5HVBA

5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
186
structure length
186
Chain Sequence
VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLVIMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human dihydrofolate reductase ternary complex with a series of fluorine substituted 5-methyl-6-(1-napthylthio)[2,3-d]pyrimidine-2,4-diamines
rcsb
molecule keywords Dihydrofolate reductase
molecule tags Oxidoreductase/oxidoreductase inhibitor
source organism Homo sapiens
total genus 54
structure length 186
sequence length 186
ec nomenclature ec 1.5.1.3: Dihydrofolate reductase.
pdb deposition date 2016-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00186 DHFR_1 Dihydrofolate reductase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.430.10 Alpha Beta 3-Layer(aba) Sandwich Dihydrofolate Reductase, subunit A Dihydrofolate Reductase, subunit A 5hvbA00
1DAJA 3JTWA 4KBNA 3IX9A 5ECCA 4XE6X 1RB3A 1DR4A 3DL6A 4TU5X 3M08A 3FY9X 3SRQX 2HXVA 3JVXA 3TD8A 4DDRA 4XT4A 3JW5A 4P68A 4XT8A 1DYRA 3F0XX 1S3YA 1RF7A 1RD7A 3E0BA 1DHJA 1DR2A 1QZFA 1AOEA 3FQ0A 1LY4A 1DR3A 4HA7A 5HVBA 3JSUA 2W9GA 4HA9A 4Q67A 4QI9A 1RA9A 4XRBA 3FRAX 8DFRA 4HOFA 3QLSA 1DR1A 3JWMA 1PD8A 1VJ3A 3VCOA 3EX8A 2ANQA 4EIZA 4P3QA 3CLBA 4Q6AA 3D80A 4OR7A 3QL3A 3UM5A 3QFXA 2CD2A 3HBBA 1LY3A 3INVA 3NZCX 2W9SA 3SR5X 3QYLA 1RB2A 3IROA 4QLEA 4FHBA 4ELGA 1RH3A 1M78A 2L28A 2W9TA 4IXFX 3GHVA 4X5FA 5U26A 4PSSA 4EJ1A 2AZNA 4PSYA 3F0SX 3SRUX 4LAGX 3SGYA 4QJZD 3NZDA 4CD2A 5HVEA 2BL9A 3FQVA 1CZ3A 3TQBA 1OHJA 1RA2A 3QLXA 3FRBX 4RGCA 3OCHA 1YHOA 2FZJA 4QHVA 3CSEA 3FRFX 4NX7A 1DREA 1S3UA 3IA4A 2KGKA 1RX6A 5CC9A 1KMVA 5JG0X 2ZZAA 1DRHA 3ZPGA 3F91A 3M09A 4DPHA 3QYOA 4KJJA 3QLWA 1DYIA 4OSGA 3TQ9A 1PDBA 1JOMA 4DPDA 2W3WA 1BZFA 1RX3A 3LG4A 3KFYA 2W3AA 4EIGA 3NZAX 1IA3A 4IXED 4I13A 5HI6A 4LAHX 1DR6A 3DAUA 3TQ8A 3GI2A 1BOZA 3R33A 3EELA 4EILA 1RA3A 4KAKA 3CD2A 5HT5A 1U71A 4LEKX 1DG7A 1M79A 3IA5A 2BLBA 4FGHA 2INQA 4X5IA 4H97A 3UM6A 4KM0A 3L3RA 2LF1A 5HF2X 3DGAA 4M2XA 3GHWA 3SRWX 4M6JA 5HQZA 3F0BX 2HM9A 3RO9A 3K45A 3UM8A 1DDSA 1KLKA 1TDRA 3F8YA 6DFRA 1RX8A 3FL8A 2C2SA 3SAIA 2JYBA 1DYHA 1DHIA 3ZPCA 3DATA 4DFRA 3IRNA 3ROAA 4KJKA 3NTZA 1U72A 3NU0A 4PTJA 1RE7A 4PTHA 1DR7A 5JA3A 3FREX 3QG2A 4ECKA 4G8ZX 3DL5A 3OAFA 2QK8A 2OBCA 3SRRX 4HOGA 2BLAA 1DF7A 1JUVA 2P4GA 3TQAA 1OHKA 5E8QA 3NZBX 3RG9A 4M6KA 4M7VA 5CCCA 3S7AA 4KY8A 4KY4A 1DG8A 2OIPA 1RA1A 1DRFA 1DLRA 1HFRA 3NXXA 5ECXA 3KJRA 3K47A 4X5JA 1JOLA 4ELHA 4QLFA 1E26A 4KYAA 4IXGX 3N0HA 3HJ3A 3F0UX 2DHFA 5DXVA 1RX9A 4KD7A 3QLZA 3NXRA 1DLSA 3GYFA 3KJSA 4PSTA 1KMSA 5HSUA 4KFJA 1J3JA 3D84X 3FYVX 2G6VA 2W3BA 3SA1A 3FYWX 4GH8A 1RX1A 2ITHA 5HF0X 2D0KA 4XT5A 1RX4A 2GD9A 1RX2A 4H95A 3SA2A 4KL9A 1S3WA 2XW7A 4NX6A 1RG7A 4ELEA 3SH2A 1RC4A 4HOEA 3S3VA 2BLCA 3I8AX 4ELFA 4M6LA 1D1GA 3F0QX 4PDJA 1DRAA 1AI9A 1J3KA 5HSRA 3EIGA 1S3VA 2FZHA 5HQYA 3FQCA 3JWFA 4H98A 1MVTA 2C2TA 4Q0DA 4KNEA 4KM2A 3EEMA 1IA4A 1DISA 4KLXA 3NXTA 3K74A 2FZIA 4FGGA 5HT4A 3QLYA 5EAJA 2O7PA 3CL9A 1DRBA 2W9HA 2DRCA 3NXOA 3QL0A 2ANOA 1IA2A 5U27A 4XT6A 5HPBA 1J3IA 1SEJA 1RA8A 4X5GA 3JW3A 4ELBA 1VDRA 1DDRA 3F0VX 3EEJA 4X5HA 1PD9A 7DFRA 2H2QA 1DYJA 2D5NA 1RX5A 4G95A 2HQPA 3NXVA 2W3VA 3FQFA 3JWCA 3DFRA 2B3ZA 1DHFA 4M7UA 3SRSX 3EEKA 1ZDRA 1IA1A 1DR5A 3FQZA 3I3RA 1HFPA 4QJCA 3K2HA 3QGTA 2W3MA 4LAEX 1LUDA 3DG8A 4P3RA 4P66A 4QLGA 3FY8X 3QLRA 3FQOA 3JWKA 3KGYA 4XT7A 1DIUA 3NZ6X 3NXYA 3Q1HA 4XECX 3IRMA 3DRCA 1DG5A 4G3MA 1MVSA 3FRDX 3FS6A 2CIGA 1U70A 3KY8A 3NRRA 5DFRA 1RX7A 4I1NA 3SQYX 1CD2A 1HFQA 4DP3A 3GHCA 5FDAA 3F8ZA 3NZ9X 4KJLA 1AO8A 4KEBA 3FL9A 1M7AA 3S9UA 4H96A 4Q0EA 5HUIA
chains in the Genus database with same CATH superfamily
1DAJA 3JTWA 4KBNA 3IX9A 5ECCA 4XE6X 1RB3A 1DR4A 3DL6A 4TU5X 3M08A 3FY9X 3SRQX 2HXVA 3JVXA 3TD8A 4DDRA 4XT4A 3JW5A 4P68A 4XT8A 1DYRA 3F0XX 1S3YA 1RF7A 1RD7A 3E0BA 1DHJA 1DR2A 1QZFA 1AOEA 3FQ0A 1LY4A 1DR3A 4HA7A 5HVBA 3JSUA 2W9GA 4HA9A 4Q67A 4QI9A 1RA9A 4XRBA 3FRAX 8DFRA 4HOFA 3QLSA 1DR1A 3JWMA 1PD8A 1VJ3A 3VCOA 3EX8A 2ANQA 4EIZA 4P3QA 3CLBA 4Q6AA 3D80A 4OR7A 3QL3A 3UM5A 3QFXA 2CD2A 3HBBA 1LY3A 3INVA 3NZCX 2W9SA 3SR5X 3QYLA 1RB2A 3IROA 4QLEA 4FHBA 4ELGA 1RH3A 1M78A 2L28A 2W9TA 4IXFX 3GHVA 4X5FA 5U26A 4PSSA 4EJ1A 2AZNA 4PSYA 3F0SX 3SRUX 4LAGX 3SGYA 4QJZD 3NZDA 4CD2A 5HVEA 2BL9A 3FQVA 1CZ3A 3TQBA 1OHJA 1RA2A 3QLXA 3FRBX 4RGCA 3OCHA 1YHOA 2FZJA 4QHVA 3CSEA 3FRFX 4NX7A 1DREA 1S3UA 3IA4A 2KGKA 1RX6A 5CC9A 1KMVA 5JG0X 2ZZAA 1DRHA 3ZPGA 3F91A 3M09A 4DPHA 3QYOA 4KJJA 3QLWA 1DYIA 4OSGA 3TQ9A 1PDBA 1JOMA 4DPDA 2W3WA 1BZFA 1RX3A 3LG4A 3KFYA 2W3AA 4EIGA 3NZAX 1IA3A 4IXED 4I13A 5HI6A 4LAHX 1DR6A 3DAUA 3TQ8A 3GI2A 1BOZA 3R33A 3EELA 4EILA 1RA3A 4KAKA 3CD2A 5HT5A 1U71A 4LEKX 1DG7A 1M79A 3IA5A 2BLBA 4FGHA 2INQA 4X5IA 4H97A 3UM6A 4KM0A 3L3RA 2LF1A 5HF2X 3DGAA 4M2XA 3GHWA 3SRWX 4M6JA 5HQZA 3F0BX 2HM9A 3RO9A 3K45A 3UM8A 1DDSA 1KLKA 1TDRA 3F8YA 6DFRA 1RX8A 3FL8A 2C2SA 3SAIA 2JYBA 1DYHA 1DHIA 3ZPCA 3DATA 4DFRA 3IRNA 3ROAA 4KJKA 3NTZA 1U72A 3NU0A 4PTJA 1RE7A 4PTHA 1DR7A 5JA3A 3FREX 3QG2A 4ECKA 4G8ZX 3DL5A 3OAFA 2QK8A 2OBCA 3SRRX 4HOGA 2BLAA 1DF7A 1JUVA 2P4GA 3TQAA 1OHKA 5E8QA 3NZBX 3RG9A 4M6KA 4M7VA 5CCCA 3S7AA 4KY8A 4KY4A 1DG8A 2OIPA 1RA1A 1DRFA 1DLRA 1HFRA 3NXXA 5ECXA 3KJRA 3K47A 4X5JA 1JOLA 4ELHA 4QLFA 1E26A 4KYAA 4IXGX 3N0HA 3HJ3A 3F0UX 2DHFA 5DXVA 1RX9A 4KD7A 3QLZA 3NXRA 1DLSA 3GYFA 3KJSA 4PSTA 1KMSA 5HSUA 4KFJA 1J3JA 3D84X 3FYVX 2G6VA 2W3BA 3SA1A 3FYWX 4GH8A 1RX1A 2ITHA 5HF0X 2D0KA 4XT5A 1RX4A 2GD9A 1RX2A 4H95A 3SA2A 4KL9A 1S3WA 2XW7A 4NX6A 1RG7A 4ELEA 3SH2A 1RC4A 4HOEA 3S3VA 2BLCA 3I8AX 4ELFA 4M6LA 1D1GA 3F0QX 4PDJA 1DRAA 1AI9A 1J3KA 5HSRA 3EIGA 1S3VA 2FZHA 5HQYA 3FQCA 3JWFA 4H98A 1MVTA 2C2TA 4Q0DA 4KNEA 4KM2A 3EEMA 1IA4A 1DISA 4KLXA 3NXTA 3K74A 2FZIA 4FGGA 5HT4A 3QLYA 5EAJA 2O7PA 3CL9A 1DRBA 2W9HA 2DRCA 3NXOA 3QL0A 2ANOA 1IA2A 5U27A 4XT6A 5HPBA 1J3IA 1SEJA 1RA8A 4X5GA 3JW3A 4ELBA 1VDRA 1DDRA 3F0VX 3EEJA 4X5HA 1PD9A 7DFRA 2H2QA 1DYJA 2D5NA 1RX5A 4G95A 2HQPA 3NXVA 2W3VA 3FQFA 3JWCA 3DFRA 2B3ZA 1DHFA 4M7UA 3SRSX 3EEKA 1ZDRA 1IA1A 1DR5A 3FQZA 3I3RA 1HFPA 4QJCA 3K2HA 3QGTA 2W3MA 4LAEX 1LUDA 3DG8A 4P3RA 4P66A 4QLGA 3FY8X 3QLRA 3FQOA 3JWKA 3KGYA 4XT7A 1DIUA 3NZ6X 3NXYA 3Q1HA 4XECX 3IRMA 3DRCA 1DG5A 4G3MA 1MVSA 3FRDX 3FS6A 2CIGA 1U70A 3KY8A 3NRRA 5DFRA 1RX7A 4I1NA 3SQYX 1CD2A 1HFQA 4DP3A 3GHCA 5FDAA 3F8ZA 3NZ9X 4KJLA 1AO8A 4KEBA 3FL9A 1M7AA 3S9UA 4H96A 4Q0EA 5HUIA
chains in the Genus database with same CATH topology
1DAJA 3JTWA 4KBNA 3IX9A 5ECCA 4XE6X 1RB3A 1DR4A 3DL6A 4TU5X 3M08A 3FY9X 3SRQX 2HXVA 3JVXA 3TD8A 4DDRA 4XT4A 3JW5A 4P68A 4XT8A 1DYRA 3F0XX 1S3YA 1RF7A 1RD7A 3E0BA 1DHJA 1DR2A 1QZFA 1AOEA 3FQ0A 1LY4A 1DR3A 4HA7A 5HVBA 3JSUA 2W9GA 4HA9A 4Q67A 4QI9A 1RA9A 4XRBA 3FRAX 8DFRA 4HOFA 3QLSA 1DR1A 3JWMA 1PD8A 1VJ3A 3VCOA 3EX8A 2ANQA 4EIZA 4P3QA 3CLBA 4Q6AA 3D80A 4OR7A 3QL3A 3UM5A 3QFXA 2CD2A 3HBBA 1LY3A 3INVA 3NZCX 2W9SA 3SR5X 3QYLA 1RB2A 3IROA 4QLEA 4FHBA 4ELGA 1RH3A 1M78A 2L28A 2W9TA 4IXFX 3GHVA 4X5FA 5U26A 4PSSA 4EJ1A 2AZNA 4PSYA 3F0SX 3SRUX 4LAGX 3SGYA 4QJZD 3NZDA 4CD2A 5HVEA 2BL9A 3FQVA 1CZ3A 3TQBA 1OHJA 1RA2A 3QLXA 3FRBX 4RGCA 3OCHA 1YHOA 2FZJA 4QHVA 3CSEA 3FRFX 4NX7A 1DREA 1S3UA 3IA4A 2KGKA 1RX6A 5CC9A 1KMVA 5JG0X 2ZZAA 1DRHA 3ZPGA 3F91A 3M09A 4DPHA 3QYOA 4KJJA 3QLWA 1DYIA 4OSGA 3TQ9A 1PDBA 1JOMA 4DPDA 2W3WA 1BZFA 1RX3A 3LG4A 3KFYA 2W3AA 4EIGA 3NZAX 1IA3A 4IXED 4I13A 5HI6A 4LAHX 1DR6A 3DAUA 3TQ8A 3GI2A 1BOZA 3R33A 3EELA 4EILA 1RA3A 4KAKA 3CD2A 5HT5A 1U71A 4LEKX 1DG7A 1M79A 3IA5A 2BLBA 4FGHA 2INQA 4X5IA 4H97A 3UM6A 4KM0A 3L3RA 2LF1A 5HF2X 3DGAA 4M2XA 3GHWA 3SRWX 4M6JA 5HQZA 3F0BX 2HM9A 3RO9A 3K45A 3UM8A 1DDSA 1KLKA 1TDRA 3F8YA 6DFRA 1RX8A 3FL8A 2C2SA 3SAIA 2JYBA 1DYHA 1DHIA 3ZPCA 3DATA 4DFRA 3IRNA 3ROAA 4KJKA 3NTZA 1U72A 3NU0A 4PTJA 1RE7A 4PTHA 1DR7A 5JA3A 3FREX 3QG2A 4ECKA 4G8ZX 3DL5A 3OAFA 2QK8A 2OBCA 3SRRX 4HOGA 2BLAA 1DF7A 1JUVA 2P4GA 3TQAA 1OHKA 5E8QA 3NZBX 3RG9A 4M6KA 4M7VA 5CCCA 3S7AA 4KY8A 4KY4A 1DG8A 2OIPA 1RA1A 1DRFA 1DLRA 1HFRA 3NXXA 5ECXA 3KJRA 3K47A 4X5JA 1JOLA 4ELHA 4QLFA 1E26A 4KYAA 4IXGX 3N0HA 3HJ3A 3F0UX 2DHFA 5DXVA 1RX9A 4KD7A 3QLZA 3NXRA 1DLSA 3GYFA 3KJSA 4PSTA 1KMSA 5HSUA 4KFJA 1J3JA 3D84X 3FYVX 2G6VA 2W3BA 3SA1A 3FYWX 4GH8A 1RX1A 2ITHA 5HF0X 2D0KA 4XT5A 1RX4A 2GD9A 1RX2A 4H95A 3SA2A 4KL9A 1S3WA 2XW7A 4NX6A 1RG7A 4ELEA 3SH2A 1RC4A 4HOEA 3S3VA 2BLCA 3I8AX 4ELFA 4M6LA 1D1GA 3F0QX 4PDJA 1DRAA 1AI9A 1J3KA 5HSRA 3EIGA 1S3VA 2FZHA 5HQYA 3FQCA 3JWFA 4H98A 1MVTA 2C2TA 4Q0DA 4KNEA 4KM2A 3EEMA 1IA4A 1DISA 4KLXA 3NXTA 3K74A 2FZIA 4FGGA 5HT4A 3QLYA 5EAJA 2O7PA 3CL9A 1DRBA 2W9HA 2DRCA 3NXOA 3QL0A 2ANOA 1IA2A 5U27A 4XT6A 5HPBA 1J3IA 1SEJA 1RA8A 4X5GA 3JW3A 4ELBA 1VDRA 1DDRA 3F0VX 3EEJA 4X5HA 1PD9A 7DFRA 2H2QA 1DYJA 2D5NA 1RX5A 4G95A 2HQPA 3NXVA 2W3VA 3FQFA 3JWCA 3DFRA 2B3ZA 1DHFA 4M7UA 3SRSX 3EEKA 1ZDRA 1IA1A 1DR5A 3FQZA 3I3RA 1HFPA 4QJCA 3K2HA 3QGTA 2W3MA 4LAEX 1LUDA 3DG8A 4P3RA 4P66A 4QLGA 3FY8X 3QLRA 3FQOA 3JWKA 3KGYA 4XT7A 1DIUA 3NZ6X 3NXYA 3Q1HA 4XECX 3IRMA 3DRCA 1DG5A 4G3MA 1MVSA 3FRDX 3FS6A 2CIGA 1U70A 3KY8A 3NRRA 5DFRA 1RX7A 4I1NA 3SQYX 1CD2A 1HFQA 4DP3A 3GHCA 5FDAA 3F8ZA 3NZ9X 4KJLA 1AO8A 4KEBA 3FL9A 1M7AA 3S9UA 4H96A 4Q0EA 5HUIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DAJ A;  3JTW A;  4KBN A;  3IX9 A;  5ECC A;  4XE6 X;  1RB3 A;  1DR4 A;  3DL6 A;  4TU5 X;  3M08 A;  3FY9 X;  3SRQ X;  2HXV A;  3JVX A;  3TD8 A;  4DDR A;  4XT4 A;  3JW5 A;  4P68 A;  4XT8 A;  1DYR A;  3F0X X;  1S3Y A;  1RF7 A;  1RD7 A;  3E0B A;  1DHJ A;  1DR2 A;  1QZF A;  1AOE A;  3FQ0 A;  1LY4 A;  1DR3 A;  4HA7 A;  5HVB A;  3JSU A;  2W9G A;  4HA9 A;  4Q67 A;  4QI9 A;  1RA9 A;  4XRB A;  3FRA X;  8DFR A;  4HOF A;  3QLS A;  1DR1 A;  3JWM A;  1PD8 A;  1VJ3 A;  3VCO A;  3EX8 A;  2ANQ A;  4EIZ A;  4P3Q A;  3CLB A;  4Q6A A;  3D80 A;  4OR7 A;  3QL3 A;  3UM5 A;  3QFX A;  2CD2 A;  3HBB A;  1LY3 A;  3INV A;  3NZC X;  2W9S A;  3SR5 X;  3QYL A;  1RB2 A;  3IRO A;  4QLE A;  4FHB A;  4ELG A;  1RH3 A;  1M78 A;  2L28 A;  2W9T A;  4IXF X;  3GHV A;  4X5F A;  5U26 A;  4PSS A;  4EJ1 A;  2AZN A;  4PSY A;  3F0S X;  3SRU X;  4LAG X;  3SGY A;  4QJZ D;  3NZD A;  4CD2 A;  5HVE A;  2BL9 A;  3FQV A;  1CZ3 A;  3TQB A;  1OHJ A;  1RA2 A;  3QLX A;  3FRB X;  4RGC A;  3OCH A;  1YHO A;  2FZJ A;  4QHV A;  3CSE A;  3FRF X;  4NX7 A;  1DRE A;  1S3U A;  3IA4 A;  2KGK A;  1RX6 A;  5CC9 A;  1KMV A;  5JG0 X;  2ZZA A;  1DRH A;  3ZPG A;  3F91 A;  3M09 A;  4DPH A;  3QYO A;  4KJJ A;  3QLW A;  1DYI A;  4OSG A;  3TQ9 A;  1PDB A;  1JOM A;  4DPD A;  2W3W A;  1BZF A;  1RX3 A;  3LG4 A;  3KFY A;  2W3A A;  4EIG A;  3NZA X;  1IA3 A;  4IXE D;  4I13 A;  5HI6 A;  4LAH X;  1DR6 A;  3DAU A;  3TQ8 A;  3GI2 A;  1BOZ A;  3R33 A;  3EEL A;  4EIL A;  1RA3 A;  4KAK A;  3CD2 A;  5HT5 A;  1U71 A;  4LEK X;  1DG7 A;  1M79 A;  3IA5 A;  2BLB A;  4FGH A;  2INQ A;  4X5I A;  4H97 A;  3UM6 A;  4KM0 A;  3L3R A;  2LF1 A;  5HF2 X;  3DGA A;  4M2X A;  3GHW A;  3SRW X;  4M6J A;  5HQZ A;  3F0B X;  2HM9 A;  3RO9 A;  3K45 A;  3UM8 A;  1DDS A;  1KLK A;  1TDR A;  3F8Y A;  6DFR A;  1RX8 A;  3FL8 A;  2C2S A;  3SAI A;  2JYB A;  1DYH A;  1DHI A;  3ZPC A;  3DAT A;  4DFR A;  3IRN A;  3ROA A;  4KJK A;  3NTZ A;  1U72 A;  3NU0 A;  4PTJ A;  1RE7 A;  4PTH A;  1DR7 A;  5JA3 A;  3FRE X;  3QG2 A;  4ECK A;  4G8Z X;  3DL5 A;  3OAF A;  2QK8 A;  2OBC A;  3SRR X;  4HOG A;  2BLA A;  1DF7 A;  1JUV A;  2P4G A;  3TQA A;  1OHK A;  5E8Q A;  3NZB X;  3RG9 A;  4M6K A;  4M7V A;  5CCC A;  3S7A A;  4KY8 A;  4KY4 A;  1DG8 A;  2OIP A;  1RA1 A;  1DRF A;  1DLR A;  1HFR A;  3NXX A;  5ECX A;  3KJR A;  3K47 A;  4X5J A;  1JOL A;  4ELH A;  4QLF A;  1E26 A;  4KYA A;  4IXG X;  3N0H A;  3HJ3 A;  3F0U X;  2DHF A;  5DXV A;  1RX9 A;  4KD7 A;  3QLZ A;  3NXR A;  1DLS A;  3GYF A;  3KJS A;  4PST A;  1KMS A;  5HSU A;  4KFJ A;  1J3J A;  3D84 X;  3FYV X;  2G6V A;  2W3B A;  3SA1 A;  3FYW X;  4GH8 A;  1RX1 A;  2ITH A;  5HF0 X;  2D0K A;  4XT5 A;  1RX4 A;  2GD9 A;  1RX2 A;  4H95 A;  3SA2 A;  4KL9 A;  1S3W A;  2XW7 A;  4NX6 A;  1RG7 A;  4ELE A;  3SH2 A;  1RC4 A;  4HOE A;  3S3V A;  2BLC A;  3I8A X;  4ELF A;  4M6L A;  1D1G A;  3F0Q X;  4PDJ A;  1DRA A;  1AI9 A;  1J3K A;  5HSR A;  3EIG A;  1S3V A;  2FZH A;  5HQY A;  3FQC A;  3JWF A;  4H98 A;  1MVT A;  2C2T A;  4Q0D A;  4KNE A;  4KM2 A;  3EEM A;  1IA4 A;  1DIS A;  4KLX A;  3NXT A;  3K74 A;  2FZI A;  4FGG A;  5HT4 A;  3QLY A;  5EAJ A;  2O7P A;  3CL9 A;  1DRB A;  2W9H A;  2DRC A;  3NXO A;  3QL0 A;  2ANO A;  1IA2 A;  5U27 A;  4XT6 A;  5HPB A;  1J3I A;  1SEJ A;  1RA8 A;  4X5G A;  3JW3 A;  4ELB A;  1VDR A;  1DDR A;  3F0V X;  3EEJ A;  4X5H A;  1PD9 A;  7DFR A;  2H2Q A;  1DYJ A;  2D5N A;  1RX5 A;  4G95 A;  2HQP A;  3NXV A;  2W3V A;  3FQF A;  3JWC A;  3DFR A;  2B3Z A;  1DHF A;  4M7U A;  3SRS X;  3EEK A;  1ZDR A;  1IA1 A;  1DR5 A;  3FQZ A;  3I3R A;  1HFP A;  4QJC A;  3K2H A;  3QGT A;  2W3M A;  4LAE X;  1LUD A;  3DG8 A;  4P3R A;  4P66 A;  4QLG A;  3FY8 X;  3QLR A;  3FQO A;  3JWK A;  3KGY A;  4XT7 A;  1DIU A;  3NZ6 X;  3NXY A;  3Q1H A;  4XEC X;  3IRM A;  3DRC A;  1DG5 A;  4G3M A;  1MVS A;  3FRD X;  3FS6 A;  2CIG A;  1U70 A;  3KY8 A;  3NRR A;  5DFR A;  1RX7 A;  4I1N A;  3SQY X;  1CD2 A;  1HFQ A;  4DP3 A;  3GHC A;  5FDA A;  3F8Z A;  3NZ9 X;  4KJL A;  1AO8 A;  4KEB A;  3FL9 A;  1M7A A;  3S9U A;  4H96 A;  4Q0E A;  5HUI A; 
#chains in the Genus database with same CATH topology
 1DAJ A;  3JTW A;  4KBN A;  3IX9 A;  5ECC A;  4XE6 X;  1RB3 A;  1DR4 A;  3DL6 A;  4TU5 X;  3M08 A;  3FY9 X;  3SRQ X;  2HXV A;  3JVX A;  3TD8 A;  4DDR A;  4XT4 A;  3JW5 A;  4P68 A;  4XT8 A;  1DYR A;  3F0X X;  1S3Y A;  1RF7 A;  1RD7 A;  3E0B A;  1DHJ A;  1DR2 A;  1QZF A;  1AOE A;  3FQ0 A;  1LY4 A;  1DR3 A;  4HA7 A;  5HVB A;  3JSU A;  2W9G A;  4HA9 A;  4Q67 A;  4QI9 A;  1RA9 A;  4XRB A;  3FRA X;  8DFR A;  4HOF A;  3QLS A;  1DR1 A;  3JWM A;  1PD8 A;  1VJ3 A;  3VCO A;  3EX8 A;  2ANQ A;  4EIZ A;  4P3Q A;  3CLB A;  4Q6A A;  3D80 A;  4OR7 A;  3QL3 A;  3UM5 A;  3QFX A;  2CD2 A;  3HBB A;  1LY3 A;  3INV A;  3NZC X;  2W9S A;  3SR5 X;  3QYL A;  1RB2 A;  3IRO A;  4QLE A;  4FHB A;  4ELG A;  1RH3 A;  1M78 A;  2L28 A;  2W9T A;  4IXF X;  3GHV A;  4X5F A;  5U26 A;  4PSS A;  4EJ1 A;  2AZN A;  4PSY A;  3F0S X;  3SRU X;  4LAG X;  3SGY A;  4QJZ D;  3NZD A;  4CD2 A;  5HVE A;  2BL9 A;  3FQV A;  1CZ3 A;  3TQB A;  1OHJ A;  1RA2 A;  3QLX A;  3FRB X;  4RGC A;  3OCH A;  1YHO A;  2FZJ A;  4QHV A;  3CSE A;  3FRF X;  4NX7 A;  1DRE A;  1S3U A;  3IA4 A;  2KGK A;  1RX6 A;  5CC9 A;  1KMV A;  5JG0 X;  2ZZA A;  1DRH A;  3ZPG A;  3F91 A;  3M09 A;  4DPH A;  3QYO A;  4KJJ A;  3QLW A;  1DYI A;  4OSG A;  3TQ9 A;  1PDB A;  1JOM A;  4DPD A;  2W3W A;  1BZF A;  1RX3 A;  3LG4 A;  3KFY A;  2W3A A;  4EIG A;  3NZA X;  1IA3 A;  4IXE D;  4I13 A;  5HI6 A;  4LAH X;  1DR6 A;  3DAU A;  3TQ8 A;  3GI2 A;  1BOZ A;  3R33 A;  3EEL A;  4EIL A;  1RA3 A;  4KAK A;  3CD2 A;  5HT5 A;  1U71 A;  4LEK X;  1DG7 A;  1M79 A;  3IA5 A;  2BLB A;  4FGH A;  2INQ A;  4X5I A;  4H97 A;  3UM6 A;  4KM0 A;  3L3R A;  2LF1 A;  5HF2 X;  3DGA A;  4M2X A;  3GHW A;  3SRW X;  4M6J A;  5HQZ A;  3F0B X;  2HM9 A;  3RO9 A;  3K45 A;  3UM8 A;  1DDS A;  1KLK A;  1TDR A;  3F8Y A;  6DFR A;  1RX8 A;  3FL8 A;  2C2S A;  3SAI A;  2JYB A;  1DYH A;  1DHI A;  3ZPC A;  3DAT A;  4DFR A;  3IRN A;  3ROA A;  4KJK A;  3NTZ A;  1U72 A;  3NU0 A;  4PTJ A;  1RE7 A;  4PTH A;  1DR7 A;  5JA3 A;  3FRE X;  3QG2 A;  4ECK A;  4G8Z X;  3DL5 A;  3OAF A;  2QK8 A;  2OBC A;  3SRR X;  4HOG A;  2BLA A;  1DF7 A;  1JUV A;  2P4G A;  3TQA A;  1OHK A;  5E8Q A;  3NZB X;  3RG9 A;  4M6K A;  4M7V A;  5CCC A;  3S7A A;  4KY8 A;  4KY4 A;  1DG8 A;  2OIP A;  1RA1 A;  1DRF A;  1DLR A;  1HFR A;  3NXX A;  5ECX A;  3KJR A;  3K47 A;  4X5J A;  1JOL A;  4ELH A;  4QLF A;  1E26 A;  4KYA A;  4IXG X;  3N0H A;  3HJ3 A;  3F0U X;  2DHF A;  5DXV A;  1RX9 A;  4KD7 A;  3QLZ A;  3NXR A;  1DLS A;  3GYF A;  3KJS A;  4PST A;  1KMS A;  5HSU A;  4KFJ A;  1J3J A;  3D84 X;  3FYV X;  2G6V A;  2W3B A;  3SA1 A;  3FYW X;  4GH8 A;  1RX1 A;  2ITH A;  5HF0 X;  2D0K A;  4XT5 A;  1RX4 A;  2GD9 A;  1RX2 A;  4H95 A;  3SA2 A;  4KL9 A;  1S3W A;  2XW7 A;  4NX6 A;  1RG7 A;  4ELE A;  3SH2 A;  1RC4 A;  4HOE A;  3S3V A;  2BLC A;  3I8A X;  4ELF A;  4M6L A;  1D1G A;  3F0Q X;  4PDJ A;  1DRA A;  1AI9 A;  1J3K A;  5HSR A;  3EIG A;  1S3V A;  2FZH A;  5HQY A;  3FQC A;  3JWF A;  4H98 A;  1MVT A;  2C2T A;  4Q0D A;  4KNE A;  4KM2 A;  3EEM A;  1IA4 A;  1DIS A;  4KLX A;  3NXT A;  3K74 A;  2FZI A;  4FGG A;  5HT4 A;  3QLY A;  5EAJ A;  2O7P A;  3CL9 A;  1DRB A;  2W9H A;  2DRC A;  3NXO A;  3QL0 A;  2ANO A;  1IA2 A;  5U27 A;  4XT6 A;  5HPB A;  1J3I A;  1SEJ A;  1RA8 A;  4X5G A;  3JW3 A;  4ELB A;  1VDR A;  1DDR A;  3F0V X;  3EEJ A;  4X5H A;  1PD9 A;  7DFR A;  2H2Q A;  1DYJ A;  2D5N A;  1RX5 A;  4G95 A;  2HQP A;  3NXV A;  2W3V A;  3FQF A;  3JWC A;  3DFR A;  2B3Z A;  1DHF A;  4M7U A;  3SRS X;  3EEK A;  1ZDR A;  1IA1 A;  1DR5 A;  3FQZ A;  3I3R A;  1HFP A;  4QJC A;  3K2H A;  3QGT A;  2W3M A;  4LAE X;  1LUD A;  3DG8 A;  4P3R A;  4P66 A;  4QLG A;  3FY8 X;  3QLR A;  3FQO A;  3JWK A;  3KGY A;  4XT7 A;  1DIU A;  3NZ6 X;  3NXY A;  3Q1H A;  4XEC X;  3IRM A;  3DRC A;  1DG5 A;  4G3M A;  1MVS A;  3FRD X;  3FS6 A;  2CIG A;  1U70 A;  3KY8 A;  3NRR A;  5DFR A;  1RX7 A;  4I1N A;  3SQY X;  1CD2 A;  1HFQ A;  4DP3 A;  3GHC A;  5FDA A;  3F8Z A;  3NZ9 X;  4KJL A;  1AO8 A;  4KEB A;  3FL9 A;  1M7A A;  3S9U A;  4H96 A;  4Q0E A;  5HUI A; 
#chains in the Genus database with same CATH homology
 1DAJ A;  3JTW A;  4KBN A;  3IX9 A;  5ECC A;  4XE6 X;  1RB3 A;  1DR4 A;  3DL6 A;  4TU5 X;  3M08 A;  3FY9 X;  3SRQ X;  2HXV A;  3JVX A;  3TD8 A;  4DDR A;  4XT4 A;  3JW5 A;  4P68 A;  4XT8 A;  1DYR A;  3F0X X;  1S3Y A;  1RF7 A;  1RD7 A;  3E0B A;  1DHJ A;  1DR2 A;  1QZF A;  1AOE A;  3FQ0 A;  1LY4 A;  1DR3 A;  4HA7 A;  5HVB A;  3JSU A;  2W9G A;  4HA9 A;  4Q67 A;  4QI9 A;  1RA9 A;  4XRB A;  3FRA X;  8DFR A;  4HOF A;  3QLS A;  1DR1 A;  3JWM A;  1PD8 A;  1VJ3 A;  3VCO A;  3EX8 A;  2ANQ A;  4EIZ A;  4P3Q A;  3CLB A;  4Q6A A;  3D80 A;  4OR7 A;  3QL3 A;  3UM5 A;  3QFX A;  2CD2 A;  3HBB A;  1LY3 A;  3INV A;  3NZC X;  2W9S A;  3SR5 X;  3QYL A;  1RB2 A;  3IRO A;  4QLE A;  4FHB A;  4ELG A;  1RH3 A;  1M78 A;  2L28 A;  2W9T A;  4IXF X;  3GHV A;  4X5F A;  5U26 A;  4PSS A;  4EJ1 A;  2AZN A;  4PSY A;  3F0S X;  3SRU X;  4LAG X;  3SGY A;  4QJZ D;  3NZD A;  4CD2 A;  5HVE A;  2BL9 A;  3FQV A;  1CZ3 A;  3TQB A;  1OHJ A;  1RA2 A;  3QLX A;  3FRB X;  4RGC A;  3OCH A;  1YHO A;  2FZJ A;  4QHV A;  3CSE A;  3FRF X;  4NX7 A;  1DRE A;  1S3U A;  3IA4 A;  2KGK A;  1RX6 A;  5CC9 A;  1KMV A;  5JG0 X;  2ZZA A;  1DRH A;  3ZPG A;  3F91 A;  3M09 A;  4DPH A;  3QYO A;  4KJJ A;  3QLW A;  1DYI A;  4OSG A;  3TQ9 A;  1PDB A;  1JOM A;  4DPD A;  2W3W A;  1BZF A;  1RX3 A;  3LG4 A;  3KFY A;  2W3A A;  4EIG A;  3NZA X;  1IA3 A;  4IXE D;  4I13 A;  5HI6 A;  4LAH X;  1DR6 A;  3DAU A;  3TQ8 A;  3GI2 A;  1BOZ A;  3R33 A;  3EEL A;  4EIL A;  1RA3 A;  4KAK A;  3CD2 A;  5HT5 A;  1U71 A;  4LEK X;  1DG7 A;  1M79 A;  3IA5 A;  2BLB A;  4FGH A;  2INQ A;  4X5I A;  4H97 A;  3UM6 A;  4KM0 A;  3L3R A;  2LF1 A;  5HF2 X;  3DGA A;  4M2X A;  3GHW A;  3SRW X;  4M6J A;  5HQZ A;  3F0B X;  2HM9 A;  3RO9 A;  3K45 A;  3UM8 A;  1DDS A;  1KLK A;  1TDR A;  3F8Y A;  6DFR A;  1RX8 A;  3FL8 A;  2C2S A;  3SAI A;  2JYB A;  1DYH A;  1DHI A;  3ZPC A;  3DAT A;  4DFR A;  3IRN A;  3ROA A;  4KJK A;  3NTZ A;  1U72 A;  3NU0 A;  4PTJ A;  1RE7 A;  4PTH A;  1DR7 A;  5JA3 A;  3FRE X;  3QG2 A;  4ECK A;  4G8Z X;  3DL5 A;  3OAF A;  2QK8 A;  2OBC A;  3SRR X;  4HOG A;  2BLA A;  1DF7 A;  1JUV A;  2P4G A;  3TQA A;  1OHK A;  5E8Q A;  3NZB X;  3RG9 A;  4M6K A;  4M7V A;  5CCC A;  3S7A A;  4KY8 A;  4KY4 A;  1DG8 A;  2OIP A;  1RA1 A;  1DRF A;  1DLR A;  1HFR A;  3NXX A;  5ECX A;  3KJR A;  3K47 A;  4X5J A;  1JOL A;  4ELH A;  4QLF A;  1E26 A;  4KYA A;  4IXG X;  3N0H A;  3HJ3 A;  3F0U X;  2DHF A;  5DXV A;  1RX9 A;  4KD7 A;  3QLZ A;  3NXR A;  1DLS A;  3GYF A;  3KJS A;  4PST A;  1KMS A;  5HSU A;  4KFJ A;  1J3J A;  3D84 X;  3FYV X;  2G6V A;  2W3B A;  3SA1 A;  3FYW X;  4GH8 A;  1RX1 A;  2ITH A;  5HF0 X;  2D0K A;  4XT5 A;  1RX4 A;  2GD9 A;  1RX2 A;  4H95 A;  3SA2 A;  4KL9 A;  1S3W A;  2XW7 A;  4NX6 A;  1RG7 A;  4ELE A;  3SH2 A;  1RC4 A;  4HOE A;  3S3V A;  2BLC A;  3I8A X;  4ELF A;  4M6L A;  1D1G A;  3F0Q X;  4PDJ A;  1DRA A;  1AI9 A;  1J3K A;  5HSR A;  3EIG A;  1S3V A;  2FZH A;  5HQY A;  3FQC A;  3JWF A;  4H98 A;  1MVT A;  2C2T A;  4Q0D A;  4KNE A;  4KM2 A;  3EEM A;  1IA4 A;  1DIS A;  4KLX A;  3NXT A;  3K74 A;  2FZI A;  4FGG A;  5HT4 A;  3QLY A;  5EAJ A;  2O7P A;  3CL9 A;  1DRB A;  2W9H A;  2DRC A;  3NXO A;  3QL0 A;  2ANO A;  1IA2 A;  5U27 A;  4XT6 A;  5HPB A;  1J3I A;  1SEJ A;  1RA8 A;  4X5G A;  3JW3 A;  4ELB A;  1VDR A;  1DDR A;  3F0V X;  3EEJ A;  4X5H A;  1PD9 A;  7DFR A;  2H2Q A;  1DYJ A;  2D5N A;  1RX5 A;  4G95 A;  2HQP A;  3NXV A;  2W3V A;  3FQF A;  3JWC A;  3DFR A;  2B3Z A;  1DHF A;  4M7U A;  3SRS X;  3EEK A;  1ZDR A;  1IA1 A;  1DR5 A;  3FQZ A;  3I3R A;  1HFP A;  4QJC A;  3K2H A;  3QGT A;  2W3M A;  4LAE X;  1LUD A;  3DG8 A;  4P3R A;  4P66 A;  4QLG A;  3FY8 X;  3QLR A;  3FQO A;  3JWK A;  3KGY A;  4XT7 A;  1DIU A;  3NZ6 X;  3NXY A;  3Q1H A;  4XEC X;  3IRM A;  3DRC A;  1DG5 A;  4G3M A;  1MVS A;  3FRD X;  3FS6 A;  2CIG A;  1U70 A;  3KY8 A;  3NRR A;  5DFR A;  1RX7 A;  4I1N A;  3SQY X;  1CD2 A;  1HFQ A;  4DP3 A;  3GHC A;  5FDA A;  3F8Z A;  3NZ9 X;  4KJL A;  1AO8 A;  4KEB A;  3FL9 A;  1M7A A;  3S9U A;  4H96 A;  4Q0E A;  5HUI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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