5I3MA

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated thiourea-linked carboxylate zinc-chelator water-soluble inhibitor (dc31).
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
157
structure length
157
Chain Sequence
PVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 48
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i3mA00
3HDAP 2OW9A 4GQLA 1EUBA 2YIGA 3NX7A 3Q2HA 1J7NA 1QICA 4WKIA 1I73A 1MMPA 2WO8A 1Y8JA 4J4MA 1AKLA 3ZVSA 3CKIA 1IABA 1UMTA 1KUKA 1QIBA 3ZXHA 1YP1A 4A7BA 3HBUP 3LKAA 4JQGA 4XM7A 1D5JA 3MA2A 3I7GA 3V96B 1Z3JA 3Q2GA 2N8RA 1WNIA 2Y6CA 1G9KA 1K7GA 4H49A 4ILWD 3LILA 4CTHA 3DSLA 1XUDA 2OXZA 2SRTA 1OS2A 1FM1A 2W0DA 4PKRA 4R3VA 3HY7A 1OM6A 1XFXA 1K7QA 3LGPA 4WK7A 4IN9A 2OXWA 3DWBA 1SMPA 1AF0A 3F19A 2OY2A 1XFZA 3LUNA 4JP4A 1O0QA 2POJA 5I43A 3LIKA 3LQBA 1FBLA 2JNPA 2CLTA 5I4OA 1XFWA 4I35A 1BM6A 2YB9A 2HU6A 4PKWA 1JKYA 1HY7A 4G9LA 2USNA 1BQQM 1IAGA 1ZTQA 4G0DA 4ZR5A 2ERQA 1CGFA 3KEJA 3BA0A 1PWWA 2DDFA 2RJQA 4FU4A 1SRPA 3LE9A 1B3DA 2X7MA 1R1IA 1BUDA 3LEAA 2RJPA 3HB2P 3K7NA 2XS3A 3G5CA 1IADA 1L6JA 2KRJA 1XFVA 3LIRA 3N2VA 1OM8A 1R1JA 2V4BA 3DNGA 3K7LA 3O2XA 2FV5A 5D1TA 4DD8A 1QUAA 2OZRA 5CZMA 5D1UA 5B5PA 1PWUA 1C8TA 1JH1A 4Q1LA 2K2GA 1I76A 1MMRA 1YOUA 3EHXA 4AUOA 1I1IP 2TCLA 4PKSA 4IJOA 3VI1A 1GXDA 4H76A 2D1OA 4XM8A 3EDIA 1CGEA 1HFCA 5JMYA 4PKTA 3SHIA 1S4BP 3KHIA 1ROSA 1A85A 5D1SA 3F15A 2AYKA 5CXAA 5L7FA 4AXQA 2JIHA 3EDHA 3KECA 1QJIA 4L63A 1QIAA 3USNA 3F16A 3WV3A 1KUIA 2JSDA 1USNA 5BPAA 1SLNA 4WF6A 4H84A 1AYKA 5I3MA 1R55A 4GR3A 1JIZA 4JA1A 2MZIA 1ASTA 1BZSA 1BSWA 4JPAA 2DDYA 3I7IA 4DV8A 2JT5A 5D2BA 1KAPP 2FV9A 1ZS0A 2OI0A 3LMCA 2Z2DA 2OW2A 2X3CA 2D1NA 1BKCA 2O36A 1PWPA 3AYUA 3EWJA 5L79A 2PJTA 1QJJA 1XFYA 1YCMA 1HOVA 1KUGA 3EDGA 5BOTA 1YQYA 1Q3AA 4PKQA 4JIJA 1UTZA 1GE6A 2E3XA 1JJ9A 1RM8A 5BOYA 2OY4A 1BUVM 3B8ZA 3HBVP 3KEKA 1DTHA 1CGLA 1KUFA 2E2DA 5LABA 4H30A 4DF9A 3F17A 1BQOA 3B92A 3LJZA 3DPEA 1C3IA 1ZXCA 4WKEA 1R54A 2OW1A 3G42A 3EDZA 1GKCA 4H3XA 1HTDA 1UEAA 3HY9A 4L6TA 4FVLA 1XUCA 2XS4A 1CQRA 3LK8A 2Y6DA 1B8YA 3TT4A 1OM7A 3N2UA 1IAAA 4XM6A 2EROA 3TS4A 1D8FA 4XBHA 3TVCA 4I03A 1HV5A 1DMTA 1SU3A 3L0VA 2X3AA 5I2ZA 1A86A 1D8MA 3OHLA 3ELMA 1BKCI 966CA 1CXVA 1JANA 1ATLA 2W13A 4H82A 1RMZA 3UVCA 2MZHA 1GO8P 1JAQA 3LUMA 1C7KA 2J0TA 3HDBA 2K9CA 1GE5A 1CK7A 1KBCA 1G12A 3WV2A 4FXQA 1BKCE 3KMCA 456CA 2DW0A 4L19A 3F18A 4GR0A 3F1AA 3RTSA 2J83A 3P1VA 1JIWP 3VTGA 1MMQA 3P24A 1UMSA 1JAOA 3DPFA 3KWVC 4H1QA 2ERPA 1JAPA 1Y93A 2MZEA 2QPJA 1ZP5A 2OVXA 4GF1A 3OHOA 1OO9A 1EB6A 1PWQA 4FXYP 4H2EA 3O64A 1G49A 4AYKA 3RTTA 1Y0VA 2MLRA 2OVZA 4QKZA 5B5OA 3U1RA 1FLSA 3HYGA 1CAQA 4GWNA 3AIGA 3LJGA 4IUWA 2W14A 2DW2A 1HFSA 1OS9A 4AIGA 2L0RA 4PKUA 1GO7P 3GBOA 2A8HA 3B2ZA 2DW1A 3DL1A 5H8XA 3LQ0A 830CA 1SLMA 1GKDA 2JT6A 3TSKA 2CKIA 1ND1A 5D3CA 4HX3A 4GR8A 4HMAA 3EHYA 5D7WA 3WV1A 1R1HA 1BIWA 1MNCA 1K7IA 1OMJA 3KMEA 2MLSA 5CUHA 2OXUA 1G05A 2X3BA 1O0TA 1XURA 1KUHA 1XFUA 4PKVA 1UTTA 1IAEA 1SATA 2OW0A 2W15A 3KRYA 1ZXVA 4WZVA 3ZUKA 2I47A 4A3WA 3AYKA 1GE7A 3L0TA 1IACA 1CIZA 4DPEA 1PWVA 1JK3A 4GWMA 4ON1A 2O3EA 1ZVXA 1EAKA 1G4KA 3E8RA 2WO9A 1D7XA 2AIGP 4XCTA 2W12A 1H71P 4GUYA 3LJTA 4EFSA 1MMBA 5I12A 2WOAA 5I0LA
chains in the Genus database with same CATH superfamily
3HDAP 2OW9A 4GQLA 1EUBA 2YIGA 3NX7A 3Q2HA 1J7NA 1XAXA 1QICA 4WKIA 1I73A 1MMPA 2WO8A 1Y8JA 4J4MA 1AKLA 3ZVSA 3CKIA 1IABA 1UMTA 1KUKA 1QIBA 3ZXHA 1YP1A 4A7BA 3HBUP 3LKAA 4JQGA 2YUFA 4XM7A 1D5JA 3MA2A 3I7GA 3V96B 1Z3JA 3Q2GA 2N8RA 1WNIA 2Y6CA 1G9KA 1K7GA 4H49A 4ILWD 3LILA 4CTHA 3DSLA 1XUDA 2OXZA 2SRTA 1OS2A 1FM1A 2W0DA 4PKRA 4R3VA 3HY7A 3DTIA 1OM6A 1XFXA 1K7QA 3LGPA 4WK7A 4IN9A 2OXWA 3DWBA 1SMPA 1AF0A 3F19A 2OY2A 1XFZA 3LUNA 4JP4A 1O0QA 2POJA 5I43A 3LIKA 3LQBA 1FBLA 2JNPA 2CLTA 5I4OA 1XFWA 4I35A 1BM6A 2YB9A 2HU6A 4PKWA 1JKYA 1HY7A 4G9LA 2USNA 1BQQM 1IAGA 1ZTQA 4G0DA 4ZR5A 2ERQA 1CGFA 3KEJA 3BA0A 1PWWA 2DDFA 2RJQA 4FU4A 1SRPA 3LE9A 1B3DA 2X7MA 1R1IA 1BUDA 3LEAA 2RJPA 3HB2P 3K7NA 2XS3A 4L7AA 3G5CA 1IADA 1L6JA 2KRJA 1XFVA 3LIRA 3N2VA 1OM8A 1R1JA 2V4BA 3DNGA 3K7LA 3O2XA 2FV5A 5D1TA 4DD8A 1QUAA 2OZRA 5CZMA 5D1UA 5B5PA 1PWUA 1C8TA 1JH1A 4Q1LA 2K2GA 1I76A 1MMRA 1YOUA 3EHXA 4AUOA 1I1IP 2TCLA 4PKSA 4IJOA 3VI1A 1GXDA 4H76A 2D1OA 3DTKA 4XM8A 3EDIA 1CGEA 1HFCA 5JMYA 4PKTA 3SHIA 1S4BP 1TVIA 3KHIA 1ROSA 1A85A 5D1SA 3F15A 2AYKA 5CXAA 5L7FA 4AXQA 2JIHA 3EDHA 3KECA 1QJIA 4L63A 1QIAA 3USNA 3F16A 3WV3A 1KUIA 2JSDA 1USNA 5BPAA 1SLNA 4WF6A 4H84A 1AYKA 5I3MA 1R55A 4GR3A 1JIZA 4JA1A 3DTEA 2MZIA 1ASTA 1BZSA 1BSWA 4JPAA 2DDYA 3I7IA 4DV8A 2JT5A 5D2BA 1KAPP 2FV9A 1ZS0A 2OI0A 3LMCA 2Z2DA 2OW2A 2X3CA 2D1NA 1BKCA 2O36A 1PWPA 3AYUA 3EWJA 5L79A 2PJTA 1QJJA 1XFYA 1YCMA 1HOVA 1KUGA 3EDGA 5BOTA 1YQYA 1Q3AA 4PKQA 4JIJA 1UTZA 1GE6A 2E3XA 1JJ9A 1RM8A 5BOYA 2OY4A 1BUVM 3B8ZA 3HBVP 3KEKA 1DTHA 1CGLA 1KUFA 2E2DA 5LABA 4H30A 4DF9A 3F17A 1BQOA 3B92A 3LJZA 3DPEA 1C3IA 1ZXCA 4WKEA 1R54A 2OW1A 3G42A 3EDZA 1GKCA 4H3XA 1HTDA 1UEAA 3HY9A 4L6TA 4FVLA 1XUCA 2XS4A 1CQRA 3LK8A 2Y6DA 1B8YA 3TT4A 1OM7A 3N2UA 1IAAA 4XM6A 2EROA 3TS4A 1D8FA 4XBHA 3TVCA 4I03A 1HV5A 1DMTA 1SU3A 3L0VA 2X3AA 5I2ZA 1A86A 1D8MA 3OHLA 3ELMA 1BKCI 966CA 1CXVA 1JANA 1ATLA 2W13A 4H82A 1RMZA 3UVCA 2MZHA 1GO8P 1JAQA 3LUMA 1C7KA 2J0TA 3HDBA 2K9CA 1GE5A 1OZ9A 1CK7A 1KBCA 1G12A 3WV2A 4FXQA 1BKCE 3KMCA 456CA 2DW0A 4L19A 3F18A 4GR0A 3F1AA 3RTSA 2J83A 3P1VA 1JIWP 3VTGA 1MMQA 3P24A 1UMSA 1JAOA 3DPFA 3KWVC 4H1QA 2ERPA 1JAPA 1Y93A 2MZEA 2QPJA 1ZP5A 2OVXA 4GF1A 3OHOA 1OO9A 1EB6A 1PWQA 4FXYP 4H2EA 3O64A 1G49A 4AYKA 3RTTA 1Y0VA 2MLRA 2OVZA 4QKZA 5B5OA 3U1RA 1FLSA 3HYGA 1CAQA 4GWNA 3AIGA 3LJGA 4IUWA 2W14A 2DW2A 1HFSA 1OS9A 4AIGA 2L0RA 4PKUA 1GO7P 3GBOA 2A8HA 3B2ZA 2DW1A 3DL1A 5H8XA 3LQ0A 830CA 1SLMA 1GKDA 2JT6A 3TSKA 2CKIA 1ND1A 5D3CA 4HX3A 4GR8A 4HMAA 3EHYA 5D7WA 3WV1A 1R1HA 1BIWA 1MNCA 1K7IA 1OMJA 3KMEA 2MLSA 5CUHA 2OXUA 1G05A 2X3BA 1O0TA 1XURA 1KUHA 1XFUA 4PKVA 1UTTA 1IAEA 1SATA 2OW0A 2W15A 3KRYA 1ZXVA 4WZVA 3ZUKA 2I47A 4A3WA 3AYKA 1GE7A 3L0TA 1IACA 1CIZA 4DPEA 1PWVA 1JK3A 4GWMA 4ON1A 2O3EA 1ZVXA 1EAKA 1G4KA 1XM5A 3E8RA 2WO9A 1D7XA 2AIGP 4XCTA 2W12A 1H71P 4GUYA 3LJTA 4EFSA 1MMBA 5I12A 2WOAA 5I0LA
chains in the Genus database with same CATH topology
3HDAP 2OW9A 4GQLA 1EUBA 2YIGA 3NX7A 3Q2HA 1J7NA 1QICA 4WKIA 1I73A 1MMPA 2WO8A 1Y8JA 4J4MA 1AKLA 3ZVSA 3CKIA 1IABA 1UMTA 1KUKA 1QIBA 3ZXHA 1YP1A 4A7BA 3HBUP 3LKAA 4JQGA 2YUFA 4XM7A 1D5JA 3MA2A 3I7GA 3V96B 1Z3JA 3Q2GA 2N8RA 1WNIA 2Y6CA 1G9KA 1K7GA 4H49A 4ILWD 3LILA 4CTHA 3DSLA 1XUDA 2OXZA 2SRTA 1OS2A 1FM1A 2W0DA 4PKRA 4R3VA 3HY7A 3DTIA 1OM6A 1XFXA 1K7QA 3LGPA 4WK7A 4IN9A 2OXWA 3DWBA 1SMPA 1AF0A 3F19A 2OY2A 1XFZA 3LUNA 4JP4A 1O0QA 2POJA 5I43A 3LIKA 3LQBA 1FBLA 2JNPA 2CLTA 5I4OA 1XFWA 4I35A 1BM6A 2YB9A 2HU6A 4PKWA 1JKYA 1HY7A 4G9LA 2USNA 1BQQM 1IAGA 1ZTQA 4G0DA 4ZR5A 2ERQA 1CGFA 3KEJA 3BA0A 1PWWA 2DDFA 2RJQA 4FU4A 1SRPA 3LE9A 1B3DA 2X7MA 1R1IA 1BUDA 3LEAA 2RJPA 3HB2P 3K7NA 2XS3A 4L7AA 3G5CA 1IADA 1L6JA 2KRJA 1XFVA 3LIRA 3N2VA 1OM8A 1R1JA 2V4BA 3DNGA 3K7LA 3O2XA 2FV5A 5D1TA 4DD8A 1QUAA 2OZRA 5CZMA 5D1UA 5B5PA 1PWUA 1C8TA 1JH1A 4Q1LA 2K2GA 1I76A 1MMRA 1YOUA 3EHXA 4AUOA 1I1IP 2TCLA 4PKSA 4IJOA 3VI1A 1GXDA 4H76A 2D1OA 3DTKA 4XM8A 3EDIA 1CGEA 1HFCA 5JMYA 4PKTA 3SHIA 1S4BP 3KHIA 1ROSA 1A85A 5D1SA 3F15A 2AYKA 5CXAA 5L7FA 4AXQA 2JIHA 3EDHA 3KECA 1QJIA 4L63A 1QIAA 3USNA 3F16A 3WV3A 1KUIA 2JSDA 1USNA 5BPAA 1SLNA 4WF6A 4H84A 1AYKA 5I3MA 1R55A 4GR3A 1JIZA 4JA1A 3DTEA 2MZIA 1ASTA 1BZSA 1BSWA 4JPAA 2DDYA 3I7IA 4DV8A 2JT5A 5D2BA 1KAPP 2FV9A 1ZS0A 2OI0A 3LMCA 2Z2DA 2OW2A 2X3CA 2D1NA 1BKCA 2O36A 1PWPA 3AYUA 3EWJA 5L79A 2PJTA 1QJJA 1XFYA 1YCMA 1HOVA 1KUGA 3EDGA 5BOTA 1YQYA 1Q3AA 4PKQA 4JIJA 1UTZA 1GE6A 2E3XA 1JJ9A 1RM8A 5BOYA 2OY4A 1BUVM 3B8ZA 3HBVP 3KEKA 1DTHA 1CGLA 1KUFA 2E2DA 5LABA 4H30A 4DF9A 3F17A 1BQOA 3B92A 3LJZA 3DPEA 1C3IA 1ZXCA 4WKEA 1R54A 2OW1A 3G42A 3EDZA 1GKCA 4H3XA 1HTDA 1UEAA 3HY9A 4L6TA 4FVLA 1XUCA 2XS4A 1CQRA 3LK8A 2Y6DA 1B8YA 3TT4A 1OM7A 3N2UA 1IAAA 4XM6A 2EROA 3TS4A 1D8FA 4XBHA 3TVCA 4I03A 1HV5A 1DMTA 1SU3A 3L0VA 2X3AA 5I2ZA 1A86A 1D8MA 3OHLA 3ELMA 1BKCI 966CA 1CXVA 1JANA 1ATLA 2W13A 4H82A 1RMZA 3UVCA 2MZHA 1GO8P 1JAQA 3LUMA 1C7KA 2J0TA 3HDBA 2K9CA 1GE5A 1CK7A 1KBCA 1G12A 3WV2A 4FXQA 1BKCE 3KMCA 456CA 2DW0A 4L19A 3F18A 4GR0A 3F1AA 3RTSA 2J83A 3P1VA 1JIWP 3VTGA 1MMQA 3P24A 1UMSA 1JAOA 3DPFA 3KWVC 4H1QA 2ERPA 1JAPA 1Y93A 2MZEA 2QPJA 1ZP5A 2OVXA 4GF1A 3OHOA 1OO9A 1EB6A 1PWQA 4FXYP 4H2EA 3O64A 1G49A 4AYKA 3RTTA 1Y0VA 2MLRA 2OVZA 4QKZA 5B5OA 3U1RA 1FLSA 3HYGA 1CAQA 4GWNA 3AIGA 3LJGA 4IUWA 2W14A 2DW2A 1HFSA 1OS9A 4AIGA 2L0RA 4PKUA 1GO7P 3GBOA 2A8HA 3B2ZA 2DW1A 3DL1A 5H8XA 3LQ0A 830CA 1SLMA 1GKDA 2JT6A 3TSKA 2CKIA 1ND1A 5D3CA 4HX3A 4GR8A 4HMAA 3EHYA 5D7WA 3WV1A 1R1HA 1BIWA 1MNCA 1K7IA 1OMJA 3KMEA 2MLSA 5CUHA 2OXUA 1G05A 2X3BA 1O0TA 1XURA 1KUHA 1XFUA 4PKVA 1UTTA 1IAEA 1SATA 2OW0A 2W15A 3KRYA 1ZXVA 4WZVA 3ZUKA 2I47A 4A3WA 3AYKA 1GE7A 3L0TA 1IACA 1CIZA 4DPEA 1PWVA 1JK3A 4GWMA 4ON1A 2O3EA 1ZVXA 1EAKA 1G4KA 3E8RA 2WO9A 1D7XA 2AIGP 4XCTA 2W12A 1H71P 4GUYA 3LJTA 4EFSA 1MMBA 5I12A 2WOAA 5I0LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HDA P;  2OW9 A;  4GQL A;  1EUB A;  2YIG A;  3NX7 A;  3Q2H A;  1J7N A;  1QIC A;  4WKI A;  1I73 A;  1MMP A;  2WO8 A;  1Y8J A;  4J4M A;  1AKL A;  3ZVS A;  3CKI A;  1IAB A;  1UMT A;  1KUK A;  1QIB A;  3ZXH A;  1YP1 A;  4A7B A;  3HBU P;  3LKA A;  4JQG A;  4XM7 A;  1D5J A;  3MA2 A;  3I7G A;  3V96 B;  1Z3J A;  3Q2G A;  2N8R A;  1WNI A;  2Y6C A;  1G9K A;  1K7G A;  4H49 A;  4ILW D;  3LIL A;  4CTH A;  3DSL A;  1XUD A;  2OXZ A;  2SRT A;  1OS2 A;  1FM1 A;  2W0D A;  4PKR A;  4R3V A;  3HY7 A;  1OM6 A;  1XFX A;  1K7Q A;  3LGP A;  4WK7 A;  4IN9 A;  2OXW A;  3DWB A;  1SMP A;  1AF0 A;  3F19 A;  2OY2 A;  1XFZ A;  3LUN A;  4JP4 A;  1O0Q A;  2POJ A;  5I43 A;  3LIK A;  3LQB A;  1FBL A;  2JNP A;  2CLT A;  5I4O A;  1XFW A;  4I35 A;  1BM6 A;  2YB9 A;  2HU6 A;  4PKW A;  1JKY A;  1HY7 A;  4G9L A;  2USN A;  1BQQ M;  1IAG A;  1ZTQ A;  4G0D A;  4ZR5 A;  2ERQ A;  1CGF A;  3KEJ A;  3BA0 A;  1PWW A;  2DDF A;  2RJQ A;  4FU4 A;  1SRP A;  3LE9 A;  1B3D A;  2X7M A;  1R1I A;  1BUD A;  3LEA A;  2RJP A;  3HB2 P;  3K7N A;  2XS3 A;  3G5C A;  1IAD A;  1L6J A;  2KRJ A;  1XFV A;  3LIR A;  3N2V A;  1OM8 A;  1R1J A;  2V4B A;  3DNG A;  3K7L A;  3O2X A;  2FV5 A;  5D1T A;  4DD8 A;  1QUA A;  2OZR A;  5CZM A;  5D1U A;  5B5P A;  1PWU A;  1C8T A;  1JH1 A;  4Q1L A;  2K2G A;  1I76 A;  1MMR A;  1YOU A;  3EHX A;  4AUO A;  1I1I P;  2TCL A;  4PKS A;  4IJO A;  3VI1 A;  1GXD A;  4H76 A;  2D1O A;  4XM8 A;  3EDI A;  1CGE A;  1HFC A;  5JMY A;  4PKT A;  3SHI A;  1S4B P;  3KHI A;  1ROS A;  1A85 A;  5D1S A;  3F15 A;  2AYK A;  5CXA A;  5L7F A;  4AXQ A;  2JIH A;  3EDH A;  3KEC A;  1QJI A;  4L63 A;  1QIA A;  3USN A;  3F16 A;  3WV3 A;  1KUI A;  2JSD A;  1USN A;  5BPA A;  1SLN A;  4WF6 A;  4H84 A;  1AYK A;  5I3M A;  1R55 A;  4GR3 A;  1JIZ A;  4JA1 A;  2MZI A;  1AST A;  1BZS A;  1BSW A;  4JPA A;  2DDY A;  3I7I A;  4DV8 A;  2JT5 A;  5D2B A;  1KAP P;  2FV9 A;  1ZS0 A;  2OI0 A;  3LMC A;  2Z2D A;  2OW2 A;  2X3C A;  2D1N A;  1BKC A;  2O36 A;  1PWP A;  3AYU A;  3EWJ A;  5L79 A;  2PJT A;  1QJJ A;  1XFY A;  1YCM A;  1HOV A;  1KUG A;  3EDG A;  5BOT A;  1YQY A;  1Q3A A;  4PKQ A;  4JIJ A;  1UTZ A;  1GE6 A;  2E3X A;  1JJ9 A;  1RM8 A;  5BOY A;  2OY4 A;  1BUV M;  3B8Z A;  3HBV P;  3KEK A;  1DTH A;  1CGL A;  1KUF A;  2E2D A;  5LAB A;  4H30 A;  4DF9 A;  3F17 A;  1BQO A;  3B92 A;  3LJZ A;  3DPE A;  1C3I A;  1ZXC A;  4WKE A;  1R54 A;  2OW1 A;  3G42 A;  3EDZ A;  1GKC A;  4H3X A;  1HTD A;  1UEA A;  3HY9 A;  4L6T A;  4FVL A;  1XUC A;  2XS4 A;  1CQR A;  3LK8 A;  2Y6D A;  1B8Y A;  3TT4 A;  1OM7 A;  3N2U A;  1IAA A;  4XM6 A;  2ERO A;  3TS4 A;  1D8F A;  4XBH A;  3TVC A;  4I03 A;  1HV5 A;  1DMT A;  1SU3 A;  3L0V A;  2X3A A;  5I2Z A;  1A86 A;  1D8M A;  3OHL A;  3ELM A;  1BKC I;  966C A;  1CXV A;  1JAN A;  1ATL A;  2W13 A;  4H82 A;  1RMZ A;  3UVC A;  2MZH A;  1GO8 P;  1JAQ A;  3LUM A;  1C7K A;  2J0T A;  3HDB A;  2K9C A;  1GE5 A;  1CK7 A;  1KBC A;  1G12 A;  3WV2 A;  4FXQ A;  1BKC E;  3KMC A;  456C A;  2DW0 A;  4L19 A;  3F18 A;  4GR0 A;  3F1A A;  3RTS A;  2J83 A;  3P1V A;  1JIW P;  3VTG A;  1MMQ A;  3P24 A;  1UMS A;  1JAO A;  3DPF A;  3KWV C;  4H1Q A;  2ERP A;  1JAP A;  1Y93 A;  2MZE A;  2QPJ A;  1ZP5 A;  2OVX A;  4GF1 A;  3OHO A;  1OO9 A;  1EB6 A;  1PWQ A;  4FXY P;  4H2E A;  3O64 A;  1G49 A;  4AYK A;  3RTT A;  1Y0V A;  2MLR A;  2OVZ A;  4QKZ A;  5B5O A;  3U1R A;  1FLS A;  3HYG A;  1CAQ A;  4GWN A;  3AIG A;  3LJG A;  4IUW A;  2W14 A;  2DW2 A;  1HFS A;  1OS9 A;  4AIG A;  2L0R A;  4PKU A;  1GO7 P;  3GBO A;  2A8H A;  3B2Z A;  2DW1 A;  3DL1 A;  5H8X A;  3LQ0 A;  830C A;  1SLM A;  1GKD A;  2JT6 A;  3TSK A;  2CKI A;  1ND1 A;  5D3C A;  4HX3 A;  4GR8 A;  4HMA A;  3EHY A;  5D7W A;  3WV1 A;  1R1H A;  1BIW A;  1MNC A;  1K7I A;  1OMJ A;  3KME A;  2MLS A;  5CUH A;  2OXU A;  1G05 A;  2X3B A;  1O0T A;  1XUR A;  1KUH A;  1XFU A;  4PKV A;  1UTT A;  1IAE A;  1SAT A;  2OW0 A;  2W15 A;  3KRY A;  1ZXV A;  4WZV A;  3ZUK A;  2I47 A;  4A3W A;  3AYK A;  1GE7 A;  3L0T A;  1IAC A;  1CIZ A;  4DPE A;  1PWV A;  1JK3 A;  4GWM A;  4ON1 A;  2O3E A;  1ZVX A;  1EAK A;  1G4K A;  3E8R A;  2WO9 A;  1D7X A;  2AIG P;  4XCT A;  2W12 A;  1H71 P;  4GUY A;  3LJT A;  4EFS A;  1MMB A;  5I12 A;  2WOA A;  5I0L A; 
#chains in the Genus database with same CATH topology
 3HDA P;  2OW9 A;  4GQL A;  1EUB A;  2YIG A;  3NX7 A;  3Q2H A;  1J7N A;  1XAX A;  1QIC A;  4WKI A;  1I73 A;  1MMP A;  2WO8 A;  1Y8J A;  4J4M A;  1AKL A;  3ZVS A;  3CKI A;  1IAB A;  1UMT A;  1KUK A;  1QIB A;  3ZXH A;  1YP1 A;  4A7B A;  3HBU P;  3LKA A;  4JQG A;  2YUF A;  4XM7 A;  1D5J A;  3MA2 A;  3I7G A;  3V96 B;  1Z3J A;  3Q2G A;  2N8R A;  1WNI A;  2Y6C A;  1G9K A;  1K7G A;  4H49 A;  4ILW D;  3LIL A;  4CTH A;  3DSL A;  1XUD A;  2OXZ A;  2SRT A;  1OS2 A;  1FM1 A;  2W0D A;  4PKR A;  4R3V A;  3HY7 A;  3DTI A;  1OM6 A;  1XFX A;  1K7Q A;  3LGP A;  4WK7 A;  4IN9 A;  2OXW A;  3DWB A;  1SMP A;  1AF0 A;  3F19 A;  2OY2 A;  1XFZ A;  3LUN A;  4JP4 A;  1O0Q A;  2POJ A;  5I43 A;  3LIK A;  3LQB A;  1FBL A;  2JNP A;  2CLT A;  5I4O A;  1XFW A;  4I35 A;  1BM6 A;  2YB9 A;  2HU6 A;  4PKW A;  1JKY A;  1HY7 A;  4G9L A;  2USN A;  1BQQ M;  1IAG A;  1ZTQ A;  4G0D A;  4ZR5 A;  2ERQ A;  1CGF A;  3KEJ A;  3BA0 A;  1PWW A;  2DDF A;  2RJQ A;  4FU4 A;  1SRP A;  3LE9 A;  1B3D A;  2X7M A;  1R1I A;  1BUD A;  3LEA A;  2RJP A;  3HB2 P;  3K7N A;  2XS3 A;  4L7A A;  3G5C A;  1IAD A;  1L6J A;  2KRJ A;  1XFV A;  3LIR A;  3N2V A;  1OM8 A;  1R1J A;  2V4B A;  3DNG A;  3K7L A;  3O2X A;  2FV5 A;  5D1T A;  4DD8 A;  1QUA A;  2OZR A;  5CZM A;  5D1U A;  5B5P A;  1PWU A;  1C8T A;  1JH1 A;  4Q1L A;  2K2G A;  1I76 A;  1MMR A;  1YOU A;  3EHX A;  4AUO A;  1I1I P;  2TCL A;  4PKS A;  4IJO A;  3VI1 A;  1GXD A;  4H76 A;  2D1O A;  3DTK A;  4XM8 A;  3EDI A;  1CGE A;  1HFC A;  5JMY A;  4PKT A;  3SHI A;  1S4B P;  1TVI A;  3KHI A;  1ROS A;  1A85 A;  5D1S A;  3F15 A;  2AYK A;  5CXA A;  5L7F A;  4AXQ A;  2JIH A;  3EDH A;  3KEC A;  1QJI A;  4L63 A;  1QIA A;  3USN A;  3F16 A;  3WV3 A;  1KUI A;  2JSD A;  1USN A;  5BPA A;  1SLN A;  4WF6 A;  4H84 A;  1AYK A;  5I3M A;  1R55 A;  4GR3 A;  1JIZ A;  4JA1 A;  3DTE A;  2MZI A;  1AST A;  1BZS A;  1BSW A;  4JPA A;  2DDY A;  3I7I A;  4DV8 A;  2JT5 A;  5D2B A;  1KAP P;  2FV9 A;  1ZS0 A;  2OI0 A;  3LMC A;  2Z2D A;  2OW2 A;  2X3C A;  2D1N A;  1BKC A;  2O36 A;  1PWP A;  3AYU A;  3EWJ A;  5L79 A;  2PJT A;  1QJJ A;  1XFY A;  1YCM A;  1HOV A;  1KUG A;  3EDG A;  5BOT A;  1YQY A;  1Q3A A;  4PKQ A;  4JIJ A;  1UTZ A;  1GE6 A;  2E3X A;  1JJ9 A;  1RM8 A;  5BOY A;  2OY4 A;  1BUV M;  3B8Z A;  3HBV P;  3KEK A;  1DTH A;  1CGL A;  1KUF A;  2E2D A;  5LAB A;  4H30 A;  4DF9 A;  3F17 A;  1BQO A;  3B92 A;  3LJZ A;  3DPE A;  1C3I A;  1ZXC A;  4WKE A;  1R54 A;  2OW1 A;  3G42 A;  3EDZ A;  1GKC A;  4H3X A;  1HTD A;  1UEA A;  3HY9 A;  4L6T A;  4FVL A;  1XUC A;  2XS4 A;  1CQR A;  3LK8 A;  2Y6D A;  1B8Y A;  3TT4 A;  1OM7 A;  3N2U A;  1IAA A;  4XM6 A;  2ERO A;  3TS4 A;  1D8F A;  4XBH A;  3TVC A;  4I03 A;  1HV5 A;  1DMT A;  1SU3 A;  3L0V A;  2X3A A;  5I2Z A;  1A86 A;  1D8M A;  3OHL A;  3ELM A;  1BKC I;  966C A;  1CXV A;  1JAN A;  1ATL A;  2W13 A;  4H82 A;  1RMZ A;  3UVC A;  2MZH A;  1GO8 P;  1JAQ A;  3LUM A;  1C7K A;  2J0T A;  3HDB A;  2K9C A;  1GE5 A;  1OZ9 A;  1CK7 A;  1KBC A;  1G12 A;  3WV2 A;  4FXQ A;  1BKC E;  3KMC A;  456C A;  2DW0 A;  4L19 A;  3F18 A;  4GR0 A;  3F1A A;  3RTS A;  2J83 A;  3P1V A;  1JIW P;  3VTG A;  1MMQ A;  3P24 A;  1UMS A;  1JAO A;  3DPF A;  3KWV C;  4H1Q A;  2ERP A;  1JAP A;  1Y93 A;  2MZE A;  2QPJ A;  1ZP5 A;  2OVX A;  4GF1 A;  3OHO A;  1OO9 A;  1EB6 A;  1PWQ A;  4FXY P;  4H2E A;  3O64 A;  1G49 A;  4AYK A;  3RTT A;  1Y0V A;  2MLR A;  2OVZ A;  4QKZ A;  5B5O A;  3U1R A;  1FLS A;  3HYG A;  1CAQ A;  4GWN A;  3AIG A;  3LJG A;  4IUW A;  2W14 A;  2DW2 A;  1HFS A;  1OS9 A;  4AIG A;  2L0R A;  4PKU A;  1GO7 P;  3GBO A;  2A8H A;  3B2Z A;  2DW1 A;  3DL1 A;  5H8X A;  3LQ0 A;  830C A;  1SLM A;  1GKD A;  2JT6 A;  3TSK A;  2CKI A;  1ND1 A;  5D3C A;  4HX3 A;  4GR8 A;  4HMA A;  3EHY A;  5D7W A;  3WV1 A;  1R1H A;  1BIW A;  1MNC A;  1K7I A;  1OMJ A;  3KME A;  2MLS A;  5CUH A;  2OXU A;  1G05 A;  2X3B A;  1O0T A;  1XUR A;  1KUH A;  1XFU A;  4PKV A;  1UTT A;  1IAE A;  1SAT A;  2OW0 A;  2W15 A;  3KRY A;  1ZXV A;  4WZV A;  3ZUK A;  2I47 A;  4A3W A;  3AYK A;  1GE7 A;  3L0T A;  1IAC A;  1CIZ A;  4DPE A;  1PWV A;  1JK3 A;  4GWM A;  4ON1 A;  2O3E A;  1ZVX A;  1EAK A;  1G4K A;  1XM5 A;  3E8R A;  2WO9 A;  1D7X A;  2AIG P;  4XCT A;  2W12 A;  1H71 P;  4GUY A;  3LJT A;  4EFS A;  1MMB A;  5I12 A;  2WOA A;  5I0L A; 
#chains in the Genus database with same CATH homology
 3HDA P;  2OW9 A;  4GQL A;  1EUB A;  2YIG A;  3NX7 A;  3Q2H A;  1J7N A;  1QIC A;  4WKI A;  1I73 A;  1MMP A;  2WO8 A;  1Y8J A;  4J4M A;  1AKL A;  3ZVS A;  3CKI A;  1IAB A;  1UMT A;  1KUK A;  1QIB A;  3ZXH A;  1YP1 A;  4A7B A;  3HBU P;  3LKA A;  4JQG A;  2YUF A;  4XM7 A;  1D5J A;  3MA2 A;  3I7G A;  3V96 B;  1Z3J A;  3Q2G A;  2N8R A;  1WNI A;  2Y6C A;  1G9K A;  1K7G A;  4H49 A;  4ILW D;  3LIL A;  4CTH A;  3DSL A;  1XUD A;  2OXZ A;  2SRT A;  1OS2 A;  1FM1 A;  2W0D A;  4PKR A;  4R3V A;  3HY7 A;  3DTI A;  1OM6 A;  1XFX A;  1K7Q A;  3LGP A;  4WK7 A;  4IN9 A;  2OXW A;  3DWB A;  1SMP A;  1AF0 A;  3F19 A;  2OY2 A;  1XFZ A;  3LUN A;  4JP4 A;  1O0Q A;  2POJ A;  5I43 A;  3LIK A;  3LQB A;  1FBL A;  2JNP A;  2CLT A;  5I4O A;  1XFW A;  4I35 A;  1BM6 A;  2YB9 A;  2HU6 A;  4PKW A;  1JKY A;  1HY7 A;  4G9L A;  2USN A;  1BQQ M;  1IAG A;  1ZTQ A;  4G0D A;  4ZR5 A;  2ERQ A;  1CGF A;  3KEJ A;  3BA0 A;  1PWW A;  2DDF A;  2RJQ A;  4FU4 A;  1SRP A;  3LE9 A;  1B3D A;  2X7M A;  1R1I A;  1BUD A;  3LEA A;  2RJP A;  3HB2 P;  3K7N A;  2XS3 A;  4L7A A;  3G5C A;  1IAD A;  1L6J A;  2KRJ A;  1XFV A;  3LIR A;  3N2V A;  1OM8 A;  1R1J A;  2V4B A;  3DNG A;  3K7L A;  3O2X A;  2FV5 A;  5D1T A;  4DD8 A;  1QUA A;  2OZR A;  5CZM A;  5D1U A;  5B5P A;  1PWU A;  1C8T A;  1JH1 A;  4Q1L A;  2K2G A;  1I76 A;  1MMR A;  1YOU A;  3EHX A;  4AUO A;  1I1I P;  2TCL A;  4PKS A;  4IJO A;  3VI1 A;  1GXD A;  4H76 A;  2D1O A;  3DTK A;  4XM8 A;  3EDI A;  1CGE A;  1HFC A;  5JMY A;  4PKT A;  3SHI A;  1S4B P;  3KHI A;  1ROS A;  1A85 A;  5D1S A;  3F15 A;  2AYK A;  5CXA A;  5L7F A;  4AXQ A;  2JIH A;  3EDH A;  3KEC A;  1QJI A;  4L63 A;  1QIA A;  3USN A;  3F16 A;  3WV3 A;  1KUI A;  2JSD A;  1USN A;  5BPA A;  1SLN A;  4WF6 A;  4H84 A;  1AYK A;  5I3M A;  1R55 A;  4GR3 A;  1JIZ A;  4JA1 A;  3DTE A;  2MZI A;  1AST A;  1BZS A;  1BSW A;  4JPA A;  2DDY A;  3I7I A;  4DV8 A;  2JT5 A;  5D2B A;  1KAP P;  2FV9 A;  1ZS0 A;  2OI0 A;  3LMC A;  2Z2D A;  2OW2 A;  2X3C A;  2D1N A;  1BKC A;  2O36 A;  1PWP A;  3AYU A;  3EWJ A;  5L79 A;  2PJT A;  1QJJ A;  1XFY A;  1YCM A;  1HOV A;  1KUG A;  3EDG A;  5BOT A;  1YQY A;  1Q3A A;  4PKQ A;  4JIJ A;  1UTZ A;  1GE6 A;  2E3X A;  1JJ9 A;  1RM8 A;  5BOY A;  2OY4 A;  1BUV M;  3B8Z A;  3HBV P;  3KEK A;  1DTH A;  1CGL A;  1KUF A;  2E2D A;  5LAB A;  4H30 A;  4DF9 A;  3F17 A;  1BQO A;  3B92 A;  3LJZ A;  3DPE A;  1C3I A;  1ZXC A;  4WKE A;  1R54 A;  2OW1 A;  3G42 A;  3EDZ A;  1GKC A;  4H3X A;  1HTD A;  1UEA A;  3HY9 A;  4L6T A;  4FVL A;  1XUC A;  2XS4 A;  1CQR A;  3LK8 A;  2Y6D A;  1B8Y A;  3TT4 A;  1OM7 A;  3N2U A;  1IAA A;  4XM6 A;  2ERO A;  3TS4 A;  1D8F A;  4XBH A;  3TVC A;  4I03 A;  1HV5 A;  1DMT A;  1SU3 A;  3L0V A;  2X3A A;  5I2Z A;  1A86 A;  1D8M A;  3OHL A;  3ELM A;  1BKC I;  966C A;  1CXV A;  1JAN A;  1ATL A;  2W13 A;  4H82 A;  1RMZ A;  3UVC A;  2MZH A;  1GO8 P;  1JAQ A;  3LUM A;  1C7K A;  2J0T A;  3HDB A;  2K9C A;  1GE5 A;  1CK7 A;  1KBC A;  1G12 A;  3WV2 A;  4FXQ A;  1BKC E;  3KMC A;  456C A;  2DW0 A;  4L19 A;  3F18 A;  4GR0 A;  3F1A A;  3RTS A;  2J83 A;  3P1V A;  1JIW P;  3VTG A;  1MMQ A;  3P24 A;  1UMS A;  1JAO A;  3DPF A;  3KWV C;  4H1Q A;  2ERP A;  1JAP A;  1Y93 A;  2MZE A;  2QPJ A;  1ZP5 A;  2OVX A;  4GF1 A;  3OHO A;  1OO9 A;  1EB6 A;  1PWQ A;  4FXY P;  4H2E A;  3O64 A;  1G49 A;  4AYK A;  3RTT A;  1Y0V A;  2MLR A;  2OVZ A;  4QKZ A;  5B5O A;  3U1R A;  1FLS A;  3HYG A;  1CAQ A;  4GWN A;  3AIG A;  3LJG A;  4IUW A;  2W14 A;  2DW2 A;  1HFS A;  1OS9 A;  4AIG A;  2L0R A;  4PKU A;  1GO7 P;  3GBO A;  2A8H A;  3B2Z A;  2DW1 A;  3DL1 A;  5H8X A;  3LQ0 A;  830C A;  1SLM A;  1GKD A;  2JT6 A;  3TSK A;  2CKI A;  1ND1 A;  5D3C A;  4HX3 A;  4GR8 A;  4HMA A;  3EHY A;  5D7W A;  3WV1 A;  1R1H A;  1BIW A;  1MNC A;  1K7I A;  1OMJ A;  3KME A;  2MLS A;  5CUH A;  2OXU A;  1G05 A;  2X3B A;  1O0T A;  1XUR A;  1KUH A;  1XFU A;  4PKV A;  1UTT A;  1IAE A;  1SAT A;  2OW0 A;  2W15 A;  3KRY A;  1ZXV A;  4WZV A;  3ZUK A;  2I47 A;  4A3W A;  3AYK A;  1GE7 A;  3L0T A;  1IAC A;  1CIZ A;  4DPE A;  1PWV A;  1JK3 A;  4GWM A;  4ON1 A;  2O3E A;  1ZVX A;  1EAK A;  1G4K A;  3E8R A;  2WO9 A;  1D7X A;  2AIG P;  4XCT A;  2W12 A;  1H71 P;  4GUY A;  3LJT A;  4EFS A;  1MMB A;  5I12 A;  2WOA A;  5I0L A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...