5GRRA

Crystal structure of mcr-1
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
323
structure length
323
Chain Sequence
TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title High resolution crystal structure of the catalytic domain of MCR-1
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords Probable phosphatidylethanolamine transferase Mcr-1
total genus 128
structure length 323
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5grrA00
2IUCA 5DLWA 3NKPA 4YR1A 1ALHA 1KHLA 1Y6VA 3DYCA 2QZUA 3OT9A 5L0EA 2XRGA 4KM4A 2VQRA 4KAYA 2XR9A 1ALKA 4UOPA 3IDDA 3LXQA 4GTZA 4ZG9A 4MIVA 2W5SA 1KHNA 1N2KA 1N2LA 4NWXA 1ELZA 3IGZB 5EGHA 4LR8A 1E3CP 5C66A 1SHNA 5IJSA 3BDGB 3NKRA 3NKQA 3NKNA 4UPIA 3UO0A 4LRDA 2G9YA 3B5QA 2IFYA 1EQJA 1E2SP 4CYSA 3UN2A 3T00A 4LR9A 5INHA 4UPHA 1HDHA 3WAXA 1ZEBA 1URBA 3IGYB 3BDGA 3WAYA 2GSUA 5DLVA 1SHQA 4FDJA 5HRTA 5LIAA 3A52A 3DPCA 1ALJA 5GOVA 1EW2A 1KHJA 3SZZA 3MK1A 4QAXA 2ANHA 1EW9A 3SZYA 3NKMA 1HQAA 2GLQA 2RH6A 5LRNA 4GTYA 1E1ZP 3NKOA 3UN3A 3MK0A 1KHKA 1ELYA 3NVLA 1O98A 1ZEFA 3TWZA 1ED8A 4KJDA 1EW8A 2ZKTA 1KH4A 2GA3A 3M8WA 1E33P 4UOOA 2W5WA 1ELXA 5EGEA 3M7VA 1ZEDA 3TG0A 4LRCA 5DLTA 5IJQA 1KH7A 4MY4A 2W8SA 4CXUA 4CXSA 4LRFA 1P49A 3M8ZA 3BDFA 1AJDA 3WAVA 4LRAA 1AJCA 3UNYA 4UPLA 1FSUA 4KJGA 5LQQA 1EI6A 2W5QA 2W5VA 4KAVA 2D1GA 5AJ9A 1KH9A 2W5RA 3WBHA 3MK2A 5L0KA 2X98A 4MHXA 4ZG7A 1ALIA 3T01A 3KD8A 2IUCB 4LRBA 4TN0A 4FDIA 3E2DA 5TJ3A 4CXKA 1B8JA 1KH5A 4GTWA 4NWJA 1AJBA 4UPKA 5K4PA 1URAA 3Q3QA 4LREA 4GTXA 3M8YA 4LR2A 3WAWA 1Y7AA 4ZG6A 3UN5A 1ED9A 1ANIA 3TX0A 3T02A 4B56A 1ANJA 4N7TA 4UORA 3ED4A 1AJAA 3BDHA 3CMRA 4LR7A 4LQYA 1K7HA 2W5XA 4ZGAA 5L0BA 5GRRA 5LRMA 2GSNA 2W5TA 1O99A 2W8DA 4CYRA 5KXAA 1EJJA 1AUKA 1HJKA 2GSOA
chains in the Genus database with same CATH superfamily
2IUCA 5DLWA 3NKPA 4YR1A 1ALHA 1KHLA 1Y6VA 3DYCA 2QZUA 3OT9A 5L0EA 2XRGA 4KM4A 2VQRA 4KAYA 2XR9A 1ALKA 4UOPA 3IDDA 3LXQA 4GTZA 4ZG9A 4MIVA 2W5SA 1KHNA 1N2KA 1N2LA 4NWXA 1ELZA 3IGZB 5EGHA 4LR8A 1E3CP 5C66A 1SHNA 5IJSA 3BDGB 3NKRA 3NKQA 3NKNA 4UPIA 3UO0A 4LRDA 2G9YA 3B5QA 2IFYA 1EQJA 1E2SP 4CYSA 3UN2A 3T00A 4LR9A 5INHA 4UPHA 1HDHA 3WAXA 1ZEBA 1URBA 3IGYB 3BDGA 3WAYA 2GSUA 5DLVA 1SHQA 4FDJA 5HRTA 5LIAA 3A52A 3DPCA 1ALJA 5GOVA 1EW2A 1KHJA 3SZZA 3MK1A 4QAXA 2ANHA 1EW9A 3SZYA 3NKMA 1HQAA 2GLQA 2RH6A 5LRNA 4GTYA 1E1ZP 3NKOA 3UN3A 3MK0A 1KHKA 1ELYA 3NVLA 1O98A 1ZEFA 3TWZA 1ED8A 4KJDA 1EW8A 2ZKTA 1KH4A 2GA3A 3M8WA 1E33P 4UOOA 2W5WA 1ELXA 5EGEA 3M7VA 1ZEDA 3TG0A 4LRCA 5DLTA 5IJQA 1KH7A 4MY4A 2W8SA 4CXUA 4CXSA 4LRFA 1P49A 3M8ZA 3BDFA 1AJDA 3WAVA 4LRAA 1AJCA 3UNYA 4UPLA 1FSUA 4KJGA 5LQQA 1EI6A 2W5QA 2W5VA 4KAVA 2D1GA 5AJ9A 1KH9A 2W5RA 3WBHA 3MK2A 5L0KA 2X98A 4MHXA 4ZG7A 1ALIA 3T01A 3KD8A 2IUCB 4LRBA 4TN0A 4FDIA 3E2DA 5TJ3A 4CXKA 1B8JA 1KH5A 4GTWA 4NWJA 1AJBA 4UPKA 5K4PA 1URAA 3Q3QA 4LREA 4GTXA 3M8YA 4LR2A 3WAWA 1Y7AA 4ZG6A 3UN5A 1ED9A 1ANIA 3TX0A 3T02A 4B56A 1ANJA 4N7TA 4UORA 3ED4A 1AJAA 3BDHA 3CMRA 4LR7A 4LQYA 1K7HA 2W5XA 4ZGAA 5L0BA 5GRRA 5LRMA 2GSNA 2W5TA 1O99A 2W8DA 4CYRA 5KXAA 1EJJA 1AUKA 1HJKA 2GSOA
chains in the Genus database with same CATH topology
2IUCA 5DLWA 3NKPA 4YR1A 1ALHA 1KHLA 1Y6VA 3DYCA 2QZUA 3OT9A 5L0EA 2XRGA 4KM4A 2VQRA 4KAYA 2XR9A 1ALKA 4UOPA 3IDDA 3LXQA 4GTZA 4ZG9A 4MIVA 2W5SA 1KHNA 1N2KA 1N2LA 4NWXA 1ELZA 3IGZB 5EGHA 4LR8A 1E3CP 5C66A 1SHNA 5IJSA 3BDGB 3NKRA 3NKQA 3NKNA 4UPIA 3UO0A 4LRDA 2G9YA 3B5QA 2IFYA 1EQJA 1E2SP 4CYSA 3UN2A 3T00A 4LR9A 5INHA 4UPHA 1HDHA 3WAXA 1ZEBA 1URBA 3IGYB 3BDGA 3WAYA 2GSUA 5DLVA 1SHQA 4FDJA 5HRTA 5LIAA 3A52A 3DPCA 1ALJA 5GOVA 1EW2A 1KHJA 3SZZA 3MK1A 4QAXA 2ANHA 1EW9A 3SZYA 3NKMA 1HQAA 2GLQA 2RH6A 5LRNA 4GTYA 1E1ZP 3NKOA 3UN3A 3MK0A 1KHKA 1ELYA 3NVLA 1O98A 1ZEFA 3TWZA 1ED8A 4KJDA 1EW8A 2ZKTA 1KH4A 2GA3A 3M8WA 1E33P 4UOOA 2W5WA 1ELXA 5EGEA 3M7VA 1ZEDA 3TG0A 4LRCA 5DLTA 5IJQA 1KH7A 4MY4A 2W8SA 4CXUA 4CXSA 4LRFA 1P49A 3M8ZA 3BDFA 1AJDA 3WAVA 4LRAA 1AJCA 3UNYA 4UPLA 1FSUA 4KJGA 5LQQA 1EI6A 2W5QA 2W5VA 4KAVA 2D1GA 5AJ9A 1KH9A 2W5RA 3WBHA 3MK2A 5L0KA 2X98A 4MHXA 4ZG7A 1ALIA 3T01A 3KD8A 2IUCB 4LRBA 4TN0A 4FDIA 3E2DA 5TJ3A 4CXKA 1B8JA 1KH5A 4GTWA 4NWJA 1AJBA 4UPKA 5K4PA 1URAA 3Q3QA 4LREA 4GTXA 3M8YA 4LR2A 3WAWA 1Y7AA 4ZG6A 3UN5A 1ED9A 1ANIA 3TX0A 3T02A 4B56A 1ANJA 4N7TA 4UORA 3ED4A 1AJAA 3BDHA 3CMRA 4LR7A 4LQYA 1K7HA 2W5XA 4ZGAA 5L0BA 5GRRA 5LRMA 2GSNA 2W5TA 1O99A 2W8DA 4CYRA 5KXAA 1EJJA 1AUKA 1HJKA 2GSOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IUC A;  5DLW A;  3NKP A;  4YR1 A;  1ALH A;  1KHL A;  1Y6V A;  3DYC A;  2QZU A;  3OT9 A;  5L0E A;  2XRG A;  4KM4 A;  2VQR A;  4KAY A;  2XR9 A;  1ALK A;  4UOP A;  3IDD A;  3LXQ A;  4GTZ A;  4ZG9 A;  4MIV A;  2W5S A;  1KHN A;  1N2K A;  1N2L A;  4NWX A;  1ELZ A;  3IGZ B;  5EGH A;  4LR8 A;  1E3C P;  5C66 A;  1SHN A;  5IJS A;  3BDG B;  3NKR A;  3NKQ A;  3NKN A;  4UPI A;  3UO0 A;  4LRD A;  2G9Y A;  3B5Q A;  2IFY A;  1EQJ A;  1E2S P;  4CYS A;  3UN2 A;  3T00 A;  4LR9 A;  5INH A;  4UPH A;  1HDH A;  3WAX A;  1ZEB A;  1URB A;  3IGY B;  3BDG A;  3WAY A;  2GSU A;  5DLV A;  1SHQ A;  4FDJ A;  5HRT A;  5LIA A;  3A52 A;  3DPC A;  1ALJ A;  5GOV A;  1EW2 A;  1KHJ A;  3SZZ A;  3MK1 A;  4QAX A;  2ANH A;  1EW9 A;  3SZY A;  3NKM A;  1HQA A;  2GLQ A;  2RH6 A;  5LRN A;  4GTY A;  1E1Z P;  3NKO A;  3UN3 A;  3MK0 A;  1KHK A;  1ELY A;  3NVL A;  1O98 A;  1ZEF A;  3TWZ A;  1ED8 A;  4KJD A;  1EW8 A;  2ZKT A;  1KH4 A;  2GA3 A;  3M8W A;  1E33 P;  4UOO A;  2W5W A;  1ELX A;  5EGE A;  3M7V A;  1ZED A;  3TG0 A;  4LRC A;  5DLT A;  5IJQ A;  1KH7 A;  4MY4 A;  2W8S A;  4CXU A;  4CXS A;  4LRF A;  1P49 A;  3M8Z A;  3BDF A;  1AJD A;  3WAV A;  4LRA A;  1AJC A;  3UNY A;  4UPL A;  1FSU A;  4KJG A;  5LQQ A;  1EI6 A;  2W5Q A;  2W5V A;  4KAV A;  2D1G A;  5AJ9 A;  1KH9 A;  2W5R A;  3WBH A;  3MK2 A;  5L0K A;  2X98 A;  4MHX A;  4ZG7 A;  1ALI A;  3T01 A;  3KD8 A;  2IUC B;  4LRB A;  4TN0 A;  4FDI A;  3E2D A;  5TJ3 A;  4CXK A;  1B8J A;  1KH5 A;  4GTW A;  4NWJ A;  1AJB A;  4UPK A;  5K4P A;  1URA A;  3Q3Q A;  4LRE A;  4GTX A;  3M8Y A;  4LR2 A;  3WAW A;  1Y7A A;  4ZG6 A;  3UN5 A;  1ED9 A;  1ANI A;  3TX0 A;  3T02 A;  4B56 A;  1ANJ A;  4N7T A;  4UOR A;  3ED4 A;  1AJA A;  3BDH A;  3CMR A;  4LR7 A;  4LQY A;  1K7H A;  2W5X A;  4ZGA A;  5L0B A;  5GRR A;  5LRM A;  2GSN A;  2W5T A;  1O99 A;  2W8D A;  4CYR A;  5KXA A;  1EJJ A;  1AUK A;  1HJK A;  2GSO A; 
#chains in the Genus database with same CATH topology
 2IUC A;  5DLW A;  3NKP A;  4YR1 A;  1ALH A;  1KHL A;  1Y6V A;  3DYC A;  2QZU A;  3OT9 A;  5L0E A;  2XRG A;  4KM4 A;  2VQR A;  4KAY A;  2XR9 A;  1ALK A;  4UOP A;  3IDD A;  3LXQ A;  4GTZ A;  4ZG9 A;  4MIV A;  2W5S A;  1KHN A;  1N2K A;  1N2L A;  4NWX A;  1ELZ A;  3IGZ B;  5EGH A;  4LR8 A;  1E3C P;  5C66 A;  1SHN A;  5IJS A;  3BDG B;  3NKR A;  3NKQ A;  3NKN A;  4UPI A;  3UO0 A;  4LRD A;  2G9Y A;  3B5Q A;  2IFY A;  1EQJ A;  1E2S P;  4CYS A;  3UN2 A;  3T00 A;  4LR9 A;  5INH A;  4UPH A;  1HDH A;  3WAX A;  1ZEB A;  1URB A;  3IGY B;  3BDG A;  3WAY A;  2GSU A;  5DLV A;  1SHQ A;  4FDJ A;  5HRT A;  5LIA A;  3A52 A;  3DPC A;  1ALJ A;  5GOV A;  1EW2 A;  1KHJ A;  3SZZ A;  3MK1 A;  4QAX A;  2ANH A;  1EW9 A;  3SZY A;  3NKM A;  1HQA A;  2GLQ A;  2RH6 A;  5LRN A;  4GTY A;  1E1Z P;  3NKO A;  3UN3 A;  3MK0 A;  1KHK A;  1ELY A;  3NVL A;  1O98 A;  1ZEF A;  3TWZ A;  1ED8 A;  4KJD A;  1EW8 A;  2ZKT A;  1KH4 A;  2GA3 A;  3M8W A;  1E33 P;  4UOO A;  2W5W A;  1ELX A;  5EGE A;  3M7V A;  1ZED A;  3TG0 A;  4LRC A;  5DLT A;  5IJQ A;  1KH7 A;  4MY4 A;  2W8S A;  4CXU A;  4CXS A;  4LRF A;  1P49 A;  3M8Z A;  3BDF A;  1AJD A;  3WAV A;  4LRA A;  1AJC A;  3UNY A;  4UPL A;  1FSU A;  4KJG A;  5LQQ A;  1EI6 A;  2W5Q A;  2W5V A;  4KAV A;  2D1G A;  5AJ9 A;  1KH9 A;  2W5R A;  3WBH A;  3MK2 A;  5L0K A;  2X98 A;  4MHX A;  4ZG7 A;  1ALI A;  3T01 A;  3KD8 A;  2IUC B;  4LRB A;  4TN0 A;  4FDI A;  3E2D A;  5TJ3 A;  4CXK A;  1B8J A;  1KH5 A;  4GTW A;  4NWJ A;  1AJB A;  4UPK A;  5K4P A;  1URA A;  3Q3Q A;  4LRE A;  4GTX A;  3M8Y A;  4LR2 A;  3WAW A;  1Y7A A;  4ZG6 A;  3UN5 A;  1ED9 A;  1ANI A;  3TX0 A;  3T02 A;  4B56 A;  1ANJ A;  4N7T A;  4UOR A;  3ED4 A;  1AJA A;  3BDH A;  3CMR A;  4LR7 A;  4LQY A;  1K7H A;  2W5X A;  4ZGA A;  5L0B A;  5GRR A;  5LRM A;  2GSN A;  2W5T A;  1O99 A;  2W8D A;  4CYR A;  5KXA A;  1EJJ A;  1AUK A;  1HJK A;  2GSO A; 
#chains in the Genus database with same CATH homology
 2IUC A;  5DLW A;  3NKP A;  4YR1 A;  1ALH A;  1KHL A;  1Y6V A;  3DYC A;  2QZU A;  3OT9 A;  5L0E A;  2XRG A;  4KM4 A;  2VQR A;  4KAY A;  2XR9 A;  1ALK A;  4UOP A;  3IDD A;  3LXQ A;  4GTZ A;  4ZG9 A;  4MIV A;  2W5S A;  1KHN A;  1N2K A;  1N2L A;  4NWX A;  1ELZ A;  3IGZ B;  5EGH A;  4LR8 A;  1E3C P;  5C66 A;  1SHN A;  5IJS A;  3BDG B;  3NKR A;  3NKQ A;  3NKN A;  4UPI A;  3UO0 A;  4LRD A;  2G9Y A;  3B5Q A;  2IFY A;  1EQJ A;  1E2S P;  4CYS A;  3UN2 A;  3T00 A;  4LR9 A;  5INH A;  4UPH A;  1HDH A;  3WAX A;  1ZEB A;  1URB A;  3IGY B;  3BDG A;  3WAY A;  2GSU A;  5DLV A;  1SHQ A;  4FDJ A;  5HRT A;  5LIA A;  3A52 A;  3DPC A;  1ALJ A;  5GOV A;  1EW2 A;  1KHJ A;  3SZZ A;  3MK1 A;  4QAX A;  2ANH A;  1EW9 A;  3SZY A;  3NKM A;  1HQA A;  2GLQ A;  2RH6 A;  5LRN A;  4GTY A;  1E1Z P;  3NKO A;  3UN3 A;  3MK0 A;  1KHK A;  1ELY A;  3NVL A;  1O98 A;  1ZEF A;  3TWZ A;  1ED8 A;  4KJD A;  1EW8 A;  2ZKT A;  1KH4 A;  2GA3 A;  3M8W A;  1E33 P;  4UOO A;  2W5W A;  1ELX A;  5EGE A;  3M7V A;  1ZED A;  3TG0 A;  4LRC A;  5DLT A;  5IJQ A;  1KH7 A;  4MY4 A;  2W8S A;  4CXU A;  4CXS A;  4LRF A;  1P49 A;  3M8Z A;  3BDF A;  1AJD A;  3WAV A;  4LRA A;  1AJC A;  3UNY A;  4UPL A;  1FSU A;  4KJG A;  5LQQ A;  1EI6 A;  2W5Q A;  2W5V A;  4KAV A;  2D1G A;  5AJ9 A;  1KH9 A;  2W5R A;  3WBH A;  3MK2 A;  5L0K A;  2X98 A;  4MHX A;  4ZG7 A;  1ALI A;  3T01 A;  3KD8 A;  2IUC B;  4LRB A;  4TN0 A;  4FDI A;  3E2D A;  5TJ3 A;  4CXK A;  1B8J A;  1KH5 A;  4GTW A;  4NWJ A;  1AJB A;  4UPK A;  5K4P A;  1URA A;  3Q3Q A;  4LRE A;  4GTX A;  3M8Y A;  4LR2 A;  3WAW A;  1Y7A A;  4ZG6 A;  3UN5 A;  1ED9 A;  1ANI A;  3TX0 A;  3T02 A;  4B56 A;  1ANJ A;  4N7T A;  4UOR A;  3ED4 A;  1AJA A;  3BDH A;  3CMR A;  4LR7 A;  4LQY A;  1K7H A;  2W5X A;  4ZGA A;  5L0B A;  5GRR A;  5LRM A;  2GSN A;  2W5T A;  1O99 A;  2W8D A;  4CYR A;  5KXA A;  1EJJ A;  1AUK A;  1HJK A;  2GSO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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