5HL7E

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
157
structure length
157
Chain Sequence
TFDGNHVTVKGPKGELSRTLNERMTFKQEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKDLILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGKGIRYQGEYVRRKEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 17
structure length 157
sequence length 157
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00347 Ribosomal_L6 Ribosomal protein L6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 5hl7E02
3.90.930.12 Alpha Beta Alpha-Beta Complex Outer Surface Protein A; domain 3 Ribosomal protein L6, alpha-beta domain 5hl7E01
1K73G 1YJNE 3G71E 1VQ8E 5HL7E 4WFBE 1VQLE 1QVGE 1M90G 3CCEE 4IOCE 1JJ2E 1VQNE 5H1SI 1YITE 3PIPE 3CCUE 4WCEE 2CQLA 4IO9E 3G6EE 1VQPE 5DM6E 1Q82G 1S72E 1YI2E 3G4SE 1K9MG 3CCQE 3CMEE 3CMAE 3CF5E 3CC7E 2ZJRE 1VQ7E 3PIOE 3CCME 3J7ZG 1VQ4E 1QVFE 1NJIG 3CCJE 4IOAE 1KC8G 1Q86G 4WFNE 1M1KG 5GADG 3DLLE 5GAGG 5JVGE 5GAHG 1RL6A 3CCSE 3CXCE 1YHQE 3I56E 3CCVE 5JVHE 1W2BE 3CCLE 2ZJPE 1YJWE 2OTLE 3CC2E 1Q7YG 3CD6E 1VQ9E 3OW2E 3CPWE 1K8AG 1YIJE 1YJ9E 2QEXE 5GAEG 3CCRE 1VQKE 5DM7E 2OTJE 1VQ6E 2ZJQE 4WF9E 3I55E 1VQOE 5AN9B 1KD1G 1Q81G 1VQ5E 1N8RG 4WFAE 1KQSE 2QA4E 1VQME 4UY8G 4U67E 5MLCH 3CC4E
chains in the Genus database with same CATH superfamily
2I5ZO 2FKJA 1K73G 1YJNE 3G71E 2AF5A 1VQ8E 2OY5O 5HL7E 4WFBE 1VQLE 1QVGE 1M90G 3CCEE 4IOCE 1JJ2E 1VQNE 5H1SI 1YITE 5B2AO 3PIPE 3CCUE 4WCEE 2CQLA 4IO9E 3G6EE 1VQPE 5DM6E 1Q82G 1S72E 1YI2E 3G4SE 1K9MG 5B11O 3CCQE 3CMEE 3CMAE 3CF5E 2PI3O 3CC7E 2ZJRE 1VQ7E 3PIOE 1OSPO 3CCME 5B10O 3J7ZG 1VQ4E 1QVFE 1NJIG 3CCJE 4IOAE 3IGEA 1KC8G 1Q86G 4WFNE 1M1KG 2I5VO 2OL6O 5GADG 3DLLE 5GAGG 5JVGE 2FKGA 5GAHG 1RL6A 2OL7A 3CCSE 3CXCE 1YHQE 3I56E 3CCVE 5JVHE 1W2BE 3CCLE 3CKFA 2ZJPE 1YJWE 2OTLE 3CC2E 1Q7YG 3CD6E 1VQ9E 3OW2E 2OY1O 2OY7A 3CPWE 1K8AG 1YIJE 1YJ9E 3IG9A 5GAEG 2QEXE 2OYBO 3CCRE 1VQKE 5DM7E 2OTJE 5B3MO 2OY8A 1VQ6E 2ZJQE 4WF9E 3I55E 3CKGA 1VQOE 2HKDA 5AN9B 1KD1G 1Q81G 1VQ5E 3AUMO 1N8RG 4WFAE 2OL8O 1KQSE 1FJ1E 2QA4E 3EC5A 1VQME 1P4PA 4UY8G 2G8CO 4U67E 5MLCH 1RJLC 3CC4E
chains in the Genus database with same CATH topology
1K73G 1YJNE 3G71E 1VQ8E 5HL7E 4WFBE 1VQLE 1QVGE 1M90G 3CCEE 4IOCE 1JJ2E 1VQNE 5H1SI 1YITE 3PIPE 3CCUE 4WCEE 2CQLA 4IO9E 3G6EE 1VQPE 5DM6E 1Q82G 1S72E 1YI2E 3G4SE 1K9MG 3CCQE 3CMEE 3CMAE 3CF5E 3CC7E 2ZJRE 1VQ7E 3PIOE 3CCME 3J7ZG 1VQ4E 1QVFE 1NJIG 3CCJE 4IOAE 1KC8G 1Q86G 4WFNE 1M1KG 5GADG 3DLLE 5GAGG 5JVGE 5GAHG 1RL6A 3CCSE 3CXCE 1YHQE 3I56E 3CCVE 5JVHE 1W2BE 3CCLE 2ZJPE 1YJWE 2OTLE 3CC2E 1Q7YG 3CD6E 1VQ9E 3OW2E 3CPWE 1K8AG 1YIJE 1YJ9E 2QEXE 5GAEG 3CCRE 1VQKE 5DM7E 2OTJE 1VQ6E 2ZJQE 4WF9E 3I55E 1VQOE 5AN9B 1KD1G 1Q81G 1VQ5E 1N8RG 4WFAE 1KQSE 2QA4E 1VQME 4UY8G 4U67E 5MLCH 3CC4E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K73 G;  1YJN E;  3G71 E;  1VQ8 E;  5HL7 E;  4WFB E;  1VQL E;  1QVG E;  1M90 G;  3CCE E;  4IOC E;  1JJ2 E;  1VQN E;  5H1S I;  1YIT E;  3PIP E;  3CCU E;  4WCE E;  2CQL A;  4IO9 E;  3G6E E;  1VQP E;  5DM6 E;  1Q82 G;  1S72 E;  1YI2 E;  3G4S E;  1K9M G;  3CCQ E;  3CME E;  3CMA E;  3CF5 E;  3CC7 E;  2ZJR E;  1VQ7 E;  3PIO E;  3CCM E;  3J7Z G;  1VQ4 E;  1QVF E;  1NJI G;  3CCJ E;  4IOA E;  1KC8 G;  1Q86 G;  4WFN E;  1M1K G;  5GAD G;  3DLL E;  5GAG G;  5JVG E;  5GAH G;  1RL6 A;  3CCS E;  3CXC E;  1YHQ E;  3I56 E;  3CCV E;  5JVH E;  1W2B E;  3CCL E;  2ZJP E;  1YJW E;  2OTL E;  3CC2 E;  1Q7Y G;  3CD6 E;  1VQ9 E;  3OW2 E;  3CPW E;  1K8A G;  1YIJ E;  1YJ9 E;  2QEX E;  5GAE G;  3CCR E;  1VQK E;  5DM7 E;  2OTJ E;  1VQ6 E;  2ZJQ E;  4WF9 E;  3I55 E;  1VQO E;  5AN9 B;  1KD1 G;  1Q81 G;  1VQ5 E;  1N8R G;  4WFA E;  1KQS E;  2QA4 E;  1VQM E;  4UY8 G;  4U67 E;  5MLC H;  3CC4 E; 
#chains in the Genus database with same CATH topology
 2I5Z O;  2FKJ A;  1K73 G;  1YJN E;  3G71 E;  2AF5 A;  1VQ8 E;  2OY5 O;  5HL7 E;  4WFB E;  1VQL E;  1QVG E;  1M90 G;  3CCE E;  4IOC E;  1JJ2 E;  1VQN E;  5H1S I;  1YIT E;  5B2A O;  3PIP E;  3CCU E;  4WCE E;  2CQL A;  4IO9 E;  3G6E E;  1VQP E;  5DM6 E;  1Q82 G;  1S72 E;  1YI2 E;  3G4S E;  1K9M G;  5B11 O;  3CCQ E;  3CME E;  3CMA E;  3CF5 E;  2PI3 O;  3CC7 E;  2ZJR E;  1VQ7 E;  3PIO E;  1OSP O;  3CCM E;  5B10 O;  3J7Z G;  1VQ4 E;  1QVF E;  1NJI G;  3CCJ E;  4IOA E;  3IGE A;  1KC8 G;  1Q86 G;  4WFN E;  1M1K G;  2I5V O;  2OL6 O;  5GAD G;  3DLL E;  5GAG G;  5JVG E;  2FKG A;  5GAH G;  1RL6 A;  2OL7 A;  3CCS E;  3CXC E;  1YHQ E;  3I56 E;  3CCV E;  5JVH E;  1W2B E;  3CCL E;  3CKF A;  2ZJP E;  1YJW E;  2OTL E;  3CC2 E;  1Q7Y G;  3CD6 E;  1VQ9 E;  3OW2 E;  2OY1 O;  2OY7 A;  3CPW E;  1K8A G;  1YIJ E;  1YJ9 E;  3IG9 A;  5GAE G;  2QEX E;  2OYB O;  3CCR E;  1VQK E;  5DM7 E;  2OTJ E;  5B3M O;  2OY8 A;  1VQ6 E;  2ZJQ E;  4WF9 E;  3I55 E;  3CKG A;  1VQO E;  2HKD A;  5AN9 B;  1KD1 G;  1Q81 G;  1VQ5 E;  3AUM O;  1N8R G;  4WFA E;  2OL8 O;  1KQS E;  1FJ1 E;  2QA4 E;  3EC5 A;  1VQM E;  1P4P A;  4UY8 G;  2G8C O;  4U67 E;  5MLC H;  1RJL C;  3CC4 E; 
#chains in the Genus database with same CATH homology
 1K73 G;  1YJN E;  3G71 E;  1VQ8 E;  5HL7 E;  4WFB E;  1VQL E;  1QVG E;  1M90 G;  3CCE E;  4IOC E;  1JJ2 E;  1VQN E;  5H1S I;  1YIT E;  3PIP E;  3CCU E;  4WCE E;  2CQL A;  4IO9 E;  3G6E E;  1VQP E;  5DM6 E;  1Q82 G;  1S72 E;  1YI2 E;  3G4S E;  1K9M G;  3CCQ E;  3CME E;  3CMA E;  3CF5 E;  3CC7 E;  2ZJR E;  1VQ7 E;  3PIO E;  3CCM E;  3J7Z G;  1VQ4 E;  1QVF E;  1NJI G;  3CCJ E;  4IOA E;  1KC8 G;  1Q86 G;  4WFN E;  1M1K G;  5GAD G;  3DLL E;  5GAG G;  5JVG E;  5GAH G;  1RL6 A;  3CCS E;  3CXC E;  1YHQ E;  3I56 E;  3CCV E;  5JVH E;  1W2B E;  3CCL E;  2ZJP E;  1YJW E;  2OTL E;  3CC2 E;  1Q7Y G;  3CD6 E;  1VQ9 E;  3OW2 E;  3CPW E;  1K8A G;  1YIJ E;  1YJ9 E;  2QEX E;  5GAE G;  3CCR E;  1VQK E;  5DM7 E;  2OTJ E;  1VQ6 E;  2ZJQ E;  4WF9 E;  3I55 E;  1VQO E;  5AN9 B;  1KD1 G;  1Q81 G;  1VQ5 E;  1N8R G;  4WFA E;  1KQS E;  2QA4 E;  1VQM E;  4UY8 G;  4U67 E;  5MLC H;  3CC4 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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