5EYVA

Crystal structure of adenylosuccinate lyase from schistosoma mansoni in apo form.
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
476
structure length
466
Chain Sequence
b'FEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNIT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Lyase
total genus 170
structure length 466
sequence length 476
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2015-11-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10397 ADSL_C Adenylosuccinate lyase C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 5eyvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 5eyvA02
1KQ7A 2VD6A 2O7DA 3OCEA 2PTRA 5F91A 3OCFA 4HGVA 5EYVA 1JSWA 4NSLA 1C3CA 1TJ7A 2QVEA 1EB4A 4ADMA 4BABA 4FFXA 1DCNA 1VDKA 4C5SA 4CQ5A 1FUPA 1B8FA 2NYFA 1Y2MA 4EEIA 2X75A 1FUOA 1GK2A 1Q5NA 2O7FA 1RE5A 3RD8A 1YISA 1HY0A 2FUSA 1HY1A 3KDZA 4FLCA 1DOFA 2NYNA 1GKJA 3RRPA 2O7EA 2O6YA 3GZHA 1FUQA 3R6QA 1FURA 1K7WA 3E04A 4ADLA 2E9FA 4NLEA 1GKMA 1T6JA 1TJVA 2RJSA 3CZOA 4APAA 2PTSA 1XWOA 1TJWA 1W27A 2O78A 3NZ4A 1AUWA 3GTDA 4V2RA 3BHGA 1TJUA 4C5UA 4V2QA 4APBA 5D6BA 3R6YA 2HVGA 4C6GA 1J3UA 1U15A 4MX2A 1U16A 2YIIA 5EYTA 3UNVA 1C3UA 3NO9A 1GK3A 2OHYA 3R6VA 2O7BA 2RJRA 4C5RA 1I0AA 3TV2A 2PTQA 5HW2A 3QBPA 4EFCA 4BAAA 1T6PA 1K62A 2QGAB 3KDYA 2J91A 1YFEA 2PFMA 3C8TA 5F92A 1YFMA
chains in the Genus database with same CATH superfamily
1KQ7A 2VD6A 2O7DA 3CRVA 2VL7A 3OCEA 2PTRA 5F91A 3OCFA 4HGVA 5EYVA 1JSWA 4A15A 4NSLA 1C3CA 1TJ7A 2QVEA 1XMCA 3CRW1 1EB4A 4ADMA 1XMDA 4BABA 4FFXA 1DCNA 1VDKA 4C5SA 4CQ5A 1FUPA 2FENA 5M0JA 1B8FA 2VSFA 2NYFA 1Y2MA 4EEIA 2X75A 1FUOA 1GK2A 1Q5NA 2O7FA 1RE5A 3RD8A 1YISA 2FELA 1HY0A 2FUSA 1HY1A 3KDZA 4FLCA 1DOFA 1XL8A 2NYNA 1GKJA 3RRPA 2O7EA 2O6YA 3GZHA 1FUQA 3R6QA 1FURA 1K7WA 3E04A 2E9FA 4ADLA 4WNLA 4NLEA 1GKMA 1T6JA 1TJVA 2RJSA 3CZOA 4APAA 2PTSA 1XWOA 1TJWA 1W27A 2O78A 3NZ4A 1AUWA 3GTDA 4V2RA 3BHGA 1TJUA 4C5UA 4V2QA 4APBA 5D6BA 3R6YA 2HVGA 4C6GA 1J3UA 1U15A 4MX2A 1U16A 2YIIA 5EYTA 3UNVA 1C3UA 3NO9A 1GK3A 2OHYA 3R6VA 2O7BA 5M0IA 2RJRA 4C5RA 1I0AA 5H8WA 3TV2A 2PTQA 5HW2A 3QBPA 4EFCA 4BAAA 1T6PA 1K62A 2QGAB 3KDYA 2J91A 1XL7A 1YFEA 2PFMA 1XLYA 3C8TA 5F92A 1YFMA
chains in the Genus database with same CATH topology
1KQ7A 2VD6A 2O7DA 3OCEA 2PTRA 5F91A 3OCFA 4HGVA 5EYVA 1JSWA 4NSLA 1C3CA 1TJ7A 2QVEA 1EB4A 4ADMA 4BABA 4FFXA 1DCNA 1VDKA 4C5SA 4CQ5A 1FUPA 1B8FA 2NYFA 1Y2MA 4EEIA 2X75A 1FUOA 1GK2A 1Q5NA 2O7FA 1RE5A 3RD8A 1YISA 1HY0A 2FUSA 1HY1A 3KDZA 4FLCA 1DOFA 2NYNA 1GKJA 3RRPA 2O7EA 2O6YA 3GZHA 1FUQA 3R6QA 1FURA 1K7WA 3E04A 4ADLA 2E9FA 4NLEA 1GKMA 1T6JA 1TJVA 2RJSA 3CZOA 4APAA 2PTSA 1XWOA 1TJWA 1W27A 2O78A 3NZ4A 1AUWA 3GTDA 4V2RA 3BHGA 1TJUA 4C5UA 4V2QA 4APBA 5D6BA 3R6YA 2HVGA 4C6GA 1J3UA 1U15A 4MX2A 1U16A 2YIIA 5EYTA 3UNVA 1C3UA 3NO9A 1GK3A 2OHYA 3R6VA 2O7BA 2RJRA 4C5RA 1I0AA 3TV2A 2PTQA 5HW2A 3QBPA 4EFCA 4BAAA 1T6PA 1K62A 2QGAB 3KDYA 2J91A 1YFEA 2PFMA 3C8TA 5F92A 1YFMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KQ7 A;  2VD6 A;  2O7D A;  3OCE A;  2PTR A;  5F91 A;  3OCF A;  4HGV A;  5EYV A;  1JSW A;  4NSL A;  1C3C A;  1TJ7 A;  2QVE A;  1EB4 A;  4ADM A;  4BAB A;  4FFX A;  1DCN A;  1VDK A;  4C5S A;  4CQ5 A;  1FUP A;  1B8F A;  2NYF A;  1Y2M A;  4EEI A;  2X75 A;  1FUO A;  1GK2 A;  1Q5N A;  2O7F A;  1RE5 A;  3RD8 A;  1YIS A;  1HY0 A;  2FUS A;  1HY1 A;  3KDZ A;  4FLC A;  1DOF A;  2NYN A;  1GKJ A;  3RRP A;  2O7E A;  2O6Y A;  3GZH A;  1FUQ A;  3R6Q A;  1FUR A;  1K7W A;  3E04 A;  4ADL A;  2E9F A;  4NLE A;  1GKM A;  1T6J A;  1TJV A;  2RJS A;  3CZO A;  4APA A;  2PTS A;  1XWO A;  1TJW A;  1W27 A;  2O78 A;  3NZ4 A;  1AUW A;  3GTD A;  4V2R A;  3BHG A;  1TJU A;  4C5U A;  4V2Q A;  4APB A;  5D6B A;  3R6Y A;  2HVG A;  4C6G A;  1J3U A;  1U15 A;  4MX2 A;  1U16 A;  2YII A;  5EYT A;  3UNV A;  1C3U A;  3NO9 A;  1GK3 A;  2OHY A;  3R6V A;  2O7B A;  2RJR A;  4C5R A;  1I0A A;  3TV2 A;  2PTQ A;  5HW2 A;  3QBP A;  4EFC A;  4BAA A;  1T6P A;  1K62 A;  2QGA B;  3KDY A;  2J91 A;  1YFE A;  2PFM A;  3C8T A;  5F92 A;  1YFM A; 
#chains in the Genus database with same CATH topology
 1KQ7 A;  2VD6 A;  2O7D A;  3CRV A;  2VL7 A;  3OCE A;  2PTR A;  5F91 A;  3OCF A;  4HGV A;  5EYV A;  1JSW A;  4A15 A;  4NSL A;  1C3C A;  1TJ7 A;  2QVE A;  1XMC A;  3CRW 1;  1EB4 A;  4ADM A;  1XMD A;  4BAB A;  4FFX A;  1DCN A;  1VDK A;  4C5S A;  4CQ5 A;  1FUP A;  2FEN A;  5M0J A;  1B8F A;  2VSF A;  2NYF A;  1Y2M A;  4EEI A;  2X75 A;  1FUO A;  1GK2 A;  1Q5N A;  2O7F A;  1RE5 A;  3RD8 A;  1YIS A;  2FEL A;  1HY0 A;  2FUS A;  1HY1 A;  3KDZ A;  4FLC A;  1DOF A;  1XL8 A;  2NYN A;  1GKJ A;  3RRP A;  2O7E A;  2O6Y A;  3GZH A;  1FUQ A;  3R6Q A;  1FUR A;  1K7W A;  3E04 A;  2E9F A;  4ADL A;  4WNL A;  4NLE A;  1GKM A;  1T6J A;  1TJV A;  2RJS A;  3CZO A;  4APA A;  2PTS A;  1XWO A;  1TJW A;  1W27 A;  2O78 A;  3NZ4 A;  1AUW A;  3GTD A;  4V2R A;  3BHG A;  1TJU A;  4C5U A;  4V2Q A;  4APB A;  5D6B A;  3R6Y A;  2HVG A;  4C6G A;  1J3U A;  1U15 A;  4MX2 A;  1U16 A;  2YII A;  5EYT A;  3UNV A;  1C3U A;  3NO9 A;  1GK3 A;  2OHY A;  3R6V A;  2O7B A;  5M0I A;  2RJR A;  4C5R A;  1I0A A;  5H8W A;  3TV2 A;  2PTQ A;  5HW2 A;  3QBP A;  4EFC A;  4BAA A;  1T6P A;  1K62 A;  2QGA B;  3KDY A;  2J91 A;  1XL7 A;  1YFE A;  2PFM A;  1XLY A;  3C8T A;  5F92 A;  1YFM A; 
#chains in the Genus database with same CATH homology
 1KQ7 A;  2VD6 A;  2O7D A;  3OCE A;  2PTR A;  5F91 A;  3OCF A;  4HGV A;  5EYV A;  1JSW A;  4NSL A;  1C3C A;  1TJ7 A;  2QVE A;  1EB4 A;  4ADM A;  4BAB A;  4FFX A;  1DCN A;  1VDK A;  4C5S A;  4CQ5 A;  1FUP A;  1B8F A;  2NYF A;  1Y2M A;  4EEI A;  2X75 A;  1FUO A;  1GK2 A;  1Q5N A;  2O7F A;  1RE5 A;  3RD8 A;  1YIS A;  1HY0 A;  2FUS A;  1HY1 A;  3KDZ A;  4FLC A;  1DOF A;  2NYN A;  1GKJ A;  3RRP A;  2O7E A;  2O6Y A;  3GZH A;  1FUQ A;  3R6Q A;  1FUR A;  1K7W A;  3E04 A;  4ADL A;  2E9F A;  4NLE A;  1GKM A;  1T6J A;  1TJV A;  2RJS A;  3CZO A;  4APA A;  2PTS A;  1XWO A;  1TJW A;  1W27 A;  2O78 A;  3NZ4 A;  1AUW A;  3GTD A;  4V2R A;  3BHG A;  1TJU A;  4C5U A;  4V2Q A;  4APB A;  5D6B A;  3R6Y A;  2HVG A;  4C6G A;  1J3U A;  1U15 A;  4MX2 A;  1U16 A;  2YII A;  5EYT A;  3UNV A;  1C3U A;  3NO9 A;  1GK3 A;  2OHY A;  3R6V A;  2O7B A;  2RJR A;  4C5R A;  1I0A A;  3TV2 A;  2PTQ A;  5HW2 A;  3QBP A;  4EFC A;  4BAA A;  1T6P A;  1K62 A;  2QGA B;  3KDY A;  2J91 A;  1YFE A;  2PFM A;  3C8T A;  5F92 A;  1YFM A; 
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