5HL7S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
167
structure length
167
Chain Sequence
b'SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 50S ribosomal protein L2
publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
total genus 22
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5hl7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5hl7S02
3DLLS 4IO9S 1O0BA 4JXXA 1QRUA 3J7ZV 3AIIA 2ZJRS 4WFBS 2ZJPS 5HL7S 1QRSA 1FEUA 1EUQA 3CF5S 1O0CA 5JVGS 4U67S 5GAGW 5IZNA 1GTSA 1QRTA 3PIOS 4WF9S 2HZ7A 5JVHS 1B75A 1ZJWA 5GAEW 5BNZA 4IOAS 4IOCS 1DFUP 5DM6S 5GAHW 1QTQA 4UY88 4WFAS 1D6KA 4P2BA 1EXDA 4JXZA 5GADW 3PIPS 2RD2A 2RE8A 4WFNS 1EUYA 4WCES 1GTRA 4H3SA 2ZJQS 1NYLA 4JYZA 5DM7S
chains in the Genus database with same CATH superfamily
3LYWA 1BDFA 2Y0SD 4A3DC 2R92C 1Y1WC 1O0BA 3GTJC 4AYBD 3AIIA 4A3GC 2ZJPS 1FEUA 4XSZA 2JA5C 1IW7A 3HOXC 2CX8A 1VHYA 4BXXC 3EQLA 4A93C 2NWAA 3X1LB 2JA7C 3GTKC 1I6VA 4Y52C 3HOZC 4YFNA 4YG2A 2YU9C 1Z85A 2WB1D 5GAEW 3RZOC 2PICA 4C3HC 5DM6S 2EGWA 2KPUA 3HOWC 5HQHA 4P2BA 5TMFA 5TMCA 3K7AC 3S1RC 3S14C 4H4KA 2PMZD 4Q4ZA 2PJJA 2G6GA 4WCES 1V6ZA 4H3SA 3I4NC 3S1NC 4MEXA 4JYZA 4OIQA 4IO9S 4KMUA 4A3KC 4JXXA 2ZJRS 4LK1A 1I3QC 3GTLC 2A6HA 1HQMA 4OIRA 4A3IC 3GTPC 4V194 4JK1A 3HOVC 2O5JA 4X6AC 2PI8A 1I6HC 1SMYA 5GAGW 4E8BA 4XSXA 2L3UA 2KQ1A 5IZNA 1QRTA 4C3IC 2JA6C 4OIPA 4MEYA 4WF9S 3GTMC 3FKIC 3GTGC 4G7HA 2AE0X 5BNZA 4IOAS 2NVQC 4A3CC 2G5DA 1SFOC 2PNWA 1Y1VC 4J3CA 4XLNA 3CZBA 1QTQA 4UY88 5FLMC 4WFAS 4G7OA 2NVYC 2EGVA 1TWGC 4YFXA 2R7ZC 3PIPS 2WAQD 4LLGA 4QJVA 2RE8A 4WFNS 1EUYA 1TWCC 1I50C 3H3VD 1TWFC 5IYCC 3I4MC 1WCMC 5IYDC 4A3BC 1R9TC 1QRUA 3CQZC 2A68A 3W2WB 1QRSA 4LK0A 1O0CA 3S1MC 2B63C 3PO3C 4U67S 2E2HC 1ZYRA 2BE5A 4A3LC 3S15C 3PIOS 4GZYA 2HZ7A 4ZH4A 1B75A 3HOUC 3S2DC 2R93C 4IOCS 1DFUP 4G7ZA 3M4OC 3H0GC 2GAEA 1NXZA 1TWAC 1D6KA 2A69A 1EXDA 4A3FC 1K83C 5C4JC 3W2VB 3S2HC 4YFKA 1YNJA 4MQ9A 1GTRA 1VHKA 3WODA 2NVXC 5IYBC 3KW2A 3DXJA 1NYLA 3HKZD 4A3JC 3RZDC 4BY1C 3S16C 4OIOA 3DLLS 5C44C 5IP7C 1YNNA 2A6EA 3J7ZV 2KXYA 4WFBS 2PPBA 5HL7S 3HOYC 1EUQA 1UDXA 3CF5S 2O5IA 4BBRC 5JVGS 3PO2C 4C2MC 2CW0A 2VUMC 4NOIA 5IP9C 1GTSA 3GTQC 2Z0YA 5JVHS 1ZJWA 4XLPA 2L5NA 2PA8D 4Q5SA 2NVTC 4A3MC 4BBSC 5GAHW 3GTOC 4Y7NC 4QIWD 3S17C 4L69A 3M3YC 4KN7A 5C4XC 1TWHC 4JXZA 4OINA 5GADW 2E2JC 4BY7C 5D4DA 2RD2A 4LJZA 4KN4A 3S1QC 4A3EC 2E2IC 5C3EC 2ZJQS 5DM7S 4C3JC 2JA8C
chains in the Genus database with same CATH topology
3DLLS 4IO9S 1O0BA 4JXXA 1QRUA 3J7ZV 3AIIA 2ZJRS 4WFBS 2ZJPS 3W2WB 5HL7S 1QRSA 1FEUA 1EUQA 1UDXA 3CF5S 1O0CA 5JVGS 4V194 4U67S 5GAGW 3X1LB 5IZNA 1GTSA 1QRTA 3PIOS 4WF9S 2HZ7A 5JVHS 1B75A 1ZJWA 5GAEW 5BNZA 4IOAS 4IOCS 1DFUP 5DM6S 5GAHW 1QTQA 4UY88 4WFAS 1D6KA 4P2BA 1EXDA 4JXZA 4H4KA 5GADW 3W2VB 3PIPS 2RD2A 2RE8A 4WFNS 1EUYA 4WCES 1GTRA 4H3SA 2ZJQS 1NYLA 4JYZA 5DM7S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DLL S;  4IO9 S;  1O0B A;  4JXX A;  1QRU A;  3J7Z V;  3AII A;  2ZJR S;  4WFB S;  2ZJP S;  5HL7 S;  1QRS A;  1FEU A;  1EUQ A;  3CF5 S;  1O0C A;  5JVG S;  4U67 S;  5GAG W;  5IZN A;  1GTS A;  1QRT A;  3PIO S;  4WF9 S;  2HZ7 A;  5JVH S;  1B75 A;  1ZJW A;  5GAE W;  5BNZ A;  4IOA S;  4IOC S;  1DFU P;  5DM6 S;  5GAH W;  1QTQ A;  4UY8 8;  4WFA S;  1D6K A;  4P2B A;  1EXD A;  4JXZ A;  5GAD W;  3PIP S;  2RD2 A;  2RE8 A;  4WFN S;  1EUY A;  4WCE S;  1GTR A;  4H3S A;  2ZJQ S;  1NYL A;  4JYZ A;  5DM7 S; 
#chains in the Genus database with same CATH topology
 3LYW A;  1BDF A;  2Y0S D;  4A3D C;  2R92 C;  1Y1W C;  1O0B A;  3GTJ C;  4AYB D;  3AII A;  4A3G C;  2ZJP S;  1FEU A;  4XSZ A;  2JA5 C;  1IW7 A;  3HOX C;  2CX8 A;  1VHY A;  4BXX C;  3EQL A;  4A93 C;  2NWA A;  3X1L B;  2JA7 C;  3GTK C;  1I6V A;  4Y52 C;  3HOZ C;  4YFN A;  4YG2 A;  2YU9 C;  1Z85 A;  2WB1 D;  5GAE W;  3RZO C;  2PIC A;  4C3H C;  5DM6 S;  2EGW A;  2KPU A;  3HOW C;  5HQH A;  4P2B A;  5TMF A;  5TMC A;  3K7A C;  3S1R C;  3S14 C;  4H4K A;  2PMZ D;  4Q4Z A;  2PJJ A;  2G6G A;  4WCE S;  1V6Z A;  4H3S A;  3I4N C;  3S1N C;  4MEX A;  4JYZ A;  4OIQ A;  4IO9 S;  4KMU A;  4A3K C;  4JXX A;  2ZJR S;  4LK1 A;  1I3Q C;  3GTL C;  2A6H A;  1HQM A;  4OIR A;  4A3I C;  3GTP C;  4V19 4;  4JK1 A;  3HOV C;  2O5J A;  4X6A C;  2PI8 A;  1I6H C;  1SMY A;  5GAG W;  4E8B A;  4XSX A;  2L3U A;  2KQ1 A;  5IZN A;  1QRT A;  4C3I C;  2JA6 C;  4OIP A;  4MEY A;  4WF9 S;  3GTM C;  3FKI C;  3GTG C;  4G7H A;  2AE0 X;  5BNZ A;  4IOA S;  2NVQ C;  4A3C C;  2G5D A;  1SFO C;  2PNW A;  1Y1V C;  4J3C A;  4XLN A;  3CZB A;  1QTQ A;  4UY8 8;  5FLM C;  4WFA S;  4G7O A;  2NVY C;  2EGV A;  1TWG C;  4YFX A;  2R7Z C;  3PIP S;  2WAQ D;  4LLG A;  4QJV A;  2RE8 A;  4WFN S;  1EUY A;  1TWC C;  1I50 C;  3H3V D;  1TWF C;  5IYC C;  3I4M C;  1WCM C;  5IYD C;  4A3B C;  1R9T C;  1QRU A;  3CQZ C;  2A68 A;  3W2W B;  1QRS A;  4LK0 A;  1O0C A;  3S1M C;  2B63 C;  3PO3 C;  4U67 S;  2E2H C;  1ZYR A;  2BE5 A;  4A3L C;  3S15 C;  3PIO S;  4GZY A;  2HZ7 A;  4ZH4 A;  1B75 A;  3HOU C;  3S2D C;  2R93 C;  4IOC S;  1DFU P;  4G7Z A;  3M4O C;  3H0G C;  2GAE A;  1NXZ A;  1TWA C;  1D6K A;  2A69 A;  1EXD A;  4A3F C;  1K83 C;  5C4J C;  3W2V B;  3S2H C;  4YFK A;  1YNJ A;  4MQ9 A;  1GTR A;  1VHK A;  3WOD A;  2NVX C;  5IYB C;  3KW2 A;  3DXJ A;  1NYL A;  3HKZ D;  4A3J C;  3RZD C;  4BY1 C;  3S16 C;  4OIO A;  3DLL S;  5C44 C;  5IP7 C;  1YNN A;  2A6E A;  3J7Z V;  2KXY A;  4WFB S;  2PPB A;  5HL7 S;  3HOY C;  1EUQ A;  1UDX A;  3CF5 S;  2O5I A;  4BBR C;  5JVG S;  3PO2 C;  4C2M C;  2CW0 A;  2VUM C;  4NOI A;  5IP9 C;  1GTS A;  3GTQ C;  2Z0Y A;  5JVH S;  1ZJW A;  4XLP A;  2L5N A;  2PA8 D;  4Q5S A;  2NVT C;  4A3M C;  4BBS C;  5GAH W;  3GTO C;  4Y7N C;  4QIW D;  3S17 C;  4L69 A;  3M3Y C;  4KN7 A;  5C4X C;  1TWH C;  4JXZ A;  4OIN A;  5GAD W;  2E2J C;  4BY7 C;  5D4D A;  2RD2 A;  4LJZ A;  4KN4 A;  3S1Q C;  4A3E C;  2E2I C;  5C3E C;  2ZJQ S;  5DM7 S;  4C3J C;  2JA8 C; 
#chains in the Genus database with same CATH homology
 3DLL S;  4IO9 S;  1O0B A;  4JXX A;  1QRU A;  3J7Z V;  3AII A;  2ZJR S;  4WFB S;  2ZJP S;  3W2W B;  5HL7 S;  1QRS A;  1FEU A;  1EUQ A;  1UDX A;  3CF5 S;  1O0C A;  5JVG S;  4V19 4;  4U67 S;  5GAG W;  3X1L B;  5IZN A;  1GTS A;  1QRT A;  3PIO S;  4WF9 S;  2HZ7 A;  5JVH S;  1B75 A;  1ZJW A;  5GAE W;  5BNZ A;  4IOA S;  4IOC S;  1DFU P;  5DM6 S;  5GAH W;  1QTQ A;  4UY8 8;  4WFA S;  1D6K A;  4P2B A;  1EXD A;  4JXZ A;  4H4K A;  5GAD W;  3W2V B;  3PIP S;  2RD2 A;  2RE8 A;  4WFN S;  1EUY A;  4WCE S;  1GTR A;  4H3S A;  2ZJQ S;  1NYL A;  4JYZ A;  5DM7 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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