5I43A

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (dc32).
Total Genus 46
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
157
structure length
157
Chain Sequence
PVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase
source organism Homo sapiens
total genus 46
structure length 157
sequence length 157
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i43A00
3VTGA 3L0VA 2OXUA 1Y93A 1BIWA 1OS2A 5B5OA 4DF9A 2MZEA 2AIGP 2Y6CA 3TSKA 5BOYA 2POJA 1R1HA 3EHYA 3HDBA 1HTDA 3I7GA 4GR3A 3V96B 2OZRA 3EDGA 1HY7A 1BQOA 2WOAA 1IADA 3HYGA 4JP4A 3Q2GA 4IJOA 2A8HA 5L79A 1QICA 4FU4A 1GE7A 1PWVA 4PKRA 2JT6A 1A85A 1YQYA 1JJ9A 3P1VA 1JAPA 3LGPA 1CIZA 4GWNA 3ZXHA 1OMJA 3EDHA 2X3BA 1CK7A 1MNCA 1C3IA 1QIAA 4H76A 1MMRA 2TCLA 1S4BP 1O0QA 3MA2A 3ZVSA 5D1SA 2CLTA 1OM8A 5H8XA 3F16A 4G0DA 4WF6A 1K7IA 1JK3A 3SHIA 2XS3A 3Q2HA 2DDFA 2OY2A 1YOUA 1BSWA 2OY4A 4FVLA 2DDYA 2OW1A 1FBLA 4GQLA 2OI0A 4L19A 1GE5A 4AYKA 1BUVM 3I7IA 3ELMA 2X7MA 1Q3AA 3LQBA 5I2ZA 1KUGA 3EDIA 4R3VA 2RJQA 4H84A 1MMQA 3AYUA 3WV3A 1DTHA 1ATLA 3GBOA 3BA0A 4DV8A 1KUHA 4IUWA 1CAQA 1BQQM 2N8RA 1IABA 4JQGA 4H3XA 4GUYA 1AYKA 4GR8A 4GF1A 3TT4A 3KMEA 4PKVA 2YB9A 1ZVXA 5D1UA 5LABA 1SATA 1FM1A 4H2EA 1USNA 2DW0A 4J4MA 5D2BA 4IN9A 1JH1A 1XFUA 1I73A 3AYKA 1AKLA 1GE6A 1PWWA 3DPEA 2MLSA 2OVZA 1BUDA 1GO8P 2X3AA 1QJJA 1ZS0A 1JIWP 1KBCA 3RTTA 4A3WA 2OW0A 3WV2A 1XFWA 4DD8A 3EDZA 4PKQA 1JAQA 2J0TA 1ND1A 2O36A 1CGLA 4DPEA 1I1IP 3P24A 2EROA 2PJTA 3F17A 1L6JA 1OM7A 1D8FA 1B8YA 1GKDA 2L0RA 3RTSA 1HFCA 4WZVA 3F1AA 3LE9A 4ILWD 1EB6A 1A86A 1R1IA 1RMZA 1ZXCA 2J83A 4XBHA 1JIZA 1ZTQA 3KEKA 4ON1A 5I4OA 966CA 2D1NA 1IAGA 456CA 5B5PA 1ASTA 1BKCA 2JNPA 3F19A 1KUIA 3OHLA 1HOVA 1EUBA 1ROSA 3LK8A 5CXAA 1BKCI 3LJGA 2DW2A 1UMTA 4AUOA 1SU3A 2WO8A 2JT5A 1EAKA 1J7NA 4GWMA 4WKIA 2ERPA 3KEJA 1XURA 1MMPA 3DSLA 3EWJA 5I3MA 4Q1LA 5L7FA 1PWQA 4WK7A 3AIGA 1JAOA 1OO9A 2O3EA 1IAEA 3B92A 3K7NA 1Z3JA 4XM6A 3KHIA 3F15A 4I35A 1DMTA 2W14A 2ERQA 1SLMA 1RM8A 4PKUA 4PKSA 5I0LA 1K7QA 1KUKA 1HV5A 2Y6DA 5D3CA 2Z2DA 1BM6A 3TS4A 3TVCA 4CTHA 5JMYA 1UEAA 1AF0A 3G42A 1Y8JA 5CUHA 1G12A 1SRPA 4GR0A 2OXZA 5BPAA 830CA 1R1JA 2QPJA 4JPAA 4PKTA 1KAPP 3HBUP 2V4BA 4H82A 1YP1A 2D1OA 3LQ0A 4AIGA 2W12A 1HFSA 2USNA 2OW9A 1GXDA 5I43A 4EFSA 1IAAA 3DWBA 3LKAA 4JIJA 4L6TA 5I12A 1OS9A 3HB2P 3LJTA 1C7KA 4XM7A 1D5JA 3EHXA 1GO7P 1XFZA 3KMCA 1O0TA 2K9CA 2WO9A 1XFYA 1C8TA 1JANA 1B3DA 2X3CA 2KRJA 3NX7A 3VI1A 4H30A 1I76A 3KECA 1KUFA 1UMSA 2AYKA 1YCMA 2W13A 4AXQA 3HDAP 1XUCA 3WV1A 1D7XA 1G9KA 2E3XA 2MZIA 3K7LA 3ZUKA 3G5CA 2FV5A 4XCTA 4HMAA 4HX3A 4WKEA 3KWVC 2E2DA 2MZHA 3OHOA 3F18A 1QUAA 2K2GA 2CKIA 1XFVA 4QKZA 4PKWA 3UVCA 1G49A 1WNIA 3B2ZA 4A7BA 2FV9A 1PWUA 1XUDA 1PWPA 4JA1A 4ZR5A 4XM8A 3O64A 3DL1A 2HU6A 1BZSA 3HBVP 4FXYP 1R54A 3U1RA 3LUNA 2XS4A 3O2XA 4G9LA 2SRTA 1SLNA 2RJPA 1K7GA 1JKYA 5CZMA 5D1TA 1GKCA 3LILA 5BOTA 3LJZA 3N2VA 2OW2A 3LMCA 1OM6A 1IACA 2I47A 2OVXA 1UTZA 3KRYA 1CQRA 4H1QA 5D7WA 3LIKA 4L63A 2W15A 1ZXVA 2YIGA 1QIBA 1D8MA 1CGEA 1G05A 3DPFA 1ZP5A 3B8ZA 3L0TA 1Y0VA 1FLSA 3USNA 4FXQA 2JIHA 3N2UA 3LIRA 3E8RA 1UTTA 3LUMA 4H49A 2MLRA 3HY9A 1CXVA 3DNGA 1CGFA 1G4KA 3CKIA 1XFXA 3HY7A 2OXWA 4I03A 1H71P 1MMBA 2JSDA 2DW1A 1QJIA 2W0DA 1R55A 1SMPA 3LEAA 1BKCE
chains in the Genus database with same CATH superfamily
3VTGA 3L0VA 2OXUA 1Y93A 1BIWA 1OS2A 5B5OA 4DF9A 2MZEA 2AIGP 2Y6CA 3TSKA 5BOYA 2POJA 1R1HA 3EHYA 3HDBA 1HTDA 3I7GA 4GR3A 3V96B 2OZRA 1XM5A 3EDGA 1HY7A 1BQOA 2WOAA 1IADA 3HYGA 4JP4A 3Q2GA 4IJOA 2A8HA 5L79A 1QICA 4FU4A 1GE7A 1PWVA 4PKRA 2JT6A 1A85A 1YQYA 1JJ9A 3P1VA 1JAPA 3LGPA 1CIZA 4GWNA 3ZXHA 1OMJA 3EDHA 2X3BA 1CK7A 1MNCA 1C3IA 1QIAA 4H76A 1MMRA 2TCLA 1S4BP 1O0QA 3MA2A 3ZVSA 5D1SA 2CLTA 1OM8A 5H8XA 3F16A 4G0DA 4WF6A 1K7IA 1JK3A 3SHIA 2XS3A 3Q2HA 2DDFA 2OY2A 1YOUA 1BSWA 2OY4A 4FVLA 2DDYA 2OW1A 1FBLA 4GQLA 2OI0A 4L19A 1GE5A 4AYKA 1BUVM 3I7IA 3ELMA 2X7MA 1Q3AA 3LQBA 5I2ZA 1KUGA 3EDIA 4R3VA 2RJQA 4H84A 1MMQA 3AYUA 3WV3A 1DTHA 1ATLA 3GBOA 3BA0A 4DV8A 1KUHA 4IUWA 1CAQA 1BQQM 2N8RA 1IABA 4JQGA 4H3XA 4GUYA 1AYKA 4GR8A 4GF1A 3TT4A 3KMEA 4PKVA 2YB9A 1ZVXA 5D1UA 5LABA 1SATA 1FM1A 4H2EA 1USNA 2DW0A 4J4MA 5D2BA 2YUFA 4IN9A 1JH1A 1XFUA 1I73A 3AYKA 1AKLA 1GE6A 1PWWA 3DPEA 2MLSA 2OVZA 1BUDA 1GO8P 2X3AA 1QJJA 1ZS0A 1JIWP 1KBCA 3RTTA 3DTIA 4A3WA 2OW0A 3WV2A 1XFWA 4DD8A 3EDZA 4PKQA 1JAQA 2J0TA 1ND1A 2O36A 1CGLA 4DPEA 1TVIA 3DTEA 1I1IP 1XAXA 3P24A 2EROA 2PJTA 3F17A 1L6JA 1OM7A 1D8FA 1B8YA 1GKDA 2L0RA 3RTSA 1HFCA 4WZVA 4L7AA 3F1AA 3LE9A 4ILWD 1EB6A 1A86A 1R1IA 1RMZA 1ZXCA 2J83A 4XBHA 1JIZA 1ZTQA 3KEKA 4ON1A 5I4OA 966CA 2D1NA 1IAGA 456CA 5B5PA 1ASTA 1BKCA 2JNPA 3F19A 1KUIA 3OHLA 1HOVA 1EUBA 1ROSA 3LK8A 5CXAA 1BKCI 3LJGA 2DW2A 1UMTA 4AUOA 1SU3A 2WO8A 2JT5A 1EAKA 3DTKA 1J7NA 4GWMA 4WKIA 2ERPA 3KEJA 1XURA 1MMPA 3DSLA 3EWJA 5I3MA 4Q1LA 5L7FA 1PWQA 4WK7A 3AIGA 1JAOA 1OO9A 2O3EA 1IAEA 3B92A 3K7NA 1Z3JA 4XM6A 3KHIA 3F15A 4I35A 1DMTA 2W14A 2ERQA 1SLMA 1RM8A 4PKUA 4PKSA 5I0LA 1K7QA 1KUKA 1HV5A 2Y6DA 5D3CA 2Z2DA 1BM6A 3TS4A 3TVCA 4CTHA 5JMYA 1UEAA 1AF0A 3G42A 1Y8JA 5CUHA 1G12A 1SRPA 4GR0A 2OXZA 5BPAA 830CA 1R1JA 2QPJA 4JPAA 4PKTA 1KAPP 3HBUP 2V4BA 4H82A 1YP1A 2D1OA 3LQ0A 4AIGA 2W12A 1HFSA 2USNA 2OW9A 1GXDA 5I43A 4EFSA 1IAAA 3DWBA 3LKAA 4JIJA 4L6TA 5I12A 1OS9A 3HB2P 3LJTA 1C7KA 4XM7A 1D5JA 3EHXA 1GO7P 1OZ9A 1XFZA 3KMCA 1O0TA 2K9CA 2WO9A 1XFYA 1C8TA 1JANA 1B3DA 2X3CA 2KRJA 3NX7A 3VI1A 4H30A 1I76A 3KECA 1KUFA 1UMSA 2AYKA 1YCMA 2W13A 4AXQA 3HDAP 1XUCA 3WV1A 1D7XA 1G9KA 2E3XA 2MZIA 3K7LA 3ZUKA 3G5CA 2FV5A 4XCTA 4HMAA 4HX3A 4WKEA 3KWVC 2E2DA 2MZHA 3OHOA 3F18A 1QUAA 2K2GA 2CKIA 1XFVA 4QKZA 4PKWA 3UVCA 1G49A 1WNIA 3B2ZA 4A7BA 2FV9A 1PWUA 1XUDA 1PWPA 4JA1A 4ZR5A 4XM8A 3O64A 3DL1A 2HU6A 1BZSA 3HBVP 4FXYP 1R54A 3U1RA 3LUNA 2XS4A 3O2XA 4G9LA 2SRTA 1SLNA 2RJPA 1K7GA 1JKYA 5CZMA 5D1TA 1GKCA 3LILA 5BOTA 3LJZA 3N2VA 2OW2A 3LMCA 1OM6A 1IACA 2I47A 2OVXA 1UTZA 3KRYA 1CQRA 4H1QA 5D7WA 3LIKA 4L63A 2W15A 1ZXVA 2YIGA 1QIBA 1D8MA 1CGEA 1G05A 3DPFA 1ZP5A 3B8ZA 3L0TA 1Y0VA 1FLSA 3USNA 4FXQA 2JIHA 3N2UA 3LIRA 3E8RA 1UTTA 3LUMA 4H49A 2MLRA 3HY9A 1CXVA 3DNGA 1CGFA 1G4KA 3CKIA 1XFXA 3HY7A 2OXWA 4I03A 1H71P 1MMBA 2JSDA 2DW1A 1QJIA 2W0DA 1R55A 1SMPA 3LEAA 1BKCE
chains in the Genus database with same CATH topology
3VTGA 3L0VA 2OXUA 1Y93A 1BIWA 1OS2A 5B5OA 4DF9A 2MZEA 2AIGP 2Y6CA 3TSKA 5BOYA 2POJA 1R1HA 3EHYA 3HDBA 1HTDA 3I7GA 4GR3A 3V96B 2OZRA 3EDGA 1HY7A 1BQOA 2WOAA 1IADA 3HYGA 4JP4A 3Q2GA 4IJOA 2A8HA 5L79A 1QICA 4FU4A 1GE7A 1PWVA 4PKRA 2JT6A 1A85A 1YQYA 1JJ9A 3P1VA 1JAPA 3LGPA 1CIZA 4GWNA 3ZXHA 1OMJA 3EDHA 2X3BA 1CK7A 1MNCA 1C3IA 1QIAA 4H76A 1MMRA 2TCLA 1S4BP 1O0QA 3MA2A 3ZVSA 5D1SA 2CLTA 1OM8A 5H8XA 3F16A 4G0DA 4WF6A 1K7IA 1JK3A 3SHIA 2XS3A 3Q2HA 2DDFA 2OY2A 1YOUA 1BSWA 2OY4A 4FVLA 2DDYA 2OW1A 1FBLA 4GQLA 2OI0A 4L19A 1GE5A 4AYKA 1BUVM 3I7IA 3ELMA 2X7MA 1Q3AA 3LQBA 5I2ZA 1KUGA 3EDIA 4R3VA 2RJQA 4H84A 1MMQA 3AYUA 3WV3A 1DTHA 1ATLA 3GBOA 3BA0A 4DV8A 1KUHA 4IUWA 1CAQA 1BQQM 2N8RA 1IABA 4JQGA 4H3XA 4GUYA 1AYKA 4GR8A 4GF1A 3TT4A 3KMEA 4PKVA 2YB9A 1ZVXA 5D1UA 5LABA 1SATA 1FM1A 4H2EA 1USNA 2DW0A 4J4MA 5D2BA 2YUFA 4IN9A 1JH1A 1XFUA 1I73A 3AYKA 1AKLA 1GE6A 1PWWA 3DPEA 2MLSA 2OVZA 1BUDA 1GO8P 2X3AA 1QJJA 1ZS0A 1JIWP 1KBCA 3RTTA 3DTIA 4A3WA 2OW0A 3WV2A 1XFWA 4DD8A 3EDZA 4PKQA 1JAQA 2J0TA 1ND1A 2O36A 1CGLA 4DPEA 3DTEA 1I1IP 3P24A 2EROA 2PJTA 3F17A 1L6JA 1OM7A 1D8FA 1B8YA 1GKDA 2L0RA 3RTSA 1HFCA 4WZVA 4L7AA 3F1AA 3LE9A 4ILWD 1EB6A 1A86A 1R1IA 1RMZA 1ZXCA 2J83A 4XBHA 1JIZA 1ZTQA 3KEKA 4ON1A 5I4OA 966CA 2D1NA 1IAGA 456CA 5B5PA 1ASTA 1BKCA 2JNPA 3F19A 1KUIA 3OHLA 1HOVA 1EUBA 1ROSA 3LK8A 5CXAA 1BKCI 3LJGA 2DW2A 1UMTA 4AUOA 1SU3A 2WO8A 2JT5A 1EAKA 3DTKA 1J7NA 4GWMA 4WKIA 2ERPA 3KEJA 1XURA 1MMPA 3DSLA 3EWJA 5I3MA 4Q1LA 5L7FA 1PWQA 4WK7A 3AIGA 1JAOA 1OO9A 2O3EA 1IAEA 3B92A 3K7NA 1Z3JA 4XM6A 3KHIA 3F15A 4I35A 1DMTA 2W14A 2ERQA 1SLMA 1RM8A 4PKUA 4PKSA 5I0LA 1K7QA 1KUKA 1HV5A 2Y6DA 5D3CA 2Z2DA 1BM6A 3TS4A 3TVCA 4CTHA 5JMYA 1UEAA 1AF0A 3G42A 1Y8JA 5CUHA 1G12A 1SRPA 4GR0A 2OXZA 5BPAA 830CA 1R1JA 2QPJA 4JPAA 4PKTA 1KAPP 3HBUP 2V4BA 4H82A 1YP1A 2D1OA 3LQ0A 4AIGA 2W12A 1HFSA 2USNA 2OW9A 1GXDA 5I43A 4EFSA 1IAAA 3DWBA 3LKAA 4JIJA 4L6TA 5I12A 1OS9A 3HB2P 3LJTA 1C7KA 4XM7A 1D5JA 3EHXA 1GO7P 1XFZA 3KMCA 1O0TA 2K9CA 2WO9A 1XFYA 1C8TA 1JANA 1B3DA 2X3CA 2KRJA 3NX7A 3VI1A 4H30A 1I76A 3KECA 1KUFA 1UMSA 2AYKA 1YCMA 2W13A 4AXQA 3HDAP 1XUCA 3WV1A 1D7XA 1G9KA 2E3XA 2MZIA 3K7LA 3ZUKA 3G5CA 2FV5A 4XCTA 4HMAA 4HX3A 4WKEA 3KWVC 2E2DA 2MZHA 3OHOA 3F18A 1QUAA 2K2GA 2CKIA 1XFVA 4QKZA 4PKWA 3UVCA 1G49A 1WNIA 3B2ZA 4A7BA 2FV9A 1PWUA 1XUDA 1PWPA 4JA1A 4ZR5A 4XM8A 3O64A 3DL1A 2HU6A 1BZSA 3HBVP 4FXYP 1R54A 3U1RA 3LUNA 2XS4A 3O2XA 4G9LA 2SRTA 1SLNA 2RJPA 1K7GA 1JKYA 5CZMA 5D1TA 1GKCA 3LILA 5BOTA 3LJZA 3N2VA 2OW2A 3LMCA 1OM6A 1IACA 2I47A 2OVXA 1UTZA 3KRYA 1CQRA 4H1QA 5D7WA 3LIKA 4L63A 2W15A 1ZXVA 2YIGA 1QIBA 1D8MA 1CGEA 1G05A 3DPFA 1ZP5A 3B8ZA 3L0TA 1Y0VA 1FLSA 3USNA 4FXQA 2JIHA 3N2UA 3LIRA 3E8RA 1UTTA 3LUMA 4H49A 2MLRA 3HY9A 1CXVA 3DNGA 1CGFA 1G4KA 3CKIA 1XFXA 3HY7A 2OXWA 4I03A 1H71P 1MMBA 2JSDA 2DW1A 1QJIA 2W0DA 1R55A 1SMPA 3LEAA 1BKCE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VTG A;  3L0V A;  2OXU A;  1Y93 A;  1BIW A;  1OS2 A;  5B5O A;  4DF9 A;  2MZE A;  2AIG P;  2Y6C A;  3TSK A;  5BOY A;  2POJ A;  1R1H A;  3EHY A;  3HDB A;  1HTD A;  3I7G A;  4GR3 A;  3V96 B;  2OZR A;  3EDG A;  1HY7 A;  1BQO A;  2WOA A;  1IAD A;  3HYG A;  4JP4 A;  3Q2G A;  4IJO A;  2A8H A;  5L79 A;  1QIC A;  4FU4 A;  1GE7 A;  1PWV A;  4PKR A;  2JT6 A;  1A85 A;  1YQY A;  1JJ9 A;  3P1V A;  1JAP A;  3LGP A;  1CIZ A;  4GWN A;  3ZXH A;  1OMJ A;  3EDH A;  2X3B A;  1CK7 A;  1MNC A;  1C3I A;  1QIA A;  4H76 A;  1MMR A;  2TCL A;  1S4B P;  1O0Q A;  3MA2 A;  3ZVS A;  5D1S A;  2CLT A;  1OM8 A;  5H8X A;  3F16 A;  4G0D A;  4WF6 A;  1K7I A;  1JK3 A;  3SHI A;  2XS3 A;  3Q2H A;  2DDF A;  2OY2 A;  1YOU A;  1BSW A;  2OY4 A;  4FVL A;  2DDY A;  2OW1 A;  1FBL A;  4GQL A;  2OI0 A;  4L19 A;  1GE5 A;  4AYK A;  1BUV M;  3I7I A;  3ELM A;  2X7M A;  1Q3A A;  3LQB A;  5I2Z A;  1KUG A;  3EDI A;  4R3V A;  2RJQ A;  4H84 A;  1MMQ A;  3AYU A;  3WV3 A;  1DTH A;  1ATL A;  3GBO A;  3BA0 A;  4DV8 A;  1KUH A;  4IUW A;  1CAQ A;  1BQQ M;  2N8R A;  1IAB A;  4JQG A;  4H3X A;  4GUY A;  1AYK A;  4GR8 A;  4GF1 A;  3TT4 A;  3KME A;  4PKV A;  2YB9 A;  1ZVX A;  5D1U A;  5LAB A;  1SAT A;  1FM1 A;  4H2E A;  1USN A;  2DW0 A;  4J4M A;  5D2B A;  4IN9 A;  1JH1 A;  1XFU A;  1I73 A;  3AYK A;  1AKL A;  1GE6 A;  1PWW A;  3DPE A;  2MLS A;  2OVZ A;  1BUD A;  1GO8 P;  2X3A A;  1QJJ A;  1ZS0 A;  1JIW P;  1KBC A;  3RTT A;  4A3W A;  2OW0 A;  3WV2 A;  1XFW A;  4DD8 A;  3EDZ A;  4PKQ A;  1JAQ A;  2J0T A;  1ND1 A;  2O36 A;  1CGL A;  4DPE A;  1I1I P;  3P24 A;  2ERO A;  2PJT A;  3F17 A;  1L6J A;  1OM7 A;  1D8F A;  1B8Y A;  1GKD A;  2L0R A;  3RTS A;  1HFC A;  4WZV A;  3F1A A;  3LE9 A;  4ILW D;  1EB6 A;  1A86 A;  1R1I A;  1RMZ A;  1ZXC A;  2J83 A;  4XBH A;  1JIZ A;  1ZTQ A;  3KEK A;  4ON1 A;  5I4O A;  966C A;  2D1N A;  1IAG A;  456C A;  5B5P A;  1AST A;  1BKC A;  2JNP A;  3F19 A;  1KUI A;  3OHL A;  1HOV A;  1EUB A;  1ROS A;  3LK8 A;  5CXA A;  1BKC I;  3LJG A;  2DW2 A;  1UMT A;  4AUO A;  1SU3 A;  2WO8 A;  2JT5 A;  1EAK A;  1J7N A;  4GWM A;  4WKI A;  2ERP A;  3KEJ A;  1XUR A;  1MMP A;  3DSL A;  3EWJ A;  5I3M A;  4Q1L A;  5L7F A;  1PWQ A;  4WK7 A;  3AIG A;  1JAO A;  1OO9 A;  2O3E A;  1IAE A;  3B92 A;  3K7N A;  1Z3J A;  4XM6 A;  3KHI A;  3F15 A;  4I35 A;  1DMT A;  2W14 A;  2ERQ A;  1SLM A;  1RM8 A;  4PKU A;  4PKS A;  5I0L A;  1K7Q A;  1KUK A;  1HV5 A;  2Y6D A;  5D3C A;  2Z2D A;  1BM6 A;  3TS4 A;  3TVC A;  4CTH A;  5JMY A;  1UEA A;  1AF0 A;  3G42 A;  1Y8J A;  5CUH A;  1G12 A;  1SRP A;  4GR0 A;  2OXZ A;  5BPA A;  830C A;  1R1J A;  2QPJ A;  4JPA A;  4PKT A;  1KAP P;  3HBU P;  2V4B A;  4H82 A;  1YP1 A;  2D1O A;  3LQ0 A;  4AIG A;  2W12 A;  1HFS A;  2USN A;  2OW9 A;  1GXD A;  5I43 A;  4EFS A;  1IAA A;  3DWB A;  3LKA A;  4JIJ A;  4L6T A;  5I12 A;  1OS9 A;  3HB2 P;  3LJT A;  1C7K A;  4XM7 A;  1D5J A;  3EHX A;  1GO7 P;  1XFZ A;  3KMC A;  1O0T A;  2K9C A;  2WO9 A;  1XFY A;  1C8T A;  1JAN A;  1B3D A;  2X3C A;  2KRJ A;  3NX7 A;  3VI1 A;  4H30 A;  1I76 A;  3KEC A;  1KUF A;  1UMS A;  2AYK A;  1YCM A;  2W13 A;  4AXQ A;  3HDA P;  1XUC A;  3WV1 A;  1D7X A;  1G9K A;  2E3X A;  2MZI A;  3K7L A;  3ZUK A;  3G5C A;  2FV5 A;  4XCT A;  4HMA A;  4HX3 A;  4WKE A;  3KWV C;  2E2D A;  2MZH A;  3OHO A;  3F18 A;  1QUA A;  2K2G A;  2CKI A;  1XFV A;  4QKZ A;  4PKW A;  3UVC A;  1G49 A;  1WNI A;  3B2Z A;  4A7B A;  2FV9 A;  1PWU A;  1XUD A;  1PWP A;  4JA1 A;  4ZR5 A;  4XM8 A;  3O64 A;  3DL1 A;  2HU6 A;  1BZS A;  3HBV P;  4FXY P;  1R54 A;  3U1R A;  3LUN A;  2XS4 A;  3O2X A;  4G9L A;  2SRT A;  1SLN A;  2RJP A;  1K7G A;  1JKY A;  5CZM A;  5D1T A;  1GKC A;  3LIL A;  5BOT A;  3LJZ A;  3N2V A;  2OW2 A;  3LMC A;  1OM6 A;  1IAC A;  2I47 A;  2OVX A;  1UTZ A;  3KRY A;  1CQR A;  4H1Q A;  5D7W A;  3LIK A;  4L63 A;  2W15 A;  1ZXV A;  2YIG A;  1QIB A;  1D8M A;  1CGE A;  1G05 A;  3DPF A;  1ZP5 A;  3B8Z A;  3L0T A;  1Y0V A;  1FLS A;  3USN A;  4FXQ A;  2JIH A;  3N2U A;  3LIR A;  3E8R A;  1UTT A;  3LUM A;  4H49 A;  2MLR A;  3HY9 A;  1CXV A;  3DNG A;  1CGF A;  1G4K A;  3CKI A;  1XFX A;  3HY7 A;  2OXW A;  4I03 A;  1H71 P;  1MMB A;  2JSD A;  2DW1 A;  1QJI A;  2W0D A;  1R55 A;  1SMP A;  3LEA A;  1BKC E; 
#chains in the Genus database with same CATH topology
 3VTG A;  3L0V A;  2OXU A;  1Y93 A;  1BIW A;  1OS2 A;  5B5O A;  4DF9 A;  2MZE A;  2AIG P;  2Y6C A;  3TSK A;  5BOY A;  2POJ A;  1R1H A;  3EHY A;  3HDB A;  1HTD A;  3I7G A;  4GR3 A;  3V96 B;  2OZR A;  1XM5 A;  3EDG A;  1HY7 A;  1BQO A;  2WOA A;  1IAD A;  3HYG A;  4JP4 A;  3Q2G A;  4IJO A;  2A8H A;  5L79 A;  1QIC A;  4FU4 A;  1GE7 A;  1PWV A;  4PKR A;  2JT6 A;  1A85 A;  1YQY A;  1JJ9 A;  3P1V A;  1JAP A;  3LGP A;  1CIZ A;  4GWN A;  3ZXH A;  1OMJ A;  3EDH A;  2X3B A;  1CK7 A;  1MNC A;  1C3I A;  1QIA A;  4H76 A;  1MMR A;  2TCL A;  1S4B P;  1O0Q A;  3MA2 A;  3ZVS A;  5D1S A;  2CLT A;  1OM8 A;  5H8X A;  3F16 A;  4G0D A;  4WF6 A;  1K7I A;  1JK3 A;  3SHI A;  2XS3 A;  3Q2H A;  2DDF A;  2OY2 A;  1YOU A;  1BSW A;  2OY4 A;  4FVL A;  2DDY A;  2OW1 A;  1FBL A;  4GQL A;  2OI0 A;  4L19 A;  1GE5 A;  4AYK A;  1BUV M;  3I7I A;  3ELM A;  2X7M A;  1Q3A A;  3LQB A;  5I2Z A;  1KUG A;  3EDI A;  4R3V A;  2RJQ A;  4H84 A;  1MMQ A;  3AYU A;  3WV3 A;  1DTH A;  1ATL A;  3GBO A;  3BA0 A;  4DV8 A;  1KUH A;  4IUW A;  1CAQ A;  1BQQ M;  2N8R A;  1IAB A;  4JQG A;  4H3X A;  4GUY A;  1AYK A;  4GR8 A;  4GF1 A;  3TT4 A;  3KME A;  4PKV A;  2YB9 A;  1ZVX A;  5D1U A;  5LAB A;  1SAT A;  1FM1 A;  4H2E A;  1USN A;  2DW0 A;  4J4M A;  5D2B A;  2YUF A;  4IN9 A;  1JH1 A;  1XFU A;  1I73 A;  3AYK A;  1AKL A;  1GE6 A;  1PWW A;  3DPE A;  2MLS A;  2OVZ A;  1BUD A;  1GO8 P;  2X3A A;  1QJJ A;  1ZS0 A;  1JIW P;  1KBC A;  3RTT A;  3DTI A;  4A3W A;  2OW0 A;  3WV2 A;  1XFW A;  4DD8 A;  3EDZ A;  4PKQ A;  1JAQ A;  2J0T A;  1ND1 A;  2O36 A;  1CGL A;  4DPE A;  1TVI A;  3DTE A;  1I1I P;  1XAX A;  3P24 A;  2ERO A;  2PJT A;  3F17 A;  1L6J A;  1OM7 A;  1D8F A;  1B8Y A;  1GKD A;  2L0R A;  3RTS A;  1HFC A;  4WZV A;  4L7A A;  3F1A A;  3LE9 A;  4ILW D;  1EB6 A;  1A86 A;  1R1I A;  1RMZ A;  1ZXC A;  2J83 A;  4XBH A;  1JIZ A;  1ZTQ A;  3KEK A;  4ON1 A;  5I4O A;  966C A;  2D1N A;  1IAG A;  456C A;  5B5P A;  1AST A;  1BKC A;  2JNP A;  3F19 A;  1KUI A;  3OHL A;  1HOV A;  1EUB A;  1ROS A;  3LK8 A;  5CXA A;  1BKC I;  3LJG A;  2DW2 A;  1UMT A;  4AUO A;  1SU3 A;  2WO8 A;  2JT5 A;  1EAK A;  3DTK A;  1J7N A;  4GWM A;  4WKI A;  2ERP A;  3KEJ A;  1XUR A;  1MMP A;  3DSL A;  3EWJ A;  5I3M A;  4Q1L A;  5L7F A;  1PWQ A;  4WK7 A;  3AIG A;  1JAO A;  1OO9 A;  2O3E A;  1IAE A;  3B92 A;  3K7N A;  1Z3J A;  4XM6 A;  3KHI A;  3F15 A;  4I35 A;  1DMT A;  2W14 A;  2ERQ A;  1SLM A;  1RM8 A;  4PKU A;  4PKS A;  5I0L A;  1K7Q A;  1KUK A;  1HV5 A;  2Y6D A;  5D3C A;  2Z2D A;  1BM6 A;  3TS4 A;  3TVC A;  4CTH A;  5JMY A;  1UEA A;  1AF0 A;  3G42 A;  1Y8J A;  5CUH A;  1G12 A;  1SRP A;  4GR0 A;  2OXZ A;  5BPA A;  830C A;  1R1J A;  2QPJ A;  4JPA A;  4PKT A;  1KAP P;  3HBU P;  2V4B A;  4H82 A;  1YP1 A;  2D1O A;  3LQ0 A;  4AIG A;  2W12 A;  1HFS A;  2USN A;  2OW9 A;  1GXD A;  5I43 A;  4EFS A;  1IAA A;  3DWB A;  3LKA A;  4JIJ A;  4L6T A;  5I12 A;  1OS9 A;  3HB2 P;  3LJT A;  1C7K A;  4XM7 A;  1D5J A;  3EHX A;  1GO7 P;  1OZ9 A;  1XFZ A;  3KMC A;  1O0T A;  2K9C A;  2WO9 A;  1XFY A;  1C8T A;  1JAN A;  1B3D A;  2X3C A;  2KRJ A;  3NX7 A;  3VI1 A;  4H30 A;  1I76 A;  3KEC A;  1KUF A;  1UMS A;  2AYK A;  1YCM A;  2W13 A;  4AXQ A;  3HDA P;  1XUC A;  3WV1 A;  1D7X A;  1G9K A;  2E3X A;  2MZI A;  3K7L A;  3ZUK A;  3G5C A;  2FV5 A;  4XCT A;  4HMA A;  4HX3 A;  4WKE A;  3KWV C;  2E2D A;  2MZH A;  3OHO A;  3F18 A;  1QUA A;  2K2G A;  2CKI A;  1XFV A;  4QKZ A;  4PKW A;  3UVC A;  1G49 A;  1WNI A;  3B2Z A;  4A7B A;  2FV9 A;  1PWU A;  1XUD A;  1PWP A;  4JA1 A;  4ZR5 A;  4XM8 A;  3O64 A;  3DL1 A;  2HU6 A;  1BZS A;  3HBV P;  4FXY P;  1R54 A;  3U1R A;  3LUN A;  2XS4 A;  3O2X A;  4G9L A;  2SRT A;  1SLN A;  2RJP A;  1K7G A;  1JKY A;  5CZM A;  5D1T A;  1GKC A;  3LIL A;  5BOT A;  3LJZ A;  3N2V A;  2OW2 A;  3LMC A;  1OM6 A;  1IAC A;  2I47 A;  2OVX A;  1UTZ A;  3KRY A;  1CQR A;  4H1Q A;  5D7W A;  3LIK A;  4L63 A;  2W15 A;  1ZXV A;  2YIG A;  1QIB A;  1D8M A;  1CGE A;  1G05 A;  3DPF A;  1ZP5 A;  3B8Z A;  3L0T A;  1Y0V A;  1FLS A;  3USN A;  4FXQ A;  2JIH A;  3N2U A;  3LIR A;  3E8R A;  1UTT A;  3LUM A;  4H49 A;  2MLR A;  3HY9 A;  1CXV A;  3DNG A;  1CGF A;  1G4K A;  3CKI A;  1XFX A;  3HY7 A;  2OXW A;  4I03 A;  1H71 P;  1MMB A;  2JSD A;  2DW1 A;  1QJI A;  2W0D A;  1R55 A;  1SMP A;  3LEA A;  1BKC E; 
#chains in the Genus database with same CATH homology
 3VTG A;  3L0V A;  2OXU A;  1Y93 A;  1BIW A;  1OS2 A;  5B5O A;  4DF9 A;  2MZE A;  2AIG P;  2Y6C A;  3TSK A;  5BOY A;  2POJ A;  1R1H A;  3EHY A;  3HDB A;  1HTD A;  3I7G A;  4GR3 A;  3V96 B;  2OZR A;  3EDG A;  1HY7 A;  1BQO A;  2WOA A;  1IAD A;  3HYG A;  4JP4 A;  3Q2G A;  4IJO A;  2A8H A;  5L79 A;  1QIC A;  4FU4 A;  1GE7 A;  1PWV A;  4PKR A;  2JT6 A;  1A85 A;  1YQY A;  1JJ9 A;  3P1V A;  1JAP A;  3LGP A;  1CIZ A;  4GWN A;  3ZXH A;  1OMJ A;  3EDH A;  2X3B A;  1CK7 A;  1MNC A;  1C3I A;  1QIA A;  4H76 A;  1MMR A;  2TCL A;  1S4B P;  1O0Q A;  3MA2 A;  3ZVS A;  5D1S A;  2CLT A;  1OM8 A;  5H8X A;  3F16 A;  4G0D A;  4WF6 A;  1K7I A;  1JK3 A;  3SHI A;  2XS3 A;  3Q2H A;  2DDF A;  2OY2 A;  1YOU A;  1BSW A;  2OY4 A;  4FVL A;  2DDY A;  2OW1 A;  1FBL A;  4GQL A;  2OI0 A;  4L19 A;  1GE5 A;  4AYK A;  1BUV M;  3I7I A;  3ELM A;  2X7M A;  1Q3A A;  3LQB A;  5I2Z A;  1KUG A;  3EDI A;  4R3V A;  2RJQ A;  4H84 A;  1MMQ A;  3AYU A;  3WV3 A;  1DTH A;  1ATL A;  3GBO A;  3BA0 A;  4DV8 A;  1KUH A;  4IUW A;  1CAQ A;  1BQQ M;  2N8R A;  1IAB A;  4JQG A;  4H3X A;  4GUY A;  1AYK A;  4GR8 A;  4GF1 A;  3TT4 A;  3KME A;  4PKV A;  2YB9 A;  1ZVX A;  5D1U A;  5LAB A;  1SAT A;  1FM1 A;  4H2E A;  1USN A;  2DW0 A;  4J4M A;  5D2B A;  2YUF A;  4IN9 A;  1JH1 A;  1XFU A;  1I73 A;  3AYK A;  1AKL A;  1GE6 A;  1PWW A;  3DPE A;  2MLS A;  2OVZ A;  1BUD A;  1GO8 P;  2X3A A;  1QJJ A;  1ZS0 A;  1JIW P;  1KBC A;  3RTT A;  3DTI A;  4A3W A;  2OW0 A;  3WV2 A;  1XFW A;  4DD8 A;  3EDZ A;  4PKQ A;  1JAQ A;  2J0T A;  1ND1 A;  2O36 A;  1CGL A;  4DPE A;  3DTE A;  1I1I P;  3P24 A;  2ERO A;  2PJT A;  3F17 A;  1L6J A;  1OM7 A;  1D8F A;  1B8Y A;  1GKD A;  2L0R A;  3RTS A;  1HFC A;  4WZV A;  4L7A A;  3F1A A;  3LE9 A;  4ILW D;  1EB6 A;  1A86 A;  1R1I A;  1RMZ A;  1ZXC A;  2J83 A;  4XBH A;  1JIZ A;  1ZTQ A;  3KEK A;  4ON1 A;  5I4O A;  966C A;  2D1N A;  1IAG A;  456C A;  5B5P A;  1AST A;  1BKC A;  2JNP A;  3F19 A;  1KUI A;  3OHL A;  1HOV A;  1EUB A;  1ROS A;  3LK8 A;  5CXA A;  1BKC I;  3LJG A;  2DW2 A;  1UMT A;  4AUO A;  1SU3 A;  2WO8 A;  2JT5 A;  1EAK A;  3DTK A;  1J7N A;  4GWM A;  4WKI A;  2ERP A;  3KEJ A;  1XUR A;  1MMP A;  3DSL A;  3EWJ A;  5I3M A;  4Q1L A;  5L7F A;  1PWQ A;  4WK7 A;  3AIG A;  1JAO A;  1OO9 A;  2O3E A;  1IAE A;  3B92 A;  3K7N A;  1Z3J A;  4XM6 A;  3KHI A;  3F15 A;  4I35 A;  1DMT A;  2W14 A;  2ERQ A;  1SLM A;  1RM8 A;  4PKU A;  4PKS A;  5I0L A;  1K7Q A;  1KUK A;  1HV5 A;  2Y6D A;  5D3C A;  2Z2D A;  1BM6 A;  3TS4 A;  3TVC A;  4CTH A;  5JMY A;  1UEA A;  1AF0 A;  3G42 A;  1Y8J A;  5CUH A;  1G12 A;  1SRP A;  4GR0 A;  2OXZ A;  5BPA A;  830C A;  1R1J A;  2QPJ A;  4JPA A;  4PKT A;  1KAP P;  3HBU P;  2V4B A;  4H82 A;  1YP1 A;  2D1O A;  3LQ0 A;  4AIG A;  2W12 A;  1HFS A;  2USN A;  2OW9 A;  1GXD A;  5I43 A;  4EFS A;  1IAA A;  3DWB A;  3LKA A;  4JIJ A;  4L6T A;  5I12 A;  1OS9 A;  3HB2 P;  3LJT A;  1C7K A;  4XM7 A;  1D5J A;  3EHX A;  1GO7 P;  1XFZ A;  3KMC A;  1O0T A;  2K9C A;  2WO9 A;  1XFY A;  1C8T A;  1JAN A;  1B3D A;  2X3C A;  2KRJ A;  3NX7 A;  3VI1 A;  4H30 A;  1I76 A;  3KEC A;  1KUF A;  1UMS A;  2AYK A;  1YCM A;  2W13 A;  4AXQ A;  3HDA P;  1XUC A;  3WV1 A;  1D7X A;  1G9K A;  2E3X A;  2MZI A;  3K7L A;  3ZUK A;  3G5C A;  2FV5 A;  4XCT A;  4HMA A;  4HX3 A;  4WKE A;  3KWV C;  2E2D A;  2MZH A;  3OHO A;  3F18 A;  1QUA A;  2K2G A;  2CKI A;  1XFV A;  4QKZ A;  4PKW A;  3UVC A;  1G49 A;  1WNI A;  3B2Z A;  4A7B A;  2FV9 A;  1PWU A;  1XUD A;  1PWP A;  4JA1 A;  4ZR5 A;  4XM8 A;  3O64 A;  3DL1 A;  2HU6 A;  1BZS A;  3HBV P;  4FXY P;  1R54 A;  3U1R A;  3LUN A;  2XS4 A;  3O2X A;  4G9L A;  2SRT A;  1SLN A;  2RJP A;  1K7G A;  1JKY A;  5CZM A;  5D1T A;  1GKC A;  3LIL A;  5BOT A;  3LJZ A;  3N2V A;  2OW2 A;  3LMC A;  1OM6 A;  1IAC A;  2I47 A;  2OVX A;  1UTZ A;  3KRY A;  1CQR A;  4H1Q A;  5D7W A;  3LIK A;  4L63 A;  2W15 A;  1ZXV A;  2YIG A;  1QIB A;  1D8M A;  1CGE A;  1G05 A;  3DPF A;  1ZP5 A;  3B8Z A;  3L0T A;  1Y0V A;  1FLS A;  3USN A;  4FXQ A;  2JIH A;  3N2U A;  3LIR A;  3E8R A;  1UTT A;  3LUM A;  4H49 A;  2MLR A;  3HY9 A;  1CXV A;  3DNG A;  1CGF A;  1G4K A;  3CKI A;  1XFX A;  3HY7 A;  2OXW A;  4I03 A;  1H71 P;  1MMB A;  2JSD A;  2DW1 A;  1QJI A;  2W0D A;  1R55 A;  1SMP A;  3LEA A;  1BKC E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...