5HOLA

The crystal structure of the mers-cov macro domain with adp-ribose
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
167
structure length
167
Chain Sequence
MDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTIV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.
pubmed doi rcsb
source organism Middle east respiratory syndrome coronavirus
molecule tags Viral protein
molecule keywords ORF1a
total genus 54
structure length 167
sequence length 167
ec nomenclature ec 2.7.7.48: RNA-directed RNA polymerase.
pdb deposition date 2016-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 5holA00
1TY8A 1TXZA 2EWBA 5CB5A 1ZR5A 4ABKA 3PEIA 4J5RA 4ABLA 5FSYA 2EEEA 4JCAA 1YD9A 5HOLA 4ZX8A 1LANA 3KQXA 3EJGA 3EKEA 1BLLE 2XD7A 4ESSA 2BFRA 4GUAA 3ETIA 4TU0A 3KQZA 4GVVA 4J4ZA 4K3NA 4D86A 5CB3A 1VHUA 1LCPA 3Q71A 4IQYA 3V2BA 3V45A 1GYTA 3IIFA 4R6TA 2BFQA 1BPNA 2X47A 5FSXA 4ETKA 4ZYQA 3JZTA 1HJZA 4ZY2A 3EWQA 3GPOA 2L8RA 3GPQA 4J5QA 3KR4A 4KSIA 3SIIA 5CBMA 5DUSA 3GPGA 3SIGA 5CMSA 4ZX9A 4KYBA 4R76A 3SIHA 3EW5A 3Q6ZA 3IIDA 4K0CA 5E3BA 1ZR3A 1BPMA 5FSUA 2VRIA 5D8NA 3JRUA 3EWRA 4UMLA 2FXKA 1LAMA 4JLLA 2FAVA 4R7MA 4ETJA 2DX6A 4J5SA 3H8GA 3T8WA 2J9AA 1SPVA 3KZWA 4GVWA 2AFCA 4X2TA 4ZY1A 5FSZA 3EWPA 3VFQA 3KR5A 4JGKA 2ACFA 4JVVA 5FSVA 2LGRA 3H8EA 1NJRA 5HIHA 3IJ3A 3H8FA 4ZI6A 3EJFA 3SIJA 3GQOA 2FG1A 3EWOA 3GQEA 5AILA 4ZY0A 1LAPA
chains in the Genus database with same CATH superfamily
1TY8A 1TXZA 2EWBA 5CB5A 1ZR5A 4ABKA 3PEIA 4J5RA 4ABLA 5FSYA 2EEEA 4JCAA 1YD9A 5HOLA 4ZX8A 1LANA 3KQXA 3EJGA 3EKEA 1BLLE 2XD7A 4ESSA 2BFRA 4GUAA 3ETIA 4TU0A 3KQZA 4GVVA 4J4ZA 4K3NA 4D86A 5CB3A 1VHUA 2JZDA 1LCPA 3Q71A 4IQYA 3V2BA 3V45A 1GYTA 3IIFA 4R6TA 2BFQA 1BPNA 2X47A 5FSXA 4ETKA 4ZYQA 3JZTA 1HJZA 4ZY2A 3EWQA 3GPOA 2L8RA 3GPQA 4J5QA 3KR4A 4KSIA 3SIIA 5CBMA 5DUSA 3GPGA 3SIGA 5CMSA 4ZX9A 4KYBA 4R76A 3SIHA 3EW5A 3Q6ZA 3IIDA 4K0CA 5E3BA 1ZR3A 1BPMA 5FSUA 2VRIA 5D8NA 3JRUA 3EWRA 4UMLA 2FXKA 1LAMA 4JLLA 2FAVA 4R7MA 4ETJA 2DX6A 4J5SA 3H8GA 3T8WA 2J9AA 2RNKA 1SPVA 3KZWA 4GVWA 2AFCA 4X2TA 4ZY1A 5FSZA 3EWPA 3VFQA 3KR5A 4JGKA 2ACFA 4JVVA 5FSVA 2LGRA 3H8EA 1NJRA 5HIHA 3IJ3A 3H8FA 2JZEA 2KQVA 2WCTA 2W2GA 4ZI6A 3EJFA 3SIJA 3GQOA 2JZFA 2FG1A 3EWOA 3GQEA 5AILA 4ZY0A 1LAPA
chains in the Genus database with same CATH topology
1TY8A 1TXZA 2EWBA 5CB5A 1ZR5A 4ABKA 3PEIA 4J5RA 4ABLA 5FSYA 2EEEA 4JCAA 1YD9A 5HOLA 4ZX8A 1LANA 3KQXA 3EJGA 3EKEA 1BLLE 2XD7A 4ESSA 2BFRA 4GUAA 3ETIA 4TU0A 3KQZA 4GVVA 4J4ZA 4K3NA 4D86A 5CB3A 1VHUA 1LCPA 3Q71A 4IQYA 3V2BA 3V45A 1GYTA 3IIFA 4R6TA 2BFQA 1BPNA 2X47A 5FSXA 4ETKA 4ZYQA 3JZTA 1HJZA 4ZY2A 3EWQA 3GPOA 2L8RA 3GPQA 4J5QA 3KR4A 4KSIA 3SIIA 5CBMA 5DUSA 3GPGA 3SIGA 5CMSA 4ZX9A 4KYBA 4R76A 3SIHA 3EW5A 3Q6ZA 3IIDA 4K0CA 5E3BA 1ZR3A 1BPMA 5FSUA 2VRIA 5D8NA 3JRUA 3EWRA 4UMLA 2FXKA 1LAMA 4JLLA 2FAVA 4R7MA 4ETJA 2DX6A 4J5SA 3H8GA 3T8WA 2J9AA 1SPVA 3KZWA 4GVWA 2AFCA 4X2TA 4ZY1A 5FSZA 3EWPA 3VFQA 3KR5A 4JGKA 2ACFA 4JVVA 5FSVA 2LGRA 3H8EA 1NJRA 5HIHA 3IJ3A 3H8FA 4ZI6A 3EJFA 3SIJA 3GQOA 2FG1A 3EWOA 3GQEA 5AILA 4ZY0A 1LAPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TY8 A;  1TXZ A;  2EWB A;  5CB5 A;  1ZR5 A;  4ABK A;  3PEI A;  4J5R A;  4ABL A;  5FSY A;  2EEE A;  4JCA A;  1YD9 A;  5HOL A;  4ZX8 A;  1LAN A;  3KQX A;  3EJG A;  3EKE A;  1BLL E;  2XD7 A;  4ESS A;  2BFR A;  4GUA A;  3ETI A;  4TU0 A;  3KQZ A;  4GVV A;  4J4Z A;  4K3N A;  4D86 A;  5CB3 A;  1VHU A;  1LCP A;  3Q71 A;  4IQY A;  3V2B A;  3V45 A;  1GYT A;  3IIF A;  4R6T A;  2BFQ A;  1BPN A;  2X47 A;  5FSX A;  4ETK A;  4ZYQ A;  3JZT A;  1HJZ A;  4ZY2 A;  3EWQ A;  3GPO A;  2L8R A;  3GPQ A;  4J5Q A;  3KR4 A;  4KSI A;  3SII A;  5CBM A;  5DUS A;  3GPG A;  3SIG A;  5CMS A;  4ZX9 A;  4KYB A;  4R76 A;  3SIH A;  3EW5 A;  3Q6Z A;  3IID A;  4K0C A;  5E3B A;  1ZR3 A;  1BPM A;  5FSU A;  2VRI A;  5D8N A;  3JRU A;  3EWR A;  4UML A;  2FXK A;  1LAM A;  4JLL A;  2FAV A;  4R7M A;  4ETJ A;  2DX6 A;  4J5S A;  3H8G A;  3T8W A;  2J9A A;  1SPV A;  3KZW A;  4GVW A;  2AFC A;  4X2T A;  4ZY1 A;  5FSZ A;  3EWP A;  3VFQ A;  3KR5 A;  4JGK A;  2ACF A;  4JVV A;  5FSV A;  2LGR A;  3H8E A;  1NJR A;  5HIH A;  3IJ3 A;  3H8F A;  4ZI6 A;  3EJF A;  3SIJ A;  3GQO A;  2FG1 A;  3EWO A;  3GQE A;  5AIL A;  4ZY0 A;  1LAP A; 
#chains in the Genus database with same CATH topology
 1TY8 A;  1TXZ A;  2EWB A;  5CB5 A;  1ZR5 A;  4ABK A;  3PEI A;  4J5R A;  4ABL A;  5FSY A;  2EEE A;  4JCA A;  1YD9 A;  5HOL A;  4ZX8 A;  1LAN A;  3KQX A;  3EJG A;  3EKE A;  1BLL E;  2XD7 A;  4ESS A;  2BFR A;  4GUA A;  3ETI A;  4TU0 A;  3KQZ A;  4GVV A;  4J4Z A;  4K3N A;  4D86 A;  5CB3 A;  1VHU A;  2JZD A;  1LCP A;  3Q71 A;  4IQY A;  3V2B A;  3V45 A;  1GYT A;  3IIF A;  4R6T A;  2BFQ A;  1BPN A;  2X47 A;  5FSX A;  4ETK A;  4ZYQ A;  3JZT A;  1HJZ A;  4ZY2 A;  3EWQ A;  3GPO A;  2L8R A;  3GPQ A;  4J5Q A;  3KR4 A;  4KSI A;  3SII A;  5CBM A;  5DUS A;  3GPG A;  3SIG A;  5CMS A;  4ZX9 A;  4KYB A;  4R76 A;  3SIH A;  3EW5 A;  3Q6Z A;  3IID A;  4K0C A;  5E3B A;  1ZR3 A;  1BPM A;  5FSU A;  2VRI A;  5D8N A;  3JRU A;  3EWR A;  4UML A;  2FXK A;  1LAM A;  4JLL A;  2FAV A;  4R7M A;  4ETJ A;  2DX6 A;  4J5S A;  3H8G A;  3T8W A;  2J9A A;  2RNK A;  1SPV A;  3KZW A;  4GVW A;  2AFC A;  4X2T A;  4ZY1 A;  5FSZ A;  3EWP A;  3VFQ A;  3KR5 A;  4JGK A;  2ACF A;  4JVV A;  5FSV A;  2LGR A;  3H8E A;  1NJR A;  5HIH A;  3IJ3 A;  3H8F A;  2JZE A;  2KQV A;  2WCT A;  2W2G A;  4ZI6 A;  3EJF A;  3SIJ A;  3GQO A;  2JZF A;  2FG1 A;  3EWO A;  3GQE A;  5AIL A;  4ZY0 A;  1LAP A; 
#chains in the Genus database with same CATH homology
 1TY8 A;  1TXZ A;  2EWB A;  5CB5 A;  1ZR5 A;  4ABK A;  3PEI A;  4J5R A;  4ABL A;  5FSY A;  2EEE A;  4JCA A;  1YD9 A;  5HOL A;  4ZX8 A;  1LAN A;  3KQX A;  3EJG A;  3EKE A;  1BLL E;  2XD7 A;  4ESS A;  2BFR A;  4GUA A;  3ETI A;  4TU0 A;  3KQZ A;  4GVV A;  4J4Z A;  4K3N A;  4D86 A;  5CB3 A;  1VHU A;  1LCP A;  3Q71 A;  4IQY A;  3V2B A;  3V45 A;  1GYT A;  3IIF A;  4R6T A;  2BFQ A;  1BPN A;  2X47 A;  5FSX A;  4ETK A;  4ZYQ A;  3JZT A;  1HJZ A;  4ZY2 A;  3EWQ A;  3GPO A;  2L8R A;  3GPQ A;  4J5Q A;  3KR4 A;  4KSI A;  3SII A;  5CBM A;  5DUS A;  3GPG A;  3SIG A;  5CMS A;  4ZX9 A;  4KYB A;  4R76 A;  3SIH A;  3EW5 A;  3Q6Z A;  3IID A;  4K0C A;  5E3B A;  1ZR3 A;  1BPM A;  5FSU A;  2VRI A;  5D8N A;  3JRU A;  3EWR A;  4UML A;  2FXK A;  1LAM A;  4JLL A;  2FAV A;  4R7M A;  4ETJ A;  2DX6 A;  4J5S A;  3H8G A;  3T8W A;  2J9A A;  1SPV A;  3KZW A;  4GVW A;  2AFC A;  4X2T A;  4ZY1 A;  5FSZ A;  3EWP A;  3VFQ A;  3KR5 A;  4JGK A;  2ACF A;  4JVV A;  5FSV A;  2LGR A;  3H8E A;  1NJR A;  5HIH A;  3IJ3 A;  3H8F A;  4ZI6 A;  3EJF A;  3SIJ A;  3GQO A;  2FG1 A;  3EWO A;  3GQE A;  5AIL A;  4ZY0 A;  1LAP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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