5GH0A

Crystal structure of the complex of bovine lactoperoxidase with mercaptoimidazole at 2.3 a resolution
Total Genus 184
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
184
sequence length
595
structure length
594
Chain Sequence
SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLALPFGWTQRKTRNGFRVPLAREVSNKIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSNEHSKTQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPFFRAGFVCPTPPYQSLAREQINAVTSFLDASLVYGSEPLASRLRNLSSPLGLMAVNQEAWDHGLAYLPFNNKKPSPCEFINTTARVPCFLAGDFRASEQILLATAHTLLLREHNRLARELKKLNPHWNGEKLYQEARKILGAFIQIITFRDYLPIVLGSEMQKWIPPYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPWGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLLAKKSKLMNQDKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQTVLKNKILAKKLMDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHITKVPLHAFQANNYPHDFVDCSTVDKLDLSPWASREN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Design of anti-thyroid drugs: Binding studies and structure determination of the complex of lactoperoxidase with 2-mercaptoimidazole at 2.30 angstrom resolution
pubmed doi rcsb
molecule keywords Lactoperoxidase
molecule tags Oxidoreductase
total genus 184
structure length 594
sequence length 595
ec nomenclature ec 1.11.1.7: Peroxidase.
pdb deposition date 2016-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03098 An_peroxidase Animal haem peroxidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 5gh0A00
3N8XA 5IKRA 1CVUA 2GJMA 1HT5A 2E9EA 3GCJA 1U67A 4QJQA 2OYUP 3V6QA 3OGWA 1MHLC 4LJJA 3N8WA 4GM7A 5GH0A 1DNWC 1PGEA 5KIRA 4KVJA 3QMOA 3NTBA 1EBVA 3N8ZA 3ZS0C 2Z5ZA 3ERIA 3QH0A 3NAKA 5IKTA 4M10A 3RR3A 4C1MC 1D5LC 4E1GA 3GCKA 3N8VA 4RUTA 3TGYA 1EQHA 3GCLA 4GN6A 4HHRA 3NT1A 2QQTA 3R5OA 3R5QA 2OJVA 1IGZA 4NJBA 4RRZA 5IKQA 2IPSA 3N8WB 3TZIA 4Y55A 3LN0A 6COXA 5FF1A 2PUMA 5F1AA 3PY4A 3OLUA 3N8YB 3ZS1C 3KK6A 5COXA 4RS0A 3N8YA 5HPWA 1PTHA 4OTJA 2QPKA 1DNUC 2QRBA 2EFBA 3R55A 1D2VC 3Q7DA 1FE2A 2PT3A 3QF1A 3NTGA 4M11A 4PNXA 3ERHA 2EHAA 3PGHA 4KVKA 1CX2A 3KRKA 3UBAA 3R4XA 3FNLA 3BXIA 3SXVA 3HS6A 1HT8A 3NYHA 1Q4GA 1DIYA 2AYLA 4IG5A 4KVLA 2NQXA 5FDQA 3RKEA 4HHSA 3FAQA 1DDXA 4MSFA 4RRWA 2IKCA 4N7AA 3LN1A 5B72A 3MQEA 3QL6A 3NIUA 3I6NA 2OYEP 3S4FA 4DL1C 1PRHA 5FIWC 1CXPC 4QYQA 5JVYA 3MDLA 2R5LA 1PXXA 1EQGA 3HS5A 3F9PC 5JW1A 4RRXA 3N8FA 3OLTA 4PH9A 4COXA 5IKVA 4O1ZA 4KSZA 5JVZA 4NT3A 4OTYA 4OEKA 4Z0LA 4FM5A 1D7WC 1CQEA 4RRYA 3GC1A 1MYPC 1IGXA 3Q9KA 3HS7A 3KRQA 2O86A 5GLSA 5F19A
chains in the Genus database with same CATH superfamily
3N8XA 5IKRA 1CVUA 2GJMA 1HT5A 2E9EA 3GCJA 1U67A 4QJQA 2OYUP 3V6QA 3OGWA 1MHLC 4LJJA 3N8WA 4GM7A 5GH0A 1DNWC 1PGEA 5KIRA 4KVJA 3QMOA 3NTBA 1EBVA 3N8ZA 3ZS0C 2Z5ZA 3ERIA 3QH0A 3NAKA 5IKTA 4M10A 3RR3A 4C1MC 1D5LC 4E1GA 3GCKA 3N8VA 4RUTA 3TGYA 1EQHA 3GCLA 4GN6A 4HHRA 3NT1A 2QQTA 3R5OA 3R5QA 2OJVA 1IGZA 4NJBA 4RRZA 5IKQA 2IPSA 3N8WB 3TZIA 4Y55A 3LN0A 6COXA 5FF1A 2PUMA 5F1AA 3PY4A 3OLUA 3N8YB 3ZS1C 3KK6A 5COXA 4RS0A 3N8YA 5HPWA 1PTHA 4OTJA 2QPKA 1DNUC 2QRBA 2EFBA 3R55A 1D2VC 3Q7DA 1FE2A 2PT3A 3QF1A 3NTGA 4M11A 4PNXA 3ERHA 2EHAA 3PGHA 4KVKA 1CX2A 3KRKA 3UBAA 3R4XA 3FNLA 3BXIA 3SXVA 3HS6A 1HT8A 3NYHA 1Q4GA 1DIYA 2AYLA 4IG5A 4KVLA 2NQXA 5FDQA 3RKEA 4HHSA 3FAQA 1DDXA 4MSFA 4RRWA 2IKCA 4N7AA 3LN1A 5B72A 3MQEA 3QL6A 3NIUA 3I6NA 2OYEP 3S4FA 4DL1C 1PRHA 5FIWC 1CXPC 4QYQA 5JVYA 3MDLA 2R5LA 1PXXA 1EQGA 3HS5A 3F9PC 5JW1A 4RRXA 3N8FA 3OLTA 4PH9A 4COXA 5IKVA 4O1ZA 4KSZA 5JVZA 4NT3A 4OTYA 4OEKA 4Z0LA 4FM5A 1D7WC 1CQEA 4RRYA 3GC1A 1MYPC 1IGXA 3Q9KA 3HS7A 3KRQA 2O86A 5GLSA 5F19A
chains in the Genus database with same CATH topology
3N8XA 5IKRA 1CVUA 2GJMA 1HT5A 2E9EA 3GCJA 1U67A 4QJQA 2OYUP 3V6QA 3OGWA 1MHLC 4LJJA 3N8WA 4GM7A 5GH0A 1DNWC 1PGEA 5KIRA 4KVJA 3QMOA 3NTBA 1EBVA 3N8ZA 3ZS0C 2Z5ZA 3ERIA 3QH0A 3NAKA 5IKTA 4M10A 3RR3A 4C1MC 1D5LC 4E1GA 3GCKA 3N8VA 4RUTA 3TGYA 1EQHA 3GCLA 4GN6A 4HHRA 3NT1A 2QQTA 3R5OA 3R5QA 2OJVA 1IGZA 4NJBA 4RRZA 5IKQA 2IPSA 3N8WB 3TZIA 4Y55A 3LN0A 6COXA 5FF1A 2PUMA 5F1AA 3PY4A 3OLUA 3N8YB 3ZS1C 3KK6A 5COXA 4RS0A 3N8YA 5HPWA 1PTHA 4OTJA 2QPKA 1DNUC 2QRBA 2EFBA 3R55A 1D2VC 3Q7DA 1FE2A 2PT3A 3QF1A 3NTGA 4M11A 4PNXA 3ERHA 2EHAA 3PGHA 4KVKA 1CX2A 3KRKA 3UBAA 3R4XA 3FNLA 3BXIA 3SXVA 3HS6A 1HT8A 3NYHA 1Q4GA 1DIYA 2AYLA 4IG5A 4KVLA 2NQXA 5FDQA 3RKEA 4HHSA 3FAQA 1DDXA 4MSFA 4RRWA 2IKCA 4N7AA 3LN1A 5B72A 3MQEA 3QL6A 3NIUA 3I6NA 2OYEP 3S4FA 4DL1C 1PRHA 5FIWC 1CXPC 4QYQA 5JVYA 3MDLA 2R5LA 1PXXA 1EQGA 3HS5A 3F9PC 5JW1A 4RRXA 3N8FA 3OLTA 4PH9A 4COXA 5IKVA 4O1ZA 4KSZA 5JVZA 4NT3A 4OTYA 4OEKA 4Z0LA 4FM5A 1D7WC 1CQEA 4RRYA 3GC1A 1MYPC 1IGXA 3Q9KA 3HS7A 3KRQA 2O86A 5GLSA 5F19A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3N8X A;  5IKR A;  1CVU A;  2GJM A;  1HT5 A;  2E9E A;  3GCJ A;  1U67 A;  4QJQ A;  2OYU P;  3V6Q A;  3OGW A;  1MHL C;  4LJJ A;  3N8W A;  4GM7 A;  5GH0 A;  1DNW C;  1PGE A;  5KIR A;  4KVJ A;  3QMO A;  3NTB A;  1EBV A;  3N8Z A;  3ZS0 C;  2Z5Z A;  3ERI A;  3QH0 A;  3NAK A;  5IKT A;  4M10 A;  3RR3 A;  4C1M C;  1D5L C;  4E1G A;  3GCK A;  3N8V A;  4RUT A;  3TGY A;  1EQH A;  3GCL A;  4GN6 A;  4HHR A;  3NT1 A;  2QQT A;  3R5O A;  3R5Q A;  2OJV A;  1IGZ A;  4NJB A;  4RRZ A;  5IKQ A;  2IPS A;  3N8W B;  3TZI A;  4Y55 A;  3LN0 A;  6COX A;  5FF1 A;  2PUM A;  5F1A A;  3PY4 A;  3OLU A;  3N8Y B;  3ZS1 C;  3KK6 A;  5COX A;  4RS0 A;  3N8Y A;  5HPW A;  1PTH A;  4OTJ A;  2QPK A;  1DNU C;  2QRB A;  2EFB A;  3R55 A;  1D2V C;  3Q7D A;  1FE2 A;  2PT3 A;  3QF1 A;  3NTG A;  4M11 A;  4PNX A;  3ERH A;  2EHA A;  3PGH A;  4KVK A;  1CX2 A;  3KRK A;  3UBA A;  3R4X A;  3FNL A;  3BXI A;  3SXV A;  3HS6 A;  1HT8 A;  3NYH A;  1Q4G A;  1DIY A;  2AYL A;  4IG5 A;  4KVL A;  2NQX A;  5FDQ A;  3RKE A;  4HHS A;  3FAQ A;  1DDX A;  4MSF A;  4RRW A;  2IKC A;  4N7A A;  3LN1 A;  5B72 A;  3MQE A;  3QL6 A;  3NIU A;  3I6N A;  2OYE P;  3S4F A;  4DL1 C;  1PRH A;  5FIW C;  1CXP C;  4QYQ A;  5JVY A;  3MDL A;  2R5L A;  1PXX A;  1EQG A;  3HS5 A;  3F9P C;  5JW1 A;  4RRX A;  3N8F A;  3OLT A;  4PH9 A;  4COX A;  5IKV A;  4O1Z A;  4KSZ A;  5JVZ A;  4NT3 A;  4OTY A;  4OEK A;  4Z0L A;  4FM5 A;  1D7W C;  1CQE A;  4RRY A;  3GC1 A;  1MYP C;  1IGX A;  3Q9K A;  3HS7 A;  3KRQ A;  2O86 A;  5GLS A;  5F19 A; 
#chains in the Genus database with same CATH topology
 3N8X A;  5IKR A;  1CVU A;  2GJM A;  1HT5 A;  2E9E A;  3GCJ A;  1U67 A;  4QJQ A;  2OYU P;  3V6Q A;  3OGW A;  1MHL C;  4LJJ A;  3N8W A;  4GM7 A;  5GH0 A;  1DNW C;  1PGE A;  5KIR A;  4KVJ A;  3QMO A;  3NTB A;  1EBV A;  3N8Z A;  3ZS0 C;  2Z5Z A;  3ERI A;  3QH0 A;  3NAK A;  5IKT A;  4M10 A;  3RR3 A;  4C1M C;  1D5L C;  4E1G A;  3GCK A;  3N8V A;  4RUT A;  3TGY A;  1EQH A;  3GCL A;  4GN6 A;  4HHR A;  3NT1 A;  2QQT A;  3R5O A;  3R5Q A;  2OJV A;  1IGZ A;  4NJB A;  4RRZ A;  5IKQ A;  2IPS A;  3N8W B;  3TZI A;  4Y55 A;  3LN0 A;  6COX A;  5FF1 A;  2PUM A;  5F1A A;  3PY4 A;  3OLU A;  3N8Y B;  3ZS1 C;  3KK6 A;  5COX A;  4RS0 A;  3N8Y A;  5HPW A;  1PTH A;  4OTJ A;  2QPK A;  1DNU C;  2QRB A;  2EFB A;  3R55 A;  1D2V C;  3Q7D A;  1FE2 A;  2PT3 A;  3QF1 A;  3NTG A;  4M11 A;  4PNX A;  3ERH A;  2EHA A;  3PGH A;  4KVK A;  1CX2 A;  3KRK A;  3UBA A;  3R4X A;  3FNL A;  3BXI A;  3SXV A;  3HS6 A;  1HT8 A;  3NYH A;  1Q4G A;  1DIY A;  2AYL A;  4IG5 A;  4KVL A;  2NQX A;  5FDQ A;  3RKE A;  4HHS A;  3FAQ A;  1DDX A;  4MSF A;  4RRW A;  2IKC A;  4N7A A;  3LN1 A;  5B72 A;  3MQE A;  3QL6 A;  3NIU A;  3I6N A;  2OYE P;  3S4F A;  4DL1 C;  1PRH A;  5FIW C;  1CXP C;  4QYQ A;  5JVY A;  3MDL A;  2R5L A;  1PXX A;  1EQG A;  3HS5 A;  3F9P C;  5JW1 A;  4RRX A;  3N8F A;  3OLT A;  4PH9 A;  4COX A;  5IKV A;  4O1Z A;  4KSZ A;  5JVZ A;  4NT3 A;  4OTY A;  4OEK A;  4Z0L A;  4FM5 A;  1D7W C;  1CQE A;  4RRY A;  3GC1 A;  1MYP C;  1IGX A;  3Q9K A;  3HS7 A;  3KRQ A;  2O86 A;  5GLS A;  5F19 A; 
#chains in the Genus database with same CATH homology
 3N8X A;  5IKR A;  1CVU A;  2GJM A;  1HT5 A;  2E9E A;  3GCJ A;  1U67 A;  4QJQ A;  2OYU P;  3V6Q A;  3OGW A;  1MHL C;  4LJJ A;  3N8W A;  4GM7 A;  5GH0 A;  1DNW C;  1PGE A;  5KIR A;  4KVJ A;  3QMO A;  3NTB A;  1EBV A;  3N8Z A;  3ZS0 C;  2Z5Z A;  3ERI A;  3QH0 A;  3NAK A;  5IKT A;  4M10 A;  3RR3 A;  4C1M C;  1D5L C;  4E1G A;  3GCK A;  3N8V A;  4RUT A;  3TGY A;  1EQH A;  3GCL A;  4GN6 A;  4HHR A;  3NT1 A;  2QQT A;  3R5O A;  3R5Q A;  2OJV A;  1IGZ A;  4NJB A;  4RRZ A;  5IKQ A;  2IPS A;  3N8W B;  3TZI A;  4Y55 A;  3LN0 A;  6COX A;  5FF1 A;  2PUM A;  5F1A A;  3PY4 A;  3OLU A;  3N8Y B;  3ZS1 C;  3KK6 A;  5COX A;  4RS0 A;  3N8Y A;  5HPW A;  1PTH A;  4OTJ A;  2QPK A;  1DNU C;  2QRB A;  2EFB A;  3R55 A;  1D2V C;  3Q7D A;  1FE2 A;  2PT3 A;  3QF1 A;  3NTG A;  4M11 A;  4PNX A;  3ERH A;  2EHA A;  3PGH A;  4KVK A;  1CX2 A;  3KRK A;  3UBA A;  3R4X A;  3FNL A;  3BXI A;  3SXV A;  3HS6 A;  1HT8 A;  3NYH A;  1Q4G A;  1DIY A;  2AYL A;  4IG5 A;  4KVL A;  2NQX A;  5FDQ A;  3RKE A;  4HHS A;  3FAQ A;  1DDX A;  4MSF A;  4RRW A;  2IKC A;  4N7A A;  3LN1 A;  5B72 A;  3MQE A;  3QL6 A;  3NIU A;  3I6N A;  2OYE P;  3S4F A;  4DL1 C;  1PRH A;  5FIW C;  1CXP C;  4QYQ A;  5JVY A;  3MDL A;  2R5L A;  1PXX A;  1EQG A;  3HS5 A;  3F9P C;  5JW1 A;  4RRX A;  3N8F A;  3OLT A;  4PH9 A;  4COX A;  5IKV A;  4O1Z A;  4KSZ A;  5JVZ A;  4NT3 A;  4OTY A;  4OEK A;  4Z0L A;  4FM5 A;  1D7W C;  1CQE A;  4RRY A;  3GC1 A;  1MYP C;  1IGX A;  3Q9K A;  3HS7 A;  3KRQ A;  2O86 A;  5GLS A;  5F19 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...