5FSZA

Crystal structure of trypanosoma cruzi macrodomain
Total Genus 81
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
245
structure length
245
Chain Sequence
FVTYSTSEPAKLFGEAGRRSHFRARVLEATLSPLEKAIFDVPIEEWLTVDRSKFSGWRCAVPHPVTADELKPVDSSHDILRHIALYNGPVTDLQLDAIVNAANKTCLGGKGVDGAIHAAAGPLLVRECATFKGCDTGQCRLTKGYNLPARYVLHTVGPIGERPEELRSCYRSILSLAHRNRLRSIGFCCVSTGVYGYPLIPATRIAVDETIEYLKQHFSAFDLCCFACFKLEEYNAYTDCLRAWL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Proximal Adp-Ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain.
pubmed doi rcsb
molecule keywords MACRODOMAIN
molecule tags Hydrolase
source organism Trypanosoma cruzi
total genus 81
structure length 245
sequence length 245
ec nomenclature
pdb deposition date 2016-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5fszA00
2L8RA 3GQEA 3GPOA 5HIHA 1LAMA 4D86A 3Q6ZA 3H8GA 4JGKA 1TXZA 3JZTA 5AILA 4ZYQA 4ZY2A 2LGRA 2XD7A 1BLLE 3SIIA 1ZR3A 4K3NA 1TY8A 3GQOA 3H8EA 2DX6A 3EJGA 3ETIA 4TU0A 2X47A 4ZY1A 4J4ZA 3EKEA 3IIDA 3EWPA 4J5QA 1GYTA 3SIJA 4JLLA 4IQYA 3GPGA 1LAPA 1YD9A 4ZI6A 3V45A 4GUAA 4J5SA 5FSXA 5E3BA 3SIGA 2FXKA 2VRIA 5FSZA 3JRUA 4X2TA 1BPNA 4KYBA 1LCPA 2ACFA 1NJRA 3EJFA 3EWQA 2AFCA 4KSIA 5FSVA 4R76A 5CMSA 5CB5A 5FSUA 3V2BA 4K0CA 5CBMA 1BPMA 2BFQA 4ABLA 4JVVA 4GVVA 5FSYA 3PEIA 4ZX8A 3KQXA 3EWRA 4ESSA 3GPQA 3IIFA 3KR4A 3SIHA 2FG1A 3KQZA 4ZX9A 1HJZA 3KZWA 3IJ3A 2J9AA 5D8NA 1VHUA 1SPVA 4ETKA 4R6TA 3H8FA 4UMLA 3Q71A 4JCAA 2EEEA 3EW5A 4J5RA 4ETJA 3T8WA 5CB3A 5DUSA 2EWBA 4R7MA 4ABKA 1ZR5A 5HOLA 1LANA 3VFQA 3KR5A 4ZY0A 2FAVA 4GVWA 3EWOA 2BFRA
chains in the Genus database with same CATH superfamily
2L8RA 3GQEA 3GPOA 5HIHA 1LAMA 4D86A 3Q6ZA 3H8GA 4JGKA 1TXZA 3JZTA 5AILA 4ZYQA 4ZY2A 2LGRA 2XD7A 1BLLE 3SIIA 1ZR3A 4K3NA 1TY8A 3GQOA 3H8EA 2DX6A 3EJGA 3ETIA 4TU0A 2X47A 4ZY1A 4J4ZA 3EKEA 3IIDA 3EWPA 4J5QA 1GYTA 3SIJA 4JLLA 4IQYA 3GPGA 1LAPA 1YD9A 4ZI6A 3V45A 4GUAA 4J5SA 5FSXA 2WCTA 5E3BA 3SIGA 2FXKA 2VRIA 5FSZA 3JRUA 4X2TA 1BPNA 4KYBA 1LCPA 2ACFA 1NJRA 3EJFA 2JZFA 3EWQA 2KQVA 2RNKA 2AFCA 4KSIA 5FSVA 4R76A 5CMSA 5CB5A 5FSUA 3V2BA 4K0CA 5CBMA 1BPMA 2BFQA 4ABLA 2JZDA 4JVVA 4GVVA 5FSYA 2JZEA 3PEIA 3KQXA 4ZX8A 3EWRA 4ESSA 2W2GA 3GPQA 3IIFA 3KR4A 3SIHA 2FG1A 3KQZA 4ZX9A 1HJZA 3KZWA 3IJ3A 2J9AA 5D8NA 1VHUA 1SPVA 4ETKA 4R6TA 3H8FA 4UMLA 3Q71A 4JCAA 2EEEA 3EW5A 4J5RA 4ETJA 3T8WA 5CB3A 5DUSA 2EWBA 4R7MA 4ABKA 1ZR5A 5HOLA 1LANA 3VFQA 3KR5A 4ZY0A 2FAVA 4GVWA 3EWOA 2BFRA
chains in the Genus database with same CATH topology
2L8RA 3GQEA 3GPOA 5HIHA 1LAMA 4D86A 3Q6ZA 3H8GA 4JGKA 1TXZA 3JZTA 5AILA 4ZYQA 4ZY2A 2LGRA 2XD7A 1BLLE 3SIIA 1ZR3A 4K3NA 1TY8A 3GQOA 3H8EA 2DX6A 3EJGA 3ETIA 4TU0A 2X47A 4ZY1A 4J4ZA 3EKEA 3IIDA 3EWPA 4J5QA 1GYTA 3SIJA 4JLLA 4IQYA 3GPGA 1LAPA 1YD9A 4ZI6A 3V45A 4GUAA 4J5SA 5FSXA 5E3BA 3SIGA 2FXKA 2VRIA 5FSZA 3JRUA 4X2TA 1BPNA 4KYBA 1LCPA 2ACFA 1NJRA 3EJFA 3EWQA 2AFCA 4KSIA 5FSVA 4R76A 5CMSA 5CB5A 5FSUA 3V2BA 4K0CA 5CBMA 1BPMA 2BFQA 4ABLA 4JVVA 4GVVA 5FSYA 3PEIA 4ZX8A 3KQXA 3EWRA 4ESSA 3GPQA 3IIFA 3KR4A 3SIHA 2FG1A 3KQZA 4ZX9A 1HJZA 3KZWA 3IJ3A 2J9AA 5D8NA 1VHUA 1SPVA 4ETKA 4R6TA 3H8FA 4UMLA 3Q71A 4JCAA 2EEEA 3EW5A 4J5RA 4ETJA 3T8WA 5CB3A 5DUSA 2EWBA 4R7MA 4ABKA 1ZR5A 5HOLA 1LANA 3VFQA 3KR5A 4ZY0A 2FAVA 4GVWA 3EWOA 2BFRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L8R A;  3GQE A;  3GPO A;  5HIH A;  1LAM A;  4D86 A;  3Q6Z A;  3H8G A;  4JGK A;  1TXZ A;  3JZT A;  5AIL A;  4ZYQ A;  4ZY2 A;  2LGR A;  2XD7 A;  1BLL E;  3SII A;  1ZR3 A;  4K3N A;  1TY8 A;  3GQO A;  3H8E A;  2DX6 A;  3EJG A;  3ETI A;  4TU0 A;  2X47 A;  4ZY1 A;  4J4Z A;  3EKE A;  3IID A;  3EWP A;  4J5Q A;  1GYT A;  3SIJ A;  4JLL A;  4IQY A;  3GPG A;  1LAP A;  1YD9 A;  4ZI6 A;  3V45 A;  4GUA A;  4J5S A;  5FSX A;  5E3B A;  3SIG A;  2FXK A;  2VRI A;  5FSZ A;  3JRU A;  4X2T A;  1BPN A;  4KYB A;  1LCP A;  2ACF A;  1NJR A;  3EJF A;  3EWQ A;  2AFC A;  4KSI A;  5FSV A;  4R76 A;  5CMS A;  5CB5 A;  5FSU A;  3V2B A;  4K0C A;  5CBM A;  1BPM A;  2BFQ A;  4ABL A;  4JVV A;  4GVV A;  5FSY A;  3PEI A;  4ZX8 A;  3KQX A;  3EWR A;  4ESS A;  3GPQ A;  3IIF A;  3KR4 A;  3SIH A;  2FG1 A;  3KQZ A;  4ZX9 A;  1HJZ A;  3KZW A;  3IJ3 A;  2J9A A;  5D8N A;  1VHU A;  1SPV A;  4ETK A;  4R6T A;  3H8F A;  4UML A;  3Q71 A;  4JCA A;  2EEE A;  3EW5 A;  4J5R A;  4ETJ A;  3T8W A;  5CB3 A;  5DUS A;  2EWB A;  4R7M A;  4ABK A;  1ZR5 A;  5HOL A;  1LAN A;  3VFQ A;  3KR5 A;  4ZY0 A;  2FAV A;  4GVW A;  3EWO A;  2BFR A; 
#chains in the Genus database with same CATH topology
 2L8R A;  3GQE A;  3GPO A;  5HIH A;  1LAM A;  4D86 A;  3Q6Z A;  3H8G A;  4JGK A;  1TXZ A;  3JZT A;  5AIL A;  4ZYQ A;  4ZY2 A;  2LGR A;  2XD7 A;  1BLL E;  3SII A;  1ZR3 A;  4K3N A;  1TY8 A;  3GQO A;  3H8E A;  2DX6 A;  3EJG A;  3ETI A;  4TU0 A;  2X47 A;  4ZY1 A;  4J4Z A;  3EKE A;  3IID A;  3EWP A;  4J5Q A;  1GYT A;  3SIJ A;  4JLL A;  4IQY A;  3GPG A;  1LAP A;  1YD9 A;  4ZI6 A;  3V45 A;  4GUA A;  4J5S A;  5FSX A;  2WCT A;  5E3B A;  3SIG A;  2FXK A;  2VRI A;  5FSZ A;  3JRU A;  4X2T A;  1BPN A;  4KYB A;  1LCP A;  2ACF A;  1NJR A;  3EJF A;  2JZF A;  3EWQ A;  2KQV A;  2RNK A;  2AFC A;  4KSI A;  5FSV A;  4R76 A;  5CMS A;  5CB5 A;  5FSU A;  3V2B A;  4K0C A;  5CBM A;  1BPM A;  2BFQ A;  4ABL A;  2JZD A;  4JVV A;  4GVV A;  5FSY A;  2JZE A;  3PEI A;  3KQX A;  4ZX8 A;  3EWR A;  4ESS A;  2W2G A;  3GPQ A;  3IIF A;  3KR4 A;  3SIH A;  2FG1 A;  3KQZ A;  4ZX9 A;  1HJZ A;  3KZW A;  3IJ3 A;  2J9A A;  5D8N A;  1VHU A;  1SPV A;  4ETK A;  4R6T A;  3H8F A;  4UML A;  3Q71 A;  4JCA A;  2EEE A;  3EW5 A;  4J5R A;  4ETJ A;  3T8W A;  5CB3 A;  5DUS A;  2EWB A;  4R7M A;  4ABK A;  1ZR5 A;  5HOL A;  1LAN A;  3VFQ A;  3KR5 A;  4ZY0 A;  2FAV A;  4GVW A;  3EWO A;  2BFR A; 
#chains in the Genus database with same CATH homology
 2L8R A;  3GQE A;  3GPO A;  5HIH A;  1LAM A;  4D86 A;  3Q6Z A;  3H8G A;  4JGK A;  1TXZ A;  3JZT A;  5AIL A;  4ZYQ A;  4ZY2 A;  2LGR A;  2XD7 A;  1BLL E;  3SII A;  1ZR3 A;  4K3N A;  1TY8 A;  3GQO A;  3H8E A;  2DX6 A;  3EJG A;  3ETI A;  4TU0 A;  2X47 A;  4ZY1 A;  4J4Z A;  3EKE A;  3IID A;  3EWP A;  4J5Q A;  1GYT A;  3SIJ A;  4JLL A;  4IQY A;  3GPG A;  1LAP A;  1YD9 A;  4ZI6 A;  3V45 A;  4GUA A;  4J5S A;  5FSX A;  5E3B A;  3SIG A;  2FXK A;  2VRI A;  5FSZ A;  3JRU A;  4X2T A;  1BPN A;  4KYB A;  1LCP A;  2ACF A;  1NJR A;  3EJF A;  3EWQ A;  2AFC A;  4KSI A;  5FSV A;  4R76 A;  5CMS A;  5CB5 A;  5FSU A;  3V2B A;  4K0C A;  5CBM A;  1BPM A;  2BFQ A;  4ABL A;  4JVV A;  4GVV A;  5FSY A;  3PEI A;  4ZX8 A;  3KQX A;  3EWR A;  4ESS A;  3GPQ A;  3IIF A;  3KR4 A;  3SIH A;  2FG1 A;  3KQZ A;  4ZX9 A;  1HJZ A;  3KZW A;  3IJ3 A;  2J9A A;  5D8N A;  1VHU A;  1SPV A;  4ETK A;  4R6T A;  3H8F A;  4UML A;  3Q71 A;  4JCA A;  2EEE A;  3EW5 A;  4J5R A;  4ETJ A;  3T8W A;  5CB3 A;  5DUS A;  2EWB A;  4R7M A;  4ABK A;  1ZR5 A;  5HOL A;  1LAN A;  3VFQ A;  3KR5 A;  4ZY0 A;  2FAV A;  4GVW A;  3EWO A;  2BFR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...