5IDNB

Cdk8-cycc in complex with [(s)-2-(4-chloro-phenyl)-pyrrolidin-1-yl]-(3-methyl-1h-pyrazolo[3,4-b]pyridin-5-yl)-methanone
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
267
structure length
267
Chain Sequence
DKAMAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Cyclin-dependent kinase 8
total genus 94
structure length 267
sequence length 267
ec nomenclature
pdb deposition date 2016-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00134 Cyclin_N Cyclin, N-terminal domain
B PF16899 Cyclin_C_2 Cyclin C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 5idnB02
1.10.472.10 Mainly Alpha Orthogonal Bundle Cyclin A; domain 1 Cyclin-like 5idnB01
2IW8B 1P5EB 1VINA 3M03A 5EFQB 4G6LB 3BHUB 1GUXA 4BCNB 2C5XB 2UUEB 4BCJB 4CFXB 1UNLD 2IW9B 2JGZB 2W99A 3MI9B 2UZBB 4ROEA 4EOLB 2CCIB 1OL1B 5ACBA 4CFMB 3TNHB 1OI9B 4YOZA 5LQFB 5CEIB 3EOCB 3F5XB 4OGRB 5HQ0B 1H27B 4F6UB 3TN8B 5HBEB 1C9BA 2WMBB 1OKVB 4IMYB 5HBHB 4BCFB 4EOIB 2PK2A 1OIYB 3DOGB 1BU2A 4F6SB 4F7LB 3QHRB 3EIDB 3MY1B 4RODA 5I5ZB 2UZDB 2B9RA 1OIUB 3EJ1B 2IVXA 4YOOA 1H24B 4NSTB 5BNJB 5HVYB 4EC9B 3H4CA 2CJMB 3BLRB 1H1QB 1FINB 4CFWB 2C5NB 4II5B 1H1SB 4F70B 3G33B 2WHBB 1H1RB 4OR5B 2W9ZA 2WIHB 1N4MA 2UZLB 2I53A 2WPAB 1GH6B 2PMIB 3DDQB 2X1NB 5IF1B 2EUFA 4BCMD 1GY3B 1H25B 4CFNB 4EOPB 3TNIB 4EOKB 3DDPB 2C5VB 4KRDB 4YC3B 3O0GD 2F2CA 1D3UB 2W2HA 5HBJB 4BCKB 4CFUD 4TTHA 1H4LD 1G3NC 3QHWB 5IDPB 1UNHD 2C6TB 4EC8B 4FX3B 1OL2B 2IW6B 4KRCB 3LQ5B 4EOOB 1W98B 3RGFB 4CFUB 4BCQD 2CCHB 4EOSB 2PK9B 2W96A 4YOSA 1AISB 2C5OB 2PHGA 1JKWA 1JSTB 2WFYB 3BLQB 4ELLA 2UZEB 4EORB 1H26B 4F6WB 1H1PB 5FGKB 1OKWB 1ZP2A 3K7AM 4EONB 4EOMB 3TNWB 2C4GB 2WIPB 4BCND 3BHVB 1VOLA 2R7GA 1JOWA 5HNBB 5L2WB 1E9HB 1XO2A 4F7SB 2G9XB 4ROCA 1OGUB 2I40B 4UN0A 1PKDB 4BCMB 1AD6A 2BPMB 3BHTB 5CYIB 2V22B 4BCPB 1TFBA 4BCOB 4EOQB 4F7JB 1FVVB 1QMZB 4I3ZB 4F7NB 4BCGB 3MIAB 1VYWB 2BKZB 2WMAB 5LMKB 1KXUA 2W9FA 4BCHB 1O9KB 3BLHB 4EOJB 4BCIB 4Y72B 3POMA 4CXAB 4ELJA 1H28B 1F5QB 4BCQB 1URCB 5ICPB 4CFVB 2WEVB 4CRLB 5IDNB 1GUXB 2WXVB 3MY5B 2QDJA 1JSUB 1UNGD 1O9KA
chains in the Genus database with same CATH superfamily
4LOCA 1UGQB 2IW8B 3WVEB 1UGPB 4BCNB 4BCJB 1IREB 3MI9B 2UZBB 4MIMA 4CFMB 4YOZA 3F5XB 3TN8B 1C9BA 5HBHB 4BCFB 4F6SB 2PK2A 3DOGB 3X28B 5I5ZB 2UZDB 2B9RA 5BNJB 2CZ1B 3A8MB 4II5B 5DQVA 3DDQB 2PMIB 5IF1B 4JX5A 4CFNB 4KRDB 4MFDA 4CFUD 1H4LD 2DXBB 1G3NC 3PO3S 4EC8B 3QZ9B 1W98B 3BG3A 3A8HB 1AISB 2KMGA 3TW6A 4BY1X 3QYGB 1OKWB 2CYZB 2DD4B 3K7AM 4EONB 4EOMB 3TNWB 3VYHB 3BHVB 2R7GA 4NC6A 5HNBB 4HLQA 3HO8A 2CZ7B 2DMEA 2BPMB 1QLBA 5CYIB 4F7JB 1VYWB 2WMAB 1KXUA 3GTMS 3VKHA 4ZGDB 1H28B 1URCB 4CFVB 3MY5B 1UNGD 4EOKB 1O9KA 4FM4B 2D0QB 3M03A 5EFQB 2DXCB 4CFXB 1UNLD 1FKMA 2CZ6B 2W99A 4ROEA 4QSHA 5LQFB 5HQ0B 2WMBB 1OKVB 3DTOA 4IMYB 1OIYB 4BBRM 3VYGB 2QFZA 3X24B 4EC9B 3QZ5B 1FINB 4CFWB 4F70B 3QXEB 4OR5B 4JX4A 2UZLB 2I53A 2X1NB 4BCMD 4ZGEB 3DDPB 2C5VB 1ENWA 4ZGJB 3HZJA 1UGSB 2C6TB 4FX3B 1OL2B 3LQ5B 4CFUB 3HHTB 4JX6A 1JSTB 2WFYB 4EORB 4F6WB 2ZPHB 1TD6A 2QDYB 4BCND 4BBSM 3B57A 4OB3B 4AKHA 1JOWA 5L2WB 1E9HB 1XO2A 4F7SB 1OGUB 1AD6A 4EOQB 1FVVB 1QMZB 2BS3A 2DPPB 2KR6A 4Y72B 3POMA 4CXAB 4ELJA 2ZCFB 3QYEA 4BCQB 2WEVB 4CRLB 5IDNB 4OB2B 2QDJA 3A8OB 3BG9A 1VINA 3DL1A 3BHUB 4AKIA 1GUXA 2AHJB 2C5XB 2UUEB 3X20B 2IW9B 2CCIB 1OL1B 3TNHB 3HB9A 5CEIB 2ZZDB 1H27B 4F6UB 5HBEB 4F7LB 4EOIB 1BU2A 3BG5A 3QHRB 3EIDB 3MY1B 4RODA 3EJ1B 2IVXA 4YOOA 5HVYB 4Z6YA 3H4CA 3BLRB 5DQWA 3VKGA 2C5NB 1AHJB 3A8GB 2WIHB 1N4MA 4HL4A 1GY3B 1H25B 3TNIB 1D3UB 2W2HA 5HBJB 4TTHA 1UNHD 2LW4A 4EOOB 2ZPEB 1UGRB 2CCHB 4EOSB 4YOSA 2C5OB 2PHGA 1JKWA 2QQ8A 2UZEB 2IN3A 1H26B 4AKGA 5FGKB 1VOLA 4ROCA 2PJQA 2G9XB 5IHYA 4UN0A 2I40B 3BHTB 2V22B 4BCPB 4F7NB 4BCGB 3QYBA 3MIAB 1O9KB 2WJ9A 3BLHB 3A8LB 4AI6A 2ZPGB 2ZPBB 3X25B 1P5EB 2QF7A 2BS4A 4G6LB 4MFEA 2JGZB 4EOLB 5ACBA 1OI9B 2G77A 3EOCB 4OGRB 4HNTA 2ZPFB 4BY7X 4OB0B 1OIUB 4M6VA 1H24B 4NSTB 2CJMB 3WVDB 1H1QB 3X26B 4OB1B 1H1SB 1V29B 3G33B 2WHBB 1H1RB 2W9ZA 4BXXX 2WPAB 1GH6B 2CZ0B 2QGSA 2EUFA 4EOPB 3KHIA 4YC3B 3O0GD 2F2CA 4BCKB 1E7PA 3QHWB 5IDPB 2ZPIB 2IW6B 4KRCB 3RGFB 4BCQD 3NDQA 3TW7A 3HBLA 2PK9B 2W96A 4HNVA 3QWLA 2BS2A 3BLQB 4ELLA 5EJCA 1H1PB 1ZP2A 2C4GB 2WIPB 2DD5B 4BCMB 1PKDB 3DJBA 1TFBA 4BCOB 4I3ZB 2BKZB 5LMKB 2W9FA 4BCHB 4EOJB 4BCIB 4HNUA 1F5QB 5ICPB 1GUXB 2WXVB 1JSUB 3QYHB
chains in the Genus database with same CATH topology
2IW8B 1P5EB 1VINA 3M03A 5EFQB 4G6LB 3BHUB 1GUXA 4BCNB 2C5XB 2UUEB 4BCJB 4CFXB 1UNLD 2IW9B 2JGZB 2W99A 3MI9B 2UZBB 4ROEA 4EOLB 2CCIB 1OL1B 5ACBA 4CFMB 3TNHB 1OI9B 4YOZA 5LQFB 5CEIB 3EOCB 3F5XB 4OGRB 5HQ0B 1H27B 4F6UB 3TN8B 5HBEB 1C9BA 2WMBB 1OKVB 4IMYB 5HBHB 4BCFB 4EOIB 2PK2A 1OIYB 3DOGB 1BU2A 4F6SB 4F7LB 3QHRB 3EIDB 3MY1B 4RODA 5I5ZB 2UZDB 2B9RA 1OIUB 3EJ1B 2IVXA 4YOOA 1H24B 4NSTB 5BNJB 5HVYB 4EC9B 3H4CA 2CJMB 3BLRB 1H1QB 1FINB 4CFWB 2C5NB 4II5B 1H1SB 4F70B 3G33B 2WHBB 1H1RB 4OR5B 2W9ZA 2WIHB 1N4MA 2UZLB 2I53A 2WPAB 1GH6B 2PMIB 3DDQB 2X1NB 5IF1B 2EUFA 4BCMD 1GY3B 1H25B 4CFNB 4EOPB 3TNIB 4EOKB 3DDPB 2C5VB 4KRDB 4YC3B 3O0GD 2F2CA 1D3UB 2W2HA 5HBJB 4BCKB 4CFUD 4TTHA 1H4LD 1G3NC 3QHWB 5IDPB 1UNHD 2C6TB 4EC8B 4FX3B 1OL2B 2IW6B 4KRCB 3LQ5B 4EOOB 1W98B 3RGFB 4CFUB 4BCQD 2CCHB 4EOSB 2PK9B 2W96A 4YOSA 1AISB 2C5OB 2PHGA 1JKWA 1JSTB 2WFYB 3BLQB 4ELLA 2UZEB 4EORB 1H26B 4F6WB 1H1PB 5FGKB 1OKWB 1ZP2A 3K7AM 4EONB 4EOMB 3TNWB 2C4GB 2WIPB 4BCND 3BHVB 1VOLA 2R7GA 1JOWA 5HNBB 5L2WB 1E9HB 1XO2A 4F7SB 2G9XB 4ROCA 1OGUB 2I40B 4UN0A 1PKDB 4BCMB 1AD6A 2BPMB 3BHTB 5CYIB 2V22B 4BCPB 1TFBA 4BCOB 4EOQB 4F7JB 1FVVB 1QMZB 4I3ZB 4F7NB 4BCGB 3MIAB 1VYWB 2BKZB 2WMAB 5LMKB 1KXUA 2W9FA 4BCHB 1O9KB 3BLHB 4EOJB 4BCIB 4Y72B 3POMA 4CXAB 4ELJA 1H28B 1F5QB 4BCQB 1URCB 5ICPB 4CFVB 2WEVB 4CRLB 5IDNB 1GUXB 2WXVB 3MY5B 2QDJA 1JSUB 1UNGD 1O9KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IW8 B;  1P5E B;  1VIN A;  3M03 A;  5EFQ B;  4G6L B;  3BHU B;  1GUX A;  4BCN B;  2C5X B;  2UUE B;  4BCJ B;  4CFX B;  1UNL D;  2IW9 B;  2JGZ B;  2W99 A;  3MI9 B;  2UZB B;  4ROE A;  4EOL B;  2CCI B;  1OL1 B;  5ACB A;  4CFM B;  3TNH B;  1OI9 B;  4YOZ A;  5LQF B;  5CEI B;  3EOC B;  3F5X B;  4OGR B;  5HQ0 B;  1H27 B;  4F6U B;  3TN8 B;  5HBE B;  1C9B A;  2WMB B;  1OKV B;  4IMY B;  5HBH B;  4BCF B;  4EOI B;  2PK2 A;  1OIY B;  3DOG B;  1BU2 A;  4F6S B;  4F7L B;  3QHR B;  3EID B;  3MY1 B;  4ROD A;  5I5Z B;  2UZD B;  2B9R A;  1OIU B;  3EJ1 B;  2IVX A;  4YOO A;  1H24 B;  4NST B;  5BNJ B;  5HVY B;  4EC9 B;  3H4C A;  2CJM B;  3BLR B;  1H1Q B;  1FIN B;  4CFW B;  2C5N B;  4II5 B;  1H1S B;  4F70 B;  3G33 B;  2WHB B;  1H1R B;  4OR5 B;  2W9Z A;  2WIH B;  1N4M A;  2UZL B;  2I53 A;  2WPA B;  1GH6 B;  2PMI B;  3DDQ B;  2X1N B;  5IF1 B;  2EUF A;  4BCM D;  1GY3 B;  1H25 B;  4CFN B;  4EOP B;  3TNI B;  4EOK B;  3DDP B;  2C5V B;  4KRD B;  4YC3 B;  3O0G D;  2F2C A;  1D3U B;  2W2H A;  5HBJ B;  4BCK B;  4CFU D;  4TTH A;  1H4L D;  1G3N C;  3QHW B;  5IDP B;  1UNH D;  2C6T B;  4EC8 B;  4FX3 B;  1OL2 B;  2IW6 B;  4KRC B;  3LQ5 B;  4EOO B;  1W98 B;  3RGF B;  4CFU B;  4BCQ D;  2CCH B;  4EOS B;  2PK9 B;  2W96 A;  4YOS A;  1AIS B;  2C5O B;  2PHG A;  1JKW A;  1JST B;  2WFY B;  3BLQ B;  4ELL A;  2UZE B;  4EOR B;  1H26 B;  4F6W B;  1H1P B;  5FGK B;  1OKW B;  1ZP2 A;  3K7A M;  4EON B;  4EOM B;  3TNW B;  2C4G B;  2WIP B;  4BCN D;  3BHV B;  1VOL A;  2R7G A;  1JOW A;  5HNB B;  5L2W B;  1E9H B;  1XO2 A;  4F7S B;  2G9X B;  4ROC A;  1OGU B;  2I40 B;  4UN0 A;  1PKD B;  4BCM B;  1AD6 A;  2BPM B;  3BHT B;  5CYI B;  2V22 B;  4BCP B;  1TFB A;  4BCO B;  4EOQ B;  4F7J B;  1FVV B;  1QMZ B;  4I3Z B;  4F7N B;  4BCG B;  3MIA B;  1VYW B;  2BKZ B;  2WMA B;  5LMK B;  1KXU A;  2W9F A;  4BCH B;  1O9K B;  3BLH B;  4EOJ B;  4BCI B;  4Y72 B;  3POM A;  4CXA B;  4ELJ A;  1H28 B;  1F5Q B;  4BCQ B;  1URC B;  5ICP B;  4CFV B;  2WEV B;  4CRL B;  5IDN B;  1GUX B;  2WXV B;  3MY5 B;  2QDJ A;  1JSU B;  1UNG D;  1O9K A; 
#chains in the Genus database with same CATH topology
 4LOC A;  1UGQ B;  2IW8 B;  3WVE B;  1UGP B;  4BCN B;  4BCJ B;  1IRE B;  3MI9 B;  2UZB B;  4MIM A;  4CFM B;  4YOZ A;  3F5X B;  3TN8 B;  1C9B A;  5HBH B;  4BCF B;  4F6S B;  2PK2 A;  3DOG B;  3X28 B;  5I5Z B;  2UZD B;  2B9R A;  5BNJ B;  2CZ1 B;  3A8M B;  4II5 B;  5DQV A;  3DDQ B;  2PMI B;  5IF1 B;  4JX5 A;  4CFN B;  4KRD B;  4MFD A;  4CFU D;  1H4L D;  2DXB B;  1G3N C;  3PO3 S;  4EC8 B;  3QZ9 B;  1W98 B;  3BG3 A;  3A8H B;  1AIS B;  2KMG A;  3TW6 A;  4BY1 X;  3QYG B;  1OKW B;  2CYZ B;  2DD4 B;  3K7A M;  4EON B;  4EOM B;  3TNW B;  3VYH B;  3BHV B;  2R7G A;  4NC6 A;  5HNB B;  4HLQ A;  3HO8 A;  2CZ7 B;  2DME A;  2BPM B;  1QLB A;  5CYI B;  4F7J B;  1VYW B;  2WMA B;  1KXU A;  3GTM S;  3VKH A;  4ZGD B;  1H28 B;  1URC B;  4CFV B;  3MY5 B;  1UNG D;  4EOK B;  1O9K A;  4FM4 B;  2D0Q B;  3M03 A;  5EFQ B;  2DXC B;  4CFX B;  1UNL D;  1FKM A;  2CZ6 B;  2W99 A;  4ROE A;  4QSH A;  5LQF B;  5HQ0 B;  2WMB B;  1OKV B;  3DTO A;  4IMY B;  1OIY B;  4BBR M;  3VYG B;  2QFZ A;  3X24 B;  4EC9 B;  3QZ5 B;  1FIN B;  4CFW B;  4F70 B;  3QXE B;  4OR5 B;  4JX4 A;  2UZL B;  2I53 A;  2X1N B;  4BCM D;  4ZGE B;  3DDP B;  2C5V B;  1ENW A;  4ZGJ B;  3HZJ A;  1UGS B;  2C6T B;  4FX3 B;  1OL2 B;  3LQ5 B;  4CFU B;  3HHT B;  4JX6 A;  1JST B;  2WFY B;  4EOR B;  4F6W B;  2ZPH B;  1TD6 A;  2QDY B;  4BCN D;  4BBS M;  3B57 A;  4OB3 B;  4AKH A;  1JOW A;  5L2W B;  1E9H B;  1XO2 A;  4F7S B;  1OGU B;  1AD6 A;  4EOQ B;  1FVV B;  1QMZ B;  2BS3 A;  2DPP B;  2KR6 A;  4Y72 B;  3POM A;  4CXA B;  4ELJ A;  2ZCF B;  3QYE A;  4BCQ B;  2WEV B;  4CRL B;  5IDN B;  4OB2 B;  2QDJ A;  3A8O B;  3BG9 A;  1VIN A;  3DL1 A;  3BHU B;  4AKI A;  1GUX A;  2AHJ B;  2C5X B;  2UUE B;  3X20 B;  2IW9 B;  2CCI B;  1OL1 B;  3TNH B;  3HB9 A;  5CEI B;  2ZZD B;  1H27 B;  4F6U B;  5HBE B;  4F7L B;  4EOI B;  1BU2 A;  3BG5 A;  3QHR B;  3EID B;  3MY1 B;  4ROD A;  3EJ1 B;  2IVX A;  4YOO A;  5HVY B;  4Z6Y A;  3H4C A;  3BLR B;  5DQW A;  3VKG A;  2C5N B;  1AHJ B;  3A8G B;  2WIH B;  1N4M A;  4HL4 A;  1GY3 B;  1H25 B;  3TNI B;  1D3U B;  2W2H A;  5HBJ B;  4TTH A;  1UNH D;  2LW4 A;  4EOO B;  2ZPE B;  1UGR B;  2CCH B;  4EOS B;  4YOS A;  2C5O B;  2PHG A;  1JKW A;  2QQ8 A;  2UZE B;  2IN3 A;  1H26 B;  4AKG A;  5FGK B;  1VOL A;  4ROC A;  2PJQ A;  2G9X B;  5IHY A;  4UN0 A;  2I40 B;  3BHT B;  2V22 B;  4BCP B;  4F7N B;  4BCG B;  3QYB A;  3MIA B;  1O9K B;  2WJ9 A;  3BLH B;  3A8L B;  4AI6 A;  2ZPG B;  2ZPB B;  3X25 B;  1P5E B;  2QF7 A;  2BS4 A;  4G6L B;  4MFE A;  2JGZ B;  4EOL B;  5ACB A;  1OI9 B;  2G77 A;  3EOC B;  4OGR B;  4HNT A;  2ZPF B;  4BY7 X;  4OB0 B;  1OIU B;  4M6V A;  1H24 B;  4NST B;  2CJM B;  3WVD B;  1H1Q B;  3X26 B;  4OB1 B;  1H1S B;  1V29 B;  3G33 B;  2WHB B;  1H1R B;  2W9Z A;  4BXX X;  2WPA B;  1GH6 B;  2CZ0 B;  2QGS A;  2EUF A;  4EOP B;  3KHI A;  4YC3 B;  3O0G D;  2F2C A;  4BCK B;  1E7P A;  3QHW B;  5IDP B;  2ZPI B;  2IW6 B;  4KRC B;  3RGF B;  4BCQ D;  3NDQ A;  3TW7 A;  3HBL A;  2PK9 B;  2W96 A;  4HNV A;  3QWL A;  2BS2 A;  3BLQ B;  4ELL A;  5EJC A;  1H1P B;  1ZP2 A;  2C4G B;  2WIP B;  2DD5 B;  4BCM B;  1PKD B;  3DJB A;  1TFB A;  4BCO B;  4I3Z B;  2BKZ B;  5LMK B;  2W9F A;  4BCH B;  4EOJ B;  4BCI B;  4HNU A;  1F5Q B;  5ICP B;  1GUX B;  2WXV B;  1JSU B;  3QYH B; 
#chains in the Genus database with same CATH homology
 2IW8 B;  1P5E B;  1VIN A;  3M03 A;  5EFQ B;  4G6L B;  3BHU B;  1GUX A;  4BCN B;  2C5X B;  2UUE B;  4BCJ B;  4CFX B;  1UNL D;  2IW9 B;  2JGZ B;  2W99 A;  3MI9 B;  2UZB B;  4ROE A;  4EOL B;  2CCI B;  1OL1 B;  5ACB A;  4CFM B;  3TNH B;  1OI9 B;  4YOZ A;  5LQF B;  5CEI B;  3EOC B;  3F5X B;  4OGR B;  5HQ0 B;  1H27 B;  4F6U B;  3TN8 B;  5HBE B;  1C9B A;  2WMB B;  1OKV B;  4IMY B;  5HBH B;  4BCF B;  4EOI B;  2PK2 A;  1OIY B;  3DOG B;  1BU2 A;  4F6S B;  4F7L B;  3QHR B;  3EID B;  3MY1 B;  4ROD A;  5I5Z B;  2UZD B;  2B9R A;  1OIU B;  3EJ1 B;  2IVX A;  4YOO A;  1H24 B;  4NST B;  5BNJ B;  5HVY B;  4EC9 B;  3H4C A;  2CJM B;  3BLR B;  1H1Q B;  1FIN B;  4CFW B;  2C5N B;  4II5 B;  1H1S B;  4F70 B;  3G33 B;  2WHB B;  1H1R B;  4OR5 B;  2W9Z A;  2WIH B;  1N4M A;  2UZL B;  2I53 A;  2WPA B;  1GH6 B;  2PMI B;  3DDQ B;  2X1N B;  5IF1 B;  2EUF A;  4BCM D;  1GY3 B;  1H25 B;  4CFN B;  4EOP B;  3TNI B;  4EOK B;  3DDP B;  2C5V B;  4KRD B;  4YC3 B;  3O0G D;  2F2C A;  1D3U B;  2W2H A;  5HBJ B;  4BCK B;  4CFU D;  4TTH A;  1H4L D;  1G3N C;  3QHW B;  5IDP B;  1UNH D;  2C6T B;  4EC8 B;  4FX3 B;  1OL2 B;  2IW6 B;  4KRC B;  3LQ5 B;  4EOO B;  1W98 B;  3RGF B;  4CFU B;  4BCQ D;  2CCH B;  4EOS B;  2PK9 B;  2W96 A;  4YOS A;  1AIS B;  2C5O B;  2PHG A;  1JKW A;  1JST B;  2WFY B;  3BLQ B;  4ELL A;  2UZE B;  4EOR B;  1H26 B;  4F6W B;  1H1P B;  5FGK B;  1OKW B;  1ZP2 A;  3K7A M;  4EON B;  4EOM B;  3TNW B;  2C4G B;  2WIP B;  4BCN D;  3BHV B;  1VOL A;  2R7G A;  1JOW A;  5HNB B;  5L2W B;  1E9H B;  1XO2 A;  4F7S B;  2G9X B;  4ROC A;  1OGU B;  2I40 B;  4UN0 A;  1PKD B;  4BCM B;  1AD6 A;  2BPM B;  3BHT B;  5CYI B;  2V22 B;  4BCP B;  1TFB A;  4BCO B;  4EOQ B;  4F7J B;  1FVV B;  1QMZ B;  4I3Z B;  4F7N B;  4BCG B;  3MIA B;  1VYW B;  2BKZ B;  2WMA B;  5LMK B;  1KXU A;  2W9F A;  4BCH B;  1O9K B;  3BLH B;  4EOJ B;  4BCI B;  4Y72 B;  3POM A;  4CXA B;  4ELJ A;  1H28 B;  1F5Q B;  4BCQ B;  1URC B;  5ICP B;  4CFV B;  2WEV B;  4CRL B;  5IDN B;  1GUX B;  2WXV B;  3MY5 B;  2QDJ A;  1JSU B;  1UNG D;  1O9K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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