5I4ZA

Structure of apo omomyc
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
74
structure length
74
Chain Sequence
RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAETQKLISEIDLLRKQNEQLKHKLEQLRNSCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords Myc proto-oncogene protein
publication title OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
pubmed doi rcsb
source organism Homo sapiens
total genus 30
structure length 74
sequence length 74
chains with identical sequence B
ec nomenclature
pdb deposition date 2016-02-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
A PF02344 Myc-LZ Myc leucine zipper domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 5i4zA00
4F3LA 1NLWB 1HLOA 1NKPA 1MDYA 1NLWA 1R05A 3U5VA 5I4ZA 2LFHA 5I50A 2QL2B 4ATHA 5EYOA 2QL2A 4H10B 4H10A 1AN2A 2YPBB 2YPAB 1AM9A 3MUJA 2YPAA 4ATIA 2YPBA 2MH3A 1MDYB 1A0AA 1UKLC 1AN4A 4ATKA 4F3LB 1NKPB 4AYAA
chains in the Genus database with same CATH superfamily
4F3LA 1NLWB 1HLOA 1NKPA 1MDYA 1NLWA 1R05A 3U5VA 5I4ZA 2LFHA 5I50A 2QL2B 4ATHA 5EYOA 2QL2A 4H10B 4H10A 1AN2A 2YPBB 1K1FA 2YPAB 1AM9A 3MUJA 2YPAA 4ATIA 2YPBA 2MH3A 1MDYB 1A0AA 1UKLC 1AN4A 4ATKA 1ZZAA 4F3LB 1NKPB 4AYAA
chains in the Genus database with same CATH topology
4F3LA 1NLWB 1HLOA 1NKPA 1MDYA 1NLWA 1R05A 3U5VA 5I4ZA 2LFHA 5I50A 2QL2B 4ATHA 5EYOA 2QL2A 4H10B 4H10A 1AN2A 2YPBB 2YPAB 1AM9A 3MUJA 2YPAA 4ATIA 2YPBA 2MH3A 1MDYB 1A0AA 1UKLC 1AN4A 4ATKA 4F3LB 1NKPB 4AYAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F3L A;  1NLW B;  1HLO A;  1NKP A;  1MDY A;  1NLW A;  1R05 A;  3U5V A;  5I4Z A;  2LFH A;  5I50 A;  2QL2 B;  4ATH A;  5EYO A;  2QL2 A;  4H10 B;  4H10 A;  1AN2 A;  2YPB B;  2YPA B;  1AM9 A;  3MUJ A;  2YPA A;  4ATI A;  2YPB A;  2MH3 A;  1MDY B;  1A0A A;  1UKL C;  1AN4 A;  4ATK A;  4F3L B;  1NKP B;  4AYA A; 
#chains in the Genus database with same CATH topology
 4F3L A;  1NLW B;  1HLO A;  1NKP A;  1MDY A;  1NLW A;  1R05 A;  3U5V A;  5I4Z A;  2LFH A;  5I50 A;  2QL2 B;  4ATH A;  5EYO A;  2QL2 A;  4H10 B;  4H10 A;  1AN2 A;  2YPB B;  1K1F A;  2YPA B;  1AM9 A;  3MUJ A;  2YPA A;  4ATI A;  2YPB A;  2MH3 A;  1MDY B;  1A0A A;  1UKL C;  1AN4 A;  4ATK A;  1ZZA A;  4F3L B;  1NKP B;  4AYA A; 
#chains in the Genus database with same CATH homology
 4F3L A;  1NLW B;  1HLO A;  1NKP A;  1MDY A;  1NLW A;  1R05 A;  3U5V A;  5I4Z A;  2LFH A;  5I50 A;  2QL2 B;  4ATH A;  5EYO A;  2QL2 A;  4H10 B;  4H10 A;  1AN2 A;  2YPB B;  2YPA B;  1AM9 A;  3MUJ A;  2YPA A;  4ATI A;  2YPB A;  2MH3 A;  1MDY B;  1A0A A;  1UKL C;  1AN4 A;  4ATK A;  4F3L B;  1NKP B;  4AYA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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