5HJAA

Crystal structure of leishmania mexicana arginase in complex with inhibitor abhdp
Total Genus 117
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
310
structure length
303
Chain Sequence
KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDNGDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLNDTISVGCAIARCMMGETLLYT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Arginase
publication title Crystal structures of Leishmania mexicana arginase complexed with alpha , alpha-disubstituted boronic amino-acid inhibitors.
pubmed doi rcsb
source organism Leishmania mexicana
molecule tags Hydrolase
total genus 117
structure length 303
sequence length 310
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2016-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 5hjaA00
1R1OA 1P8MA 2PHAA 3SKKA 4Q42A 1T4SA 4RHMA 1P8QA 1T4PA 4MYFA 1XFKA 4Q3UA 3DJ8A 1PQ3A 2EIVA 4Q3RA 1ZPEA 1GQ6A 5RLAA 2ZAVA 4Q3PA 4G3HA 1WOHA 1T5GA 1CEVA 3GMZA 4GSZA 4RHIA 4IE2A 4IXUA 3LP7A 4RHQA 2PLLA 3MFWA 2EF5A 4Q40A 1HQXA 1TBLA 4IU4A 1P8NA 4RHKA 4RHLA 3NIQA 3THJA 4IE1A 4RHJA 4HZEA 3LP4A 4Q3RC 1TBJA 4GWCA 3TH7A 3THHA 3SJTA 4IE3A 1WOGA 1P8PA 1P8OA 1HQ5A 4MYLA 1WVBA 1TA1A 3GN0A 4I06A 3PZLA 4HWWA 4Q41A 3MMRA 3NIOA 4CEVA 1TBHA 2RLAA 4GSVA 4Q3QA 4RLAA 3SL1A 4Q3VA 1T5FA 2CEVA 1HQGA 4MXRA 4GSMA 3TF3A 3E9BA 3LHLA 3NIPA 4ITYA 4IXVA 4IU0A 3THEA 1WOIA 5HJAA 3MJLA 3CEVA 4FCIA 4MYKA 1ZPGA 2A0MA 1HQFA 1WVAA 3SL0A 3E8QA 4FCKA 3MFVA 1GQ7A 5HJ9A 4MYNA 4Q3TA 4IU5A 1T4RA 3E8ZA 5CEVA 2AEBA 4HXQA 4GWDA 2PHOA 1T4TA 3KV2A 4DZ4A 3M1RA 4IU1A 1HQHA 1D3VA 1RLAA 1P8SA 2EF4A 4Q3SA 1P8RA 3E6VA 3F80A 3RLAA 3E6KA
chains in the Genus database with same CATH superfamily
1R1OA 1P8MA 2PHAA 3SKKA 4Q42A 1T4SA 4RN2A 5G0IA 1VKGA 4RHMA 1P8QA 5G3WA 1T4PA 2VQWG 4MYFA 1XFKA 5DC6A 3C0ZA 3MZ3A 3DJ8A 4Q3UA 3MZ7A 5G0HA 1PQ3A 5DC8A 2EIVA 4Q3RA 1ZPEA 2VQVA 1GQ6A 5RLAA 2ZAVA 4QA2A 4Q3PA 4G3HA 1WOHA 5DC7A 5EFNA 3Q9EA 1T5GA 1T67A 1CEVA 3GMZA 5FCWA 4GSZA 4RHIA 3F07A 4IE2A 4ZUMA 4IXUA 4CBYA 3LP7A 5EFKB 5G1CA 4RHQA 1T69A 2VQQA 3MAXA 2VCGA 2PLLA 5A2SA 3MFWA 2EF5A 3EWFA 3MENA 4Q40A 1HQXA 1TBLA 4IU4A 4QA4A 5G10A 1P8NA 5EF7A 4RHKA 1W22A 3NIQA 4RHLA 5FUEA 3THJA 4IE1A 4RHJA 5EFGA 5EENA 4BKXB 4BZ7A 4HZEA 3Q9BA 5JI5A 3LP4A 1T64A 4Q3RC 1TBJA 4GWCA 3TH7A 3THHA 3SJTA 5G0GA 3ZNRA 5G1AA 4IE3A 1WOGA 2VQMA 1P8PA 4QA3A 3F0RA 4QA0A 5ICNB 3RQDA 1P8OA 4ZUQA 1HQ5A 4MYLA 1WVBA 3C0YA 1TA1A 5EFHA 3GN0A 4I06A 4RN1A 5EEKA 3PZLA 4HWWA 4RN0A 4ZUPA 2V5WA 3MMRA 4ZURA 4BZ5A 3NIOA 5EEFA 4Q41A 5D1DA 4CEVA 5G13A 1TBHA 2RLAA 4GSVA 4Q3QA 2V5XA 4RLAA 5EFBD 4Q3VA 3SFFA 1ZZ3A 3SL1A 1C3PA 1T5FA 4ZUOA 2CEVA 3F06A 5G17A 5EFJD 1HQGA 4MXRA 5G1BA 4GSMA 3EZTA 5G11A 5IX0A 5THSA 4CBTA 3TF3A 3E9BA 3EZPA 3LHLA 3NIPA 4ITYA 3MZ4A 4IU0A 4IXVA 4LY1A 5DC5A 3C10A 4ZUNA 5G0YA 1ZZ0A 3THEA 4QA6A 2GH6A 3MZ6A 4LXZA 1WOIA 4A69A 5HJAA 5IWGA 3MJLA 3CEVA 5EF8A 5THVA 5LI3A 1C3RA 4FCIA 4MYKA 2VQOA 4BZ9A 4QA5A 1ZPGA 2A0MA 1HQFA 5THTA 1WVAA 3SL0A 3ZNSA 3E8QA 4FCKA 5EEMA 4CQFA 5G12A 3MFVA 1GQ7A 5HJ9A 4BZ8A 4MYNA 4Q3TA 2VQJA 4IU5A 4QA7A 1T4RA 5BWZA 3E8ZA 5CEVA 2AEBA 4HXQA 3Q9CA 5G0JA 3Q9FA 4GWDA 2PHOA 4QA1A 5EEIA 3EW8A 1T4TA 5THUA 4BZ6A 3KV2A 4DZ4A 3M1RA 5D1BA 4IU1A 1HQHA 1D3VA 1RLAA 1P8SA 2EF4A 4Q3SA 1P8RA 3E6VA 5D1CA 3F80A 1ZZ1A 5G0XA 3SFHA 3RLAA 1C3SA 3E6KA
chains in the Genus database with same CATH topology
1R1OA 1P8MA 2PHAA 3SKKA 4Q42A 1T4SA 4RHMA 1P8QA 1T4PA 4MYFA 1XFKA 4Q3UA 3DJ8A 1PQ3A 2EIVA 4Q3RA 1ZPEA 1GQ6A 5RLAA 2ZAVA 4Q3PA 4G3HA 1WOHA 1T5GA 1CEVA 3GMZA 4GSZA 4RHIA 4IE2A 4IXUA 3LP7A 4RHQA 2PLLA 3MFWA 2EF5A 4Q40A 1HQXA 1TBLA 4IU4A 1P8NA 4RHKA 4RHLA 3NIQA 3THJA 4IE1A 4RHJA 4HZEA 3LP4A 4Q3RC 1TBJA 4GWCA 3TH7A 3THHA 3SJTA 4IE3A 1WOGA 1P8PA 1P8OA 1HQ5A 4MYLA 1WVBA 1TA1A 3GN0A 4I06A 3PZLA 4HWWA 4Q41A 3MMRA 3NIOA 4CEVA 1TBHA 2RLAA 4GSVA 4Q3QA 4RLAA 3SL1A 4Q3VA 1T5FA 2CEVA 1HQGA 4MXRA 4GSMA 3TF3A 3E9BA 3LHLA 3NIPA 4ITYA 4IXVA 4IU0A 3THEA 1WOIA 5HJAA 3MJLA 3CEVA 4FCIA 4MYKA 1ZPGA 2A0MA 1HQFA 1WVAA 3SL0A 3E8QA 4FCKA 3MFVA 1GQ7A 5HJ9A 4MYNA 4Q3TA 4IU5A 1T4RA 3E8ZA 5CEVA 2AEBA 4HXQA 4GWDA 2PHOA 1T4TA 3KV2A 4DZ4A 3M1RA 4IU1A 1HQHA 1D3VA 1RLAA 1P8SA 2EF4A 4Q3SA 1P8RA 3E6VA 3F80A 3RLAA 3E6KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R1O A;  1P8M A;  2PHA A;  3SKK A;  4Q42 A;  1T4S A;  4RHM A;  1P8Q A;  1T4P A;  4MYF A;  1XFK A;  4Q3U A;  3DJ8 A;  1PQ3 A;  2EIV A;  4Q3R A;  1ZPE A;  1GQ6 A;  5RLA A;  2ZAV A;  4Q3P A;  4G3H A;  1WOH A;  1T5G A;  1CEV A;  3GMZ A;  4GSZ A;  4RHI A;  4IE2 A;  4IXU A;  3LP7 A;  4RHQ A;  2PLL A;  3MFW A;  2EF5 A;  4Q40 A;  1HQX A;  1TBL A;  4IU4 A;  1P8N A;  4RHK A;  4RHL A;  3NIQ A;  3THJ A;  4IE1 A;  4RHJ A;  4HZE A;  3LP4 A;  4Q3R C;  1TBJ A;  4GWC A;  3TH7 A;  3THH A;  3SJT A;  4IE3 A;  1WOG A;  1P8P A;  1P8O A;  1HQ5 A;  4MYL A;  1WVB A;  1TA1 A;  3GN0 A;  4I06 A;  3PZL A;  4HWW A;  4Q41 A;  3MMR A;  3NIO A;  4CEV A;  1TBH A;  2RLA A;  4GSV A;  4Q3Q A;  4RLA A;  3SL1 A;  4Q3V A;  1T5F A;  2CEV A;  1HQG A;  4MXR A;  4GSM A;  3TF3 A;  3E9B A;  3LHL A;  3NIP A;  4ITY A;  4IXV A;  4IU0 A;  3THE A;  1WOI A;  5HJA A;  3MJL A;  3CEV A;  4FCI A;  4MYK A;  1ZPG A;  2A0M A;  1HQF A;  1WVA A;  3SL0 A;  3E8Q A;  4FCK A;  3MFV A;  1GQ7 A;  5HJ9 A;  4MYN A;  4Q3T A;  4IU5 A;  1T4R A;  3E8Z A;  5CEV A;  2AEB A;  4HXQ A;  4GWD A;  2PHO A;  1T4T A;  3KV2 A;  4DZ4 A;  3M1R A;  4IU1 A;  1HQH A;  1D3V A;  1RLA A;  1P8S A;  2EF4 A;  4Q3S A;  1P8R A;  3E6V A;  3F80 A;  3RLA A;  3E6K A; 
#chains in the Genus database with same CATH topology
 1R1O A;  1P8M A;  2PHA A;  3SKK A;  4Q42 A;  1T4S A;  4RN2 A;  5G0I A;  1VKG A;  4RHM A;  1P8Q A;  5G3W A;  1T4P A;  2VQW G;  4MYF A;  1XFK A;  5DC6 A;  3C0Z A;  3MZ3 A;  3DJ8 A;  4Q3U A;  3MZ7 A;  5G0H A;  1PQ3 A;  5DC8 A;  2EIV A;  4Q3R A;  1ZPE A;  2VQV A;  1GQ6 A;  5RLA A;  2ZAV A;  4QA2 A;  4Q3P A;  4G3H A;  1WOH A;  5DC7 A;  5EFN A;  3Q9E A;  1T5G A;  1T67 A;  1CEV A;  3GMZ A;  5FCW A;  4GSZ A;  4RHI A;  3F07 A;  4IE2 A;  4ZUM A;  4IXU A;  4CBY A;  3LP7 A;  5EFK B;  5G1C A;  4RHQ A;  1T69 A;  2VQQ A;  3MAX A;  2VCG A;  2PLL A;  5A2S A;  3MFW A;  2EF5 A;  3EWF A;  3MEN A;  4Q40 A;  1HQX A;  1TBL A;  4IU4 A;  4QA4 A;  5G10 A;  1P8N A;  5EF7 A;  4RHK A;  1W22 A;  3NIQ A;  4RHL A;  5FUE A;  3THJ A;  4IE1 A;  4RHJ A;  5EFG A;  5EEN A;  4BKX B;  4BZ7 A;  4HZE A;  3Q9B A;  5JI5 A;  3LP4 A;  1T64 A;  4Q3R C;  1TBJ A;  4GWC A;  3TH7 A;  3THH A;  3SJT A;  5G0G A;  3ZNR A;  5G1A A;  4IE3 A;  1WOG A;  2VQM A;  1P8P A;  4QA3 A;  3F0R A;  4QA0 A;  5ICN B;  3RQD A;  1P8O A;  4ZUQ A;  1HQ5 A;  4MYL A;  1WVB A;  3C0Y A;  1TA1 A;  5EFH A;  3GN0 A;  4I06 A;  4RN1 A;  5EEK A;  3PZL A;  4HWW A;  4RN0 A;  4ZUP A;  2V5W A;  3MMR A;  4ZUR A;  4BZ5 A;  3NIO A;  5EEF A;  4Q41 A;  5D1D A;  4CEV A;  5G13 A;  1TBH A;  2RLA A;  4GSV A;  4Q3Q A;  2V5X A;  4RLA A;  5EFB D;  4Q3V A;  3SFF A;  1ZZ3 A;  3SL1 A;  1C3P A;  1T5F A;  4ZUO A;  2CEV A;  3F06 A;  5G17 A;  5EFJ D;  1HQG A;  4MXR A;  5G1B A;  4GSM A;  3EZT A;  5G11 A;  5IX0 A;  5THS A;  4CBT A;  3TF3 A;  3E9B A;  3EZP A;  3LHL A;  3NIP A;  4ITY A;  3MZ4 A;  4IU0 A;  4IXV A;  4LY1 A;  5DC5 A;  3C10 A;  4ZUN A;  5G0Y A;  1ZZ0 A;  3THE A;  4QA6 A;  2GH6 A;  3MZ6 A;  4LXZ A;  1WOI A;  4A69 A;  5HJA A;  5IWG A;  3MJL A;  3CEV A;  5EF8 A;  5THV A;  5LI3 A;  1C3R A;  4FCI A;  4MYK A;  2VQO A;  4BZ9 A;  4QA5 A;  1ZPG A;  2A0M A;  1HQF A;  5THT A;  1WVA A;  3SL0 A;  3ZNS A;  3E8Q A;  4FCK A;  5EEM A;  4CQF A;  5G12 A;  3MFV A;  1GQ7 A;  5HJ9 A;  4BZ8 A;  4MYN A;  4Q3T A;  2VQJ A;  4IU5 A;  4QA7 A;  1T4R A;  5BWZ A;  3E8Z A;  5CEV A;  2AEB A;  4HXQ A;  3Q9C A;  5G0J A;  3Q9F A;  4GWD A;  2PHO A;  4QA1 A;  5EEI A;  3EW8 A;  1T4T A;  5THU A;  4BZ6 A;  3KV2 A;  4DZ4 A;  3M1R A;  5D1B A;  4IU1 A;  1HQH A;  1D3V A;  1RLA A;  1P8S A;  2EF4 A;  4Q3S A;  1P8R A;  3E6V A;  5D1C A;  3F80 A;  1ZZ1 A;  5G0X A;  3SFH A;  3RLA A;  1C3S A;  3E6K A; 
#chains in the Genus database with same CATH homology
 1R1O A;  1P8M A;  2PHA A;  3SKK A;  4Q42 A;  1T4S A;  4RHM A;  1P8Q A;  1T4P A;  4MYF A;  1XFK A;  4Q3U A;  3DJ8 A;  1PQ3 A;  2EIV A;  4Q3R A;  1ZPE A;  1GQ6 A;  5RLA A;  2ZAV A;  4Q3P A;  4G3H A;  1WOH A;  1T5G A;  1CEV A;  3GMZ A;  4GSZ A;  4RHI A;  4IE2 A;  4IXU A;  3LP7 A;  4RHQ A;  2PLL A;  3MFW A;  2EF5 A;  4Q40 A;  1HQX A;  1TBL A;  4IU4 A;  1P8N A;  4RHK A;  4RHL A;  3NIQ A;  3THJ A;  4IE1 A;  4RHJ A;  4HZE A;  3LP4 A;  4Q3R C;  1TBJ A;  4GWC A;  3TH7 A;  3THH A;  3SJT A;  4IE3 A;  1WOG A;  1P8P A;  1P8O A;  1HQ5 A;  4MYL A;  1WVB A;  1TA1 A;  3GN0 A;  4I06 A;  3PZL A;  4HWW A;  4Q41 A;  3MMR A;  3NIO A;  4CEV A;  1TBH A;  2RLA A;  4GSV A;  4Q3Q A;  4RLA A;  3SL1 A;  4Q3V A;  1T5F A;  2CEV A;  1HQG A;  4MXR A;  4GSM A;  3TF3 A;  3E9B A;  3LHL A;  3NIP A;  4ITY A;  4IXV A;  4IU0 A;  3THE A;  1WOI A;  5HJA A;  3MJL A;  3CEV A;  4FCI A;  4MYK A;  1ZPG A;  2A0M A;  1HQF A;  1WVA A;  3SL0 A;  3E8Q A;  4FCK A;  3MFV A;  1GQ7 A;  5HJ9 A;  4MYN A;  4Q3T A;  4IU5 A;  1T4R A;  3E8Z A;  5CEV A;  2AEB A;  4HXQ A;  4GWD A;  2PHO A;  1T4T A;  3KV2 A;  4DZ4 A;  3M1R A;  4IU1 A;  1HQH A;  1D3V A;  1RLA A;  1P8S A;  2EF4 A;  4Q3S A;  1P8R A;  3E6V A;  3F80 A;  3RLA A;  3E6K A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...