5GRRA

Crystal structure of mcr-1
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
Knots found
sequence length
323
structure length
323
Chain Sequence
b'TIYHAKDAVQATKPDMRKPRLVVFVVGETARADHVSFNGYERDTFPQLAKIDGVTNFSNVTSCGTSTAYSVPCMFSYLGADEYDVDTAKYQENVLDTLDRLGVSILWRDNNSDSKGVMDKLPKAQFADYKSATNNAICNTNPYNECRDVGMLVGLDDFVAANNGKDMLIMLHQMGNHGPAYFKRYDEKFAKFTPVCEGNELAKCEHQSLINAYDNALLATDDFIAQSIQWLQTHSNAYDVSMLYVSDHGESLGENGVYLHGMPNAFAPKEQRSVPAFFWTDKQTGITPMATDTVLTHDAITPTLLKLFDVTADKVKDRTAFIR'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title High resolution crystal structure of the catalytic domain of MCR-1
pubmed doi rcsb
molecule keywords Probable phosphatidylethanolamine transferase Mcr-1
source organism Escherichia coli
molecule tags Transferase
total genus 128
structure length 323
sequence length 323
other databases KnotProt 2.0: S +31
ec nomenclature ec 2.7.-.-:
pdb deposition date 2016-08-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00884 Sulfatase Sulfatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 5grrA00
4LRAA 3M7VA 3IDDA 5HRTA 1AUKA 1SHNA 1EW9A 3UN5A 4GTZA 4B56A 4FDIA 1KH7A 1ZEFA 2GSUA 3BDGB 4LREA 3Q3QA 5LIAA 1ELYA 4GTYA 4UPKA 1AJAA 1E2SP 3TX0A 5IJQA 4KJDA 1N2LA 4ZG9A 4UOOA 4CYSA 4MHXA 4NWXA 3A52A 2GSOA 3NKRA 3BDHA 3SZZA 5L0BA 2XRGA 2IUCA 3LXQA 1AJBA 2G9YA 4LRBA 1FSUA 2W5RA 1E3CP 3IGZB 1E1ZP 3SZYA 3UN2A 4CXKA 4NWJA 3IGYB 4LRCA 4CXSA 3MK1A 3CMRA 3UNYA 1E33P 3OT9A 3MK2A 3NKOA 1ZEBA 2GLQA 2IFYA 4UORA 5KXAA 1ALJA 3M8ZA 1EI6A 1EQJA 4KJGA 1KHKA 5L0KA 2W5XA 2D1GA 4UPHA 1ED8A 1KH9A 1Y6VA 3T00A 1O98A 3UN3A 3NKNA 3WAYA 3NKQA 5INHA 1HQAA 2ANHA 5L0EA 1AJCA 2W5VA 3DPCA 3ED4A 5GRRA 2GSNA 3NVLA 1ALIA 1HDHA 1URAA 1AJDA 2IUCB 4GTXA 4LR8A 5IJSA 1ED9A 1HJKA 2RH6A 2W5WA 3TG0A 2W5TA 4LR2A 3WAXA 1ELZA 4UOPA 4CYRA 5DLWA 2QZUA 1EW8A 2ZKTA 5K4PA 5DLVA 4FDJA 4CXUA 3M8WA 1ALKA 1O99A 1KH5A 2VQRA 5EGEA 5LQQA 3WAWA 1N2KA 2W8SA 5TJ3A 1KH4A 4KM4A 4LRDA 1KHLA 1K7HA 1ANJA 3UO0A 4GTWA 4LRFA 3MK0A 5C66A 2W5QA 3T02A 4LR7A 1EW2A 3B5QA 4ZG6A 3T01A 2W5SA 3BDFA 4MY4A 2GA3A 4TN0A 5LRNA 3KD8A 4QAXA 4N7TA 1KHJA 1ZEDA 1URBA 3E2DA 3M8YA 4LQYA 4MIVA 1ANIA 1B8JA 1P49A 1ELXA 3NKPA 4UPLA 2W8DA 3BDGA 3DYCA 1EJJA 4KAYA 3WBHA 1SHQA 1KHNA 1ALHA 4UPIA 5GOVA 3TWZA 4ZG7A 2X98A 4KAVA 5EGHA 3WAVA 5AJ9A 1Y7AA 2XR9A 3NKMA 5DLTA 4YR1A 4LR9A 4ZGAA 5LRMA
chains in the Genus database with same CATH superfamily
4LRAA 3M7VA 3IDDA 5HRTA 1AUKA 1SHNA 1EW9A 3UN5A 4GTZA 4B56A 4FDIA 1KH7A 1ZEFA 2GSUA 3BDGB 4LREA 3Q3QA 5LIAA 1ELYA 4GTYA 4UPKA 1AJAA 1E2SP 3TX0A 5IJQA 4KJDA 1N2LA 4ZG9A 4UOOA 4CYSA 4MHXA 4NWXA 3A52A 2GSOA 3NKRA 3BDHA 3SZZA 5L0BA 2XRGA 2IUCA 3LXQA 1AJBA 2G9YA 4LRBA 1FSUA 2W5RA 1E3CP 3IGZB 1E1ZP 3SZYA 3UN2A 4CXKA 4NWJA 3IGYB 4LRCA 4CXSA 3MK1A 3CMRA 3UNYA 1E33P 3OT9A 3MK2A 3NKOA 1ZEBA 2GLQA 2IFYA 4UORA 5KXAA 1ALJA 3M8ZA 1EI6A 1EQJA 4KJGA 1KHKA 5L0KA 2W5XA 2D1GA 4UPHA 1ED8A 1KH9A 1Y6VA 3T00A 1O98A 3UN3A 3NKNA 3WAYA 3NKQA 5INHA 1HQAA 2ANHA 5L0EA 1AJCA 2W5VA 3DPCA 3ED4A 5GRRA 2GSNA 3NVLA 1ALIA 1HDHA 1URAA 1AJDA 2IUCB 4GTXA 4LR8A 5IJSA 1ED9A 1HJKA 2RH6A 2W5WA 3TG0A 2W5TA 4LR2A 3WAXA 1ELZA 4UOPA 4CYRA 5DLWA 2QZUA 1EW8A 2ZKTA 5K4PA 5DLVA 4FDJA 4CXUA 3M8WA 1ALKA 1O99A 1KH5A 2VQRA 5EGEA 5LQQA 3WAWA 1N2KA 2W8SA 5TJ3A 1KH4A 4KM4A 4LRDA 1KHLA 1K7HA 1ANJA 3UO0A 4GTWA 4LRFA 3MK0A 5C66A 2W5QA 3T02A 4LR7A 1EW2A 3B5QA 4ZG6A 3T01A 2W5SA 3BDFA 4MY4A 2GA3A 4TN0A 5LRNA 3KD8A 4QAXA 4N7TA 1KHJA 1ZEDA 1URBA 3E2DA 3M8YA 4LQYA 4MIVA 1ANIA 1B8JA 1P49A 1ELXA 3NKPA 4UPLA 2W8DA 3BDGA 3DYCA 1EJJA 4KAYA 3WBHA 1SHQA 1KHNA 1ALHA 4UPIA 5GOVA 3TWZA 4ZG7A 2X98A 4KAVA 5EGHA 3WAVA 5AJ9A 1Y7AA 2XR9A 3NKMA 5DLTA 4YR1A 4LR9A 4ZGAA 5LRMA
chains in the Genus database with same CATH topology
4LRAA 3M7VA 3IDDA 5HRTA 1AUKA 1SHNA 1EW9A 3UN5A 4GTZA 4B56A 4FDIA 1KH7A 1ZEFA 2GSUA 3BDGB 4LREA 3Q3QA 5LIAA 1ELYA 4GTYA 4UPKA 1AJAA 1E2SP 3TX0A 5IJQA 4KJDA 1N2LA 4ZG9A 4UOOA 4CYSA 4MHXA 4NWXA 3A52A 2GSOA 3NKRA 3BDHA 3SZZA 5L0BA 2XRGA 2IUCA 3LXQA 1AJBA 2G9YA 4LRBA 1FSUA 2W5RA 1E3CP 3IGZB 1E1ZP 3SZYA 3UN2A 4CXKA 4NWJA 3IGYB 4LRCA 4CXSA 3MK1A 3CMRA 3UNYA 1E33P 3OT9A 3MK2A 3NKOA 1ZEBA 2GLQA 2IFYA 4UORA 5KXAA 1ALJA 3M8ZA 1EI6A 1EQJA 4KJGA 1KHKA 5L0KA 2W5XA 2D1GA 4UPHA 1ED8A 1KH9A 1Y6VA 3T00A 1O98A 3UN3A 3NKNA 3WAYA 3NKQA 5INHA 1HQAA 2ANHA 5L0EA 1AJCA 2W5VA 3DPCA 3ED4A 5GRRA 2GSNA 3NVLA 1ALIA 1HDHA 1URAA 1AJDA 2IUCB 4GTXA 4LR8A 5IJSA 1ED9A 1HJKA 2RH6A 2W5WA 3TG0A 2W5TA 4LR2A 3WAXA 1ELZA 4UOPA 4CYRA 5DLWA 2QZUA 1EW8A 2ZKTA 5K4PA 5DLVA 4FDJA 4CXUA 3M8WA 1ALKA 1O99A 1KH5A 2VQRA 5EGEA 5LQQA 3WAWA 1N2KA 2W8SA 5TJ3A 1KH4A 4KM4A 4LRDA 1KHLA 1K7HA 1ANJA 3UO0A 4GTWA 4LRFA 3MK0A 5C66A 2W5QA 3T02A 4LR7A 1EW2A 3B5QA 4ZG6A 3T01A 2W5SA 3BDFA 4MY4A 2GA3A 4TN0A 5LRNA 3KD8A 4QAXA 4N7TA 1KHJA 1ZEDA 1URBA 3E2DA 3M8YA 4LQYA 4MIVA 1ANIA 1B8JA 1P49A 1ELXA 3NKPA 4UPLA 2W8DA 3BDGA 3DYCA 1EJJA 4KAYA 3WBHA 1SHQA 1KHNA 1ALHA 4UPIA 5GOVA 3TWZA 4ZG7A 2X98A 4KAVA 5EGHA 3WAVA 5AJ9A 1Y7AA 2XR9A 3NKMA 5DLTA 4YR1A 4LR9A 4ZGAA 5LRMA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4LRA A;  3M7V A;  3IDD A;  5HRT A;  1AUK A;  1SHN A;  1EW9 A;  3UN5 A;  4GTZ A;  4B56 A;  4FDI A;  1KH7 A;  1ZEF A;  2GSU A;  3BDG B;  4LRE A;  3Q3Q A;  5LIA A;  1ELY A;  4GTY A;  4UPK A;  1AJA A;  1E2S P;  3TX0 A;  5IJQ A;  4KJD A;  1N2L A;  4ZG9 A;  4UOO A;  4CYS A;  4MHX A;  4NWX A;  3A52 A;  2GSO A;  3NKR A;  3BDH A;  3SZZ A;  5L0B A;  2XRG A;  2IUC A;  3LXQ A;  1AJB A;  2G9Y A;  4LRB A;  1FSU A;  2W5R A;  1E3C P;  3IGZ B;  1E1Z P;  3SZY A;  3UN2 A;  4CXK A;  4NWJ A;  3IGY B;  4LRC A;  4CXS A;  3MK1 A;  3CMR A;  3UNY A;  1E33 P;  3OT9 A;  3MK2 A;  3NKO A;  1ZEB A;  2GLQ A;  2IFY A;  4UOR A;  5KXA A;  1ALJ A;  3M8Z A;  1EI6 A;  1EQJ A;  4KJG A;  1KHK A;  5L0K A;  2W5X A;  2D1G A;  4UPH A;  1ED8 A;  1KH9 A;  1Y6V A;  3T00 A;  1O98 A;  3UN3 A;  3NKN A;  3WAY A;  3NKQ A;  5INH A;  1HQA A;  2ANH A;  5L0E A;  1AJC A;  2W5V A;  3DPC A;  3ED4 A;  5GRR A;  2GSN A;  3NVL A;  1ALI A;  1HDH A;  1URA A;  1AJD A;  2IUC B;  4GTX A;  4LR8 A;  5IJS A;  1ED9 A;  1HJK A;  2RH6 A;  2W5W A;  3TG0 A;  2W5T A;  4LR2 A;  3WAX A;  1ELZ A;  4UOP A;  4CYR A;  5DLW A;  2QZU A;  1EW8 A;  2ZKT A;  5K4P A;  5DLV A;  4FDJ A;  4CXU A;  3M8W A;  1ALK A;  1O99 A;  1KH5 A;  2VQR A;  5EGE A;  5LQQ A;  3WAW A;  1N2K A;  2W8S A;  5TJ3 A;  1KH4 A;  4KM4 A;  4LRD A;  1KHL A;  1K7H A;  1ANJ A;  3UO0 A;  4GTW A;  4LRF A;  3MK0 A;  5C66 A;  2W5Q A;  3T02 A;  4LR7 A;  1EW2 A;  3B5Q A;  4ZG6 A;  3T01 A;  2W5S A;  3BDF A;  4MY4 A;  2GA3 A;  4TN0 A;  5LRN A;  3KD8 A;  4QAX A;  4N7T A;  1KHJ A;  1ZED A;  1URB A;  3E2D A;  3M8Y A;  4LQY A;  4MIV A;  1ANI A;  1B8J A;  1P49 A;  1ELX A;  3NKP A;  4UPL A;  2W8D A;  3BDG A;  3DYC A;  1EJJ A;  4KAY A;  3WBH A;  1SHQ A;  1KHN A;  1ALH A;  4UPI A;  5GOV A;  3TWZ A;  4ZG7 A;  2X98 A;  4KAV A;  5EGH A;  3WAV A;  5AJ9 A;  1Y7A A;  2XR9 A;  3NKM A;  5DLT A;  4YR1 A;  4LR9 A;  4ZGA A;  5LRM A; 
#chains in the Genus database with same CATH topology
 4LRA A;  3M7V A;  3IDD A;  5HRT A;  1AUK A;  1SHN A;  1EW9 A;  3UN5 A;  4GTZ A;  4B56 A;  4FDI A;  1KH7 A;  1ZEF A;  2GSU A;  3BDG B;  4LRE A;  3Q3Q A;  5LIA A;  1ELY A;  4GTY A;  4UPK A;  1AJA A;  1E2S P;  3TX0 A;  5IJQ A;  4KJD A;  1N2L A;  4ZG9 A;  4UOO A;  4CYS A;  4MHX A;  4NWX A;  3A52 A;  2GSO A;  3NKR A;  3BDH A;  3SZZ A;  5L0B A;  2XRG A;  2IUC A;  3LXQ A;  1AJB A;  2G9Y A;  4LRB A;  1FSU A;  2W5R A;  1E3C P;  3IGZ B;  1E1Z P;  3SZY A;  3UN2 A;  4CXK A;  4NWJ A;  3IGY B;  4LRC A;  4CXS A;  3MK1 A;  3CMR A;  3UNY A;  1E33 P;  3OT9 A;  3MK2 A;  3NKO A;  1ZEB A;  2GLQ A;  2IFY A;  4UOR A;  5KXA A;  1ALJ A;  3M8Z A;  1EI6 A;  1EQJ A;  4KJG A;  1KHK A;  5L0K A;  2W5X A;  2D1G A;  4UPH A;  1ED8 A;  1KH9 A;  1Y6V A;  3T00 A;  1O98 A;  3UN3 A;  3NKN A;  3WAY A;  3NKQ A;  5INH A;  1HQA A;  2ANH A;  5L0E A;  1AJC A;  2W5V A;  3DPC A;  3ED4 A;  5GRR A;  2GSN A;  3NVL A;  1ALI A;  1HDH A;  1URA A;  1AJD A;  2IUC B;  4GTX A;  4LR8 A;  5IJS A;  1ED9 A;  1HJK A;  2RH6 A;  2W5W A;  3TG0 A;  2W5T A;  4LR2 A;  3WAX A;  1ELZ A;  4UOP A;  4CYR A;  5DLW A;  2QZU A;  1EW8 A;  2ZKT A;  5K4P A;  5DLV A;  4FDJ A;  4CXU A;  3M8W A;  1ALK A;  1O99 A;  1KH5 A;  2VQR A;  5EGE A;  5LQQ A;  3WAW A;  1N2K A;  2W8S A;  5TJ3 A;  1KH4 A;  4KM4 A;  4LRD A;  1KHL A;  1K7H A;  1ANJ A;  3UO0 A;  4GTW A;  4LRF A;  3MK0 A;  5C66 A;  2W5Q A;  3T02 A;  4LR7 A;  1EW2 A;  3B5Q A;  4ZG6 A;  3T01 A;  2W5S A;  3BDF A;  4MY4 A;  2GA3 A;  4TN0 A;  5LRN A;  3KD8 A;  4QAX A;  4N7T A;  1KHJ A;  1ZED A;  1URB A;  3E2D A;  3M8Y A;  4LQY A;  4MIV A;  1ANI A;  1B8J A;  1P49 A;  1ELX A;  3NKP A;  4UPL A;  2W8D A;  3BDG A;  3DYC A;  1EJJ A;  4KAY A;  3WBH A;  1SHQ A;  1KHN A;  1ALH A;  4UPI A;  5GOV A;  3TWZ A;  4ZG7 A;  2X98 A;  4KAV A;  5EGH A;  3WAV A;  5AJ9 A;  1Y7A A;  2XR9 A;  3NKM A;  5DLT A;  4YR1 A;  4LR9 A;  4ZGA A;  5LRM A; 
#chains in the Genus database with same CATH homology
 4LRA A;  3M7V A;  3IDD A;  5HRT A;  1AUK A;  1SHN A;  1EW9 A;  3UN5 A;  4GTZ A;  4B56 A;  4FDI A;  1KH7 A;  1ZEF A;  2GSU A;  3BDG B;  4LRE A;  3Q3Q A;  5LIA A;  1ELY A;  4GTY A;  4UPK A;  1AJA A;  1E2S P;  3TX0 A;  5IJQ A;  4KJD A;  1N2L A;  4ZG9 A;  4UOO A;  4CYS A;  4MHX A;  4NWX A;  3A52 A;  2GSO A;  3NKR A;  3BDH A;  3SZZ A;  5L0B A;  2XRG A;  2IUC A;  3LXQ A;  1AJB A;  2G9Y A;  4LRB A;  1FSU A;  2W5R A;  1E3C P;  3IGZ B;  1E1Z P;  3SZY A;  3UN2 A;  4CXK A;  4NWJ A;  3IGY B;  4LRC A;  4CXS A;  3MK1 A;  3CMR A;  3UNY A;  1E33 P;  3OT9 A;  3MK2 A;  3NKO A;  1ZEB A;  2GLQ A;  2IFY A;  4UOR A;  5KXA A;  1ALJ A;  3M8Z A;  1EI6 A;  1EQJ A;  4KJG A;  1KHK A;  5L0K A;  2W5X A;  2D1G A;  4UPH A;  1ED8 A;  1KH9 A;  1Y6V A;  3T00 A;  1O98 A;  3UN3 A;  3NKN A;  3WAY A;  3NKQ A;  5INH A;  1HQA A;  2ANH A;  5L0E A;  1AJC A;  2W5V A;  3DPC A;  3ED4 A;  5GRR A;  2GSN A;  3NVL A;  1ALI A;  1HDH A;  1URA A;  1AJD A;  2IUC B;  4GTX A;  4LR8 A;  5IJS A;  1ED9 A;  1HJK A;  2RH6 A;  2W5W A;  3TG0 A;  2W5T A;  4LR2 A;  3WAX A;  1ELZ A;  4UOP A;  4CYR A;  5DLW A;  2QZU A;  1EW8 A;  2ZKT A;  5K4P A;  5DLV A;  4FDJ A;  4CXU A;  3M8W A;  1ALK A;  1O99 A;  1KH5 A;  2VQR A;  5EGE A;  5LQQ A;  3WAW A;  1N2K A;  2W8S A;  5TJ3 A;  1KH4 A;  4KM4 A;  4LRD A;  1KHL A;  1K7H A;  1ANJ A;  3UO0 A;  4GTW A;  4LRF A;  3MK0 A;  5C66 A;  2W5Q A;  3T02 A;  4LR7 A;  1EW2 A;  3B5Q A;  4ZG6 A;  3T01 A;  2W5S A;  3BDF A;  4MY4 A;  2GA3 A;  4TN0 A;  5LRN A;  3KD8 A;  4QAX A;  4N7T A;  1KHJ A;  1ZED A;  1URB A;  3E2D A;  3M8Y A;  4LQY A;  4MIV A;  1ANI A;  1B8J A;  1P49 A;  1ELX A;  3NKP A;  4UPL A;  2W8D A;  3BDG A;  3DYC A;  1EJJ A;  4KAY A;  3WBH A;  1SHQ A;  1KHN A;  1ALH A;  4UPI A;  5GOV A;  3TWZ A;  4ZG7 A;  2X98 A;  4KAV A;  5EGH A;  3WAV A;  5AJ9 A;  1Y7A A;  2XR9 A;  3NKM A;  5DLT A;  4YR1 A;  4LR9 A;  4ZGA A;  5LRM A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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