5GLFA

Structural insights into the interaction of p97 n-terminal domain and shp motif in derlin-1 rhomboid pseudoprotease
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
170
structure length
170
Chain Sequence
PNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLKGKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPIDDTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKRE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease.
pubmed doi rcsb
molecule tags Hydrolase/transport protein
source organism Homo sapiens
molecule keywords Transitional endoplasmic reticulum ATPase
total genus 48
structure length 170
sequence length 170
chains with identical sequence C, E, G
ec nomenclature ec 3.6.4.6: Vesicle-fusing ATPase.
pdb deposition date 2016-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02359 CDC48_N Cell division protein 48 (CDC48), N-terminal domain
A PF02933 CDC48_2 Cell division protein 48 (CDC48), domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.20 Mainly Beta Beta Barrel Barwin-like endoglucanases Barwin-like endoglucanases 5glfA01
3.10.330.10 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 5glfA02
5DYIA 1DMRA 5GLFA 1QDNA 2VPZA 5T5MD 1VC3B 1TWFA 1IW7D 1SIWA 2NAPA 3GTPA 5B6CA 1H5NA 2DMRA 4C2MA 1EU1A 5FTNA 4CRYG 2R92A 1H0HA 1AW8B 5C18A 3CQZA 4AZDA 3HKZA 3QC8A 3OUGA 2EEOB 2NVYA 5T5ID 1PT0A 1Y5IA 2Y0SA 3TIWA 1PQFA 3HU2A 2E2HA 1CZ5A 1E5VA 1TWAA 3IR5A 4QIWA 5FTMA 2VPXA 4D7ZB 3GTOA 3GTLA 4CRZA 5C1BA 3HU3A 4KDIA 2NYAA 2V3VA 3IR7A 4KO8A 4AAYA 1R7RA 1Y4ZA 5EPPA 5FTLA 2PJHB 2R7ZA 2YUJA 1R9TA 1E18A 2PMZA 2V45A 1Y1WA 4GA6A 4AONB 3O5AA 3DMRA 2NVXA 1Y1VA 3ML1A 1G8KA 2VUMA 3IR6A 1ZC1A 1QCSA 1S3SA 4RV0A 2IV2X 1KQGA 1WCMA 1TWGA 3FKIA 1I3QA 1TWCA 1PPYA 3PLXB 1CZ4A 2B63A 3QQ7A 1FDOA 1PT1A 1KQFA 1SFOA 5DYGA 2JIOA 2WAQA 4GA5A 3QQ8A 3GTJA 1R27A 2JA5A 3CF2A 4AOKB 1CR5A 4KODA 3HU1A 1I50A 3GTMA 4DMRA 1WLFA 1G8JA 4AYBA 2WB1A 1PQEA 1FDIA 1PYQA 2E2IA 1Q16A 1UHEA 4KLNA 5FTKA 2KI8A 2C45A 1AA6A 2YU9A 2JA7A 1K83A 1YLEA 1E61A 1TMOA 1PQHA 1PYUB 3GTQA 1DMSA 4CS0A 3GTGA 2JV2A 3TM7B 1TWHA 1OGYA 4KDLA 2JA6A 2R93A 2JIMA 2JIPA 2E7ZA 2JIQA 1E60A 2VPYA 5FTJA 3GTKA 2JIRA 1E32A 2VPWA 3QWZA 1UHDA 3H0GA
chains in the Genus database with same CATH superfamily
1N10A 5DYIA 1DMRA 3FPUA 2GFAA 1WC2A 5GLFA 1QDNA 3D30A 1BW4A 2VPZA 5T5MD 4ARIA 1VC3B 1TWFA 4JP7A 3SUKA 1IW7D 2Q1CX 1SIWA 1OA7A 2NAPA 2Q1DX 3GTPA 5B6CA 1H5NA 2DMRA 3SUMA 4C2MA 1EU1A 1YNJD 5FTNA 4FERA 3X2KA 4CRYG 2R92A 1H0HA 1AW8B 5C18A 5GLYA 3FPRA 3CQZA 1ZYRD 4AZDA 5D6XA 3HKZA 3QC8A 3OUGA 4FG4A 2EEOB 2NVYA 5T5ID 5D6YA 1PT0A 1Y5IA 5EQJB 2Y0SA 3TIWA 1PQFA 3HU2A 2E2HA 4JS7A 1CZ5A 1E5VA 1TWAA 1SMYD 3IR5A 4QIWA 2VPXA 5FTMA 4D7ZB 2A6HD 3GTOA 3GTLA 4CRZA 4FG2A 5C1BA 2Q1AX 3HU3A 2KY9A 1OA9A 2CW0D 2B25A 5GLXA 4KDIA 2NYAA 2V3VA 3IR7A 4JJOA 4KO8A 1R7RA 1Y4ZA 5EPPA 4AAYA 5FTLA 3FPTA 2PJHB 2R7ZA 2YUJA 1R9TA 2PWYA 1E18A 2PMZA 2V45A 1L8FA 4NOHA 5CCXA 2G6GA 4GA6A 3SULA 4AONB 1Y1WA 2AE0X 3O5AA 2PI8A 2ENGA 3DMRA 1Y1VA 2NVXA 3ML1A 1G8KA 2VUMA 2A6ED 3X2MA 4ZM7A 3IR6A 3LHDA 4AQ7A 4CQNA 1ZC1A 1QCSA 2PNWA 3X2GA 2BE5D 2O5JD 2GF7A 1S3SA 4RV0A 2IV2X 1KQGA 2A68D 1WCMA 2PJJA 1TWGA 2GAEA 3FKIA 2PICA 3ZJVA 4AS1A 1I3QA 3X2JA 1TWCA 1PPYA 2BH0A 1CZ4A 2HCZX 3PLXB 3ZJTA 2B63A 3QQ7A 1FDOA 1PT1A 1KQFA 1SFOA 3ENGA 4ENGA 5D6WA 5DYGA 2JIOA 2WAQA 4GA5A 3SUJA 2LW6A 3QQ8A 3X2IA 3GTJA 3MB5A 1R27A 3X2HA 3CF2A 2JA5A 3X2OA 3ZJUA 4AOKB 4UC4A 1CR5A 5CD1A 2XDPA 4KODA 2QQSA 4FIBA 3HU1A 5H4UA 1HD5A 2G5DA 2A69D 1I50A 3GTMA 4DMRA 1WLFA 2KQAA 4AVRA 1G8JA 4AYBA 1YNND 2WB1A 5GM9A 1PQEA 1FDIA 1PYQA 2E2IA 1Q16A 2MM2A 1UHEA 4KLNA 5FTKA 2KI8A 2C45A 1AA6A 2YU9A 1I9GA 2JA7A 3M3GA 4JCWA 4JP6A 1K83A 1YLEA 1E61A 1TMOA 1PQHA 1PYUB 2Q19X 3GTQA 1DMSA 2MM0A 4CS0A 3GTGA 3BQBA 5ERGB 3LGAA 2JV2A 4ARCA 5CCBA 4L48A 3ZGZA 3TM7B 3CZBA 1TWHA 1OGYA 4KDLA 1O54A 2JA6A 2R93A 2JIMA 3X2LA 2JIPA 2YVLA 2E7ZA 2JIQA 1E60A 2VPYA 5FTJA 3GTKA 2JIRA 1E32A 2VPWA 3QWZA 4FFTA 1UHDA 3X2NA 3X2PA 1BW3A 2Q18X 3H0GA 2QQRA
chains in the Genus database with same CATH topology
5DYIA 1DMRA 3FPUA 2GFAA 5GLFA 1QDNA 4ARIA 2VPZA 5T5MD 1VC3B 1TWFA 1IW7D 2Q1CX 1SIWA 2NAPA 2Q1DX 3GTPA 5B6CA 1H5NA 2DMRA 4C2MA 1EU1A 1YNJD 5FTNA 4CRYG 2R92A 1H0HA 1AW8B 5C18A 3FPRA 3CQZA 1ZYRD 4AZDA 5D6XA 3HKZA 3QC8A 3OUGA 2EEOB 2NVYA 5T5ID 5D6YA 1PT0A 1Y5IA 5EQJB 2Y0SA 3TIWA 1PQFA 3HU2A 2E2HA 1CZ5A 1E5VA 1TWAA 1SMYD 3IR5A 4QIWA 2VPXA 5FTMA 4D7ZB 2A6HD 3GTOA 3GTLA 4CRZA 5C1BA 2Q1AX 3HU3A 2KY9A 2CW0D 2B25A 4KDIA 2NYAA 2V3VA 3IR7A 4KO8A 4AAYA 1R7RA 1Y4ZA 5EPPA 3FPTA 5FTLA 2PJHB 2R7ZA 2YUJA 1R9TA 2PWYA 1E18A 2PMZA 2V45A 4NOHA 5CCXA 2G6GA 4GA6A 4AONB 1Y1WA 2AE0X 3O5AA 2PI8A 3DMRA 2NVXA 1Y1VA 3ML1A 1G8KA 2VUMA 2A6ED 3LHDA 4AQ7A 3IR6A 4CQNA 1ZC1A 1QCSA 2PNWA 2BE5D 2O5JD 2GF7A 1S3SA 4RV0A 2IV2X 1KQGA 2A68D 1WCMA 2PJJA 1TWGA 2GAEA 3FKIA 2PICA 3ZJVA 4AS1A 1I3QA 1TWCA 1PPYA 3PLXB 1CZ4A 3ZJTA 2B63A 3QQ7A 1FDOA 1PT1A 1KQFA 1SFOA 5D6WA 5DYGA 2JIOA 2WAQA 4GA5A 2LW6A 3QQ8A 3MB5A 3GTJA 1R27A 2JA5A 3CF2A 3ZJUA 4AOKB 4UC4A 1CR5A 5CD1A 2XDPA 4KODA 2QQSA 4FIBA 3HU1A 2G5DA 2A69D 1I50A 3GTMA 4DMRA 1WLFA 1G8JA 4AYBA 1YNND 2WB1A 1PQEA 1FDIA 1PYQA 2E2IA 1Q16A 2MM2A 1UHEA 4KLNA 5FTKA 2KI8A 2C45A 1AA6A 2YU9A 1I9GA 2JA7A 1K83A 1YLEA 1E61A 1TMOA 1PQHA 1PYUB 2Q19X 3GTQA 1DMSA 2MM0A 4CS0A 3GTGA 3BQBA 5ERGB 3LGAA 2JV2A 4ARCA 5CCBA 3ZGZA 3TM7B 3CZBA 1TWHA 1OGYA 4KDLA 1O54A 2JA6A 2R93A 2JIMA 2JIPA 2YVLA 2E7ZA 2JIQA 1E60A 2VPYA 5FTJA 3GTKA 2JIRA 1E32A 2VPWA 3QWZA 1UHDA 2Q18X 3H0GA 2QQRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DYI A;  1DMR A;  5GLF A;  1QDN A;  2VPZ A;  5T5M D;  1VC3 B;  1TWF A;  1IW7 D;  1SIW A;  2NAP A;  3GTP A;  5B6C A;  1H5N A;  2DMR A;  4C2M A;  1EU1 A;  5FTN A;  4CRY G;  2R92 A;  1H0H A;  1AW8 B;  5C18 A;  3CQZ A;  4AZD A;  3HKZ A;  3QC8 A;  3OUG A;  2EEO B;  2NVY A;  5T5I D;  1PT0 A;  1Y5I A;  2Y0S A;  3TIW A;  1PQF A;  3HU2 A;  2E2H A;  1CZ5 A;  1E5V A;  1TWA A;  3IR5 A;  4QIW A;  5FTM A;  2VPX A;  4D7Z B;  3GTO A;  3GTL A;  4CRZ A;  5C1B A;  3HU3 A;  4KDI A;  2NYA A;  2V3V A;  3IR7 A;  4KO8 A;  4AAY A;  1R7R A;  1Y4Z A;  5EPP A;  5FTL A;  2PJH B;  2R7Z A;  2YUJ A;  1R9T A;  1E18 A;  2PMZ A;  2V45 A;  1Y1W A;  4GA6 A;  4AON B;  3O5A A;  3DMR A;  2NVX A;  1Y1V A;  3ML1 A;  1G8K A;  2VUM A;  3IR6 A;  1ZC1 A;  1QCS A;  1S3S A;  4RV0 A;  2IV2 X;  1KQG A;  1WCM A;  1TWG A;  3FKI A;  1I3Q A;  1TWC A;  1PPY A;  3PLX B;  1CZ4 A;  2B63 A;  3QQ7 A;  1FDO A;  1PT1 A;  1KQF A;  1SFO A;  5DYG A;  2JIO A;  2WAQ A;  4GA5 A;  3QQ8 A;  3GTJ A;  1R27 A;  2JA5 A;  3CF2 A;  4AOK B;  1CR5 A;  4KOD A;  3HU1 A;  1I50 A;  3GTM A;  4DMR A;  1WLF A;  1G8J A;  4AYB A;  2WB1 A;  1PQE A;  1FDI A;  1PYQ A;  2E2I A;  1Q16 A;  1UHE A;  4KLN A;  5FTK A;  2KI8 A;  2C45 A;  1AA6 A;  2YU9 A;  2JA7 A;  1K83 A;  1YLE A;  1E61 A;  1TMO A;  1PQH A;  1PYU B;  3GTQ A;  1DMS A;  4CS0 A;  3GTG A;  2JV2 A;  3TM7 B;  1TWH A;  1OGY A;  4KDL A;  2JA6 A;  2R93 A;  2JIM A;  2JIP A;  2E7Z A;  2JIQ A;  1E60 A;  2VPY A;  5FTJ A;  3GTK A;  2JIR A;  1E32 A;  2VPW A;  3QWZ A;  1UHD A;  3H0G A; 
#chains in the Genus database with same CATH topology
 1N10 A;  5DYI A;  1DMR A;  3FPU A;  2GFA A;  1WC2 A;  5GLF A;  1QDN A;  3D30 A;  1BW4 A;  2VPZ A;  5T5M D;  4ARI A;  1VC3 B;  1TWF A;  4JP7 A;  3SUK A;  1IW7 D;  2Q1C X;  1SIW A;  1OA7 A;  2NAP A;  2Q1D X;  3GTP A;  5B6C A;  1H5N A;  2DMR A;  3SUM A;  4C2M A;  1EU1 A;  1YNJ D;  5FTN A;  4FER A;  3X2K A;  4CRY G;  2R92 A;  1H0H A;  1AW8 B;  5C18 A;  5GLY A;  3FPR A;  3CQZ A;  1ZYR D;  4AZD A;  5D6X A;  3HKZ A;  3QC8 A;  3OUG A;  4FG4 A;  2EEO B;  2NVY A;  5T5I D;  5D6Y A;  1PT0 A;  1Y5I A;  5EQJ B;  2Y0S A;  3TIW A;  1PQF A;  3HU2 A;  2E2H A;  4JS7 A;  1CZ5 A;  1E5V A;  1TWA A;  1SMY D;  3IR5 A;  4QIW A;  2VPX A;  5FTM A;  4D7Z B;  2A6H D;  3GTO A;  3GTL A;  4CRZ A;  4FG2 A;  5C1B A;  2Q1A X;  3HU3 A;  2KY9 A;  1OA9 A;  2CW0 D;  2B25 A;  5GLX A;  4KDI A;  2NYA A;  2V3V A;  3IR7 A;  4JJO A;  4KO8 A;  1R7R A;  1Y4Z A;  5EPP A;  4AAY A;  5FTL A;  3FPT A;  2PJH B;  2R7Z A;  2YUJ A;  1R9T A;  2PWY A;  1E18 A;  2PMZ A;  2V45 A;  1L8F A;  4NOH A;  5CCX A;  2G6G A;  4GA6 A;  3SUL A;  4AON B;  1Y1W A;  2AE0 X;  3O5A A;  2PI8 A;  2ENG A;  3DMR A;  1Y1V A;  2NVX A;  3ML1 A;  1G8K A;  2VUM A;  2A6E D;  3X2M A;  4ZM7 A;  3IR6 A;  3LHD A;  4AQ7 A;  4CQN A;  1ZC1 A;  1QCS A;  2PNW A;  3X2G A;  2BE5 D;  2O5J D;  2GF7 A;  1S3S A;  4RV0 A;  2IV2 X;  1KQG A;  2A68 D;  1WCM A;  2PJJ A;  1TWG A;  2GAE A;  3FKI A;  2PIC A;  3ZJV A;  4AS1 A;  1I3Q A;  3X2J A;  1TWC A;  1PPY A;  2BH0 A;  1CZ4 A;  2HCZ X;  3PLX B;  3ZJT A;  2B63 A;  3QQ7 A;  1FDO A;  1PT1 A;  1KQF A;  1SFO A;  3ENG A;  4ENG A;  5D6W A;  5DYG A;  2JIO A;  2WAQ A;  4GA5 A;  3SUJ A;  2LW6 A;  3QQ8 A;  3X2I A;  3GTJ A;  3MB5 A;  1R27 A;  3X2H A;  3CF2 A;  2JA5 A;  3X2O A;  3ZJU A;  4AOK B;  4UC4 A;  1CR5 A;  5CD1 A;  2XDP A;  4KOD A;  2QQS A;  4FIB A;  3HU1 A;  5H4U A;  1HD5 A;  2G5D A;  2A69 D;  1I50 A;  3GTM A;  4DMR A;  1WLF A;  2KQA A;  4AVR A;  1G8J A;  4AYB A;  1YNN D;  2WB1 A;  5GM9 A;  1PQE A;  1FDI A;  1PYQ A;  2E2I A;  1Q16 A;  2MM2 A;  1UHE A;  4KLN A;  5FTK A;  2KI8 A;  2C45 A;  1AA6 A;  2YU9 A;  1I9G A;  2JA7 A;  3M3G A;  4JCW A;  4JP6 A;  1K83 A;  1YLE A;  1E61 A;  1TMO A;  1PQH A;  1PYU B;  2Q19 X;  3GTQ A;  1DMS A;  2MM0 A;  4CS0 A;  3GTG A;  3BQB A;  5ERG B;  3LGA A;  2JV2 A;  4ARC A;  5CCB A;  4L48 A;  3ZGZ A;  3TM7 B;  3CZB A;  1TWH A;  1OGY A;  4KDL A;  1O54 A;  2JA6 A;  2R93 A;  2JIM A;  3X2L A;  2JIP A;  2YVL A;  2E7Z A;  2JIQ A;  1E60 A;  2VPY A;  5FTJ A;  3GTK A;  2JIR A;  1E32 A;  2VPW A;  3QWZ A;  4FFT A;  1UHD A;  3X2N A;  3X2P A;  1BW3 A;  2Q18 X;  3H0G A;  2QQR A; 
#chains in the Genus database with same CATH homology
 5DYI A;  1DMR A;  3FPU A;  2GFA A;  5GLF A;  1QDN A;  4ARI A;  2VPZ A;  5T5M D;  1VC3 B;  1TWF A;  1IW7 D;  2Q1C X;  1SIW A;  2NAP A;  2Q1D X;  3GTP A;  5B6C A;  1H5N A;  2DMR A;  4C2M A;  1EU1 A;  1YNJ D;  5FTN A;  4CRY G;  2R92 A;  1H0H A;  1AW8 B;  5C18 A;  3FPR A;  3CQZ A;  1ZYR D;  4AZD A;  5D6X A;  3HKZ A;  3QC8 A;  3OUG A;  2EEO B;  2NVY A;  5T5I D;  5D6Y A;  1PT0 A;  1Y5I A;  5EQJ B;  2Y0S A;  3TIW A;  1PQF A;  3HU2 A;  2E2H A;  1CZ5 A;  1E5V A;  1TWA A;  1SMY D;  3IR5 A;  4QIW A;  2VPX A;  5FTM A;  4D7Z B;  2A6H D;  3GTO A;  3GTL A;  4CRZ A;  5C1B A;  2Q1A X;  3HU3 A;  2KY9 A;  2CW0 D;  2B25 A;  4KDI A;  2NYA A;  2V3V A;  3IR7 A;  4KO8 A;  4AAY A;  1R7R A;  1Y4Z A;  5EPP A;  3FPT A;  5FTL A;  2PJH B;  2R7Z A;  2YUJ A;  1R9T A;  2PWY A;  1E18 A;  2PMZ A;  2V45 A;  4NOH A;  5CCX A;  2G6G A;  4GA6 A;  4AON B;  1Y1W A;  2AE0 X;  3O5A A;  2PI8 A;  3DMR A;  2NVX A;  1Y1V A;  3ML1 A;  1G8K A;  2VUM A;  2A6E D;  3LHD A;  4AQ7 A;  3IR6 A;  4CQN A;  1ZC1 A;  1QCS A;  2PNW A;  2BE5 D;  2O5J D;  2GF7 A;  1S3S A;  4RV0 A;  2IV2 X;  1KQG A;  2A68 D;  1WCM A;  2PJJ A;  1TWG A;  2GAE A;  3FKI A;  2PIC A;  3ZJV A;  4AS1 A;  1I3Q A;  1TWC A;  1PPY A;  3PLX B;  1CZ4 A;  3ZJT A;  2B63 A;  3QQ7 A;  1FDO A;  1PT1 A;  1KQF A;  1SFO A;  5D6W A;  5DYG A;  2JIO A;  2WAQ A;  4GA5 A;  2LW6 A;  3QQ8 A;  3MB5 A;  3GTJ A;  1R27 A;  2JA5 A;  3CF2 A;  3ZJU A;  4AOK B;  4UC4 A;  1CR5 A;  5CD1 A;  2XDP A;  4KOD A;  2QQS A;  4FIB A;  3HU1 A;  2G5D A;  2A69 D;  1I50 A;  3GTM A;  4DMR A;  1WLF A;  1G8J A;  4AYB A;  1YNN D;  2WB1 A;  1PQE A;  1FDI A;  1PYQ A;  2E2I A;  1Q16 A;  2MM2 A;  1UHE A;  4KLN A;  5FTK A;  2KI8 A;  2C45 A;  1AA6 A;  2YU9 A;  1I9G A;  2JA7 A;  1K83 A;  1YLE A;  1E61 A;  1TMO A;  1PQH A;  1PYU B;  2Q19 X;  3GTQ A;  1DMS A;  2MM0 A;  4CS0 A;  3GTG A;  3BQB A;  5ERG B;  3LGA A;  2JV2 A;  4ARC A;  5CCB A;  3ZGZ A;  3TM7 B;  3CZB A;  1TWH A;  1OGY A;  4KDL A;  1O54 A;  2JA6 A;  2R93 A;  2JIM A;  2JIP A;  2YVL A;  2E7Z A;  2JIQ A;  1E60 A;  2VPY A;  5FTJ A;  3GTK A;  2JIR A;  1E32 A;  2VPW A;  3QWZ A;  1UHD A;  2Q18 X;  3H0G A;  2QQR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...