5EYVA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in apo form.
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
476
structure length
466
Chain Sequence
FEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNIT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Lyase
molecule keywords Adenylosuccinate lyase
total genus 170
structure length 466
sequence length 476
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eyvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eyvA02
1W27A 1HY1A 1JSWA 1YFEA 2J91A 3C8TA 1XWOA 3OCFA 4EFCA 2RJSA 3GZHA 3GTDA 2PTRA 4HGVA 4C5SA 5HW2A 1DCNA 1K62A 2QVEA 5EYTA 2YIIA 2X75A 1FURA 3KDYA 4CQ5A 4V2QA 2PTSA 2PTQA 4V2RA 1FUPA 1HY0A 1Y2MA 1EB4A 2O7FA 2O7EA 1FUQA 3NO9A 3R6QA 4EEIA 3NZ4A 4APAA 2PFMA 1KQ7A 1YISA 2O78A 2NYFA 2NYNA 1I0AA 2FUSA 3OCEA 4ADLA 4C5RA 2QGAB 1B8FA 3TV2A 1C3UA 1TJUA 1GK3A 4MX2A 2HVGA 1TJ7A 5EYVA 1U15A 2VD6A 3CZOA 1YFMA 3E04A 3RD8A 3QBPA 4C5UA 4BAAA 4C6GA 1C3CA 1TJWA 1RE5A 3KDZA 4NLEA 3R6VA 1K7WA 4APBA 3R6YA 2O6YA 2OHYA 1T6PA 1GKJA 2O7BA 3RRPA 1Q5NA 1U16A 2RJRA 1AUWA 1J3UA 1T6JA 1GKMA 5F92A 1VDKA 4FLCA 5F91A 1TJVA 4NSLA 4FFXA 1GK2A 1FUOA 4BABA 2O7DA 4ADMA 3BHGA 1DOFA 3UNVA 5D6BA 2E9FA
chains in the Genus database with same CATH superfamily
1W27A 5M0JA 4A15A 1HY1A 1JSWA 1YFEA 2J91A 3C8TA 1XL7A 1XMCA 1XWOA 2FENA 3OCFA 4EFCA 2RJSA 3GZHA 3GTDA 2PTRA 4HGVA 4C5SA 5HW2A 1DCNA 1K62A 2QVEA 5EYTA 2YIIA 5H8WA 2X75A 1FURA 3KDYA 4CQ5A 4V2QA 2PTSA 2VL7A 2PTQA 4V2RA 1FUPA 1HY0A 2VSFA 1Y2MA 1EB4A 2O7FA 2O7EA 1FUQA 3NO9A 3R6QA 4EEIA 1XLYA 3NZ4A 4APAA 2PFMA 1KQ7A 1YISA 2O78A 2NYFA 2NYNA 1I0AA 2FUSA 3OCEA 4ADLA 4C5RA 2QGAB 1B8FA 3TV2A 1C3UA 1TJUA 1GK3A 4MX2A 2HVGA 1TJ7A 5EYVA 1U15A 2VD6A 3CZOA 1XL8A 1YFMA 3E04A 3RD8A 3QBPA 5M0IA 4C5UA 4BAAA 4C6GA 1C3CA 1TJWA 4WNLA 1RE5A 3KDZA 4NLEA 3R6VA 1K7WA 4APBA 3R6YA 2O6YA 2OHYA 1T6PA 1GKJA 2O7BA 3RRPA 1Q5NA 1U16A 2RJRA 1AUWA 1J3UA 1T6JA 1GKMA 5F92A 1VDKA 4FLCA 5F91A 1TJVA 3CRW1 4FFXA 4NSLA 1GK2A 1FUOA 4BABA 2O7DA 4ADMA 3BHGA 3CRVA 1DOFA 3UNVA 5D6BA 2FELA 2E9FA 1XMDA
chains in the Genus database with same CATH topology
1W27A 1HY1A 1JSWA 1YFEA 2J91A 3C8TA 1XWOA 3OCFA 4EFCA 2RJSA 3GZHA 3GTDA 2PTRA 4HGVA 4C5SA 5HW2A 1DCNA 1K62A 2QVEA 5EYTA 2YIIA 2X75A 1FURA 3KDYA 4CQ5A 4V2QA 2PTSA 2PTQA 4V2RA 1FUPA 1HY0A 1Y2MA 1EB4A 2O7FA 2O7EA 1FUQA 3NO9A 3R6QA 4EEIA 3NZ4A 4APAA 2PFMA 1KQ7A 1YISA 2O78A 2NYFA 2NYNA 1I0AA 2FUSA 3OCEA 4ADLA 4C5RA 2QGAB 1B8FA 3TV2A 1C3UA 1TJUA 1GK3A 4MX2A 2HVGA 1TJ7A 5EYVA 1U15A 2VD6A 3CZOA 1YFMA 3E04A 3RD8A 3QBPA 4C5UA 4BAAA 4C6GA 1C3CA 1TJWA 1RE5A 3KDZA 4NLEA 3R6VA 1K7WA 4APBA 3R6YA 2O6YA 2OHYA 1T6PA 1GKJA 2O7BA 3RRPA 1Q5NA 1U16A 2RJRA 1AUWA 1J3UA 1T6JA 1GKMA 5F92A 1VDKA 4FLCA 5F91A 1TJVA 4NSLA 4FFXA 1GK2A 1FUOA 4BABA 2O7DA 4ADMA 3BHGA 1DOFA 3UNVA 5D6BA 2E9FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W27 A;  1HY1 A;  1JSW A;  1YFE A;  2J91 A;  3C8T A;  1XWO A;  3OCF A;  4EFC A;  2RJS A;  3GZH A;  3GTD A;  2PTR A;  4HGV A;  4C5S A;  5HW2 A;  1DCN A;  1K62 A;  2QVE A;  5EYT A;  2YII A;  2X75 A;  1FUR A;  3KDY A;  4CQ5 A;  4V2Q A;  2PTS A;  2PTQ A;  4V2R A;  1FUP A;  1HY0 A;  1Y2M A;  1EB4 A;  2O7F A;  2O7E A;  1FUQ A;  3NO9 A;  3R6Q A;  4EEI A;  3NZ4 A;  4APA A;  2PFM A;  1KQ7 A;  1YIS A;  2O78 A;  2NYF A;  2NYN A;  1I0A A;  2FUS A;  3OCE A;  4ADL A;  4C5R A;  2QGA B;  1B8F A;  3TV2 A;  1C3U A;  1TJU A;  1GK3 A;  4MX2 A;  2HVG A;  1TJ7 A;  5EYV A;  1U15 A;  2VD6 A;  3CZO A;  1YFM A;  3E04 A;  3RD8 A;  3QBP A;  4C5U A;  4BAA A;  4C6G A;  1C3C A;  1TJW A;  1RE5 A;  3KDZ A;  4NLE A;  3R6V A;  1K7W A;  4APB A;  3R6Y A;  2O6Y A;  2OHY A;  1T6P A;  1GKJ A;  2O7B A;  3RRP A;  1Q5N A;  1U16 A;  2RJR A;  1AUW A;  1J3U A;  1T6J A;  1GKM A;  5F92 A;  1VDK A;  4FLC A;  5F91 A;  1TJV A;  4NSL A;  4FFX A;  1GK2 A;  1FUO A;  4BAB A;  2O7D A;  4ADM A;  3BHG A;  1DOF A;  3UNV A;  5D6B A;  2E9F A; 
#chains in the Genus database with same CATH topology
 1W27 A;  5M0J A;  4A15 A;  1HY1 A;  1JSW A;  1YFE A;  2J91 A;  3C8T A;  1XL7 A;  1XMC A;  1XWO A;  2FEN A;  3OCF A;  4EFC A;  2RJS A;  3GZH A;  3GTD A;  2PTR A;  4HGV A;  4C5S A;  5HW2 A;  1DCN A;  1K62 A;  2QVE A;  5EYT A;  2YII A;  5H8W A;  2X75 A;  1FUR A;  3KDY A;  4CQ5 A;  4V2Q A;  2PTS A;  2VL7 A;  2PTQ A;  4V2R A;  1FUP A;  1HY0 A;  2VSF A;  1Y2M A;  1EB4 A;  2O7F A;  2O7E A;  1FUQ A;  3NO9 A;  3R6Q A;  4EEI A;  1XLY A;  3NZ4 A;  4APA A;  2PFM A;  1KQ7 A;  1YIS A;  2O78 A;  2NYF A;  2NYN A;  1I0A A;  2FUS A;  3OCE A;  4ADL A;  4C5R A;  2QGA B;  1B8F A;  3TV2 A;  1C3U A;  1TJU A;  1GK3 A;  4MX2 A;  2HVG A;  1TJ7 A;  5EYV A;  1U15 A;  2VD6 A;  3CZO A;  1XL8 A;  1YFM A;  3E04 A;  3RD8 A;  3QBP A;  5M0I A;  4C5U A;  4BAA A;  4C6G A;  1C3C A;  1TJW A;  4WNL A;  1RE5 A;  3KDZ A;  4NLE A;  3R6V A;  1K7W A;  4APB A;  3R6Y A;  2O6Y A;  2OHY A;  1T6P A;  1GKJ A;  2O7B A;  3RRP A;  1Q5N A;  1U16 A;  2RJR A;  1AUW A;  1J3U A;  1T6J A;  1GKM A;  5F92 A;  1VDK A;  4FLC A;  5F91 A;  1TJV A;  3CRW 1;  4FFX A;  4NSL A;  1GK2 A;  1FUO A;  4BAB A;  2O7D A;  4ADM A;  3BHG A;  3CRV A;  1DOF A;  3UNV A;  5D6B A;  2FEL A;  2E9F A;  1XMD A; 
#chains in the Genus database with same CATH homology
 1W27 A;  1HY1 A;  1JSW A;  1YFE A;  2J91 A;  3C8T A;  1XWO A;  3OCF A;  4EFC A;  2RJS A;  3GZH A;  3GTD A;  2PTR A;  4HGV A;  4C5S A;  5HW2 A;  1DCN A;  1K62 A;  2QVE A;  5EYT A;  2YII A;  2X75 A;  1FUR A;  3KDY A;  4CQ5 A;  4V2Q A;  2PTS A;  2PTQ A;  4V2R A;  1FUP A;  1HY0 A;  1Y2M A;  1EB4 A;  2O7F A;  2O7E A;  1FUQ A;  3NO9 A;  3R6Q A;  4EEI A;  3NZ4 A;  4APA A;  2PFM A;  1KQ7 A;  1YIS A;  2O78 A;  2NYF A;  2NYN A;  1I0A A;  2FUS A;  3OCE A;  4ADL A;  4C5R A;  2QGA B;  1B8F A;  3TV2 A;  1C3U A;  1TJU A;  1GK3 A;  4MX2 A;  2HVG A;  1TJ7 A;  5EYV A;  1U15 A;  2VD6 A;  3CZO A;  1YFM A;  3E04 A;  3RD8 A;  3QBP A;  4C5U A;  4BAA A;  4C6G A;  1C3C A;  1TJW A;  1RE5 A;  3KDZ A;  4NLE A;  3R6V A;  1K7W A;  4APB A;  3R6Y A;  2O6Y A;  2OHY A;  1T6P A;  1GKJ A;  2O7B A;  3RRP A;  1Q5N A;  1U16 A;  2RJR A;  1AUW A;  1J3U A;  1T6J A;  1GKM A;  5F92 A;  1VDK A;  4FLC A;  5F91 A;  1TJV A;  4NSL A;  4FFX A;  1GK2 A;  1FUO A;  4BAB A;  2O7D A;  4ADM A;  3BHG A;  1DOF A;  3UNV A;  5D6B A;  2E9F A; 
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