with same CATH homology
 1J3U A;  1YFE A;  4BAA A;  1Y2M A;  3KDZ A;  3GZH A;  1C3C A;  4NSL A;  2QVE A;  3NO9 A;  1TJ7 A;  1JSW A;  4HGV A;  4FFX A;  4EEI A;  1K62 A;  1DOF A;  1GKJ A;  2PTR A;  4C6G A;  1RE5 A;  2QGA B;  4V2R A;  3E04 A;  2X75 A;  2FUS A;  3UNV A;  3RRP A;  4APB A;  2PFM A;  1DCN A;  3OCF A;  2RJR A;  4BAB A;  2PTS A;  1TJV A;  4NLE A;  1K7W A;  3TV2 A;  3RD8 A;  3OCE A;  1B8F A;  4ADL A;  4CQ5 A;  1U15 A;  2O78 A;  1Q5N A;  3KDY A;  1GKM A;  1T6P A;  5F91 A;  1KQ7 A;  1YIS A;  1FUR A;  4C5S A;  1VDK A;  1GK2 A;  1YFM A;  1XWO A;  4ADM A;  3BHG A;  2OHY A;  3C8T A;  2NYN A;  1FUP A;  2O6Y A;  5D6B A;  2VD6 A;  1T6J A;  5HW2 A;  2E9F A;  2O7D A;  4V2Q A;  3QBP A;  5F92 A;  3CZO A;  1I0A A;  2O7E A;  1FUQ A;  1W27 A;  2RJS A;  4C5U A;  1FUO A;  3R6Q A;  1U16 A;  2J91 A;  3R6Y A;  1HY0 A;  3GTD A;  2PTQ A;  1GK3 A;  3NZ4 A;  4C5R A;  5EYT A;  4MX2 A;  2YII A;  1TJU A;  1EB4 A;  2O7B A;  1TJW A;  2HVG A;  1C3U A;  1AUW A;  4FLC A;  3R6V A;  2NYF A;  4APA A;  4EFC A;  5EYV A;  2O7F A;  1HY1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...