5HE3G

Bovine grk2 in complex with gbetagamma subunits and ccg224411
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
58
structure length
58
Chain Sequence
TASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Bos taurus
molecule keywords Beta-adrenergic receptor kinase 1
total genus 14
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2016-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 5he3G00
2PBIA 5HE0G 1XHMB 5TDHG 5KDOG 1B9YB 1GP2G 3PSCG 3PVWG 3CIKG 3KRXG 3SN6G 5HE1G 1GOTG 3KRWG 4KFMG 4PNKG 2TRCG 1B9XB 4MK0G 3V5WG 5HE2G 1GG2G 5HE3G 2BCJG 1A0RG 1TBGE 3AH8G 3PVUG 1OMWG
chains in the Genus database with same CATH superfamily
2PBIA 5HE0G 1HFES 1XHMB 5TDHG 5KDOG 1B9YB 1GP2G 1IOJA 3PSCG 3PVWG 3CIKG 3KRXG 3SN6G 5HE1G 1GOTG 3KRWG 4KFMG 4PNKG 2TRCG 1B9XB 4MK0G 3V5WG 5HE2G 1GG2G 5HE3G 2BCJG 1A0RG 1TBGE 3AH8G 3PVUG 1OMWG
chains in the Genus database with same CATH topology
2PBIA 5HE0G 1XHMB 5TDHG 5KDOG 1B9YB 1GP2G 3PSCG 3PVWG 3CIKG 3KRXG 3SN6G 5HE1G 1GOTG 3KRWG 4KFMG 4PNKG 2TRCG 1B9XB 4MK0G 3V5WG 5HE2G 1GG2G 5HE3G 2BCJG 1A0RG 1TBGE 3AH8G 3PVUG 1OMWG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PBI A;  5HE0 G;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  1GP2 G;  3PSC G;  3PVW G;  3CIK G;  3KRX G;  3SN6 G;  5HE1 G;  1GOT G;  3KRW G;  4KFM G;  4PNK G;  2TRC G;  1B9X B;  4MK0 G;  3V5W G;  5HE2 G;  1GG2 G;  5HE3 G;  2BCJ G;  1A0R G;  1TBG E;  3AH8 G;  3PVU G;  1OMW G; 
#chains in the Genus database with same CATH topology
 2PBI A;  5HE0 G;  1HFE S;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  1GP2 G;  1IOJ A;  3PSC G;  3PVW G;  3CIK G;  3KRX G;  3SN6 G;  5HE1 G;  1GOT G;  3KRW G;  4KFM G;  4PNK G;  2TRC G;  1B9X B;  4MK0 G;  3V5W G;  5HE2 G;  1GG2 G;  5HE3 G;  2BCJ G;  1A0R G;  1TBG E;  3AH8 G;  3PVU G;  1OMW G; 
#chains in the Genus database with same CATH homology
 2PBI A;  5HE0 G;  1XHM B;  5TDH G;  5KDO G;  1B9Y B;  1GP2 G;  3PSC G;  3PVW G;  3CIK G;  3KRX G;  3SN6 G;  5HE1 G;  1GOT G;  3KRW G;  4KFM G;  4PNK G;  2TRC G;  1B9X B;  4MK0 G;  3V5W G;  5HE2 G;  1GG2 G;  5HE3 G;  2BCJ G;  1A0R G;  1TBG E;  3AH8 G;  3PVU G;  1OMW G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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