5I4OA

Crystal structure of the catalytic domain of mmp-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (dc28).
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
156
structure length
156
Chain Sequence
VWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHQIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Macrophage metalloelastase
total genus 50
structure length 156
sequence length 156
chains with identical sequence B, C, D
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2016-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 5i4oA00
1ATLA 2DW2A 3LILA 1C8TA 456CA 4JQGA 2J83A 4PKSA 1K7GA 1D8MA 1G9KA 1HFCA 1D5JA 1JIZA 1YQYA 1GE7A 1B8YA 1R1JA 1HY7A 3LQBA 4JPAA 1XFYA 5BPAA 1AKLA 1CGEA 1PWPA 4GQLA 1BSWA 1USNA 3HYGA 5D2BA 2EROA 3LE9A 1R1IA 4G0DA 3NX7A 3ZXHA 2OW1A 1KAPP 3AYUA 2CKIA 1OM8A 1YP1A 4A3WA 1Y0VA 2K2GA 1B3DA 4XM7A 2W12A 2W13A 4DF9A 5I12A 3Q2HA 1ZVXA 2X3CA 1GKCA 1ZP5A 1OO9A 1ZXVA 3B92A 4XM8A 1QIAA 966CA 2WO8A 1BQOA 2W14A 2ERQA 1SLMA 1MMRA 4ON1A 1OS2A 1GO8P 1PWUA 4EFSA 1RMZA 3EDZA 4GWNA 3USNA 2KRJA 2OZRA 4L6TA 3P24A 1OMJA 2JT6A 4H82A 5BOYA 1XURA 1IAAA 5CZMA 5D3CA 3KEJA 2OW2A 2E3XA 4HX3A 4I35A 1IADA 1QICA 2E2DA 5I2ZA 4GF1A 4GWMA 4H2EA 1KUIA 3I7GA 3F17A 4FVLA 3KMCA 3EWJA 1G49A 1ROSA 1MMBA 3P1VA 1L6JA 2OI0A 5H8XA 3K7LA 3KRYA 4J4MA 2OW0A 1K7QA 3DPFA 4FU4A 1G4KA 1ASTA 4ILWD 1BM6A 1MMQA 1UEAA 3DWBA 1QUAA 2TCLA 3DSLA 1KUKA 4AXQA 3N2VA 4G9LA 1XUDA 1UMSA 1JH1A 5CXAA 3LJGA 2YIGA 1DMTA 2DW1A 1UTTA 4GR8A 4IJOA 2D1NA 2WOAA 1PWQA 3LMCA 2OY4A 1AF0A 2HU6A 1XFXA 2POJA 1KUHA 3LUMA 1AYKA 2L0RA 2FV9A 5D1TA 2MZHA 2JT5A 3SHIA 2W15A 3LIRA 5I3MA 3KWVC 3F18A 1PWWA 2OXUA 2Y6CA 4Q1LA 1EB6A 2OVZA 4JP4A 1BUDA 1QJIA 2W0DA 2YB9A 3TVCA 1K7IA 1GXDA 3KEKA 3KHIA 4AYKA 3LJTA 1CXVA 1CK7A 5B5PA 1BKCE 4IN9A 3V96B 1JJ9A 2X3AA 4WZVA 3TS4A 4I03A 2J0TA 3LKAA 1KBCA 5D7WA 3EHXA 3TT4A 1XFWA 2MZIA 3LIKA 3ZUKA 4PKRA 3LGPA 1FLSA 3DL1A 3AYKA 3EHYA 1C3IA 1SU3A 5JMYA 1G05A 1PWVA 4AIGA 2JIHA 3O2XA 1SLNA 2FV5A 4DD8A 1I76A 2V4BA 1G12A 2K9CA 4PKQA 2O3EA 1OM7A 4XCTA 3LQ0A 1A86A 1JAOA 2AYKA 3ELMA 1IACA 3GBOA 2X3BA 1ZXCA 1BIWA 2DDYA 5LABA 1MNCA 1H71P 3ZVSA 1Z3JA 1JANA 4WK7A 2RJPA 3HDAP 3KECA 2OXWA 2JNPA 2I47A 2OW9A 1D7XA 5I43A 1JAPA 1MMPA 3RTSA 3LUNA 3WV2A 1DTHA 2CLTA 2XS3A 3EDHA 3Q2GA 2N8RA 1ZS0A 1XFVA 2JSDA 1CIZA 3L0VA 4PKTA 4H49A 3G5CA 1D8FA 4JIJA 4IUWA 1BZSA 1YOUA 4FXQA 3AIGA 3OHLA 3WV1A 1JAQA 3F15A 2Y6DA 4WKIA 4GR3A 1RM8A 3O64A 1FBLA 1CGLA 1UTZA 1OM6A 1O0TA 3HBVP 1BUVM 2USNA 1HFSA 2DW0A 1GE5A 3F1AA 5BOTA 2PJTA 5L79A 4L63A 2QPJA 5L7FA 3UVCA 2D1OA 3LJZA 3VTGA 1S4BP 3OHOA 1EUBA 1IAEA 4GR0A 2AIGP 4HMAA 3F19A 5D1SA 3B8ZA 1HV5A 4ZR5A 4XM6A 1IAGA 1XFZA 4R3VA 1SATA 1QIBA 1JK3A 3HDBA 2A8HA 1O0QA 5I4OA 1R55A 2ERPA 4QKZA 4A7BA 3L0TA 2O36A 1JKYA 3K7NA 4PKVA 1JIWP 4JA1A 1ND1A 830CA 4H76A 4DPEA 3EDIA 1QJJA 4AUOA 3N2UA 5D1UA 3B2ZA 4H1QA 1FM1A 5I0LA 3TSKA 4PKWA 3I7IA 1I73A 2Z2DA 1A85A 1R1HA 3BA0A 1ZTQA 1OS9A 1Y93A 3HBUP 1YCMA 3HY9A 4GUYA 3EDGA 4H84A 1HTDA 4H3XA 3DNGA 3KMEA 3E8RA 4XBHA 2RJQA 1CQRA 1HOVA 2SRTA 3CKIA 1GKDA 4FXYP 1KUFA 3G42A 3RTTA 2OVXA 1BKCI 1Y8JA 1J7NA 1Q3AA 2OY2A 1SMPA 1GE6A 4DV8A 4WF6A 2X7MA 1CGFA 2DDFA 4WKEA 1UMTA 2MLSA 1KUGA 2WO9A 1BKCA 4CTHA 3U1RA 2OXZA 1BQQM 3LEAA 3HB2P 3DPEA 5B5OA 1XUCA 2XS4A 3LK8A 5CUHA 4H30A 3WV3A 2MLRA 1R54A 1WNIA 1GO7P 4L19A 4PKUA 1IABA 3MA2A 3HY7A 1C7KA 2MZEA 1CAQA 1I1IP 3VI1A 1XFUA 1SRPA 1EAKA 3F16A
chains in the Genus database with same CATH superfamily
1ATLA 2DW2A 3LILA 1C8TA 456CA 4JQGA 2J83A 4PKSA 1K7GA 1D8MA 1G9KA 1HFCA 1D5JA 1JIZA 1YQYA 1GE7A 1B8YA 1R1JA 1HY7A 3LQBA 4JPAA 1XFYA 5BPAA 1AKLA 1CGEA 1PWPA 4GQLA 1BSWA 1USNA 3HYGA 5D2BA 2EROA 3LE9A 1R1IA 4G0DA 3NX7A 3ZXHA 2OW1A 1KAPP 3AYUA 2CKIA 1OM8A 1YP1A 4A3WA 1Y0VA 2K2GA 1B3DA 4XM7A 2W12A 2W13A 4DF9A 5I12A 3Q2HA 1ZVXA 2X3CA 1GKCA 1ZP5A 1OO9A 1ZXVA 3B92A 4XM8A 1QIAA 966CA 2WO8A 1BQOA 2W14A 2ERQA 1SLMA 1MMRA 4ON1A 1OS2A 1GO8P 1PWUA 4EFSA 1RMZA 3DTKA 3EDZA 4GWNA 3USNA 2KRJA 2OZRA 4L6TA 3P24A 1OMJA 2JT6A 4H82A 5BOYA 1XURA 1IAAA 5CZMA 5D3CA 3KEJA 2OW2A 2E3XA 4HX3A 4I35A 1IADA 1QICA 2E2DA 5I2ZA 4GF1A 4GWMA 4H2EA 1KUIA 3I7GA 3F17A 4FVLA 3KMCA 3EWJA 1G49A 1ROSA 1MMBA 3P1VA 1L6JA 2OI0A 5H8XA 3K7LA 3KRYA 4J4MA 2OW0A 1K7QA 3DPFA 4FU4A 1G4KA 1ASTA 4ILWD 1BM6A 1MMQA 1UEAA 3DWBA 1QUAA 2TCLA 3DSLA 1KUKA 4AXQA 3N2VA 4G9LA 1XUDA 1UMSA 1JH1A 5CXAA 3LJGA 2YIGA 1DMTA 2DW1A 1OZ9A 1UTTA 4GR8A 4IJOA 2D1NA 2WOAA 1PWQA 3LMCA 2OY4A 1AF0A 2HU6A 1XFXA 2POJA 1KUHA 3LUMA 1AYKA 2L0RA 2FV9A 5D1TA 2MZHA 2JT5A 3SHIA 2W15A 3LIRA 5I3MA 3KWVC 3F18A 1PWWA 2OXUA 2Y6CA 4Q1LA 1EB6A 2OVZA 4JP4A 1BUDA 1QJIA 2W0DA 2YB9A 3TVCA 1K7IA 1GXDA 3KEKA 3KHIA 4AYKA 3LJTA 1CXVA 1CK7A 5B5PA 1BKCE 4IN9A 3V96B 1JJ9A 2X3AA 4WZVA 3TS4A 4I03A 2J0TA 3LKAA 1KBCA 4L7AA 5D7WA 3EHXA 3TT4A 1XFWA 2MZIA 3LIKA 3ZUKA 4PKRA 3LGPA 1FLSA 3DL1A 3AYKA 3EHYA 1C3IA 1SU3A 5JMYA 1XM5A 1G05A 1PWVA 4AIGA 2JIHA 3O2XA 1SLNA 2FV5A 4DD8A 1I76A 2V4BA 1G12A 2K9CA 4PKQA 2O3EA 1OM7A 4XCTA 3LQ0A 1A86A 1JAOA 2AYKA 3ELMA 1IACA 3GBOA 3DTEA 2X3BA 1ZXCA 1BIWA 2DDYA 5LABA 1MNCA 1H71P 3ZVSA 1Z3JA 1JANA 4WK7A 2RJPA 3HDAP 3KECA 2OXWA 2JNPA 2I47A 2OW9A 1D7XA 5I43A 1JAPA 1MMPA 3RTSA 3LUNA 3WV2A 1DTHA 2CLTA 2XS3A 3EDHA 3Q2GA 2N8RA 1TVIA 1ZS0A 1XFVA 2JSDA 1CIZA 3L0VA 4PKTA 4H49A 3G5CA 1D8FA 4JIJA 4IUWA 1BZSA 1YOUA 4FXQA 3AIGA 3OHLA 3WV1A 1JAQA 3F15A 2Y6DA 4WKIA 4GR3A 1RM8A 3O64A 1FBLA 1XAXA 1CGLA 1UTZA 1OM6A 1O0TA 3HBVP 1BUVM 2USNA 1HFSA 2DW0A 1GE5A 3F1AA 5BOTA 2PJTA 5L79A 4L63A 2QPJA 5L7FA 3UVCA 2D1OA 3LJZA 3VTGA 1S4BP 3OHOA 1EUBA 1IAEA 4GR0A 2AIGP 4HMAA 3F19A 5D1SA 3B8ZA 1HV5A 4ZR5A 4XM6A 1IAGA 1XFZA 4R3VA 1SATA 1QIBA 1JK3A 3HDBA 2A8HA 1O0QA 5I4OA 1R55A 2ERPA 4QKZA 4A7BA 3L0TA 2O36A 1JKYA 3K7NA 4PKVA 1JIWP 4JA1A 1ND1A 830CA 4H76A 4DPEA 3EDIA 1QJJA 4AUOA 3N2UA 5D1UA 3B2ZA 4H1QA 1FM1A 5I0LA 3TSKA 4PKWA 3I7IA 1I73A 2Z2DA 1A85A 1R1HA 3BA0A 2YUFA 1ZTQA 1OS9A 3HY9A 1Y93A 1YCMA 3HBUP 4GUYA 3EDGA 4H84A 1HTDA 4H3XA 3DNGA 3KMEA 3E8RA 4XBHA 2RJQA 1CQRA 1HOVA 2SRTA 3CKIA 1GKDA 4FXYP 1KUFA 3G42A 3RTTA 2OVXA 1BKCI 1Y8JA 1J7NA 1Q3AA 2OY2A 1SMPA 1GE6A 4DV8A 4WF6A 2X7MA 1CGFA 2DDFA 4WKEA 1UMTA 2MLSA 1KUGA 2WO9A 1BKCA 4CTHA 3U1RA 2OXZA 1BQQM 3LEAA 3HB2P 3DPEA 5B5OA 1XUCA 2XS4A 3LK8A 5CUHA 4H30A 3WV3A 2MLRA 1R54A 1WNIA 1GO7P 4L19A 4PKUA 1IABA 3MA2A 3HY7A 3DTIA 1C7KA 2MZEA 1CAQA 1I1IP 3VI1A 1XFUA 1SRPA 1EAKA 3F16A
chains in the Genus database with same CATH topology
1ATLA 2DW2A 3LILA 1C8TA 456CA 4JQGA 2J83A 4PKSA 1K7GA 1D8MA 1G9KA 1HFCA 1D5JA 1JIZA 1YQYA 1GE7A 1B8YA 1R1JA 1HY7A 3LQBA 4JPAA 1XFYA 5BPAA 1AKLA 1CGEA 1PWPA 4GQLA 1BSWA 1USNA 3HYGA 5D2BA 2EROA 3LE9A 1R1IA 4G0DA 3NX7A 3ZXHA 2OW1A 1KAPP 3AYUA 2CKIA 1OM8A 1YP1A 4A3WA 1Y0VA 2K2GA 1B3DA 4XM7A 2W12A 2W13A 4DF9A 5I12A 3Q2HA 1ZVXA 2X3CA 1GKCA 1ZP5A 1OO9A 1ZXVA 3B92A 4XM8A 1QIAA 966CA 2WO8A 1BQOA 2W14A 2ERQA 1SLMA 1MMRA 4ON1A 1OS2A 1GO8P 1PWUA 4EFSA 1RMZA 3DTKA 3EDZA 4GWNA 3USNA 2KRJA 2OZRA 4L6TA 3P24A 1OMJA 2JT6A 4H82A 5BOYA 1XURA 1IAAA 5CZMA 5D3CA 3KEJA 2OW2A 2E3XA 4HX3A 4I35A 1IADA 1QICA 2E2DA 5I2ZA 4GF1A 4GWMA 4H2EA 1KUIA 3I7GA 3F17A 4FVLA 3KMCA 3EWJA 1G49A 1ROSA 1MMBA 3P1VA 1L6JA 2OI0A 5H8XA 3K7LA 3KRYA 4J4MA 2OW0A 1K7QA 3DPFA 4FU4A 1G4KA 1ASTA 4ILWD 1BM6A 1MMQA 1UEAA 3DWBA 1QUAA 2TCLA 3DSLA 1KUKA 4AXQA 3N2VA 4G9LA 1XUDA 1UMSA 1JH1A 5CXAA 3LJGA 2YIGA 1DMTA 2DW1A 1UTTA 4GR8A 4IJOA 2D1NA 2WOAA 1PWQA 3LMCA 2OY4A 1AF0A 2HU6A 1XFXA 2POJA 1KUHA 3LUMA 1AYKA 2L0RA 2FV9A 5D1TA 2MZHA 2JT5A 3SHIA 2W15A 3LIRA 5I3MA 3KWVC 3F18A 1PWWA 2OXUA 2Y6CA 4Q1LA 1EB6A 2OVZA 4JP4A 1BUDA 1QJIA 2W0DA 2YB9A 3TVCA 1K7IA 1GXDA 3KEKA 3KHIA 4AYKA 3LJTA 1CXVA 1CK7A 5B5PA 1BKCE 4IN9A 3V96B 1JJ9A 2X3AA 4WZVA 3TS4A 4I03A 2J0TA 3LKAA 1KBCA 4L7AA 5D7WA 3EHXA 3TT4A 1XFWA 2MZIA 3LIKA 3ZUKA 4PKRA 3LGPA 1FLSA 3DL1A 3AYKA 3EHYA 1C3IA 1SU3A 5JMYA 1G05A 1PWVA 4AIGA 2JIHA 3O2XA 1SLNA 2FV5A 4DD8A 1I76A 2V4BA 1G12A 2K9CA 4PKQA 2O3EA 1OM7A 4XCTA 3LQ0A 1A86A 1JAOA 2AYKA 3ELMA 1IACA 3GBOA 3DTEA 2X3BA 1ZXCA 1BIWA 2DDYA 5LABA 1MNCA 1H71P 3ZVSA 1Z3JA 1JANA 4WK7A 2RJPA 3HDAP 3KECA 2OXWA 2JNPA 2I47A 2OW9A 1D7XA 5I43A 1JAPA 1MMPA 3RTSA 3LUNA 3WV2A 1DTHA 2CLTA 2XS3A 3EDHA 3Q2GA 2N8RA 1ZS0A 1XFVA 2JSDA 1CIZA 3L0VA 4PKTA 4H49A 3G5CA 1D8FA 4JIJA 4IUWA 1BZSA 1YOUA 4FXQA 3AIGA 3OHLA 3WV1A 1JAQA 3F15A 2Y6DA 4WKIA 4GR3A 1RM8A 3O64A 1FBLA 1CGLA 1UTZA 1OM6A 1O0TA 3HBVP 1BUVM 2USNA 1HFSA 2DW0A 1GE5A 3F1AA 5BOTA 2PJTA 5L79A 4L63A 2QPJA 5L7FA 3UVCA 2D1OA 3LJZA 3VTGA 1S4BP 3OHOA 1EUBA 1IAEA 4GR0A 2AIGP 4HMAA 3F19A 5D1SA 3B8ZA 1HV5A 4ZR5A 4XM6A 1IAGA 1XFZA 4R3VA 1SATA 1QIBA 1JK3A 3HDBA 2A8HA 1O0QA 5I4OA 1R55A 2ERPA 4QKZA 4A7BA 3L0TA 2O36A 1JKYA 3K7NA 4PKVA 1JIWP 4JA1A 1ND1A 830CA 4H76A 4DPEA 3EDIA 1QJJA 4AUOA 3N2UA 5D1UA 3B2ZA 4H1QA 1FM1A 5I0LA 3TSKA 4PKWA 3I7IA 1I73A 2Z2DA 1A85A 1R1HA 3BA0A 2YUFA 1ZTQA 1OS9A 1Y93A 3HBUP 1YCMA 3HY9A 4GUYA 3EDGA 4H84A 1HTDA 4H3XA 3DNGA 3KMEA 3E8RA 4XBHA 2RJQA 1CQRA 1HOVA 2SRTA 3CKIA 1GKDA 4FXYP 1KUFA 3G42A 3RTTA 2OVXA 1BKCI 1Y8JA 1J7NA 1Q3AA 2OY2A 1SMPA 1GE6A 4DV8A 4WF6A 2X7MA 1CGFA 2DDFA 4WKEA 1UMTA 2MLSA 1KUGA 2WO9A 1BKCA 4CTHA 3U1RA 2OXZA 1BQQM 3LEAA 3HB2P 3DPEA 5B5OA 1XUCA 2XS4A 3LK8A 5CUHA 4H30A 3WV3A 2MLRA 1R54A 1WNIA 1GO7P 4L19A 4PKUA 1IABA 3MA2A 3HY7A 3DTIA 1C7KA 2MZEA 1CAQA 1I1IP 3VI1A 1XFUA 1SRPA 1EAKA 3F16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ATL A;  2DW2 A;  3LIL A;  1C8T A;  456C A;  4JQG A;  2J83 A;  4PKS A;  1K7G A;  1D8M A;  1G9K A;  1HFC A;  1D5J A;  1JIZ A;  1YQY A;  1GE7 A;  1B8Y A;  1R1J A;  1HY7 A;  3LQB A;  4JPA A;  1XFY A;  5BPA A;  1AKL A;  1CGE A;  1PWP A;  4GQL A;  1BSW A;  1USN A;  3HYG A;  5D2B A;  2ERO A;  3LE9 A;  1R1I A;  4G0D A;  3NX7 A;  3ZXH A;  2OW1 A;  1KAP P;  3AYU A;  2CKI A;  1OM8 A;  1YP1 A;  4A3W A;  1Y0V A;  2K2G A;  1B3D A;  4XM7 A;  2W12 A;  2W13 A;  4DF9 A;  5I12 A;  3Q2H A;  1ZVX A;  2X3C A;  1GKC A;  1ZP5 A;  1OO9 A;  1ZXV A;  3B92 A;  4XM8 A;  1QIA A;  966C A;  2WO8 A;  1BQO A;  2W14 A;  2ERQ A;  1SLM A;  1MMR A;  4ON1 A;  1OS2 A;  1GO8 P;  1PWU A;  4EFS A;  1RMZ A;  3EDZ A;  4GWN A;  3USN A;  2KRJ A;  2OZR A;  4L6T A;  3P24 A;  1OMJ A;  2JT6 A;  4H82 A;  5BOY A;  1XUR A;  1IAA A;  5CZM A;  5D3C A;  3KEJ A;  2OW2 A;  2E3X A;  4HX3 A;  4I35 A;  1IAD A;  1QIC A;  2E2D A;  5I2Z A;  4GF1 A;  4GWM A;  4H2E A;  1KUI A;  3I7G A;  3F17 A;  4FVL A;  3KMC A;  3EWJ A;  1G49 A;  1ROS A;  1MMB A;  3P1V A;  1L6J A;  2OI0 A;  5H8X A;  3K7L A;  3KRY A;  4J4M A;  2OW0 A;  1K7Q A;  3DPF A;  4FU4 A;  1G4K A;  1AST A;  4ILW D;  1BM6 A;  1MMQ A;  1UEA A;  3DWB A;  1QUA A;  2TCL A;  3DSL A;  1KUK A;  4AXQ A;  3N2V A;  4G9L A;  1XUD A;  1UMS A;  1JH1 A;  5CXA A;  3LJG A;  2YIG A;  1DMT A;  2DW1 A;  1UTT A;  4GR8 A;  4IJO A;  2D1N A;  2WOA A;  1PWQ A;  3LMC A;  2OY4 A;  1AF0 A;  2HU6 A;  1XFX A;  2POJ A;  1KUH A;  3LUM A;  1AYK A;  2L0R A;  2FV9 A;  5D1T A;  2MZH A;  2JT5 A;  3SHI A;  2W15 A;  3LIR A;  5I3M A;  3KWV C;  3F18 A;  1PWW A;  2OXU A;  2Y6C A;  4Q1L A;  1EB6 A;  2OVZ A;  4JP4 A;  1BUD A;  1QJI A;  2W0D A;  2YB9 A;  3TVC A;  1K7I A;  1GXD A;  3KEK A;  3KHI A;  4AYK A;  3LJT A;  1CXV A;  1CK7 A;  5B5P A;  1BKC E;  4IN9 A;  3V96 B;  1JJ9 A;  2X3A A;  4WZV A;  3TS4 A;  4I03 A;  2J0T A;  3LKA A;  1KBC A;  5D7W A;  3EHX A;  3TT4 A;  1XFW A;  2MZI A;  3LIK A;  3ZUK A;  4PKR A;  3LGP A;  1FLS A;  3DL1 A;  3AYK A;  3EHY A;  1C3I A;  1SU3 A;  5JMY A;  1G05 A;  1PWV A;  4AIG A;  2JIH A;  3O2X A;  1SLN A;  2FV5 A;  4DD8 A;  1I76 A;  2V4B A;  1G12 A;  2K9C A;  4PKQ A;  2O3E A;  1OM7 A;  4XCT A;  3LQ0 A;  1A86 A;  1JAO A;  2AYK A;  3ELM A;  1IAC A;  3GBO A;  2X3B A;  1ZXC A;  1BIW A;  2DDY A;  5LAB A;  1MNC A;  1H71 P;  3ZVS A;  1Z3J A;  1JAN A;  4WK7 A;  2RJP A;  3HDA P;  3KEC A;  2OXW A;  2JNP A;  2I47 A;  2OW9 A;  1D7X A;  5I43 A;  1JAP A;  1MMP A;  3RTS A;  3LUN A;  3WV2 A;  1DTH A;  2CLT A;  2XS3 A;  3EDH A;  3Q2G A;  2N8R A;  1ZS0 A;  1XFV A;  2JSD A;  1CIZ A;  3L0V A;  4PKT A;  4H49 A;  3G5C A;  1D8F A;  4JIJ A;  4IUW A;  1BZS A;  1YOU A;  4FXQ A;  3AIG A;  3OHL A;  3WV1 A;  1JAQ A;  3F15 A;  2Y6D A;  4WKI A;  4GR3 A;  1RM8 A;  3O64 A;  1FBL A;  1CGL A;  1UTZ A;  1OM6 A;  1O0T A;  3HBV P;  1BUV M;  2USN A;  1HFS A;  2DW0 A;  1GE5 A;  3F1A A;  5BOT A;  2PJT A;  5L79 A;  4L63 A;  2QPJ A;  5L7F A;  3UVC A;  2D1O A;  3LJZ A;  3VTG A;  1S4B P;  3OHO A;  1EUB A;  1IAE A;  4GR0 A;  2AIG P;  4HMA A;  3F19 A;  5D1S A;  3B8Z A;  1HV5 A;  4ZR5 A;  4XM6 A;  1IAG A;  1XFZ A;  4R3V A;  1SAT A;  1QIB A;  1JK3 A;  3HDB A;  2A8H A;  1O0Q A;  5I4O A;  1R55 A;  2ERP A;  4QKZ A;  4A7B A;  3L0T A;  2O36 A;  1JKY A;  3K7N A;  4PKV A;  1JIW P;  4JA1 A;  1ND1 A;  830C A;  4H76 A;  4DPE A;  3EDI A;  1QJJ A;  4AUO A;  3N2U A;  5D1U A;  3B2Z A;  4H1Q A;  1FM1 A;  5I0L A;  3TSK A;  4PKW A;  3I7I A;  1I73 A;  2Z2D A;  1A85 A;  1R1H A;  3BA0 A;  1ZTQ A;  1OS9 A;  1Y93 A;  3HBU P;  1YCM A;  3HY9 A;  4GUY A;  3EDG A;  4H84 A;  1HTD A;  4H3X A;  3DNG A;  3KME A;  3E8R A;  4XBH A;  2RJQ A;  1CQR A;  1HOV A;  2SRT A;  3CKI A;  1GKD A;  4FXY P;  1KUF A;  3G42 A;  3RTT A;  2OVX A;  1BKC I;  1Y8J A;  1J7N A;  1Q3A A;  2OY2 A;  1SMP A;  1GE6 A;  4DV8 A;  4WF6 A;  2X7M A;  1CGF A;  2DDF A;  4WKE A;  1UMT A;  2MLS A;  1KUG A;  2WO9 A;  1BKC A;  4CTH A;  3U1R A;  2OXZ A;  1BQQ M;  3LEA A;  3HB2 P;  3DPE A;  5B5O A;  1XUC A;  2XS4 A;  3LK8 A;  5CUH A;  4H30 A;  3WV3 A;  2MLR A;  1R54 A;  1WNI A;  1GO7 P;  4L19 A;  4PKU A;  1IAB A;  3MA2 A;  3HY7 A;  1C7K A;  2MZE A;  1CAQ A;  1I1I P;  3VI1 A;  1XFU A;  1SRP A;  1EAK A;  3F16 A; 
#chains in the Genus database with same CATH topology
 1ATL A;  2DW2 A;  3LIL A;  1C8T A;  456C A;  4JQG A;  2J83 A;  4PKS A;  1K7G A;  1D8M A;  1G9K A;  1HFC A;  1D5J A;  1JIZ A;  1YQY A;  1GE7 A;  1B8Y A;  1R1J A;  1HY7 A;  3LQB A;  4JPA A;  1XFY A;  5BPA A;  1AKL A;  1CGE A;  1PWP A;  4GQL A;  1BSW A;  1USN A;  3HYG A;  5D2B A;  2ERO A;  3LE9 A;  1R1I A;  4G0D A;  3NX7 A;  3ZXH A;  2OW1 A;  1KAP P;  3AYU A;  2CKI A;  1OM8 A;  1YP1 A;  4A3W A;  1Y0V A;  2K2G A;  1B3D A;  4XM7 A;  2W12 A;  2W13 A;  4DF9 A;  5I12 A;  3Q2H A;  1ZVX A;  2X3C A;  1GKC A;  1ZP5 A;  1OO9 A;  1ZXV A;  3B92 A;  4XM8 A;  1QIA A;  966C A;  2WO8 A;  1BQO A;  2W14 A;  2ERQ A;  1SLM A;  1MMR A;  4ON1 A;  1OS2 A;  1GO8 P;  1PWU A;  4EFS A;  1RMZ A;  3DTK A;  3EDZ A;  4GWN A;  3USN A;  2KRJ A;  2OZR A;  4L6T A;  3P24 A;  1OMJ A;  2JT6 A;  4H82 A;  5BOY A;  1XUR A;  1IAA A;  5CZM A;  5D3C A;  3KEJ A;  2OW2 A;  2E3X A;  4HX3 A;  4I35 A;  1IAD A;  1QIC A;  2E2D A;  5I2Z A;  4GF1 A;  4GWM A;  4H2E A;  1KUI A;  3I7G A;  3F17 A;  4FVL A;  3KMC A;  3EWJ A;  1G49 A;  1ROS A;  1MMB A;  3P1V A;  1L6J A;  2OI0 A;  5H8X A;  3K7L A;  3KRY A;  4J4M A;  2OW0 A;  1K7Q A;  3DPF A;  4FU4 A;  1G4K A;  1AST A;  4ILW D;  1BM6 A;  1MMQ A;  1UEA A;  3DWB A;  1QUA A;  2TCL A;  3DSL A;  1KUK A;  4AXQ A;  3N2V A;  4G9L A;  1XUD A;  1UMS A;  1JH1 A;  5CXA A;  3LJG A;  2YIG A;  1DMT A;  2DW1 A;  1OZ9 A;  1UTT A;  4GR8 A;  4IJO A;  2D1N A;  2WOA A;  1PWQ A;  3LMC A;  2OY4 A;  1AF0 A;  2HU6 A;  1XFX A;  2POJ A;  1KUH A;  3LUM A;  1AYK A;  2L0R A;  2FV9 A;  5D1T A;  2MZH A;  2JT5 A;  3SHI A;  2W15 A;  3LIR A;  5I3M A;  3KWV C;  3F18 A;  1PWW A;  2OXU A;  2Y6C A;  4Q1L A;  1EB6 A;  2OVZ A;  4JP4 A;  1BUD A;  1QJI A;  2W0D A;  2YB9 A;  3TVC A;  1K7I A;  1GXD A;  3KEK A;  3KHI A;  4AYK A;  3LJT A;  1CXV A;  1CK7 A;  5B5P A;  1BKC E;  4IN9 A;  3V96 B;  1JJ9 A;  2X3A A;  4WZV A;  3TS4 A;  4I03 A;  2J0T A;  3LKA A;  1KBC A;  4L7A A;  5D7W A;  3EHX A;  3TT4 A;  1XFW A;  2MZI A;  3LIK A;  3ZUK A;  4PKR A;  3LGP A;  1FLS A;  3DL1 A;  3AYK A;  3EHY A;  1C3I A;  1SU3 A;  5JMY A;  1XM5 A;  1G05 A;  1PWV A;  4AIG A;  2JIH A;  3O2X A;  1SLN A;  2FV5 A;  4DD8 A;  1I76 A;  2V4B A;  1G12 A;  2K9C A;  4PKQ A;  2O3E A;  1OM7 A;  4XCT A;  3LQ0 A;  1A86 A;  1JAO A;  2AYK A;  3ELM A;  1IAC A;  3GBO A;  3DTE A;  2X3B A;  1ZXC A;  1BIW A;  2DDY A;  5LAB A;  1MNC A;  1H71 P;  3ZVS A;  1Z3J A;  1JAN A;  4WK7 A;  2RJP A;  3HDA P;  3KEC A;  2OXW A;  2JNP A;  2I47 A;  2OW9 A;  1D7X A;  5I43 A;  1JAP A;  1MMP A;  3RTS A;  3LUN A;  3WV2 A;  1DTH A;  2CLT A;  2XS3 A;  3EDH A;  3Q2G A;  2N8R A;  1TVI A;  1ZS0 A;  1XFV A;  2JSD A;  1CIZ A;  3L0V A;  4PKT A;  4H49 A;  3G5C A;  1D8F A;  4JIJ A;  4IUW A;  1BZS A;  1YOU A;  4FXQ A;  3AIG A;  3OHL A;  3WV1 A;  1JAQ A;  3F15 A;  2Y6D A;  4WKI A;  4GR3 A;  1RM8 A;  3O64 A;  1FBL A;  1XAX A;  1CGL A;  1UTZ A;  1OM6 A;  1O0T A;  3HBV P;  1BUV M;  2USN A;  1HFS A;  2DW0 A;  1GE5 A;  3F1A A;  5BOT A;  2PJT A;  5L79 A;  4L63 A;  2QPJ A;  5L7F A;  3UVC A;  2D1O A;  3LJZ A;  3VTG A;  1S4B P;  3OHO A;  1EUB A;  1IAE A;  4GR0 A;  2AIG P;  4HMA A;  3F19 A;  5D1S A;  3B8Z A;  1HV5 A;  4ZR5 A;  4XM6 A;  1IAG A;  1XFZ A;  4R3V A;  1SAT A;  1QIB A;  1JK3 A;  3HDB A;  2A8H A;  1O0Q A;  5I4O A;  1R55 A;  2ERP A;  4QKZ A;  4A7B A;  3L0T A;  2O36 A;  1JKY A;  3K7N A;  4PKV A;  1JIW P;  4JA1 A;  1ND1 A;  830C A;  4H76 A;  4DPE A;  3EDI A;  1QJJ A;  4AUO A;  3N2U A;  5D1U A;  3B2Z A;  4H1Q A;  1FM1 A;  5I0L A;  3TSK A;  4PKW A;  3I7I A;  1I73 A;  2Z2D A;  1A85 A;  1R1H A;  3BA0 A;  2YUF A;  1ZTQ A;  1OS9 A;  3HY9 A;  1Y93 A;  1YCM A;  3HBU P;  4GUY A;  3EDG A;  4H84 A;  1HTD A;  4H3X A;  3DNG A;  3KME A;  3E8R A;  4XBH A;  2RJQ A;  1CQR A;  1HOV A;  2SRT A;  3CKI A;  1GKD A;  4FXY P;  1KUF A;  3G42 A;  3RTT A;  2OVX A;  1BKC I;  1Y8J A;  1J7N A;  1Q3A A;  2OY2 A;  1SMP A;  1GE6 A;  4DV8 A;  4WF6 A;  2X7M A;  1CGF A;  2DDF A;  4WKE A;  1UMT A;  2MLS A;  1KUG A;  2WO9 A;  1BKC A;  4CTH A;  3U1R A;  2OXZ A;  1BQQ M;  3LEA A;  3HB2 P;  3DPE A;  5B5O A;  1XUC A;  2XS4 A;  3LK8 A;  5CUH A;  4H30 A;  3WV3 A;  2MLR A;  1R54 A;  1WNI A;  1GO7 P;  4L19 A;  4PKU A;  1IAB A;  3MA2 A;  3HY7 A;  3DTI A;  1C7K A;  2MZE A;  1CAQ A;  1I1I P;  3VI1 A;  1XFU A;  1SRP A;  1EAK A;  3F16 A; 
#chains in the Genus database with same CATH homology
 1ATL A;  2DW2 A;  3LIL A;  1C8T A;  456C A;  4JQG A;  2J83 A;  4PKS A;  1K7G A;  1D8M A;  1G9K A;  1HFC A;  1D5J A;  1JIZ A;  1YQY A;  1GE7 A;  1B8Y A;  1R1J A;  1HY7 A;  3LQB A;  4JPA A;  1XFY A;  5BPA A;  1AKL A;  1CGE A;  1PWP A;  4GQL A;  1BSW A;  1USN A;  3HYG A;  5D2B A;  2ERO A;  3LE9 A;  1R1I A;  4G0D A;  3NX7 A;  3ZXH A;  2OW1 A;  1KAP P;  3AYU A;  2CKI A;  1OM8 A;  1YP1 A;  4A3W A;  1Y0V A;  2K2G A;  1B3D A;  4XM7 A;  2W12 A;  2W13 A;  4DF9 A;  5I12 A;  3Q2H A;  1ZVX A;  2X3C A;  1GKC A;  1ZP5 A;  1OO9 A;  1ZXV A;  3B92 A;  4XM8 A;  1QIA A;  966C A;  2WO8 A;  1BQO A;  2W14 A;  2ERQ A;  1SLM A;  1MMR A;  4ON1 A;  1OS2 A;  1GO8 P;  1PWU A;  4EFS A;  1RMZ A;  3DTK A;  3EDZ A;  4GWN A;  3USN A;  2KRJ A;  2OZR A;  4L6T A;  3P24 A;  1OMJ A;  2JT6 A;  4H82 A;  5BOY A;  1XUR A;  1IAA A;  5CZM A;  5D3C A;  3KEJ A;  2OW2 A;  2E3X A;  4HX3 A;  4I35 A;  1IAD A;  1QIC A;  2E2D A;  5I2Z A;  4GF1 A;  4GWM A;  4H2E A;  1KUI A;  3I7G A;  3F17 A;  4FVL A;  3KMC A;  3EWJ A;  1G49 A;  1ROS A;  1MMB A;  3P1V A;  1L6J A;  2OI0 A;  5H8X A;  3K7L A;  3KRY A;  4J4M A;  2OW0 A;  1K7Q A;  3DPF A;  4FU4 A;  1G4K A;  1AST A;  4ILW D;  1BM6 A;  1MMQ A;  1UEA A;  3DWB A;  1QUA A;  2TCL A;  3DSL A;  1KUK A;  4AXQ A;  3N2V A;  4G9L A;  1XUD A;  1UMS A;  1JH1 A;  5CXA A;  3LJG A;  2YIG A;  1DMT A;  2DW1 A;  1UTT A;  4GR8 A;  4IJO A;  2D1N A;  2WOA A;  1PWQ A;  3LMC A;  2OY4 A;  1AF0 A;  2HU6 A;  1XFX A;  2POJ A;  1KUH A;  3LUM A;  1AYK A;  2L0R A;  2FV9 A;  5D1T A;  2MZH A;  2JT5 A;  3SHI A;  2W15 A;  3LIR A;  5I3M A;  3KWV C;  3F18 A;  1PWW A;  2OXU A;  2Y6C A;  4Q1L A;  1EB6 A;  2OVZ A;  4JP4 A;  1BUD A;  1QJI A;  2W0D A;  2YB9 A;  3TVC A;  1K7I A;  1GXD A;  3KEK A;  3KHI A;  4AYK A;  3LJT A;  1CXV A;  1CK7 A;  5B5P A;  1BKC E;  4IN9 A;  3V96 B;  1JJ9 A;  2X3A A;  4WZV A;  3TS4 A;  4I03 A;  2J0T A;  3LKA A;  1KBC A;  4L7A A;  5D7W A;  3EHX A;  3TT4 A;  1XFW A;  2MZI A;  3LIK A;  3ZUK A;  4PKR A;  3LGP A;  1FLS A;  3DL1 A;  3AYK A;  3EHY A;  1C3I A;  1SU3 A;  5JMY A;  1G05 A;  1PWV A;  4AIG A;  2JIH A;  3O2X A;  1SLN A;  2FV5 A;  4DD8 A;  1I76 A;  2V4B A;  1G12 A;  2K9C A;  4PKQ A;  2O3E A;  1OM7 A;  4XCT A;  3LQ0 A;  1A86 A;  1JAO A;  2AYK A;  3ELM A;  1IAC A;  3GBO A;  3DTE A;  2X3B A;  1ZXC A;  1BIW A;  2DDY A;  5LAB A;  1MNC A;  1H71 P;  3ZVS A;  1Z3J A;  1JAN A;  4WK7 A;  2RJP A;  3HDA P;  3KEC A;  2OXW A;  2JNP A;  2I47 A;  2OW9 A;  1D7X A;  5I43 A;  1JAP A;  1MMP A;  3RTS A;  3LUN A;  3WV2 A;  1DTH A;  2CLT A;  2XS3 A;  3EDH A;  3Q2G A;  2N8R A;  1ZS0 A;  1XFV A;  2JSD A;  1CIZ A;  3L0V A;  4PKT A;  4H49 A;  3G5C A;  1D8F A;  4JIJ A;  4IUW A;  1BZS A;  1YOU A;  4FXQ A;  3AIG A;  3OHL A;  3WV1 A;  1JAQ A;  3F15 A;  2Y6D A;  4WKI A;  4GR3 A;  1RM8 A;  3O64 A;  1FBL A;  1CGL A;  1UTZ A;  1OM6 A;  1O0T A;  3HBV P;  1BUV M;  2USN A;  1HFS A;  2DW0 A;  1GE5 A;  3F1A A;  5BOT A;  2PJT A;  5L79 A;  4L63 A;  2QPJ A;  5L7F A;  3UVC A;  2D1O A;  3LJZ A;  3VTG A;  1S4B P;  3OHO A;  1EUB A;  1IAE A;  4GR0 A;  2AIG P;  4HMA A;  3F19 A;  5D1S A;  3B8Z A;  1HV5 A;  4ZR5 A;  4XM6 A;  1IAG A;  1XFZ A;  4R3V A;  1SAT A;  1QIB A;  1JK3 A;  3HDB A;  2A8H A;  1O0Q A;  5I4O A;  1R55 A;  2ERP A;  4QKZ A;  4A7B A;  3L0T A;  2O36 A;  1JKY A;  3K7N A;  4PKV A;  1JIW P;  4JA1 A;  1ND1 A;  830C A;  4H76 A;  4DPE A;  3EDI A;  1QJJ A;  4AUO A;  3N2U A;  5D1U A;  3B2Z A;  4H1Q A;  1FM1 A;  5I0L A;  3TSK A;  4PKW A;  3I7I A;  1I73 A;  2Z2D A;  1A85 A;  1R1H A;  3BA0 A;  2YUF A;  1ZTQ A;  1OS9 A;  1Y93 A;  3HBU P;  1YCM A;  3HY9 A;  4GUY A;  3EDG A;  4H84 A;  1HTD A;  4H3X A;  3DNG A;  3KME A;  3E8R A;  4XBH A;  2RJQ A;  1CQR A;  1HOV A;  2SRT A;  3CKI A;  1GKD A;  4FXY P;  1KUF A;  3G42 A;  3RTT A;  2OVX A;  1BKC I;  1Y8J A;  1J7N A;  1Q3A A;  2OY2 A;  1SMP A;  1GE6 A;  4DV8 A;  4WF6 A;  2X7M A;  1CGF A;  2DDF A;  4WKE A;  1UMT A;  2MLS A;  1KUG A;  2WO9 A;  1BKC A;  4CTH A;  3U1R A;  2OXZ A;  1BQQ M;  3LEA A;  3HB2 P;  3DPE A;  5B5O A;  1XUC A;  2XS4 A;  3LK8 A;  5CUH A;  4H30 A;  3WV3 A;  2MLR A;  1R54 A;  1WNI A;  1GO7 P;  4L19 A;  4PKU A;  1IAB A;  3MA2 A;  3HY7 A;  3DTI A;  1C7K A;  2MZE A;  1CAQ A;  1I1I P;  3VI1 A;  1XFU A;  1SRP A;  1EAK A;  3F16 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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