5HL7S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 50S ribosomal protein L2
publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
total genus 22
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5hl7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5hl7S02
1ZJWA 3AIIA 2ZJPS 5JVGS 5IZNA 4JXZA 4P2BA 5BNZA 4JYZA 5GAHW 1GTSA 3PIOS 1QRSA 4U67S 1O0CA 3CF5S 4IO9S 4IOCS 4WF9S 1NYLA 2ZJQS 2RD2A 1EUYA 1QRUA 4UY88 1DFUP 5GADW 3PIPS 3J7ZV 4JXXA 4WFAS 1GTRA 1QTQA 1FEUA 2ZJRS 3DLLS 4WFBS 5JVHS 4IOAS 4H3SA 1EXDA 5GAEW 5HL7S 1B75A 2HZ7A 5GAGW 4WFNS 5DM6S 2RE8A 1D6KA 1EUQA 1O0BA 1QRTA 4WCES 5DM7S
chains in the Genus database with same CATH superfamily
1I6HC 1UDXA 3CZBA 4MQ9A 3X1LB 4YFNA 4ZH4A 5IYBC 4A3MC 3HOYC 4JYZA 5GAHW 1GTSA 3PIOS 4YG2A 2O5IA 3S2DC 4U67S 3W2WB 1I6VA 4OIOA 4WF9S 4J3CA 3S1RC 4L69A 4AYBD 2G6GA 2PA8D 4MEXA 4KN4A 4XLPA 1QTQA 2NVQC 1BDFA 1TWCC 3S1MC 1VHKA 3DLLS 2JA5C 4IOAS 3S16C 3GTLC 1HQMA 5GAEW 5D4DA 3I4NC 4X6AC 2PICA 2AE0X 4BY7C 2A6HA 2PJJA 4OINA 2JA8C 5GAGW 2RE8A 2G5DA 4A3KC 4XSZA 5TMFA 1SMYA 3DXJA 1ZJWA 3AIIA 3H0GC 3M3YC 5IZNA 4NOIA 1NXZA 4JXZA 3HOZC 4H4KA 3S14C 2NVTC 3CQZC 4KMUA 1ZYRA 2NWAA 4YFXA 2R93C 3CF5S 3HOVC 2O5JA 2ZJQS 4Y52C 1V6ZA 3PIPS 2BE5A 3J7ZV 4C2MC 4JXXA 3GTMC 1GTRA 1FEUA 3PO2C 2ZJRS 2A68A 3PO3C 4KN7A 3S15C 2CX8A 4XLNA 2WAQD 4OIRA 2PPBA 3K7AC 2JA6C 4Y7NC 4C3JC 4A3EC 3HOXC 1B75A 4A3BC 3RZOC 2HZ7A 1TWGC 5C44C 2KPUA 1WCMC 1D6KA 4WFNS 4OIQA 2NVYC 4WCES 5DM7S 3GTJC 3I4MC 4LK0A 1VHYA 5BNZA 4LLGA 3HOWC 2GAEA 1I50C 4A93C 1Z85A 3HKZD 4E8BA 4BY1C 2R7ZC 1Y1WC 4A3GC 1Y1VC 1NYLA 3GTKC 4UY88 3W2VB 1QRUA 3KW2A 2L5NA 4A3CC 4OIPA 5IP7C 3HOUC 2A69A 2WB1D 4C3HC 2NVXC 2A6EA 1TWFC 4G7ZA 2R92C 5C4JC 5HQHA 2PNWA 3GTQC 4JK1A 4C3IC 2Y0SD 2YU9C 5HL7S 2B63C 3S17C 3GTOC 4LK1A 5TMCA 4LJZA 2KXYA 4G7OA 4A3DC 3WODA 3LYWA 2L3UA 1O0BA 2EGWA 1R9TC 1YNNA 2ZJPS 5JVGS 4GZYA 4P2BA 3EQLA 4XSXA 1K83C 4QIWD 5IYCC 2PI8A 1IW7A 3M4OC 1QRSA 5C4XC 3S1NC 1O0CA 5IP9C 4IO9S 1TWAC 4IOCS 4G7HA 4V194 2E2HC 4A3LC 2VUMC 2RD2A 3H3VD 1EUYA 5C3EC 1DFUP 5GADW 3GTPC 2EGVA 4WFAS 4A3FC 2JA7C 4Q4ZA 2E2JC 1SFOC 4WFBS 5JVHS 2PMZD 3RZDC 3S1QC 4BXXC 4YFKA 4H3SA 3FKIC 4BBSC 1EXDA 3S2HC 4A3JC 5FLMC 4BBRC 4Q5SA 2CW0A 2KQ1A 2Z0YA 4A3IC 5IYDC 3GTGC 2E2IC 1I3QC 5DM6S 1EUQA 1QRTA 1YNJA 1TWHC 4QJVA 4MEYA
chains in the Genus database with same CATH topology
1ZJWA 3AIIA 2ZJPS 1UDXA 5IZNA 5JVGS 3X1LB 4JXZA 4P2BA 5BNZA 4H4KA 4JYZA 5GAHW 1GTSA 3PIOS 1QRSA 4U67S 3W2WB 1O0CA 3CF5S 4IO9S 4IOCS 4WF9S 4V194 1NYLA 2ZJQS 2RD2A 3W2VB 1EUYA 1QRUA 4UY88 1DFUP 5GADW 3PIPS 3J7ZV 4JXXA 4WFAS 1GTRA 1QTQA 1FEUA 2ZJRS 3DLLS 4WFBS 5JVHS 4IOAS 4H3SA 1EXDA 5GAEW 5HL7S 1B75A 2HZ7A 5GAGW 4WFNS 5DM6S 2RE8A 1D6KA 1EUQA 1O0BA 1QRTA 4WCES 5DM7S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZJW A;  3AII A;  2ZJP S;  5JVG S;  5IZN A;  4JXZ A;  4P2B A;  5BNZ A;  4JYZ A;  5GAH W;  1GTS A;  3PIO S;  1QRS A;  4U67 S;  1O0C A;  3CF5 S;  4IO9 S;  4IOC S;  4WF9 S;  1NYL A;  2ZJQ S;  2RD2 A;  1EUY A;  1QRU A;  4UY8 8;  1DFU P;  5GAD W;  3PIP S;  3J7Z V;  4JXX A;  4WFA S;  1GTR A;  1QTQ A;  1FEU A;  2ZJR S;  3DLL S;  4WFB S;  5JVH S;  4IOA S;  4H3S A;  1EXD A;  5GAE W;  5HL7 S;  1B75 A;  2HZ7 A;  5GAG W;  4WFN S;  5DM6 S;  2RE8 A;  1D6K A;  1EUQ A;  1O0B A;  1QRT A;  4WCE S;  5DM7 S; 
#chains in the Genus database with same CATH topology
 1I6H C;  1UDX A;  3CZB A;  4MQ9 A;  3X1L B;  4YFN A;  4ZH4 A;  5IYB C;  4A3M C;  3HOY C;  4JYZ A;  5GAH W;  1GTS A;  3PIO S;  4YG2 A;  2O5I A;  3S2D C;  4U67 S;  3W2W B;  1I6V A;  4OIO A;  4WF9 S;  4J3C A;  3S1R C;  4L69 A;  4AYB D;  2G6G A;  2PA8 D;  4MEX A;  4KN4 A;  4XLP A;  1QTQ A;  2NVQ C;  1BDF A;  1TWC C;  3S1M C;  1VHK A;  3DLL S;  2JA5 C;  4IOA S;  3S16 C;  3GTL C;  1HQM A;  5GAE W;  5D4D A;  3I4N C;  4X6A C;  2PIC A;  2AE0 X;  4BY7 C;  2A6H A;  2PJJ A;  4OIN A;  2JA8 C;  5GAG W;  2RE8 A;  2G5D A;  4A3K C;  4XSZ A;  5TMF A;  1SMY A;  3DXJ A;  1ZJW A;  3AII A;  3H0G C;  3M3Y C;  5IZN A;  4NOI A;  1NXZ A;  4JXZ A;  3HOZ C;  4H4K A;  3S14 C;  2NVT C;  3CQZ C;  4KMU A;  1ZYR A;  2NWA A;  4YFX A;  2R93 C;  3CF5 S;  3HOV C;  2O5J A;  2ZJQ S;  4Y52 C;  1V6Z A;  3PIP S;  2BE5 A;  3J7Z V;  4C2M C;  4JXX A;  3GTM C;  1GTR A;  1FEU A;  3PO2 C;  2ZJR S;  2A68 A;  3PO3 C;  4KN7 A;  3S15 C;  2CX8 A;  4XLN A;  2WAQ D;  4OIR A;  2PPB A;  3K7A C;  2JA6 C;  4Y7N C;  4C3J C;  4A3E C;  3HOX C;  1B75 A;  4A3B C;  3RZO C;  2HZ7 A;  1TWG C;  5C44 C;  2KPU A;  1WCM C;  1D6K A;  4WFN S;  4OIQ A;  2NVY C;  4WCE S;  5DM7 S;  3GTJ C;  3I4M C;  4LK0 A;  1VHY A;  5BNZ A;  4LLG A;  3HOW C;  2GAE A;  1I50 C;  4A93 C;  1Z85 A;  3HKZ D;  4E8B A;  4BY1 C;  2R7Z C;  1Y1W C;  4A3G C;  1Y1V C;  1NYL A;  3GTK C;  4UY8 8;  3W2V B;  1QRU A;  3KW2 A;  2L5N A;  4A3C C;  4OIP A;  5IP7 C;  3HOU C;  2A69 A;  2WB1 D;  4C3H C;  2NVX C;  2A6E A;  1TWF C;  4G7Z A;  2R92 C;  5C4J C;  5HQH A;  2PNW A;  3GTQ C;  4JK1 A;  4C3I C;  2Y0S D;  2YU9 C;  5HL7 S;  2B63 C;  3S17 C;  3GTO C;  4LK1 A;  5TMC A;  4LJZ A;  2KXY A;  4G7O A;  4A3D C;  3WOD A;  3LYW A;  2L3U A;  1O0B A;  2EGW A;  1R9T C;  1YNN A;  2ZJP S;  5JVG S;  4GZY A;  4P2B A;  3EQL A;  4XSX A;  1K83 C;  4QIW D;  5IYC C;  2PI8 A;  1IW7 A;  3M4O C;  1QRS A;  5C4X C;  3S1N C;  1O0C A;  5IP9 C;  4IO9 S;  1TWA C;  4IOC S;  4G7H A;  4V19 4;  2E2H C;  4A3L C;  2VUM C;  2RD2 A;  3H3V D;  1EUY A;  5C3E C;  1DFU P;  5GAD W;  3GTP C;  2EGV A;  4WFA S;  4A3F C;  2JA7 C;  4Q4Z A;  2E2J C;  1SFO C;  4WFB S;  5JVH S;  2PMZ D;  3RZD C;  3S1Q C;  4BXX C;  4YFK A;  4H3S A;  3FKI C;  4BBS C;  1EXD A;  3S2H C;  4A3J C;  5FLM C;  4BBR C;  4Q5S A;  2CW0 A;  2KQ1 A;  2Z0Y A;  4A3I C;  5IYD C;  3GTG C;  2E2I C;  1I3Q C;  5DM6 S;  1EUQ A;  1QRT A;  1YNJ A;  1TWH C;  4QJV A;  4MEY A; 
#chains in the Genus database with same CATH homology
 1ZJW A;  3AII A;  2ZJP S;  1UDX A;  5IZN A;  5JVG S;  3X1L B;  4JXZ A;  4P2B A;  5BNZ A;  4H4K A;  4JYZ A;  5GAH W;  1GTS A;  3PIO S;  1QRS A;  4U67 S;  3W2W B;  1O0C A;  3CF5 S;  4IO9 S;  4IOC S;  4WF9 S;  4V19 4;  1NYL A;  2ZJQ S;  2RD2 A;  3W2V B;  1EUY A;  1QRU A;  4UY8 8;  1DFU P;  5GAD W;  3PIP S;  3J7Z V;  4JXX A;  4WFA S;  1GTR A;  1QTQ A;  1FEU A;  2ZJR S;  3DLL S;  4WFB S;  5JVH S;  4IOA S;  4H3S A;  1EXD A;  5GAE W;  5HL7 S;  1B75 A;  2HZ7 A;  5GAG W;  4WFN S;  5DM6 S;  2RE8 A;  1D6K A;  1EUQ A;  1O0B A;  1QRT A;  4WCE S;  5DM7 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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